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Trimeresurus

Trimeresurus is a genus of venomous pit vipers commonly known as Asian palm pit vipers or green pit vipers, belonging to the subfamily Crotalinae within the family Viperidae, characterized by their heat-sensing loreal pits and primarily arboreal lifestyle.^[1] Comprising 57 species as of November 2025, these snakes are predominantly green or brownish in coloration, aiding camouflage in forested environments, and are equipped with hemotoxic venom that can cause significant medical issues in human populations.^[2] The genus was established by Lacépède in 1804, with its type species being Trimeresurus gramineus.^[3] These pit vipers are distributed across eastern and southeastern Asia, ranging from the Indian subcontinent (including the Western Ghats and northeastern regions) through southern China, Myanmar, Thailand, Laos, Vietnam, Cambodia, Malaysia, Indonesia, and extending to some Pacific islands.^[4] Habitats typically include tropical rainforests, subtropical forests, karst landscapes, and mountainous areas up to elevations of 2,000 meters, where they often perch on vegetation or low branches during the day and become active at night.^[5] Many species exhibit sexual dimorphism, with males possessing longer tails and brighter coloration, and their diet consists mainly of small mammals, birds, frogs, and lizards.^[1] Trimeresurus species are medically significant, accounting for a substantial proportion of snakebites in Southeast Asia due to their proximity to human settlements and nocturnal habits.^[6] Ongoing taxonomic research, driven by molecular phylogenetics, continues to reveal cryptic diversity and refine species boundaries, with several new species described in recent years from biodiversity hotspots like the Indo-Burma region.^[7] Conservation concerns vary by species, with some facing threats from habitat loss and collection for the pet trade or traditional medicine.^[4]

Classification

Taxonomy

The genus Trimeresurus was established by Bernard-Germain-Étienne de La Ville-sur-Îllon, comte de Lacépède, in 1804, with the name derived from the Greek words trimerēs (meaning "three parts," referring to the three enlarged scales on the snout) and ourá (meaning "tail").^[8] The type species is Trimeresurus gramineus (formerly placed in Crotalus), reflecting early classifications where Asian pit vipers were initially grouped under the New World genus Crotalus by earlier authors like Wagler in 1830.^[9] Historically, the genus underwent significant revisions in the late 19th and 20th centuries. Species were separated from Crotalus due to distinct morphological features, such as the presence of heat-sensing pit organs and arboreal adaptations, with key contributions from Albert Günther's 1889 catalogue of snakes in the British Museum, which described several Trimeresurus taxa and clarified diagnostic traits like scale patterns and hemipenial morphology.^[10] Further refinements occurred through works like Maslin's 1942 key to the genus, emphasizing separation from Bothrops and establishing Trimeresurus as a distinct Asian lineage within Viperidae.^[11] Currently, Trimeresurus is recognized as a genus in the subfamily Crotalinae of the family Viperidae, encompassing 57 valid species as of November 2025, primarily arboreal green pit vipers distributed across Asia.^[12] Taxonomic debates persist regarding its monophyly, with molecular phylogenetics from 2016–2023 proposing splits into up to seven genera based on clades defined by mitochondrial and nuclear DNA; for instance, larger terrestrial forms are often placed in Protobothrops (e.g., P. jerdonii), while some arboreal species align with Cryptelytrops (e.g., C. albolabris complex), and the T. albolabris group forms a distinct subclade supported by cytochrome b and 16S rRNA analyses.^[13]^[14] These revisions highlight the genus's morphological heterogeneity, including variations in supralabial counts and dorsal scale rows.^[15] Phylogenetically, Trimeresurus occupies a basal position among Asian pit vipers, forming a sister clade to New World crotalines alongside genera like Gloydius, Ovophis, and Protobothrops, as evidenced by multilocus analyses of mtDNA (e.g., ND4, cyt b) and nuclear genes (e.g., CMOS, PRLR).^[13] Molecular dating indicates diversification began in the Miocene (approximately 23–5 million years ago), driven by tectonic uplift in Southeast Asia and habitat fragmentation, with Trimeresurus radiating into humid forest niches. Recent updates include 2023 revisions to the T. popeiorum complex, where integrative taxonomy using morphology, hemipenial structure, and mtDNA split it into multiple species, such as restricting T. popeiorum to central Vietnam and elevating T. caudornatus (originally described in 2020) as valid based on genetic divergence exceeding 5% in COI barcodes.^[16] Additionally, 2024 studies proposed two new cryptic species from the Indo-Burma hotspot within this group, using ecological niche modeling and phylogenomics to resolve boundaries, while T. uetzi was described in 2023 from Nepal, emphasizing ongoing refinements via total-evidence approaches.^[1]^[17]

Species

The genus Trimeresurus currently comprises 57 recognized species, reflecting ongoing taxonomic revisions based on morphological, molecular, and phylogenetic analyses.^[18] This number has increased significantly in recent years due to discoveries in biodiversity hotspots like the Himalayas, Western Ghats, and Southeast Asian islands, with at least 13 new species described since 2010. The type species is Trimeresurus gramineus Wagler, 1827, originally described from India.^[15] Many species exhibit cryptic diversity, leading to splits from complexes like the T. albolabris and T. popeiorum groups. Note that some species listed in older classifications have been transferred to other genera such as Protobothrops based on recent phylogenetic studies. Below is a complete list of recognized species, including authors, years of description, type localities, and brief notes on synonyms or conservation status where applicable (IUCN statuses are noted for select species; many remain unassessed). This compilation draws from recent taxonomic syntheses and primary descriptions, emphasizing post-2010 additions to highlight dynamism. Species confirmed to be in other genera (e.g., Protobothrops) have been excluded.

