Bayesian probability
Bayesian probability is an interpretation of the concept of probability in which probabilities represent degrees of belief or subjective confidence in the occurrence of an event or the truth of a hypothesis, rather than objective long-run frequencies, and these beliefs are rationally updated using Bayes' theorem in response to new evidence.[1][2][3] The foundational principle, Bayes' theorem, provides a mathematical framework for this updating process, expressed asP(H|E) = \frac{P(E|H) \cdot P(H)}{P(E)},
where P(H|E) is the posterior probability of hypothesis H given evidence E, P(E|H) is the likelihood of observing E if H is true, P(H) is the prior probability of H, and P(E) is the marginal probability of E.[1][4] This theorem, derived from the definition of conditional probability, allows for the incorporation of prior knowledge or beliefs into statistical inference, treating unknown parameters as random variables described by probability distributions.[5][2] Historically, the ideas trace back to the 18th century, when English mathematician and Presbyterian minister Thomas Bayes (c. 1701–1761) developed the theorem as part of an effort to quantify inductive reasoning, possibly motivated by the philosophical arguments of David Hume on causation and evidence.[6] Bayes' work remained unpublished during his lifetime and was edited and presented to the Royal Society by his colleague Richard Price in 1763, under the title "An Essay towards solving a Problem in the Doctrine of Chances."[1] The approach gained prominence in the 20th century through advocates like Harold Jeffreys and Bruno de Finetti, who formalized subjective probability interpretations, though it faced criticism for perceived subjectivity until computational advances revived its use.[7][1] In contrast to frequentist statistics, which views probabilities as limits of relative frequencies in repeated experiments and estimates parameters as fixed unknowns, Bayesian methods enable direct probabilistic statements about parameters, such as the probability that a parameter exceeds a certain value, by integrating over the posterior distribution.[5][8] This framework is particularly powerful in handling uncertainty, small sample sizes, and hierarchical models, where priors can encode expert knowledge or regularization.[4][9] Bayesian probability has broad applications across fields, including statistical inference for parameter estimation and hypothesis testing, machine learning algorithms like Bayesian networks and Gaussian processes for prediction and classification, medical diagnostics to update disease probabilities based on test results, and decision-making under uncertainty in economics and policy analysis.[10][11][12] Notable modern uses include spam detection in email filters, adaptive clinical trials that adjust sample sizes dynamically, and probabilistic modeling in artificial intelligence to manage complex, high-dimensional data.[10][9][13]
Foundations of Bayesian Probability
Definition and Interpretation
Bayesian probability interprets probability as a measure of the degree of belief in a proposition or hypothesis, rather than as a long-run relative frequency of events in repeated trials.[14] This subjective view allows probabilities to represent personal or epistemic uncertainty about unknown quantities, such as parameters in a statistical model, and enables the incorporation of prior knowledge or beliefs before observing data.[15] In contrast, the frequentist interpretation treats probability as an objective property defined by the limiting frequency of an event occurring in an infinite sequence of identical trials under fixed conditions.[16] For instance, in estimating the bias of a coin from a small number of flips—say, observing 3 heads in 5 flips—a frequentist approach would compute a point estimate of the heads probability (e.g., 0.6) along with a confidence interval based on hypothetical repeated sampling, without assigning probability to the parameter itself.[17] A Bayesian approach, however, would update an initial belief about the bias using the observed data, yielding a full probability distribution over possible bias values that quantifies uncertainty directly.[18] Central to this framework are several key concepts: the prior distribution, which encodes initial beliefs about an unknown parameter before seeing data; the likelihood, which measures how well the observed data support different parameter values; the posterior distribution, representing updated beliefs after incorporating the data; and the evidence (or marginal likelihood), which is the probability of the data averaged over all possible parameter values and serves as a normalizing factor.[5] These elements facilitate belief updating, where Bayes' theorem provides the mathematical mechanism for combining the prior and likelihood to obtain the posterior (detailed in subsequent sections).[19] The term "Bayesian" derives from the 18th-century work of Thomas Bayes, whose essay laid foundational ideas for inverse probability, though the modern approach encompasses broader developments in statistical inference. A simple illustration of belief updating occurs when assessing the likelihood of rain: an individual might start with a 30% prior belief based on seasonal patterns, then observe dark clouds and a weather report, adjusting their belief to 80% as the new evidence strengthens the case for rain without requiring repeated observations.[15] This process highlights how Bayesian probability accommodates incomplete or finite evidence, providing a coherent way to revise uncertainties in real-world scenarios.[5]Bayes' Theorem
