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Ampulla

An ampulla is a small, globular flask typically crafted from glass or earthenware, featuring two handles and used in ancient Greco-Roman cultures to store ointments, perfumes, wine, or other liquids.^[1]^[2] These vessels, often produced in molds for mass replication, served both practical and ritual purposes, with archaeological examples recovered from sites across the Roman Empire, including pilgrim flasks containing holy water or oil as souvenirs from sacred sites.^[3] In Christian tradition, ampullae evolved into liturgical objects for holding consecrated oils employed in anointing ceremonies, such as coronations or sacraments, exemplified by ornate examples like the gold eagle-shaped Ampulla used in British royal inaugurations to dispense holy oil.^[4]^[5] Beyond its historical and religious applications, the term ampulla in anatomy refers to a sac-like enlargement or dilation at the terminus of a canal or duct, facilitating functions such as fluid storage or sensory detection.^[6] Notable instances include the ampullae of the semicircular canals in the inner ear, which house sensory hair cells for detecting angular head acceleration and contributing to balance, and the hepatopancreatic ampulla (ampulla of Vater), a reservoir where the common bile duct and main pancreatic duct converge before emptying into the duodenum to regulate digestive enzyme and bile release.^[1]^[7]^[8] These structures underscore the term's descriptive utility in biology, derived from the vessel's shape, with no significant controversies attached but ongoing research into associated pathologies like ampullary cancer highlighting their clinical relevance.^[9]

Etymology and General Definition

Linguistic Origins

The word ampulla derives from the Latin noun ampulla, which denoted a small, nearly globular flask or bottle, often with two handles, used in ancient Rome for containing oils, perfumes, wine, or other liquids.^[10] This Latin term is widely regarded as a diminutive form of amphora, a larger two-handled storage vessel, possibly arising from a Vulgar Latin phonetic contraction of amphora to amp(h)ora or amporela.^[10] ^[1] The progenitor amphora entered Latin from Ancient Greek amphoreús (ἀμφορεύς), a compound of amphi- ("on both sides") and phoreús ("bearer" or "carrier," from pherein, "to bear"), alluding to the jar's symmetrical handles designed for transport.^[11] ^[12] From Latin, ampulla passed into Old French as ampole (meaning "flask" or "vial") by the medieval period, entering Middle English around 1200 with a similar sense of a small container for liquids, particularly in ecclesiastical or medicinal contexts.^[10] The term's earliest attested use in English sources predates 1398, as recorded in medieval manuscripts.^[13] Over time, its linguistic application extended metaphorically to describe flask-like dilations in anatomical structures, preserving the original connotation of a swollen, bottle-shaped form, though this usage emerged later in scientific nomenclature rather than altering the word's core etymology.^[1]

Broad Conceptual Usage

The term ampulla broadly refers to a small, globular flask or bottle, usually with a narrow neck and often two handles, employed for containing liquids such as oils, perfumes, ointments, or wine. This conceptual form emphasizes a compact, sealed vessel suited for preservation and ritualistic or domestic transport, distinct from larger amphorae by its diminutive scale and ergonomic design for handling.^[1]^[14] In ecclesiastical contexts, the ampulla embodies a sacred container for consecrated substances, including chrism oil or Eucharistic wine and water, symbolizing purity and divine dispensation through its durable materials like glass or metal.^[14]^[2] The archetype's influence persists in modern pharmaceutical ampoules, which adopt the sealed, single-dose format for sterile liquids, prioritizing integrity against contamination.^[15] Anatomically, the concept analogically describes any localized dilation or sac-like widening in a duct or canal, evoking the vessel's bulbous profile to denote functional reservoirs for fluids or sensory mechanisms. This extension highlights causal shape-function parallels, where expansions facilitate storage, mixing, or mechanoreception without implying literal fabrication.^[2]^[14]

Historical and Archaeological Ampullae

Ancient Roman and Mediterranean Origins

The ampulla, derived from the Latin term denoting a small, bulbous flask with two handles, served in ancient Rome as a container for oils, perfumes, unguents, and occasionally wine or medicines. Roman authors such as Plautus, Horace, and Juvenal referenced ampullae in contexts of daily use, including by slaves carrying them for their masters' personal care. Pliny the Elder, in his Naturalis Historia (Book 19, chapter 19), describes their role in holding scented oils, underscoring their practical and cosmetic applications in Roman households. These vessels were metaphorically invoked in literature to signify inflated or pretentious speech due to their rounded, swollen form. Archaeological evidence from Roman sites reveals ampullae crafted primarily from glass or pottery, with glass variants emerging prominently during the late Republic and Imperial periods (circa 2nd century BCE to 4th century CE). Excavations in Italy, Gaul, and eastern provinces have yielded examples from domestic contexts, baths, and tombs, where they facilitated anointing rituals for the deceased. Ceramic ampullae, often simpler in design, appear in household assemblages, indicating mass production for everyday needs.^[16] In the broader Mediterranean context, ampulla forms trace roots to Hellenistic and pre-Roman traditions of small flasks for liquids, adapting earlier Greek and Eastern prototypes like the aryballos into the distinctive Roman biconical or globular shape with opposed handles for secure transport. Distribution across Roman territories, from Iberia to Asia Minor, reflects trade networks facilitating their use in personal hygiene, religious libations, and funerary practices, predating the specialized pilgrim variants of late antiquity.^[16]

