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Advanced Photon Source

The Advanced Photon Source (APS) is a synchrotron radiation light source facility located at Argonne National Laboratory in Lemont, Illinois, operated by the U.S. Department of Energy's Office of Science, that produces the world's brightest beams of X-rays for scientific research across disciplines including materials science, biology, chemistry, and physics. It consists of a 6 GeV electron storage ring with a circumference of approximately 1,104 meters and a design current of 200 mA, designed to generate high-brilliance X-rays using bending magnets and insertion devices, and serving as one of five major X-ray light sources in the United States. Construction began with groundbreaking on June 4, 1990, and the facility achieved first light on March 26, 1995, marking it as the first high-energy third-generation synchrotron in the U.S., with full research operations commencing in the fall of 1996. Historically, the APS has supported approximately 5,500 scientists annually from universities, industry, and national laboratories, who conduct over 6,000 experiments each year at its 72 beamlines, with access provided free for non-proprietary research and on a cost-recovery basis for proprietary work; post-upgrade operations are resuming in 2025. Over its history, the facility has enabled more than 37,000 peer-reviewed publications and contributed to three Nobel Prizes in Chemistry—in 2009 for ribosome structure, 2012 for G-protein-coupled receptors, and 2024 for —while advancing discoveries in , , , and . The APS completed a major upgrade project in 2025, replacing its original with a new multibend achromat lattice operating at 6 GeV and 200 mA, with first s achieved in April 2024 at a total project cost of $815 million, delivering beams up to 500 times brighter than before and establishing it as the first fourth-generation in the U.S. Post-upgrade, the APS achieved a world-record horizontal emittance of 33 pm·rad in 2025, reducing emittance to unprecedented levels for enhanced and , enabling time-resolved studies of ultrafast processes and atomic-scale that were previously unattainable. With over 450 staff members supporting operations, the upgraded APS continues to drive transformative science, including breakthroughs in technologies and biomedical applications.

History

Development and construction

The Advanced Photon Source (APS) originated in the early 1980s as part of a U.S. initiative to develop third-generation sources capable of producing high-brilliance s for advanced scientific research. A -sponsored planning study in March 1984 recommended the construction of a dedicated high-brilliance facility, leading to the selection of as the host site in . Conceptual design efforts followed, with Argonne publishing a 6-GeV Source report in February 1986 and upgrading to a 7-GeV Advanced Photon Source Report in April 1987, emphasizing a optimized for hard production. Key milestones advanced rapidly in the late 1980s. In May 1988, the approved the project start, authorizing the transition from conceptual to full development. The first construction funds were released on October 1, 1989, followed by groundbreaking on June 4, 1990, which marked the beginning of site preparation and building on Argonne's 80-acre campus. Funding came primarily from the Office of Science, with a total construction cost of approximately $467 million, supporting the design of a 7-GeV storage ring with a circumference of 1,104 meters to generate intense hard beams. Construction faced significant logistical challenges, including the integration of a linear accelerator, booster synchrotron, and the main within the constrained site, requiring over 2 million man-hours from 72 subcontractors. An aggressive safety program ensured no serious injuries, achieving an accident rate one-quarter of the U.S. industrial average, while managing extensive materials such as 54,600 cubic yards of and 5,800 tons of for shielding and support structures. By October 1993, linac commissioning began with a 50-MeV beam, paving the way for storage ring integration, and the project completed ahead of schedule with first light achieved on March 26, 1995.

