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Intercostal muscles

The intercostal muscles are a group of skeletal muscles situated in the 11 intercostal spaces between the of the thoracic cage, forming an essential component of the . They are organized into three distinct layers—external, internal, and innermost—each with specific fiber orientations that contribute to their coordinated actions. Primarily, these muscles facilitate by altering the dimensions of the : the external intercostals elevate the during to increase thoracic volume, while the interosseous portions of the internal intercostals and the innermost intercostals depress the during expiration to reduce it. The form the most superficial layer, spanning from the inferior border of one to the superior border of the below, with fibers directed inferomedially; they are most prominent laterally and absent near the where the external intercostal substitutes. Beneath them lie the internal intercostal muscles, oriented superolaterally and running perpendicular to the external layer, originating from the costal groove of the upper and inserting into the lower ; these are divided into interosseous portions (dorsally) that aid in during expiration and respiratory portions (ventrally) that assist in during . The deepest innermost intercostal muscles, separated from the internal layer by neurovascular bundles, run parallel to the internal intercostals and are covered by , functioning mainly as synergists in . Collectively, these 11 pairs of muscles on each side reinforce the and support movements beyond , such as coughing and forced . Innervated by the (anterior rami of thoracic spinal nerves T1–T11), the intercostal muscles receive sensory and motor input that coordinates their with diaphragmatic activity during quiet , though they become more active in labored respiration. Blood supply is provided by the posterior intercostal arteries (branches of the or supreme intercostal artery) and anterior intercostal arteries (from the ), ensuring oxygenation for sustained respiratory demands. Clinically, these muscles are relevant in procedures like intercostal nerve blocks for and chest tube insertions, where precise anatomical knowledge prevents injury to the running along the inferior border.

Anatomy

Location and Organization

The intercostal muscles are situated within the 11 intercostal spaces formed between the 12 pairs of that constitute the thoracic cage. These spaces are bounded superiorly and inferiorly by the , with the muscles spanning from the inferior border of one rib to the superior border of the rib immediately below, providing structural support and facilitating movement of the thoracic wall. In each space, the intercostal muscles form three distinct layers arranged from superficial to deep: the external intercostal, internal intercostal, and innermost intercostal muscles. The organization of these layers divides each into three compartments. The external intercostal layer occupies the most superficial compartment, while the internal and innermost layers create the deeper divisions; the —comprising the intercostal vein, artery, and nerve—courses posteriorly within the costal groove along the inferior border of the , positioned between the internal and innermost intercostal muscles. Anteriorly, the primary muscular mass is concentrated, contributing to the overall compartmental arrangement that protects vital structures and enables coordinated rib motion. In the first intercostal space, between the first and second , the muscles are modified due to the attachment of the first rib to the manubrium of the , with the attaching to and elevating the first two . In the lower intercostal spaces, including between the eleventh and twelfth , the arrangement is modified posteriorly by the subcostal muscles, which extend across two or three .

External Intercostal Muscles

The external intercostal muscles constitute the outermost layer of the three intercostal muscle groups within the , spanning the spaces between the . Each muscle originates from the lower of the above, encompassing the costal groove, and inserts onto the upper of the immediately below, thereby connecting adjacent across the 11 intercostal spaces. The fibers of the run obliquely in a downward and forward direction, differing from the opposing upward and backward orientation of the internal intercostal fibers. This arrangement allows the muscles to extend posteriorly from the rib tubercles to the costochondral junctions, where they remain visible in the anterior intercostal spaces without reaching the . Anteriorly, near the costochondral junctions, the are replaced by the external intercostal membrane. These muscles also play a role in stabilizing the during body movements, helping to maintain structural integrity.

