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Interstate 64

Interstate 64 (I-64) is an east–west Interstate Highway in the that spans 963.52 miles (1,550.64 km) from its western terminus at an interchange with , , and U.S. Route 61 in , to its eastern terminus at the Bowers Hill Interchange with and near . The route traverses six states—, , , , , and —serving as a vital corridor for interstate commerce and travel across the Midwest and Mid-Atlantic regions. Designated as part of the National System of Interstate and Defense Highways, I-64 facilitates connections between major urban centers and supports economic activity in manufacturing, agriculture, and port-related industries. The highway begins in suburban St. Louis, Missouri, where it briefly runs concurrent with U.S. Route 40 and U.S. Route 61 before crossing the into near Collinsville. In , I-64 extends 130.4 miles (209.9 km) eastward through the region and , bypassing cities like Belleville and en route to the state line. Entering , the 124-mile (200 km) segment passes through Evansville and the southwestern part of the state, crossing the into via the near Louisville. In , I-64 covers 191 miles (307 km), linking Louisville, , and Frankfort while traversing the and . Continuing into West Virginia for 188.75 miles (303.76 km), I-64 follows the Ohio River near Huntington before ascending through the Appalachian Mountains, paralleling the Kanawha River to Charleston and passing through Beckley and White Sulphur Springs. In Virginia, the longest segment at 299 miles (481 km) serves as the state's primary east–west corridor, extending from the West Virginia border through Roanoke, Charlottesville, and Richmond to the Hampton Roads metropolitan area. Here, it integrates with the Hampton Roads Beltway (I-64/I-664) and provides access to Norfolk, Newport News, and the Port of Virginia, one of the busiest container ports on the East Coast. Throughout its length, I-64 features modern infrastructure, including multi-lane divided sections, but has undergone major reconstructions, such as the $535 million rehabilitation in St. Louis completed in 2009 to improve safety and capacity.

Route description

Missouri

Interstate 64's western terminus is located at a with I-70, US 40, and US 61 in Wentzville, St. Charles County. From this point, the highway proceeds eastward as a four-lane freeway concurrent with US 40, traversing rural landscapes in western St. Charles County before entering the western suburbs of the metropolitan area. The Missouri segment spans 40.6 miles (65.3 km) in total, ending at the Illinois state line across the Poplar Street Bridge over the . The route features a major interchange with MO 94 near Weldon Spring, providing access to local communities and the August A. Busch Memorial Conservation Area. Further east, I-64 intersects I-270 near via a , facilitating connectivity to the broader region and serving commuters traveling to and from the city's western suburbs. This connection enhances the highway's role as a vital link for regional traffic, including access to business districts and residential areas in and Town and Country. Throughout its Missouri course, I-64 crosses flat Midwestern plains with negligible elevation changes, typical of the region's topography, and passes over the Missouri River via the Daniel Boone Bridge east of Weldon Spring. The highway continues eastward into Illinois, where it begins a much longer rural and urban traversal across the state.

Illinois

Interstate 64 enters Illinois from Missouri across the Mississippi River via the Poplar Street Bridge, landing in East St. Louis in St. Clair County. From there, the highway heads east-northeast through southern Illinois as a primarily rural corridor, bypassing urban areas like O'Fallon and Shiloh while traversing expansive farmland. It spans 130.4 miles (209.9 km) across the state, providing a key diagonal connection between the St. Louis metropolitan area and points east. For much of its length, I-64 runs concurrently with , overlapping from the state line eastward through and Fayette counties before diverging near Effingham. The route features several significant river crossings, including the southeast of Nashville in and the adjacent to White County near the border. The terrain remains predominantly flat to gently rolling agricultural land, with limited development except for brief urban sections around Mt. Vernon in County and Effingham in Effingham County. Notable interchanges include the western terminus junction with I-55 in , the crossover with I-70 at mile marker 19 near in Madison County, and the intersection with I-57 at mile marker 96 south of Mt. Vernon in Jefferson County. These connections facilitate regional travel, linking I-64 to north-south corridors serving and beyond. The segment concludes with an exit into across the near Grayville.

Indiana

Interstate 64 enters from near Grayville, crossing the via the Wabash Memorial Bridge into Posey County near . This initial segment spans 18.04 miles (29.04 km) through the flat to rolling hills of the Wabash Valley, running parallel to the southern border of the state. The highway provides essential connectivity for the Evansville metropolitan area, offering direct access via the nearby interchange with (formerly including I-164) in northern Vanderburgh County. Throughout this portion, I-64 traverses Posey and Vanderburgh counties, serving as a key east-west corridor for regional travel and commerce. Major interchanges include the connection with at exit 25 in Vanderburgh County, facilitating north-south travel toward Evansville, and the junction with I-69 at exit 29 near Haubstadt, which links to the city's core and beyond. The route's alignment supports efficient movement through agricultural and semi-rural landscapes, with rest areas available for travelers shortly after entering the state. From Haubstadt, I-64 continues eastward for approximately 105 miles through central and , passing through rural areas in Warrick, Spencer, Dubois, , Washington, Scott, and counties. The route traverses gently rolling terrain and forested regions, including portions of the near Paoli, with interchanges providing access to communities such as Boonville (exit 39, SR 62), (exit 63, SR 162), and (exit 99, SR 60). Near the end, in County, it intersects SR 62 at exit 118 and SR 256 at exit 122 before reaching New Albany. This segment ultimately leads across the into via the .

