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UFC 281

UFC 281: Adesanya vs. Pereira was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on November 12, 2022, at Madison Square Garden in New York City, New York. The event was headlined by a UFC Middleweight Championship bout featuring defending champion Israel Adesanya against Alex Pereira, a former two-division Glory Kickboxing champion who had previously defeated Adesanya twice in kickboxing. In the co-main event, UFC Women's Strawweight Champion defended her title against former champion . Pereira captured the title by defeating Adesanya via technical knockout (punches) at 2:01 of the fifth round, marking his first UFC championship. Zhang reclaimed the strawweight title with a submission victory (rear-naked choke) over Esparza at 1:05 of the second round. The main card also included a lightweight clash between Dustin Poirier and Michael Chandler, which Poirier won by rear-naked choke submission at 2:00 of the second round, as well as welterweight bout between Colby Covington and Bryan Barberena, and a flyweight matchup featuring Erin Blanchfield against Molly McCann. UFC 281 drew an announced attendance of 20,845 and generated a live gate of $11,562,807, making it one of the promotion's highest-grossing events at the venue.

Event Details

Date and Venue

UFC 281 took place on November 12, 2022. The event was held at in , New York, . This iconic venue, known for hosting major combat sports events, features a main arena with a capacity of approximately 20,000 spectators for UFC bouts. The event drew a sold-out crowd of 20,845 attendees and generated a reported gate revenue of $11,562,807, marking it as one of the promotion's highest-grossing events at the venue. In the , the early preliminary card began at 6:00 p.m. , followed by the preliminary card at 8:00 p.m. , and the main card at 10:00 p.m. . This timing aligned with UFC's tradition of staging major events in , often at .

Promotion and Broadcast

UFC 281 was promoted under the banner "Adesanya vs. Pereira," highlighting the storied rivalry between champion and challenger , who had previously defeated Adesanya twice in bouts (once by in 2016 and once by knockout in 2017) under the banner. This narrative of a kickboxing grudge match transitioning to the UFC formed the core of the event's marketing, positioning it as a high-stakes redemption opportunity for Adesanya. The event's broadcast was handled through ESPN platforms in the United States, with the main card airing exclusively on pay-per-view starting at 10 p.m. ET, the preliminary card on and at 8 p.m. ET, and early prelims on at 6 p.m. ET. Internationally, the full card was available via , ensuring global accessibility for fans. Production featured a commentary team led by play-by-play announcer , with color analysis from —returning after a brief hiatus—and former two-division champion , providing expert insights during the telecast. Additional elements included fighters' selected walkout music, such as James Brown's "" for and AC/DC's "Thunderstruck" for , alongside in-arena hype videos to amplify the atmosphere at . Marketing efforts included the UFC Embedded vlog series, with episodes released in the week leading up to the event that focused on the Adesanya-Pereira preparation, including sessions and moments to build anticipation. Promotional posters, featuring the rivals in intense standoffs, and trailers emphasizing their history were unveiled in October to drive ticket sales and interest. The event reportedly generated approximately 600,000 buys, bolstering the UFC's annual revenue amid a strong performance.

