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Descending aorta

The descending aorta is the longest portion of the aorta, the body's principal artery, extending from the aortic arch downward through the thorax and abdomen to deliver oxygen-rich blood to the lower body.^[1] It begins immediately distal to the origin of the left subclavian artery and terminates at the level of the fourth lumbar vertebra, where it bifurcates into the common iliac arteries.^[2] This segment is divided into the descending thoracic aorta, which courses through the posterior mediastinum to the left of the vertebral column and passes through the aortic hiatus at the twelfth thoracic vertebra, and the descending abdominal aorta, which continues inferiorly along the anterior aspect of the spine.^[2]^[1] Anatomically, the descending aorta features a typical arterial wall structure with three layers: the tunica intima (innermost endothelial lining), tunica media (smooth muscle and elastic fibers for elasticity and contractility), and tunica adventitia (outer connective tissue).^[1] Its diameter varies, averaging less than 1.6 cm per square meter of body surface area in the thoracic portion and about 2 cm in the abdominal portion, though it can dilate pathologically.^[1] The thoracic segment gives rise to visceral branches such as the bronchial, esophageal, and pericardial arteries, as well as parietal branches including nine pairs of posterior intercostal arteries, subcostal arteries, and superior phrenic arteries.^[2] In the abdomen, major branches include the celiac trunk (supplying foregut derivatives like the stomach and liver), superior and inferior mesenteric arteries (for midgut and hindgut), paired renal and gonadal arteries, and lumbar arteries.^[2] These branches ensure oxygenated blood reaches critical organs, including the lungs, esophagus, gastrointestinal tract, kidneys, and lower limbs.^[1]^[2] Embryologically, the descending aorta develops during the third week of gestation from the fusion of dorsal and ventral aortic segments, contributing to the formation of the definitive aortic arch on the left side.^[2] Clinically, the descending aorta is prone to conditions such as aneurysms (localized dilations exceeding 3 cm in the abdomen), dissections (tears in the intimal layer allowing blood to enter the media), and coarctation (congenital narrowing), often linked to risk factors like hypertension, smoking, and hyperlipidemia.^[2]^[1] These pathologies can be asymptomatic until rupture, posing life-threatening risks that necessitate imaging like CT angiography for diagnosis and interventions such as endovascular repair.^[1]

Overview

Definition and divisions

The descending aorta is the segment of the aorta that extends downward from the aortic arch, beginning at the level of the fourth thoracic vertebra (T4), through the posterior mediastinum and retroperitoneal space, until it bifurcates into the left and right common iliac arteries at the level of the fourth lumbar vertebra (L4); it transports oxygenated blood from the left ventricle to the trunk and lower extremities.^[2]^[1] This portion of the aorta is divided into the thoracic descending aorta and the abdominal descending aorta, corresponding to its passage through the thorax and abdomen, respectively. The thoracic descending aorta spans from T4 to the aortic hiatus of the diaphragm at T12 and measures approximately 20 cm in length, while the abdominal descending aorta extends from T12 to L4 and is about 13 cm long.^[3]^[4] The descending aorta has an initial diameter of roughly 2.5–2.8 cm near its origin from the aortic arch, gradually tapering to approximately 2 cm at its termination.^[5]^[6] The term "descending aorta" historically differentiates it from the ascending aorta—which rises superiorly from the heart—and the intervening aortic arch, emphasizing its caudally directed course after the arch.^[7]

Embryological origin

The descending aorta originates from the paired dorsal aortae and the fourth pair of aortic arches during early embryonic development. In the third week of gestation, the ventral aortae fuse to form the aortic sac, from which six pairs of pharyngeal arch arteries (aortic arches) develop, connecting to the bilateral dorsal aortae. The dorsal aortae, initially paired, give rise to the descending aorta through a process of fusion, elongation, and selective regression of embryonic structures, while the fourth arches contribute to the proximal portions: the right fourth arch forms the proximal right subclavian artery, and the left fourth arch integrates into the medial aspect of the aortic arch leading to the descending aorta.^[8]^[9] Key developmental stages occur between weeks 4 and 5 of gestation. During this period, the right and left dorsal aortae fuse caudally to form a single midline descending aorta, extending from approximately vertebral levels T4 to L4, while the right dorsal aorta regresses proximal to the seventh intersegmental artery. This fusion is accompanied by elongation of the aorta and its caudal descent, coinciding with diaphragm formation in weeks 4 to 6, as the heart migrates inferiorly and the diaphragm partitions from surrounding mesenchyme, positioning the descending aorta posterior to the developing diaphragm. The fifth and portions of the sixth aortic arches regress, further remodeling the system to establish the mature configuration.^[9]^[10]^[8] Congenital anomalies of the descending aorta often arise from incomplete regression or persistence of embryonic structures. A double aortic arch results from the persistence of both right and left fourth arches, forming a vascular ring that encircles the trachea and esophagus, with about 70% of cases featuring a dominant right arch; this occurs in approximately 1 in 10,000 births and can lead to compressive symptoms. Situs abnormalities, such as a right-sided aortic arch (prevalence <0.1%), stem from failure of the right dorsal aorta to regress, often associated with congenital heart defects or heterotaxy syndromes. Vascular rings, including those from double aortic arches or aberrant subclavian arteries, represent persistent embryonic arch remnants that may compress adjacent structures, highlighting the critical role of precise regression during weeks 4 to 5.^[9]^[8]

