Fact-checked by Grok 2 weeks ago

Frequency-dependent selection

Frequency-dependent selection is a mode of natural selection in evolutionary biology in which the fitness of a genotype, phenotype, or allele varies as a function of its relative frequency in the population, rather than being constant across all conditions. This dependence arises because interactions among individuals, such as competition, predation, or mating, create selective pressures that change with the composition of the population.^[1] The concept gained prominence in the 1970s through reviews in population genetics and behavioral ecology.^[2] There are two primary forms of frequency-dependent selection: negative and positive. In negative frequency-dependent selection, the fitness of a type increases when it is rare and decreases when it is common, often stabilizing polymorphisms by favoring rarity and preventing any single variant from dominating the population. Conversely, positive frequency-dependent selection occurs when the fitness of a type increases with its frequency, reinforcing the spread of common variants and potentially leading to fixation or loss of diversity, as seen in processes like positive assortative mating.^[1] These dynamics are frequently modeled using evolutionary game theory, where strategies' payoffs depend on their prevalence, as pioneered by John Maynard Smith. Frequency-dependent selection plays a crucial role in maintaining genetic variation, influencing speciation, and mediating adaptation to changing environments, including scenarios of evolutionary rescue from extinction.^[3] Recent studies, including meta-analyses as of 2024 and experiments in 2025, underscore its ubiquity in maintaining variation across taxa.^[4]^[5] Notable examples include color polymorphisms in damselflies, where male mate preferences drive negative frequency-dependent selection on female morphs,^[6] and predator-prey systems like the scale-eating fish Perissodus microlepis, where left- and right-mouthed individuals balance via negative frequency dependence.^[7] In human-related contexts, it has been invoked in models of infectious disease dynamics, where pathogen virulence evolves based on host susceptibility frequencies.^[8] Overall, this selective mode underscores how population-level interactions shape evolutionary trajectories beyond simple directional pressures.^[9]

Fundamentals

Definition

Frequency-dependent selection is a mechanism of natural selection in evolutionary biology wherein the fitness of a genotype or phenotype is not fixed but varies as a function of its relative frequency within the population.^[10] This contrasts with frequency-independent selection, in which the fitness of a genotype or phenotype remains constant irrespective of its prevalence in the population. In frequency-dependent selection, interactions such as competition, predation, or mating success among individuals cause the adaptive value of a trait to change depending on how common or rare it is relative to alternatives.^[10] This form of selection differs from other types, such as directional or stabilizing selection, which generally operate under the assumption of constant fitness values across varying trait distributions; frequency-dependent selection uniquely incorporates the population's composition as a dynamic variable that directly influences relative fitness. To understand this process, key concepts from population genetics are essential: the allele frequency p represents the proportion of a specific allele in the gene pool; genotype fitness w denotes the relative reproductive success or survival rate of individuals carrying that genotype; and mean fitness \bar{w} is the average fitness across all genotypes in the population, serving as a normalizing factor.^[10] These terms build on the foundational principles of natural selection, where heritable variation in fitness leads to changes in allele frequencies over generations. In mathematical terms, the change in allele frequency \Delta p under selection can be expressed in a general form for a two-allele system as

\Delta p = \frac{p(1-p)(w_1 - w_2)}{\bar{w}},

where w_1 and w_2 are the marginal fitnesses of the two alleles, and \bar{w} is the mean population fitness.^[10] Under frequency dependence, w_1 and w_2 are themselves functions of p, reflecting how allele interactions alter fitness based on abundance. This formulation highlights how frequency-dependent selection can stabilize polymorphisms by adjusting fitness dynamically.

