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Accessory breast

Accessory breast tissue, also known as polymastia or supernumerary breast, is a congenital anomaly characterized by the presence of ectopic glandular breast tissue outside the normal pectoral region, resulting from the incomplete regression of the embryonic mammary ridge, or "milk line," which extends bilaterally from the axilla to the inguinal area.^[1] This condition manifests as additional breast components, which may include glandular tissue, nipple, and areola, and is classified into eight types based on the components present, ranging from complete breast structures to isolated glandular tissue.^[1] The embryological origin traces back to the development of the mammary ridge in the early embryo, where typically only the thoracic portions persist to form the normal breasts, while the remaining segments regress; failure of this regression leads to accessory tissue formation, with no known specific genetic or environmental triggers beyond this developmental process.^[1] Prevalence varies by sex and ethnicity, affecting approximately 2-6% of females and 1-3% of males worldwide, with higher rates reported in Asian populations (up to 5% in Japanese women) compared to Caucasians (around 0.6%); about one-third of cases involve multiple accessory sites.^[1] ^[2] The most common location is the axilla, accounting for 60-96% of cases and often bilateral, though rarer ectopic sites include the chest wall, abdomen, back, thigh, or even the face; accessory tissue is frequently unnoticed until hormonal changes during puberty, pregnancy, or lactation cause enlargement and symptoms.^[2] ^[1] Clinically, accessory breast tissue is often asymptomatic but can present with axillary swelling, tenderness, pain (especially premenstrually), restricted arm movement, cosmetic concerns, or milk secretion during lactation; in some cases, it may be associated with supernumerary nipples (polythelia), which occur along the same milk line.^[2] Complications are uncommon but include the development of benign conditions like fibroadenoma or, rarely, malignant transformation into accessory breast cancer, which comprises 0.3-0.6% of all breast carcinomas and requires vigilant monitoring similar to primary breast tissue.^[2] Diagnosis typically involves physical examination, with imaging modalities such as ultrasonography (sensitivity ~69%), mammography, or MRI to confirm glandular nature and rule out pathology; histopathological examination post-excision reveals simple breast tissue in most cases (~83%).^[2] Management is conservative for asymptomatic cases, with no intervention required, as the tissue functions similarly to normal breast and may even support lactation; however, surgical excision—via direct incision, liposuction, or a combination—is recommended for symptomatic relief, cosmetic improvement, or suspicion of malignancy, yielding high satisfaction rates and minimal complications (e.g., ~54% complication-free postoperatively).^[1] ^[2] Early detection and awareness are emphasized, particularly in women undergoing routine breast screening, to differentiate accessory tissue from other axillary pathologies like lymphadenopathy.^[2]

Anatomy and Embryology

Embryological Origin

During embryonic development, the mammary glands originate from the mammary ridge, also known as the milk line, which forms as bilateral ectodermal thickenings along the ventral surface of the embryo. This structure appears between the 4th and 6th weeks of gestation, extending continuously from the axilla to the inguinal region, and arises from proliferation of epithelial cells in the epidermis of the thoracic region.^[3] In normal development, the mammary ridge undergoes regression, with most segments atrophying through a process involving apoptosis, leaving only paired solid epithelial masses in the pectoral region that develop into the primary thoracic mammary buds. The primary mammary buds then invaginate into the underlying mesenchyme by the end of the first trimester. Failure of this complete regression results in persistent ectopic mammary tissue along the original milk line path.^[3]^[4] The concept of the mammary ridge as a developmental precursor to breast tissue was first described in anatomical observations during the late 19th century, with Schultze noting its presence in 1892 and Schmidt naming it the "mammary band" in 1896 based on studies of human embryos. These early insights laid the foundation for understanding accessory breast tissue as remnants of incomplete ridge involution.

