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References
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[1]
What is a Nuclear Microreactor? - Department of EnergyMicroreactors are compact reactors that will be small enough to transport by truck and could help solve energy challenges in a number of areas.Missing: engineering | Show results with:engineering
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[2]
Microreactors - Idaho National LaboratoryA microreactor is a small nuclear reactor that can operate as part of the electric grid, independently from the electric grid, or as part of a microgrid.
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[3]
[PDF] GAO-20-380SP, Science & Tech Spotlight: Nuclear MicroreactorsNuclear microreactors are very small reactors usually generating less than 50 megawatts electric (MWe). They are seen as an alternative to small modular (50-300 ...Missing: engineering | Show results with:engineering
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[5]
Microreactor - an overview | ScienceDirect TopicsIn general, microreactors are miniaturized chemical reaction systems that contain parallel reaction channels with typical diameters between 10 and 500 μm. These ...
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[6]
Microstructured Catalytic Reactors - ScienceDirect.comOne of the main characteristics of MSRs is the high surface-to-volume ratio, which is in the range of 10,000–50,000 m2 m− 3. For comparison, the surface-to- ...
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[8]
Scale-up of micro- and milli-reactors: An overview of strategies ...For the investigated conditions of low flow rate and low Reynolds numbers, the flow is considered as incompressible, laminar and steady state with constant ...
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[10]
A review on microreactors: Reactor fabrication, design, and cutting ...Nov 2, 2018 · Herein, we describe the fabrication, commercial aspects, design principles, and cutting-edge applications of microreactors.
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[12]
Micro-Channel Reactor - an overview | ScienceDirect TopicsA micro-channel reactor has channels with a hydraulic diameter of 10-200 μm, enhancing mixing and control over reaction time and temperature.
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[13]
A Review of Heating and Temperature Control in Microfluidic SystemsDepending on the heater power used, the local channel temperature was 10 to 19 °C above the room temperature, enabling control of flow rates from 0.33 to 4.7 µL ...
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[14]
Dynamics and control of integrated microchemical systems with ...Early efforts beginning in the mid-1970s led to the use of silicon ... Microfabricated differential reactor for heterogeneous gas phase catalyst testing ...
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[15]
Synergy of Microtechnology and Biotechnology: Microreactors ... - NIHThe mid-1990s are usually considered the beginning of the era of microreactor technology (2, 3), which has been growing almost exponentially ever since.
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[16]
The history of microfluidics - ElveflowIn 1990, he published a paper in which he introduced the concept of miniaturized “total chemical analysis system”, abbreviated to “ µ-TAS”, for chemical sensing ...
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[17]
[PDF] Silicon-technology based microreactors for high-temperature ...microreactor for high temperature catalytic gas phase reactions; Sens. Actuators A, 112 (2-3), (2004), pp. 267-277. [44] G. Veser, G. Friedrich, M. Freygang ...
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[18]
Microreactors could redefine chemistry, nanodrip by drop ...Wolfgang Ehrfeld, who helped pioneer microreaction technology in the early 1990s, started Ehrfeld Mikrotechnik AG in 2000 after leaving the IMM. Ehrfeld ...
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[19]
Chemical microreactors and method for producing sameAccording to this the chemical microreactors are suitable for manufacturing toxic, unstable or explosive chemical products, particularly of cyanogen chloride, ...Missing: early hazardous
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[20]
Microreaction engineering — is small better? - ScienceDirect.comMicrofabricated chemical systems are expected to have a number of advantages for chemical synthesis, chemical kinetics studies, and process development.
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[21]
30 Years of Thermal Cycler Innovations #1: The World's First ...Mar 9, 2017 · The invention of an all-in-one machine (thermal cycler) that would help automate the PCR process changed history for molecular biology researchers.Missing: late precursor
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[22]
International Conference on Microreaction Technology (IMRET17)The series of International Conferences on Microreaction Technology (IMRET) started in 1997 with IMRET 1 being held in Frankfurt, Germany.
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[23]
Realize the Potential of Process Intensification - AIChEWith a history that dates back to the 1970s, process intensification (PI) is not a new concept. Several developments have moved PI forward, but realizing ...
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[25]
Manufacturing in the 21st Century: Continuous Flow Chemistry has ...Nov 21, 2014 · The basis of the technology can be found in early patents dating back to the 1950's. ... Couple this with the ability to run many hazardous ...