Bayes' theorem provides the mathematical foundation for updating probabilities based on new evidence in Bayesian inference. It states that the posterior probability of an event A given evidence B, denoted P(A|B), is equal to the likelihood of the evidence given A, P(B|A), times the prior probability of A, P(A), divided by the marginal probability of the evidence, P(B): P(A|B) = \frac{P(B|A) P(A)}{P(B)} Here, P(A) represents the prior belief about A before observing B, P(B|A) is the likelihood measuring how well B supports A, and P(B) normalizes the result to ensure probabilities sum to 1.[20] The theorem derives directly from the axioms of conditional probability. The joint probability of A and B can be expressed as P(A \cap B) = P(A|B) P(B) or equivalently P(A \cap B) = P(B|A) P(A). Equating these forms yields P(A|B) P(B) = P(B|A) P(A), and solving for P(A|B) gives the theorem.[20] An equivalent formulation uses odds ratios, which express relative probabilities. The posterior odds of A versus its complement \neg A given B equal the prior odds times the likelihood ratio: \frac{P(A|B)}{P(\neg A|B)} = \frac{P(B|A)}{P(B|\neg A)} \times \frac{P(A)}{P(\neg A)}. This form highlights how evidence multiplies the initial odds by a factor quantifying the evidence's evidential value.[21] For continuous parameters, P(B) is the marginal likelihood obtained by integrating over all possible values of A: P(B) = \int P(B|A) P(A) \, dA. This integral accounts for the total probability of the evidence across the prior distribution.[22] A common application is in diagnostic testing, where Bayes' theorem computes the probability of disease given a positive test result. Suppose a disease has a prior prevalence of 1% (P(D) = 0.01), and a test has 99% sensitivity (P(+|D) = 0.99) and 99% specificity (P(-|\neg D) = 0.99, so P(+|\neg D) = 0.01). The posterior probability of disease given a positive test is P(D|+) = \frac{0.99 \times 0.01}{0.99 \times 0.01 + 0.01 \times 0.99} \approx 0.50, showing that even with high test accuracy, the low prevalence halves the odds of true disease.[23]Philosophical Perspectives
Subjective Bayesianism
Subjective Bayesianism views probabilities as personal degrees of belief, or credences, that reflect an individual's subjective assessment of uncertainty rather than objective frequencies or long-run tendencies. These credences are coherent if they satisfy the axioms of probability theory and are updated rationally using Bayes' theorem when new evidence becomes available. This approach, pioneered by Bruno de Finetti, emphasizes that probability is inherently subjective, with each person's priors representing their unique state of knowledge or opinion prior to observing data.[24][25] Coherence in subjective Bayesianism requires adherence to key probability axioms to ensure consistency in one's beliefs and avoid opportunities for sure loss in betting scenarios. Specifically, credences must be non-negative (no belief can have negative probability), normalized (certainty in a tautology is 1, and in a contradiction is 0), and additive (the credence in a disjunction of mutually exclusive events equals the sum of their individual credences). These axioms, as articulated by de Finetti, form the foundation for rational belief structures, where violations lead to incoherence and potential Dutch book arguments against the agent. By maintaining coherence, subjective Bayesians ensure their degrees of belief are logically consistent and amenable to probabilistic reasoning.[24][26] An illustrative example of subjective Bayesian updating occurs in everyday decision-making, such as predicting weather. Suppose an individual initially holds a credence of 0.4 that it will rain tomorrow, based on seasonal patterns and personal experience (their prior). Upon observing a detailed forecast indicating high humidity and wind patterns favorable for rain, they incorporate this evidence via Bayes' theorem to revise their credence upward to 0.8 (the posterior). This process demonstrates how subjective beliefs evolve dynamically with incoming information, allowing for personalized yet rational adjustments without relying on objective frequencies.[24] The implications of subjective Bayesianism for rationality position Bayesian updating as the normative ideal for belief revision, prescribing that individuals should proportion their credences to the evidence to achieve coherent and evidence-responsive opinions. This framework argues that any rational agent, regardless of their starting priors, will converge toward truth over time through repeated updating, provided the evidence is reliable. However, critics argue that over-reliance on personal priors can foster dogmatism, as strongly held initial beliefs may require overwhelming contrary evidence to shift significantly, potentially trapping individuals in irrational entrenchment even when faced with compelling data. For instance, a dogmatic prior close to 1 or 0 can render posterior beliefs nearly unchanged, undermining the method's responsiveness to reality.[24][27]Objective Bayesianism