Medieval Pilgrim and Religious Ampullae

Medieval pilgrim ampullae were small, portable flasks, typically crafted from lead alloy or pewter, designed to hold holy water, oil, or other sacred liquids collected from shrines during religious pilgrimages. These vessels emerged prominently in Western Europe during the late 12th century, coinciding with the expansion of saint cults and long-distance travel to sites like Canterbury and Walsingham, and remained popular until the early 14th century before declining in favor of badges and other souvenirs.^[17]^[18] Pilgrims acquired them as both mementos and practical aids for healing, often filling them at the saint's tomb and suspending them from cords via integral lugs for wear around the neck or attachment to clothing.^[19]^[20] Production centers operated near major shrines, with Canterbury exemplifying mass manufacturing starting shortly after Thomas Becket's martyrdom in 1170; tin or pewter ampullae were sold there from 1171 onward, featuring embossed imagery such as the saint's figure or shrine architecture to authenticate the pilgrimage.^[21] Similar artifacts linked to Our Lady of Walsingham in Norfolk, a key Marian pilgrimage destination, have been recovered in regions like North Devon, underscoring their distribution across England.^[22] Decorative motifs varied by site, including crucifixes, ascensions, or scallop shells evoking Santiago de Compostela, though the latter site favored shell badges over ampullae; these symbols reinforced the vessel's apotropaic function against illness or misfortune.^[23]^[24] Beyond personal devotion, ampullae facilitated communal rituals: their contents were applied to the afflicted for miraculous cures, poured onto agricultural fields to invoke bountiful harvests, or even buried in homes and barns for protection, reflecting a causal belief in the tangible efficacy of shrine-sourced fluids.^[19] Archaeological evidence, including thousands of discarded examples from urban sites like Southampton and London, indicates widespread loss during travel or deliberate opening for use, with many surviving intact due to their durable metal construction.^[18]^[25] By the 15th century, evolving pilgrimage practices and Reformation critiques diminished their prominence, though artifacts persist in museum collections, providing insight into medieval material piety without reliance on potentially biased ecclesiastical narratives.^[26]

Surviving Artifacts and Coronation Examples

Numerous lead-alloy ampullae used by medieval pilgrims have survived, primarily recovered from archaeological sites across England and preserved in museum collections worldwide. These artifacts, often depicting religious scenes such as the Crucifixion or saints like Thomas Becket, served to contain holy water or oil from shrines including Canterbury and Walsingham. For example, the British Museum houses a hollow-cast pilgrim souvenir from the shrine of St. Thomas Becket at Canterbury, shaped like a chasse and dating to the late medieval period.^[27] The Cleveland Museum of Art holds a similar ampulla featuring the Crucifixion on its front, linking to holy sites associated with Christ's life.^[28] Archaeological excavations have unearthed thousands of these flasks, illustrating the scale of pilgrimage in late medieval England.^[18] In coronation ceremonies, specialized ampullae have held consecrated anointing oils, with several historical examples enduring to the present. The Ampulla used in British coronations, a gold vessel crafted in the form of an eagle with outstretched wings, was commissioned for Charles II's coronation on April 23, 1661, and continues as part of the Crown Jewels at Westminster Abbey.^[29] It pours oil onto the 12th-century Anointing Spoon, the sole surviving medieval piece of English coronation regalia, for application during the rite.^[30] The Sainte Ampoule, a Roman glass vial approximately 1½ inches tall containing sacred chrism, anointed French monarchs from Clovis I in 496 until Charles X on May 29, 1825, at Reims Cathedral; legend attributes its oil to divine origin via a dove during Clovis's baptism, though it surfaced historically in 1131 for Louis VII's coronation.^[31]^[32] The relic, now housed in the Palais du Tau museum in Reims, was last employed in 1937 for an altar consecration.^[33] Scotland's coronation ampulla, a gold flask made around 1610, held oil for Charles I's anointing on June 18, 1633, at St. Giles' Cathedral in Edinburgh and represents one of the earliest extant pieces of Scottish royal goldsmithing, preserved at National Museums Scotland.^[34]