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[26]
Machine learning-assisted discovery of flow reactor designs - NatureAug 5, 2024 · We have established a machine learning-assisted approach for the design of new chemical reactors, combining the application of high-dimensional ...
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Deep Reinforcement Learning-Based Self-Optimization of Flow ...May 13, 2025 · This paper demonstrates the capabilities of deep reinforcement learning (DRL) as an effective self-optimization strategy for imine synthesis in flow.Missing: post- | Show results with:post-<|control11|><|separator|>
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[28]
Recent advances in 3D printing for continuous flow chemistryLaboratories worldwide have rapidly realized the potential of 3D printing as an invaluable tool for rapid prototyping and creating complex laboratory apparatus ...
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[29]
Heterogeneous photoredox flow chemistry for the scalable ... - NatureMar 6, 2020 · We report the merging of flow chemistry with heterogeneous photoredox catalysis for the facile production of high value compounds in a continuous flow reactor.
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[30]
FDA Allows First Switch From Batch to Continuous Manufacturing for ...Apr 12, 2016 · The US Food and Drug Administration (FDA) for the first time in its history allowed a manufacturer to switch from the more antiquated batch manufacturing ...
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[31]
Process intensification of biodiesel production using pilot-scale ...This study aims to enhance biodiesel production through a pilot-scale continuous multiple baffle reactor. This reactor incorporates a baffle array with ...
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[32]
Evolution of the Synthesis of Remdesivir. Classical Approaches and ...Jul 23, 2021 · Development of a large-scale cyanation process using continuous flow chemistry en route to the synthesis of remdesivir. Org. Process Res ...
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[33]
Sustainable catalytic epoxidation of biorenewable terpene ...Solvent-free continuous flow epoxidation of the alkene bonds of a range of biorenewable terpene substrates have been carried out using a recyclable tungsten ...
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[34]
Recent Advances in Droplet Microfluidics | Analytical ChemistryDroplet-based microfluidic systems have become an indispensable and embedded tool within contemporary chemical and biological science.
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[35]
Autonomous continuous flow reactor synthesis for scalable atom ...Jeraal et al. described a machine learning-enabled autonomous flow chemistry platform for process optimization of multiple reaction metrics [41]. They ...Missing: post- | Show results with:post-
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[36]
Microreactor-Based Green Synthetic Platform for Flow Synthesis of ...This review focuses on the exciting progress in microreactor-based bio/organocatalytic ring-opening polymerizations to biodegradable polymers. The protocol of ...Introduction · Figure 3 · Author Information
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[37]
Flow Chemistry Europe: WelcomeFlow Chemistry Europe 2026 (FCE-26) marks the 14th edition of Europe's premier conference dedicated to the advancement of flow chemistry. Taking place over ...Missing: expansion growth
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[38]
Pd-loaded hypercrosslinked microreactors for the flow synthesis of ...Pd-loaded polyHIPE microreactors were coupled with polyHIPE micromixers for the continuous-flow synthesis of paracetamol, achieving a yield of 66%.
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[39]
Sustainability of flow chemistry and microreaction technologyJul 17, 2024 · This critical review provides an overview of the sustainability outcomes associated with flow chemistry, as a new concept in process chemistry.
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[40]
Sustainability and Techno-Economic Assessment of Batch and Flow ...Feb 14, 2025 · From circular synthesis to material manufacturing: advances, challenges, and future steps for using flow chemistry in novel application area.
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[41]
Batch Reactor Energy Consumption: A Comparison - AM TechnologySummary. Even without a heat integration network, the RTR requires 27 times less peak heating and 5.9 times less peak cooling than an equivalent batch reactor.
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[42]
[PDF] Microreactors and Microfluidic Cells in Organic SynthesisDec 12, 2007 · n Microreactors can lead to increased yields and selectivties through rapid mixing and better thermal management.
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[43]
[PDF] Exploration of the Application of Microreactor Technology in the ...The heat transfer efficiency of microreactors is 1-2 orders of magnitude higher than traditional reactors, and the mass transfer efficiency is increased by 3-5 ...Missing: conventional | Show results with:conventional
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[44]
A Review of Microreactors for Process Intensification - MDPIAug 28, 2024 · Microreactors are microfluidic devices with dimensions typically falling within the 10–1000 μm range. They are distinguishable from conventional ...