Historical Context

The concept of frequency-dependent selection has roots in the early experimental observations of the modern synthesis era, where Sewall Wright and Theodosius Dobzhansky noted that genotypic fitness in populations of Drosophila pseudoobscura varied with allele frequencies during laboratory studies of chromosomal inversions. This work, published in 1946, provided initial empirical evidence that selection pressures could shift based on relative abundances, building on Wright's earlier shifting balance theory from the 1930s, which emphasized how drift and selection in subdivided populations could lead to dynamic frequency changes across adaptive peaks.^[11] Ronald Fisher and J.B.S. Haldane, key architects of the modern synthesis, had primarily modeled selection with constant fitness coefficients, but these early findings highlighted gaps in explaining persistent genetic polymorphisms beyond simple heterozygote advantage.^[2] The concept was first formalized in the 1960s through theoretical and experimental advances in population genetics, particularly by Francisco J. Ayala, who demonstrated frequency-dependent effects in interspecific competition and mating success in Drosophila species.^[12] Ayala's 1971 paper explicitly described how competitive fitness between species declines as their relative frequencies increase, providing a mechanistic basis for coexistence.^[12] This was followed by the seminal 1974 review by Ayala and Cathryn A. Campbell, which synthesized experimental evidence and theoretical models, establishing frequency-dependent selection as a key form of balancing selection that addresses limitations in the modern synthesis by maintaining polymorphisms through dynamic fitness interactions rather than solely overdominance.^[2] A major milestone came in 1969 with Bryan Clarke's analysis of negative frequency dependence in Batesian mimicry systems, where rare morphs gain protection from predators, promoting balanced polymorphisms in sympatric species.^[13] Clarke's subsequent 1979 review further solidified the empirical support for apostatic selection in mimicry and molecular polymorphisms, emphasizing its role in diversity maintenance.^[14] In the 1980s, John Maynard Smith integrated the concept into evolutionary game theory, using evolutionarily stable strategies to model frequency-dependent outcomes in behavioral interactions, as detailed in his 1982 book. Later evolutionary ecologists, such as Joan Roughgarden, expanded the idea beyond genetics to ecological contexts, incorporating frequency and density dependence in models of resource competition and social systems during the late 1970s and 1980s. This progression highlighted how frequency-dependent selection complemented the modern synthesis by providing a versatile framework for understanding evolutionary stability in complex, interactive populations.

Types

Positive Frequency-Dependent Selection

Positive frequency-dependent selection is a form of natural selection in which the fitness of a particular phenotype or genotype increases as its frequency rises within a population, thereby conferring a relative advantage to more common variants.^[1] This dynamic arises because rare phenotypes often experience reduced fitness due to mismatches with prevailing ecological or social conditions, while common ones benefit from alignment with those conditions.^[15] Key mechanisms driving this process include social conformity, where individuals gain advantages by matching dominant behaviors in group interactions, such as in the evolution of cooperative traits among group-living animals; predator avoidance through majority signaling, as predators more readily learn to avoid widespread warning patterns; and resource specialization, where frequent phenotypes optimize exploitation of specific niches, enhancing efficiency as they become prevalent.^[16] The fitness landscape under positive frequency-dependent selection can be modeled with functions where relative fitness rises linearly with frequency, such as w(p) = 1 + s p, with s > 0 representing the positive selection coefficient and p the frequency of the phenotype.^[1] Here, the fitness of the common type exceeds that of rarer alternatives, creating a snowball effect that accelerates the spread of the dominant variant. Equilibria where frequencies are low for the advantageous type are unstable, as any slight increase in frequency tips the balance toward further proliferation, while deviations decrease it toward elimination.^[15] Evolutionarily, this form of selection typically results in the loss of genetic variation, as it drives the fixation of a single allele or phenotype, reducing polymorphism within the population.^[1] Unlike negative frequency-dependent selection, which favors rarity and sustains diversity, positive frequency-dependent selection promotes uniformity by rewarding commonality. A conceptual diagram of this process illustrates a payoff matrix where the common strategy yields higher reproductive success against itself and especially against rare alternatives, depicted as an upward-sloping fitness curve with frequency on the x-axis and relative fitness on the y-axis, showing divergence from the unstable low-frequency equilibrium toward fixation at p = 1.^[15]

