Fact-checked by Grok 2 weeks ago

Yakovlevian torque

Yakovlevian torque is a typical pattern of structural asymmetry in the human brain, characterized by a subtle counterclockwise torsion that positions the right frontal lobe slightly forward (right frontal petalia) and the left occipital lobe slightly backward (left occipital petalia), often accompanied by leftward occipital bending.^[1] This geometric distortion forms a continuum of developmental twisting extending from the spinal cord to the telencephalon and is considered a fundamental feature of cerebral lateralization.^[2] Named after the Russian-American neuroanatomist Paul Ivan Yakovlev, who first described it in the late 1930s based on postmortem examinations, the torque was later quantified in vivo through neuroimaging techniques starting in the 1970s.^[3]^[2] The torque exhibits dynamic morphological changes across the lifespan, with evidence of attenuation in certain brain regions from ages 3 to 81, reflecting ongoing neurodevelopmental and aging processes.^[2] It is influenced by biological factors including sex differences, with males showing more pronounced expressions, and handedness, where right-handers tend to display greater torque extent compared to left-handers.^[4] Associations have been identified with cognitive functions, such as enhanced verbal abilities in individuals with stronger torque, and neuropsychiatric conditions like schizophrenia, where deviations in torque magnitude may contribute to altered brain lateralization.^[2] Recent large-scale magnetic resonance imaging (MRI) studies involving over 24,000 participants have confirmed its widespread occurrence in the human population and estimated its heritability at up to 56%, based on pedigree analyses and single-nucleotide polymorphism data.^[2] Emerging research highlights the torque's potential uniqueness to humans, as it appears absent in nonhuman primates and other species, suggesting an evolutionary adaptation tied to advanced cognitive capacities like language and tool use.^[3] In cases of situs inversus totalis—a rare congenital reversal of visceral organs—the brain torque direction reverses, mirroring the overall body asymmetry and correlating with volumetric differences in the transverse sinuses, which may mechanically influence its formation during embryogenesis.^[1] These findings underscore the torque's role in integrating genetic, hormonal, and biomechanical factors to shape hemispheric specialization, with implications for understanding neurodevelopmental disorders and human evolution.^[2]^[1]

Definition and Anatomy

Core Structural Features

Yakovlevian torque refers to a subtle, consistent structural asymmetry in the human brain characterized by an anterior displacement of the right frontal lobe relative to the left hemisphere and a posterior displacement of the left occipital lobe, creating an overall counterclockwise twist when viewed from above. This pattern is observed in approximately 80-90% of the population.^[5] This torque manifests as a geometric distortion without significantly altering total brain volume, contributing to the brain's inherent hemispheric laterality.^[4] The pattern is evident in the protrusion of cerebral tissue across the midline, with the right frontal pole extending leftward and the left occipital pole extending rightward.^[3] Central to this torque are the petalias, or localized bulges in cortical regions: the right frontal petalia involves an outward bulging of the right frontal lobe, while the left occipital petalia features a similar protrusion in the left occipital lobe.^[5] These petalias are accompanied by asymmetry in the lateral sulcus, where the left Sylvian fissure tends to be longer, higher positioned, and more horizontally oriented compared to the right, which is shorter and more vertically inclined.^[4] Together, these features produce a rotational effect that aligns frontal and occipital regions in opposing directions, enhancing the brain's overall asymmetry along the anterior-posterior axis.^[3] The term "Yakovlevian torque" honors neuroanatomist Paul Ivan Yakovlev, who first described this warping of brain structure in postmortem examinations during the late 1930s.^[3] Yakovlev's observations, later elaborated in works from the 1960s, highlighted the torque as a normative feature of human cerebral anatomy, distinct from pathological distortions.^[4] Visually, when the brain is sectioned coronally or viewed superiorly, the torque appears as a gentle torsion, with the right hemisphere shifted forward and the left backward, underscoring its role in establishing baseline hemispheric specialization without volumetric imbalance.^[5]