Anatomical Ampullae

Definition and Physiological Role

In anatomy, an ampulla is a dilated or sac-like enlargement of a canal, duct, tube, or other tubular channel, often flask-shaped or spherical in form, which contrasts with the narrower segments it connects. This expansion increases luminal capacity and may incorporate specialized muscular, mucosal, or neural elements to support localized functions.^[35]^[36]^[6] Physiologically, ampullae typically facilitate fluid dynamics, storage, or sensory processing by leveraging their expanded geometry for accumulation, mixing, propulsion, or mechanotransduction. Muscular walls in many ampullae enable peristaltic or sphincteric contractions to regulate flow and prevent reflux, as seen in ductal confluences where coordinated innervation maintains unidirectional transit of secretions.^[37]^[38] In sensory contexts, such as vestibular structures, the ampulla houses cristae ampullares—ridges lined with hair cells that detect angular acceleration through endolymph deflection, contributing to balance and spatial orientation via afferent signals to the brainstem.^[39] These roles underscore the ampulla's adaptive utility in optimizing pressure gradients, gamete or secretory delivery, and proprioceptive feedback across organ systems.^[40]

Ampullae in the Reproductive System

In the female reproductive system, the ampulla constitutes the widest and longest segment of the uterine tube, typically measuring approximately 5-8 cm in length and connecting the isthmus to the infundibulum.^[41] This region features a tortuous lumen lined by ciliated columnar epithelium with prominent mucosal folds that facilitate ovum transport through coordinated ciliary beating and muscular contractions.^[42] The ampulla serves as the primary site of fertilization, where spermatozoa encounter the ovum shortly after ovulation, enabling capacitation and acrosome reaction under the influence of tubal secretions rich in nutrients and enzymes.^[41] Post-fertilization, the zygote undergoes initial cleavage while being propelled toward the uterus via peristaltic waves and fluid currents generated in this dilated section.^[42] Pathologically, the ampulla's expansive structure predisposes it to ectopic pregnancies, accounting for the majority of tubal implantations due to impaired transport mechanisms or adhesions from conditions like pelvic inflammatory disease.^[41] Surgical interventions such as salpingostomy target this region to preserve fertility when ectopic gestation occurs.^[41] Histologically, the ampulla's wall comprises an inner mucosal layer with secretory cells, a thick smooth muscle layer for propulsion, and an outer serosal covering, adaptations that support its role in gamete interaction and early embryonic protection.^[43] In the male reproductive system, the ampulla of the ductus deferens represents the dilated, tortuous terminal portion of the vas deferens, located near the fundus of the urinary bladder where it expands to form a reservoir.^[44] This fusiform enlargement, approximately 5 cm long, stores mature spermatozoa and seminal fluid components prior to ejaculation, with its muscular wall contracting to propel contents into the ejaculatory duct upon sympathetic stimulation.^[45] The ampulla's epithelium includes pseudostratified columnar cells forming glandular invaginations that secrete fructose, prostaglandins, and ergothioneine, enhancing sperm motility and viability within semen.^[46] It merges with the seminal vesicle duct to form the ejaculatory duct, which penetrates the prostate to deliver spermatozoa into the urethra.^[47] Obstruction or inflammation in this region, often secondary to vasectomy or infection, can impair fertility by blocking sperm transit.^[48]

Ampullae in the Vestibular System

The ampullae in the vestibular system are dilated regions at one end of each of the three semicircular ducts, which form part of the membranous labyrinth in the inner ear. These structures, one per duct (anterior, posterior, and lateral), connect to the utricle and house specialized sensory epithelium for detecting rotational movements of the head.^[49]^[50] The semicircular ducts, filled with endolymph fluid, are oriented in mutually perpendicular planes to provide three-dimensional angular sensitivity.^[51] Within each ampulla lies the crista ampullaris, a saddle-shaped ridge of epithelial tissue protruding into the lumen and covered by a gelatinous dome called the cupula. The crista contains type I and type II hair cells, mechanoreceptors with stereocilia and a single kinocilium projecting into the cupula; deflection of these processes modulates neurotransmitter release to afferent neurons of the vestibular nerve (cranial nerve VIII).^[52]^[50] The cupula, anchored to the ampullary wall, spans the duct's cross-section and moves passively with endolymph flow, exhibiting viscoelastic properties that allow rapid response to acceleration (threshold around 0.1–1°/s²) and quick recovery.^[51]^[49] Functionally, the ampullae transduce angular acceleration and deceleration via inertial lag of endolymph during head rotation. For instance, ampullopetal flow (toward the ampulla) in an excited canal depolarizes hair cells by bending stereocilia toward the kinocilium, increasing firing rates in ipsilateral vestibular ganglion afferents; the opposite occurs in the coplanar inhibitory canal.^[51]^[52] This push-pull mechanism enables precise detection of yaw, pitch, and roll, contributing to the vestibulo-ocular reflex for gaze stabilization and vestibulospinal reflexes for posture.^[53] Disruptions, such as cupular detachment in benign paroxysmal positional vertigo, impair this detection, leading to vertigo from erroneous signals.^[49] The system operates without adaptation during constant velocity but signals primarily during dynamic changes, aligning with inertial physics of fluid dynamics in confined tubes.^[51]

