Fact-checked by Grok 2 weeks ago

Embase

Embase is a comprehensive biomedical and pharmacological database owned and operated by Elsevier, designed to support in-depth literature searches for drug research, pharmacovigilance, systematic reviews, and medical device development.^[1] It provides access to millions of peer-reviewed records, including journal articles, conference abstracts, and clinical trial reports, covering more than 8,200 journals with a focus on international coverage of pharmacology, clinical medicine, and biomedical sciences.^[1]^[2] Originating from the Excerpta Medica abstract journals founded in 1946 in Amsterdam by a group of Dutch physicians, Embase evolved from printed abstract services into a digital database in the 1970s, with electronic records available since 1974.^[3] The database's historical component, known as Embase Classic, extends coverage back to 1947, encompassing over 44 million total records as of 2025.^[1] Unlike MEDLINE, which is produced by the U.S. National Library of Medicine and emphasizes U.S.-centric content, Embase offers broader European and international perspectives, deeper indexing of drug-related literature, and inclusion of approximately 3,200 journals not covered in MEDLINE.^[1]^[4]^[5] Key features of Embase include the Emtree controlled vocabulary thesaurus, which provides precise subject indexing with over 100,000 terms for enhanced search accuracy as of 2025, and daily updates adding around 8,000 new records.^[1]^[6] It supports advanced search tools such as PICO (Population, Intervention, Comparison, Outcome) frameworks, search wizards for systematic reviews, and integration with regulatory compliance needs for pharmacovigilance and medical device safety.^[1] Embase is widely used by researchers, pharmaceutical companies, and regulatory bodies worldwide, recognized for its role in accelerating drug discovery and evidence-based medicine.^[1]

History

Origins as Excerpta Medica

Excerpta Medica was founded in 1946 in Amsterdam by a group of Dutch physicians seeking to facilitate the international exchange of medical knowledge in the aftermath of World War II, when disruptions in scholarly communication had severely limited access to global biomedical literature.^[3]^[7] The initiative addressed the need for a centralized abstracting service to bridge gaps caused by wartime isolation, particularly in Europe, by systematically reviewing and summarizing research from journals worldwide.^[8] The organization launched its first abstract journals in 1947 under the name Excerpta Medica (EM) Abstract Journals, initially covering approximately 15 to 20 biomedical fields through manual abstracting of articles from international peer-reviewed publications.^[8] These journals provided structured summaries in multiple languages, emphasizing fields such as anatomy, physiology, and clinical medicine, with abstracts prepared by a network of volunteer physicians and editors to ensure accuracy and relevance.^[9] By prioritizing comprehensive coverage of European sources alongside global contributions, Excerpta Medica quickly became a vital resource for researchers navigating postwar recovery in medical sciences.^[7] During the 1950s and 1960s, Excerpta Medica expanded rapidly, growing to over 40 specialized abstract journals by the mid-1960s, which encompassed emerging areas like oncology (added in 1953), public health (1955), and cardiovascular diseases (1957).^[8] This development reflected a commitment to broadening the scope of biomedical literature indexing, with staff growing to hundreds of full-time and part-time contributors who manually processed thousands of articles annually from diverse international journals. The focus remained on print-based operations, fostering a robust foundation for medical information dissemination that later paved the way for a transition to digital formats in the 1970s.^[9]

Computerization and Elsevier Acquisition

In 1971, Elsevier acquired Excerpta Medica, integrating its abstracting operations with the publisher's extensive resources in scientific and medical literature, which facilitated the transition to digital formats.^[7]^[3]^[10] This acquisition paved the way for the launch of EMBASE (Excerpta Medica Database) in 1974, marking the first computerized version of the abstracting service and enabling batch searching via magnetic tape distributions.^[7]^[11] From its inception, EMBASE was accessible online through hosts such as Dialog, broadening its reach beyond print-based limitations and supporting real-time queries in biomedical research.^[11] Building on this digital foundation, Elsevier developed Embase Classic in the mid-2000s, releasing it in October 2007 to digitize and index over 1.8 million historical records from the 43 Excerpta Medica abstract journals spanning 1947 to 1973.^[12]^[13] This backfile preserved early biomedical insights, including those from the foundational Excerpta Medica journals, and made them searchable alongside contemporary Embase content for comprehensive literature reviews.^[14]