Objective Bayesianism seeks to establish priors through formal principles that promote intersubjectivity and minimize personal bias, deriving probabilities from logical rules or informational constraints rather than individual beliefs. This approach contrasts with subjective Bayesianism by emphasizing methods that different rational agents would agree upon, such as invariance under transformations or maximization of uncertainty. It positions itself as a framework for objective inference within the Bayesian paradigm, often justified by requirements like consistency across parameterizations.[24] A core method in objective Bayesianism is the principle of indifference, formulated by Pierre-Simon Laplace as the principle of insufficient reason. This principle dictates that, in the absence of distinguishing evidence, equal probabilities should be assigned to all mutually exclusive and exhaustive hypotheses. For discrete parameters, it results in a uniform prior distribution. Laplace applied this to sequential predictions via the rule of succession: after observing s successes in n trials of a Bernoulli process, the predictive probability of success on the next trial is \frac{s+1}{n+2}, reflecting an initial uniform prior over the success probability updated by data. This approach aims for neutrality but has been critiqued for ambiguity in continuous cases.[24] The maximum entropy principle, advanced by Edwin T. Jaynes, provides a more general tool for constructing objective priors by selecting the distribution that maximizes Shannon entropy subject to constraints encoding available information. Entropy, defined as H(p) = -\sum p_i \log p_i for discrete cases or the integral analog for continuous, measures uncertainty; maximizing it yields the least informative prior consistent with the constraints. For example, with no constraints beyond normalization and a fixed mean, the maximum entropy prior is exponential; with a fixed variance, it is Gaussian. Jaynes argued this principle aligns with scientific inference by avoiding unfounded assumptions. Jeffreys priors exemplify objective methods through invariance considerations. Proposed by Harold Jeffreys, these priors are proportional to the square root of the determinant of the Fisher information matrix, ensuring the posterior is invariant under reparameterization. For scale parameters \theta > 0, such as variance in location-scale models, the Jeffreys prior simplifies to p(\theta) \propto 1/\theta: p(\theta) \propto \frac{1}{\theta}, \quad \theta > 0. This form arises because the Fisher information for scale parameters scales with $1/\theta^2, leading to a prior that treats logarithmic scales uniformly. In inference for a normal distribution's standard deviation, this prior yields posteriors that are scale-invariant, facilitating consistent conclusions across units.[12] Objective Bayesianism serves as a middle ground between pure subjectivism and frequentist objectivity, retaining the subjective interpretation of probability while imposing invariance and minimality requirements on priors to achieve consensus. Proponents like James O. Berger argue that such rules, including reference priors (an extension of Jeffreys), balance flexibility with rigor, allowing Bayesian methods to approximate frequentist properties in large samples. This hybrid nature enables applications in complex statistical modeling where subjective elicitation is impractical.[12] Despite these strengths, objective Bayesian methods can produce counterintuitive results, particularly in complex models. The principle of indifference may yield paradoxes, such as differing probabilities from alternative event partitions in geometric problems. Maximum entropy priors can be improper or lead to posteriors that overweight tails in high dimensions, while Jeffreys priors sometimes fail to integrate to finite values in multiparameter settings, complicating normalization. These issues highlight challenges in ensuring priors remain noninformative across intricate structures.[24]Historical Development
Precursors and Early Formulations
