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Cysticercus

Cysticercus is the larval stage of certain tapeworms in the genus Taenia, particularly Taenia solium (the pork tapeworm), manifesting as a fluid-filled, bladder-like cyst containing an invaginated scolex, typically measuring 5–15 mm in length, that develops in the tissues of intermediate hosts such as pigs and humans.^[1] This stage is a key component of the parasite's complex life cycle, where eggs excreted in the feces of infected definitive hosts (usually humans) are ingested by intermediate hosts, hatching into oncospheres that penetrate the intestinal wall, migrate via the bloodstream, and encyst in organs like muscles, brain, or eyes over 60–70 days.^[1]^[2] In humans, accidental ingestion of T. solium eggs—often through contaminated food, water, or poor hygiene—leads to cysticercosis, a parasitic infection where these cysts can lodge in subcutaneous tissues, muscles, or the central nervous system, potentially causing severe complications. It is estimated to affect 2.56–8.30 million people worldwide (WHO, 2022).^[3] Neurocysticercosis, the most dangerous form, occurs when cysticerci invade the brain, resulting in inflammation, seizures, epilepsy, headaches, or even death due to mass effect or hydrocephalus.^[1]^[2] Taenia solium is the primary species causing human cysticercosis; while Taenia saginata (beef tapeworm) produces cysticerci in cattle, it does not typically cause disease in humans. The disease is a neglected tropical infection endemic in regions of Latin America, sub-Saharan Africa, and Asia where sanitation is inadequate and pigs roam freely.^[3]^[2] Transmission of cysticercosis is fecal-oral and distinct from taeniasis, which results from consuming undercooked pork harboring cysticerci that mature into adult tapeworms in the human intestine; prevention relies on improved hygiene, meat inspection, pig vaccination, and treatment of human carriers.^[1]^[3] Globally, cysticercosis contributes to up to 30% of epilepsy cases in endemic areas, underscoring its public health impact despite being preventable through integrated "One Health" strategies involving veterinary and human medicine.^[3]^[2]

Taxonomy and Classification

Definition

The cysticercus is the encysted larval stage, often referred to as the bladder worm, of cestodes belonging to the family Taeniidae, most notably Taenia solium (the pork tapeworm) and Taenia saginata (the beef tapeworm).^[4]^[5] This stage develops in intermediate hosts such as pigs or cattle, forming a fluid-filled cyst that serves as the infective form for the definitive host, humans.^[1] Unlike earlier larval forms such as the oncosphere—the hexacanth embryo released from eggs—or the broader category of metacestodes, the cysticercus is characterized by its distinctive encysted structure: a single, spherical or oval vesicle containing an inverted scolex (the future head of the adult tapeworm) suspended in a clear, gelatinous fluid.^[2]^[6] This inversion allows the scolex to remain protected until activation, distinguishing it from non-encysted or multi-scolex larval variants in other cestodes.^[7] Key features of the cysticercus include its typical size of 5-15 mm in diameter for T. solium, though it can grow larger in some cases, with a single larva per cyst.^[1] Upon ingestion by the definitive host, the scolex evaginates—uncoiling and everting from the vesicle—to attach to the intestinal wall and initiate development into the adult tapeworm.^[8] This stage plays a critical role in the transmission of taeniid tapeworms within their complex life cycles.^[3]