Anatomical Variations

Accessory breast tissue, a congenital anomaly resulting from the persistence of embryonic mammary ridge remnants, most commonly develops along the milk line extending from the axilla to the groin.^[5] The axilla represents the primary site, occurring in 60-70% of cases, with additional locations including the inframammary fold, lower abdomen, groin, and medial thigh.^[6]^[7] Other rarer sites outside the typical milk line pathway, such as the face, neck, or extremities, have been documented but are exceptional.^[5] The composition of accessory breast tissue varies widely; it may encompass glandular parenchyma with ducts and lobules, a nipple, and areola in complete forms, or limited to isolated glandular elements, nipple alone (polythelia), areola (polythelia areolaris), or even non-glandular subcutaneous fat and muscle without mammary features.^[8]^[9] Classifications, such as Kajava's system, delineate these as complete (Class I: full breast with glandular tissue, nipple, and areola) versus incomplete variants lacking one or more components, with glandular-inclusive forms being the primary focus for clinical relevance.^[10] Bilateral involvement occurs in approximately one-third of cases, and multiple ectopic sites are rare but possible, potentially leading to symmetric or asymmetric presentations along the milk line.^[10]^[9] Accurate differentiation from mimicking conditions is crucial; unlike lipomas, which consist solely of adipose tissue without fibroglandular elements, accessory breast contains mammary-specific structures identifiable via imaging or histology.^[8] Similarly, hidradenitis suppurativa involves inflammatory apocrine gland changes without glandular breast tissue, distinguishing it through absence of hormonal responsiveness and presence of suppuration.^[5]^[8]

Epidemiology

Prevalence and Incidence

Accessory breast tissue, also known as polymastia, occurs in up to 6% of the population based on clinical, autopsy, and imaging studies.^[10] This prevalence is supported by multiple investigations, including those examining routine clinical examinations where rates range from 1% to 5%, and imaging cohorts that report figures approaching 6%.^[11]^[12] The condition is more prevalent in women, with incidence rates of 2-6%, compared to 1-3% in men.^[12]^[11] Detection often occurs during periods of hormonal change, such as puberty or pregnancy, when the tissue may enlarge and become noticeable.^[12]^[13] Many cases remain undetected due to their asymptomatic nature, leading to potential underreporting in the general population.^[14] This underdiagnosis is particularly common in individuals without routine medical imaging or examinations, as the tissue may mimic normal anatomical variations until symptomatic.^[5]

Demographic Patterns

Accessory breast tissue, also known as polymastia, shows notable ethnic variations in prevalence. Rates are highest among Asian populations, particularly Japanese individuals, where occurrence can reach 5-6%, while lower rates of 0.6-2% are observed in Caucasian populations.^[1]^[15]^[8] Gender differences influence the detection and presentation of accessory breast tissue, which occurs in both males and females but is more commonly identified in women due to hormonal changes during puberty, pregnancy, and lactation that cause enlargement. The condition is approximately twice as common in females as in males (male-to-female ratio of ~1:2).^[11]^[2] Age-related patterns typically involve incidental detection in adulthood, with increased visibility during reproductive years when estrogen-driven growth highlights the tissue. Presentation often aligns with puberty or pregnancy, peaking in women aged 20-40 years.^[16]^[17] Geographic and familial clustering of accessory breast tissue is uncommon, though rare genetic links, such as pathogenic variants in the FANCC gene, have been associated with familial cases across generations. No strong inheritance patterns, such as autosomal dominant transmission, have been firmly established, and distributions primarily follow ethnic rather than geographic lines.^[18]^[19]

Clinical Presentation

Common Manifestations

Accessory breast tissue typically presents as visible or palpable lumps along the embryonic milk line, which extends from the axilla to the groin, often resembling normal breast tissue in consistency and texture.^[1] These lumps are most frequently located in the axillary region, accounting for the majority of cases.^[2] In approximately 5-15% of cases, accessory breast tissue includes a nipple and/or areola complex, which may contribute to noticeable asymmetry in the affected area.^[2] The tissue often undergoes enlargement or becomes more prominent during periods of hormonal fluctuation, such as puberty, pregnancy, or lactation, mirroring the developmental responses of primary breast tissue.^[1]^[12] Many instances of accessory breast tissue are discovered incidentally during routine physical examinations, as the condition is frequently asymptomatic and overlooked until hormonal changes highlight its presence.^[5]