Measurement Techniques

The primary methods for identifying and quantifying Yakovlevian torque rely on structural magnetic resonance imaging (MRI), particularly T1-weighted scans, which enable non-invasive three-dimensional visualization of brain asymmetries in vivo.^[5] Post-mortem dissection techniques, as originally employed by Yakovlev and Rakic in their examination of human brains, provide direct anatomical assessment through serial sectioning and macroscopic observation of hemispheric twisting.^[6] These approaches allow researchers to detect the characteristic rightward frontal protrusion (petalia) and leftward occipital protrusion, which contribute to the torque's overall geometry.^[7] Quantitative indices of Yakovlevian torque typically involve calculating the angular deviation between the frontal and occipital poles of the hemispheres, often using 3D reconstruction of MRI data and rotation matrices to model the brain's torsional asymmetry.^[4] For instance, the torque index can be derived by aligning hemispheres in a standardized space and measuring the rotational offset.^[4] Specific protocols incorporate anatomical landmarks such as the central sulcus for midline orientation, the Sylvian fissure for lateral boundary delineation, and petalia measurements to quantify protrusions, as detailed in volumetric asymmetry studies using voxel-based morphometry.^[7] In Toga and Thompson's 2003 analysis, these landmarks were applied to averaged 3D MRI models from right-handed subjects to map torque-related asymmetries across the cortex.^[7] Measurement challenges arise from inter-individual variability influenced by head position during scanning, which can introduce artifacts in asymmetry quantification, and differences in scanner resolution that affect the precision of sulcal and gyral boundaries.^[8] Standardization in coordinate systems like Talairach space is essential to mitigate these issues, enabling consistent alignment across datasets despite variations in brain orientation and size.^[9] Recent advances include automated algorithms for large-scale MRI analysis, such as those implemented in the ENIGMA Consortium's study of 17,141 healthy individuals, which used FreeSurfer software to segment cortical regions and compute asymmetry indices like (L − R)/((L + R)/2) for thickness and surface area, revealing a consistent fronto-occipital torque pattern.^[5] These methods enhance reproducibility by reducing manual intervention and scaling to population-level inferences.^[5]

Functional and Clinical Associations

Relation to Handedness

Yakovlevian torque exhibits a positive association with right-handedness, where stronger torque asymmetry—characterized by greater right frontal and left occipital petalia—is more pronounced in dextrals compared to left- or mixed-handers.^[10] A 2012 literature review of morphometric studies confirmed that handedness-related effects correspond to the extent of this torque, primarily through variations in frontal lobe anatomy, with reduced torque observed in non-right-handers.^[10] Meta-analyses and large-scale imaging studies further support this link, indicating that torque asymmetry accounts for a small portion of the variance in handedness measures, independent of other asymmetries such as planum temporale volume.^[11] For instance, in a cohort of over 24,000 individuals, right-handers displayed significantly greater leftward frontal bending and occipital tissue asymmetry (Cohen's d ≈ 0.14-0.20), while left-handers showed attenuated or opposite patterns (correlation r ≈ 0.14, p < 0.01).^[11] These effects persist after controlling for sex and age, highlighting torque as a modest but reliable predictor of manual laterality.^[11] The underlying mechanisms may involve torque's influence on motor cortex organization, where the right frontal displacement enhances left-hemisphere dominance for precise motor control, aligning with the contralateral control of the right hand.^[10] Neuroimaging evidence suggests this geometric distortion modulates central sulcus shape and asymmetry in premotor areas, facilitating lateralized hand use in right-handers.^[12] Population-level research consistently demonstrates robust torque in right-handed (dextral) groups. In contrast, ambidextrous or mixed-handed individuals often exhibit diminished, reversed, or absent torque.

Links to Neurodevelopmental Disorders

Alterations in Yakovlevian torque have been implicated in neurodevelopmental disorders, particularly persistent developmental stuttering, where reduced or absent typical asymmetries are observed more frequently than in the general population. In a study of boys with developmental stuttering, 79% exhibited atypical brain torque configurations, characterized by reduced right prefrontal and left occipital asymmetries, compared to 36% in age-matched controls; this difference was statistically significant (χ²(1) = 5.3, p = 0.022).^[13] Similarly, in adults with persistent developmental stuttering, the expected rightward prefrontal and leftward occipital petalias were absent across the sample, contrasting with typical patterns in all controls, indicating a higher prevalence of atypical laterality in this disorder.^[14] These findings suggest that deviations from the standard counterclockwise torque may contribute to speech fluency disruptions by altering structural foundations for language processing. The neurological basis for these associations lies in how torque anomalies potentially disrupt perisylvian language networks, which encompass regions critical for speech motor control and fluency. Atypical torque has been linked to reduced asymmetries in prefrontal and occipital lobes, which may impair the integration of frontal-temporal-parietal circuits involved in rapid articulatory sequencing and timing. For instance, MRI-based volumetric analyses show that reduced left occipital petalia in stuttering individuals correlates with diminished asymmetry in Broca's area, a key speech production hub, potentially leading to inefficient motor planning for fluent speech. Supporting evidence from structural MRI studies reinforces these connections, demonstrating that torque direction influences Broca's area volume and asymmetry, which in turn relates to speech motor control deficits in stuttering. In both pediatric and adult cohorts, the absence of typical petalias—such as the left occipital protrusion—coincides with anomalous white matter volumes in language-relevant pathways, suggesting a structural vulnerability that predisposes to developmental speech impairments. While stuttering often co-occurs with non-right-handedness, reflecting broader laterality variations, the specific torque deficits appear to independently contribute to perisylvian network anomalies. Broader implications include the potential use of Yakovlevian torque as a neuroimaging biomarker for identifying at-risk individuals early in development, enabling targeted interventions to mitigate speech disorders; however, causality between torque alterations and stuttering remains unproven, with ongoing research needed to clarify directional influences.