Anatomy

Thoracic portion

The thoracic portion of the descending aorta begins at the lower border of the fourth thoracic vertebra (T4), immediately distal to the attachment of the ligamentum arteriosum, which connects the aortic arch to the pulmonary trunk as a remnant of the fetal ductus arteriosus.^[11] From this point, it descends through the posterior mediastinum, initially positioned slightly to the left of the midline and the vertebral column, before gradually inclining toward the midline as it continues inferiorly. This segment terminates at the aortic hiatus of the diaphragm, at the level of the twelfth thoracic vertebra (T12), where it passes through the diaphragm to become the abdominal aorta.^[12]^[13] The thoracic descending aorta exhibits a gentle curvature, with a subtle leftward deviation in its upper portion that shifts more centrally lower down, maintaining a relatively straight vertical path overall. Its initial diameter measures approximately 2.5 cm, tapering slightly as it descends, while the aortic wall thickness averages around 2 mm in adults.^[11]^[14] In terms of relations, the thoracic descending aorta lies anterior to the vertebral column and the hemiazygos and accessory hemiazygos veins, which course along its posterior aspect. Anteriorly, it is related to the esophagus and the pericardium, with the esophagus lying anterior to it in the lower thorax. To its right lies the azygos vein, which arches forward over the root of the right lung at about T4 before draining into the superior vena cava, while to the left are the left pleura, left lung, and portions of the esophagus.^[12]^[13]

Abdominal portion

The abdominal portion of the descending aorta, also known as the abdominal aorta, enters the abdomen through the aortic hiatus of the diaphragm at the level of the T12 vertebra.^[2] It then descends retroperitoneally along the posterior abdominal wall, running anterior to the lumbar vertebrae, and continues in a slightly tapered fashion until it bifurcates into the left and right common iliac arteries at the level of the L4 vertebra.^[2] This course positions the vessel as the primary conduit for oxygenated blood to the lower body and pelvic organs.^[15] The abdominal aorta maintains a midline position for most of its length, though it lies slightly to the left of the midline and is enveloped by the preaortic fascia, which provides structural support within the retroperitoneum.^[2] Its diameter typically measures approximately 2 cm, tapering gradually from its suprarenal segment toward the infrarenal portion and bifurcation, where it shifts slightly rightward to accommodate the adjacent inferior vena cava.^[16] This configuration ensures efficient blood distribution while minimizing compression from surrounding structures.^[15] In terms of specific relations, the abdominal aorta lies anterior to the lumbar vertebrae and the anterior aspects of the lumbar sympathetic trunks, which run parallel along the vertebral column.^[2] Anteriorly, in its upper segment, it is related to the body of the pancreas, while posteriorly to the left crus of the diaphragm at the aortic hiatus, while laterally it borders the medial aspects of the kidneys, with the right kidney positioned adjacent to the inferior vena cava on the aorta's right side.^[15] These relations highlight the aorta's protected yet accessible position in the retroperitoneal space, facilitating its interactions with nearby viscera.^[2]

