Halotherapy, also known as salt therapy, is a non-pharmacological treatment that involves the inhalation of dry sodium chloride (salt) aerosol particles in a controlled environment, such as a salt room or chamber, to mimic the microclimate of natural salt caves.[1] This therapy disperses fine salt particles (typically less than 5 micrometers in size) at concentrations of 10-30 mg/m³, with sessions lasting 30-60 minutes over a course of 10-20 treatments, aimed at improving respiratory and dermatological conditions by enhancing mucociliary clearance and reducing inflammation.[2]Originating in the 19th century as speleotherapy—the therapeutic use of natural salt mine environments in Eastern Europe for respiratory ailments—halotherapy has evolved into modern artificial adaptations using halogenerators to produce dry salt aerosols, distinct from wet salt inhalation methods like nebulized hypertonic saline.[1] The mechanism involves the hygroscopic properties of salt particles, which draw water into the airways to hydrate and thin mucus, facilitate expectoration of pathogens and allergens, and exhibit antibacterial effects by inhibiting microbial growth and boosting phagocyte activity.[2] It is primarily applied to chronic respiratory disorders such as asthma, chronic obstructive pulmonary disease (COPD), and bronchiectasis, as well as skin conditions like psoriasis and atopic dermatitis, with sessions promoting relaxation and overall well-being.[1]Clinical evidence for halotherapy's efficacy is mixed, with some studies demonstrating benefits in asthma management, including improved forced expiratory volume in one second (FEV1) by up to 20-30% and reduced bronchial hyperreactivity after treatment courses; however, halotherapy is considered a complementary therapy and lacks approval from regulatory authorities such as the U.S. Food and Drug Administration (FDA) for diagnosing, treating, or preventing specific diseases.[1][3] For instance, hypertonic saline inhalation—a related wet form—has shown enhanced peak expiratory flow rates (PEFR) and symptom relief in acute asthma exacerbations when combined with bronchodilators.[1] However, other research, such as a randomized trial in non-cystic fibrosis bronchiectasis patients, found no significant improvements in pulmonary function tests or quality of life after two months of dry salt inhalation using a portable device.[4] Overall, while halotherapy is generally safe with minimal side effects like mild throat irritation, larger, long-term randomized controlled trials are needed to establish its role as an adjunct therapy, as current evidence is limited by small sample sizes (often 20-100 participants) and short durations.[1][4]
Overview
Definition and Principles
Halotherapy is a therapeutic practice involving the exposure to dry sodium chloride (salt) aerosols or microparticles, primarily through inhalation and skin contact, aimed at promoting health benefits. It serves as an artificial adaptation of speleotherapy, the traditional method of utilizing the natural microclimate of salt caves or mines for therapeutic purposes.[5]The core principles of halotherapy revolve around replicating the controlled environment of subterranean salt formations, where dry salt particles—typically ranging from 1 to 5 microns in diameter—are dispersed into the air to facilitate deep respiratory penetration and surface interaction.[6] These particles are generated to mimic the aerosolized salt naturally present in salt mine atmospheres, creating a hypoallergenic setting conducive to therapy.[7]Halotherapy specifically emphasizes dry salt inhalation, distinguishing it from related practices such as brinetherapy, which employs wet saline solutions for nebulization, gargling, or immersion. Essential components include dedicated salt rooms lined with salt crystals and equipped with a halogenerator—a specialized device that grinds pharmaceutical-grade salt into the requisite microparticles and disperses them evenly. Sessions generally last 30 to 60 minutes, allowing sufficient exposure time within the therapeutic environment.[8][9][10]
Proposed Mechanisms