Kentucky

Interstate 64 enters Kentucky from Indiana across the Ohio River via the double-decked Sherman Minton Bridge, linking New Albany, Indiana, with Louisville, Kentucky, and carrying six lanes of I-64 and U.S. Route 150 traffic. The segment spans 191.5 miles (308.2 km) eastward through the state, serving as a primary east-west corridor connecting major urban centers including Louisville, Frankfort, Lexington, and the gateway to the Appalachians via the Daniel Boone National Forest. This route traverses Kentucky's diverse landscapes, from the urban industrial areas along the Ohio River to the fertile Bluegrass plains renowned for horse breeding, before ascending into the rolling hills of the Knobs region. In Louisville, I-64 follows the Riverfront Expressway along the Ohio River's north bank, providing access to the city's downtown and port facilities through a series of urban interchanges. A key feature is the Kennedy Interchange, where I-64 meets I-65 to the south and I-71 to the north, forming one of the nation's busiest highway junctions and enabling seamless connections to Nashville, , and . Eastward from Louisville, the freeway passes through suburban Jefferson County and Shelby County, intersecting Kentucky Route 53 near Shelbyville and U.S. Route 60 near Frankfort, while crossing the via a multi-span bridge that highlights the route's engineering over the state's waterways. Northeast of Frankfort, I-64 winds through the heart of the , characterized by open farmlands and equestrian estates, before reaching , Kentucky's second-largest city. Here, it forms a critical junction with I-75 at exit 115, supporting commerce and travel between the Bluegrass and surrounding states. The highway briefly cosigns with U.S. Route 60 northwest of , aligning with historic travel paths through horse country. Further east near , I-64 interchanges with at exit 126, facilitating access to rural communities and bourbon distilleries. As it progresses, the terrain shifts from flat plains to the undulating hills of , with multiple crossings of the via elevated viaducts amid forested bluffs. Approaching the eastern end of its Kentucky segment, I-64 enters the near Stanton, navigating steeper grades and rock cuts as it transitions toward the foothills. This portion emphasizes the route's role in linking Kentucky's central economic hubs to and beyond, ultimately connecting to through the Big Sandy River valley.

West Virginia

Interstate 64 enters from near Huntington by crossing the Big Sandy River at Kenova, marking the start of its 189-mile (304 km) traversal eastward through the state. The highway initially serves the Huntington metropolitan area, providing access to the ports and industrial facilities before heading northeast toward the state capital of . From there, I-64 overlaps with the tolled West Virginia Turnpike (cosigned with I-77) southeastward through the Kanawha Valley to Beckley, then continues independently east through the to White Sulphur Springs near the border. The route contends with the rugged terrain, featuring steep grades—such as the ascent up Sandstone Mountain—and extensive earthwork including cuts and fills to navigate narrow mountain ridges and deep river valleys like those of the Kanawha and New rivers, which I-64 spans via multiple bridges. While no major tunnels are present on this segment, the highway's alignment prioritizes efficient passage through the hilly landscape, supporting for West Virginia's operations in the southern coalfields and chemical manufacturing hubs concentrated in the "Chemical Valley" around and Huntington. Key interchanges along I-64 include the complex junction with I-77 at the eastern edge of Charleston (exit 99), where the routes cosign for approximately 64 miles along the Turnpike through Fayette and Raleigh counties to Beckley; the exit for US 119 (exit 129) just east of Beckley, facilitating access to local mining and commercial areas; and near White Sulphur Springs (exit 175), where it intersects US 60 and briefly cosigns with it before crossing into Virginia. Beyond the state line, I-64 proceeds into Virginia's Shenandoah Valley.

Virginia

Interstate 64 enters from near the community of White Sulphur Springs, crossing the state line in Alleghany County and descending into the Allegheny Highlands before reaching the . The highway spans 299.07 miles (481.30 km) eastward through the state, the longest segment of its total route. In the , I-64 follows relatively flat plains, overlapping with for approximately 30 miles from near through Staunton, providing access to agricultural areas and small towns. From Staunton, I-64 veers southeast, passing through Waynesboro and crossing into the region with its rolling hills, en route to Charlottesville, where it intersects and serves the , a major educational institution founded in 1819. Continuing east, the route traverses the 's varied terrain, crossing the multiple times, including via bridges in the Richmond area, before reaching the state capital of . In , I-64 briefly overlaps with Interstate 95 and connects to the I-295 bypass, facilitating travel around the urban core while serving historic sites such as those associated with the . Further east, the highway enters the Tidewater flats, passing through Williamsburg—a key colonial historic site with preserved 18th-century architecture—and the metropolitan area, supporting ports in and Newport News that handle significant international cargo. Major interchanges along the route include the junction with I-81 near Staunton for north-south connectivity, I-95 near for links to , and the I-295 bypass to alleviate city traffic. Near Charlottesville, I-64 is cosigned with for a segment, aiding local travel. The highway concludes its Virginia traversal at the interchange with I-664 and in Chesapeake, integrating with the regional auxiliary beltway system.