Hepatopancreatic Ampulla (Ampulla of Vater)

The hepatopancreatic ampulla, commonly known as the ampulla of Vater, is a dilated junction formed by the confluence of the common bile duct and the main pancreatic duct, serving as a conduit for the release of bile and pancreatic secretions into the duodenum.^[40] Located within the major duodenal papilla on the medial wall of the descending (second) portion of the duodenum, approximately 8-10 cm distal to the pylorus, it protrudes slightly into the intestinal lumen and is surrounded by the head of the pancreas.^[54] ^[55] Functionally, the ampulla acts as a reservoir that temporarily stores and coordinates the discharge of bile from the liver and gallbladder—essential for fat emulsification and absorption—and pancreatic enzymes critical for protein, carbohydrate, and lipid digestion.^[7] Its outflow is regulated by the sphincter of Oddi, a muscular complex comprising the sphincter ampullae, pancreatic sphincter, and biliary sphincter, which maintains pressure gradients to facilitate unidirectional flow into the duodenum while preventing reflux of intestinal contents into the biliary or pancreatic systems.^[56] This mechanism is hormonally modulated, with cholecystokinin promoting relaxation and secretin enhancing secretion, ensuring synchronized delivery during meals.^[55] In approximately 10% of individuals, anatomical variants such as pancreas divisum occur, where the dorsal and ventral pancreatic ducts fail to fuse embryonically, potentially altering ampullary drainage and predisposing to pancreatitis.^[40] Clinically, the ampulla is significant as a site of pathology; obstruction by gallstones, parasites, or tumors can lead to biliary stasis, jaundice, cholangitis, or acute pancreatitis due to upstream pressure buildup.^[57] Ampullary adenocarcinoma, arising from glandular epithelium, accounts for about 0.5-1% of gastrointestinal malignancies but carries a relatively better prognosis than pancreatic cancer when detected early, with 5-year survival rates up to 40-50% post-resection.^[58] Endoscopic procedures like ERCP exploit its accessibility for biopsy, stent placement, or sphincterotomy to relieve obstructions.^[7]

Other Anatomical Instances

The rectal ampulla refers to the dilated middle and lower portions of the rectum, forming an expanded reservoir approximately 12-15 cm in length from the rectosigmoid junction to the anorectal ring, which facilitates temporary storage of fecal matter prior to defecation.^[59] This dilatation arises as the rectum transitions from the narrower sigmoid colon, achieving a greater transverse diameter of up to 4-5 cm to accommodate contents without immediate expulsion, aided by the relaxation of surrounding pelvic floor musculature.^[60] The ampulla's mucosal lining features three permanent transverse folds, known as the valves of Houston, which support continence by preventing premature leakage while allowing passage during defecation.^[59] In clinical contexts, the rectal ampulla's capacity and distensibility are critical for evaluating conditions such as fecal incontinence or constipation; for instance, digital rectal examination can assess its tone and contents, with normal resting volume estimated at 150-300 mL before the urge to defecate arises.^[61] Pathologies like rectal prolapse or tumors can distort this structure, impairing its reservoir function and leading to symptoms such as tenesmus or obstructed defecation.^[60] Unlike the more flask-like ampullae in ductal systems, the rectal ampulla's role emphasizes storage and controlled release, integrated with the internal anal sphincter's involuntary control and the external sphincter's voluntary regulation.^[59]

