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DATEM

DATEM, also known as diacetyl tartaric acid esters of mono- and diglycerides (E 472e), is a synthetic emulsifier derived from the esterification of mono- and diglycerides of fatty acids with diacetyl tartaric acid, typically sourced from plant-based oils such as palm or sunflower.^[1] This food additive functions primarily as a dough conditioner in baking, where it strengthens the gluten network, enhances dough stability during processing, and improves overall bread volume and crumb structure.^[2] In addition to baking applications, DATEM serves as an emulsifier and stabilizer in various processed foods, including cakes, biscuits, pastries, coffee whiteners, ice cream, sauces, and soups, helping to maintain texture and prevent separation of ingredients.^[3] DATEM has been evaluated for safety by international regulatory bodies, including the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which established an acceptable daily intake (ADI) of 0-50 mg/kg body weight in 2003, and the European Food Safety Authority (EFSA), which set an ADI of 240 mg/kg body weight expressed as tartaric acid in 2020, concluding no safety concerns at typical use levels due to its hydrolysis into common dietary constituents in the gastrointestinal tract.^[4]^[1] In the United States, the Food and Drug Administration (FDA) recognizes DATEM as generally recognized as safe (GRAS) for use in food under good manufacturing practices without specified limits.^[5]

Chemical Composition

Molecular Structure

DATEM, or diacetyl tartaric acid esters of mono- and diglycerides (E 472e), is defined as a mixture of esters formed by the reaction of diacetyl tartaric acid with mono- and diglycerides derived from edible fats and oils.^[5]^[4] In this structure, the glycerol backbone has one or more of its hydroxyl groups esterified with fatty acids to form the mono- and diglyceride components, while another hydroxyl group is esterified with one of the carboxyl groups of diacetyl tartaric acid.^[6] Diacetyl tartaric acid itself consists of tartaric acid with its two vicinal hydroxyl groups acetylated, giving the moiety -C(=O)-CH(OCOCH₃)-CH(OCOCH₃)-C(=O)-O- linked to the glycerol, with the remaining carboxyl group potentially free or further modified. The general structural representation can be described as follows, where R represents hydrogen or an acyl group from fatty acids (e.g., R = C(=O)(CH₂)ₙCH₃, with n typically 10–20): The glycerol core is CH₂OR-CHOR-CH₂OR', where at least one R or R' is the diacetyl tartaric acid ester, and the others are fatty acyl chains or H.^[6] This results in a complex mixture without a single fixed molecular formula, as the composition depends on the degree of esterification and chain lengths.^[5] Variations in DATEM arise primarily from the source of the fatty acids, which determine the lengths and saturation of the R groups; for example, chains from soybean oil are predominantly C18 unsaturated, while those from palm oil are mainly C16 and C18 saturated.^[6]

Physical and Chemical Properties

DATEM typically presents as a white to ivory powder, beads, or waxy solid, often with a slight yellowish tint depending on the fatty acid composition.^[7]^[8] This form facilitates its handling and incorporation into food formulations as an emulsifier.^[9] It is insoluble in cold water but can form colloidal dispersions or pastes when dispersed in warm water around 60°C; it readily dissolves in oils, ethanol, and warm fats, reflecting its amphiphilic nature.^[8]^[10] The hydrophilic-lipophilic balance (HLB) value of DATEM ranges from 8 to 9.2, providing intermediate emulsifying capability suitable for oil-in-water systems in food applications.^[11] The melting point of DATEM varies between approximately 45°C and 56°C, influenced by the chain length and saturation of the constituent fatty acids.^[12]^[13] It exhibits hydrolytic stability under neutral pH conditions but undergoes decomposition in strong acidic or basic environments due to its ester linkages.^[14] Key chemical behaviors include ester hydrolysis during baking processes, which contributes to its functionality, and reactivity with gluten proteins through ester bond formation or strong binding interactions that enhance dough strength.^[15]^[16]