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[45]
Going Small, Thinking Big | Pharma ManufacturingThe following firms are some, certainly not all, of those pioneering microreactor technology and microfluidics: ... Wolfgang Ehrfeld, recently purchased by Bayer ...
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[46]
An Overview of Flow Features and Mixing in Micro T and Arrow MixersFor very low Reynolds numbers, the two inlet streams remain completely segregated in the mixing channel (stratified or segregated or laminar regime). In this ...
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[47]
Continuous flowing micro-reactor for aqueous reaction at ... - NIHWhen the reaction temperature is higher than 100 °C, an autoclave reactor is usually required to elevate the boiling point of the water by creating a ...
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[48]
Design and Scaling Up of Microchemical Systems: A ReviewJun 7, 2017 · This review defines the microchemical system and describes its components and applications as well as the basic structures of micromixers. We ...
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[49]
A Microreactor for Microwave-Assisted Capillary (Continuous Flow ...A capillary-based flow system has been developed for conducting microscale organic synthesis with the aid of microwave irradiation.
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[50]
Microfluidic Mixing: A Review - PMC - NIHActive microfluidic mixers enhance the mixing performance by stirring or agitating the fluid flow using some form of external energy supply. As shown in Figure ...
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[51]
Microfluidic Magnetic Mixing at Low Reynolds Numbers and ... - MDPIThis review article focuses on the advantages of magnetic bead mixing along with recommendations on improving mixing in low Reynolds number flows.
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[52]
Micromixers—a review on passive and active mixing principlesActive mixing can be accomplished by time-pulsing flow owing to a periodical change of pumping energy or electrical fields, acoustic fluid shaking, ultrasound, ...
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[53]
A Review on the Hydrodynamics of Taylor Flow in MicrochannelsThis review paper highlights the hydrodynamic aspects of gas–liquid and liquid–liquid two-phase flows in microchannels.
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[54]
Hydrodynamics of slug flow inside capillaries - ScienceDirect.comSlug flow is characterised by the pseudo-periodic occurrence of large capsule-shaped bubbles, frequently referred to as Taylor bubbles or gas slugs.
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[55]
Engineering Photocatalytic Membrane Reactors for Sustainable ...By integrating photocatalysis with membrane separation, PMRs provide an optimal pathway for efficient photocatalyst recovery and sustainable system operation.Missing: disc | Show results with:disc
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[56]
The spinning disc reactor for photocatalytic degradationA spinning disc reactor is a device in which mixing and mass transfer processes are intensified by creating a centrifugal field. Restriction of the ...
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[57]
Sustainable and Advanced LED-Implanted Microfluidic Photoreactor ...Oct 4, 2024 · This work describes the use of a novel optofluidic Lab-on-a-Chip technology for safer, energy-efficient, and expedited synthesis of benzimidazole derivatives ...Missing: integration | Show results with:integration
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[58]
Analysis and Application of UV-LED Photoreactors for Phenol ...Three UV-LED photoreactors were tested for phenol removal. The internal-radiation photoreactor achieved the highest degradation efficiency, reaching 97.79%.2. Results And Discussion · 2.1. Photoreactors · 2.2. Photocatalytic...<|separator|>
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[59]
Microfluidic High-Throughput Platforms for Discovery of Novel ...High-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and ...
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[60]
From Batch to Continuous Chemical Synthesis—A Toolbox ApproachA toolbox approach for the transfer of batch to continuous chemical synthesis is presented. The approach considers reaction kinetics (Type A, B, C), ...
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[61]
Continuous flow ZIF-8/NaA composite membrane microreactor for ...Nearly 100% product yield could be obtained using this MMR under mild conditions. •. The MMR exhibited excellent long-time stability for the Knoevenagel ...
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[62]
Greener Approaches to Organic Synthesis Using Microreactor ...Unlike typical benchtop chemistry, microreactors have a modular design that enables mass production, as well as a small size that allows for multiple units to ...
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[63]
Heterogeneous nitration of nitrobenzene in microreactors: Process ...Nov 5, 2023 · In this work, a continuous flow microreactor system was developed for the nitration of nitrobenzene. Under the premise of high conversion and ...
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[64]
Direct fluorination of carbon monoxide in microreactors - ScienceDirectThe direct fluorination of carbon monoxide with pure fluorine is highly exothermic, thus difficult to control. It can easily develop into a thermal runaway ...Missing: hazardous | Show results with:hazardous
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A continuous flow microreactor as a practical tool for the synthesis of ...Small surface to volume ratios of microreactors allow more efficient absorption of heat generated from a reaction than do conventional batch reactors. In an ...
