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Centruroides

Centruroides is a genus of scorpions in the family Buthidae, consisting of 102 species and known commonly as bark scorpions.^[1] First described by George Marx in 1890, the genus is characterized by slender bodies with thin pedipalps (pincers), a relatively thick metasoma (tail), and body lengths typically ranging from 5 to 10 cm.^[2]^[3] Species exhibit varied coloration from pale yellow or translucent to brown or black, and they fluoresce under ultraviolet light, a trait common to many scorpions.^[4] These scorpions are distributed across the Americas, with the highest diversity in Mexico (approximately 55 species), extending from the southwestern United States (five species) through Central America, the Caribbean, and into northern South America.^[1]^[5] They primarily inhabit arid and semi-arid environments but can adapt to subtropical and tropical regions, often seeking shelter under tree bark, in rock crevices, burrows, or debris piles during the day.^[3]^[4] Nocturnal and adept climbers, Centruroides species frequently enter human structures, making them common in urban and rural settings within their range.^[3] Medically, the genus is significant due to the neurotoxic venom produced by many species, which can cause intense pain, muscle spasms, and in severe cases, respiratory distress or death, especially in vulnerable populations like children and the elderly.^[1] Over 24 species in Mexico alone are considered hazardous to humans, with notable examples including Centruroides sculpturatus (also known as C. exilicauda in some regions; Arizona bark scorpion) and C. limpidus.^[1]^[3] Antivenoms, such as Anascorp®, are available for treating envenomations from key species, reflecting ongoing research into their venom components for both therapeutic and ecological insights.^[4]

Taxonomy

Etymology and History

The genus Centruroides was established by George Marx in 1890, with the name derived from the Greek words kéntron (sting), oúrá (tail), and the suffix -oidḗs (resembling), highlighting the characteristic elongated metasoma ending in a prominent vesicle and aculeus used for venom delivery. Species now assigned to Centruroides were initially described by Carl Ludwig Koch in 1837 within broader classifications of buthid scorpions, including placements under genera like Centrurus or Buthus. Subsequent key contributions came from Tamerlan Thorell in 1876, who described several Neotropical species later transferred to the genus, and Karl Friedrich Kraepelin in 1899, whose comprehensive revision of scorpions synthesized early taxonomy and outlined an initial roster of about 20 species for Centruroides. A major milestone occurred in the 20th century with Carlos Hoffmann's 1931 monograph on Mexican scorpions, which provided detailed revisions of regional Centruroides diversity and clarified distributions for over a dozen species in Mexico. Post-2000, the application of molecular phylogenetic tools has accelerated taxonomic progress, leading to a surge in new species descriptions, with more than 20 recognized since 2010 through integrative approaches combining morphology, DNA sequencing, and biogeography. As of 2025, the genus comprises 102 recognized species.^[1]

Classification and Phylogeny

The genus Centruroides Marx, 1890, is classified within the order Scorpiones Cuvier, 1812, the family Buthidae C.L. Koch, 1837, and the subfamily Centruroidinae Kraus, 1955. This placement reflects its affiliation with the diverse buthid scorpions, which are predominantly tropical and subtropical in distribution. Within the New World Buthidae, Centruroides forms a monophyletic group, distinguished by shared derived traits such as specific trichobothrial arrangements and metasomal segment morphology.^[6]^[7] Phylogenetically, Centruroides occupies a basal position relative to other American Buthidae, with molecular analyses indicating an early divergence of the subfamily Centruroidinae during the late Oligocene, approximately 28–35 million years ago. This timeline is supported by fossil-calibrated phylogenies using mitochondrial and nuclear markers, including 18S rRNA and cytochrome c oxidase subunit I (COI) genes, which highlight the genus's ancient origins in the Americas. Key internal clades, such as the arboreal "thorellii" group distributed across Neotropical regions like Mexico, Central America, and parts of South America, underscore regional diversification patterns within the genus.^[6]^[7]^[8]^[9] Subdivision of Centruroides into informal species groups relies on morphological features, particularly patterns of trichobothria (sensory setae) on the pedipalps and carapace, as well as chelal (pedipalp hand) proportions and dentition. Recent systematic revisions have reinforced the monophyly of the genus through integrated analyses of 90 morphological characters alongside multilocus DNA sequences from 12S rDNA, 16S rDNA, cytochrome c oxidase subunit I (COI), 18S rDNA, and 28S rDNA, resolving relationships among 102 taxa and confirming robust support for major lineages.^[6]

Physical Description

General Morphology

Centruroides scorpions exhibit a characteristically slender body structure adapted to their often arboreal lifestyle, consisting of a narrow prosoma and mesosoma, followed by an elongated metasoma comprising five distinct segments and terminating in a narrow telson. Total body length typically ranges from 40 to 100 mm in adults, enabling maneuverability in bark crevices and tree bark environments.^[5] Their light coloration, ranging from yellowish to brownish hues often accented with longitudinal stripes or mottling, provides effective camouflage against tree bark and rocky substrates, reducing visibility to predators and prey; species also fluoresce under ultraviolet light.^[4]^[3] Key anatomical features include large, well-developed pectines located ventrally on the mesosoma, which serve as chemosensory organs for detecting pheromones, prey scents, and substrate vibrations through numerous teeth and sensory pegs.^[5] The pedipalps are prominent, with slender chelae featuring fixed finger trichobothria arranged in type C pattern, aiding in tactile and airflow sensing during prey capture. Chelicerae are relatively small and simple, primarily used for feeding rather than defense, while the four pairs of walking legs are equipped with tarsal claws and sensory setae for adhesion during climbing. The ocular arrangement consists of a pair of median eyes and three pairs of lateral eyes on the prosoma, providing limited visual acuity but supplemented by other sensory modalities.^[10] Adaptations for both arboreal and terrestrial existence are evident in the flexible, elongated metasoma, which allows precise positioning of the telson for stinging while navigating uneven surfaces, and in the reduced granulation on the carapace and tergites compared to more heavily armored Buthidae genera, facilitating smoother movement and less abrasion on bark.^[3]