Commissioning and early operations

The commissioning of the Advanced Photon Source (APS) began with the successful storage of the first 4.5 GeV electron beam in the on March 25, 1995, followed by the detection of the first bending magnet radiation on March 26, 1995. This milestone marked the initial activation of the at . Shortly thereafter, on August 9, 1995, the first undulator beam was produced, exceeding specifications for brightness and spectral performance. By early 1996, the facility achieved key operational parameters, including the first 100 mA stored electron beam on January 12 and the operation of an undulator with this current on January 26. In July 1996, the first 7 GeV beam was stored, reaching 100 mA the following day, aligning with the design goals for high-energy, high-current operation to generate intense . The official dedication ceremony occurred on May 1, 1996, highlighting the facility's readiness for scientific use. Initial beamline installations focused on insertion devices, including undulators and wigglers, to produce tunable beams from generated by the accelerated electrons (or positrons). These devices were installed in the 35 straight sections of the 40-sector , enabling the extraction and utilization of high-brilliance X-rays for experiments. The user program launched in fall 1995 with the first experiments, rapidly expanding as s became operational. By 2000, the APS served over 2,000 unique users annually, supporting a diverse range of studies. Throughout its early years into the mid-2000s, the APS maintained high operational reliability, averaging 95% availability for scheduled beam time, which supported consistent user access despite ongoing expansions and optimizations. This uptime was achieved through robust accelerator controls and feedback systems, ensuring stable beam parameters essential for precise X-ray experiments.

Facility design

Accelerator complex

The Advanced Photon Source (APS) accelerator complex consists of a three-stage system designed to generate high-energy beams for production. The initial stage is a 450 MeV linear accelerator (linac) that provides injection into the subsequent rings. This is followed by a 6 GeV booster , which ramps up the beam energy over approximately one-third of a second at a 2 Hz repetition rate. The final stage is the main , a 1,104-meter circular accelerator that maintains the beam at nominal parameters for extended periods. Key components of the complex include 40 straight sections in the , which accommodate insertion devices such as undulators and wigglers to enhance output. The features hundreds of magnets for beam bending, distributed across its 40 sectors, along with and sextupole magnets for focusing and correction. Extensive vacuum systems maintain an of approximately 10^{-10} to minimize beam scattering and ensure stability. The complex now operates with beams following the 2023-2024 , which eliminated the need for production due to the adoption of swap-out injection. The infrastructure encompasses a 200,000 experiment hall that houses 72 , enabling diverse experimental setups around the . Utilities include cryogenic cooling systems for superconducting insertion devices and magnets, ensuring low-temperature operation for high-performance components. shielding, consisting of walls and beamline hutches, along with safety interlocks and monitoring, protects personnel and the environment from high-energy . The facility is situated on the 1,500-acre Argonne National Laboratory campus, approximately 25 miles southwest of , , integrating seamlessly with broader laboratory operations. The accelerator operates at a nominal beam energy of 6 GeV with a stored current of 200 mA, optimized for generating intense across a wide spectral range.

Storage ring and beamlines

The storage ring of the Advanced Photon Source (APS) is a fourth-generation synchrotron light source employing a multibend achromat lattice with 40 sectors, each alternating a straight section and multiple dipole bends to maintain the electron beam orbit. The ring has a circumference of 1,104 meters and operates with 6 GeV electrons stored at 200 mA, enabling the production of synchrotron radiation through bending magnets and insertion devices. Electrons are injected from the booster synchrotron into the ring using swap-out injection, where they circulate for hours while emitting X-rays. This design optimizes low emittance for high-brightness beams, achieving a horizontal emittance of approximately 33 pm·rad. Insertion devices are installed in 35 of the 40 straight sections, each 4.8 meters long, to generate intense, tunable beams. The APS features 29 undulators, primarily hybrid permanent magnet types with periods of 2.8 to 3.3 cm, and 11 wigglers, including superconducting and multipole variants, which collectively produce photons ranging from wavelengths to hard s exceeding 100 keV. Undulators deliver coherent, high-brightness radiation for applications requiring fine , while wigglers provide higher for broader spectra and studies. The post-upgrade peak brightness reaches up to $5 \times 10^{20} photons/s/mm²/mrad²/(0.1% BW) at a 1 wavelength, establishing the APS as the world's leading source for hard research. The network branches from the across 35 sectors in the experimental hall, with each sector supporting 1 to 3 s for a total of 72 operational stations. X-rays from insertion devices and bending magnets are transported via front ends equipped with high-heat-load absorbers, filters, and shutters to protect downstream and select specific energies while managing power loads up to several kilowatts. These front ends include diagnostic components like beam position monitors to ensure alignment. To maintain beam quality, sophisticated feedback systems correct the in , achieving position stability at the micron level (typically 1–2 μm rms over 1–100 Hz frequencies), which is critical for high-resolution experiments.