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[66]
Flow photochemistry — from microreactors to large-scale processingThe upscaling of flow photoreactors without compromising the reactor performances, however, remains a major challenge for large-scale processes. This review ...
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[67]
Technological Innovations in Photochemistry for Organic SynthesisAug 10, 2021 · We provide a comprehensive overview of these exciting technological advances, including flow chemistry, high-throughput experimentation, reactor design and ...<|control11|><|separator|>
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[68]
Flow Chemistry: Recent Developments in the Synthesis of ...Nov 26, 2015 · In this review we focused our attention only on very recent advances in the continuous flow multistep synthesis of organic molecules which found application as ...
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[69]
Modular microfluidic reactor and inline filtration system for the ...Many advantages have been reported with the use of microfluidic reactors, including more precise control over reaction conditions, real time monitoring of ...Missing: optimization | Show results with:optimization
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[70]
Modeling of Lipase Catalyzed Ring-Opening Polymerization of ε ...As lipases can degrade polyesters, a maximum in the molecular weight with time was obtained due to the competition of ring opening polymerization and ...
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[71]
Microfluidic immobilized enzyme reactors for continuous biocatalysisMicrofluidic immobilized enzyme reactors (μ-IMERs) offer fast reaction rates, high storage stability, low energy consumption, and rapid heat exchange.Missing: microchannels | Show results with:microchannels
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Enzyme Immobilization in Wall-Coated Flow Microreactors - PubMedFlow microreactors are emergent engineering tools for the development of continuous biocatalytic transformations. Exploiting enzymes in continuous mode ...
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Microfluidic Immobilized Enzymatic Reactors for Proteomic Analyses ...A common feature of microreactors is their high specific surface area, which can enable a fast reaction rate. The utilization of enzymes in reactors has been ...Microfluidic Immobilized... · 3. Immobilization Of Enzymes · 4. Proteomic Applications
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[74]
Cell Culture in Microfluidic Droplets | Chemical ReviewsFeb 18, 2022 · Here we review the emergence of droplet microfluidic methods for culturing cells and studying their interactions.
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[75]
Droplet-based cell-laden microgels for high-throughput analysisCell-laden droplet microfluidics has revolutionized bulk biochemical analysis by offering compartmentalized microreactors for individual cells, ...
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[76]
A review on continuous-flow microfluidic PCR in dropletsMar 31, 2016 · Discrete droplets have been exploited in the conventional PCR devices to provide a high throughput method for DNA sequencing [14], [15]. Droplet ...Review · 2. Microfluidic Pcr In... · 3.2. 2. On-Chip Integration
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[77]
Rapid PCR powered by microfluidics: A quick review under the ...Jun 24, 2021 · In principle, sensitivity is directly affected by the size of a PCR reactor, or the available nucleic acid templates. Normally, to achieve high ...
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[78]
NMR reaction monitoring in flow synthesis - BJOCIn this paper we focus on the coupling of nuclear magnetic resonance spectroscopy with flow and microreactor systems for the rapid analysis and optimization of ...
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[79]
mixing microfluidic chip for real-time NMR monitoring of ...The microfluidic chip uses a split-and-recombination mixer to rapidly mix solutions for real-time NMR monitoring of macromolecular reactions, like protein ...Missing: elucidation | Show results with:elucidation
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A mid-infrared lab-on-a-chip for dynamic reaction monitoring - NatureAug 13, 2022 · One common way to measure the absorbance of liquids in the mid-IR spectral range is based on attenuated total reflection (ATR) spectroscopy. In ...
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[81]
Modular microreactor with integrated reflection element for online ...Oct 3, 2020 · We report on the fabrication of an internal reflection element (IRE) combined with a modular polymer microfluidic chip that can be used for attenuated total ...Missing: reflectance | Show results with:reflectance
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[82]
Improved Method for Kinetic Studies in Microreactors Using Flow ...A novel method has been devised to derive kinetic information about reactions in microfluidic systems. Advantages have been demonstrated over conventional ...
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[83]
Droplet microreactor for high-throughput fluorescence-based ...Mar 30, 2023 · We report the development of a droplet microreactor for high-throughput fluorescence-based measurements of the acidities of individual particles.