The foundations of probabilistic reasoning that would later underpin Bayesian probability emerged in the 17th century through efforts to quantify uncertainty in games of chance. Blaise Pascal and Christiaan Huygens developed early concepts of expected value and fair division in interrupted games, such as the "problem of points," where Pascal's correspondence with Pierre de Fermat in 1654 laid groundwork for calculating probabilities based on combinatorial analysis.[28] Huygens extended this in his 1657 treatise De ratiociniis in ludo aleae, formalizing the concept of mathematical expectation as the average outcome over possible events, providing a rigorous framework for decision-making under uncertainty that influenced subsequent probability theory.[29] These works shifted probability from qualitative judgment to quantitative computation, setting the stage for inverse inference. Jacob Bernoulli's Ars Conjectandi (1713) advanced this foundation with the first proof of the law of large numbers, demonstrating that the relative frequency of an event converges to its probability as trials increase, thereby linking empirical observation to theoretical probability in a way that resonated with later Bayesian updating of beliefs based on evidence.[30] Bernoulli viewed probability as a degree of certainty, incorporating subjective elements into his analysis of binomial trials, which prefigured Bayesian approaches to inference by emphasizing how repeated observations refine estimates of underlying chances.[31] The explicit formulation of inverse probability appeared posthumously in Thomas Bayes's 1763 essay, "An Essay towards Solving a Problem in the Doctrine of Chances," edited and submitted to the Royal Society by Richard Price.[32] Bayes addressed the challenge of inferring the probability of a cause from observed effects, framing it as a method to update prior assessments of an event's likelihood based on new data, which Price recognized as a novel tool for inductive reasoning in natural philosophy.[33] Price's editorial role was pivotal, as he not only published the work but also highlighted its potential for applications beyond chance, ensuring its dissemination among contemporary mathematicians. Pierre-Simon Laplace built directly on Bayes's ideas in his 1774 Mémoire sur la probabilité des causes par les événements, where he generalized inverse probability to determine the likelihood of competing hypotheses given observed data, applying it to problems in physics and astronomy such as predicting planetary perturbations.[34] Over the following decades, Laplace refined these concepts in works like Théorie analytique des probabilités (1812), introducing the rule of succession—a formula for estimating the probability of future successes after a sequence of observed ones, assuming uniform priors—which he used to assess astronomical stability, such as the probability of the solar system's endurance.[35] These contributions transformed Bayes's tentative essay into a systematic methodology for scientific inference, emphasizing the role of prior probabilities in updating beliefs with evidence.Revival and Modern Advancements
The revival of Bayesian probability in the mid-20th century began with the development of subjective probability frameworks by Frank Ramsey and Bruno de Finetti. In his 1926 essay "Truth and Probability," Ramsey laid foundational ideas for interpreting probabilities as degrees of belief, measurable through betting behavior, which gained renewed attention in the 1930s and 1940s amid debates on statistical foundations.[36] Independently, de Finetti advanced subjective probability in the 1930s, notably through his 1937 work La prévision: ses lois logiques, ses sources subjectives, arguing that all probabilities are inherently personal and coherence requires adherence to Dutch book avoidance, influencing Bayesian thought through the 1950s.[37] Leonard J. Savage's 1954 book The Foundations of Statistics further solidified this resurgence by axiomatizing subjective probability within a decision-theoretic framework, linking Bayesian updating to expected utility maximization and providing a normative basis for personal probabilities in statistical inference.[38] This work bridged probability and utility theory, encouraging the application of Bayesian methods to practical problems in economics and decision-making during the post-war era. From the 1960s onward, computational advancements enabled the widespread adoption of Bayesian techniques, particularly through Markov chain Monte Carlo (MCMC) methods. The Metropolis-Hastings algorithm, introduced in 1953 but largely popularized in the 1990s for Bayesian computation, allowed sampling from complex posterior distributions, revolutionizing inference in high-dimensional spaces.[39] Key figures like Dennis V. Lindley promoted Bayesian statistics through his advocacy for decision-theoretic approaches and editorial roles, such as on the Journal of the Royal Statistical Society Series B, which emphasized Bayesian perspectives.[40] George E. P. Box contributed seminal work on Bayesian robustness and model building, including transformations and hierarchical structures in time series analysis during the 1960s and 1970s.[41] Andrew Gelman advanced modern Bayesian practice in the late 20th and early 21st centuries, co-authoring influential texts like Bayesian Data Analysis (1995, updated 2013) that integrated computation with hierarchical modeling.[42] Post-2000 developments have integrated Bayesian methods into machine learning, hierarchical models, and big data analytics, addressing scalability and uncertainty quantification. Bayesian hierarchical models, which pool information across levels to improve estimates in varied datasets, have become standard for applications like epidemiology and social sciences.[43] In machine learning, Bayesian approaches enhance neural networks and reinforcement learning by incorporating priors for regularization and uncertainty, as seen in scalable inference techniques for large-scale data.[44] The 2020s have witnessed accelerated growth in Bayesian applications to artificial intelligence, driven by needs for reliable probabilistic predictions in areas like autonomous systems and federated learning, amid challenges like computational efficiency and prior elicitation.[45]Justifications for Bayesian Inference
