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Foraminotomy

Foraminotomy is a surgical that widens the —the bony opening in the through which roots exit—to relieve compression on the nerves caused by conditions such as foraminal , spurs, herniated discs, or thickening. This decompression aims to alleviate symptoms including radiating pain, numbness, tingling, and in the arms, legs, or other affected areas, typically resulting from degenerative changes in the , thoracic, or . The , which originated in the mid-20th century as part of the evolution of techniques, is indicated when conservative treatments like , medications, or injections fail to provide relief, and it preserves spinal motion without requiring fusion in many cases. The surgery is usually performed under general anesthesia, with the patient positioned face down or seated, and involves a small incision in the back or neck to access the affected vertebra. Surgeons use specialized tools, often guided by X-ray or microscopic visualization, to remove portions of bone, disc material, or soft tissue obstructing the foramen, thereby creating more space for the nerve root. It may be combined with related techniques such as laminotomy (partial removal of the lamina) or discectomy if additional decompression is needed, and modern approaches increasingly favor minimally invasive or endoscopic methods to reduce tissue damage and speed recovery. Preparation typically includes imaging like MRI or CT scans to pinpoint the compression site, discontinuation of blood-thinning medications, and fasting prior to surgery. While foraminotomy is generally effective, with many patients experiencing significant symptom relief, potential risks include , , , spinal instability, or incomplete resolution of pain. Recovery often involves a short stay of one to two days, use of a soft for procedures, and gradual return to activities, with full benefits appearing over weeks to months through . Outcomes are influenced by factors such as the patient's age, overall health, and the extent of damage, but the procedure's targeted nature makes it a motion-preserving alternative to more extensive spinal surgeries.

Overview

Definition and Purpose

Foraminotomy is a surgical procedure designed to enlarge the , the bony opening through which roots exit the spinal column, thereby relieving pressure on these nerves. This targeted approach addresses foraminal narrowing, allowing the nerve roots to pass more freely without compromising the overall structural integrity of the spine. The primary purpose of foraminotomy is to alleviate symptoms of , including radiating pain, numbness, tingling, and muscle weakness, which arise from due to foraminal or impingement by structures such as spurs or herniated discs. Unlike broader decompressive surgeries that address central , such as , foraminotomy focuses specifically on the lateral foraminal spaces, minimizing disruption to surrounding tissues and preserving spinal stability and motion. Typically performed under general , the procedure lasts about 1 to 2 hours, depending on the complexity and spinal level involved. It can be conducted in the , thoracic, , or sacral regions of the and is often combined with a to remove any disc material contributing to the compression. This combination enhances while maintaining the procedure's minimally invasive potential in select cases.

Historical Development

Foraminotomy emerged in the mid-20th century as a targeted technique to address compression, particularly in the . The procedure was first described in 1944 by neurosurgeons Roy Glen Spurling and William Beecher Scoville, who introduced the posterior laminoforaminotomy approach for treating lateral disc herniations causing . This "keyhole" method involved a midline incision to access and enlarge the , marking a significant advancement over broader laminectomies by minimizing removal while preserving spinal stability. In 1951, Rolf Frykholm further refined the technique, emphasizing the role of degenerative changes and in sleeves, which helped establish foraminotomy as a standard for unilateral . Early open procedures, however, were associated with notable risks due to larger incisions and limited sterile techniques of the era. The adoption of microscopic visualization in the 1970s represented a pivotal , building on the broader introduction of the to by pioneers like M. Gazi Yasargil and Wolfhard Caspar. This allowed for more precise with smaller exposures, reducing tissue trauma and improving outcomes for foraminal stenosis. By the 1980s and 1990s, refinements such as the use of endoscopes expanded minimally invasive options, enabling posterior approaches with incisions under 2 cm to treat disc herniations and osteophytes. A landmark advancement came in 2001 when Tim E. Adamson described the microendoscopic laminoforaminotomy using tubular retractors and endoscopic assistance, which further decreased muscle dissection and blood loss compared to traditional open methods. These developments shifted foraminotomy from inpatient, high-morbidity operations to procedures with success rates for symptom relief exceeding 85-95% in contemporary series. Post-2000 advancements integrated advanced imaging technologies, such as CT- and MRI-guided navigation, enhancing accuracy in complex cases involving multi-level stenosis or anatomical variations. This era also saw the rise of fully endoscopic techniques, with biportal and uniportal systems allowing real-time visualization and reduced radiation exposure. By the 2010s, minimally invasive foraminotomy had evolved to support outpatient settings, with many patients discharged the same day and recovery times shortened to weeks rather than months, reflecting improved perioperative care and instrumentation. In the 2020s, further refinements including robotic-assisted and navigation-guided endoscopic approaches have continued to improve precision and outcomes, with studies as of 2025 reporting sustained radiculopathy relief in over 90% of cases.