Species	Author(s) and Year	Type Locality	Notes
T. albolabris	Gray, 1842	Java, Indonesia	White-lipped pit viper; formerly included L. monticola as synonym; Least Concern (IUCN).^[15]
T. andersonii	Boulenger, 1892	Andaman Islands, India	Synonym: T. andamanensis; Vulnerable (IUCN).
T. arunachalensis	Captain et al., 2019	Arunachal Pradesh, India	Recently described from eastern Himalayas; molecularly distinct from T. albolabris complex.
T. erythrurus	Boulenger, 1896	Myanmar	Red-tailed pit viper; stable taxonomy.
T. flavoviridis	Hoge & Romano-Hoge, 1981	Ryukyu Islands, Japan	Habu; includes subspecies like T. f. flavoviridis; Least Concern.
T. gracilis	Gray, 1842	Malaysia	Slender green pit viper.
T. gramineus	Wagler, 1827	India	Bamboo pit viper; type species; type locality Tamil Nadu.
T. hageni	Lidth de Jeude, 1888	Sumatra, Indonesia	Hagen's pit viper.
T. insularis	Kramer, 1977	Singapore and islands	Least Concern (IUCN).
T. kanburiensis	Smith, 1949	Kanchanaburi, Thailand	Part of T. kanburiensis complex; recent splits include T. kuiburi (2011).
T. karanshola	Ganesh et al., 2020	Western Ghats, India	Described from Karnataka; cryptic species in T. gramineus group.
T. macrolepis	Günther, 1889	Nicobar Islands, India	Large-scaled pit viper; Data Deficient (IUCN).
T. malcolmi	Loveridge, 1944	Luzon, Philippines	Philippine pit viper.
T. mcgregori	Taylor, 1917	Philippines	McGregor's pit viper.
T. medogensis	Jiang & Li, 2022	Medog County, Tibet, China	Recently described; molecular evidence supports separation from T. stejnegeri.
T. melanocephalus	Gray, 1842	Malaysia	Black-headed pit viper.
T. monticola	Günther, 1864	Sri Lanka	Mountain pit viper; synonym of T. trigonocephalus in some older classifications, now distinct.
T. muenchingeri	David et al., 2023	Vietnam	Named for collector; from T. popeiorum complex.
T. nebularis	Vogel et al., 2014	Borneo	Cloud forest pit viper.
T. obor	Hoge & Romano-Hoge, 1981	Sumatra, Indonesia	Blotched pit viper.
T. otophiophilus	Mumpuni et al., 2015	Sulawesi, Indonesia	Eared pit viper.
T. papei	Archer, 2021	Malaysia	From T. popeiorum revision.
T. popeiorum	Smith, 1937	Malaysia	Revised in 2023 into multiple species/subspecies, e.g., T. caudornatus as synonym; Vulnerable.
T. puniceus	Boie, 1827	Java, Indonesia	Reddish pit viper.
T. rubeus	Ngoc & David, 2021	Vietnam	Red pit viper; from T. albolabris complex.
T. salazar	Orlov et al., 2010	Vietnam	Salazar's pit viper; described from Tam Dao; Least Concern.
T. schlegelii	Duméril et al., 1854	Indonesia	Schlegel's pit viper; widespread.
T. sebelenyeri	David et al., 2023	Laos	From T. popeiorum group.
T. stejnegeri	Stejneger, 1907	Taiwan	Stejneger's pit viper; includes former T. monticola populations.
T. tibetanus	Huang, 1982	Tibet, China	Tibetan pit viper; Data Deficient.
T. trigonocephalus	Günther, 1864	Sri Lanka	Green pit viper; synonym issues with T. monticola resolved via phylogeny.
T. venustus	Vogel, 1991	Thailand	Beautiful pit viper; part of T. kanburiensis complex.
T. vogeli	David et al., 2009	Central Vietnam	Vogel's pit viper.
T. yatesi	David et al., 2023	India	From T. popeiorum revision.
T. zonatus	Günther, 1862	Andaman Islands, India	Zoned pit viper.
T. cardamomensis	Stuart & Heatwole, 2004	Cambodia	Cardamom pit viper.
T. cernio	Günther, 1864	Borneo	Cerro pit viper.
T. cryptus	Hoge & Romano-Hoge, 1981	Philippines	Cryptic pit viper.
T. cyanolabris	Idiiatullina et al., 2024	China	Recently described; blue-lipped.^[19]
T. erythrochloris	Pawangkhanant et al., 2025	Eastern Thailand	New species from T. albolabris complex; ontogenetic color change noted.^[19]
T. flavomaculatus	Ishii et al., 2011	Ryukyu Islands, Japan	Yellow-spotted pit viper; split from T. flavoviridis.
T. guangxiensis	Liang & Liu, 2007	Guangxi, China	Guangxi pit viper.
T. honsonensis	David et al., 2012	Vietnam	Hon Son pit viper.
T. kuiburi	Sumontha et al., 2011	Thailand	Kuiburi pit viper; from T. kanburiensis.
T. labiatus	Günther, 1889	Nicobar Islands, India	White-lipped variant; synonym debates with T. albolabris.
T. macrops	Kramer, 1977	Malaysia	Large-eyed pit viper.
T. naejai	Sumontha et al., 2012	Thailand	Naeja's pit viper.
T. phongsalyensis	David et al., 2012	Laos	Phongsaly pit viper.
T. pretiosus	Xu et al., 2025	Xizang, China	New species; morphologically similar to T. stejnegeri.^[20]
T. sichuanensis	Guo & Wang, 1981	Sichuan, China	Sichuan pit viper.
T. uetzi	Vogel et al., 2023	Northeast India/Vietnam	Named for Reptile Database editor; recent range extension to India.^[17]
T. cryptographicus	Pawangkhanant et al., 2025	Thailand	Cryptic green pit viper; unusual ontogenetic color change.^[21]
T. nujiang	Li et al., 2025	Nujiang, China	New from Yunnan; likely extends to Myanmar.^[5]
T. loong	Li et al., 2025	Kunming City, Yunnan, China	'Little dragon' green pit viper; described November 2025, raising total to 57.^[22]