Axiomatic Foundations
Bayesian probability aligns with the foundational axioms of probability theory, providing a rigorous mathematical justification for its use in inference. The standard axioms, formulated by Andrey Kolmogorov in 1933, define probability as a measure on a sample space \Omega: non-negativity requires $0 \leq P(E) \leq 1 for any event E \subseteq \Omega, normalization states P(\Omega) = 1, and countable additivity holds that for a countable collection of pairwise disjoint events E_i, P\left(\bigcup_i E_i\right) = \sum_i P(E_i).[46] These axioms ensure that probability functions are consistent and behave like measures, forming the basis for all probabilistic reasoning. In the Bayesian framework, probabilities represent degrees of belief that satisfy these axioms, interpreted as coherent previsions—fair prices for gambles over uncertain outcomes that avoid arbitrage opportunities. Bruno de Finetti emphasized this coherence, showing that subjective probabilities must conform to Kolmogorov's axioms to maintain logical consistency in prevision assessments.[47] Thus, Bayesian updating preserves additivity and other properties, ensuring that posterior beliefs remain valid probability measures. The extension to conditional probabilities, central to Bayesian inference, follows from Cox's theorem, which derives the rules of probability—including Bayes' theorem—from qualitative desiderata such as transitivity of reasoning (if A implies B and B implies C, then A implies C) and dominance (a conclusion supported by more evidence cannot be less probable than one supported by less). Richard T. Cox demonstrated that any calculus of inference satisfying these conditions is isomorphic to the standard probability calculus.[48] To illustrate, consider a non-Bayesian updating rule where an agent overweights new evidence without fully adjusting for prior structure; for instance, in a setting with multiple hypotheses, such a rule can lead to posterior beliefs that violate additivity over disjoint events, as the updated probabilities fail to sum correctly for unions.[49] This incoherence highlights why adherence to Bayesian rules is necessary for maintaining the axioms. However, the axioms permit non-uniqueness in infinite sample spaces, where multiple probability measures can satisfy the conditions on the same \sigma-algebra, complicating the representation of beliefs without additional structure like regularity assumptions.[46]Dutch Book Arguments
A Dutch book refers to a collection of bets structured such that the bettor incurs a guaranteed loss irrespective of the actual outcome of the underlying events. This concept, originating in the work of Bruno de Finetti, serves as a pragmatic tool to demonstrate the necessity of coherence in subjective probabilities, where degrees of belief are equated with fair betting quotients. In essence, if an agent's stated probabilities permit such a set of wagers, their beliefs are deemed incoherent, as they expose the agent to sure financial detriment without any compensating gain.[50] In his seminal 1937 paper, de Finetti established a foundational theorem asserting that any assignment of probabilities failing finite additivity—meaning the probability of a disjoint union does not equal the sum of individual probabilities—admits a Dutch book. Specifically, de Finetti demonstrated that non-additive previsions (betting quotients) over a finite partition of events allow a bookmaker to construct a sequence of acceptable bets that yields a positive net gain for the bookmaker regardless of which event occurs. This theorem underpins the subjective Bayesian view by linking probabilistic coherence directly to avoidance of sure loss in betting scenarios.[51] The Dutch book argument extends naturally to conditional probabilities and betting, reinforcing the requirement for Bayesian updating. de Finetti showed that coherence under conditional wagers—bets resolved only if a conditioning event occurs—necessitates that conditional probabilities satisfy the ratio P(A|B) = P(A ∩ B)/P(B), thereby ensuring that revisions of beliefs upon new evidence do not introduce vulnerabilities to Dutch books. Violations of this conditional coherence, such as inconsistent updating rules, permit a bookmaker to exploit the agent through a series of conditional bets that guarantee loss after the conditioning event transpires.