Etymology and Naming

The term cysticercus derives from the Ancient Greek words kystis (κύστις), meaning "bladder" or "cyst," and kerkos (κέρκος), meaning "tail," alluding to the bladder's fluid-filled sac and the protruding, tail-like scolex of the larval form.^[7] This nomenclature was coined by the German naturalist Johann Zeder in his 1800 textbook on helminthology, Naturgeschichte der Eingeweidewürmer, to classify the larval stages of taeniid cestodes as a distinct genus, recognizing their parasitic bladder-worm morphology distinct from adult tapeworms.^[9] Historical accounts of these larvae predate the formal term, with early observations emerging in the Renaissance period; Italian physician and naturalist Francesco Redi provided one of the earliest detailed descriptions in his 1684 treatise Osservazioni Intorno Agli Animali Viventi che si Trovano Negli Animali Viventi, where he examined and illustrated cysticercus-like structures, such as Cysticercus pisiformis in the mesentery of hares, establishing their animal origin and refuting spontaneous generation.^[10] By the late 18th century, as understanding of helminth life cycles advanced, Johann Christian Friedrich Gmelin introduced the species name Taenia cellulosae in 1790 for the vesicular larvae found in pigs, initially treating them as separate entities from adult taeniids.^[9] Zeder's genus Cysticercus encompassed these forms, but 19th-century pathologists like Karl Theodor von Siebold later linked them definitively to adult Taenia species through experimental infections, leading to their integration into cestode taxonomy under the class Cestoda and family Taeniidae by the mid-1800s.^[9] In contemporary taxonomic conventions, cysticercus serves as a generic descriptor for the metacestode stage, with binomial nomenclature applied to specific larval forms following Linnaean principles; for instance, Cysticercus cellulosae denotes the larva of Taenia solium, while Cysticercus bovis refers to the larva of Taenia saginata.^[7] These names often function as synonyms or junior designations for the corresponding adult tapeworm species' immature stages, reflecting their shared phylogenetic placement within Taeniidae, though the genus Cysticercus itself is now considered a junior synonym in some classifications to emphasize the unified life cycle.^[9]

Life Cycle

Host Involvement

Cysticercus, the larval stage of tapeworms in the genus Taenia, relies on specific host relationships for its life cycle completion, with distinct roles for definitive and intermediate hosts that facilitate transmission through ecological interactions such as foraging behaviors and environmental contamination. For Taenia solium, the pork tapeworm, humans serve as the primary definitive host, harboring the adult tapeworm in the intestine after consuming undercooked pork containing cysticerci.^[1] Pigs act as the main intermediate host, where cysticerci develop in muscle and other tissues following ingestion of eggs shed in human feces, often through access to contaminated soil or water in endemic areas.^[3] Humans can also function as accidental intermediate hosts for T. solium, leading to cysticercosis when eggs are ingested via the fecal-oral route, typically due to poor sanitation and close human-animal proximity in rural settings.^[1] In contrast, for Taenia saginata, the beef tapeworm, humans are the exclusive definitive host, with the adult worm residing in the human intestine after ingestion of infected beef.^[11] Cattle function as the primary intermediate host, developing cysticerci in their muscle tissues upon consuming eggs from human feces, which are dispersed in pastures through open defecation or wastewater irrigation, highlighting the role of agricultural practices in sustaining transmission.^[12] While pigs rarely serve as intermediate hosts for T. saginata, and human cysticercosis from this species is exceptionally uncommon, the ecological dependence on cattle underscores how livestock grazing patterns influence parasite dissemination in bovine populations.^[13] Transmission dynamics of cysticercus emphasize the ingestion of embryonated eggs by intermediate hosts, which hatch in the gut and migrate to tissues to form cysticerci, perpetuating the cycle when infected animal tissues are consumed by definitive hosts.^[3] These interactions are ecologically driven by behaviors such as scavenging in pigs or grazing in cattle, which expose them to fecal-contaminated environments, while human habits like improper waste disposal amplify the risk, particularly in regions with integrated human-livestock systems.^[12] For T. solium, the dual role of humans as both definitive and accidental intermediate hosts creates a unique zoonotic loop, intensified by socioeconomic factors that promote egg dissemination.^[1]