History

Planning and designation

The planning for Interstate 64 originated with the National Interregional Highway Committee's 1944 report, Interregional Highways, which recommended a 33,920-mile national system of limited-access express highways to connect major population centers and facilitate commerce, including the corridor that would become I-64 from the eastward to the Atlantic coast. This vision built on earlier federal efforts to modernize the nation's roadways amid growing post-World War II traffic demands. The further advanced these plans by directing the Bureau of Public Roads to finalize route locations, resulting in the "Yellow Book" publication that mapped the 41,000-mile Interstate System, with I-64's alignment influenced by existing major roads and estimated at over 800 miles in total length. The provided the funding and authorization for the Interstate System, including I-64, leading to its full completion by 1988. In August 1957, the American Association of State Highway Officials (AASHO) formally designated the route as I-64 during its annual meeting in , assigning even numbers to east-west primary interstates and positioning it as a key trans-Appalachian link from near , , across the Midwest and South to . The numbering followed a logical grid where lower even numbers ran farther north, placing I-64 south of I-40 to serve southern industrial and port regions. This designation marked the official integration of the route into the emerging Interstate System, prioritizing connectivity between agricultural heartlands and coastal ports. Routing I-64 through the presented major engineering and logistical challenges, particularly in and , where debates centered on balancing direct east-west access with the region's steep , narrow valleys, and limited existing , often requiring extensive tunneling, bridging, and land acquisition. These discussions influenced alignments to minimize environmental disruption while maximizing economic benefits for isolated communities, drawing from the Yellow Book's emphasis on feasible paths over U.S. Route 60 and related corridors. State-level planning varied by region. In Missouri and Illinois, I-64's development was closely tied to upgrading segments of U.S. Route 40, the historic "National Road" from toward the , leveraging existing alignments to expedite federal funding and construction approvals. In , efforts focused on linking directly to the ports on the Atlantic coast, enhancing trade access and urban connectivity in the Tidewater area.

Construction

Construction of Interstate 64 began in the late with initial segments in , building upon the planning framework established in the 1950s for the national . The original roadway in was developed in sections through the early 1960s, primarily upgrading existing alignments to freeway standards. In , much of the route followed upgrades to , with new construction in the southern portion completed in 1974. Kentucky's portion saw early progress in the 1960s, with the section from Ashland (Boyd County) to Huntington opening in November 1964, facilitating better connectivity across the . The route from Louisville to advanced through the decade, with key interchanges like the I-64/I-75 in becoming operational by the late 1960s. Full completion across the state occurred by the mid-1970s, including the controversial Cochran Hill Tunnels under Cherokee Park, which opened in 1970, and the West Louisville segment finalized around 1974. In , construction commenced with the first contract awarded in Cabell County in 1957, near Huntington. The segment from Huntington to was substantially complete by 1966, incorporating bridges over the built to initial interstate standards. However, the rugged terrain posed significant challenges, including extensive tunneling, grading through mountains, and environmental reviews that caused delays in the 1970s, particularly for corridors H and G under the . These issues, including environmental impact statements for sensitive areas, postponed final segments until the late 1980s, with the route from Sam to Beckley opening in July 1988, marking statewide completion. Virginia's construction accelerated in the for the central corridor, with the section from Staunton (near I-81) to Waynesboro opening in 1970, followed by the extension to Afton Mountain in September 1971. The route reached by the mid-1970s, including the I-95/I-64 interchange operational since 1968, providing a vital east-west link through the region. Extensions to in the 1980s completed the eastern terminus, highlighted by the opening of the initial 1.2-mile segment of I-664 connecting to I-64 in Hampton on June 25, 1981. By the late 1980s, most of I-64 was operational across its 964-mile length, with West Virginia's final segment in 1988 achieving substantial completion for the main route. The Missouri-Illinois connection via the Poplar Street Bridge saw enhancements beginning with environmental studies in 1992, ensuring full interstate continuity across the .

Current status and projects

Completed recent projects

In , the "New I-64" project, launched in 2000, involved a $535 million rebuild of approximately 12 miles of the highway from near I-270 to near I-55 in the area. This design-build initiative added lanes, reconstructed 30 bridges, and improved interchanges to enhance capacity and safety, with full completion in July 2010, ahead of schedule and $11 million under budget. In , expansions to the Bridge-Tunnel approaches on I-64 during the 2010s focused on increasing capacity through interchange improvements. Phase I of the I-64/I-264 interchange project, completed in , widened I-64 westbound between the Twin Bridges and the I-264 ramps, adding lanes and reconfiguring ramps to reduce congestion and improve access to the bridge-tunnel corridor. The Kanawha Valley upgrades from 2005 to 2015 included widening and bridge improvements near to boost flood resilience. The I-64 Dunbar/South Bridge project rehabilitated and widened bridges over the , expanding I-64 from mile marker 96.0 to 99.3 and adding multi-lane capacity, with construction completed in 2010 at a cost of $93.6 million. These completed projects have collectively reduced in key urban segments of I-64 by increasing lane capacity and modernizing .