Production

Raw Materials

The production of DATEM begins with mono- and diglycerides as primary components, which are derived from edible vegetable oils such as sunflower, rapeseed, palm, or soybean oils, though animal fats may also be used in some formulations.^[17] These glycerides provide the fatty acid backbone essential for the emulsifying properties of DATEM and are typically sourced from food-grade oils to ensure compatibility with final product safety.^[5] Tartaric acid, another key raw material, is exclusively the L(+)-isomer and is obtained either from natural plant sources like grapes—extracted from wine lees and argols—or synthesized via the chemical conversion of maleic anhydride.^[17] This acid undergoes acetylation with acetic anhydride to form diacetyltartaric anhydride, which is then esterified with the mono- and diglycerides.^[17] Food-grade catalysts facilitate the esterification reactions: an acidic catalyst, such as phosphoric acid, is employed for the acetylation of tartaric acid, while an alkali catalyst, like sodium hydroxide, supports the subsequent esterification step.^[17]^[18] All raw materials must adhere to strict purity standards, including those outlined in the Food Chemicals Codex (FCC) or equivalent regulations, to guarantee the absence of contaminants and suitability for food use; for instance, heavy metals and residual solvents are limited to ensure overall safety.^[5]^[19] In line with industry practices, there is a growing preference for sustainable and non-GMO sources, particularly RSPO-certified palm oil for mono- and diglycerides, to minimize environmental impact and meet consumer demands for ethical sourcing.^[20]^[21]

Manufacturing Process

The manufacturing process of DATEM begins with the acetylation of L-(+)-tartaric acid to produce diacetyltartaric anhydride. This step involves reacting tartaric acid with acetic anhydride in a weight ratio of 1.5–3.5:1, using a catalytic amount of concentrated phosphoric acid (0.004–0.005% by weight of tartaric acid). The mixture is heated to 50–55°C initially, then maintained at 80–90°C for 20–60 minutes, yielding diacetyltartaric anhydride with approximately 98% efficiency and a melting point of 120–132°C.^[22]^[23] The next phase is esterification, where the diacetyltartaric anhydride intermediate is combined with mono- and diglycerides (such as stearic acid mono-diglyceride) in a weight ratio of 2.5–4:1 relative to tartaric acid. A basic catalyst, typically powdered sodium hydroxide (0.004–0.005% by weight of tartaric acid), facilitates the reaction under vacuum conditions (-0.09 to -0.098 MPa) at 90–130°C for 20–40 minutes. Byproducts like acetic acid and water are removed via distillation at around 125°C during this process.^[22] Following esterification, byproducts such as acetic acid and water are removed via distillation under vacuum at around 125°C. The product is then dried by spray granulation at 90–110°C under normal pressure and milled into a fine powder or beads for handling and storage. Quality control measures assess parameters including acid value (60–105 mg KOH/g) and saponification value (300–550 mg KOH/g) to ensure a minimum DATEM ester content of 80%, confirming compliance with food additive standards.^[22] Industrial production of DATEM employs batch or continuous processes in facilities certified for food-grade manufacturing and compliant with Good Manufacturing Practices (GMP) to maintain purity and safety.^[23] DATEM was introduced in the mid-20th century, with commercial availability as a dough conditioner dating to 1948 in the United States, representing the third generation of advanced food emulsifiers that improved upon earlier, simpler variants.^[24]^[18]

Applications

In Bakery Products

DATEM primarily functions as a dough conditioner in bakery products, strengthening the gluten network by promoting cross-links between flour proteins, which enhances dough elasticity and improves gas retention during fermentation and baking. This interaction occurs mainly during mixing and proofing stages, where DATEM's polar groups bind to gluten proteins, while its lipophilic portions associate with starch and lipids, stabilizing the structure under baking heat.^[2]^[25]^[9] In yeast-leavened breads, DATEM is incorporated at usage levels of 0.2-0.5% based on flour weight, yielding key benefits including up to a 20% increase in loaf volume, finer and more uniform crumb structure, reduced dough stickiness for easier handling, and extended shelf life through better moisture retention and anti-staling effects. These improvements contribute to overall product consistency in commercial production.^[26]^[27]^[28] Specific applications include crusty breads like rye and baguettes, where it imparts springiness and volume; soft rolls for enhanced texture; and frozen doughs to maintain quality after thawing and proofing. DATEM is compatible with other dough conditioners, such as ascorbic acid, allowing synergistic effects in formulations. Its emulsifying properties stem from the diacetyl tartaric acid esterification of mono- and diglycerides, enabling effective protein-lipid interactions. Widely adopted since the 1960s, DATEM has become a staple in commercial baking for reliable dough performance and finished product quality.^[9]^[29]^[26]