Histology

The wall of the descending aorta, like other elastic arteries, consists of three distinct concentric layers: the tunica intima, tunica media, and tunica adventitia, which collectively provide structural integrity and elasticity to withstand pulsatile blood flow from the heart.^[17] The tunica intima forms the innermost layer and is composed of a simple squamous endothelium overlying a subendothelial layer of loose connective tissue, followed by an external elastic lamina that anchors it to the underlying media; this layer minimizes friction with blood and serves as a selective barrier.^[18] The tunica media, the thickest layer in the descending aorta, comprises alternating sheets of smooth muscle cells and elastic fibers organized into 50-70 fenestrated elastic lamellae, particularly numerous in the thoracic portion (approximately 53-78 lamellae) compared to the abdominal portion (around 28 lamellae), enabling the vessel to expand and recoil with each heartbeat.^[19] These elastic elements, interspersed with collagen fibers and proteoglycans, allow for pulse propagation and damping of pressure waves.^[20] The outermost tunica adventitia is a layer of loose connective tissue rich in collagen fibers, fibroblasts, and the vasa vasorum—small nutrient vessels that supply the outer two-thirds of the aortic wall—along with lymphatic vessels and nerves for structural support and nourishment. Compared to muscular arteries, the descending aorta exhibits a higher elastin content in its tunica media, with prominent elastic lamellae rather than a predominance of circumferentially arranged smooth muscle cells, which facilitates greater distensibility and the transmission of systolic pressure distally.^[21] This structural adaptation is essential for the aorta's role in buffering cardiac output fluctuations, distinguishing it from smaller distributing arteries that prioritize vasoconstriction over elasticity.^[22] With advancing age, the histology of the descending aorta undergoes progressive changes, including thickening of the tunica intima due to accumulation of extracellular matrix and smooth muscle-like cells, which increases susceptibility to atherosclerosis by promoting lipid deposition and plaque formation.^[23] Concurrently, degradation and fragmentation of elastin fibers in the tunica media occur through enzymatic proteolysis and oxidative stress, leading to reduced elasticity, increased stiffness, and a predisposition to aneurysmal dilation, particularly in the abdominal segment.^[24] These alterations reflect cumulative mechanical fatigue from repeated pulsations, with elastin content declining notably after the third decade of life.^[25]

Relations and branches

Adjacent structures

The descending aorta is closely related to several key structures along its thoracic and abdominal courses, influencing surgical approaches and imaging interpretations. In its thoracic portion, the esophagus lies anteriorly, initially positioned to the right before crossing to the left as the aorta descends through the posterior mediastinum. The thoracic duct ascends to the right of the descending thoracic aorta, between it and the azygos vein, posterior to the esophagus. The vagus nerves course laterally, contributing to the esophageal plexus anterior to the aorta and descending alongside the mediastinal structures. In the abdominal portion, the inferior vena cava is positioned immediately to the right of the aorta throughout its descent anterior to the lumbar vertebrae. The renal veins cross anteriorly, with the left renal vein passing between the aorta and the superior mesenteric artery to join the inferior vena cava. The psoas major muscles lie posterolaterally to the aorta, with the vessel positioned medial to them anterior to the vertebral column.^[26] The descending aorta bifurcates into the common iliac arteries at the level of the fourth lumbar vertebra, near the sacral promontory. This site is just superior to the confluence of the common iliac veins, which form the inferior vena cava at the fifth lumbar vertebra, with the left common iliac vein crossing posterior to the right common iliac artery.^[27]

Major branches

The descending aorta gives rise to several major branches that supply various thoracic and abdominal structures, categorized by its thoracic and abdominal portions.^[28]

Thoracic Portion Branches

The thoracic descending aorta, extending from the level of the fourth thoracic vertebra (T4) to the aortic hiatus at T12, originates nine pairs of posterior intercostal arteries, typically from the third to eleventh intercostal spaces (T3-T11), which arise posteriorly and course laterally to supply the intercostal spaces, thoracic wall, and pleura; these arteries often emerge at an acute angle relative to the aortic wall in their cranial origins.^[11]^[12]^[28] Additionally, it gives off the superior phrenic arteries, a pair of small vessels arising near the termination of the thoracic aorta to supply the superior surface of the diaphragm.^[11]^[12] It also gives rise to a pair of subcostal arteries near the aortic hiatus, which supply the 12th intercostal space and the anterolateral abdominal wall.^[11] Smaller visceral branches include the pericardial arteries (anterior, unpaired, supplying the posterior pericardium), esophageal branches (typically four to five, anterior, supplying the esophagus), and mediastinal branches (small, supplying mediastinal lymph nodes and tissues).^[12]^[28] The bronchial arteries, numbering two to three in total (usually one on the right and two on the left), arise directly from the anterior or anterolateral aspect of the thoracic aorta between T5 and T6 levels to supply the bronchi, lung roots, and associated structures; variations are common, with ectopic origins (e.g., from the aortic arch or subclavian artery) occurring in approximately 12.5% of cases.^[12]^[29]^[30]