Connections to Mood Disorders

Research using magnetic resonance imaging (MRI) has identified a significant association between Yakovlevian torque and bipolar disorder, particularly through increased prevalence of occipital bending, a morphological manifestation of the torque. In a study of 35 patients with bipolar disorder and 36 healthy controls, occipital bending was observed in 34.3% of the patient group compared to 8.3% of controls, representing a fourfold increase.^[15] This asymmetry is characterized by a pronounced left-occipital petalia, where the left occipital lobe protrudes beyond the right, potentially reflecting exaggerated torque in affected individuals.^[15] Hypothesized mechanisms suggest that enhanced Yakovlevian torque may amplify structural asymmetries between limbic and prefrontal regions, thereby contributing to mood instability in bipolar disorder. For instance, the bending associated with torque could exert mechanical pressure on subcortical structures such as the hippocampus, leading to volume reductions observed in psychiatric conditions.^[15] Additionally, links to white matter disruptions have been proposed, with studies indicating altered integrity in occipital and prefrontal white matter tracts among bipolar patients, potentially exacerbating dysregulation in mood-related circuits.^[15] Further correlations extend to other psychiatric conditions, including variations in torque among individuals with schizophrenia, where 1990s neuroimaging studies revealed anomalies in brain asymmetry, such as reduced or reversed patterns in patients compared to controls.^[14] Clinically, Yakovlevian torque has been proposed as a potential endophenotype for mood disorder risk, given its higher prevalence and association with structural markers in bipolar patients, though longitudinal studies confirming its predictive value remain limited.^[15]

Developmental Mechanisms

Prenatal and Early Development

The Yakovlevian torque begins to emerge during gestation around 20 weeks, through differential growth patterns in the frontal and occipital regions of the brain, where the right frontal lobe expands anteriorly and the left occipital lobe protrudes posteriorly.^[16]^[17] This asymmetry arises as the cerebral hemispheres undergo a subtle anticlockwise rotation relative to the body's midline, becoming detectable via imaging modalities such as ultrasound and MRI in developing fetuses. Postnatally, the torque pattern continues to refine through ongoing brain growth into adolescence and young adulthood as cortical folding and hemispheric proportions mature.^[18] A key developmental framework explaining this torque is the axial twist model, which posits that the brain's asymmetry stems from an early embryonic torsion along the body axis, linking cerebral structure to broader orofacial and visceral lateralizations, such as the rightward looping of the heart tube around weeks 4-5 of gestation that influences neural patterning.^[19] This model suggests that the initial leftward body curl in the embryo establishes a foundational twist, with the head region rotating oppositely to the trunk, thereby contributing to the forward warping of the right hemisphere. At the cellular level, the torque's formation involves asymmetric cell migration within the neural tube, where progenitor cells proliferate and migrate preferentially to one side, guided by signaling gradients that establish left-right polarity. The sonic hedgehog (SHH) pathway plays a critical role in this process, as it regulates ventral midline signaling and asymmetric gene expression in the developing neuroepithelium, promoting differential regional expansion.^[20]^[21] Longitudinal imaging studies, including fetal MRI and computed tomography, have demonstrated progressive development of the torque from mid-gestation onward, with early variations in asymmetry magnitude correlating to later behavioral and cognitive lateralizations in childhood. For instance, fetal imaging reveals right frontal and left occipital protrusions as a normative feature of human brain ontogeny. Recent research also implicates biomechanical factors, such as asymmetries in dural venous sinuses, in shaping torque during prenatal development.^[1]

