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B Positive

B Positive is an television series that premiered on on , 2020, and concluded after two seasons on March 10, 2022. Created by and executive produced by , the series centers on Drew Dunbar, a recently divorced and father facing , who reconnects with Gina Dabrowski, a former acquaintance from his time volunteering at a , leading her to donate one of her kidneys to him. The show blends humor with heartfelt explorations of , friendship, family dynamics, and personal redemption, drawing inspiration from a real-life shared by Pennette about his own kidney transplant experience. The main cast features as the anxious yet endearing Drew, as the bold and resilient Gina, as Gina's free-spirited best friend Gabby, as Drew's ex-wife Julia, and Izzy G. as their teenage daughter Maddie, with recurring roles filled by notable actors including , , and . Produced in the multi-camera format typical of Lorre's comedies, B Positive was filmed in front of a live and aired 34 episodes across its run, maintaining a lighthearted tone while addressing serious health issues without veering into melodrama. Despite positive critical reception for its charming leads and fresh premise—earning an 85% approval rating for its first season on —the series was canceled by in May 2022 due to declining viewership, though it found a dedicated audience for its optimistic and relatable storytelling.

Cast and characters

Main cast

Thomas Middleditch portrays Drew Dunbar, a recently divorced therapist and father grappling with end-stage renal disease who requires a kidney transplant to survive. Middleditch, recognized for his Emmy-nominated performance as the anxious tech entrepreneur Richard Hendricks in HBO's Silicon Valley, brings sharp comedic timing and vulnerability to Drew, highlighting the character's internal conflicts amid health challenges and personal reinvention. Annaleigh Ashford stars as Gina Dabrowski, a free-spirited, working-class nurse's aide living in her mother's basement who impulsively offers to donate her to Drew after reconnecting with him from high . Ashford, an Emmy-nominated actress for her role in Showtime's and a Tony winner for her Broadway work in , infuses Gina with versatile energy, blending humor and pathos to depict her evolution from a chaotic party girl to a more responsible figure running a in season 2. Kether Donohue portrays Gabby, Gina's loyal and free-spirited best friend who works as a nurse's aide at the Valley Hills facility, providing and support in Gina's chaotic life. Donohue, known for her starring role as in FX's , brings a vivacious and unfiltered energy to Gabby, enhancing the show's exploration of and personal growth. Sara Rue stars as Julia Dunbar, Drew's ex-wife and a successful businesswoman navigating co-parenting their daughter while dealing with the aftermath of their divorce. Rue, recognized for roles in CBS's Mom and ABC's , delivers a nuanced performance that highlights Julia's strength and lingering emotional ties to Drew. Izzy G. plays Maddie Dunbar, Drew and Julia's wise-beyond-her-years teenage daughter who often acts as the mediator in her parents' post-divorce dynamics and grapples with her own adolescent challenges. Izzy G., previously seen in Netflix's , portrays Maddie with authenticity, contributing to storylines on family reconciliation and youth perspectives on adult issues. Linda Lavin plays Norma Goldman, a witty and no-nonsense resident at the Valley Hills assisted living facility who forms a close bond with Drew and Gina, offering sage advice and comic relief through her sharp observations. Promoted to series regular ahead of season 2, Lavin draws on her iconic portrayal of diner waitress Alice Hyatt in the long-running CBS sitcom Alice, where she earned multiple Emmy nominations, to deliver Norma's feisty, maternal presence that anchors the ensemble's interpersonal humor. The series' core dynamics revolve around the unlikely friendship between Drew and Gina, which begins as a pragmatic medical transaction but deepens into mutual support, challenging Drew's reserved nature and Gina's impulsiveness while fostering growth for both. This central relationship extends to the supporting mains, including the group and residents like Norma, creating a found that explores themes of , , and community amid illness.