Sexual Dimorphism

Sexual dimorphism in Centruroides is marked by distinct morphological adaptations that reflect sex-specific reproductive demands, with males optimized for mate location and locomotion, and females for gestation and stability. Males exhibit a longer and thinner metasoma compared to females, often up to 23% longer in species such as C. margaritatus, where average male metasoma length measures 54.39 mm versus 44.25 mm in females.^[11] This elongation, coupled with a narrower mesosoma, reduces overall body mass and enhances agility during mate-searching.^[12] In C. margaritatus, metasoma length displays positive allometric scaling in males (slope >1 relative to carapace area), indicating disproportionate growth with body size that amplifies this dimorphism.^[11] Males also possess elongated pectines and legs, which aid in sensory detection and rapid movement across substrates. Pectine length shows slight male bias (7.70 mm vs. 7.38 mm in C. margaritatus), with negative allometry in males suggesting functional specialization for chemosensory roles in courtship.^[11] Leg length is significantly greater in males relative to body size (p < 0.0001), as seen in C. vittatus, where this contributes to sprint speeds 27% faster than in females (22.4 cm/s vs. 17.6 cm/s), supporting evasion and dispersal for reproduction.^[12] The telson bulb is larger in males, potentially linked to courtship displays.^[13] In contrast, females have a broader, more robust mesosoma to accommodate embryonic development, resulting in greater overall body mass and slower locomotion.^[12] Their metasoma is shorter and wider, with legs reduced in length, prioritizing stability over speed.^[13] The genital operculum is more pronounced in females, lacking the papillae present in males and appearing wider to facilitate oviposition.^[14] These traits underscore adaptive trade-offs, with female-biased size dimorphism in body mass (females larger by ~11% in carapace area in C. margaritatus) supporting reproductive investment.^[11]

Distribution and Habitat

Geographic Range

The genus Centruroides is native to the Americas, with a distribution that extends continuously from the southwestern United States—specifically Arizona and Texas—southward through Mexico and Central America, reaching northern South America in regions including Colombia and Venezuela. This range excludes southern portions of the continent, such as Chile and Argentina, where no native populations are recorded.^[7]^[15] Mexico represents the epicenter of diversity for Centruroides, with approximately 55 species documented across its territory as of 2025, far surpassing concentrations in other areas of the range.^[1] Introduced populations have expanded the genus's footprint beyond its native limits, notably in Florida, United States, and several Caribbean islands, facilitated by human activities such as international trade and shipping.^[16]^[4]^[17] Fossil evidence underscores the long-standing presence of Centruroides in Mexico, with the earliest known specimens—a juvenile buthid scorpion—preserved in amber from Chiapas and dated to the lower Miocene to upper Oligocene, approximately 23 to 28 million years ago. This paleontological record supports inferences of an ancient origin and stability in the region's scorpion fauna.^[18]

Habitat Preferences

Species of the genus Centruroides inhabit a wide range of macrohabitats across the Americas, from arid and semidesert regions to tropical rainforests and dry forests.^[19] They are commonly associated with dry, rocky environments but demonstrate tolerance for more humid zones, occurring at elevations from sea level up to approximately 2340 meters.^[20] For instance, Centruroides vittatus is prevalent in grasslands and deserts of the southwestern United States and northern Mexico, while species like Centruroides margaritatus thrive in the tropical dry forests of Central America.^[21] Microhabitat preferences within these environments emphasize sheltered, elevated refuges that provide protection and foraging opportunities. Centruroides species frequently occupy crevices under loose bark, rock fissures, leaf litter, and tree hollows, with many exhibiting semi-arboreal behaviors by climbing vegetation such as shrubs, cacti, and trees.^[4] Observations indicate that approximately 54% of encounters occur on vegetation, including stems, leaves, and trunks of plants like blackbrush (Acacia rigidula) and prickly pear (Opuntia engelmannii), where they seek refuge during the day and hunt at night.^[22] These scorpions also adapt to urban settings, invading homes, debris piles, and structures in human-altered landscapes.^[23] Abiotic tolerances of Centruroides species are adapted to warm, low-humidity conditions typical of their preferred habitats, with optimal activity temperatures ranging from 25–35°C.^[22] They exhibit low evaporative water loss through a waterproofed cuticle and derive moisture primarily from prey fluids, enabling survival in arid microenvironments while using refuges to retain humidity.^[22] Temperature gradients influence microhabitat selection, with individuals favoring cooler, shaded vegetation or lower substrate areas during hotter periods to regulate body heat.^[24]