Anatomy

Intervertebral Foramen

The , also known as the neural foramen, is an oval-shaped bony tunnel that serves as a passageway for spinal nerves exiting the . It is formed by the pedicles of adjacent vertebrae, the , and the facet joints, creating a conduit between the and the surrounding tissues. The is bounded superiorly and inferiorly by the pedicles of the vertebrae, anteriorly by the vertebral body and , and posteriorly by the facet joints and ligamentum flavum. Within this space, key components include the exiting spinal nerve roots, which carry sensory and motor signals to and from the periphery; in the region, the is also housed here, serving as the site of cell bodies. Additionally, the contains blood vessels such as spinal arteries and veins connecting the internal and external vertebral plexuses, along with and connective elements that provide cushioning. Dimensions of the vary by spinal level, with typical widths ranging from 8 to 12 mm in the region, where the height averages about 19.4 mm (range: 15.5–24.2 mm) and width 8.8 mm (range: 6.4–12.3 mm), peaking at L5–S1. In contrast, the foramina are narrower in the , particularly at –C7, with average widths around 9–12 mm, progressively increasing in size caudally through the thoracic and upper levels. The exiting root typically occupies approximately 20–30% of the foramen's cross-sectional area, leaving space for vascular and elements. Anatomical variations include regional differences in shape and size, with cervical foramina being more triangular and lumbar ones more oval or teardrop-shaped. Age-related changes, such as osteophyte formation from degenerative spondylosis, can progressively reduce foraminal dimensions, potentially leading to narrowing when the minimal diameter falls below 5 mm, at which point space for neural and vascular structures becomes critically limited.

Mechanisms of Nerve Compression

Foraminal stenosis arises primarily from degenerative changes associated with , including degeneration that reduces disc height and allows for formation along the vertebral endplates, thereby encroaching on the space. Additional mechanisms involve hypertrophy, where arthritic enlargement of the superior and inferior articular processes narrows the , and thickening of the ligamentum flavum due to and , which further diminishes the available space for nerve passage. Lateral protrusion or herniation of the can also directly impinge on the exiting within the . The of compression in foraminal involves mechanical pressure from the reduced foraminal dimensions, leading to direct impingement of the against surrounding bony or soft tissue structures. This compression induces ischemia through vascular compromise, resulting in reduced blood flow and oxygenation to the ; concomitant arises from chemical irritation and mechanical stress, promoting , , and potential demyelination of fibers. Irritation often extends to the , amplifying nociceptive signaling and contributing to persistent radicular symptoms. Contributing factors to foraminal narrowing include acute , which may cause immediate structural disruption or accelerate degenerative processes, and repetitive microtrauma from occupational or athletic motions that exacerbate wear on spinal elements. Congenital narrowing of the , though less common, predisposes individuals to earlier onset, while age-related degeneration predominates, with prevalence increasing significantly after age 50 and peaking between 50 and 70 years due to cumulative spondylotic changes. The vast majority of cases—up to 95% in individuals over 50—are linked to and related spondylotic alterations. On (MRI), foraminal compression is typically graded qualitatively: mild (grade 1) involves partial obliteration of perineural fat without morphologic changes to the ; moderate (grade 2) shows fat obliteration in multiple directions with deformation but no collapse; and severe (grade 3) features complete compression and morphologic distortion. This system, based on oblique sagittal views, aids in assessing the extent of narrowing and guides clinical decision-making.