Recurring and guest cast

The recurring cast of B Positive featured actors who portrayed key supporting characters, enriching the series' portrayal of family tensions, medical challenges, and communal bonds in the nursing home setting. These roles often highlighted interpersonal dynamics and provided comic relief or emotional depth without overshadowing the leads.
ActorCharacterDescriptionEpisodes (approx.)Source
Darryl StephensGideonGina's brother, whose presence explored sibling relationships and cultural family expectations.34https://deadline.com/2020/10/b-positive-izzy-g-cast-series-regular-briga-heelan-linda-lavin-among-5-recurring-cbs-comedy-series-chuck-lorre-1234596133/
David Anthony HigginsJerryA wisecracking dialysis patient at the clinic, enhancing the ensemble humor and camaraderie among patients.18https://www.imdb.com/title/tt11839500/fullcredits/
Jane SeymourBetteA glamorous nursing home resident and potential romantic interest for Drew in season 2, bringing elegance and wit to the facility's social dynamics.14https://www.imdb.com/title/tt11839500/
Briga HeelanSamantha TurnerAn uptight, intense millennial in Drew's dialysis group who does not suffer fools, adding layers to the support network around chronic illness.14https://deadline.com/2020/10/b-positive-izzy-g-cast-series-regular-briga-heelan-linda-lavin-among-5-recurring-cbs-comedy-series-chuck-lorre-1234596133/
Notable guest stars included as Peter, a charismatic former actor and resident whose episodes in season 2 highlighted and showbiz , deepening the community's intergenerational bonds. Hector Elizondo appeared as Shmuly, the 's , contributing to storylines on and loss. Other guests, such as as Gina's mother Lorraine, added familial conflict in specific episodes focused on heritage and reconciliation. These one-off appearances, often featuring medical professionals or , propelled plot developments like transplant anxieties or holiday gatherings, while emphasizing the series' themes of and .

Episodes

Series overview

B Positive is an sitcom that aired for two s on , comprising a total of 34 s: 18 in the first and 16 in the second. The series premiered on November 5, 2020, with its pilot , and the first concluded on May 13, 2021. The second began on October 14, 2021, and ended with the series finale on March 10, 2022. The narrative arc of B Positive centers on the evolving relationship between protagonists Drew Dunbar, a in need of a transplant, and Gina Dabrowski, his unexpected donor. Season 1 primarily explores the challenges of Drew's pre-transplant life on , his interactions at the dialysis center, culminating in the transplant from Gina, highlighting themes of , , and personal growth. In contrast, Season 2 shifts focus to post-surgery independence, with Gina taking ownership of a and navigating new business and romantic challenges, while Drew embarks on road trips, develops fresh relationships, and confronts life changes beyond his health crisis. The series concluded after two seasons when CBS decided not to renew it for a third, despite the season 2 finale featuring unresolved storylines that suggested potential for further exploration, as intended by creator .

Season 1 (2020–21)