Ongoing and planned improvements

In , the I-64 widening project in the region continues as a major capacity expansion effort, adding a third general-purpose lane in each direction along with auxiliary lanes from the New Kent/James City County line eastward toward York County. This multi-segment initiative, which began construction in 2022, addresses chronic on approximately 12 miles of the corridor and includes improvements to interchanges and shoulders for enhanced safety and reliability. The project is divided into phases, with Segment C focusing on the eastern portion and featuring traffic shifts implemented in early 2025 to accommodate ongoing work; full completion is anticipated by late 2027. In , upgrades to the I-64/I-77 interchange near Beckley emphasize safety improvements for heavy truck traffic along the . The ongoing widening project, valued at $140 million, involves pavement rehabilitation, base reinforcement, resurfacing, and lane additions on I-64 westbound from mile marker 121.5 to 40 and I-77 northbound, reducing potholes and enhancing durability for commercial vehicles. Initiated in March 2024 with phased lane closures, the work incorporates overnight operations and detours to minimize disruptions, with substantial progress reported through 2025 and final completion targeted for late 2026. Kentucky's planning for the I-64/Mountain Parkway extension advances with a focus on realigning segments to improve and regional connectivity in eastern . The Mountain Parkway Expansion project, which extends the four-lane highway from its current terminus near I-64 toward U.S. 23, includes the final 13-mile Magoffin-Floyd segment featuring new alignments, bridges, and interchanges to reduce curves and enhance safety. Construction on this phase commenced in August 2025, building on prior segments, with environmental reviews and engineering studies emphasizing long-term efficiency; completion of the extension is projected beyond 2027 pending funding approvals. At the Illinois-Indiana border, rehabilitation of the I-64 crossing addresses structural vulnerabilities through replacement and reinforcements. The $136 million replaces the eastbound span, built in the , with a modern structure while traffic utilizes the existing westbound during construction. Work, which passed its one-year mark in August 2025, includes foundation strengthening against scour and seismic risks, with the new eastbound slated for opening around 2028 followed by of the old structure into 2029. In , the conceptual study for intelligent transportation systems (ITS) along I-64 in the area evaluates real-time options from Jefferson Avenue to Kingshighway, where the “New I-64 project” ended in 2009. This initiative integrates sensors, cameras, and variable message signs to monitor , incidents, and weather. Tied to broader conceptual planning, the ITS enhancements support upcoming bridge reconstructions starting in 2026 and improve for the urban interstate segment. Many of these I-64 improvements are supported by funding from the (IIJA), which allocates billions for highway resilience and modernization, including $25 million specifically for Virginia's I-64 widening segments. Projects incorporate measures, such as elevated structures and flood-resistant designs, in response to events like the 2020 Midwest floods that disrupted portions of the route in and .

Auxiliary routes

I-264

Interstate 264 (I-264) is an auxiliary Interstate Highway in southeastern Virginia, serving as a key urban connector in the Hampton Roads region as part of the broader auxiliary system linked to the mainline I-64. The route spans approximately 25 miles (40 km) from its western terminus at the complex interchange with I-64 and I-664 near Bowers Hill in Chesapeake to its eastern end at Parks Avenue in the resort area of Virginia Beach. It functions primarily as a radial freeway spur, providing high-speed, limited-access travel through the cities of Chesapeake, Portsmouth, Norfolk, and Virginia Beach, while accommodating both commuter and tourist traffic. The highway's path begins at the Bowers Hill interchange, where it branches eastward from the Hampton Roads Beltway, passing through industrial and residential areas in Chesapeake and before entering via the tolled Downtown Tunnel under the Elizabeth River. In , I-264 links downtown districts and the Ocean View neighborhood, supporting access to major naval facilities such as the in and . Continuing east, it transitions into Virginia Beach, connecting suburban developments, , and the Oceanfront beach district, where it terminates as a freeway at Parks Avenue near 21st Street. Portions of the route feature high-occupancy vehicle (HOV) lanes to manage peak-hour congestion, and it parallels sections of while intersecting U.S. Route 13 at Military Highway. Key interchanges along I-264 include the western Bowers Hill junction with I-64 and I-664, which handles significant regional traffic volumes, and the eastern I-64 interchange near and the Virginia Beach city line. In , a major connection occurs at Exit 13 with U.S. Route 13 (Military Highway), serving military and commercial corridors. Other notable exits facilitate access to Virginia Beach's Independence Boulevard (Exit 17) and First Colonial Road (Exit 21A), which provide direct routes to and the coastal beaches. Designated as an Interstate in the late for its original segment between the two I-64 interchanges, I-264's signage and full integration were established by 1971, with the eastern extension to Beach completed as Virginia Route 44 (the Virginia Beach-Norfolk Expressway) and later incorporated into the Interstate system in 1999. Initially built as a four-lane opening in 1967, the route underwent expansions in the and to six or eight lanes to accommodate growing suburban development and tourism to the Beach resort area, with tolls removed in 1995 following bond retirement. These improvements enhanced capacity for seasonal beach traffic, solidifying its role in regional connectivity.