Operations

Beam production and synchrotron radiation

The electron beam for the Advanced Photon Source is produced in a linear accelerator (linac) that accelerates bunches to an energy of 450 MeV before injection into the positron accumulator ring (PAR). From the PAR, the beam is transferred to the booster synchrotron, where it is ramped up to 6 GeV over approximately 500 ms, with cycles adjusted for the upgraded system; full filling to operational current typically occurs over about without continuous injection. Swap-out injection from the booster maintains a stable circulating current of 200 mA in the by replacing spent bunches with fresh ones, enabling uninterrupted experiments while preserving the low emittance required for fourth-generation performance. In the 1.1 circumference , the relativistic electrons follow a closed defined by a hybrid multibend achromat (HMBA) with 280 magnets, compelling the charged particles to accelerate perpendicular to their velocity and emit forward in a narrow tangent to the . This arises from the classical electromagnetic fields of the accelerated charges, producing a continuous with peaking near the critical E_c, given by E_c = \frac{3}{2} \frac{\hbar c \gamma^3}{\rho}, where γ is the Lorentz factor (γ ≈ 11,700 for 6 GeV electrons), ħ is the reduced Planck's constant, and c is the speed of light; for the APS dipoles, this yields E_c ≈ 19.5 keV, with significant photon flux extending to higher energies, maintained similar to pre-upgrade via adjusted bending fields and radii. The from bending magnets offers a broad, untunable suitable for white-beam applications, extending up to several times the critical with most below 30 keV. In contrast, insertion devices such as undulators enhance by arranging periodic s to induce coherent oscillations in the , resulting in sharp peaks tunable by adjusting the device gap and thus the undulator K = (e B_0 λ_u)/(2 π m c^2), where B_0 is the peak and λ_u is the period length. The on-axis at these peaks scales with K^2 and the number of periods N_u, enabling from soft X-rays to beyond 30 keV depending on the specific undulator , with the delivering up to 500 times higher . The circulating beam experiences energy loss per turn due to synchrotron radiation, on the order of hundreds of keV, which is restored by a superconducting RF system operating at 352 MHz with a total accelerating voltage of approximately 6.4 across multiple cavities to maintain stability and compensate for . Beam lifetime in the ring is approximately 4-6 hours, dominated by Touschek scattering—intra-beam collisions that eject particles from the bunch due to the high —and mitigated by , which restores transverse emittance but contributes to overall loss; residual gas provides a minor additional limit under conditions.

User access and experiments

The Advanced Photon Source operates a robust user program that enables researchers worldwide to access its facilities through a competitive, peer-reviewed process managed via the Universal Proposal System (UPS), a collaborative platform developed by multiple national laboratories. Proposals are reviewed by Beam Time Allocation Committees, with successful applicants allocated beam time based on scientific merit and facility availability. In a typical year, the APS serves approximately 5,500 scientists, who conduct over 6,000 experiments utilizing around 5,000 scheduled beam hours at its 72 beamlines. This program supports a diverse community, including efforts to engage underrepresented groups in science through targeted and inclusive policies. Experiments at the APS are conducted during three annual run cycles, each lasting approximately three to four months, with intervening shutdown periods for and upgrades. The facility achieves a minimum uptime of 97% for and availability, defined as the hours when beam shutters are open and stored current exceeds 50 mA, divided by scheduled delivery hours. Since the 2024 upgrade, operations have utilized swap-out injection mode to maintain stable beam flux and low emittance by periodically replacing bunches in the without interrupting user experiments. Safety is paramount in user operations, with protocols enforced through the Experiment Safety Assessment Form (ESAF), which must be submitted at least 14 days in advance for onsite experiments to identify hazards such as radioactive materials, cryogens, high voltage, and lasers. All personnel accessing the experiment hall require dosimetry for radiation monitoring and must complete General Employee Radiation Training (GERT), along with sector-specific orientations covering access controls via photo badges and cardkey systems. Additional training is mandatory for handling hazardous materials, ensuring compliance with ALARA (As Low As Reasonably Achievable) principles to minimize exposure. Support facilities enhance experiment efficiency, including on-site laboratories through the Experimental Support Services (ESS) for sample preparation tasks like , purification, and solid processing. Remote access options, expanded significantly post-2020 to accommodate virtual participation amid global travel restrictions, allow users to control beamlines via NoMachine cloud servers and retrieve data through transfer services. Data management and beamline operations are facilitated by the Experimental Physics and Industrial Control System (EPICS), providing real-time monitoring and automation for experiment execution. As of October 2025, 51 beamlines are accepting users, enabling advanced studies leveraging the upgraded source's enhanced and flux.