The first season of B Positive premiered on on November 5, 2020, and concluded on May 13, 2021, consisting of 18 episodes that establish the core dynamics between Drew Dunbar and his donor Gina Dabrowski as they navigate personal crises and an unlikely . Throughout the season, Drew and Gina's relationship evolves from a transactional donor-recipient to a deeper bond, marked by , shared vulnerabilities during Drew's treatments, and mutual support amid their respective life upheavals. The where Gina works introduces an ensemble of colorful residents and staff, including the optimistic , the sharp-tongued Norma, and the anxious , who provide and emotional depth to the group's interactions. Drew's ongoing from his ex-wife Julia complicates his of daughter Maddie and his emotional recovery, often intersecting with Gina's chaotic past involving and financial instability. Key developments in the season highlight the characters' growth: early episodes focus on the initial donor matching and living arrangements, mid-season arcs explore the group's camaraderie and individual backstories, and later episodes build toward the pivotal transplant while addressing romantic entanglements and self-discovery. A significant milestone spans episodes 9 and 10: in "B Negative," receives a call about an available , and in "B Negative Part 2," the transplant ultimately fails, prompting Drew and Gina to reassess their own futures and strengthening their resolve. The season also features holiday-themed episodes, such as the installment in episode 5, "High Risk Factor," where tensions and festive mishaps underscore themes of belonging. Another arc milestone is Gina's in episode 11, "Recessive Gina," to uncover her , revealing insights into her heritage and resilience. The transplant for Drew and Gina is delayed until the finale, "," symbolizing the season's culmination of anticipation and hope. Production of the season was notably affected by the COVID-19 pandemic, with filming for episodes 6 onward resuming under strict safety protocols after an initial pilot completed pre-shutdown. A mid-season hiatus extended from late December 2020 through mid-January 2021 due to a surge in COVID-19 cases in Los Angeles, delaying production on Warner Bros. Television shows including B Positive and contributing to a compressed backorder schedule for the remaining episodes. This pause followed the airing of episode 5 on December 17, 2020, resulting in a seven-week gap before episode 6 aired on January 21, 2021. The season's episodes are summarized in the following table:
No.TitleAir DateSynopsis
1PilotNovember 5, 2020Drew, a recently , discovers he needs a and finds his donor in an unexpected person.
2Die AlysisNovember 12, 2020Drew’s worsening condition prompts him to ensure Gina’s commitment to donating her , offering her something she can’t refuse.
3Foreign BodiesNovember 19, 2020Gina settles into Drew’s house, causing him to question his decision.
4Joint December 3, 2020After a tough , Gina surprises Drew to lift his spirits.
5High Risk FactorDecember 17, 2020Drew tracks Gina’s reckless behavior with an app due to concern.
6Open Heart January 21, 2021Gina manages a evaluation while coping with an ex’s news.
7February 11, 2021Missing a soccer game due to , Drew questions his sacrifices.
8Integration TherapyFebruary 18, 2021Drew realizes he lost post-; Gina hosts a group party.
9B NegativeFebruary 25, 2021 receives a call about an available , prompting Drew and Gina to think about their futures.
10B Negative Part 2March 4, 2021Drew’s after a friend’s failed is eased by Gina.
11Recessive GinaMarch 11, 2021Gina takes Drew and Norma on a for her ’s medical records.
12Canine ExtractionApril 1, 2021Gina trains a ; Drew deals with Maddie growing up.
13Inflammatory ResponseApril 8, 2021Norma moves into Drew’s house after a fire; Gina and ’s romance grows.
14Love April 15, 2021Gina sabotages her relationship with over a Vegas invite.
15Miss DiagnosisApril 22, 2021Drew goes on a first post- date; Gina helps with an .
16A Cute AsphyxiationApril 29, 2021Drew and Gina struggle in new relationships; Norma plans an trip with Gina.
17TransplanticipationMay 6, 2021Gina and Drew plan their futures with scheduled.
18May 13, 2021Pre-, Gina seeks a new ; Drew celebrates his last day.

Season 2 (2021–22)