Negative Frequency-Dependent Selection

Negative frequency-dependent selection is a form of balancing selection in which the fitness of a phenotype or genotype declines as its frequency within the population increases, thereby providing a relative fitness advantage to rarer variants and promoting genetic diversity.^[17] This process favors the persistence of multiple alleles or morphs by ensuring that uncommon types experience higher per capita reproductive success compared to abundant ones.^[18] The mechanism underlying this selection often involves negative biotic interactions that disproportionately affect common types while allowing rare types to evade disadvantages. In predation scenarios, rare prey phenotypes are less likely to be detected or preferentially targeted by predators, which develop search images or foraging biases toward prevalent morphs, leading to elevated survival for the uncommon variants.^[17] Similarly, in host-parasite systems, rare host genotypes incur lower infection rates because parasites or pathogens are adapted to exploit the most frequent host types, resulting in reduced parasite load for rarer hosts.^[17] For intraspecific competition, common phenotypes face intensified rivalry for limited resources, such as niche overlap in foraging or habitat use, which saturates their fitness gains and diminishes their competitive edge relative to rarer competitors with access to underutilized opportunities.^[18] These interactions create a feedback loop where the rarity itself confers protection, amplifying the selective pressure against dominance by any single type.^[17] Mathematically, the fitness of a phenotype under negative frequency-dependent selection decreases as a function of its frequency p; a simple linear example is given by

w(p) = 1 - s p,

where s > 0 is the selection coefficient, ensuring that relative fitness is highest when p is low and declines as p approaches 1, thus benefiting rare phenotypes.^[17] More generally, fitness curves exhibit a negative slope with respect to frequency, often crossing to allow mutual invasibility between types.^[18] The evolutionary outcomes of this selection include stable polymorphism, where multiple phenotypes or alleles coexist at equilibrium frequencies determined by the balance of their frequency-dependent fitnesses, preventing fixation or loss of variants.^[17] It can also generate cycles in allele frequencies, with rare types rising in abundance until they become common and subsequently decline, or establish protected polymorphisms that safeguard rare alleles from elimination even under genetic drift.^[18] Equilibria arise when the average fitnesses equalize, typically around intermediate frequencies where no single type holds a net advantage.^[17] A conceptual diagram illustrating this process typically shows a balancing selection curve plotting relative fitness against frequency: the line for a given allele starts high at low frequencies (enabling invasion by rares), slopes downward as frequency rises (reflecting declining fitness for commons), and intersects the equilibrium line (often at y = 1 for relative reproductive success), demonstrating how rare alleles spread while common ones recede until coexistence is achieved.^[17]

Mathematical Models

Population Genetic Frameworks

In population genetics, the foundational framework for modeling frequency-dependent selection begins with the discrete-generation model for a diallelic locus in an infinite, randomly mating population. The change in allele frequency from one generation to the next is given by

\Delta p = \frac{p q (w_A(p) - w_a(p))}{\bar{w}(p)},

where p is the frequency of allele A, q = 1 - p is the frequency of allele a, w_A(p) and w_a(p) are the frequency-dependent marginal fitnesses of the alleles, and \bar{w}(p) = p w_A(p) + q w_a(p) is the mean population fitness.^[19]^[10] This equation generalizes the standard selection model by allowing fitnesses to vary as functions of p, capturing how interactions among genotypes influence evolutionary change. A continuous-time approximation facilitates analytical tractability for gradual changes, particularly when generations overlap or selection is weak. The dynamics are approximated as

\frac{dp}{dt} = p(1-p) s(p),

where s(p) represents the frequency-dependent selection gradient, often defined as s(p) = (w_A(p) - w_a(p)) / \bar{w}(p) or a similar normalized difference in relative fitnesses.^[19]^[20] This differential equation describes the rate of allele frequency evolution as a product of genetic variance p(1-p) and the selective advantage, enabling predictions of trajectories toward fixation or polymorphism under varying fitness dependencies.^[20] Equilibria occur where \Delta p = 0 or dp/dt = 0, which holds when w_A(\hat{p}) = w_a(\hat{p}) = \bar{w}(\hat{p}) at some interior frequency \hat{p}. For stable polymorphism, local stability requires that the selection gradient diminishes as the allele becomes more common, specifically when \partial (w_A - \bar{w}) / \partial p < 0 evaluated at \hat{p}.^[19]^[20] This condition ensures that deviations from \hat{p} induce restorative selection, maintaining genetic variation; conversely, the opposite inequality leads to unstable equilibria and potential loss of polymorphism.^[19] These models assume an infinite population size to neglect stochastic drift, random mating with no linkage disequilibrium beyond the locus of interest, discrete non-overlapping generations (or continuous approximation thereof), and absence of mutation, migration, or other evolutionary forces.^[19]^[10] Extensions to finite populations incorporate drift via diffusion approximations but retain the core deterministic dynamics for large N.^[19] Such frameworks apply to both positive and negative frequency-dependent selection by specifying appropriate forms of w_A(p) and w_a(p).