Indications

Common Conditions Treated

Foraminotomy is primarily indicated for conditions involving compression within the , most commonly foraminal , which arises from degenerative changes such as formation or ligamentous that narrow the foraminal space. This condition is prevalent in degenerative spine disease, affecting up to 40% of adults in the region by 60 and becoming increasingly common after 50 due to age-related spinal wear. Lateral disc herniation is another frequent indication, where extruded disc material encroaches on the foraminal opening, compressing exiting nerve roots and often requiring foraminotomy when the herniation is positioned far laterally. In the cervical spine, this typically manifests as with arm pain, weakness, or numbness radiating from the neck, while lumbar cases lead to characterized by leg pain and similar symptoms. Thoracic foraminotomy is rare but may address intercostal nerve involvement causing chest or . Spondylolisthesis with foraminal involvement, where vertebral slippage narrows the , is treated via foraminotomy to decompress affected roots, particularly in degenerative or isthmic types. Post-laminectomy syndrome, involving recurrent foraminal narrowing after prior spinal surgery, also benefits from this procedure to alleviate persistent . These conditions are considered for foraminotomy only after failure of conservative treatments, such as and medications, typically lasting 6-12 weeks without adequate symptom relief. Success rates for foraminotomy in disc-related cases range from 80% to 95%, with high rates of pain relief and functional improvement.

Patient Selection Criteria

Patient selection for foraminotomy begins with comprehensive diagnostic imaging and electrophysiological testing to verify foraminal stenosis and correlate it with clinical symptoms. (MRI) is the primary modality, demonstrating foraminal narrowing, with severe cases often graded as moderate to severe on standardized scales. Computed tomography (CT) serves as an alternative when MRI is contraindicated, providing detailed views of bony and soft tissue compression. Electromyography (EMG) and nerve conduction studies are employed to confirm , identifying patterns and reduced conduction velocities in affected nerve roots. Plain X-rays evaluate spinal alignment and rule out instability that might necessitate alternative interventions. Suitable candidates exhibit persistent, localized unilateral radicular symptoms, such as arm or leg pain, numbness, or weakness, attributable to confirmed foraminal compression, typically following conditions like spinal stenosis. A key prerequisite is failure of non-surgical therapies, including at least 6-8 weeks of physical therapy, nonsteroidal anti-inflammatory drugs (NSAIDs), and transforaminal epidural steroid injections, without adequate relief. Patients should lack signs of widespread myelopathy or multilevel involvement requiring broader decompression. Ideal candidates are adults aged 18 years or older with preserved bone quality to support the procedure's efficacy and minimize risks. Preoperative assessment using the Oswestry Disability Index (ODI), with scores exceeding 40% indicating moderate to severe disability, helps quantify symptom impact and justify surgical intervention. Contraindications include active systemic or local , which could exacerbate postoperative complications, and severe , as it compromises bone integrity and healing. Progressive neurological deficits suggesting instability or the need for also preclude isolated foraminotomy, directing patients toward more comprehensive procedures. A multidisciplinary , involving neurosurgeons, specialists, and radiologists, ensures holistic assessment and optimal decision-making.

Surgical Procedure

Preoperative Preparation

Preoperative preparation for foraminotomy involves a comprehensive evaluation to ensure and optimize surgical outcomes. This begins with a thorough review of the patient's and , including assessment for comorbidities such as , , and . Routine laboratory tests, including (CBC) to evaluate for and coagulation studies (e.g., and ) to assess bleeding s, are typically ordered. For patients over 50 years of age, cardiac clearance is recommended, often involving electrocardiogram (EKG) and consultation with a cardiologist if factors like or prior cardiac events are present, in accordance with perioperative cardiovascular evaluation guidelines. is advised at least 3-4 weeks prior to to reduce the of surgical site infections and improve . Antibiotic prophylaxis is planned, with intravenous administration (e.g., ) typically initiated within 60 minutes before incision to prevent postoperative infections. Patient education is a critical component, where the surgeon discusses the procedure's risks, benefits, and alternatives to ensure informed . Written is obtained after addressing any questions. Patients receive detailed instructions on management, including for 8-12 hours before surgery to minimize risks under , and discontinuing nonsteroidal drugs (NSAIDs) such as ibuprofen at least one week prior to reduce bleeding tendencies; thinners like aspirin or are stopped 7-14 days earlier under guidance. Arrangements for transportation home are emphasized, as impairs driving. Logistical preparations include final review of imaging studies, such as MRI, to confirm the site of and plan the approach, often referencing diagnostic criteria from earlier evaluations. The incision site is marked preoperatively to the surgical team. An consultation is conducted, with particular attention to airway assessment for foraminotomy cases due to potential challenges. For procedures, bowel preparation may be required if an anterior approach is anticipated, involving a clear and laxatives the day before to reduce contamination risks, though evidence suggests limited benefit for posterior decompressions. thrombosis (DVT) prophylaxis is initiated, typically with mechanical methods like devices starting preoperatively, and low-molecular-weight heparin considered for high-risk patients to prevent thromboembolic events. Preparation typically spans 1-2 days, often on an outpatient basis with a confirmation call 1-2 days prior.