Content and Coverage

Record and Journal Statistics

Embase contains over 49 million records, encompassing peer-reviewed literature, conference abstracts, and other biomedical sources dating back to 1947, with historical backfiles available through Embase Classic.^[2] This substantial volume includes more than 47.5 million records as highlighted in Elsevier's 2025 roadmap, reflecting ongoing expansions such as the addition of over 500,000 clinical trial records from ClinicalTrials.gov in May 2025.^[15]^[16] In October 2025, an additional approximately 65,000 clinical trial records from ClinicalTrials.gov were added.^[17] The database draws from 8,374 peer-reviewed journals published in 95 countries, ensuring broad international representation in biomedical and pharmacological research (as of September 2025).^[2]^[18] These journals contribute to an average of over 8,000 new records added daily, supporting timely access to emerging literature.^[2] Embase receives daily updates, with comprehensive weekly releases to incorporate the latest content and indexing refinements.^[2]^[19] Since its launch in 1974 as a computerized version of Excerpta Medica, the database has experienced exponential growth through digital enhancements and expanded sourcing, surpassing 40 million records by the early 2020s and continuing to expand into the mid-2020s.^[2] This trajectory underscores Embase's evolution from limited initial holdings to a cornerstone resource for comprehensive biomedical retrieval.^[14]

Subject Scope and Unique Sources

Embase encompasses a broad biomedical scope, covering over 60 topic areas in medicine and related sciences. Its core coverage emphasizes pharmacology, toxicology, drug research and development, medical devices, and clinical trials, which together represent more than 70% of the database's content. These areas are indexed with particular depth, including detailed subheadings for drug interactions, adverse effects, and device classifications such as the Global Medical Device Nomenclature (GMDN). This focus supports comprehensive retrieval of evidence on therapeutic interventions and safety profiles, distinguishing Embase as a key resource for pharmaceutical and clinical inquiries.^[20]^[2]^[19] A hallmark of Embase is its inclusion of unique sources not commonly found in other biomedical databases, such as over 5.6 million conference abstracts from more than 17,000 conferences dating back to 1995. These abstracts provide early access to emerging research presented at international meetings, enhancing the timeliness of literature searches. Additionally, Embase incorporates in-press publications, including preprints from repositories like medRxiv and bioRxiv (added weekly since 2021), as well as regulatory documents such as over 533,000 records from ClinicalTrials.gov (as of September 2025). This integration ensures coverage of pre-publication and trial-specific data essential for tracking drug efficacy and safety.^[2]^[19] Embase maintains a strong international scope, with content drawn from journals published in 95 countries and representing 95 nations in total. Approximately 66% of sourced journals originate outside North America, with a significant portion—around 80% of overall content—coming from non-U.S. sources, including prominent European and Asian publications. This global emphasis facilitates access to diverse perspectives, particularly in pharmacovigilance and regional drug studies.^[2]^[21]^[19] The database also captures elements of gray literature to bolster drug safety monitoring, such as conference proceedings, local literature modules (e.g., the French module covering over 100 journals since 2016), and clinical guidelines embedded in regulatory and trial records. These non-traditional sources complement peer-reviewed journals, providing a more holistic view of evidence that might otherwise be overlooked in standard searches.^[2]^[19]^[22]