Ampullae in Zoology and Botany

In Echinoderms and Other Invertebrates

In echinoderms, ampullae form paired muscular bulbs attached to the proximal end of each tube foot within the water vascular system, serving as hydraulic reservoirs that regulate fluid pressure for locomotion and manipulation.^[62] Contraction of the ampulla's thin muscular walls forces seawater through a lateral canal into the extensible tube foot, extending it outward, while relaxation permits retraction through elastic recoil of the foot's walls or supplementary muscle contraction.^[63] This mechanism, powered by the madreporite's intake of seawater into the ring canal and subsequent distribution via five radial canals, enables coordinated arrays of thousands of tube feet per arm in species like starfish (Asterias spp.) to achieve slow crawling speeds of up to 15 cm per minute on substrates.^[64] Ampullae project into the coelom above ambulacral pores between ossicles, with their size scaling to tube foot demands—larger in active predators like sea stars than in sessile forms.^[65] The water vascular system's ampullae-tube foot units also support secondary functions, including prey capture via adhesive podia in ophiuroids and echinoids, gas exchange across permeable foot epithelia, and sensory roles through nerve endings detecting mechanical stimuli.^[66] In holothuroids (sea cucumbers), modified ampullae contribute to evisceration defenses by rapidly expelling coelomic fluids, while fossil evidence from Paleozoic echinoderms indicates conserved ampullary protraction dominance in early clades like Echinozoa.^[67] Among other invertebrates, ampullae appear in colonial tunicates such as botryllid ascidians, where they denote extensible, blood-filled vascular projections from the tunic's inner surface that facilitate histocompatibility assessments during inter-colony encounters.30337-9) Upon contact between compatible genotypes, ampullary tips promote tunic dissolution and vascular anastomosis, enabling parabiosis and shared resource circulation; incompatible pairings trigger cytotoxic rejection via ampullary-mediated signaling.30337-9) These structures, absent in solitary ascidians, evolved convergently to support modular colonial growth, with ampullary fusion documented experimentally in species like Botryllus schlosseri under controlled grafting assays since the 1980s.30337-9)

Botanical Analogues

In the genus Utricularia (bladderworts), flask-shaped suction traps on submerged leaves function as carnivorous organs, historically termed ampullae for their vesicular morphology resembling ancient Roman flasks. These structures, typically 0.2 to 8 mm in diameter depending on species, feature a thin-walled bladder with a sealed entrance door that creates negative pressure; upon prey contact, the door opens, flooding the interior with water in milliseconds to capture small aquatic organisms like protozoans and microcrustaceans. The ampullae reset via active ion pumping to restore the vacuum, enabling repeated trapping with efficiencies up to 90% for suitable prey sizes in species such as U. vulgaris.^[68] The specific epithet of Nepenthes ampullaria, a tropical pitcher plant, reflects the flask-like form of its ground-hugging pitchers, which measure 7-12 cm tall and function as pitfall traps filled with digestive fluid to drown and break down insects and small vertebrates. Unlike the rapid suction of Utricularia ampullae, these structures rely on passive gravitational capture, with waxy inner surfaces and downward-pointing peristomes preventing escape; nutrient-poor habitats drive this adaptation, as evidenced by field studies showing pitchers capturing up to 50 prey items monthly. The flask shape maximizes fluid retention while minimizing evaporation in humid environments. Broader botanical usage of ampulla denotes any dilated, flask-like reservoir, such as nectar-secreting glands in certain orchids or dilated lactifers in euphorbiaceous plants storing latex, though these lack the specialized trapping mechanisms of carnivorous examples. Such structures parallel anatomical ampullae in serving storage or secretory roles, with causal links to environmental pressures like nutrient scarcity favoring their evolution in over 250 Utricularia species across freshwater ecosystems worldwide.^[14]