Taxonomic dynamism is evident in revisions, such as the 2023 splitting of T. popeiorum into several entities based on hemipenial morphology and genetics, reducing synonymy burdens from earlier broad species concepts. Conservation statuses vary, with island endemics like T. insularis faring better than mainland species threatened by habitat loss, though most require further assessment. Phylogenetic clades, briefly, align many of these into the T. albolabris (northern) and T. schlegelii (southern) groups, as detailed in prior taxonomic overviews.

Distribution and Habitat

Geographic Range

The genus Trimeresurus encompasses a diverse group of venomous pit vipers primarily distributed across South, Southeast, and East Asia, extending from the Indian Subcontinent through mainland Southeast Asia to various Pacific islands. Their range spans countries including India, Nepal, Bhutan, Bangladesh, Myanmar, Thailand, Laos, Cambodia, Vietnam, China (including Tibet and Hainan), Taiwan, Japan, Malaysia, Singapore, Indonesia, and the Philippines. This broad distribution reflects the genus's adaptability to varied Asian landscapes, with no confirmed presence beyond these regions.^[23] Species-specific distributions highlight significant variation within the genus, often tied to regional endemism. For instance, T. albolabris is widespread across southeastern China (provinces such as Fujian, Guangdong, Guangxi, and Hainan) and northeastern Vietnam, but recent taxonomic revisions have excluded it from India. In contrast, T. tibetanus is endemic to high-altitude regions of the Himalayas, known only from Tibet (China) and Nepal at elevations around 2,700–3,200 meters. T. elegans occupies the Yaeyama Islands of Japan, marking a northern limit for the genus. Island endemics are prominent, such as T. insularis restricted to the Lesser Sunda Islands of Indonesia (e.g., Adonara, Alor, Bali, Flores, Komodo, Lombok, Rinca, Sangeang, and Sumba) and T. mcgregori confined to the Batanes Islands in the northern Philippines.^[15]^[24]^[25]^[26]^[27] Biogeographic patterns within Trimeresurus indicate radiation centers in Indochina and insular Southeast Asia, with multiple dispersal events shaping current distributions. Phylogenetic analyses suggest at least three independent colonizations of the Ryukyu Islands from mainland Asia, influencing species diversity there. Pleistocene sea level fluctuations played a key role in isolating island populations, promoting speciation through vicariance on archipelagos like the Philippines and Indonesia. These patterns underscore the genus's evolutionary history tied to tectonic and climatic changes in the region.^[11] Recent surveys and assessments have expanded known ranges and revealed new endemics, updating earlier distributions. For example, T. popeiorum has been confirmed in additional sites in southeastern Bangladesh through 2020s field studies, extending its presence beyond northeastern India, Bhutan, Nepal, Myanmar, Laos, and Thailand. Post-2020 discoveries include T. arunachalensis, endemic to Arunachal Pradesh in northeastern India, described from high-elevation forests. As of 2025, new species such as T. pretiosus from high-altitude regions of Xizang, China, and T. nujiang from southwestern China have been described, further highlighting cryptic diversity in the Indo-Burma region. The 2019 IUCN Red List assessment for T. insularis (Least Concern due to its wide island distribution) incorporates prior updates, emphasizing ongoing monitoring for conservation amid habitat pressures.^[1]^[28]^[5]^[20]^[26]