Indexing and Search Features

Emtree Thesaurus

Emtree is the proprietary controlled vocabulary and indexing thesaurus developed by Elsevier for Embase, serving as a hierarchically structured system to standardize and enhance the retrieval of biomedical literature. Known formally as the Elsevier Life Science Thesaurus, it encompasses 103,133 preferred terms (including MeSH terms) and 552,048 synonyms, organized across 14 main facets such as anatomy, diseases, and chemicals and drugs, as of September 2025.^[2] This thesaurus is updated regularly, with monthly data checks to incorporate emerging concepts in biomedicine, ensuring relevance to evolving research areas.^[6] The structure of Emtree is hierarchical, allowing terms to be linked through parent-child relationships for precise concept mapping, while synonyms are systematically mapped to their corresponding preferred terms to accommodate variations in terminology. It provides extensive coverage of key biomedical domains, including over 36,000 preferred terms for drugs and chemicals (such as generics, trade names, and investigational compounds), diseases (e.g., infections and myocardial infarction), and devices (e.g., implants and diagnostic equipment).^[6] Unique to Emtree are specialized subheadings that modify concepts, with 64 drug subheadings (e.g., adverse effects, pharmacokinetics), 14 disease subheadings (e.g., drug therapy, side effect), and 4 device subheadings, enabling nuanced indexing of pharmacological and clinical aspects.^[2] A core feature of Emtree is its automatic term mapping, which directs user-entered free-text queries to the most appropriate preferred terms and synonyms, combined with hierarchy explosion to retrieve related narrower or broader terms for comprehensive search results. Each Embase record is indexed with an average of 3-4 major Emtree terms reflecting the article's primary concepts, supplemented by up to 50 minor terms as needed to capture additional facets.^[23] This indexing approach supports multi-faceted searching in advanced Embase queries by facilitating the combination of terms across hierarchies.^[6]

Advanced Search Tools

Embase's search interface facilitates complex literature queries through support for standard Boolean operators—AND, OR, and NOT—which allow users to combine terms logically for precise retrieval.^[24] Proximity operators, such as NEAR/n (where n specifies the maximum word distance between terms, regardless of order) and PRE/n (for terms where the first precedes the second by up to n words), enable searches for conceptually related phrases that may not appear in exact sequences.^[25] Additionally, the interface incorporates the PICO framework via a dedicated search tool that structures queries around Population, Intervention, Comparison, and Outcome elements, automatically adding synonyms and nesting Boolean operators to streamline evidence-based searches.^[26] Unique tools in Embase enhance efficiency for in-depth investigations, including search wizards tailored for systematic reviews, such as the PICO wizard and the pharmacovigilance (PV) wizard, which guide users in building structured queries with predefined strategies.^[27] Citation alerts allow users to set up email notifications or RSS feeds for new records matching saved searches, ensuring ongoing monitoring of emerging literature.^[28] Full-text linking integrates with publisher platforms, providing direct access to articles from 8,374 indexed journals where institutional subscriptions permit, as of September 2025.^[2] Drug-specific features include the PV Wizard, which simplifies queries for adverse events by incorporating trade names, generic names, and regulatory identifiers, alongside pharmacovigilance filters that target terms related to drug safety and side effects.^[29] These tools support targeted retrieval of pharmacological data without requiring manual syntax construction.^[1] To manage content overlaps, Embase employs deduplication algorithms that identify and merge records from MEDLINE sources, preventing duplicate entries on the platform by comparing identifiers like DOIs and publication details during indexing.^[30] This process ensures a unified record set, with the Embase-original version retained where differences exist.^[31] Searches can briefly reference Emtree for automatic term expansion to broaden query coverage.^[1]

Comparison with MEDLINE

Content Overlaps

Embase incorporates all MEDLINE records dating back to 1966, totaling more than 31 million citations as of 2025, and applies parallel indexing using its Emtree thesaurus alongside MEDLINE's MeSH terms to these shared entries.^[32]^[33] This integration ensures comprehensive access to core biomedical literature within Embase, with the database importing unique MEDLINE records directly from the National Library of Medicine while adding its own enhancements.^[34] Approximately 70-80% of Embase's content duplicates MEDLINE, reflecting the substantial overlap in coverage of core biomedical journals that form the foundation of both databases.^[35] This duplication primarily stems from shared indexing of high-impact publications in fields like general medicine and clinical research, allowing users to retrieve the same foundational articles from either resource.^[36] To facilitate efficient searching, Embase flags MEDLINE records through dedicated fields and filters, such as the presence of a PMID or source indicators, enabling users to identify, include, or exclude these entries as needed—for instance, via Ovid's "Exclude MEDLINE journals" option to focus on Embase-unique material.^[37] Additionally, while Embase includes millions of records not found in MEDLINE, such as conference abstracts and international journals, the flagged overlap streamlines deduplication in combined searches.^[18] Pre-1966 biomedical content, which precedes the standard start of MEDLINE coverage, is uniquely available in Embase through its historical backfiles like Embase Classic, spanning from 1947 and encompassing abstracts from early Excerpta Medica journals not systematically included in MEDLINE.^[14] This archival integration provides researchers with access to foundational literature on topics like pharmacology and surgery that would otherwise require separate historical databases.^[2]