Game Theory Applications

Evolutionary game theory provides a framework for modeling frequency-dependent selection by incorporating strategic interactions among individuals, where the fitness of a strategy depends on its frequency in the population. In the 1970s, John Maynard Smith integrated classical game theory into evolutionary biology, adapting concepts from economics to analyze animal behavior and selection pressures that vary with strategy prevalence. This approach emphasizes payoffs from interactions rather than fixed traits, allowing for the prediction of stable outcomes under frequency dependence. A central concept is the evolutionarily stable strategy (ESS), which is a strategy that, if adopted by most individuals in a population, resists invasion by alternative strategies. Formally, a strategy I is an ESS if, for any mutant strategy J \neq I, either the expected fitness of I against a population of I exceeds that of J against I, denoted w(I, I) > w(J, I), or if w(I, I) = w(J, I), then w(I, J) > w(J, J). Here, fitnesses w are frequency-dependent, calculated as weighted averages of payoffs based on the proportions of strategies encountered. This criterion captures how selection favors strategies that perform well against themselves while exploiting or resisting rarer alternatives.^[21] The Hawk-Dove game illustrates these principles in conflicts over resources, such as territory or mates, with two pure strategies: Hawk (escalate to fight) and Dove (display and retreat). The payoff matrix assigns values based on outcomes: Hawk versus Hawk yields (V - C)/2 for each (where V is resource value and C > V is fight cost), Hawk versus Dove yields V for Hawk and 0 for Dove, and Dove versus Dove yields V/2 each. Let p be the frequency of Hawk; the fitness of Hawk is then w_H(p) = p \cdot \frac{V - C}{2} + (1 - p) \cdot V, and for Dove, w_D(p) = p \cdot 0 + (1 - p) \cdot \frac{V}{2}. When C > V, no pure strategy is an ESS; instead, a mixed ESS emerges at p^* = V/C, where rare strategies have higher fitness, exemplifying negative frequency-dependent selection that maintains polymorphism. Invasion analysis shows that deviations from p^* favor the underrepresented strategy, stabilizing the equilibrium. These models link directly to types of frequency-dependent selection: negative dependence often produces cycles or stable mixtures, as in Hawk-Dove where increasing frequency reduces a strategy's relative payoff, promoting diversity; positive dependence can yield bistability, with two pure ESSs where the invading strategy fails if the resident is common, leading to alternative stable states based on initial conditions. Such dynamics highlight how strategic interactions drive evolutionary outcomes beyond simple allele frequencies.^[21]^[22]