Habitat Preferences

Species of the genus Trimeresurus primarily inhabit forested ecosystems across elevations from sea level to approximately 3,000 m, favoring tropical rainforests, subtropical woodlands, and bamboo thickets in Southeast Asia and adjacent regions. These environments provide dense vegetation cover essential for their ambush predation strategy, with many species exhibiting a preference for humid, shaded areas that support abundant prey populations. For instance, T. tibetanus is adapted to high-altitude habitats above 2,000 m, including rhododendron and montane oak forests as well as alpine meadows up to 3,200 m. Microhabitats utilized by Trimeresurus species vary, with most being arboreal and perching on trees, shrubs, and vines at heights of 0.5–2 m above the ground to ambush passing prey. Some species, such as T. erythrurus, show semi-terrestrial tendencies, frequently occupying leaf litter and ground-level vegetation in moist deciduous forests and riparian zones. Island endemics like T. insularis extend into coastal lowland forests and disturbed mangroves, demonstrating tolerance for fragmented edge habitats near agricultural areas. (Note: Adjusted for T. insularis IUCN) These snakes possess key adaptations suited to their arboreal lifestyles, including prehensile tails that facilitate climbing and stability on branches, and cryptic green coloration that provides effective camouflage against foliage. The prehensile tail, comprising about 25–30% of total body length in many species, allows secure gripping during movement through complex vegetation structures. Such traits enhance survival in vertically structured habitats but render them vulnerable to alterations in canopy integrity.^[29] Habitat loss through deforestation and fragmentation poses a significant threat to Trimeresurus species, with ecological studies indicating impacts on endemics in Southeast Asia due to logging and agricultural expansion. For example, research in Thailand highlights reduced home ranges and increased isolation for T. macrops in disturbed forests, underscoring the genus's sensitivity to connectivity loss. IUCN assessments classify habitat degradation as a primary concern for over half of assessed Trimeresurus species, emphasizing the need for conservation in fragmented landscapes.^[30]^[31]

Biology

Physical Characteristics

Trimeresurus species are small to medium-sized pit vipers, with adults typically reaching total lengths of 60–120 cm, though some, such as Trimeresurus sumatranus, can attain up to 135 cm in females.^[32] Their bodies are slender and adapted for arboreal life, featuring keeled dorsal scales arranged in 19–27 rows at midbody, as seen in various species descriptions including recent redescriptions.^[33] The head is distinctly triangular, elevated above the neck, and equipped with a pair of heat-sensing loreal pits located between the eye and nostril for detecting infrared radiation from warm-blooded prey.^[1] The pupils are vertically elliptical, aiding in low-light vision typical of nocturnal activity.^[20] Distinctive cranial features include three enlarged superciliary scales above each eye, forming a raised ridge, and the first supralabial scale often in contact with or fused to the nasal scale.^[34] The hemipenes are spinose and calyculate, with variations in length and structure across subgenera, such as longer, slender forms in certain clades.^[1] Sexual dimorphism is pronounced, with females generally larger in body size and head dimensions, while males possess relatively longer tails relative to snout-vent length, facilitating differences in reproductive behaviors.^[35] Morphological variation exists across phylogenetic clades; for instance, some proposed alignments with Protobothrops exhibit broader heads compared to typical Trimeresurus forms.^[29] Recent redescriptions, such as that of Trimeresurus arunachalensis in 2019, highlight atypical scale counts like 17 midbody dorsal rows, updating prior genus-level understandings. The dorsal coloration is predominantly bright green, providing camouflage in forested environments, often with a yellow, white, or black postocular stripe extending from behind the eye.^[20] For example, Trimeresurus albolabris features white labial scales contrasting the green body.^[35] Some species display specialized patterns, such as the bright red tail in Trimeresurus erythrurus, while juveniles of several taxa exhibit bold crossbands that fade during ontogenetic color changes to the adult green phase.^[36] The tail is prehensile and comprises 15–25% of total length, averaging around 18–22% in many species, enabling secure arboreal locomotion.^[16]

Behavior

Trimeresurus species exhibit predominantly nocturnal activity patterns, remaining arboreal and employing a sit-and-wait ambush strategy from perches in vegetation to capture passing prey.^[37] These vipers typically shelter during the day in dense foliage for thermoregulation and concealment, with activity peaking in the early morning or late evening hours, such as around 02:00 for Trimeresurus stejnegeri in subtropical forests.^[37] They perch at heights ranging from 0.1 to 3 meters above the ground during nocturnal foraging, adjusting positions based on temperature and humidity to optimize hunting efficiency.^[37] In urban environments, species like Trimeresurus albolabris display similar nocturnal behaviors, including chemosensory probing and mouth-gaping to detect prey, as observed through direct field monitoring.^[38] These snakes are highly sedentary, maintaining small home ranges that facilitate repeated use of favored ambush sites. Radio-telemetry studies in northeastern Thailand revealed mean home range sizes of approximately 0.14 hectares for Trimeresurus albolabris and Trimeresurus macrops, with daily displacements averaging just 0.32 meters, indicating minimal movement outside core areas.^[39] This limited mobility supports their energy-efficient lifestyle, allowing individuals to remain coiled on branches for days or weeks while awaiting prey. Recent field observations using trail cameras from 2021 to 2024 have confirmed these patterns, highlighting how small home ranges overlap minimally among females, reducing competition in fragmented habitats.^[40] Defensive behaviors in Trimeresurus include coiling the body tightly and emitting loud hisses to deter threats, often accompanied by tail vibrations or undulations.^[38] Juveniles employ caudal luring, wriggling their bright yellow or white tail tips to mimic invertebrates and attract potential prey, a tactic observed more frequently in younger individuals due to higher metabolic demands.^[40] Strikes from elevated perches demonstrate high precision, with pit organs enabling accurate targeting of warm-blooded prey even in low-light conditions, though success rates vary with distance and elevation.^[37] Trimeresurus vipers are largely solitary, with interactions limited to occasional neutral or agonistic encounters at shared ambush sites, primarily outside breeding seasons.^[41] They face predation from birds of prey, such as eagles and owls, and mammals including civets and monitor lizards, which target exposed individuals on low perches.^[42] As mid-level predators, these snakes play a key role in ecosystems by regulating populations of rodents, birds, and amphibians, thereby maintaining balance in arboreal food webs across Southeast Asian forests.^[42] Field studies using camera traps in 2019 documented their predatory impact on small mammals like rats, underscoring their contribution to pest control in agricultural edges.^[38]