References

[1]
AMPULLA Definition & Meaning - Merriam-Webster
1. a glass or earthenware flask with a globular body and two handles used especially by the ancient Romans to hold ointment, perfume, or wine
[2]
AMPULLA definition in American English - Collins Dictionary
1. a nearly round bottle with two handles, used by the ancient Greeks and Romans 2. Anatomy a sac or dilated part of a tube or canal, as of a milk duct in a ...
[3]
ampulla | British Museum
The mouth of the vessel is intact and flare. It has two handles. Two-piece mould. Micaceous brown Nile silt, with a worn matt red slip: probably a misfired ...
[4]
Ampulla - The Episcopal Church
A vessel or container for consecrated oils. Ampullae of clay or glass were found in the tomb walls of ancient Christian catacombs.
[5]
Tell me about... the Ampulla and Anointing Spoon
Apr 26, 2023 · The Ampulla is a small, gold vessel in the shape of an eagle with outstretched wings. It is used to hold the holy oil which anoints the Monarch during the ...<|control11|><|separator|>
[6]
Medical Definition of Ampulla - RxList
Ampulla: In anatomy, a sac-like enlargement of a canal or duct. The ampulla of Vater is the enlargement of the ducts from the liver and pancreas at the point ...
[7]
Ampulla of Vater: What It Is, Location & Function - Cleveland Clinic
The ampulla is a reservoir that holds bile and pancreatic enzymes and releases them into your intestine to help digest food.
[8]
Ampulla of Vater - Mayo Clinic
The ampulla of Vater is located where the bile duct and pancreatic duct join and empty into the small intestine.<|separator|>
[9]
Hepatopancreatic ampulla: Anatomy and location - Kenhub
Apr 22, 2024 · The hepatopancreatic ampulla is a small reservoir at the confluence of the bile and pancreatic ducts, located in the descending duodenum, ...
[10]
Ampulla - Etymology, Origin & Meaning
1200, from Old French ampole "flask, vial," from Latin ampulla "small globular flask or bottle," which is of uncertain origin, perhaps a contracted form of ...
[11]
Amphora - Etymology, Origin & Meaning
Early 14c. "amphora" means a two-handled vessel for wine or oil, originating from Greek amphoreus, from amphi "both sides" + phoreus "bearer," via Latin.
[12]
amphora - Wiktionary, the free dictionary
From Latin amphora (“large wine vessel, Roman unit of liquid measure”), from Ancient Greek ἀμφορεύς (amphoreús, “two-handled pitcher, Greek units of liquid ...
[13]
ampulla, n. meanings, etymology and more - Oxford English Dictionary
The earliest known use of the noun ampulla is in the Middle English period (1150—1500). OED's earliest evidence for ampulla is from before 1398, ...
[14]
AMPULLA Definition & Meaning - Dictionary.com
plural · a vessel for the wine and water used at the altar. · a vessel for holding consecrated oil. a two-handled bottle having a somewhat globular shape ...
[15]
Ampul - Etymology, Origin & Meaning
Ampoule, from Latin ampulla via French, means a sealed container holding medicine doses, originating as a flask or vial.
[16]
Flask - Legio X Fretensis
The Latin name for a flask that has come down to us is ampulla. In antiquity, ceramic flasks were widespread, but metal versions of these vessels have also been ...
[17]
Record ID: SF-770309 - MEDIEVAL ampulla
Spencer (1998, 3) suggests that ampulla were popular in England from the second half of the 12th century until the early 14th century, when they were largely ...
[18]
Ampullae and Badges: Pilgrim Paraphernalia in Late Medieval ...
Apr 30, 2018 · Introduction: From Cuckoo Lane (Southampton) to London's Watlynge Strete to Canterbury, pilgrims in late medieval England carried on their ...
[19]
Medieval Pilgrims' Ampullae - The Ickeny Collection
Ampullae were a way of bringing direct healing to those sick at home or libations to the fields. Many of those found today are broken, opened in antiquity for ...Missing: history | Show results with:history
[20]
[PDF] Pilgrims in Medieval Lincolnshire - Lincoln Museum
These ampullae were worn on a pilgrim's hat or around his neck as proof of his pilgrimage, and the holy water which they contained was treated as a curative for ...
[21]
Explore our Becket and Chaucer Case Contents
Ampullae of tin or tin/lead alloy (pewter) were being made and sold in Canterbury as early as 1171, a year after Becket's death.Missing: artifacts | Show results with:artifacts
[22]
North Devon in 100 Objects: 95. A Pilgrim's Ampulla
Found at Pilton, these ampullae came originally from the shrine of Our Lady of Walsingham in Norfolk, one of the greatest shrines in medieval Christendom.
[23]
Pilgrim's Ampulla with the Ascension (back) | Cleveland Museum of Art
Cast into the sides of this ampulla are scenes of Christ's Crucifixion on the front and the Ascension on the back. The use of such sacred images on these ...<|separator|>
[24]
Medieval pilgrim shell tokens & St James' Way | London Museum
Apr 24, 2024 · 15 medieval tokens – including badges, pendants and ampulla (tiny containers) – can be linked to the Spanish pilgrimage site Santiago de Compostela.