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[84]
Boosted activity by engineering the enzyme microenvironment in ...Engineering of enzyme microenvironment can surprisingly boost the apparent activity. However, the underlying regulation mechanism is not well-studied at a ...Missing: 10x | Show results with:10x
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[85]
Review Microscale immobilized enzyme reactors in proteomicsThis review focuses on the latest developments associated with the preparation and application of microscale enzyme reactors for proteomics applications since ...Missing: post- | Show results with:post-
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[86]
Sustainable REACTOR and microreactor designS for boosting ...The EU-funded REACTORS 5.0 project aims to develop new sustainable reactor and micro-reactor concepts using cutting-edge technology.
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[87]
Electro- and photochemical microreactors intensified by acousticsMar 17, 2025 · The EU-funded MicroDisco project will exploit the synergistic effect of ultrasound on intensified electro- and photochemical reactors. The ...
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[88]
Artificial intelligence-driven platform for catalytic reactor discovery ...Feb 20, 2025 · This study introduces Reac-Discovery, a digital platform that integrates the generation, fabrication, and optimization of catalytic reactors ...
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[89]
Packed Bed Microreactors for Sustainable ChemistryIn this review, the recent development in the use of packed bed microreactors as a versatile research tool and intensified production unit will be highlighted.
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[90]
Microchemical systems for the synthesis of nanostructures : quantum ...We have developed a continuous multi-stage high-temperature and high-pressure microfluidic system. High-pressure conditions enabled the use low molecular ...Missing: papers | Show results with:papers
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[91]
(PDF) Democratizing Microreactor Technology for Accelerated ...Oct 12, 2025 · This survey paper provides an in-depth review of recent advancements in microreactor technologies, focusing on their role in facilitating ...
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[92]
Microreactor platform for continuous synthesis of electronic doped ...Jun 10, 2022 · A microreactor platform is used for continuous synthesis of electronic doped quantum dots (Ed-QDs) using a reverse cation exchange reaction at ...Missing: papers | Show results with:papers
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[93]
reaCtor | Fibre based plasmonic microreactor | HannoverIn project reaCtor we are laying the foundation for sustainable and eco-friendly flow photochemistry using functionalized fibers as microreactors, ...Missing: collaborations | Show results with:collaborations
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[94]
IMRET17 – OCTOBER 27-30 2024The series of International Conferences on Microreaction Technology (IMRET) started in 1997 with IMRET 1 being held in Frankfurt, Germany.Missing: 1995 | Show results with:1995
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[95]
(PDF) Open-Source Microreactor Design Models for ... - ResearchGateJul 28, 2025 · PDF | On Jan 1, 2025, Khaldoon Al-Dawood and others published Open-Source Microreactor Design Models for Technoeconomic Assessment | Find, ...
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[96]
Microreactor Technology Market Size | Industry Report, 2033The global microreactor technology market size was estimated at USD 597.9 million in 2024 and is projected to reach USD 1408.4 million by 2033, ...Missing: publications 2020-2025
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[97]
Global Microreactor Technology Market Size To Worth USD 759.94 ...Sep 10, 2024 · Companies covered: Corning, Chemtrix, Little Things Factory, AM Technology, Soken Chemical and Engineering, Ehrfeld Mikrotechnik BTS, ...
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[98]
Microreactor Technology Market Size, Share and Forecast 2032The Microreactor Technology Market is expected to grow significantly, increasing from USD 156697.86 million in 2024 to USD 646421.31 million by 2032, ...Missing: publications papers
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[99]
Microreactor Technology Market Size & Forecast 2026-2035The specialty chemicals segment is likely to hold microreactor technology market share of more than 38.7% by 2035. Micro reactor-based chemical synthesis has ...
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[100]
Advancements in microreactor technology for hydrogen production ...Nov 30, 2023 · The microreactor combined with a fuel cell can provide uninterrupted electricity as long as fuel and water are supplied, unlike lithium-ion ...
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[102]
ICH guideline Q13 on continuous manufacturing of drug substances ...This guideline describes scientific and regulatory considerations for the development, implementation, operation, and lifecycle management of continuous ...Missing: microreactors | Show results with:microreactors
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[104]
Mini-Monoplant Technology for Pharmaceutical ManufacturingAug 26, 2020 · This article describes a method for developing intensified and dedicated pharmaceutical processes, known as mini-monoplants.Introduction · Process Intensification · Mini-Monoplant Concept · Conclusions
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