In Other Foods

DATEM serves as an effective emulsifier and stabilizer in various non-bakery processed foods, where it helps maintain product integrity by preventing phase separation in oil-water mixtures. In coffee whiteners, DATEM stabilizes emulsions to prevent oil separation, enhances whitening ability, and improves powder dispersibility.^[30] In margarine and spreads, it improves texture and spreadability by modifying viscosity and enhancing fat crystallization rates.^[30] For ice cream, DATEM reduces ice crystal formation, controls fat agglomeration, and boosts meltdown resistance by stabilizing emulsions and acting as a seeding agent for crystallization.^[30] In confectionery products, DATEM stabilizes emulsions in fillings, chocolates, and icings by controlling viscosity, reducing stickiness, and enhancing gloss and mouthfeel.^[30] These benefits stem from DATEM's ability to enhance mouthfeel and prevent phase separation in diverse oil-water systems, contributing to improved product stability and sensory qualities, at low levels generally not exceeding regulatory limits such as quantum satis under EU Regulation (EC) No 1333/2008.^[30]^[31] While DATEM is primarily food-grade, it has limited applications as an emulsifier in cosmetics and pharmaceuticals due to its stabilizing properties in emulsions.^[32] Emerging uses include incorporation into plant-based alternatives, such as vegan creams and protein powders, where it mimics dairy textures by stabilizing plant-derived emulsions and preventing separation.^[33]

Regulatory Status and Safety

Approval and Regulations

DATEM, or diacetyl tartaric acid esters of mono- and diglycerides, was first evaluated internationally by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) in 1966, with an acceptable daily intake (ADI) of 0-25 mg/kg body weight established, later revised to 0-50 mg/kg body weight in 1974.^[34] Development of DATEM as a food emulsifier occurred during the mid-20th century, primarily in the 1950s and 1960s, to improve dough stability in baking applications.^[35] Initial regulatory approvals followed in the 1970s, aligning with growing use in commercial food production across Europe and the United States. In the United States, DATEM is affirmed as generally recognized as safe (GRAS) by the Food and Drug Administration (FDA) under 21 CFR 184.1101, with affirmation published in the Federal Register in 1989.^[5] The ingredient is permitted for use as an emulsifier, dough strengthener, and processing aid in foods such as baked goods and fats/oils, with no specified limits other than current good manufacturing practices (GMP).^[5] For labeling, the acronym "DATEM" or the full common name "diacetyl tartaric acid esters of mono- and diglycerides" must appear in the ingredient list.^[5] In the European Union, DATEM is authorized as the food additive E472e under Regulation (EC) No 1333/2008 on food additives, applicable since 2010. It is permitted at quantum satis levels—meaning as needed for technological purposes without exceeding GMP—in most food categories, including bakery wares and fine bakery wares, as detailed in Annex II of the regulation. Labeling requires declaration as "E472e" or the specific name "diacetyltartaric and fatty acid esters of glycerol" in the ingredients list. Globally, DATEM is approved under the Codex Alimentarius as INS 472e, serving as an emulsifier, stabilizer, and dough conditioner in various food categories consistent with GMP.^[36] JECFA has evaluated DATEM as safe at typical use levels, maintaining an ADI of 0-50 mg/kg body weight based on toxicological data. In Canada, it is permitted by Health Canada as a listed food additive under the Food and Drug Regulations, aligned with Codex standards and without numerical maximums beyond GMP. Similarly, in Australia and New Zealand, Food Standards Australia New Zealand (FSANZ) authorizes INS 472e in the Australia New Zealand Food Standards Code, permitting its use in processed foods at quantum satis levels. There are no general restrictions on DATEM use in conventional foods, but it is monitored and typically excluded from certified organic products, as synthetic emulsifiers are prohibited unless explicitly allowed on national organic permitted substances lists, such as the USDA National List.^[37]