[52] A illustrative example arises in a horse race with mutually exclusive outcomes. Suppose a bettor assigns probabilities such that the sum over all horses exceeds 1, say P(Horse A wins) = 0.6 and P(Horse B wins) = 0.6 for a two-horse race. A bookmaker can then accept bets from the bettor on both horses at these odds (equivalent to paying out $1 for a $0.6 stake if the horse wins) while simultaneously offering a bet against the race occurring (or exploiting the overestimation). By wagering appropriately on each, the bookmaker secures a net profit: if A wins, the bookmaker pays $1 on A's bet but collects from the excess; the imbalance ensures overall gain exceeding stakes across outcomes. This arbitrage-like loss for the bettor highlights how additive violations enable exploitation.[52] Extensions of de Finetti's argument to continuous probability spaces involve approximating infinite partitions with finite ones, where coherence still demands avoidance of Dutch books through integral constraints akin to additivity. However, such extensions often rely on limits of finite cases and face challenges in rigorously constructing sure-loss bets without additional regularity conditions.[53] Critiques of the Dutch book framework commonly point to its implicit assumption of risk neutrality, as the argument presumes agents accept small bets at fair odds without utility curvature, potentially failing for risk-averse or risk-seeking individuals who might rationally decline such wagers to avoid variance.[54] Despite these limitations, the argument remains a cornerstone for justifying probabilistic coherence in Bayesian inference.Decision-Theoretic Justifications
Decision-theoretic justifications for Bayesian probability emphasize its role in rational decision-making under uncertainty, where choices are evaluated based on expected utility maximization. In this framework, subjective probabilities serve as inputs to utility functions, enabling agents to select actions that optimize outcomes according to their preferences.[55] A foundational contribution comes from Leonard J. Savage's axiomatic system in The Foundations of Statistics (1954), which derives subjective expected utility from a set of postulates including completeness (every pair of acts can be compared), transitivity (preferences are consistent across comparisons), and continuity (preferences allow for probabilistic mixtures). These axioms imply that rational agents represent beliefs via subjective probabilities and evaluate decisions by maximizing expected utility, providing a normative basis for Bayesian methods in uncertain environments.[56] Bayesian updating aligns with this framework by offering an optimal strategy for minimizing expected loss in sequential decisions. Upon receiving new evidence, the posterior distribution minimizes the posterior expected loss for actions, ensuring that decisions incorporate all available information to achieve the lowest anticipated risk.[57] For instance, in medical decision-making, a physician might use Bayesian updating to assess the posterior probability of a disease given test results and prior prevalence, then select a treatment that minimizes expected loss—such as weighing the risks of false positives against treatment side effects to avoid unnecessary interventions.[58] This approach connects to Abraham Wald's statistical decision theory, outlined in Statistical Decision Functions (1950), where Bayes rules are shown to be admissible, meaning no other rule can perform better in all states without performing worse in some, thus justifying Bayesian procedures as minimally suboptimal in inference.[59][60] Critiques of these justifications highlight the sensitivity of Bayesian decisions to prior specifications, particularly in high-stakes contexts where differing priors can lead to substantially varied expected utilities and potentially suboptimal choices if priors are misspecified.[61]Prior Distributions
Eliciting Personal Priors
Eliciting personal priors involves structured processes to translate an individual's subjective beliefs into formal probability distributions for Bayesian analysis, rooted in the subjective Bayesianism paradigm where priors reflect personal degrees of belief.[62] Practical methods for direct elicitation include questionnaires that prompt experts to specify quantiles or percentiles of their beliefs about parameters, such as estimating the 25th, 50th, and 75th percentiles for a distribution's shape.00175-9/fulltext) Imagining scenarios, known as predictive elicitation, asks individuals to forecast outcomes under hypothetical conditions to infer prior distributions indirectly, reducing direct focus on parameter values.[63] Betting analogies, like the roulette method, simulate wagering on outcomes to reveal implicit probabilities, helping to quantify beliefs through relative odds.[64] In assigning priors, individuals must recognize encoding biases such as optimism or pessimism, where overly positive or negative expectations can skew distributions toward extreme values, and anchoring effects, where initial suggestions unduly influence subsequent judgments.00175-9/fulltext)[65] To mitigate these, elicitation protocols often incorporate clear instructions, randomized question orders, and feedback to encourage balanced assessments.00175-9/fulltext) A representative example occurs in clinical trials, where the Delphi method elicits priors for treatment efficacy parameters by iteratively surveying experts anonymously, providing aggregated feedback after each round to converge on a consensus distribution, such as for a drug's response rate.