Developmental Stages

The developmental stages of Cysticercus, the larval form of tapeworms such as Taenia solium, begin when eggs containing oncospheres are ingested by an intermediate host, such as pigs or humans.^[1] In the host's small intestine, digestive enzymes and bile salts trigger the hatching of the oncosphere from the egg, activating its penetration apparatus.^[14] The motile oncosphere then burrows through the intestinal villi, entering the bloodstream or lymphatic system to migrate to preferred tissues like muscle, brain, or eyes.^[15] Over the subsequent 60 to 70 days, the post-oncospheral form undergoes physiological transformations, growing into a mature cysticercus—a fluid-filled bladder with an invaginated scolex.^[16] This development involves rapid cellular proliferation and differentiation, forming the characteristic vesicular structure that allows the larva to remain dormant in host tissues.^[6] In T. solium, this process typically completes within 2 to 3 months, enabling the cysticercus to become infective for the definitive host.^[17] Upon ingestion by the definitive host (humans for T. solium), the cysticercus responds to gastric acid and intestinal enzymes by initiating evagination, where the scolex inverts out of the bladder wall.^[18] This extrusion, driven by muscular contractions and osmotic pressure changes, allows the scolex to attach to the intestinal mucosa using its hooks and suckers, marking the transition to the adult tapeworm stage.^[8] Cysticerci can remain viable in intermediate hosts for several years, evading immune detection through molecular mimicry and encapsulation.^[3] If not ingested, they eventually degenerate, undergoing involution where the bladder collapses, the scolex atrophies, and the cyst calcifies, often provoking localized inflammatory responses from the host immune system.^[2] This degeneration process can span months to years, depending on host factors and cyst location.^[19]

Morphology

External Structure

The cysticercus, the metacestode larval stage of Taenia tapeworms, exhibits a distinctive external form consisting of a fluid-filled, oval-shaped bladder housing an invaginated scolex at one pole. This bladder is enclosed by a thin, acellular tegument that appears translucent to opaque white, providing a smooth surface devoid of external hooks, spines, or other protrusions, as the scolex remains retracted within the cyst until evagination in the definitive host.^[7] The fluid within the bladder contributes to the cyst's buoyancy and protection of the scolex during encystment in intermediate host tissues.^[1] In Taenia solium, the cysticercus (Cysticercus cellulosae) typically measures 5–15 mm in length, though viable cysts can extend up to 5 cm in expansive sites such as the central nervous system.^[1] Its oval bladder is often semi-translucent initially, becoming more opaque as it matures, and is commonly embedded in muscle, subcutaneous tissue, or organs without a prominent external stalk.^[20] For Taenia saginata, the cysticercus (Cysticercus bovis) presents as a smaller, whitish-yellow, oval nodule, generally 6–10 mm long and 4–6 mm wide, with a bulging, fluid-filled appearance when viable and protruding from host muscle surfaces.^[21] The thin-walled tegument is smooth and unadorned externally, reflecting the unarmed nature of the species' scolex.^[22] Species-specific variations in external structure include size disparities, with T. solium cysts tending to be smaller and more abundant in porcine intermediate hosts, whereas T. saginata cysts are marginally larger but occur in fewer numbers within bovine musculature.^[5]^[13]

Internal Anatomy

The scolex of the cysticercus, the larval stage of Taenia species such as T. solium and T. saginata, is inverted and located within the vesicle, featuring four muscular suckers and a rostellum; in T. solium, the rostellum is armed with 22–32 hooks arranged in two rows, while in T. saginata it is unarmed.^[23] The scolex contains neural tissues for sensory functions and muscular tissues in the suckers and rostellum to facilitate attachment upon evagination in the definitive host.^[23] The vesicle, or bladder, is a translucent, fluid-filled sac lined by a germinal membrane, containing an acellular, glycogen-rich fluid that serves as an energy reserve, with no digestive system present as nutrients are absorbed osmotically through the tegument.^[23] The fluid supports the parasite's metabolism in the intermediate host, maintaining turgor pressure essential for structural integrity.^[24] Histologically, the bladder wall comprises an outer epithelial-like tegument covered in microtriches that enhance surface area for nutrient absorption, underlying smooth muscle cells, loose stroma with calcareous corpuscles, and glycogen deposits.^[23] A protonephridial system provides excretion, consisting of a network of tubular canals terminating in flame cells that filter waste from the parenchyma.^[23] These internal components collectively enable the cysticercus to remain viable within host tissues until ingestion by the definitive host triggers evagination.