Operative Techniques

The operative technique for foraminotomy typically involves a posterior approach under general to decompress the affected by enlarging the . The patient is positioned prone with the head secured in a neutral using a Mayfield clamp or similar device to maintain alignment and facilitate access. General is administered to ensure the patient remains unconscious and pain-free throughout the procedure. A posterior midline or paramedian incision, measuring 2-5 cm in length, is made over the affected vertebral level, confirmed intraoperatively with to ensure accuracy. The paraspinal muscles are dissected and retracted using self-retaining retractors to expose the lamina, , and without excessive stripping to minimize tissue trauma. Bone removal begins with a partial facetectomy, targeting the medial aspect of the superior articular facet and the inferior edge of the superior lamina. A high-speed drill with a diamond burr is used to thin the bone until it becomes translucent, followed by careful resection with Kerrison rongeurs (typically 1-2 mm size) sufficiently to expose the nerve root and relieve compression. Bone removal is limited to no more than 50% of the facet joint to preserve spinal stability and avoid iatrogenic instability. If a herniated disc is present, the nerve root is gently retracted, and disc fragments are removed using a nerve hook and rongeurs. Visualization is enhanced with an operating microscope, though an endoscope may be employed in select cases for magnified views. Hemostasis is achieved with bipolar cautery to control bleeding from bone or soft tissues. The procedure concludes with layered closure: the and muscles are approximated with absorbable sutures, followed by subcutaneous closure and skin approximation using interrupted sutures or staples. A is rarely placed unless significant removal or occurs, and final confirms adequate and hardware placement if applicable. The entire operation typically lasts 60-120 minutes per level treated.

Minimally Invasive Approaches

Minimally invasive approaches to foraminotomy represent an evolution in spinal , emphasizing reduced disruption through and methods to decompress the . These techniques typically involve incisions as small as 1 cm, allowing access via tubular retractors or direct entry, often under with fluoroscopic guidance. Introduced in the with the advent of video-assisted and microendoscopic systems, such as the lumbar microendoscopic discectomy (MED) developed in 1997, these procedures enable precise bone and removal while preserving surrounding structures. Recent advancements as of 2025 include biportal endoscopic techniques and extended transforaminal endoscopic lumbar foraminotomy (FELF) for improved outcomes in complex foraminal . Key techniques include endoscopic foraminotomy, where a working-channel is advanced through the to perform unroofing and using burrs, punches, and . access often employs sequential dilators to create a working portal, followed by full-endoscopic visualization for targeted resection of hypertrophic facets or ligaments. Adjunctive tools such as bipolar radiofrequency for and , or Ho:YAG lasers for , further minimize by enabling controlled removal without extensive mechanical dissection. These methods are particularly suited for single-level (e.g., L4-5, L5-S1) or decompressions, leveraging intraoperative or systems for enhanced precision in navigating neural elements. Advantages of these approaches include significantly reduced blood loss, often negligible or under 50 mL compared to 50-150 mL in open procedures, due to limited muscle retraction and precise targeting. Patients typically experience shorter hospital stays, frequently as outpatients or 1-2 days, facilitating earlier and return to work within 2-4 weeks. Complication rates are approximately 5-10% lower than traditional open , with transient or dural tears being the most common minor issues, attributed to the preservation of paraspinal musculature and reduced risk. Endoscopic systems, particularly those with 30-degree angled , provide near-complete (over 90%) of the surgical field, enhancing and in foraminal .