Abdominal Portion Branches

The abdominal descending aorta, beginning at T12 and terminating at L4 by bifurcating into the common iliac arteries, issues its major branches in a predictable sequence along the vertebral levels. The celiac trunk arises anteriorly at T12 as the first major unpaired branch, giving rise to the left gastric, common hepatic, and splenic arteries.^[15]^[11] At L1, the superior mesenteric artery emerges anteriorly to supply midgut derivatives, while the paired renal arteries originate laterally at the L1-L2 interspace to perfuse the kidneys; accessory renal arteries, arising from the aorta or nearby vessels, occur in approximately 30% of individuals and may supply the upper or lower poles of the kidney.^[15]^[31] The gonadal arteries (testicular in males, ovarian in females) branch laterally at L2.^[15] The inferior mesenteric artery arises anteriorly at L3 to supply the hindgut, and the median sacral artery emerges posteriorly near the L4 bifurcation to descend along the sacrum.^[15]^[11] Four pairs of lumbar arteries arise posterolaterally from L1 to L4, continuing the series of the posterior intercostal arteries to supply the posterior abdominal wall and spinal structures.^[12]^[11]

Function and physiology

Blood flow dynamics

The blood flow through the descending aorta exhibits pulsatile characteristics driven by the cardiac cycle, featuring a systolic peak pressure of approximately 120 mmHg and a mean arterial pressure of 90-100 mmHg in healthy adults.^[32] Flow velocities typically range from 50 to 100 cm/s, with mean values around 50-75 cm/s in the thoracic portion decreasing slightly distally due to branching.^[33] These dynamics are governed by pressure gradients that propel blood forward, while pulse waves propagate along the vessel at speeds of 4-7 m/s in younger adults, increasing with age and reflecting arterial stiffness.^[34] A key hemodynamic principle in the descending aorta is the Windkessel effect, where the elastic walls expand during systole to accommodate the surge of blood (up to 70 mL per beat), storing energy and then recoiling in diastole to sustain forward flow and prevent abrupt drops in pressure.^[35] This compliance buffers the pulsatile input from the heart, maintaining diastolic perfusion to distal tissues, though it diminishes progressively with age due to elastin degradation and fibrosis, leading to higher systolic pressures and reduced overall arterial buffering capacity.^[36] Although aortic flow is unsteady and pulsatile, Poiseuille's law provides a conceptual framework for understanding viscous resistance, where flow resistance is inversely proportional to the fourth power of the vessel radius, highlighting the functional significance of the descending aorta's gradual tapering (from ~2.5 cm proximally to ~2 cm distally).^[37] This tapering increases peripheral resistance incrementally, helping to regulate pressure gradients and mitigate excessive pressure drops as blood is distributed to major branches, thereby optimizing systemic perfusion without requiring extreme proximal pressures.^[38]

Role in circulation

The descending aorta serves as a critical conduit in the systemic circulation, delivering oxygenated blood from the left ventricle to the lower portions of the body after it has been oxygenated in the pulmonary circulation. This segment begins at the aortic arch and extends through the thorax and abdomen, ensuring efficient distribution to vital structures below the diaphragm. By maintaining high-pressure flow, it integrates seamlessly with the overall cardiovascular system, supporting metabolic demands in the thorax, abdomen, pelvis, and lower extremities.^[2] Through its thoracic and abdominal branches, the descending aorta channels approximately 70% of the total cardiac output to these regions, accounting for the majority of systemic perfusion beyond the head, neck, and upper limbs. This substantial allocation underscores its primary role in sustaining lower body oxygenation and nutrient delivery, with the remaining output directed via the aortic arch branches to the upper body.^[39] Blood pressure within the descending aorta exhibits only a minimal longitudinal drop, with mean arterial pressure remaining relatively stable at around 90 mmHg from the arch to the bifurcation, preserving adequate driving force for downstream perfusion. This stability arises from the aorta's elastic properties, which buffer pulsatile flow into a steadier output. Additionally, autoregulatory mechanisms in the organs supplied by its branches—such as myogenic responses and metabolic feedback—help sustain consistent tissue blood flow despite minor fluctuations in aortic pressure.^[40]^[41]