Examples

Predation and Mimicry

In Müllerian mimicry, multiple species of unpalatable or toxic organisms evolve similar warning signals, such as bright coloration patterns, to deter predators collectively. This system exemplifies positive frequency-dependent selection (FDS), where the fitness of a mimetic morph increases as its frequency rises in the population. Rare morphs experience higher predation rates because predators are less likely to have learned to avoid them, whereas common morphs benefit from shared defensive education of predators across the mimicry ring. For instance, field experiments using artificial butterfly models matching local Heliconius wing patterns demonstrated that predation by birds was significantly higher on rare morphs compared to common ones, supporting positive FDS in maintaining mimicry convergence.^[16] Apostatic selection represents a form of negative FDS in predator-prey interactions, where predators develop search images for abundant prey morphs, resulting in disproportionately higher predation on common phenotypes and relative safety for rare ones. This mechanism helps maintain color polymorphisms in prey populations by favoring rarity. In guppies (Poecilia reticulata), natural populations exhibit extreme male color pattern diversity, which is sustained by such predation-driven selection. Mark-recapture studies in wild Trinidadian streams showed that male guppies with rare color patterns had higher survival rates than those with common patterns, providing direct evidence of negative FDS acting on visual polymorphisms.^[23] Host-parasite coevolution often involves negative FDS, where rare host genotypes confer resistance to prevalent parasite strains, thereby preserving genetic diversity at loci like the major histocompatibility complex (MHC). MHC molecules present parasite antigens to the immune system, and heterozygosity or rare alleles enhance resistance to common pathogens, preventing any single genotype from dominating. In Soay sheep (Ovis aries), MHC class II variation correlates with juvenile survival and resistance to intestinal nematodes (strongyles), with rare alleles showing superior protection against circulating strains. This dynamic maintains high MHC polymorphism through antagonistic coevolution.^[24] Laboratory experiments with Daphnia magna and its bacterial parasite Pasteuria ramosa illustrate negative FDS in host-parasite systems, where infection success depends on matching host and parasite genotypes, akin to predation rates varying with genotypic frequency. In coevolution assays, rare host clones resisted common parasite isolates more effectively, leading to fluctuating selection that sustains clonal diversity. These controlled infections revealed that parasite transmission rates declined for common host-parasite combinations, mirroring frequency-dependent predation dynamics and supporting the role of such interactions in polymorphism maintenance.^[25]^[26] In mate choice systems, positive frequency-dependent selection can arise when females preferentially select males exhibiting the most common traits, thereby accelerating the fixation of those traits within the population. This dynamic is exemplified in models of sexual selection in Drosophila, where preferences for prevalent male phenotypes create a mating advantage that reinforces the dominance of common types. For instance, O'Donald's encounter models demonstrate that partial choosiness by females leads to frequency-dependent mating success, favoring common male traits and hastening their spread under positive selection pressures.^[27] Such mechanisms contrast with rare-male advantages but highlight how conformity in mate preferences can drive rapid evolutionary fixation in insect populations.^[28] Social foraging behaviors in birds often exhibit positive frequency-dependent selection through conformity, where individuals adopting the majority strategy gain advantages in group dynamics. In experimental studies with house sparrows, rare joining strategies are exploited by conformist groups, reducing the fitness of nonconformists and favoring the spread of common foraging tactics. This conformity promotes efficient resource exploitation in flocks, as individuals copying the prevalent behavior experience higher success rates when personal information conflicts with social cues.^[29] Similar patterns occur in wild bird populations, where positive frequency dependence stabilizes group-level foraging norms, enhancing overall survival in variable environments.^[30] Negative frequency-dependent selection plays a key role in maintaining cooperation in microbial biofilms via kin recognition mechanisms that punish rare cheaters. In bacterial communities, such as those formed by Pseudomonas species, rare cheater mutants exploiting public goods like extracellular polymers face targeted suppression through mechanisms like quorum-sensing-mediated policing, which reduces their relative fitness when infrequent. This dynamic ensures that cooperation persists, as the advantage to cheaters diminishes with their commonality, stabilizing polymorphic populations. Empirical tests with Myxococcus xanthus confirm that cheaters undergo negative frequency-dependent selection, with their invasion success limited by group-level sanctions that favor cooperators in biofilms.^[31] Such processes underscore how social recognition enforces altruism in microbial social systems.^[32] Field studies on pollination in the elderflower orchid (Dactylorhiza sambucina) reveal negative frequency-dependent selection favoring rare flower morphs through enhanced reproductive success. In this rewardless species, purple and yellow morphs exhibit a polymorphism maintained by pollinator preferences, where rarer colors receive disproportionately higher visitation and pollination rates due to pollinator generalization and search image formation. Manipulative experiments altering morph frequencies demonstrated that rare morphs achieve up to twofold greater male and female reproductive success, directly attributing this to negative selection dynamics.^[33] This mechanism parallels ecological processes like predation but operates via pollinator behavior in plant reproductive systems, sustaining floral diversity without rewards.^[34]