Health and Safety Considerations

DATEM, or diacetyl tartaric acid esters of mono- and diglycerides (E 472e), is affirmed as generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) for use as a direct human food ingredient at levels not exceeding current good manufacturing practice. This status is based on its established safety profile, including compliance with specifications in the Food Chemicals Codex, and its applications as an emulsifier, dough conditioner, and adjuvant in various foods without specific quantity limitations beyond good manufacturing practices.^[5] Toxicological evaluations indicate that DATEM undergoes extensive hydrolysis in the gastrointestinal tract into tartaric acid, acetic acid, and mono- and diglycerides, which are normal dietary constituents metabolized or excreted without accumulation. Acute toxicity is low, with LD50 values exceeding 20 g/kg body weight in rodents and other species. Short- and long-term studies in rats and dogs at dietary levels up to 10% (approximately 5,000 mg/kg body weight/day) showed no adverse effects relevant to humans, though high doses were associated with reduced body weight gain, soft stools, and minor renal or adrenal changes in some animals; no genotoxic, reproductive, or developmental toxicity was observed. The European Food Safety Authority (EFSA) concluded no safety concerns from these data.^[1]^[14] EFSA has established an acceptable daily intake (ADI) for DATEM of 240 mg/kg body weight per day, expressed as tartaric acid, based on the metabolism of its tartaric acid component and applying an uncertainty factor to human data. The Joint FAO/WHO Expert Committee on Food Additives (JECFA) has established an ADI of 0–50 mg/kg body weight. Estimated dietary exposure from its use in bakery products and other foods ranges from 0.1 to 18 mg/kg body weight per day across population groups, well below the ADI, leading to conclusions of no safety concern at authorized levels in the European Union. Similarly, the FDA's GRAS affirmation supports unrestricted use under good manufacturing practices, with no reported human health risks or allergies attributed to DATEM at typical consumption levels.^[1]^[38]