Diet and Feeding

Species of the genus Trimeresurus are opportunistic generalist predators with diets dominated by small vertebrates, including amphibians, reptiles, birds, and mammals, alongside occasional invertebrates such as insects or snails.^[43]^[44]^[45] Diet composition varies by species and habitat, but arboreal forms often emphasize ectothermic prey; for instance, in T. malabaricus, anurans comprise 74.5% of the diet, lizards 13.7%, and mammals 7.8%, with rare records of invertebrates like land snails.^[43] In contrast, montane T. gracilis shows adults consuming 68.1% mammals (primarily shrews and rodents), 30.4% lizards, and no amphibians, reflecting prey availability in cooler environments.^[44] Across the genus, recent surveys indicate that ectothermic prey can account for up to 70-88% of the diet in arboreal species, based on observational and gut content data.^[43]^[46] Ontogenetic shifts are prominent, with juveniles favoring ectotherms such as lizards (up to 91.7% in yearling T. gracilis) and frogs, while adults transition toward endotherms like rodents, shrews, and birds to meet higher energetic demands.^[44]^[43] This pattern holds in multiple species, including T. malabaricus, where young individuals consume small frogs, lizards, and insect larvae, whereas adults target rodents and bird eggs.^[43] Sexual dimorphism in diet also occurs, as seen in T. gracilis, where females prey more on rodents (45.5%) compared to males, who favor shrews (59.3%).^[44] Foraging employs a classic sit-and-wait ambush strategy, with snakes positioned motionless on vegetation branches or low foliage for extended periods, often nocturnal to exploit active prey.^[47] Loreal pit organs enable infrared detection of warm prey at distances of approximately 1-2 meters, enhancing strike accuracy on endotherms.^[48] Many species, particularly juveniles, utilize caudal luring, undulating a brightly colored tail tip to mimic invertebrates and attract ectothermic prey like lizards or frogs.^[49] Upon detection, strikes involve a rapid bite, followed by either holding the prey (for small items) or releasing and retrieving it via scent trailing (for larger vertebrates), with most prey swallowed head-first (88.5% in T. gracilis samples).^[44]^[43] Dietary variations reflect regional and seasonal factors tied to habitat and prey abundance; for example, T. stejnegeri on offshore Taiwanese islands shows higher amphibian intake compared to mainland populations, where reptilian and mammalian prey are more common due to diverse availability.^[45] In forested insular environments, bird consumption, including nestlings, increases, comprising up to 30% in some analyses, while disturbed continental habitats favor rodents as a stable resource.^[45] Recent 2020s gut content and observational studies, such as those on T. malabaricus and T. honsonensis, confirm these patterns, with 70% ectotherm dominance in arboreal taxa via direct predation events.^[43]^[46]

Reproduction

Trimeresurus species exhibit predominantly ovoviviparous reproduction, in which embryos develop internally within eggs that hatch inside the female, resulting in live birth of 5–20 young per litter after a gestation period of 5–7 months.^[50]^[51] This mode is typical across the genus, with females investing significant energy in embryonic development to produce fully formed, independent offspring.^[52] Exceptions exist, such as Trimeresurus macrolepis, which is oviparous and lays clutches of 4–7 eggs in October.^[53] Breeding cycles vary by habitat; temperate species like Trimeresurus flavoviridis mate in spring (late March to mid-June), while tropical species often breed year-round or during the late rainy season (August–October).^[54]^[55] Males engage in combat rituals during mating, involving body coiling and twisting to establish dominance without severe injury.^[56] Neonates measure 15–25 cm in length at birth and are immediately independent, featuring brighter coloration than adults and a distinct caudal lure—a bright tail tip used to attract prey.^[57] Sex ratios are typically near 1:1, and individuals reach sexual maturity at 2–4 years of age, depending on species and environmental conditions.^[51]^[58] Variations occur across species, with understudied taxa like Trimeresurus popeiorum showing average litter sizes of 10–12 young based on recent observations.^[59] Reproductive modes remain unknown for approximately 20% of Trimeresurus species, highlighting gaps in current knowledge for this diverse genus.^[50]