Clinical significance

Common pathologies

The descending aorta is susceptible to several prevalent pathologies, primarily degenerative, inflammatory, and traumatic in nature, which can compromise its structural integrity and lead to life-threatening complications. These conditions often arise from a combination of hemodynamic stress, genetic predisposition, and environmental factors, with histological changes such as medial degeneration weakening the aortic wall and predisposing to disease progression.^[42] Inflammatory aortitis, such as giant cell arteritis and Takayasu arteritis, can affect the descending aorta, causing wall thickening, stenosis, or aneurysm formation, particularly in younger patients or those with autoimmune conditions. These may require immunosuppressive therapy alongside vascular management.^[43] Aortic aneurysm represents one of the most common degenerative pathologies, characterized by fusiform (spindle-shaped) or saccular (pouch-like) dilation exceeding 1.5 times the normal aortic diameter, typically greater than 3 cm in the thoracic portion and 4 cm in the abdominal portion. Etiologically, these aneurysms stem from progressive wall weakening due to atherosclerosis in the descending thoracic and abdominal segments, compounded by risk factors including hypertension, smoking, advanced age (most frequent after 65 years), male sex, and familial history. The thoracic descending subtype accounts for approximately 40% of all thoracic aortic aneurysms, with a prevalence of aortic dilations around 2-3% in elderly populations, while abdominal aortic aneurysms are more prevalent, affecting 5-10% of individuals over 65 years, particularly men. Symptoms are often absent until rupture or expansion occurs, manifesting as back or abdominal pain, pulsatile mass, or embolic events from mural thrombus.^[42]^[44]^[45] Aortic dissection is another critical pathology involving a tear in the intima layer, permitting blood to enter the media and create a false lumen that propagates along the aortic wall. In Stanford Type B dissections, which primarily affect the descending aorta distal to the left subclavian artery, the etiology is predominantly hypertension (present in up to 70% of cases), often exacerbated by atherosclerosis, connective tissue disorders like Marfan syndrome, or prior aneurysmal dilation. Symptoms typically include sudden, severe tearing pain in the back or chest radiating to the abdomen, potentially accompanied by hypotension, organ malperfusion (e.g., renal or mesenteric ischemia), or neurological deficits if branches are compromised. With medical management, uncomplicated Type B dissections have an in-hospital mortality rate of approximately 10-15%, while complicated cases (e.g., with rupture or malperfusion) exceed 30-40% without further intervention.^[46] Atherosclerosis frequently afflicts the descending aorta, manifesting as progressive plaque accumulation of lipids, cholesterol, calcium, and inflammatory cells within the intima, leading to luminal stenosis and reduced compliance. This condition is more pronounced in the abdominal portion due to turbulent blood flow at branch points (e.g., iliac bifurcation) and higher exposure to systemic risk factors like hyperlipidemia, diabetes, smoking, and hypertension, which damage the endothelium and promote plaque formation. Epidemiologically, atherosclerotic changes are nearly ubiquitous in the abdominal aorta by age 70, though significant stenosis causing ischemic symptoms such as claudication or visceral insufficiency is uncommon.^[47] Traumatic injuries to the descending aorta encompass penetrating, blunt, and iatrogenic mechanisms, often resulting in partial or complete wall disruption with high morbidity. Penetrating trauma, such as from gunshot or stab wounds, directly lacerates the vessel and predominates in abdominal aortic injuries, while blunt trauma—typically from high-speed deceleration in motor vehicle accidents—affects the thoracic descending aorta at the isthmus in 80-90% of cases, accounting for less than 1% of all blunt trauma but up to 15% of fatal crashes. Iatrogenic injuries occur during invasive procedures like spinal surgery, endovascular interventions, or esophagectomy, with an incidence of 0.02-0.2% in cardiac catheterizations leading to dissection or perforation. Symptoms vary by mechanism but commonly include acute chest or abdominal pain, hemodynamic instability, or pseudoaneurysm formation; overall mortality exceeds 50% without prompt intervention, driven by hemorrhage or delayed rupture.^[48]^[49]

Diagnostic and therapeutic approaches

Computed tomography (CT) angiography serves as the gold standard for imaging the descending aorta due to its high spatial resolution (sub-millimeter voxels), rapid acquisition, and widespread availability, enabling detailed evaluation of the lumen, wall, and periaortic structures with nearly 100% sensitivity and 98-99% specificity.^[50] It is particularly effective for the thoracic descending portion in acute settings, where speed minimizes motion artifacts. Magnetic resonance imaging (MRI) complements CT by providing superior soft tissue contrast without ionizing radiation, making it ideal for follow-up assessments of the descending aorta, though it is limited by longer scan times and susceptibility to artifacts from stents or motion.^[50] Transthoracic or transesophageal echocardiography is valuable for real-time evaluation of the thoracic descending aorta, especially in hemodynamically unstable patients, while duplex ultrasound enables noninvasive screening of the abdominal portion, detecting aneurysms with diameters as small as 3.0 cm.^[51] Diagnosis of descending aorta disorders relies on established criteria, such as an aneurysm diameter exceeding 5.5 cm in the descending thoracic or abdominal segments prompting consideration for intervention in low-risk patients, with lower thresholds (5.0 cm) for women or those with rapid growth (≥0.5 cm/year).^[52] For aortic dissection, elevated D-dimer levels (>500 ng/mL) exhibit high sensitivity (93-95%) as a rule-out biomarker in low-risk cases, helping avoid unnecessary advanced imaging.^[53] Therapeutic approaches prioritize endovascular techniques for descending aorta pathologies. Thoracic endovascular aortic repair (TEVAR) using stent-grafts achieves technical success rates over 99% for descending thoracic aneurysms ≥5.5 cm, reducing mortality odds by 40% compared to open repair (OR 0.6 for intact cases), with paraplegia rates below 5%.^[54] Endovascular aneurysm repair (EVAR) similarly yields success rates exceeding 90% for abdominal aortic aneurysms, with 30-day mortality under 1% and freedom from rupture approaching 95% at 5 years.^[55] Open surgical grafting remains indicated for rupture or complex anatomy unsuitable for endovascular access, though it carries higher perioperative risks (mortality 3-5%). Medical management, including beta-blockers to control hypertension and reduce aortic wall stress by lowering heart rate and dP/dt, is essential for all patients to slow aneurysm progression and prevent dissection extension.^[56] As of 2025, artificial intelligence (AI)-assisted imaging enhances early detection of descending aorta abnormalities, with machine learning models achieving AUROC scores of 0.94 for aortic stenosis screening via portable ultrasound, and new training tools facilitating point-of-care assessments for abdominal aortic aneurysms.^[57] Bioresorbable stents are in clinical trials for aortic endografts, promising reduced long-term inflammation and improved vascular healing through bioengineered materials that degrade over time.^[58]