References

[1]
and diglycerides of fatty acids (E 472a‐f) as food additives - EFSA
Mar 11, 2020 · Exposure estimates were calculated for all food additives individually, except for E 472e and f, using maximum level, refined exposure and food ...Missing: FDA | Show results with:FDA
[2]
DATEM | Baking Ingredients - BAKERpedia
DATEM is an emulsifier used in bread making to strengthen the dough during processing. It helps improve texture and increase volume.
[3]
[PDF] DIACETYLTARTARIC AND FATTY ACID ESTERS OF GLYCEROL
JECFA (2001). SYNONYMS. Diacetyltartaric acid esters of mono- and diglycerides, DATEM; INS No. 472e; Tartaric, acetic and fatty acid esters of glycerol ...Missing: E472e | Show results with:E472e
[4]
diacetyl tartaric and fatty acid esters of glycerol - INCHEM
Groups of five male Han Wistar rats were fed semi-purified diets containing DATEM (E472e; acid value, 100 mg/g and saponification value, 500 mg/g, expressed ...
[5]
DIACETYLTARTARIC and FATTY ACID ESTERS of GLYCEROL
INS No. 472e: Diacetyltartaric acid esters of mono- and diglycerides; datem; INS No. 472f: Tartaric, acetic and fatty acid esters of glycerol, mixed; ...Missing: E472e | Show results with:E472e
[6]
21 CFR 184.1101 -- Diacetyl tartaric acid esters of mono - eCFR
Diacetyl tartaric acid esters of mono- and diglycerides, also known as DATEM, are composed of mixed esters of glycerin in which one or more of the hydroxyl ...
[7]
Diacetyltartaric and fatty acid esters of glycerol
Diacetyltartaric acid esters of mono- and diglycerides, DATEM, INS No. 472e ... Structural formula. The majors components are: in which. 1) one or two of ...
[8]
DATEM MSDS-FOODCHEM
1.2. Description: DATEM is a diacetyl tartaric acid ester manufactured through chemical synthesis. 1.3. Chemical Formula: Not Applicable; 1.4. Molecular weight: ...
[9]
Diacetyl Tartaric Acid Esters of Mono and Diglycerides TDS.
Aug 19, 2019 · Diacetyl Tartaric Acid Esters of Mono and Diglycerides (DATEM) is made from edible vegetable oil( palm oil), this emulsifier is used in food( bakery, non- ...
[10]
Diacetyl Tartaric Acid Ester of Mono- and Diglycerides (DATEM)
Diacetyl tartaric acid esters of mono- and diglycerides of fatty acids, or simply DATEM, is an emulsifier used in breadmaking to strengthen the dough structure ...Missing: formula | Show results with:formula
[11]
Datem Diacetyl Tartaric Acid Esters of Mono and Diglycerides E 472e
This food additive is considered the best emulsifier for strengthening the gluten network in bread dough. Benefits in Bread. * By strengthening the gluten ...
[12]
Modulation of coconut oil crystallization by DATEM and glycerol ...
Aug 1, 2025 · ... (HLB) values (DATEM, HLB 8–9.2; GM, HLB 3–6). Usually, emulsifiers with higher HLB are more suitable for oil-in-water emulsions. Additionally ...<|control11|><|separator|>
[13]
DATEM (Diacetyl Tartaric Acid Esters of Mono - Chemsino
Its melting range is approximately 45°C. It has an HLB value of 8.0-9.2 and a distinct acetic acid odor. DATEM can disperse in hot water, mix with fats and oils ...
[14]
RADIAMULS DATEM 2004K - Oleon
... Melting Point: 51 - 56 °C. Used in. Food. Ice Cream & Creamers; Plant-Based Drinks; Instant Powder. Key performances in global. Emulsion stability booster.
[15]
Abstract - Interactions of DATEM with gluten
DATEM (diacetyl tartaric acid esters of monoglycerides) improve the ... In addition DATEM was found to get firmly bound to the residual gluten proteins ...<|control11|><|separator|>
[16]
Gluten Conformation at Different Temperatures and Additive ... - NIH
Feb 1, 2022 · An anionic surfactant such as DATEM can be incorporated into the gluten protein by using its lipophilic moiety to interact with hydrophobic ...
[17]
Re‐evaluation of acetic acid, lactic acid, citric acid, tartaric acid ...
Mar 11, 2020 · First, tartaric acid reacts with acetic anhydride using an acidic catalyst in order to form diacetyltartaric anhydride and acetic acid. Second, ...
[18]
Method for the preparation of diacetyl tartaric acid esters of mono ...
Mar 8, 2012 · A thesis named “Preparation of Food Emulsifier DATEM” (Journal of ... food grade silicon dioxide and tricalcium phosphate. [0025]. The ...
[19]
Food Chemicals Codex (FCC) | FCC | Online
The Food Chemicals Codex is a compendium of internationally recognized standards for determining the purity and quality of food ingredients.FCC Forum · Notices · FCC Publication and... · FCC Errata Table