Halotherapy is posited to enhance mucociliary clearance in the respiratory tract primarily through the hygroscopic properties of inhaled sodium chloride (NaCl) aerosols, which draw water into the airways to hydrate and thin mucus, thereby facilitating its expulsion and the removal of trapped pathogens.[1] This process disrupts ionic bonds in mucus, improving its rheology and stimulating ciliary beat frequency to promote more efficient transport along the epithelial surface.[1] Additionally, the fine salt particles (typically 2-5 micrometers in size) penetrate deep into the bronchi, supporting mucociliary transport without causing irritation.[11]The anti-inflammatory effects of halotherapy are attributed to the modulation of inflammatory pathways by NaCl aerosols, which inhibit the activation of the NLRP3/ASC/Caspase-1 signaling cascade, thereby reducing the production of pro-inflammatory cytokines such as IL-1β and TNF-α.[12] This leads to decreased airway edema and infiltration of inflammatory cells, alleviating hypersensitivity in conditions like asthma.[5] Furthermore, salt particles are thought to lower immunoglobulin E (IgE) levels and suppress histamine release, contributing to reduced allergic inflammation.[11]Antibacterial properties arise from the high osmotic pressure exerted by NaCl particles, creating an environment that dehydrates and inhibits the growth of bacteria and fungi in the respiratory mucosa.[11] The aerosols also promote phagosomal acidification within immune cells, enhancing the formation of hypochlorous acid to combat pathogens such as Escherichia coli and Klebsiella pneumoniae.[1] This mechanism bolsters non-specific immunity by stimulating neutrophil bactericidal activity.[5]At the skin level, the hygroscopic nature of dry NaCl aerosols absorbs excess moisture from inflamed tissues, reducing edema and creating a drier environment that discourages microbial proliferation in conditions like eczema.[13] This absorption normalizes skin pH, improves microcirculation, and enhances cellular permeability, thereby diminishing inflammation and promoting tissue regeneration.[13] The anti-inflammatory action further mitigates symptoms such as itching and lichenification by stimulating electrophysiological activity in skin cells.[13]Some proponents suggest that airborne salt particles carry a negative charge, which may contribute to therapeutic effects, though scientific evidence for ionization-related benefits remains limited.[14]While these mechanisms are proposed based on available studies, larger clinical trials are needed to confirm their efficacy.
History
Ancient and Early Uses
The origins of salt-based therapies trace back to ancient Greece, where natural environments rich in salt, such as coastal areas and mineral springs, were utilized for health benefits, including respiratory relief based on later historical interpretations. The physician Hippocrates (c. 460–370 BCE) recommended seawater baths and exposure to salt-laden environments to alleviate various ailments, attributing benefits to the purifying effects of salt, though specific inhalation of seawater vapors for respiratory conditions like asthma and bronchitis is not documented in primary sources.[15][16]In the Roman era, therapeutic practices expanded to include immersion in saline waters and exposure to salt-infused environments in public baths, which were prescribed for various health issues including lung conditions based on traditional accounts, though specific use of salt caves remains undocumented in primary classical sources. Medieval European folklore, particularly in salt-rich regions of Poland and Austria, emerged from observations in active mines like the 13th-century Wieliczka Salt Mine, where workers anecdotally reported reduced incidence of respiratory illnesses due to the dry, salt-saturated air, leading to informal therapeutic excursions by locals seeking similar relief.[17][18]By the 19th century, these traditional observations gained medical attention through Polishphysician Feliks Boczkowski, who in the early 19th century noted the notably low rates of lung diseases among Wieliczka Salt Mine workers compared to coal miners and established the first subterranean health resort there in 1839, formalizing speleotherapy—the precursor to modern halotherapy—as a treatment involving prolonged stays in salt caverns.[19][20]Parallel to inhalation practices, early non-inhalation applications in Eastern Europe involved salt baths and compresses derived from brine solutions for treating skin conditions such as eczema and wounds, with Boczkowski incorporating such methods into his sanatorium offerings to promote healing through direct salt contact.[21][22]
Modern Development
The foundations of modern halotherapy trace back to the late 19th and early 20th centuries, when observations of respiratory benefits among salt mine workers led to the establishment of speleotherapy clinics in Eastern European salt mines. In Poland, the Wieliczka Salt Mine began offering therapeutic stays as early as 1839, initially focusing on brine baths for various ailments, with post-World War II developments emphasizing underground stays for tuberculosis patients. Similarly, in Ukraine, the first dedicated speleotherapy hospital opened in the Solotvyno Salt Mine in 1968, providing controlled environments for treating respiratory conditions like tuberculosis through prolonged exposure to salt-saturated air. These clinics marked a shift from anecdotal uses to structured medical applications, laying the groundwork for halotherapy's evolution.