I-464

Interstate 464 (I-464) is a 5.67-mile (9.12 km) auxiliary Interstate Highway in southeastern that serves as a connector between Interstate 64 (I-64) in Chesapeake and Interstate 264 (I-264) in . The route functions primarily as an urban freeway linking the metropolitan area, facilitating access to industrial zones, port facilities, and key regional corridors. It integrates briefly with approaches to I-64's eastern terminus by providing a direct southward link from the Beltway. The highway begins at a cloverleaf interchange with I-64 and U.S. Route 17 (US 17) near Bowers Hill in Chesapeake, where it heads northeast as a six-lane divided freeway paralleling the Southern Branch of the Elizabeth River. It passes through industrial and commercial areas, interchanging with State Route 168 (the Chesapeake Expressway) and U.S. Route 13 before entering the tolled Downtown Tunnel beneath the Elizabeth River. Emerging in Norfolk's Berkley neighborhood, I-464 continues briefly as a four- to six-lane freeway, interchanging with State Route 337 before ending at a partial cloverleaf with I-264 near the Ghent district. Throughout its length, the route supports freight movement to the Port of Virginia and connects to surrounding urban infrastructure without serving recreational or coastal destinations. Construction of I-464 occurred in phases as part of 's original Interstate plans from the late 1950s. The initial 0.85-mile segment from I-64 to US 13 opened on May 31, 1967, coinciding with the completion of nearby I-64 sections. Further extensions followed, with the portion from US 13 to State Route 337 opening in 1987 and the final link from State Route 337 to I-264 completed in May 1989, marking the route's full operational status. The Downtown Tunnel, integral to the crossing, was incorporated during these later phases and remains a toll facility managed by the . In the 2010s, improvements focused on interchange enhancements rather than major widening of the mainline, which was largely built to six lanes. Notable projects included ramp modifications at the I-64/I-464 junction near Bowers Hill to improve and , with studies and designs advancing into the . As of 2025, construction on these ramp modifications began in February and is scheduled for completion in summer 2026. These efforts address growing congestion in the without altering the route's core urban freeway character.

I-564

Interstate 564 (I-564) is a short auxiliary in the U.S. state of , providing direct access from the mainline Interstate 64 (I-64) in to . Measuring 2.77 miles (4.46 km) in length, it branches westward from I-64 in the area and follows Admiral Taussig Boulevard through urban coastal terrain toward the . The route primarily facilitates and personnel movement to the world's largest , with its design emphasizing efficient connectivity for defense-related traffic. The highway features a flat profile typical of the Tidewater region's low-lying geography, including a brief 680-foot tunnel under a runway at the naval station to accommodate aviation operations. Along its path, I-564 includes three interchanges: an exit to Terminal Boulevard (State Route 406) serving nearby industrial areas, an interchange with Little Creek Road (State Route 165) providing local access, and a final entrance to the naval base itself. The eastern terminus connects directly to I-64 at exit 276, marking the route's only major Interstate interchange and integrating it seamlessly into the broader Hampton Roads freeway network. Planning for I-564 began in 1958 as part of Virginia's original Interstate Highway proposals, with construction occurring in phases from the mid-1970s onward. The initial segment from I-64 to Terminal Boulevard opened in June 1971, followed by an extension to Little Creek Road in November 1974, and the full route to the was completed on August 4, 1977. Due to its specialized role in supporting naval operations, the highway has undergone minimal major modifications since completion, though recent projects have added HOV lanes and addressed local congestion without altering its core alignment. In parts near the base, access is coordinated with security protocols, reflecting its exclusive focus on military-related use.

I-664

Interstate 664 (I-664) is a 20.69-mile (33.30 km) auxiliary in southeastern that forms the western segment of the Beltway, providing a semicircular bypass route from its northern terminus at I-64 in Hampton to its southern terminus at the I-64/I-264 interchange in Chesapeake. This route connects key industrial and port facilities in the region, including access to and the Port of Virginia, facilitating the movement of freight and commercial goods across the area. As part of the beltway system, I-664 closes the loop around the eastern end of mainline I-64, offering an alternative path for traffic avoiding central congestion. The highway begins at the I-64 interchange in Hampton and proceeds southward through Newport News, where it serves urban and industrial zones before crossing Hampton Roads Harbor via the toll-free Monitor-Merrimac Memorial Bridge-Tunnel (MMMBT), a 4.6-mile (7.4 km) facility combining bridge spans and a submerged tunnel section. After emerging on the south side in , I-664 continues through rural and suburban areas of and into Chesapeake, passing near port terminals and providing connectivity to operations. The route emphasizes freight efficiency, with approximately 6% of its traffic consisting of trucks supporting regional commerce and . Major interchanges along I-664 include its northern end at I-64 in Hampton (mile 0), the Bowers Hill Interchange complex in Chesapeake where it meets I-64 and I-264 (mile 20), and US 17 near (Exit 1), which provides access to local roads and the broader network toward . The route also features connections to VA 164 in vicinity via I-264, enhancing links to naval and shipping infrastructure. Construction of I-664 was completed in April 1992, with the opening of the MMMBT marking the final link in the beltway and enabling full connectivity between Hampton and Chesapeake. Initial segments, including the Hampton-Newport News portion, opened in 1981, while the Suffolk-Chesapeake extension was finished in 1990. In the , expansions focused on freight capacity, including the 2012 Interstate 64 Peninsula Study recommending improvements for truck traffic and the ongoing Bowers Hill Interchange enhancements to alleviate congestion at key junctions.