Behavior and Life Cycle

Daily and Seasonal Activity

Species of the genus Centruroides exhibit strictly nocturnal activity patterns, emerging from daytime refuges at dusk to engage in foraging and movement. These scorpions spend daylight hours sheltered in crevices, under bark, or within rock piles to avoid predation and extreme temperatures, behaviors consistent with their preferences for protected microhabitats. Activity typically begins around 1900 hours and peaks in the initial four hours post-dusk, between 1900 and 2300 hours, before tapering into lower levels from midnight to 0300 hours, after which individuals retreat to refuges by 0300 hours.^[25] Seasonal activity in Centruroides varies by geographic range and climate. In temperate zones of the southwestern United States, such as Arizona, populations maintain activity throughout much of the year but show reduced movement during the coolest winter months (November to February), when nighttime temperatures drop below approximately 21°C (70°F); individuals often aggregate in sheltered sites to minimize exposure. Breeding-related activity, including mating, occurs primarily in fall, spring, and early summer, aligning with warmer periods that support higher mobility. True diapause is rare, though northern populations exhibit lowered metabolic rates and inactivity during prolonged cold spells.^[26]^[4]^[27] In tropical and subtropical regions, such as parts of Mexico and Central America, Centruroides species display elevated activity during wet seasons, driven by increased invertebrate prey abundance and favorable humidity levels that reduce desiccation risk. For example, in Mexico, scorpions are reported to be most abundant during the early rainy season (June–August).^[28] Temperature remains a key influencer across ranges, with immobility or minimal activity observed below 15–21°C, limiting surface foraging in cooler conditions. Moonlight effects are inconsistent; while some buthid scorpions reduce activity on full moon nights to avoid visual predators, studies on C. vittatus indicate no significant impact on microhabitat selection or movement.^[29]^[20]

Diet and Predation

_Centruroides scorpions are carnivorous predators with a diet consisting primarily of invertebrates, including insects such as crickets, cockroaches, beetles, flies, termites, and caterpillars, as well as arachnids like spiders and smaller conspecifics through opportunistic cannibalism.^[30]^[31] Centipedes are also consumed occasionally, while vertebrate prey is rare.^[30] Gut content analyses and observational studies confirm that insects form the bulk of their prey, with examples including small flies and termites as primary components in some populations.^[31] Cannibalism occurs, particularly among adults in high-density conditions, though specific frequencies vary by species and habitat.^[30] These scorpions employ a combination of ambush and active foraging strategies, often waiting motionless on vegetation or the ground before using their pedipalps to grasp passing prey and injecting venom to immobilize it.^[32] Foraging activity peaks nocturnally, with individuals climbing plants like legumes to access caterpillars, reducing interference while feeding.^[24] Their low metabolic rate—less than 24% of typical arthropod levels at 25°C—allows them to survive extended fasting periods of several months without compromising survival.^[33] Centruroides species face predation from birds such as owls, mammals including grasshopper mice, bats, and shrews, reptiles like lizards, and other arthropods such as tarantulas and centipedes.^[34]^[35] In response, they deploy defenses including stinging with their tail, thanatosis (feigning death), and rapid escape via climbing vegetation or fleeing to crevices.^[36]^[37]^[38] These behaviors are particularly effective against larger predators, with climbing providing elevation to evade ground-based threats.^[39]

Reproduction and Development

Centruroides scorpions display promiscuous mating, with individuals capable of multiple matings across their lifetime. The process involves an elaborate courtship where the male locates a receptive female, often using pheromones and substrate vibrations, before grasping her pedipalps to initiate a synchronized "promenade à deux" dance. During this display, the male may tap or judder the substrate with his body to signal, leading the pair over a deposited spermatophore for 5-20 minutes until the female retrieves the sperm packet with her gonopore.^[40]^[41] Post-mating, females occasionally cannibalize males, particularly smaller ones, though this behavior is infrequent and size-dependent rather than routine.^[42] These scorpions are viviparous, retaining embryos internally for nourishment before giving live birth. Gestation lasts 3-12 months, varying by species, temperature, and nutrition—for instance, approximately 8 months in C. vittatus and 3-4 months in C. bicolor. Females typically produce litters of 15-40 pale, translucent neonates measuring 3-5 mm in length, though sizes range from 24 in C. ochraceus to 26-46 in C. gracilis.^[27]^[43]^[30] Neonates emerge fully formed as first-instar scorplings and immediately climb onto the mother's back for protection, remaining there for 1-2 weeks until their first molt into the second instar, during which time she provides passive care by carrying them and abstaining from feeding to avoid accidental predation on her offspring. After dispersing, the young undergo 5-7 additional molts over 6-18 months to reach sexual maturity, with total development time around 12 months in species like C. ochraceus. Adults have a lifespan of 3-7 years in natural habitats, influenced by predation and environmental factors.^[4]^[30]^[43]