[23][24][18]During the Soviet era, significant advancements occurred in the 1980s with the development of artificial halotherapy to replicate mine conditions outside natural sites. Dr. Alina Chervinskaya, a prominent pulmonologist in Russia, pioneered this approach by creating controlled saltaerosol environments, including the invention of halogenerators—devices that grind pharmaceutical-grade salt into fine particles for inhalation. The first such device was developed in 1985 at the Institute of Balneology in Odessa (then part of the Soviet Union), enabling halotherapy sessions in above-ground chambers and broadening access beyond remote mines. Chervinskaya's work, supported by clinical trials, established halotherapy as a rehabilitative therapy for respiratory diseases, influencing protocols still used today.[25][22][21]Following the dissolution of the Soviet Union in the early 1990s, halotherapy underwent rapid commercialization in Eastern Europe, where clinics proliferated in countries like Poland, Ukraine, and Russia. By the early 2000s, the practice expanded westward, integrating into spas and wellness centers in Western Europe, Canada, and Australia as a non-invasive complementary therapy. In the United States, the first commercial salt rooms emerged in the 2010s, with facilities like The Salt Room opening in 2010 and sparking nationwide growth, driven by demand for alternative wellness options. This period saw halotherapy transition from medical settings to consumer-oriented services, with over 2,000 salt therapy centers worldwide by the mid-2010s.[21][26][27]Regulatory recognition varies globally, with halotherapy classified as a complementary therapy in parts of the European Union, where it is integrated into wellness practices under balneotherapy guidelines, though not as a standalone medical treatment. In the United States, as of 2025, the FDA has not approved halotherapy for diagnosing, treating, or preventing any disease, positioning it strictly as a wellness modality rather than a regulated medical intervention. Recent trends since the 2010s include its incorporation into wellness tourism, with salt rooms featured in luxury hotels and resorts to attract health-conscious travelers seeking natural therapies. Concurrently, online certification programs for practitioners have proliferated, offered by organizations like the Salt Therapy Association, providing self-paced training on halotherapy protocols to standardize practices in the growing industry.[28][29][30][31]
Methods and Forms
Dry Halotherapy
Dry halotherapy, the primary modern form of this therapy, is performed in dedicated salt therapy rooms designed to simulate a controlled salt microclimate. These rooms typically feature walls and ceilings coated with layers of salt, creating an aesthetically immersive space that enhances the overall experience. Central to the setup is the halogenerator, a specialized device that grinds pharmaceutical-grade sodium chloride into fine dry aerosol particles, usually ranging from 1 to 5 microns in size for optimal inhalation into the respiratory tract.[32][33] The halogenerator disperses these particles into the air at precisely controlled concentrations, typically between 1 and 10 mg/m³, ensuring consistent exposure throughout the session.[34]In a standard procedure, participants sit or recline comfortably in the room while breathing the aerosolized salt air, with sessions lasting 30 to 60 minutes to allow sufficient time for particle deposition in the airways.[2] Patients are advised to relax, often engaging in deep breathing or meditation, as the dry environment promotes passive inhalation without physical exertion. For individuals addressing chronic conditions, a regimen of 10 to 20 sessions spread over several weeks is commonly prescribed to build cumulative exposure.[35]Variations of dry halotherapy include portable halogenerators designed for home or smaller-scale use, which can generate salt aerosols in personal spaces like bedrooms or tents, though they achieve lower particle concentrations and uniformity compared to professional rooms.[36]Homesalt lamps, while providing ambient negative ions and a calming glow, do not produce the micron-sized dry salt aerosols required for true halotherapy and are thus considerably less effective for this purpose.[37]To maintain efficacy, the therapy environment incorporates specific controls: room temperatures are kept between 18 and 24°C, and relative humidity is regulated to 40 to 60%, conditions that prevent particle clumping and facilitate prolonged suspension in the air.[11] These parameters differ from wet salt therapy methods, which involve saline solutions rather than dry dispersions.