Postoperative Care

Immediate Recovery

Following foraminotomy, patients typically remain in the hospital for 1 to 2 days to ensure stable recovery. , including , , and , are monitored closely to detect any orthostatic changes or instability. Pain is managed initially with intravenous opioids such as , transitioning to oral analgesics like acetaminophen or as tolerated, with intensity assessed using a visual analog scale (VAS) at rest and during activity. Mobilization is encouraged within 6 to 12 hours post-surgery, starting with assisted ambulation using a to promote circulation and prevent . Wound care involves sterile dressing changes and regular inspection of the incision site for signs of , , or , with any surgical drains removed prior to if placed. Incentive and deep breathing exercises are initiated to maintain expansion and reduce the risk of postoperative . Neurological assessments, including dermatomal and myotomal strength testing, are performed every 4 hours to identify any emerging deficits. Deep vein thrombosis (DVT) prevention includes sequential and early ambulation, with pharmacologic prophylaxis added based on individual risk factors. Nausea from anesthesia is commonly managed with antiemetics such as during the initial recovery phase. Patients are typically discharged directly home, provided they tolerate oral intake, achieve pain control, and demonstrate safe mobility.

Rehabilitation and Long-Term Outcomes

Rehabilitation following foraminotomy typically begins with around 2 to 4 weeks postoperatively, focusing on strengthening, correction, and gentle range-of-motion exercises to support spinal stability and prevent compensatory habits. Patients are advised to avoid heavy lifting or strenuous activities for 6 to 8 weeks to allow healing, with sessions often occurring 2 to 3 times per week for 6 to 8 weeks. Follow-up imaging, such as X-rays or MRI, is commonly performed at 6 weeks to assess and . Long-term outcomes demonstrate high efficacy, with 84% to 94% of patients achieving significant relief at 2 years and approximately 85% showing sustained in symptoms at 4 years. Functional improvements, measured by tools like the Visual Analog Scale (VAS) for and Oswestry Disability Index () for daily activities, indicate enhanced mobility and reduced disability in the majority of cases. Recurrence risk stands at 10% to 15% over 5 years, often necessitating reoperation in about 9.9% of patients within 2.4 years on average. Patient satisfaction exceeds 80%, with over 90% reporting better , weakness, or function long-term. Full recovery generally occurs within 3 to 6 months, though complete healing may take up to 1 year, during which patients for desk-based jobs can return to work in 4 to 6 weeks. Lifestyle modifications, including weight management and ergonomic adjustments to reduce spinal load, are recommended to optimize outcomes and minimize re-compression risks. In cases of developing instability (occurring in about 5% of patients), spinal fusion may be required as a subsequent intervention.

Risks and Complications

Intraoperative Risks

Intraoperative risks during foraminotomy primarily involve vascular, neural, and dural structures due to the proximity of the neural foramen to critical in the or . Excessive from the epidural venous is a common challenge, particularly in posterior approaches, where disruption can lead to significant intraoperative blood loss averaging 100-300 , though minimally invasive techniques reduce this to 40-140 . This is typically managed through , , or hemostatic agents to maintain visibility and prevent hemodynamic instability. Dural tears occur in approximately 1-4% of cases, with higher rates up to 9% reported in some decompressions, often repaired intraoperatively using sutures, dural sealants, or to avoid leakage. Nerve root injury, manifesting as immediate motor or sensory deficits, has an incidence of 1-2.3%, resulting from direct trauma during drilling or retraction, and can be mitigated by intraoperative neuromonitoring such as somatosensory evoked potentials (SSEP) and motor evoked potentials (), which provide real-time feedback to reduce neurological risks. Anesthesia-related complications include from fluid shifts or blood loss, occurring in up to 20% of prone surgeries, and rare allergic reactions to agents like anesthetics or antibiotics. Positioning in the prone setup for posterior foraminotomy carries risks of ocular injury, such as perioperative visual loss from ischemic , linked to prolonged pressure, , or , with an incidence below 0.2% but potentially devastating. Technical risks, such as incomplete due to inadequate removal, may lead to persistent symptoms if not addressed, while instrument breakage remains rare at less than 1%.