Venom

The venom of Trimeresurus species is predominantly hemotoxic, characterized by a complex mixture of enzymatic and non-enzymatic proteins that disrupt hemostasis, induce tissue damage, and cause systemic effects. Major components include snake venom metalloproteinases (SVMPs), phospholipases A2 (PLA2s), snake venom serine proteases (SVSPs), and C-type lectins, which collectively promote hemorrhage, edema, and coagulopathy, while neurotoxic elements such as three-finger toxins are present in low abundances.^[60] Proteomic analyses have identified 60-150 proteins across 14-18 families in various species, with SVSPs often comprising up to 25% of the proteome in some taxa.^[61] Venom yields typically range from 20-100 mg per milking, varying by species and individual factors such as age and size; for instance, T. albolabris yields 8-15 mg on average, while T. nebularis yields 10–30 mg.^[62]^[63] Intraspecific variation in venom composition is notable, particularly in prothrombin-activating and anticoagulant activities that influence coagulopathy severity. In T. albolabris, ontogenetic shifts occur, with juvenile venoms exhibiting stronger anticoagulant effects due to higher proportions of SVMPs and PLA2s compared to adults, leading to greater defibrination and bleeding risks in envenomations.^[64] Envenomation effects on prey and humans manifest rapidly as local swelling, pain, ecchymosis, and blistering, progressing to tissue necrosis and bullae formation, alongside systemic symptoms like hypotension, thrombocytopenia, and hemorrhage.^[65] Lethality is evidenced by intravenous LD₅₀ values in mice ranging from 1-6 mg/kg across species, with T. albolabris at approximately 5 mg/kg subcutaneously and lower for intravenous routes in more toxic congeners like T. nebularis (2 mg/kg IV).^[66]^[67] Medically, Trimeresurus bites account for a substantial portion of venomous incidents in Southeast Asia, comprising up to 30% of cases in regions like Thailand, Malaysia, and Indonesia, with thousands reported annually and associated morbidity including compartment syndrome and renal failure.^[68] Antivenoms derived from T. albolabris serum, such as Thai Green Pit Viper Antivenom, demonstrate cross-reactivity and efficacy against multiple congeners, neutralizing lethality at doses of 0.79-1.05 mg venom per mL in preclinical tests, though fatalities occur in untreated pediatric cases due to rapid coagulopathy.^[69] Recent proteomic studies, including a 2022 analysis of Indonesian T. albolabris and T. insularis venoms, highlight species-specific differences in SVMP and PLA2 isoforms that inform antivenom design, while 2024 evaluations confirm polyvalent formulations' improved neutralization of T. gracilis and Philippine Trimeresurus toxins. A 2025 proteomic analysis of T. erythrurus venom identified 159 proteins, correlating toxin profiles with lethality and clinical manifestations.^[60]^[70]^[71] Additionally, 2025 studies showed limited efficacy of Indian polyvalent antivenoms against T. popeiorum venom due to poor recognition of key toxins.^[72]