Implications

Polymorphism Maintenance

Negative frequency-dependent selection serves as a primary mechanism of balancing selection, counteracting the tendency for directional selection to drive alleles toward fixation by favoring rarer variants within a population. This dynamic process ensures that no single genotype dominates, thereby preserving genetic and phenotypic diversity over time. A classic example involves the human leukocyte antigen (HLA) system, where extensive allelic diversity is sustained by pathogen-driven negative frequency-dependent selection. Pathogens adapt to exploit common HLA alleles for immune evasion, conferring a selective advantage to rarer alleles that better resist infection and thereby perpetuate high polymorphism levels across human populations.^[35]^[36] Different ABO blood types confer varying resistance to infectious diseases, including malaria caused by Plasmodium falciparum, contributing to balancing selection that maintains polymorphism.^[37]^[38] The genetic outcome of this selection regime is the establishment of protected polymorphisms, in which multiple alleles coexist at stable equilibrium frequencies greater than zero. Under negative frequency-dependent selection, the relative fitness of an allele rises as its frequency falls, creating a feedback loop that stabilizes diversity and resists erosion by other evolutionary forces. This results in populations harboring a broader array of genotypes than would occur under constant or positive frequency-dependent selection.^[10]^[39] Strong empirical support for polymorphism maintenance comes from the human leukocyte antigen (HLA) system, where extensive allelic diversity is sustained by pathogen-driven negative frequency-dependent selection. Pathogens adapt to exploit common HLA alleles for immune evasion, conferring a selective advantage to rarer alleles that better resist infection and thereby perpetuate high polymorphism levels across human populations.^[35]^[36] Despite its efficacy, negative frequency-dependent selection's ability to maintain polymorphisms is conditional and can fail under certain demographic and ecological pressures. In small populations, genetic drift dominates, randomly fixing or eliminating alleles and overriding the stabilizing effects of selection. High migration rates similarly undermine persistence by homogenizing allele frequencies across subpopulations, disrupting the local rarity advantages essential for balance; effective maintenance requires selection strengths that surpass both drift (inversely proportional to population size) and migration intensities.^[40]^[41]^[8]

Evolutionary Dynamics

Frequency-dependent selection (FDS) profoundly influences long-term evolutionary processes by shaping adaptation rates, promoting speciation, and driving coevolutionary dynamics. In particular, positive FDS accelerates the fixation of beneficial traits in fluctuating environments, as the increasing prevalence of an advantageous variant enhances its relative fitness, creating a positive feedback loop that hastens its spread to fixation once it surpasses an initial threshold.^[42] This mechanism contrasts with constant selection, where fixation proceeds at a more linear pace, and is especially relevant when environmental shifts favor initially rare innovations, allowing populations to track changes more rapidly. Mathematical models of FDS have demonstrated that such dynamics can enhance overall adaptive potential under variable conditions.^[20] FDS also contributes to speciation by fostering reproductive isolation through frequency-dependent mate preferences. In cichlid fishes of African lakes, such as species in the genus Pundamilia, females exhibit preferences for conspecific male coloration that intensify when rare phenotypes are involved, selecting against hybrids and promoting genetic divergence.^[43] This negative FDS in mating systems generates disruptive selection, accelerating the evolution of prezygotic barriers and explaining rapid radiations, as seen in Lake Victoria where declining speciation rates align with predictions from frequency-dependent models of mate choice.^[44] Such processes highlight FDS's role in macroevolutionary diversification without requiring ecological niche partitioning. In coevolutionary contexts, negative FDS sustains oscillatory dynamics in host-parasite interactions, embodying the Red Queen hypothesis where hosts must continually evolve to counter evolving parasites. Experimental coevolution between the freshwater snail Potamopyrgus antipodarum and the trematode Microphallus sp. revealed that common host genotypes decline in frequency under parasite pressure, while rare genotypes increase, leading to cyclic shifts in genotypic dominance over generations.^[45] This rare-type advantage drives perpetual arms races, maintaining diversity and preventing fixation of any single resistance strategy, as parasites adapt to prevalent hosts, thereby fueling ongoing evolution.^[39] Contemporary applications of FDS underscore its relevance to human-induced evolutionary challenges, notably in the spread of antibiotic resistance. In clinical populations of Escherichia coli carrying extended-spectrum β-lactamase plasmids, rare resistant strains exhibit higher relative fitness at low frequencies due to negative FDS, facilitating their rapid proliferation even without antibiotics and stabilizing resistance at intermediate levels post-exposure.^[46] This dynamic explains the persistence of resistance genes in bacterial communities, complicating control efforts and illustrating how FDS can amplify adaptive responses to selective pressures like antimicrobial use.^[47]