Associated Symptoms

Accessory breast tissue, also known as polymastia, is frequently asymptomatic but can cause various discomforts, particularly when influenced by hormonal fluctuations. Pain and tenderness are among the most common symptoms, often presenting as cyclical discomfort that intensifies during premenstrual or menstrual phases, puberty, pregnancy, or lactation due to the tissue's responsiveness to estrogen and progesterone.^[1] In a study of 52 patients, approximately 23% experienced pain in the accessory mass specifically during these periods, while daily axillary discomfort exacerbated by hormonal cycles has been reported in case presentations lasting several years.^[2] During lactation, engorgement of the tissue may occur, leading to further tenderness in about 6% of affected individuals.^[2] Cosmetic concerns significantly impact those with accessory breast, often manifesting as visible asymmetry or bulging under clothing, particularly in axillary locations, which can cause self-consciousness and affect clothing choices. In the same cohort of 52 patients, over 73% reported uneasiness related to the mass's position, leading to diminished self-confidence and psychological distress such as anxiety.^[2] These aesthetic issues may also result in irritation from friction with garments, contributing to ongoing discomfort.^[1] Functional limitations arise primarily in axillary cases, where the tissue can restrict arm or shoulder movement, causing heaviness or vague discomfort during daily activities. Local skin irritation and potential for secondary issues like sweating-induced moisture in the area may exacerbate these problems, though direct infection risks are uncommon.^[1] Rare acute symptoms include galactorrhea, characterized by inappropriate milk secretion from the accessory nipple, often postpartum or in response to hormonal stimulation, as seen in adolescent and adult cases.^[10] Additionally, mastitis, including non-lactational or granulomatous forms, can develop in functional accessory tissue, presenting as inflammatory swelling and pain, though such occurrences are infrequent and challenging to diagnose.^[20]

Pathophysiology

Developmental Mechanisms

The development of accessory breast tissue, also known as polymastia, arises primarily from the incomplete regression of the embryonic mammary ridge, or milk line, which forms during the fourth to sixth weeks of gestation and extends from the axilla to the inguinal region.^[21] In typical human embryogenesis, this ridge involutes by the seventh to tenth weeks, leaving only the pectoral pair of mammary primordia to develop into functional breasts, but persistence of additional segments along the line results in ectopic mammary tissue.^[21] Genetic factors, such as an autosomal dominant inheritance pattern with variable expressivity, are implicated in preventing normal regression of these embryonal ridges in utero.^[22] At the cellular level, the failure of programmed cell death, or apoptosis, in the extra mammary primordia is a key mechanism underlying ridge persistence. During normal gestation, apoptotic processes drive the involution of superfluous ridge segments, eliminating primordial breast cell clusters; disruption of this apoptosis leads to the retention and potential differentiation of ectopic glandular tissue.^[8] Animal models, such as those in mice, provide valuable insights into these human embryological processes, as the formation and selective regression of mammary lines are conserved across mammals. In mice, the embryonic mammary line forms multiple placodes along the ventral axis around embryonic day 10.5, with all but the thoracic pairs undergoing regression through similar apoptotic mechanisms, mirroring the developmental anomalies seen in human accessory breast tissue.^[23] These models have been instrumental in elucidating the molecular signaling pathways, including Wnt and FGF pathways, that regulate ridge specification and involution.^[24]

Histological Features

Accessory breast tissue, also known as supernumerary breast tissue or polymastia, exhibits a microscopic structure that closely resembles that of normal breast tissue, consisting of glandular elements including ducts and lobules embedded within fibrous stroma and adipose tissue.^[8] The ductal structures are lined by epithelial cells, often forming acini that may show secretory activity, particularly during hormonal influences such as pregnancy or lactation, with surrounding stroma providing structural support similar to the pectoral breast.^[13] In many cases, the tissue includes mature adipose components interspersed among the glandular elements, contributing to its overall composition.^[5] Histological variations in accessory breast tissue depend on its developmental class, as described by Kajava's 1915 classification system; for instance, class I features complete glandular tissue with well-formed lobules and ducts, while class IV, the most common form, presents only isolated glandular foci without nipple or areola, potentially showing incomplete or rudimentary acinar development.^[5] Some specimens display fibrocystic changes, including cyst formation or apocrine metaplasia, but these are benign and mirror physiological alterations in normal breast tissue.^[13] Full acinar structures with secretory epithelium are observed in hormonally stimulated cases, whereas others may lack organized lobular architecture due to ectopic location along the milk line.^[8] Biopsy findings typically confirm benign mammary glandular tissue, with immunohistochemical staining positive for markers such as GATA3, mammaglobin, and BRST-2, aiding in differentiation from other adnexal structures.^[8] Malignant changes, though rare, can occur and include infiltrating ductal carcinoma, but the tissue remains benign in the absence of such alterations, showing no atypical proliferation unless pathologically induced.^[5] This ectopic glandular tissue arises from persistent remnants of the embryonic milk line, but its mature structure parallels that of the primary breast.^[5]