Genetic and Environmental Factors

Twin studies have estimated the heritability of Yakovlevian torque components at 30-56%, with higher values observed for specific features like temporal language area asymmetries in cohorts such as the Adolescent Brain Cognitive Development (ABCD) study (up to 56%) and the Human Connectome Project (up to 52%).^[4] These estimates indicate a moderate genetic contribution to torque formation, varying by brain region and developmental stage.^[4] The genetic architecture is polygenic, involving multiple loci identified through genome-wide association studies (GWAS). A meta-GWAS of over 24,000 individuals revealed 86 lead single nucleotide polymorphisms (SNPs) associated with brain torque features, though only two survived multiple-testing correction, highlighting the distributed nature of genetic influences on asymmetry.^[4] Among candidate genes, LRRTM1 on chromosome 2p12 has been implicated in brain asymmetry and handedness due to its maternal imprinting and role in neuronal connectivity; paternal inheritance of specific haplotypes increases asymmetry risks. This gene's expression patterns contribute to left-right differences in cortical organization, potentially influencing torque magnitude.^[22] Sex and handedness interact with these genetic factors to modulate torque expression. Males exhibit stronger typical torque patterns, including greater right-frontal petalia and increased variance in asymmetry measures, suggesting sex-dimorphic genetic effects that amplify hemispheric twisting.^[4] Right-handers display enhanced leftward frontal bending and left-occipital protrusion compared to non-right-handers, with these differences linked to heritable variance in torque components.^[4] A 2021 study mapping torque in large neuroimaging datasets confirmed these interactions, showing that sex and handedness account for significant variability in torque direction and strength beyond additive genetic effects. Environmental factors during prenatal development also shape Yakovlevian torque. Elevated prenatal testosterone exposure, as proposed in the Geschwind-Behan-Galaburda (GBG) theory, disrupts neural migration and cell proliferation, potentially altering torque direction by enhancing right-hemisphere forward warping relative to the left.^[2] This hormonal influence interacts with immune and neural crest cell development, leading to atypical asymmetries in affected individuals. Maternal stress may modulate brain asymmetry through epigenetic mechanisms.^[23] Evidence from rare conditions like situs inversus totalis underscores environmental and developmental links. A 2024 neuroimaging study of individuals with complete visceral reversal found that Yakovlevian torque direction correlates with intracranial transverse sinus volume asymmetry, independent of handedness or sex, suggesting shared prenatal pathways for visceral and cerebral laterality that can be disrupted by genetic or environmental anomalies.^[24] Gene-environment interactions further influence torque formation. For instance, phenome-wide scans associate brain torque with prenatal and early-life exposures, such as maternal tobacco smoking and alcohol consumption, which reduce torque magnitude through vascular and neurotoxic effects.^[4] These interactions highlight how environmental modulators can attenuate heritable torque patterns during critical developmental windows.^[4]

Evolutionary and Comparative Perspectives

Origins in Human Evolution

Fossil evidence for Yakovlevian torque in the hominid lineage derives primarily from endocranial casts of skulls, which preserve impressions of brain surface morphology, including petalia asymmetries indicative of the torque's characteristic right frontal and left occipital protrusions. These asymmetries are documented in some Homo erectus specimens dating to approximately 1.8 million years ago, such as endocasts from Dmanisi, Georgia, where patterns vary (e.g., right frontal/left occipital in D2282, reversed in D2280), alongside early signs of hemispheric distortion.^[25]^[26] Earlier australopith fossils, such as those of Australopithecus africanus, show no pronounced petalia or torque patterns comparable to Homo, with the Taung child (~2.8 million years ago) lacking significant asymmetries akin to modern humans.^[25] The evolutionary timeline of Yakovlevian torque aligns with key transitions in hominid brain reorganization, likely originating as a subtle asymmetry in late Pliocene hominins around 2-3 million years ago and becoming more marked with the onset of the genus Homo approximately 1.8-1.9 million years ago. A 2020 review highlights torque as a uniquely derived feature of the "human brain box," with a significant evolutionary rate shift occurring in the late Homo clade (including H. heidelbergensis, Neanderthals, and H. sapiens) during the Middle to Late Pleistocene, around 300,000 years ago, coinciding with expanded cranial capacities from ~600 cm³ in early Homo to over 1,200 cm³ in later forms.^[26]^[25] This progression reflects a broader trend of hemispheric specialization over 2-3 million years, correlating with a threefold increase in brain size across hominins.^[26] Evolutionary hypotheses posit Yakovlevian torque as an adaptation enhancing right-hemisphere visuospatial processing for navigation and tool manipulation, alongside left-hemisphere language-related functions, potentially tied to the cognitive demands of bipedalism and early stone tool use in Homo erectus. The torque's right frontal protrusion may have supported improved manual dexterity and spatial awareness during upright locomotion and Acheulean tool production, while the left occipital extension facilitated emerging linguistic capacities, contributing to social cooperation and cultural evolution.^[25]^[26] Its persistence and intensification in the Homo lineage underscore an adaptive value in promoting specialized neural processing amid rapid encephalization.^[26]