Background

Historical Context

Mixed martial arts was legalized in New York State on April 14, 2016, when Governor Andrew Cuomo signed legislation making the state the 50th and final U.S. jurisdiction to permit professional MMA competitions, ending a nearly two-decade ban. This paved the way for the Ultimate Fighting Championship to host its inaugural event in the state, UFC 205, on November 12, 2016, at Madison Square Garden in New York City. UFC 281 marked the organization's sixth numbered event at the iconic venue since legalization, following UFC 205, UFC 217 in 2017, UFC 230 in 2018, UFC 244 in 2019, and UFC 268 in 2021, underscoring Madison Square Garden's status as a premier destination for major UFC cards amid the promotion's expansion in the Northeast. In the middleweight division, had held the UFC championship since capturing the vacant title with a second-round of Robert Whittaker at on October 6, 2019. Entering UFC 281, Adesanya had completed five successful defenses, defeating by decision at in March 2020, Paulo Costa via second-round at in September 2020, Marvin Vettori by unanimous decision at in June 2021, Whittaker in a rematch by second-round at in February 2022, and Sean Strickland by first-round at in July 2022, establishing him as one of the division's most dominant champions during a period of high-stakes matchmaking. The women's strawweight division leading into UFC 281 featured recent turbulence, with reclaiming the title via split decision over at on May 7, 2022, marking her return to championship status after nearly four years away from the belt she first won in 2014. This victory capped a series of rapid title exchanges in the division, including Namajunas' losses and Weili Zhang's prior reign, highlighting the competitive depth among top contenders. UFC 281, the 281st numbered event in the promotion's history, occurred amid a robust 2022 schedule that saw 42 total events as the UFC continued its post-COVID-19 recovery with full-capacity crowds and surging popularity. The year featured record-breaking attendance figures, including 20,845 fans at UFC 281 itself—the highest for any 2022 event—and contributed to the promotion's busiest fall slate with consecutive pay-per-views in , , and , reflecting sustained growth in live gates and global viewership after pandemic restrictions lifted.

Key Matchups and Storylines

The main event of UFC 281 featured a highly anticipated middleweight title clash between champion and challenger , announced on August 5, 2022. The matchup stemmed from their shared history in Glory of Heroes, where Pereira defeated Adesanya twice—first by on April 2, 2016, in , , and then by third-round on March 4, 2017, in São Paulo, . These prior encounters added a layer of personal rivalry, with Adesanya seeking redemption in after Pereira's successful UFC debut earlier in 2022. The co-main event pitted strawweight champion against former titleholder , officially targeted for UFC 281 following reports on August 18, 2022. This bout arose after Zhang's unanimous decision loss to at in September 2021, positioning her as the top contender for Esparza's belt won earlier that year. The pairing highlighted contrasting styles, with Esparza's prowess challenging Zhang's striking and resilience in a bid to reclaim divisional supremacy. Undercard developments bolstered the event's appeal, including the addition of a lightweight showdown between and on September 7, 2022, as a high-stakes clash between top-ranked contenders. Other key bouts, such as bantamweight matchup versus , were finalized around October 6, 2022, rounding out a card rich in veteran experience and emerging talent. These additions emphasized stylistic contrasts and career milestones, contributing to the event's narrative depth. The card experienced no major injuries or replacements leading up to the event, allowing the announced lineup to proceed intact despite minor undisclosed ailments reported by some fighters. Notably, entered the bout with clear retirement intentions, having expressed a desire for one final appearance to cap his Hall of Fame career. Press activities amplified the event's tension, particularly during media day on November 9, 2022, at , where Adesanya and Pereira engaged in heated verbal exchanges, reigniting their rivalry with pointed banter about past defeats and current stakes. These interactions underscored the personal animosity driving the main event, drawing significant media attention ahead of the November 12 .

Results

Main Card

The main card of UFC 281 featured five high-profile bouts, headlined by a title fight and a strawweight title rematch, all broadcast on . In the main event, challenged for the UFC championship. Despite trailing on the scorecards after four rounds, Pereira mounted a stunning comeback, dropping Adesanya with a left hook and finishing him with ground-and-pound punches for a victory at 2:01 of the fifth round, claiming the title. The co-main event saw face for the women's strawweight title. Weili, who had lost the belt to Esparza in 2020, dominated with superior grappling, securing a rear-naked choke submission at 1:05 of the second round to regain the championship. A lightweight clash pitted against . After two competitive rounds marked by heavy striking exchanges, Poirier capitalized on a scramble in the third, locking in a rear-naked choke for the submission win at 2:00. In the bantamweight bout, faced . Gutierrez landed a knee that dropped Edgar, following up with punches for a victory at 2:01 of the first round. Opening the main card, took on at lightweight. Hooker countered a takedown attempt with a head kick that rendered Puelles unable to continue, earning a win at 4:06 of the second round.