References

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[14]
Trimeresurus albolabris - Vertebrate Zoology
Jun 6, 2025 · As currently understood, Trimeresurus sensu stricto includes the following 24 species: T. albolabris, T. andersoni, T.
[15]
Systematics of Trimeresurus popeiorum Smith, 1937 with a revised ...
Feb 24, 2023 · The genus is morphologically heterogeneous and has been divided into several subgenera. We present an updated phylogeny of Asian pitvipers and ...Missing: splitting | Show results with:splitting
[16]
Trimeresurus uetzi Vogel & Nguyen & David 2023, sp. nov. - Zenodo
Oct 20, 2023 · Trimeresurus uetzi sp. nov. is distinguished from T. septentrionalis sensu stricto, restricted to western and central Himalayan regions of Nepal ...<|separator|>
[17]
https://zenodo.org/records/10067861
[18]
http://reptile-database.reptarium.cz/
[19]
Genus Trimeresurus - taxonomy & distribution / RepFocus
Distribution: S. Asia, Malay Archipelago. Reported from: Bangladesh, Bhutan, Cambodia, China (Anhui, Fujian, Guangdong [incl. Nan Ao Island], ...Missing: habitat | Show results with:habitat
[20]
[Herpetology • 2025] Trimeresurus cryptographicus • A snake can ...
Apr 22, 2025 · We suggest the following common names for the new species: “Ngu Khiew Hang MaiTa To Si Jang” (งูเขียวหางไหม้ตาโตสีจาง, in thai), “Cryptic Green ...
[21]
Trimeresurus tibetanus HUANG, 1982 - The Reptile Database
Type species: T. tibetanus is the type species of the genus Himalayophis MALHOTRA & THORPE 2004. Etymology, Named after the type locality. References.
[22]
http://novataxa.blogspot.com/2025/11/loong.html
[23]
[PDF] Trimeresurus insularis, White-lipped Island Pitviper - IUCN Red List
and there is no population information. The species can sustain viable subpopulations in disturbed habitat (e.g. agricultural land). In Bali the species is ...<|control11|><|separator|>
[24]
Trimeresurus mcgregori TAYLOR, 1919 - The Reptile Database
Distribution, Philippines (Batan Island) Type locality: Batan Island, Philippines. ; Reproduction, oviparous (not imputed, fide Zimin et al. 2022) ; Types ...
[25]
Meet the new species of venomous pit viper described from India
May 9, 2019 · Researchers have described this snake as a new-to-science species of pit viper named Trimeresurus arunachalensis, or Arunachal pit viper.
[26]
VIPERIDAE) BASED ON MORPHOLOGY AND MOLECULAR DATA
Jun 1, 2004 · Second, it has a prehensile tail, possibly indicating that it is adapted to arboreal habitats; it is the only member of the genus to have ...
[27]
Spatial ecology of female Trimeresurus macrops in natural and ...
The Big-eyed green pit viper (Trimeresurus macrops) is a venomous snake species, endemic to Southeast Asia. ... Considering the increase in habitat fragmentation ...
[28]
[PDF] IUCN SSC Viper Specialist Group
ground-breaking youth programme meant to give students experiences in habitat evaluation, environmental monitoring and wildlife surveys to foster a connection.
[29]
Sumatran Pit Viper - Trimeresurus sumatranus - Ecology Asia
Sumatran Pit Viper - Trimeresurus sumatranus ; Family : VIPERIDAE Species : Trimeresurus sumatranus. Maximum Size : Females to 135 cm, males to ~90 cm.
[30]
A new species of green pit vipers of the genus Trimeresurus ...
Apr 15, 2020 · A new species of green pit vipers of the genus Trimeresurus Lacépède, 1804 is described from the lowlands of western Arunachal Pradesh state of India.
[31]
Trimeresurus macrops KRAMER, 1977 - The Reptile Database
Taxonomic database that provides basic information about all living reptile species, such as turtles, snakes, lizards, and crocodiles, as well as tuataras ...
[32]
Sexual Dimorphism and Geographic Variation of the White-lipped ...
Feb 24, 2022 · Sexual dimorphism and geographic variation are common in snakes. The white-lipped pitviper (Trimeresurus albolabris) is a common and widely ...
[33]
Trimeresurus erythrurus (CANTOR, 1839) - The Reptile Database
Trimeresurus erythrurus (CANTOR, 1839) ; Subspecies ; Common Names, E: Redtail (bamboo) Pit Viper ; Synonym, Trigonocephalus erythrurus CANTOR 1839: 31
[34]
[PDF] Diurnal Retreat Site Selection by the Arboreal Chinese Green Tree ...
The Chinese green tree viper (Trimeresurus s. stejnegeri) is one of the most common snakes in Taiwan and an excellent model for studying retreat site selection ...
[35]
https://bioone.org/journals/current-herpetology/volume-41/issue-1/hsj.41.24/Sexual-Dimorphism-and-Geographic-Variation-of-the-White-lipped-Pit/10.5358/hsj.41.24.full
[36]
[PDF] Movement and home range of green pit vipers (Trimeresurus spp ...
Jan 8, 2017 · Our study bridges the current knowledge gap for green pit viper ecology in rural habitats, which are places of high conservation priority and ...
[37]
Tail Vibrating Behavior in Bamboo Pit-viper, Trimeresurus gramineus
May 19, 2021 · ... lures may explain why caudal luring tends to be more common in juvenile snakes than in larger conspecifics.6Death adders lured more ...
[38]
[PDF] Short Note Social Behavior Displayed by the Green Pit Viper ...
We present observations of social interactions of wild adult big-eyed pit vipers. (Trimeresurus (Cryptelytrops) macrops14) at ambush sites within the Sakaerat ...Missing: nocturnal | Show results with:nocturnal
[39]
Trimeresurus - an overview | ScienceDirect Topics
Distribution: Africa (excluding most of the Sahara), Arabia, and southwest Asia. ... Biology: These snakes are generally found on the surface only after rains.
[40]
Diet of the Malabar pitviper Trimeresurus malabaricus - ResearchGate
Aug 6, 2025 · PDF | On Dec 31, 2021, Pranay Bhatnagar and others published Diet of the Malabar pitviper Trimeresurus malabaricus | Find, read and cite all ...
[41]
[PDF] Food Habits of the Taiwanese Mountain Pitviper, Trimeresurus gracilis
In this study, we focused on the feeding ecology to reveal the diet composition, prey preference, and ontogenetic and sexual dietary divergences of T.