The second season of B Positive premiered on October 14, 2021, and concluded on March 10, 2022, consisting of 16 episodes that shifted focus to the characters' post-transplant lives, emphasizing , new relationships, and within the . Building on the transplant from the first season, the narrative arcs explored Drew Dunbar's () evolving therapy practice and romantic entanglements, including a brief fling and a cross-country that prompted self-reflection, while Gina Dabrowski () navigated her empowerment as the new owner of Valley Hills, tackling business challenges, family dynamics with her sister Natalie, and entrepreneurial ventures like managing the facility's staff and . The ensemble expanded with deeper backstories, such as Norma's family tensions and Jerry's health improvements, incorporating humor centered on the absurdities of aging and , alongside appearances that provided emotional closure, such as those aiding in a beloved . Key events highlighted Gina's trials, including mediating resident disputes and fending off rival facilities, contrasted with Drew's and budding connections that ultimately drew him back to the community. The season culminated in character resolutions, with Gina weighing a sale of Valley Hills and Drew preparing for an adventure, underscoring themes of found family and forward momentum. Increased comedic elements arose from recovery mishaps, like pet integrations and road trip breakdowns, blending lighthearted moments with poignant reflections on loss and change. The following table lists the season's episodes, including titles, original air dates on CBS, and brief plot synopses:
No. overallNo. in seasonTitleAir dateSynopsis
191Love, Taxes and a KidneyOctober 14, 2021As Gina and Drew adjust to life after the kidney transplant surgery, Drew develops romantic feelings for a new person, while Gina receives surprising news about a friend's death.
202Vermont, Switzerland and ConnecticutOctober 21, 2021Gina's newfound wealth from an inheritance strains her relationship with Eli; meanwhile, Drew's girlfriend Adriana makes an unexpected visit.
213Bagels, Billiards and a Magic ShowOctober 28, 2021On her first day as owner of Valley Hills, Gina enlists Drew's help to connect with a short-tempered resident whose wife is ill.
224Baseball, Walkers and WineNovember 4, 2021Gina devises a plan to give resident Meredith space from her overprotective husband; Drew musters the courage to confess his feelings to Gina.
235Novocaine, Bond and BocceNovember 11, 2021Gina urges Jerry to relocate to the senior center after he faints at work; Drew and Gina confront the aftermath of a drunken night together.
246A Dishwasher, a Fire and a Remote ControlNovember 18, 2021Gina faces pressure to dismiss the facility's chef; Drew loses patience with a challenging therapy patient.
257A Camper, a Compass and a CannoliDecember 2, 2021Gina introduces her dog Cannoli to Valley Hills, where it bonds with the seniors; Drew gears up for a cross-country journey in a camper van.
268A Dog, a Mousse and a BatDecember 9, 2021Gina assists Harry in preparing a special anniversary dinner for his ailing wife; on the road, Drew encounters a charming young woman.
279Heartburn, Woodstock and RibsJanuary 6, 2022Drew returns from his trip to join Gina and the Valley Hills community in grieving the loss of a dear friend.
2810S'mores, Elvis and a CubanoJanuary 13, 2022Gina's sister Natalie pays a surprise visit; Drew and Harry embark on a road trip, though their destinations differ.
2911Louisville, Bubbaroo and SullyJanuary 20, 2022Gina employs Peter's son as her lawyer, complicating matters when he asks her on a date; Drew and Harry's van fails during their journey, stranding them.
3012Dagobah, a Room and a Chimney SweepJanuary 27, 2022Valley Hills residents vie for an upgraded room; Drew and Harry arrive at the Grand Tetons, but Drew lacks the anticipated revelation.
3113A Boss, a Bear Claw and a DefibrillatorFebruary 3, 2022Gina grapples with her dual role as boss and friend to Gabby and Gideon; Drew takes on driving the Valley Hills van; Jerry discovers he is fit to depart the facility.
3214Osteoporosis, Benihana and a SlinkyFebruary 24, 2022Gina intervenes in the conflict between Norma and her abrasive sister Irene at Valley Hills; Harry arranges a date for Drew; Spencer and Bette advance their relationship.
3315Payroll, a Waterwall and Valley ForgeMarch 3, 2022After Mrs. Ludlum resigns and joins a competing facility, Gina fights to maintain operations at Valley Hills; Drew debates another road trip versus remaining near Gina.
3416Juneau, Froyo and Mario KartMarch 10, 2022Gina faces a dilemma with an offer to sell Valley Hills to a rival; Drew readies for his major expedition to Alaska.