References

[1]
What Is the Descending Aorta? - Cleveland Clinic
Your descending aorta is the longest part of your aorta, which is the largest artery in your body. It carries oxygen-rich blood from your heart through your ...
[2]
Anatomy, Abdomen and Pelvis: Aorta - StatPearls - NCBI Bookshelf
Jul 25, 2023 · The aorta is the first and largest artery in the body. It is responsible for transporting nutrient-rich blood to the systemic circulation following ejection.
[3]
Descending aorta | Radiology Reference Article - Radiopaedia.org
Aug 13, 2025 · The descending aorta is the continuation of the aortic arch in the posterior mediastinum. Gross anatomy. The descending aorta commences at ...Missing: divisions | Show results with:divisions
[4]
Reference for Normal Diameters of the Abdominal Aorta and ... - NIH
Oct 26, 2022 · The abdominal aorta length is approximately 13 cm [1]. Knowing the normal abdominal aorta diameter is a basis for diagnosing AAAs and ...
[5]
How to Measure an Abdominal Aorta Diameter ... - POCUS.org
Apr 17, 2024 · The normal abdominal aorta diameter in an average healthy adult is approximately 2.0 cm. When AAA diameter is 5.5 cm or more, it is ...
[6]
Aorta Anatomy - UF Health
May 19, 2025 · The aorta is the largest blood vessel in the body. This artery is responsible for transporting oxygen rich blood from your heart to the rest of your body.
[7]
Aortic Development and Anomalies - PMC - NIH
The ascending aorta divides into two arches that pass to either side of the esophagus and trachea and reunite to form the descending aorta (Fig. 15). Therefore, ...
[8]
Embryology, Aortic Arch - StatPearls - NCBI Bookshelf
Mar 6, 2023 · The descending aorta arises from the dorsal aortae. Early in development, paired right and left dorsal aortae are confluent with the aortic sac.Introduction · Development · Molecular Level · Function
[9]
Cardiac Neural Crest - PMC - PubMed Central - NIH
During 4–5 weeks of gestation, the bilaterally symmetric pharyngeal arch arteries and the right and left dorsal aortae undergo remodeling that is a sequence of ...
[10]
The Aorta - Branches - Aortic Arch - TeachMeAnatomy
### Summary of Thoracic Aorta Details
[11]
Aorta: Anatomy, branches, supply | Kenhub
It is the largest artery in the body, with its largest diameter being approximately 4 cm at the aortic root decreasing with distance; being about 3.5 cm in the ...
[12]
Descending aorta | Radiology Reference Article - Radiopaedia.org
Aug 13, 2025 · The descending aorta commences at the level of the fourth thoracic vertebra body, on its left, in the plane of Ludwig as the continuation of the aortic arch.
[13]
Evolution of Aortic Wall Thickness and Stiffness With Atherosclerosis
Mar 16, 2015 · Men had thicker aortic walls than women (for men the baseline measure was 2.40±0.44 mm, and during the MESA5 examination it was 2.75±0.26 mm for ...
[14]
Anatomy, Abdomen and Pelvis: Abdominal Aorta - StatPearls - NCBI
Aortic aneurysm (AA) describes an increased diameter in the ascending aorta to greater than 5.0 cm or descending aorta to greater than 4.0 cm (increase in ...Missing: course | Show results with:course
[15]
Aortic dimensions and the risk of dissection - PMC - NIH
The normal diameter of the ascending aorta has been defined as <2.1 cm/m2 and of the descending aorta as <1.6 cm/m2. The normal diameter of the abdominal aorta ...Aortic Dimensions And The... · Aneurysm Formation · Aortic Dimension And...
[16]
Histology, Blood Vascular System - StatPearls - NCBI Bookshelf
The tunica intima of the large arteries is quite thick with predominant smooth muscle in the subendothelial layer of the tunica intima.
[17]
Histology of blood vessels | Radiology Reference Article
Jul 26, 2024 · These are arranged into three concentric layers (or tunicae): intima, media and adventitia. the intima (or tunica intima). inner layer ...
[18]
Aortic Media - an overview | ScienceDirect Topics
The thoracic aortic media contains approximately 53–78 lamellar units [15,16], whereas the abdominal aortic media contains approximately 28 [15]. The numerous ...
[19]
Thoracic Aorta: Anatomy and Pathology - PMC - NIH