Distinct Advantages

Embase distinguishes itself from MEDLINE through its inclusion of unique content that constitutes approximately 20-30% of its total records, encompassing 5.6 million conference abstracts from 17,451 conferences and enhanced coverage of European drug trials via 3,277 journals not indexed in MEDLINE.^[2]^[38]^[35] This non-overlapping material provides access to early-stage research and regional studies often absent from MEDLINE's primarily North American-focused indexing.^[2] In 2025, Embase further expanded with over 330,000 additional conference abstracts and 500,000 ClinicalTrials.gov records, many providing unique indexing not fully paralleled in MEDLINE.^[15]^[39] A key strength of Embase lies in its superior indexing for adverse drug reactions, chemicals, and medical devices, where the Emtree thesaurus employs more extensive and specialized terms compared to MEDLINE's MeSH, enabling more precise retrieval in pharmacovigilance and toxicology contexts.^[34]^[40]^[41] Additionally, Embase incorporates a higher volume of non-English abstracts, broadening its international scope beyond MEDLINE's emphasis on English-language publications.^[42] The Emtree thesaurus enhances search performance in pharmacology by including over 31,000 drug-related terms with comprehensive synonyms and earlier addition of emerging drug names, often retrieving more relevant results than MeSH-based searches in MEDLINE.^[41]^[25] Embase also excels for time-sensitive topics like emerging therapies, as its inclusion of conference abstracts and in-press articles allows for faster access to preliminary findings not yet available in MEDLINE.^[42] While Embase incorporates nearly all MEDLINE content for a shared foundational base, these features position it as a complementary resource for comprehensive biomedical inquiries.^[1]

Applications and Usage

Role in Biomedical Research

Embase serves as an essential resource in biomedical research, particularly for conducting systematic reviews, meta-analyses, and the development of clinical guidelines in evidence-based medicine. Its comprehensive indexing of pharmacological and biomedical literature enables researchers to identify relevant studies on drug interventions, therapeutic efficacy, and clinical outcomes with high precision. For instance, Embase is routinely utilized to synthesize evidence for guideline development by organizations such as the National Institute for Health and Care Excellence (NICE), where it supports the evaluation of intervention effectiveness across diverse populations.^[1]^[18] In practice, Embase is frequently integrated with MEDLINE to ensure comprehensive literature searches, aligning with recommendations from guidelines like PRISMA for transparent reporting in systematic reviews. This combination captures a broader range of studies, with Embase contributing unique records from European, Asian, and pharmacological journals not fully represented in MEDLINE. Studies evaluating search strategies have shown that including Embase alongside MEDLINE increases the retrieval of randomized controlled trials by approximately 5-8% in certain meta-analyses, enhancing the robustness of evidence synthesis.^[43]^[44] Embase's inclusion of over 4.7 million conference abstracts plays a critical role in reducing publication bias within biomedical research, as these abstracts often represent early or unpublished findings that influence meta-analytic results.^[38] This feature is particularly valuable in Cochrane reviews, where Embase helps identify additional trials—especially in drug efficacy evaluations—that can alter conclusions compared to MEDLINE-only searches. By facilitating bias assessment through access to grey literature, Embase supports more reliable evidence-based decisions in clinical research.^[45]^[46]^[47]