Occurrence in Non-Human Primates

Yakovlevian torque exhibits subtle manifestations in great apes, though far less pronounced than in humans. Early studies using endocranial casts reported right-frontal petalia in approximately 60-67% of chimpanzee and gorilla specimens, alongside left-occipital petalia in 50-60%, suggesting a partial ancestral pattern of asymmetry.^[27] However, more recent analyses employing MRI on larger samples of chimpanzees (n=78) found no statistically significant cerebral torque, with petalia patterns occurring randomly at about 31% prevalence and lacking directional bias in occipital shift or bending.^[6] These discrepancies highlight the variability in great ape brain organization, where any torque-like features do not consistently align across frontal and occipital regions as seen in humans.^[28] In Old World monkeys, torque displays greater variability, often linked to species-specific adaptations such as arboreal locomotion. For instance, studies on macaques have documented left-occipital asymmetries, though these are inconsistent and milder in magnitude compared to hominids, with petalia patterns appearing in a subset of individuals without the full anticlockwise twist characteristic of human brains.^[7] Such findings indicate that elements of torque may represent a broader primate trait, but one that is fragmented and not uniformly expressed across the order.^[6] New World primates generally show minimal or absent Yakovlevian torque, with few reports of reliable petalia or bending asymmetries in species like marmosets or capuchins.^[7] This paucity suggests that pronounced torque may have evolved later in the primate lineage, potentially tied to postural or ecological shifts in Old World ancestors. Methodological challenges complicate assessments of torque in non-human primates, including limited sample sizes for MRI scans and distortions in endocast reconstructions that can obscure subtle asymmetries.^[6] Recent decompositions of torque components via advanced imaging further indicate that humans exaggerate an ancestral pattern present in trace forms across primates, though direct phylogenetic comparisons remain constrained by these technical hurdles.^[29]