Wet Salt Therapy and Natural Methods
Wet salt therapy methods involve the inhalation of humidified salt aerosols generated from saline solutions, distinct from dry halotherapy. These are typically delivered through nebulizers or in steam rooms to facilitate absorption in the respiratory tract. Such methods incorporate liquid components, allowing for the use of hypertonic saline concentrations ranging from 3% to 7% sodium chloride (NaCl), which promote mucolytic effects and hydration of airways. Nebulizers convert the saline into a fine mist for targeted delivery, often administered in sessions lasting 10-20 minutes, and are commonly used in clinical settings for respiratory support.[38][39]Brine therapy, a related approach, integrates saltwater baths, soaks, or gargles to expose the skin, mucous membranes, and throat to saline solutions, enhancing topical and oropharyngeal benefits. These applications typically employ isotonic or hypertonic brines, such as 2-3% NaCl dilutions derived from natural salt sources, and may be combined with inhalation sessions for comprehensive exposure. Gargling with saltwater, for instance, utilizes simple 0.9-3% solutions to soothe inflammation, while baths involve immersing in 1-2% saline for skinabsorption, often recommended for adjunctive relief in respiratory and dermatological contexts.[40][41]Natural methods of halotherapy, known as speleotherapy, rely on immersion in the unaltered microclimate of salt mines or caves, where high humidity, stable temperatures (around 14-18°C), and natural salt aerosols provide passive exposure without mechanical aids. Prominent sites include the Wieliczka Salt Mine in Poland, operational since the 13th century and adapted for therapy since the 1950s, and the Solotvyno Salt Mine in Ukraine, which hosted the world's first speleo-hospital in 1968. Sessions in these environments typically last days to weeks, with participants resting in chambers or engaging in light activities like walking along mine corridors to promote prolonged inhalation of the mineral-rich air.[42][43]Procedural differences between wet salt therapy and natural methods highlight their distinct approaches: wet methods employ medical-grade nebulizers for precise, controlled dosing of saline aerosols in clinical or home settings, ensuring consistent particle size and concentration for upper and lower airway targeting. In contrast, speleotherapy involves uncontrolled natural conditions, where participants hike or repose in underground galleries, benefiting from variable aerosol levels influenced by mineventilation and depth, often requiring extended stays for cumulative effects.[44][40]
Claimed Therapeutic Applications
Respiratory Conditions
Halotherapy is promoted by practitioners as a supportive therapy for various respiratory conditions, primarily through the inhalation of dry salt aerosols that purportedly facilitate mucus clearance and reduce airway inflammation. For asthma management, it is claimed to decrease bronchospasm episodes and enhance overall lung function by thinning bronchial secretions, allowing for easier expulsion and improved airflow.[8][34] These effects are said to provide symptomatic relief, enabling better daily activities and reduced reliance on rescue inhalers in some cases.[19]In chronic obstructive pulmonary disease (COPD), halotherapy is asserted to alleviate key symptoms such as wheezing, chronic cough, and shortness of breath by promoting the liquefaction of viscous mucus and decreasing bronchial obstruction.[7][8] Practitioners report that regular sessions can lead to improved oxygen saturation and enhanced exercise tolerance, offering a non-pharmacological complement to standard treatments.[19] The therapy's anti-inflammatory properties are highlighted as particularly beneficial for managing exacerbations in COPD patients.[34]For bronchitis and sinusitis, both acute and chronic forms, halotherapy is claimed to reduce inflammation in the airways and sinuses, thereby lowering the frequency and severity of infections.[45] In bronchitis, it purportedly aids in clearing excess mucus from the lungs, shortening recovery time during acute episodes, while in sinusitis, the salt particles are said to cleanse nasal passages and decrease congestion.[19][8] These actions are believed to create a more hospitable environment in the respiratory tract, potentially reducing recurrent flare-ups.