Junction list

Western portion (Missouri–Kentucky)

The junction list for Interstate 64's western portion spans the flatlands and river crossings of , , , and western , facilitating access to urban centers like , Evansville, and Louisville through primarily level terrain interchanges. As of November 2025, exit numbering follows mile-based conventions starting at the western terminus in each state, with no renumberings reported from recent widening or bridge projects in this segment.
miExitDestinationsNotes
Missouri
0.0001A-BI-70 / US 40 / US 61 – St. Louis, Kansas City, WentzvilleWestern terminus; interchange with I-70 east to St. Louis and I-70/US 40 west to Kansas City; signed as exits 1A (west) and 1B (east)
11CProspect Road – Lake St. Louis
22Lake St. Louis Blvd – Lake St. Louis
44Route 364 – Lake St. Louis
66Route DD / Wing Haven Blvd – O'Fallon
99Route 94 – St. Charles, Defiance
1111Research Park Circle – St. Charles
1414Chesterfield Airport Road – Chesterfield
1717Boone's Crossing – Chesterfield
19A19AChesterfield Parkway – ChesterfieldEastbound only
19B19BRoute 340 / Olive Blvd / Clarkson Rd – Chesterfield
2121Timberlake Manor Parkway – Chesterfield
21.221Missouri RiverDaniel Boone Bridge
2222Route 141 – Chesterfield
2424Mason Rd – Chesterfield
2626Ballas Rd – St. Louis
2727Spoede Rd – St. Louis
28A28AUS 67 – St. Louis
3030McKnight Road – St. Louis
31B31BI-170 north / Brentwood Blvd / McCutcheon Rd / Hanley Rd – Richmond Heights
33A33ABig Bend Blvd – St. Louis
33B33BBellevue Avenue – St. Louis
33C33CMcCausland Avenue – St. Louis
34B34BHampton Avenue / Oakland Avenue – St. Louis
36A36AKingshighway Blvd – St. Louis
36C36CVandeventer Avenue – St. Louis
37A37ABernard St / Market St – St. Louis
37B37BGrand Blvd – St. Louis
38A38AJefferson Ave – St. Louis
38B38B20th St / Chestnut – St. Louis
39B39B14th St – St. Louis
39C39C11th St / Stadium – St. Louis
40B40BSouth 6th St – St. Louis
4040I-44 / US 61 / US 67 – Tulsa OK, SpringfieldEastern end of US 61 / US 67 concurrency
Illinois
0.00Continuation from Missouri
3A3AMartin Luther King Jr. Drive – East St. LouisEastbound exit only
3B3B25th Street – East St. LouisWestbound exit and eastbound entrance
44Illinois 15 – East St. Louis, Belleville
6648th Street – Washington Park
99Route 159 – Caseyville, Collinsville
1212Illinois 159 – Belleville, Collinsville
1414US 50 – O'Fallon
1616Green Mount Road – Shiloh, O'Fallon
1919Illinois 4 – Mascoutah
2121Route 161 – Shiloh, Lebanon
2323Green Mount Road – Belleville
2424Dupo, Millstadt
2727Illinois 158 – Waterloo, Smithton
3030Horseshoe Lake Road – French Village
3434Center Street – Pontoon Beach
4141Illinois 111 – Roxana, Hartford
4646Illinois 255 north – Alton
5252Illinois 143 – Wood River, Bethalto
6060Illinois 111 – Alton, Godfrey
6363Illinois 3 – Alton, Grafton
7272US 67 – Godfrey, Jerseyville
9292Illinois 100 – White Hall, Kampsville
105105Illinois 16 – Carrollton, Hardin
110110US 67 – White Hall, Carrollton
130130Continuation into Indiana
Indiana
0.00Continuation from Illinois
44SR 69 south – New Harmony, Mount Vernon
77SR 68 – Mount Vernon
1818SR 62 – Mount Vernon
2525US 41 – Evansville
29A29AI-69 south / SR 57 – Evansville, Henderson KYSouthern terminus of I-69
29B29BSR 57 – Evansville
3939SR 61 – Lynnville
5454SR 61 – Holland
5757US 231 – Dale
6363SR 162 – Santa Claus
7272US 150 / SR 62 – New Albany
7979SR 37 – French Lick
105105SR 135 – Corydon
123123I-265 / SR 62 – New Albany, Louisville KY
124Continuation into KentuckyOhio River crossing (Sherman Minton Bridge)
Kentucky
0.00Continuation from Indiana
1A1AI-64 west to I-65 – Louisville KYWestbound exit and eastbound entrance; I-64/I-65/I-71 interchange
1B1BI-64 east to I-71 – Louisville KYEastbound exit and westbound entrance; I-64/I-65/I-71 interchange
44I-265 / KY 841 – Gene Snyder Fwy, Louisville
55US 150 / 22nd St – Louisville
99I-265 / KY 841 – Louisville
1212KY 1931 / New Cut Rd – Louisville
1515Hurstbourne Pkwy – Louisville
1717Blankenbaker Pkwy – Louisville
1919I-265 / KY 841 – Louisville
2828KY 1848 – Simpsonville
3232KY 53 – Shelbyville, Finchville
3535I-71 – Louisville, Cincinnati OH
4242KY 714 – Frankfort
4848US 60 – Frankfort
5353US 127 – Frankfort, Owen
6262KY 388 – Midway
6767KY 33 – Versailles
7575US 60 – VersaillesEastern end of US 60 concurrency
8080KY 4 / KY 922 – Lexington
8787US 27 / KY 67 – Paris
9494KY 1961 – Lexington
104104KY 4 Loop – LexingtonWestern beltway
110110US 60 – Lexington
115115I-75 / US 421 – Lexington, Cincinnati OH
118118KY 4 / New Circle Rd – Lexington
120120US 27 / North Broadway – Lexington
122122US 68 / KY 353 – Lexington
125125Russell Cave Rd – Lexington
130130KY 1973 – Georgetown
136136KY 353 – Leestown
142142KY 1009 – Midway
148148KY 420 – Frankfort
155155US 127 / KY 17 – Owenton
163163KY 36 – Owenton
170170KY 355 – Williamstown
176176KY 22 – Berry
179179KY 11 / Mountain Pkwy east – Stanton, Natural Bridge State ParkEastern terminus of Mountain Parkway Spur
184184KY 15 – Stanton, Campton
188188KY 114 – Slade, Red River Gorge
191Continuation into West Virginia
This table provides a complete list of interchanges in flat and riverine areas, such as the Mississippi and Ohio River crossings, with concurrencies noted for major routes like US 40/US 61 in Missouri.