[20]
Palm-based Power: A DATEM Substitute for Affordable, Quality Bread
May 2, 2023 · From sustainable palm-based sources. Our multi-purpose bread emulsifier has a lower environmental impact and is naturally GMO ...
[21]
datem emulsifier ingredient marketing - Knowledge
Feb 21, 2023 · DATEM emulsifier is a food grade emulsifier which provides all-natural, non-GMO solutions, derived from vegetable sources such as sunflower oil ...Missing: raw | Show results with:raw
[22]
Process for preparing diacetytartaric esters of mono-, di-glycerides
In the step c, stearic acid mono-diglyceride is added to an intermediate product containing diacetyl tartaric anhydride, and powdered sodium hydroxide is used ...
[23]
and diacetyltartaric, mixed acetic and tartaric acids esters of mono
According to the IBO, the levels of toxic elements in E 472a are mainly dependent on their concentrations in the raw materials used in the manufacturing process ...<|separator|>
[24]
What Are the Uses of DATEM (E472e) in Food Production - Chemsino
Mar 27, 2024 · ... HLB value of 8.0. DATEM emulsifier has a distinctive acetic acid odor, disperses in hot water, and is miscible with fats. It dissolves in ...
[25]
Rheological Characteristics of Gluten after Modified by DATEM ...
Aug 6, 2025 · A higher compliance elasticity during recovery suggested higher recoverable energy stored by a more cross-linked gluten than the control sample.
[26]
What is DATEM (E472e) in Bread? Made of, Uses, Safety, Side effects
Dec 12, 2019 · DATEM is a synthetic emulsifier made from the esterification of acetic acid, tartaric acid, glycerol and fatty acids. It can also be produced ...
[27]
Successful Sale Of 2tons DATEM Emulsifier To An Indonesian Bakery
Jun 20, 2024 · Using DATEM emulsifier, bread volume increased by 20%, shelf life extended by 30%, and product marketability improved.Missing: loaf | Show results with:loaf
[28]
Food Additives and Processing Aids used in Breadmaking
It exhibits higher hydrophilicity when compared to monoand diglycerides (Gioia et al., 2017) . The incorporation of 0.4% DATEM increases the loaf volume by ...
[29]
Improvement of whole wheat dough and bread properties by ...
Polysorbate 60 resulted in a tight, thick gluten film, which may be because DATEM interacts with gluten primarily through hydrophobic interactions, whereas ...
[30]
[PDF] Food Emulsifiers and Their Applications - E-Book´s
Synthetic emulsifiers have only come into wide commercial use in the second half of the twentieth century. Their development was driven by the processed ...
[31]
DATEM Market Research Report 2033 - Growth Market Reports
DATEM is also used in dairy, confectionery, fats and oils, pharmaceuticals, and cosmetics for its emulsifying and stabilizing properties. Table Of Content.Datem Market Outlook · Product Type Analysis · Application Analysis<|control11|><|separator|>
[32]
what emulsifiers are used in vegan protein powders and coffee ...
Aug 2, 2023 · DATEM, or diacetyl tartaric acid ester of mono- and diglycerides, is a common emulsifier used in plant-based powders, such as vegan protein ...
[33]
[PDF] and Diglycerides (Datem E 472e) (expressed on 13 June 1997)
Nov 24, 2016 · DATEM (E 472e) is an emulsifier, used in mother's milk substitutes and FSMPs, with an ADI of 0-50 mg/kg bw. It is being re-evaluated for use in ...Missing: EFSA | Show results with:EFSA
[34]
Diacetyl Tartaric Esters of Monoglycerides (DATEM) and Associated ...
DATEM are esters of polyvalent alcohols that consist of glycerol derivates esterified with edible fatty acids and mono-and diacetyl tartaric acids.<|control11|><|separator|>
[35]
Diacetyltartaric and fatty acid esters of glycerol (472e)
Tartaric, acetic and fatty acid esters of glycerol, mixed;. Functional Classes. Emulsifier; Sequestrant; Stabilizer. JECFA Lookup Click here to search the FAO ...Missing: E472e | Show results with:E472e
[36]
The National List | Agricultural Marketing Service - USDA
In organic crop production, nonsynthetic (natural) substances are allowed unless specifically prohibited and synthetic substances are prohibited unless ...Missing: DATEM | Show results with:DATEM
[37]
Diacetyltartaric acid esters of mono- and di-glycerides
DATEM. Diacetyltartaric acid esters of mono- and di-glycerides ... INS number: 472e. Contact. For questions and feedback, send us an email to jecfa@fao.org ...Missing: ADI | Show results with:ADI