References

[1]
How frequency‐dependent selection affects population fitness ...
Frequency‐dependent (FD) selection is a central process maintaining genetic variation and mediating evolution of population fitness.
[2]
https://www.annualreviews.org/doi/abs/10.1146/annurev.es.05.110174.000555
[3]
Frequency dependence and the predictability of evolution in a ...
Frequency-dependent (FD) selection, whereby fitness and selection depend on the genetic or phenotypic composition of the population, arises in numerous ...
[4]
Negative Frequency-Dependent Selection Is Frequently Confounding
Prominent population geneticists including Williams and Maynard Smith, among many others, have demonstrated that the efficacy of natural selection decreases at ...
[5]
The enigma of frequency-dependent selection - ScienceDirect.com
The original concept of frequency-dependent selection arose from two lines of thinking. First, it was recognized that fitness values are not usually constant.Abstract · Frequency Dependence And... · Concluding Remarks
[6]
Frequency-Dependent Selection and the Maintenance of Genetic ...
When individuals' fitnesses depend on the genetic composition of the population in which they are found, selection is then frequency dependent.
[7]
S SHIFTING BALANCE THEORY OF EVOLUTION - Oxford Academic
Feb 2, 2025 · Such frequency-dependent selection maintains ho- mogeneous warning patterns both within species and between species that are part of the ...
[8]
Competition between Species: Frequency Dependence - Science
This frequency-dependent fitness leads to a stable coexistence of the two species in spite of their competition for limited resources.
[9]
The Evolution of Genetic Diversity - jstor
Even in the absence of mimicry, predators select in a frequency-dependent manner (Clarke I962, I969). They concentrate disproportionately on common.
[10]
Chapter 5 Evolutionary Mechanisms I: Modeling Selection
We distinguish two types of frequency-dependency: positive and negative. In positive frequency-dependent selection, the fitness of a genotype increases as it ...
[11]
Warning signals are under positive frequency-dependent selection ...
Feb 8, 2016 · Positive frequency-dependent selection (FDS) is a selection regime where the fitness of a phenotype increases with its frequency, and it is ...<|control11|><|separator|>
[12]
https://www.science.org/doi/10.1126/science.171.3973.820
[13]
https://www.nature.com/articles/hdy196952
[14]
[PDF] THEORETICAL EVOLUTIONARY GENETICS JOSEPH FELSENSTEIN
... dp/dt, getting dp dt. = s p2(1 − p). 1 + s p2 . (II-96). This differential ... frequency-dependent selection in which the rare allele is at an advantage ...
[15]
How frequency‐dependent selection affects population fitness ...
Sep 19, 2018 · Classical theory, dating back to the 1940s, demonstrated that frequency dependence can either increase or decrease population fitness. These ...
[16]
Evolutionary Game Theory - Stanford Encyclopedia of Philosophy
Jan 14, 2002 · In 1982, Maynard Smith's seminal text Evolution and the Theory of Games appeared, followed shortly thereafter by Robert Axelrod's famous work ...
[17]
Half a century of evolutionary games: a synthesis of theory ...
Mar 20, 2023 · Evolutionary game theory, with its explicit incorporation of frequency-dependent selection into evolutionary thinking, was one of the great leaps forward since ...
[18]
Major histocompatibility complex variation associated with juvenile ...
Antagonistic coevolution between hosts and parasites has been proposed as a mechanism maintaining genetic diversity in both host and parasite populations.
[19]
MHC allele frequency distributions under parasite-driven selection
Oct 27, 2010 · The aim of our study was to compare frequency distributions of MHC alleles in simulations that mimicked host-parasite coevolution under three ...
[20]
The Daphnia magna-Pasteuria ramosa model | PLOS Genetics
Matching-allele interactions of hosts and parasites that prevent the emergence of host and parasite genotypes that are universally resistant and infective are a ...
[21]
No evidence for frequency-dependent selection acting between ...
Dec 1, 1981 · Ayala, F J, and Campbell, C A. 1974. Frequency dependent selection. Ann Rev Ecol Syst, 5, 115–138. Article Google Scholar. Banta, A M, Wood ...
[22]
Frequency-dependent sexual selection as a result of variations in ...
Jun 1, 1973 · Darwin's model of sexual selection by variations in fitness at breeding time is generalised to allow for the sexual advantage of the ...
[23]
Frequency-dependent sexual selection - Journals