Diagnosis

Clinical Assessment

Clinical assessment of accessory breast tissue begins with recognizing scenarios where suspicion arises, such as during pregnancy or when patients present with cosmetic concerns like visible axillary lumps, which are common manifestations of this condition.^[12] Suspected accessory breast is also warranted in cases of cyclical discomfort or swelling along the milk line, particularly during periods of hormonal fluctuation like puberty, pregnancy, or menstruation.^[14] History taking is essential and should include inquiries into family history, as accessory breast tissue may exhibit an autosomal-dominant inheritance pattern with incomplete penetrance, though most cases are sporadic.^[5] Clinicians should probe for symptoms such as tenderness, pain, or swelling that correlate with hormonal changes, including menstrual cycles, puberty, or pregnancy, as well as any functional issues like restricted arm movement or irritation from clothing.^[1] Additional details on the onset and progression of any noticed masses or skin changes help contextualize the presentation. The physical examination involves systematic palpation along the embryonic milk line, extending from the axilla to the inguinal region, to identify any soft tissue swellings, glandular masses, nipples, or areolae that deviate from normal anatomy.^[12] Examination should be bilateral, as accessory tissue is often symmetric, and focus on characteristics like mobility, tenderness, and relation to hormonal influences, with careful documentation using classifications such as Kajava's to describe the extent of glandular, nipple, or areolar components.^[1] Differential diagnosis requires distinguishing accessory breast from other axillary or thoracic masses, including enlarged lymph nodes, lipomas, hernias, sebaceous cysts, or hidradenitis suppurativa, through careful correlation of history and exam findings.^[14] Neoplastic processes, such as tumors, must also be considered and ruled out based on atypical features like rapid growth or fixation, emphasizing the need for a thorough clinical evaluation to guide further steps.^[1]

Imaging and Confirmation

Ultrasound serves as the first-line imaging modality for evaluating suspected accessory breast tissue, particularly in cases of palpable axillary masses, due to its ability to characterize soft tissue without radiation exposure. It typically reveals a heterogeneous echotexture resembling normal breast parenchyma, with interspersed hypoechoic fibroglandular elements and hyperechoic fat lobules, confirming the glandular nature of the tissue.^[5]^[25] This modality is especially useful in younger patients or during pregnancy, where it demonstrates high sensitivity—approaching 100% negative predictive value—for distinguishing benign accessory tissue from other pathologies in symptomatic presentations.^[26] However, its overall sensitivity for detecting asymptomatic or incidental accessory breast tissue is moderate, reported at approximately 69% (95% CI: 54.9–81.3%), often necessitating correlation with clinical findings.^[2] Mammography is employed as a complementary tool, particularly in adult women over 30 years or when malignancy is suspected, to assess for dense fibroglandular densities discontinuous from the main breast or focal asymmetries in the axilla. It may identify accessory tissue as a patch of glandular elements interspersed with fat, but its utility is limited in non-dense breasts or obese patients, where ultrasound correlation is essential.^[5]^[27] For more comprehensive evaluation, especially in dense tissue or equivocal cases, magnetic resonance imaging (MRI) is recommended, revealing signal intensity and enhancement patterns akin to normal breast tissue, such as ill-defined subcutaneous masses with homogeneous or variable contrast uptake.^[5]^[28] Features consistent with benign accessory tissue on these modalities can be classified as BI-RADS category 2, warranting only clinical follow-up without further intervention.^[29] If imaging reveals atypical features, such as irregular masses, microcalcifications, or suspicious enhancement, confirmatory biopsy is indicated to rule out malignancy. Fine-needle aspiration or ultrasound-guided core needle biopsy is preferred for its minimally invasive nature and high diagnostic accuracy in sampling glandular tissue, providing histopathological confirmation of accessory breast elements adjacent to normal ducts.^[5]^[30] This approach is particularly crucial in symptomatic cases or when incidental findings prompt concern for rare associated carcinomas.^[31]