[66] Personal priors are updated iteratively with incoming data through Bayesian inference, where the posterior from one stage becomes the prior for the next, allowing beliefs to evolve sequentially as evidence accumulates.[67] Challenges in elicitation include interpersonal variability, where experts in the same domain may produce substantially different prior distributions due to diverse experiences, leading to divergent posterior inferences.[68] Anchoring effects exacerbate this by causing reliance on initial elicited values across individuals, complicating aggregation into group priors.[64]Objective Methods for Prior Construction
Objective methods for prior construction in Bayesian statistics aim to select prior distributions that are free from subjective personal beliefs, instead relying on formal principles to achieve desirable inferential properties such as invariance, optimality in information gain, or frequentist coverage guarantees. These methods emerged as a response to the challenges of eliciting informative priors, particularly in complex models where expert opinion may be unreliable or unavailable. By focusing on the model's structure and sampling properties, objective priors facilitate reproducible and objective Bayesian analyses.[69] One foundational approach is the Jeffreys prior, which derives a non-informative prior proportional to the square root of the determinant of the Fisher information matrix. Formally, for a parameter \theta, the prior is given by \pi(\theta) \propto \sqrt{\det \mathcal{I}(\theta)}, where \mathcal{I}(\theta) is the expected Fisher information matrix, \mathcal{I}(\theta) = - \mathbb{E} \left[ \frac{\partial^2}{\partial \theta \partial \theta^T} \log f(y|\theta) \right]. This construction ensures invariance under reparameterization, meaning the prior transforms appropriately when the parameter is nonlinearly changed, preserving the non-informative nature. Harold Jeffreys introduced this rule in his seminal work to address the arbitrariness of uniform priors in multidimensional settings.[70] The Jeffreys prior often yields posteriors with good frequentist properties, such as consistent estimation, but can be improper (integrating to infinity) and may lead to paradoxes in certain hierarchical models.[71] A refinement for multiparameter problems is the reference prior, which seeks to maximize the expected missing information about the parameters of interest, measured via Kullback-Leibler divergence between the prior and posterior. Introduced by José M. Bernardo, the method involves a sequential algorithm: for parameters \theta = (\phi, \psi) where \phi is of primary interest, the reference prior is constructed by first deriving a conditional prior for nuisance parameters \psi given \phi (often a Jeffreys-like prior in compact sets), then integrating to obtain the marginal prior for \phi that maximizes \lim_{c \to \infty} \mathbb{E}_{\theta} \left[ D_{KL} (\pi(\cdot | y) || \pi(\cdot)) \right], where D_{KL} is the Kullback-Leibler divergence and the expectation is over the model. This approach produces priors that are asymptotically optimal for inference on \phi, independent of the choice of \psi, and often coincides with the Jeffreys prior in one dimension but differs in higher dimensions to avoid over-emphasis on nuisance parameters. Berger and Bernardo extended the framework to provide theoretical justifications and algorithms for computation, emphasizing its use in producing posteriors with strong frequentist validity.[72][73] Probability matching priors represent another class, designed to ensure that Bayesian credible intervals achieve target frequentist coverage probabilities asymptotically. These priors are constructed such that the posterior quantile-based intervals match the nominal coverage of frequentist confidence intervals, often satisfying \pi(\theta) \propto | \mathcal{I}(\theta) |^{1/2} \cdot J(\theta), where J(\theta) is a adjustment factor derived from higher-order terms in the expansion of the coverage probability. Pioneered by Welch and Peers, this method prioritizes inferential consistency between Bayesian and frequentist paradigms, making it particularly useful in hypothesis testing and interval estimation. In many cases, the first-order matching prior is the Jeffreys prior, but higher-order versions provide better finite-sample performance.[74] Datta and Mukerjee formalized the conditions for exact matching in multiparameter settings, highlighting applications in regression and survival analysis.[75] These methods are not without limitations; for instance, reference priors can depend on the grouping of parameters, and matching priors may require case-specific derivations. Nonetheless, they form the cornerstone of objective Bayesian practice, with software implementations available in packages like R'sPriorGen for automated construction. Ongoing research integrates these with empirical Bayes techniques for robustness in high-dimensional data.[76]