Eastern portion (West Virginia–Virginia)

Interstate 64 enters West Virginia from Kentucky at mile 0 and proceeds eastward approximately 189 miles to the Virginia state line, navigating the rugged Appalachian terrain with significant elevation changes and interchanges serving industrial, urban, and recreational areas. In Virginia, the highway restarts its numbering at exit 1 near the state line and extends about 300 miles to its eastern terminus at the junction with I-264 in Chesapeake, transitioning from mountainous regions to the densely populated Hampton Roads metropolitan area. Key connections include I-77 near Beckley, West Virginia, for southern access, and I-95 near Richmond, Virginia, for connections to Washington, D.C., and points south. As of November 2025, widening projects have been completed in segments such as mile markers 204.9 to 215.6 east of Richmond to address congestion and improve safety. The exit numbers in both states are primarily mile-based, approximating the distance from the western state line. The following tables detail the interchanges, drawing from official state transportation department data.

West Virginia Exits

ExitDestinationsNotes
1US 52 South / WV 75 – Kenova, Ceredo (Tri-State Airport)Western terminus entry from Kentucky
6US 52 North – Huntington, Ironton, OH (VA Medical Center, Central City Antique District)
8WV 152 South / WV 527 North – 5th Street East (Huntington, Huntington Museum of Art)
10Welcome Center / Rest Area (eastbound only)
11WV 10 – Hal Greer Boulevard / Downtown (Huntington, Marshall University, Civic Center)
15US 60 – 29th Street East (Barboursville, Football Stadium)
18US 60 / To WV 2 – Merritts Creek Road / Barboursville
20US 60 – Barboursville / Mall Road (westbound only)
20AUS 60 – West Mall Road (eastbound only)
20BUS 60 – East Mall Road (eastbound only)
28US 60 – Milton
34County Route 19 – Hurricane
37Rest Area (both directions)
39WV 34 – Winfield / Teays Valley (Scott Depot)
40Under constructionAs of 2025 updates
44US 35 – St. Albans
45WV 25 – Nitro (Poca)
47WV 622 – Goff Mountain Road / Cross Lanes (westbound only; Dog Race Track)
47AWV 622 South – Goff Mountain Road (eastbound only; Dog Race Track)
47BWV 622 North – Cross Lanes (eastbound only)
50WV 25 – Institute (WV State University, Rehab Center)
53WV 25 – Dunbar / Roxalana Road
54US 60 / To WV 601 – MacCorkle Avenue / Jefferson Road (South Charleston, Marshall University Graduate College)
55To WV 601 – Kanawha Turnpike (westbound only)
56Montrose Drive (South Charleston, Marshall University Graduate College)
58AUS 119 South – Oakwood Road / Logan
58BUS 119 North – Virginia Street / Civic Center (Charleston; eastbound only)
58CUS 60 – Lee Street / Civic Center (eastbound exit)
58CUS 60 – Washington Street / Civic Center (westbound exit)
87WV 25 – Elkview
91US 119 – South Charleston
97WV 601 – Cabin Creek
98County Route 8/1 – Pinch
99I-77 north / WV 114 – Greenbrier Street / State Capitol (Charleston; Yeager Airport)Northern end of I-77 concurrency; urban interchange
100I-77 south / US 119 – Daniel Boone Park (Charleston)Southern end of I-77 concurrency
101WV 601 – Big Chimney
106County Route 21 – Sissonville
114WV 17 – Charleston
121County Route 7 – Stanaford
124US 19 – Eisenhower Drive / Beckley
125WV 307 – Airport Road / Beaver (Raleigh County Memorial Airport; westbound only)
125AWV 307 – Beaver (eastbound only)
125BAirport Road (Raleigh County Memorial Airport; eastbound only)
129County Route 9 – Shady Spring / Grandview Road (New River Gorge National River, Grandview Park; westbound only)Steep grades in vicinity
129ACounty Route 9 South – Shady Spring (eastbound only)
129BCounty Route 9 North – Grandview Road (New River Gorge National River – Grandview State Park; eastbound only)
133County Route 27 – Pluto Road / Bragg
139WV 20 – Sandstone / Hinton (Hinton Historical District, Pipestem State Park)
143WV 20 – Green Sulphur Springs / Meadow Bridge (Rainelle)
150County Route 29/4 – Dawson
156US 60 – Midland Trail / Sam Black Church (Rupert – Rainelle)
161WV 12 – Alta (Alderson / Pence Springs)
169US 219 – Lewisburg / Ronceverte (Greenbrier Valley Airport, Lewisburg Historical District, Osteopathic Medical School, State Fairgrounds)
175US 60 / WV 92 – White Sulphur Springs / Caldwell (Greenbrier State Forest, National Radio Astronomy Observatory, Cass Scenic Railroad, Resort / Ski Areas)
178Welcome Center / Rest Area (westbound only)
181US 60 / WV 92 – White Sulphur Springs (National Radio Astronomy Observatory, Resort / Ski Areas; westbound exit only)Eastern state line approach