Management and Treatment

Conservative Approaches

For asymptomatic cases of accessory breast tissue, often referred to as polymastia, observation is the preferred approach, involving regular self-examinations to monitor for any changes in size, tenderness, or other developments.^[25]^[17] This watchful waiting strategy is suitable for small, non-palpable masses without associated symptoms, as treatment is generally unnecessary unless complications arise.^[32] Supportive care plays a key role in managing mild symptoms such as pain or discomfort, particularly in the axillary region. Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, can provide relief from cyclical tenderness, while well-fitted supportive bras or garments help reduce physical strain and improve comfort during daily activities or movement.^[33]^[34] Warm or cold compresses applied intermittently may also alleviate localized swelling or pain, especially during lactation when accessory tissue can become engorged.^[14] In such instances, simple analgesics and ice packs are recommended, with cessation of breastfeeding to promote regression without further intervention.^[35] Hormonal management may address cyclical pain linked to menstrual fluctuations, as accessory breast tissue responds similarly to normal mammary glands. Low-dose oral contraceptive pills can help stabilize hormone levels for estrogen- or progesterone-driven symptoms, though evidence is mixed and consultation with a provider is advised.^[36]^[37]^[38] Non-invasive options, such as cryolipolysis (e.g., CoolSculpting) or deoxycholic acid injections (e.g., Kybella), may be considered for cosmetic reduction of predominantly fatty accessory tissue in cases without significant glandular components.^[39] Counseling is essential for patients experiencing psychological distress, such as anxiety or reduced self-esteem due to cosmetic concerns from visible axillary tissue. Healthcare providers should offer guidance on body image, including techniques for cosmetic camouflage through clothing choices that minimize prominence, alongside referrals for psychological support to address emotional impacts.^[40]^[32] This holistic approach helps improve quality of life for those opting against more invasive options.^[41]

Surgical Interventions

Surgical interventions for accessory breast tissue, also known as polymastia, are primarily indicated for cases involving persistent pain, recurrent infections, or patient preference for cosmetic improvement.^[5] These procedures aim to remove excess glandular, fatty, or nipple tissue while minimizing disruption to surrounding structures, often confirmed via prior clinical or imaging diagnosis of the tissue type.^[39] Excision is the standard surgical approach for symptomatic accessory breast tissue, involving the removal of glandular components and any associated nipples through a curvilinear incision placed within the axillary crease to optimize cosmesis.^[39] The procedure utilizes instruments such as curved Mayo scissors and electrocautery for precise dissection, with a small ellipse of skin excised if necessary to address laxity; it is performed under local or general anesthesia, with careful consideration to avoid impairing lactation function in cases where the tissue is active.^[39] A Jackson-Pratt drain is typically inserted to prevent seroma formation, and the wound is closed in layers using absorbable sutures.^[39] Liposuction serves as an alternative or adjunct for predominantly fatty accessory tissue, employing small cannulas (3-4 mm) under tumescent anesthesia to aspirate excess fat in a fanning pattern, thereby contouring the area without extensive scarring.^[39] This method is suitable for milder cases lacking significant glandular elements or skin laxity, with an average of 131-208 mL of fat removed per axilla depending on the extent.^[39] Combined liposuction and excision may be used for moderate to severe presentations involving both fat and glandular tissue, enhancing outcomes while reducing postoperative bulk.^[39] Postoperative care emphasizes infection prevention through meticulous wound hygiene, including gentle cleansing with soap and water, avoidance of soaking the site, and prophylactic antibiotics if indicated.^[42] Patients are advised to wear compression garments to minimize swelling and support healing, with drains removed within 1-2 weeks once output decreases; scar minimization involves sun protection, topical silicone gels, and massage starting after initial healing to reduce hypertrophy.^[39]^[43] Light arm exercises are encouraged early to prevent stiffness, with full recovery typically achieved in 4-6 weeks.^[44]

Complications and Prognosis

Potential Risks

Accessory breast tissue, owing to its histological similarity to normal breast tissue, carries a rare risk of malignant transformation, with breast cancer developing in the glandular components at an incidence of less than 1% based on reported cases.^[45] Primary carcinomas, such as invasive ductal carcinoma, have been documented in ectopic sites like the axilla, often presenting as palpable lumps and requiring inclusion in differential diagnoses for tumors along the milk line.^[46] This low but established risk underscores the potential for neoplastic changes in untreated glandular tissue.^[5] Benign conditions such as fibroadenoma and fat necrosis can also develop in accessory breast tissue, similar to normal breast tissue.^[5] Infections represent another concern for accessory breast tissue with functional glandular elements, particularly during periods of lactation, where mastitis or abscess formation can occur.^[20] Granulomatous mastitis, a chronic inflammatory condition, has been reported in axillary accessory tissue, manifesting as painful masses or erythema that may mimic other pathologies if untreated.^[47] Abscesses in this tissue can develop secondary to bacterial entry, leading to localized pus collections that complicate the clinical picture.^[20] Beyond infectious and oncogenic risks, untreated accessory breast tissue may contribute to chronic pain, especially with hormonal fluctuations causing swelling or tenderness, which in severe cases can limit arm mobility.^[48] This persistent discomfort often leads to psychological distress, including anxiety over appearance or fear of underlying disease, particularly in adolescents or during reproductive years.^[2] Given these potential risks, screening recommendations for individuals with confirmed functional accessory breast tissue advocate for its inclusion in routine breast examinations, such as mammography and ultrasound, to monitor for malignancy or other changes akin to standard breast tissue protocols.^[12] Early detection through such integrated screening is emphasized to mitigate complications from ectopic sites.^[25]