References

[1]
Brain (Yakovlevian) torque direction is associated with volume ...
May 30, 2024 · In the present study, we confirm general reversal of the brain torque and of posterior venous asymmetry in SIT-participants and observed a ...
[2]
Yakovlevian Torque: Something Old and Something New - PMC - NIH
This grand theory centered on the idea that intrauterine testosterone levels impact immune system development, ontogeny of neural crest cells, and a host of ...
[3]
(PDF) Cerebral torque is human specific and unrelated to brain size
The brain torque, also known as the Yakovlevian torque as it was first described in the late 1930s by Paul Ivan Yakovlev, a neuroanatomist at Harvard ...
[4]
Mapping cortical brain asymmetry in 17,141 healthy ... - PNAS
May 15, 2018 · One aspect of structural asymmetry in the human brain is “Yakovlevian torque,” an overall hemispheric twist giving rise to the frontal and ...
[5]
Mapping Complex Brain Torque Components and Their Genetic ...
Apr 15, 2023 · The most prominent structural asymmetry is an overall hemispheric twist of the brain, known as the Yakovlevian torque (24).
[6]
Cerebral torque is human specific and unrelated to brain size - PMC
Jan 11, 2019 · Abstract. The term “cerebral torque” refers to opposing right–left asymmetries of frontal and parieto-occipital regions.Missing: Paul 1930s
[7]
[PDF] MAPPING BRAIN ASYMMETRY
A twisting effect is also observed, known as Yakovlevian torque, in which structures surrounding the right Sylvian fissure are 'torqued forward' relative to ...
[8]
Reliability of structural MRI measurements: The effects of scan ... - NIH
We examined the effect of repetition, reposition, head tilt, time between scans, MRI sequence and scanner on reliability of structural brain measurements.
[9]
CT Brain Prescriptions in Talairach Space: A New Clinical Standard
Feb 1, 2004 · Variability in head positioning and prescribed techniques for MR imaging and CT may yield significant intra- and intersubject image variance ...
[10]
https://doi.org/10.1017/thg.2012.13
[11]
https://doi.org/10.1016/j.biopsych.2021.11.002
[12]
https://doi.org/10.1016/j.neuroimage.2005.10.013
[13]
https://pmc.ncbi.nlm.nih.gov/articles/PMC5537737/
[14]
https://pubmed.ncbi.nlm.nih.gov/14567937/
[15]
[PDF] Folding Dynamics in the Very Preterm Brain
Jun 29, 2022 · Yakovlevian torque (Hou et al., 2019; frontal forward warping of the ... soon as 14 to 16 weeks of gestational age (w GA), while the first sulci.
[16]
Structural asymmetries of perisylvian regions in the preterm newborn
... 14 weeks of gestation onward. The potential influence of underlying ... Our analysis confirms previously identified hemispheric asymmetries (Yakovlevian torque, ...<|control11|><|separator|>
[17]
Hemispheric asymmetry in cortical thinning reflects intrinsic ... - PNAS
Oct 13, 2023 · The typical spatial pattern of hemispheric asymmetry in thickness of the human cerebral cortex emerges during postnatal development (4–6).Missing: stabilization | Show results with:stabilization<|control11|><|separator|>
[18]
Opposite asymmetries of face and trunk and of kissing and hugging ...
Jun 7, 2019 · According to the Axial Twist Hypothesis (ATH) the rostral head and the rest of the body are twisted with respect to each other to form a ...
[19]
Axial twist theory - Wikipedia
Developmental phases are (from top to bottom): (1) the embryo turns on its left side; (2) the anterior head grows in the same direction, but the rest of the ...
[20]
A highlight on Sonic hedgehog pathway
Mar 20, 2018 · Hedgehog (Hh) signaling pathway plays an essential role during vertebrate embryonic development and tumorigenesis.
[21]
Atypical Brain Asymmetry in Human Situs Inversus: Gut Feeling or ...
... torque is generally reversed than the typical human population bias. The cerebral or “Yakovlevian” torque is a gross anatomical and morphologically complex ...
[22]
An exploratory study of the relationship between brain torque and ...
This 'twisting' structural configuration is consistent with the Yaklovevian torque, or brain torque, a pattern of tissue asymmetry characterized by increased ...Missing: 1930s 1960s
[23]
https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2019.00982/full
[24]
Building an Asymmetrical Brain: The Molecular Perspective - PMC
The first visceral asymmetry is detected when the heart, initially a straight tube, starts to loop at the end of 5 gestational weeks and occupies its typical ...
[25]
Building an Asymmetrical Brain: The Molecular Perspective - Frontiers
Apr 29, 2019 · Moreover, the typical counter-clockwise bending of the brain (Yakovlevian torque) ... Prenatal maternal stress predicts methylation of genes ...
[26]
Brain (Yakovlevian) torque direction is associated with volume ...
May 30, 2024 · Transverse sinus volume was significantly correlated with several torque measures, such that the smaller transverse sinus was associated with a larger ...
[27]
Birth weight predicts brain development - Department of Psychology
Feb 20, 2013 · The study shows that birth weight affects the extent of the cerebral cortex and the brains total volume in later childhood and adolescence years ...Stabile Affect · Development Of Illness · Early Influence<|control11|><|separator|>
[28]
Evolution, development, and plasticity of the human brain
Oct 30, 2013 · Neuroanatomical, molecular, and paleontological evidence is examined in light of human brain evolution.
[29]
From Smart Apes to Human Brain Boxes. A Uniquely ... - Frontiers
Jul 13, 2020 · Although the Yakovlevian torque is well evident in these species and levels of brain asymmetry are correlated to changes in brain shape, further ...<|separator|>
[30]
MORPHOLOGICAL CEREBRAL ASYMMETRIES OF MODERN MAN ...
Measurements of cerebral and cerebellar surfaces, comparative studies of the surfaces of endocranial casts of man, prehistoric men, and anthropoid apes.
[31]
Human torque is not present in chimpanzee brain - ScienceDirect
Jan 15, 2018 · ... Yakovlev and Rakic (1966) in post-mortem brain. The Torque refers to an anticlockwise twist of the brain about the ventral-dorsal axis ...Missing: original | Show results with:original
[32]
Mapping Complex Brain Torque Components and Their Genetic and Phenomic Architecture in 24,112 healthy individuals
**Summary of Yakovlevian Torque in Non-Human Primates and Related Findings:**