Preliminary Card

The preliminary card of UFC 281, aired on , consisted of four competitive bouts across multiple weight classes, setting the stage for the evening's higher-profile matchups with a blend of technical and striking exchanges. These fights highlighted emerging talents and veteran performers, contributing to the event's overall momentum at . In the bout, submitted via rear-naked choke at 3:20 of the first round. Moicano took the back after a scramble and locked in the choke, forcing the tap. The women's flyweight bout saw submit via armbar at 3:37 of the first round, extending her unbeaten streak in the UFC to four fights. Blanchfield capitalized on a scramble, transitioning to the armbar for the quick finish. delivered a quick finish in the light heavyweight division, stopping by (punches) at 3:44 of the first round. After an initial feeling-out process, Ulberg unleashed a flurry of heavy strikes against the cage that overwhelmed Negumereanu, prompting referee intervention as the fighter slumped to the mat, earning Ulberg his second UFC win in emphatic fashion. Closing the ESPN portion, Andre Petroski defeated Wellington Turman by unanimous decision (30-27, 30-27, 29-28) in their middleweight clash. Petroski controlled the fight with grappling and effective striking over three rounds.

Early Preliminary Card

The early preliminary card of UFC 281 featured four competitive bouts that opened the event on November 12, 2022, at in , streamed exclusively on ESPN+ and starting at 6:00 p.m. ET. These matchups showcased a mix of established veterans and rising prospects across , women's strawweight, , and divisions, setting the tone for the night's action with quick finishes and hard-fought decisions. In the lightweight opener, secured a stunning upset victory over via knockout with a left hook at 2:30 of the first round. The , fighting in front of his home crowd for the first time at the iconic venue, capitalized on Azaitar's aggressive style by countering effectively after absorbing early pressure, marking his third win in four UFC appearances. The women's strawweight clash saw former title challenger edge out promotional newcomer Silvana Gomez Juarez by unanimous decision (29-28, 29-28, 29-28). Kowalkiewicz controlled the pace with superior wrestling and grappling over three rounds, outlanding her opponent in significant strikes while defending takedown attempts, extending her win streak to two and providing a much-needed rebound after recent setbacks. Featherweight action delivered one of the night's most memorable moments as overcame a wild exchange to defeat by (punches) at 4:51 of the first round. The fight began with a rare simultaneous knockdown from simultaneous left hooks, but Trizano recovered first, swarming Choi with ground-and-pound strikes to force the stoppage in a bout that highlighted both fighters' resilience and striking power. Closing the early prelims, contender outpointed via (30-27, 30-27, 29-28). Jackson used his reach advantage and precise counterstriking to build a lead, including a significant knockdown in the third round that sealed the victory, improving his UFC record to 4-1 while handing Arce his first loss inside the promotion.

Post-Event

Bonus Awards

Following UFC 281, the promotion awarded its standard post-fight bonuses to recognize standout performances, with each recipient earning $50,000 for either a Performance of the Night or Fight of the Night honor. These awards, based on UFC criteria emphasizing exciting finishes and highly competitive bouts, were announced during the post-fight on November 12, 2022. Alex Pereira received Performance of the Night for his fifth-round victory over in the main event, securing the UFC with a devastating and follow-up strikes. Similarly, earned the same award for her second-round submission of in the co-main event, reclaiming the UFC women's strawweight championship via rear-naked choke. The Fight of the Night went to and for their clash, a three-round battle marked by intense exchanges that ended with Poirier's rear-naked choke submission in the final frame. In total, the event distributed a $200,000 bonus pool across these four awards, highlighting key moments from the main card.