Internal and Innermost Intercostal Muscles

The internal intercostal muscles form the intermediate layer of the intercostal muscle group, lying deep to the external intercostals and superficial to the innermost layer. They originate from the floor of the costal groove on the inferior surface of the rib above, specifically from its lateral edge, and insert onto the superior border of the rib immediately below. Their muscle fibers run obliquely in a downward, backward, and lateral direction, perpendicular to those of the external intercostals. This layer spans the intercostal spaces from the costochondral junctions anteriorly to the angles of the ribs posteriorly, though it thins out anteriorly to become more membranous near the . The innermost intercostal muscles constitute the deepest layer, positioned medial to the internal intercostals and separated from them by the . They originate from the inner or medial surface of the costal groove on the inferior aspect of the above and insert onto the superior border of the below, with fibers oriented in a similar downward and posterior direction, parallel to those of the internal intercostals. This layer is thinner and less muscular overall compared to the internal intercostals, appearing more membranous in certain regions, particularly posteriorly where it contributes to the intercostal membrane. The innermost intercostals are present in the intercostal spaces, though often incomplete or absent in the uppermost ones; anteriorly, they blend with the , while posteriorly and inferiorly, they may connect with the subcostal muscles.

Vascularization and Innervation

Blood Supply

The intercostal muscles are supplied by a dual arterial network consisting of posterior and anterior . The posterior intercostal arteries provide the primary supply to the posterior aspects of the intercostal spaces. The first and second posterior intercostal arteries originate from the superior intercostal artery, a branch of the costocervical trunk, while the third through eleventh arise directly from the descending . These arteries course along the inferior borders of the within the costal grooves, supplying the intercostal muscles, pleura, and overlying . The anterior intercostal arteries supply the anterior portions of the upper s. For spaces 1 through 6, these arteries arise from the , while spaces 7 through 9 receive branches from the musculophrenic artery, a terminal division of the ; the lowest two spaces (10 and 11) typically lack dedicated anterior intercostal arteries but receive collateral supply. Each features anastomoses between the anterior and posterior near the midline, forming a collateral circulation that enhances vascular redundancy. Venous drainage parallels the arterial supply. The posterior intercostal veins drain into the on the right and the hemiazygos or accessory hemiazygos veins on the left, ultimately connecting to the . The anterior intercostal veins converge into the internal thoracic vein, which joins the . These veins accompany the arteries in the intercostal spaces, facilitating efficient return of deoxygenated blood from the muscles. Within each , the vascular structures form part of the located in the costal groove along the inferior margin, ordered from superior to inferior as , , and (mnemonic: VAN). This arrangement protects the vessels during procedures involving the . Anatomical variations may include aberrant origins of posterior or atypical anastomotic patterns, which can influence surgical approaches.

Nerve Supply

The , which provide motor and sensory innervation to the intercostal muscles, originate from the ventral rami of the thoracic spinal nerves T1 through T11, while the arises from the of T12. These nerves emerge shortly after the spinal nerves exit the intervertebral foramina and give off rami communicantes to the before continuing anteriorly. Each intercostal nerve enters its corresponding posteriorly, passing between the parietal pleura and the posterior , before traveling forward within the costal groove along the inferior border of the . In this groove, the nerve runs deepest in the (VAN: vein superiorly, artery in the middle, nerve inferiorly), positioned between the internal intercostal muscle superiorly and the inferiorly, protected by the above. The follows a similar path but inferior to the 12th , without entering a typical . The primary distribution of each intercostal nerve includes muscular branches that supply all three layers of the intercostal muscles (external, internal, and innermost) within its space, as well as adjacent structures such as the subcostal muscles, serratus posterior superior, and transversus thoracis. Collateral branches arise from the nerve stem to run along the superior border of the inferior rib, innervating the intercostal muscles, parietal pleura, and within the same space. Additionally, lateral cutaneous branches pierce the midway along the to supply the skin of the lateral , while anterior cutaneous branches emerge near the to innervate the anterior thoracic ; these sensory components do not directly supply the muscles but provide proprioceptive feedback. Notable exceptions occur at the extremes of the thoracic levels: the first intercostal nerve (T1) is small and atypical, with its main contribution joining the , leaving only a minor branch to supply the first muscles. The lower intercostal nerves (T7–T11), transitioning into , extend beyond the to communicate with the and supply muscles, while the (T12) similarly anastomoses with the first and innervates the lowermost intercostal and subcostal muscles before piercing the external oblique .