Venom and Interactions with Humans

Venom Properties

The venom of scorpions in the genus Centruroides is a complex mixture comprising 100-200 distinct components, predominantly short-chain peptides with molecular weights below 10 kDa.^[44]^[45] These include primarily neurotoxic peptides that target voltage-gated sodium (Na⁺) and potassium (K⁺) ion channels, such as the Css family of toxins isolated from C. sculpturatus, which consist of 60-76 amino acid residues stabilized by four disulfide bridges.^[46]^[47] Additionally, the venom contains enzymatic components like hyaluronidases, which facilitate toxin dispersal by degrading extracellular matrix, and serine proteases, which contribute to tissue disruption and inflammation.^[48]^[49] The primary mechanism of action involves neurotoxins that modulate ion channel function to induce neuromuscular dysfunction. Alpha-toxins, such as those in the CsE series from C. sculpturatus, bind to site 3 on voltage-gated Na⁺ channels, prolonging their open state and inhibiting inactivation, which leads to repetitive neuronal firing and hyperexcitability.^[46]^[50] In contrast, beta-toxins shift the voltage-dependent activation threshold of Na⁺ channels toward more negative potentials, promoting premature channel opening at resting potentials.^[51] K⁺ channel toxins, including alpha-KTx peptides, block outward K⁺ currents, further disrupting membrane repolarization.^[48] Venom potency varies across species, with median lethal doses (LD₅₀) in mice ranging from 0.25 to 1.5 mg/kg subcutaneously, reflecting differences in toxin abundance and specificity.^[52]^[53] From an evolutionary perspective, venom complexity in Centruroides is elevated in medically significant species like C. noxius and C. sculpturatus, where transcriptomic analyses reveal greater diversity in neurotoxic peptides adapted for mammalian targets compared to less potent congeners.^[54]^[55] This diversification likely arose through gene duplication and selection pressures favoring potent immobilization of vertebrate prey and defense.^[56] The venom glands, paired structures in the telson, produce approximately 0.1-0.5 µl of venom per sting, enabling efficient delivery despite the small volume.^[57]^[58]

Medical Significance

Envenomations by Centruroides scorpions represent a major public health concern in regions where these species are prevalent, particularly in Mexico and the southwestern United States. In Mexico, approximately 300,000 scorpion stings are treated annually, with Centruroides species responsible for the majority of medically significant cases. As of 2023, annual stings in Mexico remain stable at 200,000–300,000, with fatality rates below 1%, including 0% in localized outbreaks like Sinaloa.^[59]^[60] Fatalities remain rare, occurring at a rate of less than 1% overall, though severe morbidity is disproportionately high among children under 5 years old, who account for a significant portion of complications and deaths.^[61] In the United States, around 17,000 scorpion exposures were reported each year to poison control centers from 2005 to 2015, primarily involving C. sculpturatus in Arizona and surrounding states, with fatalities exceedingly uncommon—only four documented over an 11-year period from 2005 to 2015.^[62]^[61] Symptoms of Centruroides envenomation typically begin with local effects, including sharp pain and paresthesia at the sting site, often accompanied by minimal swelling.^[63] Systemic manifestations soon follow, featuring an autonomic storm with symptoms such as hypertension, profuse salivation, and diaphoresis, alongside neuromuscular excitation evidenced by involuntary muscle jerks, fasciculations, and restlessness.^[64] Additional signs may include nystagmus, hypersalivation, and tachycardia, reflecting the neurotoxic impact of the venom.^[64] Onset of these symptoms generally occurs within 5 to 30 minutes post-sting, reaching peak severity in 1 to 5 hours, with most resolving over 24 to 72 hours in uncomplicated cases.^[65] Certain populations face elevated risks from Centruroides stings due to physiological vulnerabilities. Children and elderly individuals are most affected, experiencing more intense systemic reactions and higher rates of complications owing to lower body mass and reduced physiological reserves.^[66]^[67] In Mexico, stings from highly toxic species like C. noxius contribute to the greatest lethality, particularly in endemic areas of the Pacific coast.^[68]

Treatment and Management

Immediate care for Centruroides envenomation focuses on supportive measures to alleviate symptoms and stabilize the patient. Application of ice packs to the sting site helps reduce local pain and swelling, while non-opioid analgesics such as ibuprofen are recommended for pain management; opioids should be avoided due to potential respiratory depression risks. Vital signs must be closely monitored for at least four hours, particularly in children who may develop severe symptoms rapidly, and tetanus prophylaxis is advised if needed. Supportive interventions include intravenous fluids to address dehydration from excessive salivation or sweating, along with oxygen supplementation or intubation for respiratory distress in severe cases.^[67]^[69] Antivenom therapy is indicated for moderate to severe envenomations characterized by neuromuscular or autonomic dysfunction. In the United States, Anascorp, an equine-derived F(ab')2 antivenom targeting Centruroides sculpturatus and cross-reactive with other North American species, is administered intravenously (typically three vials diluted in saline over 30 minutes); it rapidly reverses neurologic symptoms, with severe effects resolving in 15 to 30 minutes and mild-to-moderate symptoms in 45 to 90 minutes, achieving 95 to 100% relief of systemic signs within four hours. In Mexico, polyvalent antivenoms produced against venoms from species including the C. limpidus complex are standard, demonstrating high efficacy in neutralizing toxins and shortening symptom duration compared to supportive care alone. These antivenoms carry risks such as serum sickness (approximately 0.5% incidence), but anaphylaxis is rare with modern formulations.^[70]^[69]^[71]^[67] Prevention strategies emphasize reducing human-scorpion encounters in endemic regions. Habitat modification, such as sealing cracks and crevices in homes and removing rock piles or debris, minimizes scorpion entry, while ultraviolet (Wood's) lamps aid in detecting the fluorescent Centruroides species at night. Public health education campaigns in high-risk areas promote wearing protective footwear and shaking out clothing or bedding; no vaccine against scorpion envenomation is currently available.^[69]^[67]