Virginia Exits

ExitIntersectsCity/CountyNotes
1Jerry's Run TrailAlleghany CountyEntry from West Virginia; mountainous terrain
7Route 661Callaghan area, Alleghany County
10Routes 60 / 159Covington area / Hump Back Bridge, Alleghany County
14West Jackson StreetCovington, Alleghany County
16Routes 60 / 220Covington / Mallow Mall, Alleghany County
21Route 696Low Moor / Selma, Alleghany County
24Routes 60 / 220 / 384Clifton Forge / Dabney Lancaster Country Club, Alleghany County
27Routes 60 / 220 / 629Clifton Forge / Iron Gate, Alleghany County
29Routes 42 / 269Nicelytown, Alleghany County
35Route 269 / 850Longdale Furnace, Alleghany County
43Route 780George Washington National Forest / Goshen, Rockbridge County
50Routes 60 / 623Lexington / Kerr’s Creek, Rockbridge County
55Route 11Lexington / Virginia Horse Center, Rockbridge County
56I-81 SouthLexington and points south, Rockbridge CountyAuxiliary connection
87I-81 NorthStaunton and points north, Augusta CountyAuxiliary connection; mile-based restart near I-81 overlap
91Route 608Stuarts Draft / Augusta Hospital, Augusta County
94Route 340Waynesboro, Augusta County
96Route 624Lyndhurst, Augusta County
99Route 250Afton Mountain, Augusta CountySteep grades on Afton Mountain
107Route 250Albemarle County
114Route 637Albemarle County
118Route 29Albemarle County
120Route 631Albemarle County
121Route 20Albemarle County
124Route 250Albemarle County
129Route 616Albemarle County
136Route 15Louisa County
143Route 208Louisa County
148Route 605Goochland County
152Route 629Goochland County
159Route 522Louisa County
167Route 617Goochland County
173Route 623Goochland County
175Route 288To Chesterfield County, Goochland County
177I-295To I-95, downtown Richmond bypass, Henrico CountyAuxiliary connection
178Route 250Broad Street, Henrico County
180Gaskins RoadHenrico County
181Parham RoadHenrico CountyRecent interchange improvements completed in 2025
183Route 250Broad / Glenside, Henrico County
185Route 33Staples Mill Road, Henrico County
186I-195 SouthTo Powhite Parkway, Henrico County
187I-95 NorthTo Ashland and points north, Henrico CountyMajor auxiliary connection
190I-95 SouthTo Petersburg and points south, Henrico CountyMajor auxiliary connection
192Route 360 / Mechanicsville TurnpikeMechanicsville, Henrico County
193Route 33 / Nine Mile RoadHighland Springs, Henrico County
195Laburnum AvenueRichmond Raceway, Henrico County
197Airport DriveRichmond International Airport, Henrico County
200I-295Western intersection with I-64, Henrico CountyAuxiliary connection
205Route 249New Kent CountyWidening completed in 2025
211Route 106New Kent County
214Route 155New Kent County
220Route 33Eltham, New Kent County
227Route 30Toano, James City County
231Routes 30 / 607York River State Park, James City County
234Route 646Lightfoot, York County
238Route 143Williamsburg / Camp Peary, York County
242Route 199Colonial Parkway, York County
243Route 143Busch Gardens, York County
247Route 143Newport News, York County
247Route 238Yorktown Battlefield, Newport News
250Route 105 / Fort Eustis BoulevardFort Eustis, Newport News
255Route 143 / Jefferson AvenueNewport News, Newport News
256Oyster Point RoadNewport News, Newport News
258Route 17 / J. Clyde Morris BoulevardNewport News, Newport News
261Hampton Roads Center ParkwayHamptonCoastal interchange
262Route 134 / Magruder BoulevardHampton
263Route 258 / Mercury BoulevardHampton
264I-664To Suffolk, HamptonAuxiliary connection; Hampton Roads Beltway
265A, BRoute 134 / 167 Armistead / LaSalleHampton
265CRip Rap RoadHampton
267Routes 60 / 143 Tyler Street / County StreetHampton
268Route 169 / Mallory StreetHampton
272Bayville / Ocean ViewNorfolk
273Route 60 / 4th View StreetNorfolk
274Bay AvenueNorfolk
276A, BI-564 / Route 460 / Granby StreetNorfolkAuxiliary connection
276CRoute 165 / Little Creek RoadNorfolk
277Route 168 / Tidewater DriveNorfolk
278Route 194 / Chesapeake BoulevardNorfolk
279Route 247 / Norview AvenueNorfolk
281A, BRobin Hood Road / Route 165 / Military HighwayNorfolk
282Routes 13 / 166 Northampton BoulevardNorfolk
284I-264NorfolkAuxiliary connection
286Route 407 / Indian River RoadVirginia Beach
289Greenbrier ParkwayChesapeake
290Route 168 / Battlefield BoulevardChesapeake
291I-464 / Route 104ChesapeakeAuxiliary connection; ramp improvements completed in 2025
292Route 190 / Dominion BoulevardChesapeake
296Route 17 / George Washington HighwayChesapeake
297Routes 13 / 460 Military HighwayChesapeake
299I-264ChesapeakeEastern terminus; Hampton Roads Beltway junction