[25]
Ampulla - Medieval London - Fordham University
During the twelfth through fourteenth centuries, pilgrims were likely to purchase an ampulla, a type of container filled with holy water or oil.Missing: history | Show results with:history
[26]
Portable blessings - medieval pilgrims' ampullae - TimesAncient
Dec 4, 2021 · Here we take a look at late-medieval ampullae, one of a variety of types of pilgrim souvenirs bought and sold as part of the medieval cult of saints.
[27]
pilgrim badge; souvenir; ampulla - British Museum
Description: A lead alloy, hollow-cast pilgrim souvenir from the shrine of St Thomas Becket at Canterbury. It is in the form of a chasse-shaped ampulla, ...
[28]
Pilgrim's Ampulla with the Crucifixion (front) - Cleveland Museum of Art
The images found on the sides of surviving lead pilgrims' ampullae include scenes relating to the life of Christ, and by extension to the holy sites (loca ...
[29]
Ampulla and spoon - Westminster Abbey
The ampulla, shaped like an eagle, holds the consecrated oil with which the monarch is anointed. It was made for the coronation of King Charles II in 1661.Missing: examples | Show results with:examples
[30]
The Crown Jewels: Coronation Regalia - Royal Collection Trust
The oldest item in the Coronation Regalia is the 12th-century Coronation Spoon. It is the only piece of royal goldsmiths' work to survive from that century.
[31]
The Holy Ampulla: Divine Oil From Heaven That Anointed French ...
Jun 4, 2024 · The Holy Ampulla, also known as the Sainte Ampoule, was used in the coronation of French kings for nearly a millennium.Missing: history | Show results with:history
[32]
Holy Ampulla | Religion Wiki - Fandom
The ampoule, a vial of Roman glass about 1½ inches tall, came to light at Reims in time for the coronation of Louis VII in 1131. The legend that was associated ...
[33]
The reliquary of the Holy Ampoule | Palais du Tau in Reims
The Balm of the Holy Ampoule has only been used once since the coronation of Charles X, in 1937, at the consecration of the altar in Reims Cathedral ...Missing: history | Show results with:history
[34]
Anointed with oil: The coronation ampulla of Charles I
This object is one of the earliest surviving pieces of Scottish-made gold. It was used at the Scottish coronation of Charles I, which was held in Edinburgh.Missing: examples | Show results with:examples
[35]
Benign anatomical mistakes: "ampulla of Vater" and "papilla of Vater"
The term "ampulla" refers to a dilated part of a duct or other channel. Thus, this word is topographically correct to describe the dilatation at the confluence ...
[36]
Definition of ampulla - NCI Dictionary of Cancer Terms
Listen to pronunciation. (am-PUH-luh) A sac-like enlargement of a canal or duct.
[37]
Papilla of Vater: structure and function - PubMed
The papilla of Vater regulates bile flow into the duodenum and prevents reflux into bile and pancreatic ducts, using a special muscular, neural and mucosal ...
[38]
Functional anatomy of the papilla Vateri: biomechanical ... - PubMed
The ampulla Vateri has finger-like mucosal folds forming pocket-like valves that allow unidirectional flow and may explain endoscopic difficulties.<|separator|>
[39]
Ampulla of Vater: Comprehensive Anatomy, MR Imaging ... - PubMed
The ampulla of Vater is a complex structure where MR can detect lesions, and ERCP is used for diagnosis, but may not be entirely reliable.
[40]
Ampulla of Vater. Anatomic, embryologic, and surgical aspects
The ampulla of Vater corresponds to the dilated junction of the common bile duct and main pancreatic duct, if present.
[41]
Anatomy, Abdomen and Pelvis: Fallopian Tube - StatPearls - NCBI
Jul 24, 2023 · The ampulla is the most common site of ectopic pregnancies, which are either treated medically or removed surgically with a salpingostomy ( ...Anatomy, Abdomen And Pelvis... · Blood Supply And Lymphatics · Clinical Significance
[42]
The Fallopian Tubes (Uterine) - Structure - TeachMeAnatomy
Oct 9, 2024 · Ampulla – widest section of the uterine tubes. Fertilization usually occurs here. Isthmus – narrow section of the uterine tubes connecting the ...Anatomical Structure · Vascular Supply And... · Innervation
[43]
Oviduct - Female reproductive system: The Histology Guide
This leads into a longer, thin walled ampulla, which has primary, secondary and tertiary longitudinal mucosal folds. This leads into a short thicker-walled ...
[44]
Ampulla of ductus deferens - e-Anatomy - IMAIOS
At the fundus of the bladder, the ductus deferens becomes enlarged and tortuous, and this portion is termed the ampulla. A small triangular area of the fundus ...
[45]
Vas Deferens - an overview | ScienceDirect Topics
It includes an ampulla, which serves as a reservoir for sperm. How useful is this definition?
[46]
The ampulla of the ductus deferens in man - NIH
The epithelial lining formed multiple branched invaginations in the lamina propria and submucosa giving rise to glandular structures.
[47]
Ampulla of Ductus Deferens | Complete Anatomy - Elsevier