Scientific impact

Applications in research

The Advanced Photon Source (APS) supports a suite of core X-ray techniques that enable atomic- and nanoscale investigations across scientific disciplines. These include X-ray diffraction for determining crystalline structures, small- and for probing nanoscale morphologies and dynamics, (such as XANES and EXAFS) for analyzing electronic and local atomic environments, and X-ray imaging modalities like microtomography, which achieves spatial resolutions down to 1 μm for three-dimensional visualization of internal structures. These techniques leverage the APS's high-brilliance to provide non-destructive, high-throughput data collection, often in operando conditions to capture real-time processes. In , APS beamlines facilitate detailed studies of and advanced processes. For instance, researchers have used time-resolved and to observe lithium-ion dynamics within electrodes during charge-discharge cycles, revealing degradation mechanisms that inform the of longer-lasting lithium-ion batteries. Similarly, in additive , high-energy and have elucidated microstructures in 3D-printed alloys, such as how magnetic fields influence grain orientation in stainless steels to enhance mechanical properties. These applications underscore the APS's role in optimizing material performance for sustainable technologies. Biological sciences benefit from APS capabilities in and imaging, particularly for and . Protein crystallography at dedicated beamlines like those in Sector 19 has enabled the determination of thousands of macromolecular structures, aiding the rational design of therapeutics by visualizing protein-ligand interactions at atomic resolution. In neuroscience, phase-contrast imaging supports by providing high-contrast, non-destructive 3D reconstructions of neural tissues, complementing chemical analysis of trace elements to study connectivity and pathology. In and , the APS excels at investigating reaction mechanisms and contaminant behaviors under realistic conditions. Operando has been applied to monitor catalyst structures during reactions, such as gold nanoparticles oxidizing , providing insights into active sites for emission control technologies. For pollutant studies, techniques like HERFD-XANES enable precise speciation of elements like in mine wastes, assessing and mobility to guide remediation strategies. Industrial applications leverage APS X-rays for quality assurance and failure diagnostics in high-tech sectors. In electronics, synchrotron-based imaging and spectroscopy support failure analysis of power devices, identifying defects in wide-bandgap semiconductors like GaN to improve reliability in extreme environments. For additive manufacturing, real-time tomography ensures quality control by detecting voids and microstructural flaws in printed components, accelerating certification for aerospace and automotive uses. During the (2020-2021), the APS played a pivotal role in efforts, with 224 crystal structures of proteins—including the —determined between January 2020 and September 2021 to guide design and development, such as stabilizing prefusion conformations for and vaccines. The facility's upgrade, now operational, boosts brightness by up to 500 times, enhancing resolution and speed for such time-sensitive interdisciplinary research.