Postoperative Complications

Postoperative complications following foraminotomy can occur in 5-15% of cases overall, though rates vary by approach and patient factors. Common immediate issues include , with superficial and deep surgical site infections reported at 2-5%, particularly elevated in posterior approaches due to proximity to . These infections are managed promptly with intravenous antibiotics, often resolving without long-term sequelae, though severe cases may necessitate . Cerebrospinal fluid (CSF) leak, typically arising from an intraoperative dural tear, affects approximately 2-5% of patients and presents as persistent positional or clear drainage from the wound. with bed rest, hydration, and lumbar drainage suffices in most instances, but persistent leaks may require surgical repair to prevent . Spinal is a concern when more than 50% of the is removed during , occurring in up to 3-5% of cases and potentially necessitating subsequent . Bracing and activity restriction are initial interventions, with reserved for symptomatic confirmed by imaging. Delayed complications include epidural or formation around the , contributing to reoperation in about 10% of revision cases due to recurrent symptoms. Adjacent develops at a rate of approximately 0.7% annually, reaching 6-7% over 10 years, often managed conservatively before considering further intervention. syndrome, akin to failed back surgery syndrome, persists in 10-15% of patients, linked to incomplete or , and treated with multidisciplinary approaches including medications and injections. Risk factors such as double the infection risk through impaired and . Mortality remains rare at less than 0.1%, primarily from unrelated comorbidities rather than procedure-specific issues. Revision addresses recurrence or unresolved compression in 4-7% of patients overall.

Foraminectomy

Foraminectomy refers to the complete or near-complete excision of the roof, primarily involving the superior articular facet of the , to achieve extensive neural in the spinal . This is employed when foraminotomy provides insufficient relief, targeting severe compression of the . Unlike partial techniques, foraminectomy removes the entire superior along with associated ligamentum flavum, often necessitating concomitant to maintain . Indications for foraminectomy are limited to cases of severe multilevel foraminal unresponsive to or less invasive surgeries, as well as intraspinal tumors such as lumbar tumors ( type 2 or 3) that cause symptomatic neural and progression. It is rarely performed due to the substantial risk of postoperative spinal instability, which can exceed 18% in decompressive procedures involving extensive facet removal. In tumor cases, foraminectomy facilitates gross total resection, achieving 100% complete removal in select minimally invasive approaches without requiring secondary operations. Compared to standard foraminotomy, which typically resects 30-50% of the to enlarge the while preserving motion, foraminectomy involves 70-100% facet removal, significantly increasing the likelihood of segmental and often mandating instrumented . Success rates for pain relief from 58% to 80% in open microforaminotomy variants incorporating total facetectomy. Its use has declined since the early with the advent of minimally invasive endoscopic and biportal techniques that achieve comparable with lower risks and better preservation of spinal .

Laminectomy and Laminotomy

involves the complete removal of the lamina, the bony arch at the back of one or more vertebrae, to widen the and alleviate compression on the or nerve roots, primarily indicated for central where bony overgrowth narrows the canal. This procedure addresses symptoms such as leg pain, numbness, and weakness by creating substantial space in the central canal, often requiring across multiple levels due to the diffuse nature of central . However, the extensive removal can lead to , with secondary rates reported at approximately 10-13% in patients undergoing open without initial stabilization. In contrast, laminotomy entails partial removal of the lamina, typically creating a small window to access and decompress the while preserving much of the surrounding bone structure for stability. This approach is less invasive than full , reducing disruption to paraspinal muscles and ligaments, and is frequently employed for targeted in cases involving herniated discs or synovial cysts alongside central . is often combined with foraminotomy in multilevel to address both narrowing and lateral foraminal compression, as seen in studies of posterior lumbar procedures where such hybrid techniques provide comprehensive relief for combined pathologies. Unlike foraminotomy, which focuses on enlarging the lateral to relieve entrapment at a single level, and target the central to manage broader from ligamentous or , typically spanning 2-3 vertebral levels in degenerative cases. Foraminotomy remains more focal and preserves posterior elements to a greater degree, avoiding the need for extensive canal widening. Combined laminoforaminotomy procedures, integrating central and lateral , are commonly utilized in up to 80% of foraminal surgeries requiring additional canal access. Recovery from laminectomy generally spans 6-12 weeks for full functional return, influenced by the procedure's scope and any concurrent fusion, with patients often hospitalized for 1-2 days and restricted from heavy lifting for several weeks. Foraminotomy, being less disruptive, allows for a shorter of 4-6 weeks, enabling earlier resumption of light activities and minimizing postoperative . Laminotomy falls between these, offering faster healing than due to preserved stability but similar to foraminotomy in outpatient potential for select cases.

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