Epidemiology

Global Distribution

Cysticercus, the larval stage of Taenia solium, exhibits a global distribution strongly influenced by socioeconomic conditions, including poverty, inadequate sanitation, and agricultural systems that permit free-roaming pigs in subsistence farming communities. The parasite is highly endemic in Latin America (e.g., Mexico, Brazil, and Peru), sub-Saharan Africa (e.g., Tanzania, Zambia, and Cameroon), and parts of Asia (e.g., India and China), where these factors enable widespread environmental contamination with T. solium eggs.^[3]^[1] According to the World Health Organization, T. solium taeniasis/cysticercosis is endemic in 51 countries, with an additional 14 suspected, predominantly across these continents.^[25] Prevalence data underscore the burden in these regions, with porcine cysticercosis affecting up to 30% of pigs in high-risk areas such as rural Tanzania and Mexico, highlighting the role of unregulated pig husbandry in perpetuating the cycle.^[26]^[27] In humans, neurocysticercosis—the most severe form—impacts an estimated 2.56 to 8.30 million individuals globally, including both symptomatic and asymptomatic cases, with the highest rates in endemic zones where it accounts for up to 30% of epilepsy cases.^[3] These figures are derived from serological and epidemiological surveys, emphasizing the disease's concentration in low- and middle-income settings with limited veterinary and public health infrastructure.^[28] In Europe and North America, incidence remains low due to advanced sanitation systems, strict meat inspection protocols, and confinement-based pig farming that minimize human-pig contact.^[1] Historically, cysticercosis prevalence in these developed regions declined sharply after the early 20th century, driven by mandatory meat inspections and improved hygiene practices that effectively interrupted transmission.^[29] Nonetheless, emerging cases have been reported among immigrant populations from endemic areas, with outbreaks traced to imported infections in communities in the United States and Western Europe.^[30]^[31]

Transmission Patterns

The transmission of Cysticercus, the larval stage of Taenia solium, primarily occurs through the fecal-oral route, where eggs shed in the feces of human carriers of adult tapeworms contaminate food, water, or the environment.^[1] These eggs are ingested by intermediate hosts, such as pigs, leading to the development of cysticerci in their tissues, or by humans acting as accidental intermediate hosts, resulting in human cysticercosis.^[3] Poor sanitation practices, including open defecation, exacerbate this contamination, allowing eggs to persist in soil, vegetation, or water sources accessible to both animals and people.^[1] Key risk factors for transmission include inadequate hygiene, such as improper handwashing after defecation, which facilitates the spread of eggs within households or communities. Free-roaming pigs that scavenge in areas contaminated by human feces are particularly susceptible, as they ingest eggs directly from the environment, perpetuating the cycle by harboring cysticerci in their muscles.^[3] Additionally, the consumption of undercooked pork containing viable cysticerci by humans establishes intestinal taeniasis, where carriers then excrete infectious eggs, closing the transmission loop.^[1] Autoinfection represents a direct risk for individuals already harboring adult T. solium tapeworms, occurring when they inadvertently swallow their own eggs due to poor personal hygiene. The zoonotic cycle of T. solium relies on this interplay between humans and pigs: human taeniasis carriers release eggs in feces, which pigs ingest to develop cysticerci; subsequent human consumption of infected pork meat reinfects people with the adult worm, sustaining egg production and environmental contamination.^[3] This cycle is amplified in settings where pigs are not confined and human waste management is deficient, highlighting behavioral and infrastructural factors as critical drivers of transmission.^[1]