[34]Halotherapy is also positioned as a supportive measure for allergies and cystic fibrosis, where it may assist in allergen desensitization by stabilizing mast cells and reducing histamine release in allergic rhinitis or hay fever.[8] In cystic fibrosis, the therapy is claimed to thin tenacious sputum, facilitating better clearance and decreasing the incidence of pulmonary infections through its mucolytic and antibacterial effects.[19][34] These benefits are thought to stem from enhanced mucociliary action, as outlined in the proposed mechanisms of halotherapy.[45]Emerging claims as of 2025 include benefits for post-COVID-19 respiratory symptoms and acute respiratory distress syndrome (ARDS), where halotherapy is promoted to improve lung function, reduce inflammation, and aid recovery from persistent thoracic pathology.[46][47][48]Typical usage protocols recommended by practitioners involve 10-15 sessions for acute respiratory relief, with each session lasting 15-45 minutes in a controlled salt environment.[34] For chronic conditions like COPD or cystic fibrosis, maintenance therapy often consists of 2-3 sessions per week over 20-30 sessions initially, followed by periodic boosters to sustain benefits.[7][8]
Dermatological and Other Conditions
Halotherapy has been purported to offer benefits for several dermatological conditions due to the exfoliating and anti-inflammatory effects of dry salt particles, which can penetrate the skin to reduce plaques, rashes, and irritation. In psoriasis, salt aerosol is claimed to dissolve central plates, decrease infiltration, and improve symptoms during the maintenance phase of treatment.[13] For eczema and atopic dermatitis, it reportedly alleviates itching, lichenification, dryness, and overall rash severity in 65-75% of patients, promoting skin regeneration and pH normalization.[13][2] These effects stem from salt's ability to enhance microcirculation and reduce inflammation on the skin surface.[8]Acne and other forms of dermatitis are also targeted by halotherapy's antibacterial properties, which are said to lower bacterial load, unclog pores, and support healing in comedogenic conditions like rosacea.[13][8] Proponents assert that the fine salt particles act as a gentle exfoliant, removing dead skin cells and fostering a balanced skin environment to minimize breakouts and irritation.[8]In addition to skin applications, halotherapy sessions are claimed to address stress and sleep disorders through the relaxing atmosphere of salt rooms, which encourages meditation and reduces overall tension.[19] This relaxation is attributed to negative ions produced during therapy, potentially improving mood and alleviating insomnia.[49] Surveys indicate significant enhancements in sleep quality and relaxation after regular sessions, with over 92% of participants reporting overall health improvements.[49]Broader claims include immune support via halotherapy's anti-allergic effects, which may provide relief from seasonal allergies by reducing inflammation and supporting respiratory and skin responses.[8] General detoxification is also promoted, with salt particles purported to aid in clearing toxins and boosting phagocyte activity for non-disease-specific wellness.[50]In non-medical contexts, halotherapy features prominently in spa and beauty treatments, where it is used to enhance skin hydration, elasticity, and texture for anti-aging purposes.[19][8] These sessions are said to repair skin cells, protect against premature aging, and reduce wrinkles by improving moisture retention and minimizing inflammatory damage.[8]
Scientific Evidence
Clinical Studies and Findings
Clinical studies on halotherapy have primarily focused on its potential benefits for respiratory conditions, with several peer-reviewed reviews and trials examining outcomes such as lung function and symptom reduction. A 2021 comprehensive review published in Healthcare analyzed multiple studies on halotherapy as an adjuvant therapy for asthma, reporting improvements in forced expiratory volume in one second (FEV1) among patients; for instance, one trial using a dry-salt inhaler over four months (20 minutes daily) showed a 4% increase in FEV1. A separate study on hypertonic saline inhalation reported enhanced mucociliary clearance (23.4% improvement vs. 8.9% baseline, p < 0.005).