Use in Pharmacovigilance and Regulation

Embase plays a pivotal role in pharmacovigilance by providing comprehensive indexing of adverse events through its Emtree thesaurus, which includes dedicated subheadings aligned with regulatory definitions for drug and device safety monitoring. These subheadings, such as those for adverse drug reactions and adverse device effects, enable precise retrieval of literature on suspected adverse reactions, facilitating signal detection in post-market surveillance activities. For instance, Emtree's 64 drug subheadings and 4 medical device subheadings support the identification of drug-disease relations and interactions, essential for assessing rare or emerging safety signals.^[6]^[48] Regulatory authorities, including the European Medicines Agency (EMA) and the U.S. Food and Drug Administration (FDA), recognize Embase as a key resource for pharmacovigilance, particularly for evaluating medical devices and compiling drug approval dossiers. The EMA incorporates Embase into its medical literature monitoring processes, using it alongside MEDLINE to identify individual case safety reports (ICSRs) as outlined in Good Pharmacovigilance Practices (GVP) Module VI. Similarly, FDA pharmacovigilance reviews frequently draw on Embase searches to detect new safety signals, underscoring its endorsement for regulatory compliance and post-approval safety assessments.^[1]^[49]^[50] Embase offers specialized tools, such as the PV Wizard and validated search filters, to enhance compliance by targeting rare side effects and international case reports from its global journal coverage exceeding 8,000 titles. These filters, developed for high sensitivity and precision, retrieve over 80-90% of relevant adverse effects data, including from non-English sources, aiding in the systematic screening required for regulatory reporting. Since the 2012 update to EU pharmacovigilance legislation via Regulation (EU) No 520/2012, which mandated weekly literature screening for individual cases, Embase has been integral to these systems, supporting marketing authorization holders in fulfilling obligations under the EMA's EudraVigilance framework. As of 2025, Embase provides access to over 44 million records for these applications.^[1]^[51]^[2]

Current Status and Developments

Publisher and Accessibility

Embase has been owned and maintained by Elsevier since its acquisition of Excerpta Medica in 1972, which formed the basis for the database's development and ongoing operations.^[3] The database is accessible through multiple platforms, including Elsevier's dedicated Embase.com interface, as well as integrations with third-party vendors such as Ovid from Wolters Kluwer and EBSCOhost.^[1]^[18]^[52] Access to Embase is primarily provided via institutional subscriptions, which are licensed based on factors like the number of concurrent users and the subscribing organization's size, with pricing tailored accordingly; individual or small-business users can opt for limited-duration access periods, and free trial periods are available for academic institutions to evaluate the resource.^[1]^[53] Embase supports global reach, indexing content from journals across more than 90 countries, and features daily updates to maintain timeliness in biomedical literature coverage.^[54]^[2]

Recent Updates and Future Directions

In June 2025, Elsevier launched Embase AI, a generative AI-powered tool integrated into the database that enables natural language querying, automated summarization of search results, and accelerated abstract screening to streamline biomedical literature analysis.^[55] This update builds on prior automatic indexing enhancements introduced in 2023, improving the efficiency of identifying relevant records from Embase's vast repository. A new version of Embase AI was released on November 4, 2025, further refining its capabilities.^[56] A major content expansion occurred in May 2025, when Elsevier incorporated approximately 500,000 records from ClinicalTrials.gov into Embase, followed by ongoing backfills adding tens of thousands more through October 2025 to provide comprehensive coverage of global clinical trials.^[16] These additions, processed at a rate of up to 20,000 trials per day, enhance the database's utility for evidence synthesis in drug development and regulatory submissions.^[56] From 2020 to 2025, Embase's record count grew from over 32 million to more than 44 million, driven by accelerated indexing of COVID-19-related publications and emerging biotechnology literature, reflecting the surge in pandemic-era research output.^[57]^[2] This expansion includes the addition of preprints from the Social Science Research Network (SSRN) in 2025, broadening access to cutting-edge, often open-access content ahead of peer-reviewed publication.^[58] On November 4, 2025, Elsevier announced a collaboration with DistillerSR to integrate Embase's API into DistillerSR's AI-enabled evidence synthesis platform, simplifying the import of Embase search results and enhancing systematic review workflows.^[59] Looking ahead, Embase's 2025 roadmap emphasizes further technological integrations, such as a PubMed-to-Embase query translation tool for seamless cross-database searching and upcoming enhancements to the Embase.com platform for advanced analytics.^[58] The database continues to prioritize open-access materials and comprehensive indexing for medical devices, aligning with evolving EU pharmacovigilance requirements under the Medical Device Regulation (MDR) to support post-market surveillance.^[1] Additionally, regular Emtree updates, such as the January and February 2025 releases adding over 2,000 new terms including disease concepts, ensure ongoing relevance in rapidly evolving biomedical fields.^[60]