Diversity and Conservation

Species Diversity

The genus Centruroides encompasses 102 valid species as of 2025, making it one of the most speciose genera within the family Buthidae.^[1] This diversity is unevenly distributed across the Neotropics and southern Nearctic, with Mexico harboring the highest number at 55 species, reflecting the region's varied ecosystems from arid deserts to humid forests.^[72] The genus's range extends from the southwestern United States through Central America to northern South America and the Caribbean, where species richness decreases southward.^[73] Taxonomic research continues to uncover new species, with at least 11 described since 2020 through integrated morphological and molecular approaches.^[74] ^[75] For instance, a 2021 revision of the arboreal "thorellii" clade identified six new species from Guatemala and Mexico using DNA barcoding of the COI gene alongside 112 morphological characters, tripling the known diversity in that lineage.^[74] Additional discoveries in 2025 include Centruroides lenca from Honduras and a new species from Oaxaca, Mexico, highlighting the role of targeted surveys in fragmented habitats.^[75] ^[76] These additions underscore the genus's dynamic taxonomy, driven by advances in phylogenetics that delineate previously overlooked forms.^[9] Intraspecific variation within Centruroides species is pronounced, often manifesting as clinal adaptations in coloration and body size that correspond to environmental gradients.^[8] Populations of C. exilicauda in Baja California, for example, show marked size differences between mainland and island forms, with island individuals smaller and more brightly colored, likely reflecting insular isolation and resource constraints.^[8] Similarly, C. vittatus displays multiple color morphs, from pale yellow to darker patterns, varying geographically and aiding crypsis in diverse substrates.^[77] Such phenotypic plasticity complicates morphological identification and emphasizes the need for integrative taxonomy. Cryptic diversity further enriches the genus, particularly in species complexes like limpidus, where genetic analyses have revealed hidden lineages indistinguishable by external morphology.^[78] The C. limpidus complex, distributed across central Mexico, includes subspecies such as C. l. tecomanus that molecular data suggest warrant full species status due to distinct phylogeographic breaks.^[78] Mitochondrial and nuclear markers have resolved these cryptic entities, demonstrating how gene flow barriers in heterogeneous landscapes promote speciation.^[79] Habitat loss from deforestation and urbanization threatens this diversity by fragmenting populations and inducing synonymies in taxonomic records, as isolated groups may appear morphologically similar despite genetic divergence.^[80] The IUCN Red List has assessed approximately 20% of Centruroides species, with many classified as vulnerable or near threatened due to such pressures, underscoring the urgency for conservation-focused taxonomy.^[81]

Notable Species

Centruroides sculpturatus, commonly known as the Arizona bark scorpion, is distributed across the southwestern United States, including Arizona, California, Nevada, New Mexico, and Utah, as well as northern Sonora in Mexico.^[82] This species is highly fluorescent under ultraviolet light, a trait shared with most scorpions due to compounds in their exoskeleton that cause a greenish glow, aiding in detection during nocturnal surveys.^[83] Its venom is potent, with an LD50 of approximately 1.15 mg/kg in mice, making it the most medically significant scorpion in the U.S.^[84] Centruroides vittatus, the striped bark scorpion, has a wide distribution in the southern United States from California to Florida and extends into northern Mexico, including states like Chihuahua, Coahuila, Nuevo León, and Tamaulipas.^[85] Adults measure 50-70 mm in length and are adaptable to urban environments, often found in buildings, under rocks, and in leaf litter.^[77] Its sting causes milder symptoms compared to other Centruroides species, typically resulting in localized pain, swelling, and redness without severe systemic effects in most cases.^[67] Centruroides noxius is endemic to Mexico, primarily along the Pacific coastal region in states such as Nayarit, Colima, and Jalisco.^[86] It possesses one of the most toxic venoms in the genus, with an LD50 of 0.26 mg/kg in mice, contributing significantly to severe envenomations in Mexico where it accounts for a substantial portion of medically important scorpion stings.^[61] Among other notable species, Centruroides gracilis, the Florida bark scorpion, inhabits tropical and subtropical regions of the Caribbean, Florida, and [Central America](/page/Central America), favoring arboreal habitats in humid forests where it climbs trees and vegetation.^[87] This species reaches lengths of up to 50 mm and has venom of moderate potency, with an LD50 of 2.7 mg/kg in mice, causing painful but generally non-life-threatening stings similar to a bee sting.^[17]

Conservation Status

The genus Centruroides encompasses over 100 species, the majority of which have not been formally assessed by the International Union for Conservation of Nature (IUCN) Red List, rendering approximately 85-90% of species effectively Data Deficient due to insufficient data on population sizes, trends, and threats.^[88] Among the few evaluated species, such as C. vittatus, no global special status is assigned, though regional assessments indicate vulnerability in isolated populations, like Endangered status in Illinois, USA, owing to habitat fragmentation.^[10] No Centruroides species is currently listed as Endangered or Critically Endangered on the IUCN Red List, but endemics in Mexico face escalating risks from urban expansion encroaching on arid and semi-arid habitats.^[89] Primary threats to Centruroides populations include habitat destruction, particularly deforestation and land conversion for agriculture and urbanization in Mexico, where tree cover has declined by about 10% since 2000, equivalent to 5.2 million hectares lost.^[90] Pesticide application in agricultural areas reduces invertebrate prey availability, indirectly pressuring scorpion populations that rely on insects and arachnids for sustenance.^[91] Additionally, collection for the international pet trade contributes to localized declines, with scorpions comprising a notable portion of the 350 arachnid species documented in global trade records, though overall imports have decreased by up to 55% in the past decade; in Mexico, tens of thousands of wild animals are harvested annually for commercial purposes, including exotic pets.^[92]^[93] Conservation efforts for Centruroides are integrated into broader biodiversity protections in Mexico, where scorpion diversity hotspots overlap with the national system of protected areas, including biosphere reserves that cover diverse ecosystems like those in Baja California Sur and Yucatán.^[91]^[94] These reserves, numbering 41 across the country, promote habitat preservation and sustainable land use while supporting research on species distributions and ecology to inform future assessments.^[95] Ongoing studies model potential distribution shifts under climate change scenarios, aiding targeted monitoring of vulnerable endemics.^[91] However, no Centruroides species is regulated under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES), limiting international controls on pet trade exports.