Pathogenesis and Disease

Cysticercosis in Humans

Cysticercosis in humans occurs when individuals accidentally ingest eggs of the pork tapeworm Taenia solium, serving as intermediate hosts rather than definitive ones. The eggs hatch in the intestine, releasing oncospheres that penetrate the intestinal wall, enter the bloodstream, and migrate to various tissues, where they develop into larval cysts known as cysticerci. This condition is exclusive to T. solium, as other taeniid species like T. saginata do not produce eggs capable of causing human cysticercosis.^[32]^[3]^[2] The clinical manifestations depend on the number, location, size, and stage of the cysticerci, with neurocysticercosis—the involvement of the central nervous system—accounting for 60-90% of symptomatic cases and representing the most severe form. In neurocysticercosis, cysts commonly form in the brain parenchyma, ventricles, or subarachnoid space, leading to symptoms such as seizures (the most frequent presentation, occurring in 70-90% of cases), chronic headaches from increased intracranial pressure, and focal neurological deficits. Muscular cysticercosis involves cysts in skeletal muscles, often presenting as painless subcutaneous nodules or remaining asymptomatic, while ocular cysticercosis affects the eyes, causing vision impairment, uveitis, or blindness due to cysts in the vitreous or subretinal space. Unlike in pigs, where cysticerci predominantly localize to muscles with minimal neurological impact, human infection frequently targets the brain, resulting in profound morbidity.^[32]^[33]^[2] Pathophysiologically, viable cysticerci are typically surrounded by a host-derived fibrous capsule and elicit minimal immune response, often remaining asymptomatic for years. However, as cysts degenerate—due to natural attrition or immune attack—they release antigens, provoking a vigorous inflammatory response with eosinophils, lymphocytes, and macrophages, which causes perilesional edema, vasculitis, and tissue damage. This degeneration can lead to calcification of dead cysts, forming nodules that may act as epileptogenic foci through focal scarring. In the central nervous system, such inflammation contributes to complications like hydrocephalus from ventricular obstruction, stroke secondary to arachnoiditis and vessel occlusion, and chronic meningitis, underscoring the condition's potential for life-threatening outcomes.^[32]^[3]^[33]

Effects in Intermediate Hosts

In intermediate hosts such as pigs and cattle, cysticerci primarily localize in skeletal muscles, heart, and tongue, forming discrete cystic nodules that measure 0.5–1.5 cm in diameter and contain invaginated protoscolices. These cysts induce localized pathological changes, including fibrosis and granulomatous inflammation around degenerating larvae, leading to scar tissue formation in affected muscles; however, viable cysts typically elicit minimal host tissue disruption and remain asymptomatic in the majority of cases.^[34] In pigs, heavy infections can result in visible nodules upon palpation or slaughter inspection, often causing condemnation of entire carcasses or affected organs to prevent transmission, thereby impacting meat quality and usability.^[35] Similar effects occur in cattle harboring Taenia saginata cysticerci, though infections are generally lighter and more confined to muscle tissues. The host immune response to cysticerci in these animals involves encapsulation rather than aggressive rejection, with viable larvae surrounded by a thin collagen type I layer that limits infiltration and promotes parasite survival for months to years.^[36] Inflammation is sparse and eosinophil-dominated only during larval degeneration, typically without systemic effects unless cysts rupture, which can trigger localized granuloma formation; this modulated response allows cysts to persist asymptomatically while suppressing broader immune activation.^[36] In porcine hosts, natural Taenia solium infections have been shown to impair growth, reducing overall weight gain compared to uninfected controls, though the extent varies with parasite burden and is often subclinical.^[37] Economically, porcine cysticercosis imposes significant burdens through direct losses at slaughter, including carcass condemnation and devaluation of infected meat by 20–30%, estimated at approximately US$19.5 million annually in Mexico alone based on 2015 prevalence data.^[38] In other endemic regions like Nigeria, annual losses from condemned pigs and reduced productivity reach US$28.6 million, representing about 3% of the national pig industry value.^[39] Trade restrictions further exacerbate impacts, as pork from high-prevalence areas faces export bans or quarantines, limiting market access for smallholder farmers and hindering livestock commerce in affected countries.^[35]