References

[1]
Embase | The comprehensive medical research database - Elsevier
Embase is a comprehensive biomedical database that optimizes literature searches. Discover, innovate and develop with confidence.
[2]
Backfile reveals biomedical history - Research Information
Dec 17, 2007 · The history of EMBASE begins with the launch of the Excerpta Medica (EM) Abstract Journals. EM was founded in 1946 in Amsterdam by a group of ...
[3]
Embase - Database Searching Tutorials: Further Information and ...
Jul 23, 2025 · Embase is an international biomedical research database that indexes more than 8,500 journals with 2,700 journal tiles not included in PubMed/ ...
[4]
A brief history of clinical evidence updates and bibliographic ...
In parallel development with these databases was the Excerpta Medica abstracting system, which a group of Dutch physicians began in 1946. It was taken over by ...
[5]
[PDF] Encyclopedia Of Library And Information Science Vol.
Mar 1, 1970 · ... Excerpta Medica. Casimir Borkowski, Associate Professor, Computer ... 20 sections in 1958. This was still, however, a collection of ...
[6]
[PDF] Excerpta Medica
Jul 14, 1980 · The purpose of the Excerp- ts Medics Foundation was to help “the progress of medical knowledge by mak- ing available to medical and related pro ...Missing: founding | Show results with:founding
[7]
[PDF] • -fI • • - Office of Justice Programs
Information Services: The mluIl product of Excerpta Medica is a series of more than 40 abstract journals covering specialized subjects in biomedical and ...<|control11|><|separator|>
[8]
First National Congress of Librarians, Archivists and Documentalists ...
Dialog,. Dimdi and ESA-IRS were the most used hosts accounting for 87% of the total host usage. Extrapolating the results over the whole of. 1984 shows that out ...
[9]
DataStar, Dialog, and Ovid to Host EMBASE Classic Database from ...
Aug 22, 2007 · This EMBASE Classic release will mark the first time that the EMBASE backfile from 1947-1973 will be accessible in electronic form.
[10]
EMBASE Classic in Development - Investegate
... Excerpta Medica Abstract Journals issues published between 1947 and 1973 is currently being scanned. EMBASE Classic will include coverage of articles ...
[11]
Embase Classic - Ovid - Wolters Kluwer
Embase Classic is an essential abstract and index backfile which enables biomedical researchers to review critical research from 1947 to 1973.Missing: 2000s | Show results with:2000s
[12]
Biomedical content coverage in Embase - Elsevier
Get unparalleled coverage of the biomedical literature, with 44M+ records from 8100+ currently published journals.Missing: total | Show results with:total
[13]
[PDF] 2025 roadmap
abstracts to Embase, which now includes a total of more than 47.5 million records. What to look forward to in 2025. The needs and feedback of our customers ...
[14]
Elsevier adds 500K clinical trial records to Embase to enable ...
May 6, 2025 · Elsevier adds half a million records from ClinicalTrials.gov to Embase, enabling a seamless search experience in the world's most comprehensive biomedical ...Missing: total | Show results with:total
[15]
Ovid - Embase | Wolters Kluwer
Nearly 46 million bibliographic records dating back to 1947 · Records drawn from sources published in 90+ countries · Minimal content overlap with other resources ...
[16]
Embase: Excerpta Medica Database Guide - Ovid
Sep 22, 2025 · Embase (Excerpta Medica Database) is a biomedical and pharmacological database produced by Elsevier B.V., containing more than 40 million ...Missing: founded | Show results with:founded<|control11|><|separator|>
[17]
[PDF] EmbasE: what is it and why is it needed?
Embase coverage in a nutshell. • Journal coverage, when embase Classic is included, back to 1947. • Over 28 million records, including 1.8 million records ...Missing: statistics | Show results with:statistics<|separator|>
[18]
Wolters Kluwer | Embase Product Suite on Ovid
Embase is a highly versatile, multipurpose and up-to-date biomedical research database. Embase, produced by Elsevier, is ideal for anyone in the clinical, ...Missing: 1972 | Show results with:1972
[19]
None
### Summary of Embase Indexing Guide 2018
[20]
None
### Summary of Emtree Thesaurus from Embase Indexing Guide 2024
[21]
Emtree life science thesaurus - Elsevier