Notable discoveries and awards

The Advanced Photon Source (APS) has contributed to three Nobel Prizes in Chemistry, recognizing groundbreaking structural biology research enabled by its high-brilliance X-ray beams. In 2009, the prize was awarded to Venkatraman Ramakrishnan, Thomas A. Steitz, and Ada E. Yonath for studies on the structure and function of the ribosome; Ramakrishnan and Steitz utilized APS beamlines to obtain atomic-level resolution images essential for understanding protein synthesis. In 2012, Brian K. Kobilka and Robert J. Lefkowitz received the award for research on G protein-coupled receptors (GPCRs), with Kobilka employing APS X-rays to determine the first high-resolution structure of an activated GPCR, advancing drug design for this critical class of signaling proteins. Most recently, in 2024, David Baker, Demis Hassabis, and John M. Jumper were honored for computational protein design and structure prediction; Baker's team leveraged APS facilities to validate novel protein structures through X-ray crystallography, confirming designs that enable new therapeutic applications. Key discoveries at the APS span multiple decades and fields. In the 1990s, shortly after operations began in 1995, researchers achieved pioneering atomic-resolution protein structures, such as those of enzymes and viral proteins, which revolutionized by revealing precise molecular interactions previously unattainable with conventional sources. During the 2000s, APS studies uncovered nanoscale degradation mechanisms in lithium-ion batteries, identifying lithium formation and cracking that limit battery lifespan, informing improvements in for electric vehicles and renewables. In the , investigations into revealed phase transitions in superconductors and topological insulators, such as pressure-induced changes in iron-based compounds, providing insights into exotic states of matter for next-generation electronics. The APS's scientific impact is evidenced by its prolific output, with users generating over 2,000 peer-reviewed publications annually that cite facility contributions, spanning , , and research. These efforts have directly supported three Nobel Prizes and influenced broader advancements in physics and chemistry through structural and dynamical studies. In the 2020s, APS research has yielded highlights in and sciences, including operando analyses that enhanced efficiency by elucidating ion migration and defect formation, contributing to single-junction cell performance up to 26% conversion efficiency for scalable . Additionally, structural determinations of amyloid-beta fragments and oligomers have advanced understanding of pathology, revealing aggregation pathways that guide targeted therapies to disrupt plaque formation. APS-enabled discoveries have driven substantial economic value, particularly in pharmaceuticals, where X-ray structures facilitated development of blockbuster drugs like Kaletra (), an protease inhibitor approved in 2000 that generated billions in global sales and saved countless lives by halting AIDS progression. Similar contributions in semiconductors, through atomic-scale imaging of , have optimized designs and supported the multi-trillion-dollar .

Upgrade project

Project objectives

The APS Upgrade (APS-U) project was motivated by the limitations of the original , which, despite its advancements since commissioning in 1995, struggled to deliver sufficient and for emerging fields like nanoscience, ultrafast dynamics, and materials studies under extreme conditions. With global competitors such as the European Synchrotron Radiation Facility (ESRF) and SPring-8 pursuing major upgrades to low-emittance lattices, the project aimed to sustain U.S. leadership in hard science by leveraging the existing infrastructure to cost-effectively enhance capabilities for Department of Energy missions in energy, environment, biology, and . Key technical goals included achieving a 100- to 1000-fold increase in brightness for multi-keV photons and up to three orders of magnitude higher coherent , enabling diffraction-limited at nanoscale resolutions and time-resolved experiments with pulses. The project targeted a dramatic reduction in horizontal emittance from the original 3 nm·rad to ≤42 pm·rad at 200 mA operating current, alongside improvements in beam stability and single-bunch by factors of up to 25 times at select energies. These enhancements would support advanced techniques such as X-ray photon correlation spectroscopy (XPCS), , and high-energy , prioritizing conceptual breakthroughs over exhaustive metrics. To realize these goals, the design incorporated a 7-bend multi-bend achromat (MBA) to minimize emittance, featuring 35 insertion-device straight sections (with three dedicated to RF cavities) and replacing outdated components with advanced systems, including permanent magnets for quadrupoles and dipoles, and superconducting undulators for higher . Beamline development focused on nine new high-performance optimized for ultimate —such as long-distance setups for and —and upgrades to 15 existing ones, culminating in a total of 72 to maximize scientific throughput. The project's scope was funded by $815 million from the U.S. Department of Energy, spanning the to 2020s, with Critical Decision-3 (start of construction) approved in July 2019 following the final . This investment emphasized safety, efficiency, and integration with the existing complex while avoiding full reconstruction.