Diagnosis and Management

Diagnostic Methods

Diagnosis of cysticercus infections, particularly cysticercosis caused by the larval stage of Taenia solium (in humans and pigs) or Taenia saginata (in cattle), relies on a combination of serological, imaging, and post-mortem techniques to detect the presence of cysts in humans and animal hosts.^[40] Serological tests are commonly employed for ante-mortem detection in living hosts, targeting antibodies or antigens produced in response to the parasite.^[41] Enzyme-linked immunosorbent assay (ELISA) and Western blot-based methods, such as the enzyme-linked immunoelectrotransfer blot (EITB), are primary serological approaches for identifying antibodies against cysticercus antigens in serum or cerebrospinal fluid. As of 2024, point-of-care tests using EITB-like assays have shown 98% sensitivity and 100% specificity for individuals with two or more viable or degenerating cysts.^[42] The EITB, using lentil lectin-purified glycoprotein antigens, demonstrates high sensitivity of 94-98% for neurocysticercosis cases with two or more viable cysts and 60-70% for a single cyst, with specificity near 100%.^[41] Antigen-detection ELISA, often employing monoclonal antibodies like HP10 or B158/B60, is particularly useful for confirming viable parasites, showing sensitivities ranging from 50% in parenchymal cases to higher in subarachnoid neurocysticercosis, though cross-reactivity with other helminths can occur.^[41] Overall, serological sensitivity for neurocysticercosis typically falls between 80-95%, depending on the number and viability of cysts, making these tests valuable for screening in endemic areas but requiring correlation with clinical findings.^[40]^[41] Imaging modalities provide direct visualization of cysts, aiding in assessing location, viability, and complications, especially in human neurocysticercosis.^[43] Computed tomography (CT) scans depict viable cysts as low-density lesions with minimal surrounding edema, while calcified cysts appear as hyperdense nodules, often multiple and punctate in the brain parenchyma.^[43] Magnetic resonance imaging (MRI) offers superior resolution for detecting small or early-stage cysts, showing viable forms as cystic structures isointense to cerebrospinal fluid on T1- and T2-weighted images, with the scolex visible as a hyperintense nodule; degenerating cysts exhibit ring enhancement and edema.^[43] In animals, ultrasound is effective for identifying muscular cysts in live pigs, revealing hypoechoic, fluid-filled lesions with a hyperechoic scolex in the tongue, masseter, or heart muscles, facilitating non-invasive screening before slaughter.^[44] Post-mortem examination in slaughterhouses is a standard method for detecting cysticerci in porcine and bovine hosts, focusing on routine visual and manual inspection to prevent transmission through meat consumption.^[45] For porcine cysticercosis, tongue palpation detects palpable cysts in the lingual musculature with high specificity (100%) but low sensitivity (11-25%), serving as an initial indicator.^[46] This is followed by incisions into predilection sites such as the heart, diaphragm, intercostal muscles, and masseter, where cysts appear as white, oval, fluid-filled vesicles up to 1 cm in size; full carcass dissection is the gold standard but rarely performed due to cost.^[45] Similar incision-based inspection applies to bovine cysticercosis (Cysticercus bovis), targeting the tongue, heart, and skeletal muscles, ensuring condemnation of infected carcasses.^[45] These methods, while effective for public health surveillance, miss light infections, underscoring the need for complementary serological tools.^[47]

Treatment and Prevention

The primary treatment for cysticercosis caused by viable Cysticercus larvae, particularly in neurocysticercosis, involves antiparasitic drugs such as albendazole at 15 mg/kg/day in divided doses for 8–30 days or praziquantel at 50 mg/kg/day for 10–14 days, with the choice and duration depending on cyst burden and location.^[43]^[48] To mitigate inflammation and edema resulting from cyst death, corticosteroids like dexamethasone or prednisolone are co-administered, typically starting 1–2 days before antiparasitics and continuing for the treatment duration.^[49]^[50] Surgical intervention is reserved for complications such as hydrocephalus from ventricular cysts or ocular involvement, where cyst removal or shunting may be necessary to alleviate pressure or preserve vision.^[48]^[51] Prevention of Cysticercus infection focuses on breaking the life cycle of Taenia solium through improved sanitation to reduce fecal contamination of water and soil, thereby limiting egg transmission to humans and pigs.^[3] Pig vaccination with the TSOL18 antigen has demonstrated high efficacy, achieving up to 99% protection against porcine cysticercosis in field trials when administered to piglets.^[52]^[53] Proper meat handling, including thorough cooking to an internal temperature of at least 60°C or freezing pork at -10°C for 10–14 days, effectively kills cysticerci and prevents human taeniasis.^[13] Treatment of human taeniasis carriers with niclosamide (2 g single dose for adults) or praziquantel (5–10 mg/kg single dose) is essential to eliminate adult tapeworms and reduce egg shedding.^[54]^[55] WHO-led control programs in endemic regions, such as the national initiatives in Tanzania during the 2000s and 2010s, have integrated mass drug administration with praziquantel, pig treatment, and education, resulting in approximately 50% reductions in taeniasis and porcine cysticercosis prevalence in targeted communities after multiple rounds.^[56]^[3] These efforts emphasize integrated approaches combining chemotherapy, vaccination, and sanitation improvements to achieve sustained transmission interruption.