[1] These findings suggest halotherapy may support better airflow and reduced inflammation in asthma patients after regular sessions, though typically involving 10-20 exposures. For chronic obstructive pulmonary disease (COPD), small randomized controlled trials (n=20-50) have indicated reduced exacerbations and modest gains in pulmonary function; a 2014 systematic review in the International Journal of COPD highlighted studies where FEV1 improved from 1.47 L to 1.68 L after treatment, with up to 95% of participants reducing or omitting medications, based on case-control designs from facilities in Eastern Europe.[7]Research on dermatological applications, particularly psoriasis, has shown promising results in symptom alleviation through combined wet and dry halotherapy approaches. A clinical study evaluating halotherapy's impact on psoriasis vulgaris reported clinical remission in approximately 65% of participants following a course of treatment, attributed to the anti-inflammatory and antibacterial properties of salt aerosols that promote skin regeneration and reduce scaling.[51] This outcome aligns with broader observations in skin trials where halotherapy enhanced epidermal barrier function and decreased lesion severity, though long-term remission rates varied.Evidence for other applications, such as allergy relief, remains limited but points to potential symptom mitigation. A 2016 analysis by the American Lung Association reviewed available data and noted preliminary support for reduced nasal congestion and irritation in allergic rhinitis, though high-quality meta-analyses are lacking and effects are often described as adjunctive rather than curative.[20] Positive but small-scale studies have also explored stress reduction, indicating possible relaxation benefits via improved breathing and environmental calming, though these require larger confirmatory trials.[52]Methodologically, the majority of halotherapy studies prior to 2020 originated from Eastern European countries like Poland and Ukraine, featuring sample sizes typically under 100 participants and relying on non-randomized or case-control designs. Recent Western trials from 2023-2025, such as a 2024 Italian survey involving over 200 participants using aerosol-based halotherapy, have assessed self-reported improvements in respiratory and skin symptoms after 10 sessions while emphasizing the need for standardized protocols. A June 2025 study found halotherapy improved outcomes in acute respiratory distress syndrome (ARDS) patients by reducing inflammation and pyroptosis-related biomarkers.[49][47]
Limitations and Criticisms
The scientific evidence supporting halotherapy remains limited, with the majority of studies suffering from methodological weaknesses such as small sample sizes, lack of double-blind randomized controlled trials (RCTs), and absence of standardized protocols. A 2024 review by Medical News Today highlighted that while some preliminary research suggests potential benefits for mucus clearance in respiratory conditions, the overall body of evidence is inconclusive due to insufficient large-scale, high-quality investigations. Similarly, a 2025 analysis from the Cleveland Clinic emphasized that there are no rigorous clinical trials validating key claims, with experts noting the need for more robust research to differentiate halotherapy from placebo responses.[45][19]Critics argue that observed benefits may largely stem from the placebo effect, facilitated by the relaxing, spa-like environment rather than the salt particles themselves. The calming atmosphere, including dim lighting and quiet sessions, could account for reported improvements in well-being and stress reduction, as suggested in evaluations from both Medical News Today and the Cleveland Clinic, where experts indicated that similar effects might be achieved through meditation alone without salt exposure. Additionally, confounding factors such as variations in humidity, air quality, and session duration complicate attributions of efficacy specifically to sodium chloride aerosols.[45][19]Halotherapy is classified as a wellness practice rather than a medical treatment, lacking endorsement from regulatory bodies like the U.S. Food and Drug Administration (FDA) for therapeutic claims as of 2025. Industry disclaimers routinely state that the FDA has not evaluated halotherapy's efficacy for diagnosing, treating, or preventing diseases, allowing unsubstantiated marketing without oversight akin to pharmaceuticals. This regulatory gap has drawn skepticism from organizations such as the American Lung Association, which in 2025 reiterated that halotherapy has no established medical guidelines and requires large-scale studies to substantiate benefits, viewing it as unproven for lung conditions.