References

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Microhabitat preferences for the errant scorpion, Centruroides ...
Aug 7, 2025 · Vegetation as a preferred microhabitat for scorpions has rarely been considered despite many Buthidae (the bark scorpions) being ...
[24]
The effect of microhabitat use on the foraging and diet of ... - BioOne
Apr 12, 2022 · Centruroides vittatus is nocturnal, with refuges in debris, beneath vegetation, under bark, and in holes in the ground used during the day, but ...Missing: sources | Show results with:sources
[25]
(PDF) Activity Trends and Movement Distances in the Arizona Bark ...
Aug 9, 2025 · The bark scorpion, Centruroides sculpturatus Ewing, is a nocturnal, cryptic, nonburrowing, mobile species that is common in urban landscapes ...
[26]
[PDF] Scorpions in Arizona
Scorpions are nocturnal or diurnal, predatory animals that feed on a ... Despite their bad reputation, only one species in the western U.S. (the bark scorpion, ...Missing: patterns | Show results with:patterns
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Striped Bark Scorpion - Field Guide to Common Texas Insects
Mating apparently takes place in the fall, spring and early summer. All ... Centruroides are active foragers and do not burrow. They are considered ...
[28]
Scorpiones) in an area of Caatinga vegetation in northeastern Brazil
Aug 6, 2025 · The abundance of scorpions captured was significantly correlated with precipitation, real evapotranspiration, and abundance of invertebrates ( ...
[29]
Seasonal patterns of scorpion diversity along a gradient of aridity in ...
This study was carried out to assess seasonal changes of the scorpion biodiversity at the region of Tebessa (northeastern Algeria) along a climatic gradient.
[30]
[PDF] Notes on the diet and reproduction of the bark scorpion ...
Jul 16, 2020 · Opportunistic species, such as members of the genus Centruroides, commonly occupy unstable and disturbed environments, where they tend to ...<|separator|>
[31]
[PDF] Florida State University, Department of Biology
From this, prey DNA was amplified and analyzed to reveal the diet of the predator. Methods. •152 scorpions of the species C. hentzi were collected from.
[32]
Reproductive tradeoff limits the predatory efficiency of female ...
Sep 14, 2013 · We investigated potential tradeoffs that may occur between reproductive activities and feeding performance in female Arizona Bark Scorpions ( ...
[33]
Low Metabolic Rate in Scorpions: Implications for Population ...
Scorpions have a low metabolic rate, less than 24% of typical arthropods at 25°C, which may contribute to their high biomass and may favor cannibalism.ABSTRACT · Introduction · Materials and methods · Results
[34]
Scorpion Predators
Lizards, bats, grasshoppers and centipedes are another animals that represent a danger to some types of scorpions. Immunity, the grasshopper mouse. It turns out ...
[35]
[PDF] Predatory interactions between Centruroides scorpions and the ...
As soon as an encounter was finished, the tarantula was removed from the arena and starved again if it succeeded in catching and eating the prey. Otherwise ...
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A 'striking' relationship: scorpion defensive behaviour and its relation ...
Apr 3, 2017 · Like many other venomous organisms, scorpions use their venom in defence against predators. Scorpions apply their venomous stinger by ...
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Risk Assessment & Refuge Effects on Scorpion Defense Behaviors
Aug 20, 2020 · However, as the threat persisted, these spiders would begin to use other defensive behaviors such as thanatosis, longer bouts of fleeing, ...
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Oct 1, 2022 · In this species, thanatosis is one of the five defensive behaviors displayed when predator attacks were simulated, along with fleeing, stinging ...
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A Sting Operation: Risk Assessment and Venom Expenditure ... - NIH
We quantified antipredator behaviors of the clinically significant Arizona bark scorpion (Centruroides sculpturatus) in their natural environment.
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[PDF] Substrate vibrations in the scorpion Centruroides margaritatus ...
Nov 30, 2009 · It has been suggested that substrate vibrations are generated by juddering and that females respond to them by approaching the male, but its ...Missing: tapping | Show results with:tapping
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(PDF) The life history of Centruroides gracilis (Scorpiones, Buthidae)
Aug 7, 2025 · After giving live birth to anywhere between 26-46 offspring (Francke & Jones, 1982), the young of C. gracilis will seek refuge and protection on ...
[42]
Sexual cannibalism in scorpions: fact or fiction? - ScienceDirect.com
There is empirical support for the size-dependent sexual cannibalism predicted by mate choice through premating sexual cannibalism. ... Centruroides vittatus ( ...
[43]
Buthidae), with comments on parthenogenesis - ResearchGate
Dec 19, 2024 · development of the buthid scorpion Centruroides ochraceus (Pocock, 1898), species distributed in the Yucatan peninsula, Mexico. The results were ...
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Biochemical characterization of the venom from the Mexican ...
Jan 15, 2020 · The LD50 was determined for 13 different species of scorpions of the genus Centruroides of Mexico (Riaño-Umbarila et al., 2017). However, a more ...
[45]
Mass fingerprinting and electrophysiological analysis of the venom ...
Jul 3, 2018 · Two peptides were obtained in pure format and completely sequenced: one with 29 amino acids, showing sequence similarity to an “orphan peptide” ...Missing: count | Show results with:count
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Scorpion toxins specific for Na+‐channels - Possani - 1999