Production

Development and conception

B Positive was conceived by writer and producer , who drew inspiration from his personal experience undergoing a kidney transplant in 2013 due to complications from . His donor was the daughter of his mother's , an unsolicited offer that highlighted the unexpected of living donations and profoundly impacted Pennette's perspective on the process. Pennette developed the series idea shortly after his surgery, aiming to transform his story into a that could raise awareness about while blending humor with heartfelt authenticity. Having previously collaborated with Chuck Lorre as a co-executive producer on the CBS sitcom Mom, Pennette brought the concept to Chuck Lorre Productions, where it was packaged as a multi-camera comedy produced by Warner Bros. Television. The creative vision focused on humanizing the often-overlooked aspects of organ donation, portraying donors as "true angels" and emphasizing the life-affirming bonds formed through the process, rather than sensationalizing medical elements for laughs. Initial script outlines prioritized real-life medical accuracy, such as the rigorous qualifications for living donors, to educate audiences without exaggeration, reflecting Pennette's commitment to respectful representation. CBS greenlit a pilot episode on January 23, 2020, marking one of the network's early commitments in the development cycle. The severely disrupted the 2020 pilot season, halting many productions, but B Positive stood out as one of the few completed pilots, facilitating its swift progression. On May 8, 2020, amid these delays, CBS issued a straight-to-series order for the show, allowing it to premiere later that year as a of continuity in broadcast television. Among the early challenges was adapting the gravity of real medical facts—such as the physical and emotional toll of transplantation—into a lighthearted format, a task Pennette described as "scary" due to the pressure to get it "perfect." Lorre's encouragement proved pivotal, prompting Pennette to complete the pilot script in just one week despite the emotional weight. The series title derives from the protagonist's B positive , essential for donor compatibility, and was adjusted from an initial of B Negative to better capture the optimistic viewpoint of the donor character and the overall theme of hope. In October 2021, Pennette stepped down as during Season 2 production.

Casting process

The casting process for B Positive began in early 2020, prior to the onset of the , with securing the role of Gina Dabrowski, a working-class woman living in her mother's basement who impulsively donates a to the protagonist. Shortly thereafter, on March 2, 2020, was cast as Gabby, Gina's party-loving best friend and co-worker at a , while joined as Julia Dunbar, the ex-wife of lead character Drew. The following day, was announced as Drew Dunbar, a newly divorced facing renal failure, completing the core ensemble for the pilot episode. Filming of the pilot wrapped in March 2020, making B Positive the only network comedy pilot to complete production before pandemic-related shutdowns halted most television work across the industry. As the series received a series order in May 2020 and prepared for full production amid restrictions, subsequent casting adapted to the challenges of the crisis, including likely reliance on virtual auditions and self-tapes, which became standard for ongoing hires in the entertainment sector during lockdowns. In August 2020, young actress Maggie Elizabeth Jones was cast in a recasting of one of Drew's children, reflecting adjustments to fit the evolving family dynamic in the series. On October 12, 2020, Izzy G. was cast in a second recasting as Maddie Dunbar, Drew's daughter, and promoted to series regular. Additional supporting roles were filled iteratively as production ramped up in late 2020. In October 2020, veteran actress Linda Lavin was brought on as a recurring guest in the role of Norma, a senior resident at the nursing home, alongside other recurring additions such as Briga Heelan, Darryl Stephens, and Bernie Kopell to deepen the ensemble's portrayal of interpersonal relationships. The process emphasized authentic representation of working-class and diverse backgrounds, evident in Gina's characterization and the inclusion of actors like Stephens as Gideon, a nurse at Valley Hills, contributing to the show's focus on multifaceted, everyday characters. For Season 2, several recurring performers, including Lavin, were elevated to series regulars, while new guests were selected based on availability to support story arcs involving extended family and community ties.

Filming and locations

B Positive was primarily filmed at in , where the production utilized soundstages to construct key interiors such as the hospital, , and apartment sets. This studio-based approach allowed for efficient multi-camera filming, aligning with the show's format as a traditional . Season 1 production occurred amid the , with filming resuming in late summer after the pilot was completed pre-shutdown; the team followed rigorous safety protocols, including regular testing, masking, and reduced crew sizes to mitigate health risks. The shooting schedule adhered to the standard multi-camera rhythm of five to six days per week, enabling a full 18-episode order despite intermittent pauses due to rising cases in . The series employed a three-camera rig for its multi-camera setup, capturing scenes in real time to preserve the comedic timing essential to the genre. The pilot was shot before a live studio audience. Due to the COVID-19 pandemic, subsequent episodes were filmed without a live audience, relying on pre-recorded laughter to maintain the sitcom's energy. Exterior shots, including those evoking the setting, were occasionally filmed on location around the Burbank area for realism, while focused on refining dialogue and visuals to ensure narrative flow. Specific efforts in addressed procedural elements for plausibility, drawing on input during assembly.