Implementation and timeline

The APS Upgrade (APS-U) project unfolded across distinct phases, commencing with from 2009 to 2014, during which the U.S. Department of Energy () approved the mission need in April 2010 and the Conceptual Design Report was finalized in 2011. This phase established the multi-bend achromat lattice as the core architectural innovation for enhancing beam brightness. Detailed engineering followed from 2015 to 2020, incorporating DOE Critical Decision 1 approval in May 2016 for design refinement and performance baseline, culminating in the Final Design Report in May 2019 and Critical Decision 3 approval in July 2019 to initiate procurement. Procurement and assembly spanned 2021 to 2023, focusing on fabricating over 1,300 magnets and integrating vacuum chambers into 200 pre-assembled modules offsite before tunnel delivery. Key milestones marked steady progress despite external pressures. The original storage ring shut down on April 17, 2023, initiating a one-year removal and installation period that minimized broader facility disruption by prioritizing components. New ring installation proceeded through 2024, with all modules aligned by March 2024; the first stored electron beam circulated on , 2024, validating initial functionality. Beamline commissioning began immediately thereafter in a phased approach, achieving Critical Decision 4 project closeout approval in September 2025 following verification of key performance parameters. The project faced significant challenges, including supply chain delays exacerbated by the COVID-19 pandemic, which affected component delivery and extended prototyping timelines. Magnet fabrication demanded sub-micron precision for the multi-bend achromat quadrupoles to maintain beam stability, while vacuum system integration required innovative thin-walled chambers compatible with the denser lattice—issues addressed through rigorous measurement protocols and vendor partnerships. These were resolved via collaborations with international vendors for specialized components like MBA magnets, ensuring compliance with exacting tolerances. Over 1,000 personnel contributed across staff, contractors, and external experts, with vendor contracts handling the bulk of MBA magnet production and module assembly to leverage specialized manufacturing capabilities. Transition strategies emphasized hybrid operations, allowing select beamlines to resume limited activities during installation to minimize scientific downtime; initial user experiments restarted in summer 2024, with full general user operations expanding by September 2024.

Post-upgrade performance

Following the successful completion of the APS Upgrade Project, the facility achieved key performance parameters surpassing some design goals, including a emittance of pm·rad (as of May 2025, surpassing the design of 42 pm·rad) and a vertical emittance of approximately 32 pm·rad at nominal operating currents. This low-emittance electron beam enables brightness on the order of 10^{21} photons/s/mm²/mrad²/0.1% bandwidth, representing a 500-fold improvement over the pre-upgrade configuration and supporting advanced coherent techniques. Beam stability has been maintained at levels of 4 μm vertically and 15 μm in brightness mode, ensuring reliable delivery for high-resolution experiments. Early operations commenced with the first user run in January 2025, marking the return to scientific activities after the shutdown. By October 2025, 51 of the 72 beamlines were accepting general users, with a total of 4,896 beam hours delivered during the , slightly below the target of 5,000 hours to accommodate additional commissioning needs. These initial runs have demonstrated robust multi-bunch operation at currents up to 200 mA, with swap-out injection maintaining beam quality throughout extended periods. Performance highlights from early experiments underscore the upgraded APS's enhanced capabilities, particularly in coherence for atomic-scale imaging applications such as and (XPCS). Initial results at feature beamlines like POLAR (4-ID) and CSSI (9-ID) have shown up to a 10-fold increase in rates compared to pre-upgrade baselines, enabling analysis of dynamic processes in materials and biological samples. Commissioning efforts encountered minor delays due to beam stability tuning and insertion device integration in early 2025, but these were resolved by August 2025 through refinements to the fast orbit feedback systems and bunch lengthening implementations. The APS Strategic Plan 2025-2029 further outlines optimizations, including superconducting undulator deployments and , to maximize throughput and coherence utilization across the facility. Looking ahead, the upgraded APS is projected to reach full operational capacity with all 72 beamlines by mid-2026, supporting for diverse scientific communities. As a leading fourth-generation light source, it holds potential for further enhancements, such as advanced timing modes and hybrid bunch schemes, while user numbers are expected to grow beyond 6,000 annually through initiatives like eBERlight for biological and environmental research.

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