Dec 25, 2001 · Na+-channel specific scorpion toxins are peptides of 60–76 amino acid residues in length, tightly bound by four disulfide bridges.
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Purification and chemical and biological characterizations of seven ...
Apr 5, 2020 · S. A. Purification and Chemical and Biological Characterizations of Seven. Toxins from the Mexican Scorpion, Centruroides suffusus suffusus”.
[48]
Venom characterization of the bark scorpion Centruroides edwardsii ...
Dec 5, 2019 · Centruroides edwardsii venom contains a hyaluronidase, proteases, CRiSPs and several peptides that modulate Na + and K + channels.
[49]
SciELO Brasil - An overview of some enzymes from buthid scorpion ...
1 (identity of 100 %, Table 2), which is a hyaluronidase 1-like sequence from the venom of Centruroides sculpturatus, and to the protein WDU65909.1 a putative ...Missing: Css | Show results with:Css
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Alpha-toxin CsE5 - Centruroides sculpturatus (Arizona bark scorpion)
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal ...Missing: Css | Show results with:Css
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Toxin CsEv3 - Centruroides sculpturatus (Arizona bark scorpion)
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby ...Missing: Css | Show results with:Css
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Scorpions from Mexico: From Species Diversity to Venom Complexity
Among the Mexican scorpions, Centruroides noxius was found to contain the most potent venom against mammals. The LD50 of this venom is 5 µg per 20 g mouse ...
[53]
The Scorpion Files - Centruroides excilicauda (Buthidae) - NTNU
An LD50 value of 1,12 mg/kg is reported for this species, though this is known to vary greatly even within a close population (F. Russell, personal ...
[54]
Disparity among venom components, and morphometrics in ...
In Mexico, 22 medically important scorpion species have been documented within the genus Centruroides Marx 1890; González-Santillán and Possani (2018); García- ...
[55]
Scorpions from Mexico: From Species Diversity to Venom Complexity
Other dangerous species of Mexican scorpions studied were Centruroides sculpturatus [69,70,71], Centruroides limpidus [72,73,74], Centruroides infamatus [74].
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Insights into how development and life-history dynamics shape the ...
Jan 7, 2021 · In this review, we explore the current literature that is unraveling the temporal dynamics of the venom system that are required by these animals to meet their ...Missing: LD50 | Show results with:LD50
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Scorpion venom and its adaptive role against pathogens - Frontiers
This study investigated in the scorpion Centruroides granosus Thorell, 1876 (Scorpiones: Buthidae) whether the venom provided protection against the ...
[58]
GENUS CENTRUROIDES MARX*
The scorpion possesses two pyriform venom glands contained in the telson, a bulbous structure at the posterior end of the animal. Each gland discharges its ...<|separator|>
[59]
Factors involved in the resilience of incidence and decrease of ...
In instances of severe envenomation by Centruroides, timely administration of antivenom treatment is crucial, with reports noting cessation of most symptoms ( ...
[60]
Scorpion Envenomation: Background, Pathophysiology, Etiology
Oct 15, 2021 · Generally, most lethal scorpions have an LD50 below 1.5 mg/kg. The average yield per scorpion via electrical excitation of the venom gland for a ...
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Geographic Distribution of Scorpion Exposures in the United States ...
Over the past decade, nearly 17 000 scorpion exposures were reported annually to poison control centers (PCCs) throughout the United States.
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The stings usually cause only localized pain with minimal swelling, some lymphangitis with regional lymphadenopathy, increased skin temperature, and tenderness ...
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Scorpion Envenomation Clinical Presentation - Medscape Reference
Oct 15, 2021 · A person who has been stung by a scorpion usually has four signs, with the most common being mydriasis, nystagmus, hypersalivation, dysphagia, and restlessness.
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Aug 14, 2014 · In the United States, there were 18,261 reported cases of scorpion stings in 2013. Of these, 5,187 cases occurred in patients 19 years of age or ...
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Oct 3, 2023 · Scorpion stings are painful but rarely life-threatening. Young children and older adults are most at risk of serious complications.
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Scorpion Toxicity - StatPearls - NCBI Bookshelf - NIH
Although most scorpion stings are mild and not life-threatening, scorpion stings can cause significant harm to the patient, especially in very young or elderly ...
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(PDF) A new scorpion species of the genus Centruroides (Scorpiones
Aug 6, 2025 · Centruroides chamela sp. nov. from Chamela, Jalisco, Mexico is described. The new species is compared primarily with C. elegans Thorell, because both species ...
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Scorpion Envenomation Treatment & Management
Oct 15, 2021 · Treatment generally consists of moving the patient away from the scorpion and stabilizing the patient's airway and vital signs, followed by administration of ...
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[PDF] Anascorp® Centruroides (Scorpion) Immune F(ab')2 (Equine ... - FDA
Jul 27, 2011 · Initiate treatment with Anascorp as soon as possible after scorpion sting in patients who develop clinically important signs of scorpion.
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Management of scorpion envenoming: a systematic review and ...