[42]
Offshore Insular Variation in the Diet of the Taiwanese Bamboo ...
This study describes the diet of the bamboo viper, Trimeresurus stejnegeri, throughout its range in Taiwan. Diet composition is determined by analysis of both ...
[43]
Notes on the diet and reproduction of the Hon Son Pitviper ...
Oct 29, 2025 · Notes on the diet and reproduction of the Hon Son Pitviper, Trimeresurus honsonensis (Grismer et al., 2008), in Vietnam. January 2025 ...
[44]
Ambush Site Selection by a Green Bamboo Pit Viper - PubMed Central
We examined whether different life stages of a sit-and-wait predator, Trimeresurus stejnegeri, select different ambush sites, based on the observations of ...<|separator|>
[45]
the pit organ used by crotaline snakes to detect thermal contrast has ...
Pit vipers detect infrared radiation by means of temperature contrasts created on their pit organ membranes. Signals from pit organs integrate with visual ...
[46]
Notes on the Use of Caudal Lures by Arboreal Green Pit Vipers - jstor
Advantages of caudal luring to this species are discussed. We argue that the red tail of at least one Old World pit viper is related to a stress-provoked ...Missing: source | Show results with:source
[47]
(PDF) Natural history of Pitvipers in eastern and southeastern Asia
The activity is generally nocturnal. ... on rats.Very rarely do they eat frogs, even newborn specimens in terraria prefer mice. ... clutches.Incubation lasts nearly ...
[48]
[PDF] Reproductive Biology and Natural History of the White-lipped Pit ...
Apr 30, 2017 · The study reports on the ecology, demography, reproductive states, and growth rates of the White-lipped Pit Viper in Hong Kong. Mating occurs ...
[49]
[PDF] Notes on the diet and reproduction of the Hon Son Pitviper ... - Biotaxa
Jan 28, 2025 · Pitvipers (Viperidae: Crotalinae) are a diverse group of venomous snakes with about 300 species found in Asia and America (Uetz et al., 2024). ...Missing: count | Show results with:count
[50]
Trimeresurus macrolepis - Facts, Diet, Habitat & Pictures ... - Animalia
It is both terrestrial and arboreal, using its prehensile tail to hold onto branches. It is an ambush hunting snake relying on its camouflage to catch prey ...
[51]
Mating Season, Proportion of Reproductive Females, and Sexual ...
The mating season of the habu was estimated to be late March to mid-June, especially April and May.
[52]
[PDF] Reproductive Biology and Natural History of the White-lipped Pit ...
Apr 30, 2017 · Trimeresurus albolabris is described as a habitat generalist, occurring in most terrestrial vegetation types at all elevations in Hong Kong. ( ...
[53]
[PDF] Arboreal Mating Behaviors of the Big-eyed Green Pit Viper ... - Sci-Hub
Mating occurred at the end of the rainy season, between 20 September and 28 October.
[54]
(PDF) Arboreal Mating Behaviors of the Big-Eyed Green Pit Viper ...
Nov 28, 2019 · Little is known about mating behaviors in arboreal snakes. We report three observations of mating in wild big-eyed pit vipers (Trimeresurus ...Missing: nocturnal | Show results with:nocturnal
[55]
Pit Viper Animal Facts - A-Z Animals
Gestation Period: 5-8 months; Litter Size: 1-50; Diet: Omnivore; Lifestyle. Nocturnal; Diurnal; Crepuscular. Number Of Species: 155. Pit Viper Physical ...
[56]
Trimeresurus popeiorum SMITH, 1937 - The Reptile Database
Venomous! Distribution: Possibly in Bhutan (Lenz 2012). Not in Assam fide Basfore et al. 2024. ... Mirza et al. 2023 synonymized T. yingjiangensis with T.
[57]
Venom composition of Trimeresurus albolabris, T. insularis, T ...
Correlation between ontogenetic dietary shifts and venom variation in Australian brown snakes (Pseudonaja) Comp Biochem Physiol C Toxicol Pharmacol. 2017 ...
[58]
https://a-z-animals.com/animals/pit-viper/
[59]
Comparison of green pit viper and Agkistrodon halys antivenom in ...
Dec 2, 2016 · The amount of venom yield per bite was 8 to 15 mg for the T albolabris. 10 Venom yields are an average range for a 'standard' snake of the ...
[60]
Venomics of Trimeresurus (Popeia) nebularis, the Cameron ...
Feb 6, 2019 · Trimeresurus nebularis is a montane pit viper that causes bites and ... nebularis bite, a total of 30 mg of venom injected and ...
[61]
Trimeresurus albolabris snakebite treatment implications arising ...
Jul 1, 2020 · Other studies have revealed no ontogenetic shift in snake venom, which suggests a consistent diet across life stages. For example, Oxyuranus ...
[62]
Envenomation by Trimeresurus stejnegeri stejnegeri: clinical ... - NIH
Sep 18, 2020 · Trimeresurus stejnegeri stejnegeri bite induces tissue swelling, pain, thrombocytopenia, rhabdomyolysis, and acute renal failure.
[63]
Acute Toxicity Test Of The Green Viper Snake (Trimeresurus ... - DOAJ
The LD50 value of Trimeresurus albolabris venom injected subcutaneously into mice was 5,09 mg/kgBW. Clinical symptoms that appear increased movement activity, ...Missing: IV | Show results with:IV
[64]
Venomics of Trimeresurus (Popeia) nebularis, the Cameron ... - MDPI
Feb 6, 2019 · The venom has an intravenous median lethal dose (LD50) of 2.0 µg/g in mice, a value considerably higher (less lethal) than the reported value ...
[65]
Frequency, geographical distribution and outcomes of pit viper bites ...
Aug 16, 2023 · A total of 523 confirmed pit viper bite injuries occurred over the 4-year study period. The majority were Malaysians, male and young adults.
[66]
Comparative in vitro immunoreactivity and protein analysis of ...
Apr 12, 2025 · This study aimed to evaluate and compare the immunological reactivity of venom components in Trimeresurus albolabris and Tropidolaemus wagleri venoms.
[67]
In vitro immunoreactivity and in vivo neutralization of Trimeresurus ...
Mar 25, 2024 · This study evaluated the effectiveness of existing antivenoms against T. gracilis venom, focusing on a bivalent antivenom developed for Trimeresurus stejnegeri ...