Broadcast and reception

Airing and distribution

B Positive premiered on in the United States on November 5, 2020, airing on nights initially in the 8:30 p.m. ET/PT time slot. In March 2021, the series shifted to the 9:30 p.m. slot following a schedule adjustment to accommodate another comedy. It concluded its run on March 10, 2022, after two seasons. During its broadcast, episodes were simultaneously available for streaming on in the , which rebranded as Paramount+ on March 4, 2021. The series, produced by Warner Bros. Television, was subject to limited streaming rights on the platform, with availability restricted to the current season at a time. Internationally, B Positive was distributed in by , premiering on CTV on November 5, 2020, alongside its debut. It was available on Paramount+ in select global markets during its run, though distribution varied by region due to licensing. Following the series' cancellation in May 2022, B Positive was removed from Paramount+ in the as licensing for content expired post-run. As of November 2025, it is no longer offered on subscription streaming services in the but can be rented or purchased digitally on Amazon Video, Apple TV, and Fandango at Home. No physical home media releases, such as DVD or Blu-ray, have been issued.

Critical response

B Positive received generally positive reviews from critics, particularly for its heartfelt exploration of organ donation and the strong performances of its leads, earning a Tomatometer score of 85% on Rotten Tomatoes across its run. Season 1 garnered an 85% approval rating based on 20 reviews, praised for its warm pilot and authentic depiction of kidney transplant challenges, drawn from creator Marco Pennette's personal experience. Season 2 has no Tomatometer score due to insufficient critic reviews, though it holds a 50% audience score. Critics lauded the show's portrayal of the process as grounded and empathetic, avoiding while addressing real medical and emotional realities. The chemistry between Thomas Middleditch's neurotic therapist Drew and Annaleigh Ashford's vibrant Gina was a standout, with Ashford's breakout performance earning particular acclaim for blending humor and vulnerability. Supporting cast members, including as Drew's mother Norma, were highlighted for their sharp comedic timing, adding depth to ensemble scenes at the facility. However, reviewers noted criticisms of formulaic sitcom tropes, such as the "odd couple" dynamic and recurring Chuck Lorre-style humor involving and family dysfunction, which occasionally felt predictable. Season 2 faced backlash for an uneven tone after overhauling the premise to center on Gina's life post-transplant, with some episodes perceived as preachy in tackling social issues like aging and healthcare access. Variety's 2020 review praised the pilot's warmth and potential for heartfelt comedy, while later assessments, including from in 2022 coverage of the show's changes, pointed to a perceived decline in narrative cohesion toward the end. The series received no major awards during its run.

Ratings and viewership

B Positive premiered to strong initial viewership, drawing 5.14 million viewers for its pilot episode on November 5, 2020, marking a solid start for the Chuck Lorre-produced on . The series maintained consistent audience interest throughout its first season, averaging 5.691 million viewers overall and achieving a 0.8 in the key 18-49 demographic according to Nielsen measurements. In its second season, viewership experienced a decline, averaging 4.56 million viewers, a drop attributed in part to time slot adjustments within CBS's Thursday comedy lineup that affected lead-in performance from shows like . The season finale on March 10, 2022, garnered 4.2 million viewers, reflecting ongoing challenges in retaining audience momentum amid competitive scheduling. Comparatively, B Positive underperformed relative to fellow Lorre productions such as , which averaged higher viewership in the 6-7 million range during overlapping seasons, falling short of network expectations for a multi-camera comedy in that lineup and contributing to its cancellation after two seasons. Post-broadcast streaming on Paramount+ provided a notable uplift, boosting total viewership by 20-30% through delayed and on-demand consumption in 2021-2022.

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