Emtree is Elsevier's authoritative life science thesaurus. With Emtree indexing, you can use natural language to search thousands of journals and millions ...
[22]
Can I use Boolean operators, wildcards and proximity operators in ...
Sep 2, 2025 · Embase supports several search syntax operators. You can use them in any search form, including Quick Search.Missing: interface | Show results with:interface
[23]
Embase Search Tips - Expert Searching
Oct 7, 2025 · Embase has over 41 million records, including articles from 8,100 peer-reviewed journal titles. Sixty topic areas are covered, including thirty ...Missing: total | Show results with:total
[24]
Embase's Intuitive PICO Search Tool - Becker Medical Library
Oct 23, 2017 · The Embase PICO tool makes database searches easier by integrating complex functions, adding synonyms, and automatically nesting search blocks.Missing: advanced proximity searching notation deduplication
[25]
Advanced Searching in Embase - LibGuides at Oakland University
Sep 5, 2025 · Embase has taken PICO searching in hand with its own PICO search tool. ... and Embase handles the search operators (or Boolean operators).Missing: proximity notation deduplication
[26]
Managing Results and Searches - Embase Help Guide
Aug 27, 2025 · Once you are logged in, you will be able to save your searches and results, and access them under the My Tools link at the top of the screen. My ...Missing: Dialog | Show results with:Dialog
[27]
PV Wizard - Embase - Research Guides at Rutgers University
Feb 2, 2023 · PV Wizard is an intuitive query builder that has a pre-coded search strategy developed with leading industry partners to simplify the pharmacovigilance search ...
[28]
How are Medline articles added to Embase and why can they be ...
Jun 7, 2023 · As there is overlap, a deduplication process is needed to prevent duplicates on the Embase.com platform. In case an Embase record is created and ...Missing: algorithms | Show results with:algorithms
[29]
Can there be duplicate articles in Embase on Ovid?
Specifically for Embase there is an additional source of potential duplicates, as it also ingests NLM's PubMed/MEDLINE that has a very large overlap with Embase ...
[30]
Has Embase replaced MEDLINE since coverage expansion? - PMC
Apr 1, 2018 · Despite the advent of computerized searching offered since the early 1970s by MEDLINE (MEDLARS Online) and Embase (Excerpta Medica) [2], the ...Missing: first | Show results with:first
[31]
What databases does Embase contain? - Elsevier Support
Sep 2, 2025 · The Embase database: Contains biomedical literature from 1974 to present. · The MEDLINE database: Covers journals from 1966 to present.<|control11|><|separator|>
[32]
Embase vs MEDLINE FAQ - Clarivate
Jul 7, 2021 · MEDLINE contains more than 22 million records from 5,600 journals, whereas Embase has over 29 million records from 8,500 journals. Even ...Missing: statistics | Show results with:statistics
[33]
Choosing a Database: Home
Apr 29, 2025 · Embase journal coverage is from 1947 on with historical records included in Embase Classic. 45.6 million records and over 12 million records ...
[34]
View of Has Embase replaced MEDLINE since coverage expansion?
In 2017, Elsevier, the parent company of Embase, suggested that Embase had 2,800 unique journal titles, while MEDLINE had 2,500, with the 2 databases sharing ...Has Embase Replaced Medline... · Conclusion · Introduction
[35]
Excluding Medline citations from Embase results - LibGuides
Sep 5, 2022 · Excluding Medline citations will exclude the majority of PubMed citaitons. Remember PubMed includes not only Medline but other sources.Missing: flags | Show results with:flags
[36]
Which conferences are covered in Embase? - Elsevier Support
Oct 6, 2025 · It currently indexes 12,000+ conferences covering over 4.7 million conference abstracts - advanced information that can't be found searching ...
[37]
Drug Adverse Event Searching Made Easier By MEDLINE and ...
Aug 8, 2016 · Unlike MEDLINE, however, EMBASE also indexes conference proceedings from over 5600 conferences and it uses the Emtree thesaurus instead of MeSH ...
[38]
Emtree (Embase subject headings) - LibGuides - University of Toledo
Sep 5, 2022 · Emtree is a list of subject headings unique to Embase. Biomedical terms are organized by broader and narrower terms for most subjects ...