The descending aorta starts after the take-off of the left subclavian artery and has a thoracic and an abdominal segment. 3. Histology and Histogenesis of the ...
[20]
Anatomy, Blood Vessels - StatPearls - NCBI Bookshelf
Aug 8, 2023 · Muscular arteries contain more smooth muscle cells in the tunica media layer than the elastic arteries. Elastic arteries are those nearest the ...Introduction · Structure and Function · Embryology · Nerves
[21]
What Are Elastic Arteries? - Cleveland Clinic
Mar 1, 2023 · What is the difference between elastic arteries and muscular arteries? Elastic arteries have more elastic tissue in their middle layer ...
[22]
Morphology of the human aorta and age-related changes - NIH
They described histological features such as elastin fragmentation and fibrosis. It was found that these changes showed a correlation with age. Elastin ...
[23]
Quantitative Assessment of Aortic Elasticity With Aging Using ...
Apr 11, 2013 · The repeated cycles of distension and elastic recoil of the arterial wall accelerate the fragmentation and depletion of elastin, leading to a ...
[24]
Age-Related Changes in the Elastic Tissue of the Human Aorta
Nov 18, 2011 · The objective of this study is to gain further insights into the complex mechanism of elastic tissue ageing in human aortic blood vessels.Missing: descending | Show results with:descending
[25]
Anatomy, Thorax, Heart Aorta - StatPearls - NCBI Bookshelf
It originates from the left ventricle of the heart anterior to the pulmonary artery before arching posteriorly and descending along the posterior mediastinum.
[26]
Bronchial artery | Radiology Reference Article - Radiopaedia.org
Oct 14, 2025 · In addition, there are often additional smaller bronchial arteries arising from the descending thoracic aorta 7. They are small caliber arteries ...
[27]
Variations of bronchial artery origin in 600 patients - NIH
Jun 4, 2021 · Most BAs originated from the upper descending thoracic aorta, classified as orthotopic origin (n = 1464, 87.5%).2. Methods · 3. Results · 3.2. Ectopic Bas
[28]
The prevalence of accessory renal arteries in sudanese population ...
Apr 15, 2024 · In most individuals, a single renal artery arises from the abdominal aorta, but approximately 30% exhibit accessory renal arteries (aRA) [1].
[29]
Aortic Pressure - an overview | ScienceDirect Topics
The normal aortic systolic pressure is 90–140 mmHg, and the normal diastolic pressure is 60–90 mmHg. Central-aortic waveforms have a rapid upstroke, a systolic ...
[30]
Distribution of Blood Flow Velocity in the Normal Aorta - NIH
Peak systole was defined as the time frame in the cardiac cycle where the velocity magnitude average over the entire volume of the thoracic aorta was maximal.
[31]
Update on the Use of Pulse Wave Velocity to Measure Age-Related ...
Dec 30, 2023 · In contrast, PWV using aortic measurements in normal adults ranged from 4.5 ± 0.5 m/s in the 21–30-year-age group to 6.8 ± 1.0 m/s in the 61–70- ...
[32]
The arterial Windkessel | Medical & Biological Engineering ...
Jun 10, 2008 · Frank's Windkessel model described the hemodynamics of the arterial system in terms of resistance and compliance.Missing: descending | Show results with:descending
[33]
Windkessel effect – Knowledge and References - Taylor & Francis
One consequence of the loss of arterial elasticity with age is that this aortic hydraulic filter becomes less effective.
[34]
Determinants of Resistance to Flow (Poiseuille's Equation)
There are three primary factors that determine the resistance to blood flow within a single vessel: vessel diameter (or radius), vessel length, and viscosity ...
[35]
Role of tapering in aortic wave reflection: hydraulic and ... - PubMed
Abstract. Pressure and flow have been measured simultaneously at six locations along the aorta of an anatomically correct 1:1 scale hydraulic elastic tube model ...Missing: regulation poiseuille
[36]
Measurement of aortal blood flow in supranormal cardiac output - PMC
Blood flow in the descending aorta is assumed to represent approximately 70% of total cardiac output, accordingly 70% of the value measured with the invasive ...Missing: percentage | Show results with:percentage
[37]
Systemic Circulation - CV Physiology