Apr 8, 2017 · Antivenom against Centruroides sp. are effective in reversing the clinical syndrome faster than no antivenom treatment in children.
[71]
STATE OF THE ART ON THE DEVELOPMENT OF A ... - ScienceDirect
Mar 4, 2025 · ... genus Centruroides with 102 recorded species. This genus is home to the largest number of species dangerous to humans as described in Mexico ...<|separator|>
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North American scorpion species of public health importance with a ...
Centruroides comprises 21 dangerous scorpion species distributed in Mexico and southwestern USA. •. Mexico is considered a hotspot for scorpionism. •. Medically ...
[73]
"A new <i>Centruroides</i> species and first record of <i>C ...
A new species of striped bark scorpions, Centruroides lenca sp. n. is described, based on both sexes, from the Pacayita Volcano Biological Reserve.Missing: molecular tools
[74]
Buthidae) from the northern mountain range of Oaxaca, Mexico Una ...
Centruroides serrano sp. nov. from the Sierra Juárez of Oaxaca (Villa Alta District) is described. This is the eleventh species of the genus reported from ...
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The Scorpion Files - Centruroides vittatus (Buthidae) - NTNU
This species are known to have several color variations. The most common color variant of this species has the characteristic dark interocular triangle with ...
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A multigene approach to identify the scorpion species (Arachnida
Centruroides tecomanus is a species complex. Due to their morphological similarity with C. limpidus, C. tecomanus was described as C. limpidus tecomanus ...<|separator|>
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"Phylogenetic Structure of Two Central Mexican Centruroides ...
Several data sets (mitochondrial and nuclear genes, allozymes, morphology, toxin structure/activity, etc.) could be analyzed to establish the true taxonomic and ...
[78]
The scorpions of the Estación de Biología Chamela, Jalisco, Mexico ...
Jun 27, 2025 · Mexico possesses one of the most diverse scorpion faunas in the world with 38 genera, 313 species, and four subspecies, distributed across nine ...
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Centruroides vittatus | NatureServe Explorer
Nov 1, 2025 · Distributions of the scorpions Centruroides vittatus (Say) and Centruroides hentzi (Banks) in the United States and Mexico (Scorpiones ...
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[PDF] Arizona Bark Scorpion (Centruroides sculpturatus) - Lacounty
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Ultraviolet Scorpions - Ask A Biologist
All scorpions will fluoresce under a ultraviolet (UV) light, also known as a "blacklight". The glow is caused by an unidentified substance in a thin layer in ...
[82]
Full Neutralization of Centruroides sculpturatus Scorpion Venom by ...
Oct 6, 2021 · A combination of both scFvs at a molar ratio of 1:5:5 (toxins: scFv 10FG2: scFv LR) neutralized the venom without the appearance of any signs of intoxication.
[83]
[PDF] distributions of the scorpions centruroides
Centruroides vittatus occurs just across the latter watercourses in Holt County, Missouri, and Monroe and Randolph counties, Illinois , range extensions that ...
[84]
(PDF) Change of Temperature at Sting Site by Scorpion in León ...
Aug 10, 2025 · of medical importance identi ed in Mexico are: Centruroides noxius (considered the most toxic. in the country) found mainly in the State of ...
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IUCN Red List of Threatened Species
Our current goals, based on the IUCN Red List Strategic Plan (2021-2030), are to have 260,000 species assessed and to reassess 142,000 of those species to ...About · 3.1 · Searching The IUCN Red List · Citing The IUCN Red ListMissing: Centruroides | Show results with:Centruroides
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Centruroides vittatus | INFORMATION - Animal Diversity Web
Centruroides vittatus is probably the most frequently encountered scorpion in the United States. The striped scorpions' range radiates outward from Texas.
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Bark Scorpion - Centruroides Sculpturatus - A-Z Animals
Insects make up the vast bulk of a bark scorpion's diet. Some of their favored prey include cockroaches, centipedes, beetles, and crickets. They will also ...<|control11|><|separator|>
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México Deforestation Rates & Statistics | GFW - Global Forest Watch
From 2001 to 2024, México lost 5.2 Mha of relative tree cover, equivalent to a 10% decrease since 2000 and 1.0% of all tree cover loss in global. 13. Sweden.
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Climate change will have an important impact on scorpion's fauna in ...
Climate change will reduce scorpion distribution areas, with some species losing their current range, and some medical species may increase distribution if ...
[91]
Unmasking trends and drivers of the international arachnid trade
Our analysis of the LEMIS data shows that imports of pet arachnids have declined by up to 55% in the past decade.
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[PDF] Mexico-wildlife-trafficking-report-English.pdf
Every year in Mexico, tens of thousands of animals are extracted from the wild for commercial purposes, mainly to be used as pets or food and for their parts, ...
[93]
Scorpion hotspots and their protection status in Mexico. A) Species...
The result of the current situation is the loss of multiple species and an increased risk of human-scorpion conflict that leads to scorpion envenomation (Shahi ...
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Mexican Environmental Conservation Efforts: Great Diversity
Jul 10, 2024 · Hosts 41 biosphere reserves, places that promote sustainable development and environmental education between the local community and protected ...