Immediate Aftermath

The main event at UFC 281 saw defeat via fifth-round TKO, claiming the UFC championship and marking the first time a Brazilian fighter had held the title since Anderson Silva's reign ended in 2013. In the co-main event, submitted in the second round to reclaim the women's strawweight title, ending Esparza's second reign after 189 days. Following his loss to via first-round on the main card, former UFC lightweight champion announced his retirement from , concluding a 17-year professional career that included Hall of Fame-worthy accomplishments across multiple divisions. At the post-fight , Adesanya displayed by congratulating Pereira and reflecting calmly on the defeat, stating he felt "compromised" during the bout but harbored no bitterness toward his rival. Newly crowned champion Pereira expressed gratitude for the opportunity while hinting at ambitions beyond , though he did not specify immediate opponents. UFC President lauded the event as one of the strongest cards of , highlighting the dramatic title finishes and overall quality of the fights at . Media coverage immediately hailed UFC 281 for its two decisive title changes via stoppage, with outlets like describing it as one of the year's top spectacles due to the high-stakes drama and endings. Initial reports estimated the event generated approximately 600,000 buys, making it the only UFC card in to surpass 500,000 purchases and underscoring its commercial viability. The issued medical suspensions for 20 fighters following the event, with Adesanya receiving an indefinite suspension pending neurological clearance due to the loss, while Pereira was also indefinitely suspended as a precaution despite emerging unscathed. Other suspensions were relatively minor, including 45-day terms for fighters like Gutierrez and Esparza for cuts and impacts, reflecting the event's physical toll but no major long-term concerns.

Long-Term Impact

Title Division Changes

UFC 281 marked a pivotal shift in two weight classes, as both the and women's strawweight titles changed hands in the main and co-main events, respectively, altering championship lineages and contender landscapes. Alex Pereira's fifth-round knockout victory over defending champion ended Adesanya's second reign, which had begun with his win over at in 2019 and included five successful defenses. Entering the bout with a 23-1 MMA record, Adesanya suffered his second professional defeat, paving the way for Pereira to claim the vacant throne after dropping Adesanya with a left hook and finishing with ground strikes at 2:01 of the round. In the co-main event, reclaimed the women's strawweight title via second-round rear-naked choke submission against at 1:05, avenging the indirect path to title loss through Esparza's prior victory over , who had dethroned Weili in 2021. In the middleweight division, Pereira's triumph immediately elevated him to status, setting the stage for his sole title defense against Adesanya in a high-stakes rematch at on April 8, 2023, where Adesanya reclaimed the belt via second-round at 4:21. This quick turnaround underscored the rivalry's intensity but also highlighted Pereira's transitional role, as his loss prompted a move to , where he captured the vacant title by second-round TKO over at on November 11, 2023. Adesanya's post-UFC 281 path included the rematch victory, followed by a unanimous decision loss to at in September 2023, a decision loss to at in January 2024, reclaiming the belt via fourth-round against du Plessis at UFC 305 in August 2024, and a second-round of at UFC Fight Night on February 1, 2025. For the women's strawweight division, Weili's dominant performance reestablished her as the premier force, launching a series of successful defenses that solidified her reign. She first retained the title against via at in April 2023, followed by a win over at in August 2023, and a victory against at in April 2024. These defenses not only avenged her prior setbacks but also positioned Weili as a cornerstone of the division, with Esparza dropping out of immediate contention after the loss. The event's outcomes rippled through contender rankings, with Pereira ascending to No. 1 in the official UFC rankings and entering the men's pound-for-pound top 10 at No. 7 immediately after UFC 281. Weili, meanwhile, climbed to No. 1 in the women's pound-for-pound rankings post-event, reflecting her reclaimed dominance and briefly holding the overall women's top spot before further achievements. Historically, UFC 281 became the first card since in December 2015 to feature two title changes in its top bouts, emphasizing the event's significance in simultaneously reshaping multiple divisions.