Past the arch, the aorta descends downward (descending aorta) through the thorax (thoracic aorta) where it gives off several small arterial vessels to supply ...
[38]
Autoregulation of Organ Blood Flow - CV Physiology
Autoregulation is a manifestation of local blood flow regulation. It is defined as the intrinsic ability of an organ to maintain a constant blood flow ...
[39]
Thoracic and Abdominal Aortic Aneurysms | Circulation
Feb 15, 2005 · Thoracic aneurysms may involve one or more aortic segments (aortic root, ascending aorta, arch, or descending aorta) and are classified ...Thoracic Aortic Aneurysms · Ascending Thoracic Aortic... · Abdominal Aortic Aneurysms<|control11|><|separator|>
[40]
Population-Based Risk Factors for Ascending, Arch, Descending ...
Jul 12, 2021 · Well-recognized risk factors for abdominal dilations include male sex, smoking, hypertension, previous history of cardiovascular disease (CVD), familial ...
[41]
Thoracic aortic aneurysm | Radiology Reference Article
Jul 11, 2025 · Most commonly occur in the 50 to 60-year-old age group with an estimated incidence of ~7.5 per 100,000 patient-years 8. There is a male ...
[42]
Aortic Dissection - StatPearls - NCBI Bookshelf - NIH
Oct 6, 2024 · This process can lead to a sudden drop in systemic blood pressure and cause catastrophic complications such as hemopericardium and cardiac ...
[43]
What is Atherosclerosis of the Aorta? - Cleveland Clinic
Atherosclerosis of the aorta is a progressive buildup of plaque in the largest artery in your body, called your aorta.
[44]
Turbulent blood flow plays an essential localizing role in the ... - NIH
In other words, turbulent blood flow plays an essential localizing role in plaque formation in experimentally induced hypercholesterolaemic rats. Although ...
[45]
Traumatic Aortic Injuries - StatPearls - NCBI Bookshelf
Mar 19, 2024 · A traumatic aortic injury is characterized by damage to the vessel wall or rupture of the vessel secondary to penetrating or blunt force trauma.Missing: iatrogenic | Show results with:iatrogenic
[46]
Iatrogenic Delayed Aortic Injury Following a Surgical Stabilization of ...
Dec 31, 2018 · It usually occurs at the aortic isthmus just distal to the left subclavian artery by rapid deceleration [1,2], but other sites can be affected.
[47]
CT and MR imaging of the thoracic aorta - PMC - PubMed Central
Jun 23, 2016 · Both CT and MRI are considered the best imaging modalities for the study of the thoracic aorta. CT is faster, less sensitive to movement artifacts and provides ...
[48]
Cardiac Imaging & Cardiac Testing | University of Utah Health
We offer a full range of vascular studies and diagnostic testing. These include noninvasive procedures like a vascular ultrasound, cardiac CT scans, ...
[49]
2022 ACC/AHA Guideline for the Diagnosis and Management of ...
Nov 2, 2022 · Aortic dissection occurs when there is an intimal tear that allows the blood to pass through the tear and into the aortic media, splitting the ...
[50]
D-dimer as a Rule-Out for Aortic Dissection - PMC - NIH
Dec 8, 2023 · Type B aortic dissections had a D-dimer below 500 ng/mL at 1 hr post-admission [15]. It is possible that an overrepresentation of Type A or Type ...
[51]
https://healthcare.utah.edu/cardiovascular/imaging
[52]
Endovascular abdominal aortic aneurysm repair in the geriatric ...
A total of 15 studies were identified. EVAR in this population is efficient with a success rate exceeding 90% in all cases, and safe, with early mortality and ...
[53]
Medical Management of Aortic Disease: If They Don't Need Surgery ...
Mar 7, 2023 · Beta-blockers decrease stress on the aortic wall by reducing heart rate and blood pressure, hence slowing the progression of dissection and ...Abstract · Aortic Aneurysms · Aortic Dissection · Inflammatory Aortic Diseases
[54]
Butterfly Network Advances AI-Powered Aortic Valve and Aorta ...
Results highlight the role of artificial intelligence development in enabling earlier detection of aortic stenosis.
[55]
Aortic Endograft Market Size, Trends & Growth 2025 to 2035
Feb 22, 2025 · Trends include AI-driven imaging, bioresorbable stents, outpatient EVAR procedures, and expansion in emerging markets. Table of Content.