The O'Donald and Charlesworth encounter models are shown to produce a very similar frequency-dependent relation. Generally, as females become less choosy, they ...
[24]
role of conformity in foraging when personal and social information ...
In conclusion, the findings of this study show that positive frequency-dependent social learning, or conformity, can promote social learning in naïve ...
[25]
Effects of positive frequency-dependent learning, learning mistakes ...
Jun 8, 2023 · Potent social learning and conformity shape a wild primate's foraging decisions. Science 340, 483–485. doi: 10.1126/science.1232769. PubMed ...
[26]
Frequency Dependence and Cooperation: Theory and a Test with ...
The developmental, physiological, neural and genetic causes and consequences of frequency‐dependent selection in the wild. Annual Review of Ecology ...<|control11|><|separator|>
[27]
Facultative cheating supports the coexistence of diverse quorum ...
Next, we find that cocultured pherotypes undergo negative frequency-dependent selection by mutual facultative cheating during swarming. Finally, we show that ...
[28]
Negative frequency-dependent selection maintains a dramatic ...
The Elderflower orchid Dactylorhiza sambucina is a rewardless species that has a striking purple-yellow flower-color polymorphism (Fig. 1). This ...
[29]
Negative frequency-dependent selection maintains a ... - PubMed
May 22, 2001 · We show here clear evidence from this manipulative experiment that rare-color morphs have reproductive advantage through male and female components.
[30]
The relationship between blood groups and disease
Available evidence suggests surviving malaria is the most significant selective force affecting the expression of blood groups.Infectious Diseases And... · Rh Blood Groups And The... · Malaria: Evidence For...
[31]
A General Model of Negative Frequency Dependent Selection ...
Using knowledge of ABO protein function, we generated a simple model of asymmetric negative frequency dependent selection and genetic drift to explain the ...
[32]
Negative frequency dependent selection unites ecology and evolution
Jul 20, 2023 · Negative frequency dependent selection occurs when an increase in relative abundance is accompanied by a decrease in absolute fitness (panel a).NEGATIVE FREQUENCY... · MECHANISMS OF NFDS · ALTERNATIVES TO NFDS
[33]
Multiplicative fitness, rapid haplotype discovery, and fitness decay ...
Jun 21, 2019 · The first, negative frequency-dependent selection, is thought to be driven by the ability of rare MHC alleles to provide better protection ...
[34]
A sequence-based approach demonstrates that balancing selection ...
Negative frequency-dependent selection has also been proposed as a model of balancing selection that could maintain HLA diversity (15,29). Also referred to ...
[35]
The influence of genetic drift on the formation and stability of ...
Feb 21, 2016 · Highlights. We determine the effects of genetic drift on negative frequency-dependent selection. The stable polymorphism of an infinite ...Missing: robustness migration
[36]
Local negative frequency-dependence can decrease global ... - NIH
We find that, under sufficient fragmentation and low enough migration, local negative frequency-dependent (NFD) selection can reduce global coexistence, ...
[37]
Dynamics of Positive Frequency Dependent Selection Triggers ...
Apr 18, 2022 · Positive frequency dependent selection is a natural selection ... rapid fixation within the population. It must be noted that one of ...
[38]
Female mating preference functions predict sexual selection against ...
May 28, 2008 · Cichlid fish in African lakes have sustained high rates of speciation despite evidence for widespread hybridization, and sexual selection by ...
[39]
Frequency-Dependent Selection Predicts Patterns of Radiations and ...
First, we predict that whether the rate of speciation will remain constant or decline over time depends on the addition of frequency-dependent selection.
[40]
EVIDENCE FOR NEGATIVE FREQUENCY‐DEPENDENT SELECTION DURING EXPERIMENTAL COEVOLUTION OF A FRESHWATER SNAIL AND A STERILIZING TREMATODE
**Summary of Evidence for Negative Frequency-Dependent Selection (FDS) in Snail-Trematode System**
[41]
Negative frequency dependent selection on plasmid carriage and ...
Nov 20, 2019 · Negative frequency dependent fitness can contribute to maintaining a stable frequency of resistance genes in the absence of selection pressure ...
[42]
When does antimicrobial resistance increase bacterial fitness ...
Apr 20, 2024 · This group-level protective effect allows wild-type cells to act as “cheats”, leading to fitness that is negatively frequency-dependent ( ...<|control11|><|separator|>