The ampulla of the ductus deferens joins the duct of the seminal vesicle to form the ejaculatory duct, which enters the prostatic urethra.
[48]
Ductus Deferens (Vas Deferens) and Ejaculatory Duct Anatomy
Mar 27, 2025 · The ductus deferens, or vas deferens, is a fibromuscular tube that is a continuation of the epididymis and is an excretory duct of the testis.
[49]
Vestibular System Anatomy: Overview, Membranous Labyrinth ...
Apr 9, 2025 · One end of each canal is dilated to form the ampulla, which contains a saddle-shaped ridge termed the crista ampullaris; the sensory epithelium ...
[50]
The Semicircular Canals - Neuroscience - NCBI Bookshelf - NIH
Each of the three semicircular canals has at its base a bulbous expansion called the ampulla (Figure 14.7), which houses the sensory epithelium, or crista, that ...
[51]
Chapter 10: Vestibular System: Structure and Function
Each slender duct has one ampulla. When the head turns, fluid in one or more semicircular ducts pushes against the cupula and bends the cilia of the hair cells.
[52]
Vestibular system: Anatomy, pathway and function | Kenhub
The terminal part of each canal ends with a dilation called the ampulla, which opens into the vestibule. The ampulla of each semicircular canal contains a ...
[53]
Vestibular System: Function & Anatomy - Cleveland Clinic
Jun 19, 2024 · Each canal ends in a structure called an ampulla. The ampulla contains hair cells that extend into a gelatin-like substance called cupula.
[54]
Anatomy & Physiology - Gallbladder & Bile Duct Cancer
Around the ampulla of Vater. The peri-ampullary region is comprised of 4 structures; the ampulla, the duodenum, the bile duct and the head of the pancreas.
[55]
Hepatopancreatic ampulla - e-Anatomy - IMAIOS
The hepatopancreatic ampulla (ampulla of Vater) is a small spherical reservoir formed by the union of the pancreatic duct and the common bile duct.
[56]
Anatomy, Abdomen and Pelvis, Sphincter of Oddi (Hepatopancreatic ...
Jul 4, 2023 · Clinical Significance · Nausea and vomiting, which may be mistaken for a gallbladder attack · Transient increase in liver function tests (LFT) or ...
[57]
Anatomy, Abdomen and Pelvis: Biliary Ducts - StatPearls - NCBI - NIH
Clinical Significance The biliary tract provides an outlet to transport bile into the gastrointestinal tract, which facilitates the absorption of fat-soluble ...
[58]
Ampullary cancer - Symptoms and causes - Mayo Clinic
Dec 5, 2023 · Ampullary cancer happens when cells in the ampulla of Vater develop changes in their DNA. A cell's DNA holds the instructions that tell a cell ...Overview · Symptoms · CausesMissing: significance | Show results with:significance
[59]
Anatomy, Abdomen and Pelvis: Large Intestine - StatPearls - NCBI
Apr 6, 2025 · The middle segment of the rectum, known as the ampulla, serves as an expanded reservoir for fecal storage. The rectum has distinct anterior ...
[60]
Large Intestine Anatomy - Medscape Reference
Mar 6, 2025 · The rectum has a dilated middle part called the ampulla, which contains three semilunar transverse mucosal folds called "valves of Houston.<|separator|>
[61]
Rectal Ampulla - an overview | ScienceDirect Topics
Rectal ampulla is defined as a part of the rectum that can be assessed during imaging modalities such as MR defecography to evaluate pelvic floor descent. AI ...
[62]
Echinoderm Structure and Function - Advanced | CK-12 Foundation
They are basically thin-walled cylinders with muscular bulb-shaped structures called ampullae on the internal end and suckered structures called podia on the ...
[63]
9.3: Reading- Echinoderms - Biology LibreTexts
Mar 24, 2024 · Each tube foot has a fleshy bulb or ampulla attached so that the entire structure looks like an medicine dropper or pipette. ... Claw-like ...
[64]
Phylum Echinodermata | Biology for Majors II - Lumen Learning
The ring canal connects the radial canals (there are five in a pentaradial animal), and the radial canals move water into the ampullae, which have tube feet ...Characteristics Of... · Morphology And Anatomy · Water Vascular System
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[PDF] Water Vascular System of Starfish - BP Chaliha College
The ampulla lies within the arm, projecting into the coelom above the ambulacral pore which is a gap between the adjacent ambulacral ossicles for the passage of ...
[66]
Phylum Echinodermata | manoa.hawaii.edu/ExploringOurFluidEarth
This five-sided radial structure of echinoderms makes the body strong (Fig. 3.86). A five-sided skeleton is stronger than a four- or six-sided one because ...
[67]
[PDF] FOSSIL ECHINODERMS - The Palaeontological Association
In the Echinozoa, either the accessory ampullae assume the dominant role in tube-foot protractions or, as in aspidochirote holothuroids, protraction is ...<|separator|>
[68]
A Historical Perspective of Bladderworts (Utricularia): Traps ... - NIH
Dec 3, 2021 · The traps, historically known as utriculae (utricules), urceoli, ampullae, or bladders, are foliar structures shaped as small vesicles ...