Long-Term Outcomes

Accessory breast tissue, also known as polymastia, typically follows a benign course, with most cases remaining stable throughout life in the absence of intervention, particularly when asymptomatic.^[5] This stability is attributed to its congenital nature, though the tissue may undergo physiological changes in response to hormonal fluctuations, such as enlargement or tenderness during puberty, pregnancy, lactation, or menopause.^[5] Untreated asymptomatic instances rarely require management and do not significantly impact health over the long term.^[49] Following treatment, outcomes are generally favorable, with low rates of recurrence reported in short- to medium-term follow-up periods. Surgical excision, the primary intervention for symptomatic cases, effectively alleviates discomfort, cosmetic concerns, and functional limitations, leading to improved quality of life in affected individuals.^[49] For example, in cohorts undergoing excision, patients experienced relief from pain and anxiety, with high satisfaction and minimal complications such as scarring or swelling that resolved conservatively.^[39] Conservative approaches, when appropriate, also support stable long-term results without progression in benign presentations.^[5] Monitoring recommendations emphasize inclusion of accessory breast tissue in standard breast cancer screening protocols, with periodic clinical assessments and imaging such as ultrasound to detect any changes, mirroring protocols for ectopic glandular structures.^[49]^[12] Despite these insights, research gaps persist, including limited long-term studies on untreated cohorts, which hinder comprehensive understanding of lifelong stability and optimal surveillance strategies beyond short follow-up durations of 6-12 months.^[39] Larger, prospective investigations are needed to address recurrence risks and hormonal influences over decades.^[49]

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Aug 22, 2023 · There are nonsurgical options for its removal, such as CoolSculpting and Kybella, and surgical options such as liposuction, BodyTite liposuction, and excision.
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Postoperative Wound Infections - StatPearls - NCBI Bookshelf
Utilizing appropriate scrubbing techniques and double gloving can help reduce the incidence of postoperative infections.[24] The World Health Organization (WHO) ...
[45]
Axillary Breast Removal Gets Rid Of Unwanted Bulkiness
Your axillary breast tissue can be safely removed with surgery. This can be done with liposuction, if there is little correction required, or exision (removing ...Unique Point: Hidden Scars · Recovering From Your Surgery · Related Articles<|control11|><|separator|>
[46]
Axillary Breast Surgery Recovery - Timeline, Diet, & Lifestyle
Wear Compression Garments: The surgeon may recommend wearing compression garments after surgery to help reduce swelling and provide support to the surgical site ...
[47]
A rare case of primary carcinoma of axillary accessory breast tissue
Oct 20, 2021 · Carcinomas of primary accessory breast tissue are rare, comprising 0.3–0.6% of all breast cancers and occur most commonly in the axilla. We ...
[48]
Invasive carcinoma in accessory axillary breast tissue: A case report
Breast cancer in accessory breast tissue is very rare. The incidence is around 6%. Most common pathology is invasive ductal carcinoma (50–75%). The most common ...<|control11|><|separator|>
[49]
A Rare Case of Granulomatous Mastitis in the Accessory Axillary ...
Granulomatous mastitis (GM) is an uncommon chronic inflammatory disease of the breast that presents with symptoms such as breast mass, abscess, erythema, ...
[50]
Symptoms of Ectopic Axillary Breast Tissue and Complications to ...
The aim of this study was to describe the association between symptoms of ectopic breast tissue and choice of treatment, and related complications.
[51]
Axillary breast: our limited experience of surgical excision - PMC - NIH
Jul 15, 2025 · However, it may also cause psychological distress during adolescence, pain, restricted arm movement, cosmetic concerns, anxiety related to ...
[52]
Is Accessory Breast Tissue Harmful? All You Need To Know
Nov 29, 2022 · There is still much debate on the potential harm associated with the condition. Some research has suggested an increase in the incidence of cancer related to ...Missing: counseling cosmetic camouflage
[53]
A Study of Evaluation and Management of Rare Congenital Breast ...
Oct 1, 2016 · The incidence of Polymastia (supranumerary breasts) and polythelia (supranumerary nipples) is around 2-6% among the female population [6].