[29][53][53]Commercial interests further undermine research credibility, with much of the positive data originating from industry-funded or small-scale studies that overrepresent favorable outcomes while minimizing mixed or negative results. A 2018 critique in Science-Based Medicine described halotherapy as pseudoscience propagated by the spa sector to capitalize on wellness trends, exploiting vague claims to attract consumers without rigorous validation. Post-2010 studies, including those from 2021 and 2022, have shown inconsistent results that are often overlooked in promotional materials, highlighting a bias toward anecdotal endorsements over comprehensive scientific scrutiny.[54][55][1]
Safety and Contraindications
Potential Risks and Side Effects
Common side effects of halotherapy include temporary throat irritation, coughing, and skin dryness, particularly during initial sessions as the respiratory tract and skin adjust to the salt aerosol. These effects are typically mild and resolve within a few sessions without intervention. Increased mucus production may also occur as nasal passages clear, aiding in the expulsion of irritants but potentially causing discomfort initially.Respiratory risks are generally low but can include bronchospasm in sensitive individuals, which may exacerbate wheezing or shortness of breath in those with underlying airway hyperreactivity. Sore throat sensations have been noted after prolonged exposure beyond 15 minutes in some studies on dry salt inhalers.Allergic reactions are rare but may manifest as salt sensitivity leading to hives or wheezing in predisposed individuals, often due to irritation of mucous membranes by the aerosolized particles.Long-term concerns involve potential dehydration from the hygroscopic properties of salt, which draw moisture from the body, and risks of dustinhalation in poorly maintained facilities where salt particles accumulate and become airborne contaminants. As of 2025, recent reviews confirm these side effects remain mild and transient, with no new significant risks identified.[45]To mitigate these risks, participants are advised to maintain hydration by drinking water before and after sessions, and exposure should be limited to no more than one hour per session to prevent excessive irritation or dehydration.
Precautions for Specific Populations
Halotherapy is contraindicated for individuals with acute infections or contagious diseases, due to the risk of exacerbating symptoms in a confined environment.[56] Similarly, it should be avoided by those with hyperthyroidism, severe hypertension (stages II-III), or open wounds, as the dry salt particles may irritate the skin or thyroid or elevate blood pressure.[56]Pregnant individuals should approach halotherapy with caution, as there is limited research supporting its safety during pregnancy, and consultation with a healthcare provider is recommended before participation.[57] For children under 12 years old, while generally considered safe when supervised, parental accompaniment is required for younger children.[5] Individuals with claustrophobia may find halotherapy challenging, particularly in enclosed cave-like settings, and alternative open-air salt therapy options should be considered.[56][19]Patients with chronic obstructive pulmonary disease (COPD), especially those requiring oxygen therapy, need close medical monitoring during sessions, as severe cases may lead to respiratory complications despite potential benefits in milder forms.[25] Cancer patients, particularly those with malignant respiratory diseases or undergoing chemotherapy, are advised to consult their oncologists, as halotherapy is contraindicated in advanced stages due to risks of irritation or interference with treatment.[56]Prior to any halotherapy session, a thorough health screening by a qualified practitioner is essential to identify contraindications, and at-risk individuals should assess tolerance cautiously.[45] Additionally, natural salt cave environments may not be accessible for those with mobility impairments, necessitating the use of simulated salt rooms instead.[19]