Function

Role in Breathing

The intercostal muscles play a crucial role in the mechanics of by facilitating changes in thoracic volume through movements. During , the contract to elevate the , primarily through two distinct motions: the "bucket-handle" movement, which increases the transverse diameter of the by outward rotation of the around their costovertebral joints, and the "pump-handle" movement, which enhances the anteroposterior diameter by upward tilting of the anterior rib ends at the costochondral junctions. This elevation expands the , reducing and drawing air into the lungs. In quiet , the external intercostals contribute approximately 30% to the increase in the upright position, complementing the diaphragm's dominant role. For expiration, the internal and innermost intercostal muscles to depress the , reversing the inspiratory motions and decreasing thoracic to expel air. This action is particularly important during forced expiration, such as in exercise or coughing, where it aids in generating higher expiratory pressures. In contrast, quiet expiration is largely passive, relying on the of the lungs and chest wall rather than active intercostal contraction. The intercostal muscles coordinate closely with the to optimize respiratory efficiency. As the contracts and descends during , the external intercostals simultaneously elevate the , amplifying the overall increase in thoracic dimensions and ensuring balanced expansion of the . During expiration, relaxation of the external intercostals allows passive recoil, while internal intercostals engage as needed for active efforts. Biomechanically, rib elevation by the external intercostals during deep can increase the transverse and anteroposterior thoracic diameters substantially, contributing to an approximate 100-150% rise in overall thoracic volume from to total , depending on individual factors.

Additional Functions

Beyond their primary role in respiration, the intercostal muscles contribute to trunk stabilization by maintaining the integrity of the rib cage during activities that generate increased intra-abdominal or intrathoracic pressure, such as coughing, sneezing, and the . During coughing and sneezing, the internal intercostal muscles contract to facilitate forced expiration, helping to stabilize the against the sudden pressure changes and prevent rib displacement or injury. In the , which involves forced expiration against a closed , the intercostal muscles, particularly the internal ones, work to compress the , supporting overall rigidity and aiding in pressure equalization. The intercostal muscles also serve accessory functions in non-respiratory activities requiring precise control of thoracic volume, including speech, , and exercise. In speech and , the assist in fine-tuning expansion to regulate and sustain , allowing for controlled and expiration beyond quiet demands. During exercise, these muscles enhance thoracic expansion to meet increased ventilatory needs, coordinating with the to optimize oxygen intake without compromising efficiency. In postural control, the internal intercostal muscles play a key role in facilitating lateral flexion and of the through selective . of the internal intercostals on one side of the depresses the , contributing to ipsilateral lateral flexion and ipsilateral , which helps maintain and positioning during . This postural function is evident in activities involving , where electromyographic studies show tonic activity in the intercostal muscles to stabilize the against gravitational and inertial forces. The interplay between these postural and respiratory roles allows the intercostals to adapt their activation patterns based on the dominant task. Furthermore, the intercostal muscles interact with abdominal muscles to enable forced expiration in non-pulmonary activities like and . During these processes, the internal intercostals contract in coordination with the muscles to increase intra-abdominal pressure, facilitating expulsion while stabilizing the . This synergy is crucial for the expulsive phase of , where intercostal activation supports the rapid pressure buildup required for emetic force. In , similar coordination aids in straining by enhancing thoracic compression alongside abdominal effort.