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Nov 14, 2022 · The highest impact and the main economic losses due to porcine cysticercosis in the agricultural sector are due to condemnation of the pig ...
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The immune response elicited by the cysticerci was classified into four separate stages. In stage I the parasites were surrounded by a thin layer of collagen ...Missing: histopathology | Show results with:histopathology<|control11|><|separator|>
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Impact of naturally acquired Taenia solium cysticercosis on the ...
Another finding of practical importance is that vaccination did not reduce the weight gain of pigs but cysticercosis did (Table 6). Show abstract.
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Aug 9, 2025 · Economic losses from porcine cysticercosis were estimated at US$28.6 million, which is 3.14 % of the total pig industry. T. solium ...Missing: impact | Show results with:impact
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Jun 24, 2024 · There are two available serologic tests to detect cysticercosis. The EITB is the test preferred by CDC. Its sensitivity and specificity have been well ...Missing: ELISA Western
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Jun 6, 2018 · Antibody detection ELISAs have mostly used semipurified somatic parasite or cyst fluid antigens. Their performance in general is poor, with ...
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Ultrasound has been shown to be a valuable diagnostic tool of Cysticercus cellulosae cysticercosis in live pigs. Herrera-Garcia et al., in 2007, described the ...
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Nov 16, 2017 · The objective of this study was to evaluate the performance of tongue palpation and circulating antigen detection for the detection of porcine cysticercosis in ...
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chapter 1. meat inspection procedures
Animals are then shot at point blank range, bled and eviscerated immediately and removed to a temporary butchery for dressing, inspection and refrigeration.
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Oct 25, 2024 · We showed that the locally available tests for infection such as tongue palpation and veterinary meat inspection are not efficient at preventing ...
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Mar 22, 2024 · Several studies suggest that albendazole (conventional dosage 15 mg/kg/day in two divided doses for 15 days) may be superior to praziquantel (50 ...
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Albendazole plus either dexamethasone or prednisolone should be considered for adults and children with neurocysticercosis.
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Feb 12, 2025 · For patients with > 2 viable parenchymal cysts, the IDSA/ASTMH guidelines recommend albendazole (15 mg/kg/day) combined with praziquantel (50 mg ...
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All patients received 15 mg of albendazole per kilogram of body weight per day for four weeks. Ten patients were also treated with 100 mg of praziquantel per ...<|separator|>
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Elimination of Taenia solium transmission to pigs in a field trial of the ...
Vaccination with TSOL18 prevented any detectable infection with T. solium in pigs raised in circumstances where there was a 20% prevalence of infection in ...
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The drug of choice for tapeworm infections is praziquantel. Niclosamide can also be used, but this medicine is not available in the United States.
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May 3, 2024 · Praziquantel is the medication most often used to treat active taeniasis, given at 5-10 mg/kg orally once for adults and 5-10 mg/kg orally once for children.
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Effect of National Schistosomiasis Control Programme on Taenia ...
This study aimed to assess the effects of the National Schistosomiasis Control Programme on prevalence of taeniosis and porcine cysticercosis over a four year ...Missing: Zanzibar | Show results with:Zanzibar