Fighter Career Trajectories

Alex Pereira's victory over Israel Adesanya at UFC 281 marked his ascension to the UFC middleweight championship, but his subsequent title defense at UFC 287 in April 2023 ended in a second-round knockout loss to Adesanya, prompting a shift to the light heavyweight division. There, Pereira captured the vacant light heavyweight title with a second-round knockout of Jiří Procházka at UFC 295 in November 2023, followed by successful defenses against Jamahal Hill at UFC 300 in April 2024, a third-round TKO of Jamahal Hill at UFC 303 in June 2024, and a fourth-round TKO against Khalil Rountree Jr. at UFC 307 in October 2024. His reign faced a setback with a first-round TKO loss to Magomed Ankalaev at UFC 313 in April 2025, but Pereira reclaimed momentum by knocking out Ankalaev in the first round during their rematch at UFC 320 on October 4, 2025, solidifying his status as a two-division champion and extending his influence beyond the middleweight landscape initially unlocked by UFC 281. Israel Adesanya's defeat to Pereira at UFC 281 ended his second reign, yet it fueled a redemption arc as he recaptured the title via second-round at in April 2023. However, consecutive losses followed: a unanimous decision to at in September 2023 and another to at in January 2024, leading to a period of reflection and limited activity through much of 2024. Adesanya returned decisively at UFC 305 in August 2024, avenging his loss to du Plessis with a fourth-round to reclaim the belt, and extended his resurgence with a second-round of at UFC Fight Night on February 1, 2025, reaffirming his elite standing despite the pivotal setback at UFC 281. Zhang Weili's submission victory (rear-naked choke) over at UFC 281 reclaimed the women's strawweight title and underscored her resilience, setting the stage for a series of defenses that cemented her as the division's premier force. She retained the belt against via at in May 2023 and against via at in April 2024, showcasing her and striking prowess in high-stakes bouts. Further solidifying her legacy, Weili defended against via at UFC 312 on February 8, 2025, before vacating the strawweight title on October 25, 2025, to pursue opportunities in the flyweight division, where she lost the title fight to via at UFC 322 on November 15, 2025. Dustin Poirier's third-round submission win over at UFC 281 revitalized his contention, leading to a BMF title loss via fifth-round submission to at in July 2023 and a second-round victory over Benoit at in March 2024. He challenged for the championship against at UFC 302 in June 2024, falling short via fifth-round submission, which intensified retirement discussions amid his storied career. Poirier concluded his UFC tenure in a trilogy bout against for the symbolic BMF belt at UFC 318 on July 19, 2025, losing by unanimous decision and officially retiring thereafter, with the UFC 281 triumph serving as a high point in his later-year resurgence. Michael Chandler's knockout loss to Poirier at UFC 281 hampered his momentum, resulting in a unanimous decision defeat to in their rematch at UFC 309 on November 16, 2024, despite prior successes like his submission win over in May 2022. He rebounded with a third-round knockout of at UFC 314 on April 12, 2025, injecting new life into his pursuit of marquee matchups, including ongoing interest in a bout with , though no such fight materialized by late 2025. The UFC 281 outcome redirected Chandler's trajectory toward selective, high-profile engagements amid a mixed record in the division. Erin Blanchfield's second-round submission (armbar) of at UFC 281 propelled her up the women's flyweight ranks, where she amassed wins over via in March 2023 and via second-round submission in November 2023, positioning her as a top contender. A loss to in March 2024 temporarily stalled her ascent, but she responded with victories over Karine Silva in July 2024 and others, challenging for the title against at UFC 310 in December 2024, which she lost by decision, yet maintained her trajectory toward contention with a 14-2 record as of November 2025. The early UFC 281 exposure accelerated her path from prospect to perennial top-five fighter. Frankie Edgar's first-round knockout loss to at UFC 281 prompted his immediate from MMA after a Hall of Fame-worthy career, shifting his focus to family and occasional coaching roles without a return to the by November 2025. Plans for a debut against at BKFC 82 on October 4, 2025, were scrapped due to medical clearance issues just days prior, leaving Edgar's post-UFC 281 involvement limited to and non-competitive pursuits in combat sports.

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