Clinical Significance

Common Injuries and Conditions

Intercostal muscle is a frequent injury among athletes and individuals experiencing , often resulting from sudden twisting motions, overuse during repetitive activities like pitching in , or direct impact to the chest wall. This condition involves tearing or stretching of the intercostal muscle fibers, leading to sharp, localized pain between the that intensifies with deep , coughing, twisting, or arm movements. In cases associated with rib fractures, the strain exacerbates tenderness and may contribute to altered breathing patterns, such as shallow respirations, due to pain avoidance. Overuse in sports, such as in players, can present with similar symptoms including intercostal formation, highlighting the vulnerability of these muscles to repetitive stress. Intercostal neuralgia arises from irritation or damage to the , which originate from the anterior rami of thoracic spinal nerves T1 through T11 and provide motor and sensory innervation to the intercostal muscles and overlying . This leads to radiating along the affected 's distribution, often described as burning, shooting, or stabbing sensations in the chest, , or upper , which can mimic cardiac or pulmonary conditions due to its referral pattern. Common etiologies include viral infections like herpes zoster, which reactivates in the dorsal root ganglia and inflames the intercostal nerves, or mechanical compression from rib fractures, tumors, or post-surgical scarring. The pain may persist or become chronic, significantly impairing mobility and respiratory effort. Myofascial pain syndrome involving the intercostal muscles manifests as discrete trigger points—hyperirritable nodules within taut muscle bands—that elicit localized tenderness upon and can refer pain to adjacent areas like the chest wall or upper back. These trigger points often develop secondary to herpes zoster infection, where post-viral in the intercostal region promotes myofascial dysfunction, or following procedures that disrupt muscle integrity. Patients typically experience restricted expansion, muscle stiffness, and exacerbated discomfort with breathing or posture changes, distinguishing it from purely . In post- cases, the syndrome contributes to chronic chest wall pain, with trigger points responding to targeted interventions but often requiring identification through . Flail chest occurs when multiple consecutive ribs (typically three or more) sustain fractures at two or more points each, creating a detached, unstable of the chest wall that disrupts the intercostal muscles' attachment and normal mechanics. This leads to paradoxical , where the flail moves inward during and outward during expiration, opposite to the rest of the , due to negative intrathoracic pressure imbalances. The condition, often resulting from high-impact like motor vehicle accidents, carries high morbidity, with mortality rates ranging from 10% to 40% primarily from associated , , or . Intercostal muscle detachment in flail chest impairs ventilatory efficiency, increasing the risk of acute respiratory distress and prolonged needs.

Diagnostic and Therapeutic Procedures

Diagnosis of intercostal muscle issues typically begins with a thorough medical history and physical examination, focusing on the onset, location, and nature of pain, as well as any precipitating activities or trauma. During the physical exam, palpation of the intercostal spaces assesses for tenderness, while respiratory maneuvers evaluate pain provocation during breathing or coughing; for intercostal neuralgia, specific signs like Schepelmann’s sign (increased pain on lateral bending toward the affected side) or dermatomal patterns of sharp, burning pain with paresthesia may be elicited. Imaging modalities are employed to rule out associated injuries: X-rays or CT scans detect rib fractures or other bony abnormalities, while MRI provides detailed visualization of soft tissue strains, edema, or tears in the intercostal muscles. In cases of suspected neuralgia, diagnostic intercostal nerve blocks with local anesthetics can confirm the pain source by providing temporary relief, guiding further management. Therapeutic approaches for intercostal muscle strains and related conditions prioritize conservative measures initially. Rest to avoid aggravating activities, application of or , and nonsteroidal drugs (NSAIDs) like ibuprofen help reduce pain and inflammation in the acute phase. , including breathing exercises and gentle stretching, promotes recovery by improving muscle strength and respiratory function without invasive intervention. For persistent pain, particularly from intercostal , intercostal nerve blocks involving injection of local anesthetics such as bupivacaine, often combined with corticosteroids, provide targeted relief by interrupting pain signals along the affected nerves. In severe cases like involving multiple fractures that destabilize the intercostal muscles, surgical repair through rib plating stabilizes the chest wall, reducing paradoxical motion and improving ventilation; this approach has been shown to shorten ICU stays and lower rates compared to conservative care. Certain procedures carry risks to the intercostal muscles and adjacent structures due to the neurovascular bundle's location inferior to each . Thoracentesis or insertion can inadvertently damage intercostal muscles, nerves, or vessels if the needle or tube is placed too high in the interspace, potentially causing bleeding, , or . Prophylactic measures include guidance to visualize and avoid the bundle, inserting instruments over the rib's superior border, and confirming placement with post-procedure imaging. As of 2025, the has released best practices guidelines for managing chest wall injuries, emphasizing early surgical stabilization for to reduce mortality risks up to 36% in severe cases. Emerging techniques enhance procedural safety and efficacy in managing intercostal issues. Ultrasound-guided intercostal injections, including blocks, improve precision by allowing real-time visualization of the target area, thereby reducing complications like vascular puncture or compared to landmark-based methods. Recent advances also include ultrasound-guided percutaneous cryoneurolysis for intercostal , which decreases pain and use while improving volume, and peripheral stimulation for refractory cases. Muscle-sparing surgical approaches for rib fractures further support long-term and mobility outcomes. This approach is particularly valuable for repeated interventions in scenarios, minimizing tissue trauma to the intercostal muscles.

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