[39]
PubMed vs. Embase in Literature Review and Analysis: A Medical ...
Oct 22, 2024 · Coverage of Non-U.S. Clinical Guidelines: Embase often provides more comprehensive coverage of European and international clinical ...Missing: percentage | Show results with:percentage
[40]
Optimal database combinations for literature searches in systematic ...
Dec 6, 2017 · The combination of Embase, MEDLINE, Web of Science Core Collection, and Google Scholar performed best, achieving an overall recall of 98.3 and ...
[41]
Using Embase as a supplement to PubMed in Cochrane reviews ...
Embase combined with PubMed covered 48,326 out of 54,901 studies and thus had a coverage rate of 88.0%, 95% CI [86.2, 89.9] of studies. The results also showed ...
[42]
Systematic searching in Ovid Embase: understanding the MEDLINE ...
Apr 27, 2022 · This paper shows how the document collections on Ovid Embase can be used to limit searches and isolate the unique content from MEDLINE that is available on ...Missing: percentage | Show results with:percentage
[43]
How should systematic reviewers handle conference abstracts ... - NIH
Nov 7, 2019 · The main argument for including conference abstracts in systematic reviews is that abstracts with positive results are preferentially published, and published ...
[44]
Should meta-analysts search Embase in addition to Medline?
We explore whether searching Embase yields additional trials that influence a meta-analysis. We identified meta-analyses that searched Medline and Embase.<|control11|><|separator|>
[45]
What are subheadings in Embase? - Elsevier Support
Jan 13, 2020 · The drug subheadings for pharmacovigilance are aligned with EMA and FDA definitions. The scope notes are listed below: ; adverse device effect.<|separator|>
[46]
[PDF] Guideline on good pharmacovigilance practices (GVP) - Module VI
Jul 28, 2017 · This Module of GVP addresses the legal requirements detailed in Directive 2001/83/EC [DIR] and. Regulation (EC) No 726/2004 [REG], ...
[47]
[PDF] 761432Orig1s000 - accessdata.fda.gov
Jun 5, 2025 · ... Pharmacovigilance ... Embase and PubMed for new safety signals. • Required, periodic safety reports submitted by the manufacturer. • Review ...
[48]
Updated generic search filters for finding studies of adverse drug ...
Jun 7, 2022 · We have derived and validated search filters that retrieve around 90% of records with adverse drug effects data in medline and Embase.
[49]
EBSCOhost/ EMBASE - Research Information
Hospitals can now access Elsevier's biomedical bibliographic database EMBASE on the EBSCOhost database platform.
[50]
New Database Trial Available: Embase - Falvey Library Blog
May 25, 2021 · Falvey Library is pleased to offer a summer trial to Elsevier's Embase. This science database provides comprehensive coverage of biomedical information.
[51]
Research Guides: Embase Help Guide: Home
Oct 13, 2025 · Once we have searched all three terms, we can combine them together using the And button below the search history box. Embase search history.Missing: Dialog | Show results with:Dialog
[52]
Elsevier introduces Embase AI to transform how users draw critical ...
Jun 25, 2025 · Embase AI transforms access to biomedical research with natural language search and summarization of millions of biomedical literature records.Missing: 2023 | Show results with:2023
[53]
Embase Release Notes - Elsevier Support
These additional clinical trial records will be added between 13th October to 16th October 2025. We will be adding 20,000 trials per day and the process will ...Missing: total | Show results with:total
[54]
EMBASE - Research Guides
New as of October 21, 2020. EMBASE Features: *Journal coverage from 1947 to the present *Over 32 million records, including MEDLINE titles *Over 8,500 ...Missing: statistics | Show results with:statistics
[55]
Embase 2025 Roadmap: Discover What's New and What's Ahead in ...
In this session, we will introduce the latest content sources added to Embase, including preprints from the Social Science Research Network (SSRN) and clinical ...Missing: 2023 2024
[56]
EMTREE's February 2025 Update Provides Latest Biomedical ...
Feb 18, 2025 · February 17, 2025: EMTREE's February 2025 Update Provides Latest Biomedical Searching Terminology · A total of 436 new disease concepts, ...<|control11|><|separator|>