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Shots

Shots, commonly referring to medical injections, involve the administration of liquids such as , medications, or nutrients into the body using a and , bypassing the digestive system for rapid or targeted delivery. This method, refined in the following early syringe prototypes from the , enables intramuscular, subcutaneous, intravenous, or other routes depending on the substance and therapeutic goal. In , shots have achieved landmark successes through campaigns, eradicating globally and averting an estimated 154 million deaths worldwide since 1974, predominantly among children under five.00850-X/fulltext) Peer-reviewed analyses confirm high efficacy against targeted pathogens, with routine immunizations reducing disease incidence by orders of magnitude and yielding substantial net benefits in lives and life-years saved when risks are empirically assessed. However, shots are not devoid of risks; clinical data document adverse events ranging from mild local reactions to rare severe outcomes, including , neurological complications, and, in mRNA vaccines, elevated incidence among young males. Controversies persist around shot safety and policy, fueled by historical incidents like contaminated polio vaccines and ongoing debates over mandates, ingredient concerns (e.g., adjuvants), and unsubstantiated causal links to conditions like —claims refuted by large-scale epidemiological studies yet amplified by selective reporting and institutional trust erosion. Recent pharmacovigilance for shots has highlighted underreported signals for adverse events of special interest across global cohorts, underscoring the need for transparent risk-benefit analyses amid varying against transmission and variants. These tensions reflect broader causal considerations in weighing population-level benefits against individual harms, with empirical data guiding over coercive implementation.

Production

Development and Writing

"Shots!!!" was written by series co-creator Trey Parker, following the collaborative script development process typical of South Park, where Parker and Matt Stone outline stories emphasizing causal links between events using "therefore" or "but" to drive plot progression rather than mere "and" sequences. The episode's dual narratives—one centering on Randy Marsh's ethical lapses to boost Tegridy Farms sales to $300,000, the other on Liane Cartman's struggle to vaccinate a needle-phobic Eric Cartman—were conceived to satirize contemporaneous issues like cannabis industry compromises and rising anti-vaccination hesitancy amid 2019 measles outbreaks linked to unvaccinated clusters. This rapid ideation aligns with South Park's six-day production cycle, enabling writing to occur mere days before the October 9, 2019, airing as the series' 300th episode, prioritizing timeliness over extended revision. Parker's script credits reflect his primary authorship role, though Stone's input shapes the irreverent tone critiquing both parental indulgence and pseudoscientific exemptions without endorsing unsubstantiated fears. The writing avoids moral equivocation, portraying vaccination evasion as irrational self-interest, grounded in empirical public health data showing herd immunity thresholds unmet due to opt-outs.

Animation and Direction

"Shots!!!" was directed by , co-creator of , who oversees the visual storytelling and pacing in most episodes of the series. Parker's direction emphasizes quick cuts, exaggerated character movements, and satirical visual gags, aligning with the episode's dual subplots involving ' expansion and resistance to vaccinations. The animation process utilized the show's proprietary digital system, which simulates traditional cutout paper techniques through scanned assets manipulated in software like and custom tools, enabling the production of 22-minute episodes in under a week. This method, refined since the series' early seasons, prioritizes efficiency—rendering up to 30 shots per hour on a dedicated farm—while maintaining the intentionally crude, flat aesthetic that distinguishes from more polished . No significant deviations from this standard workflow were reported for "Shots!!!", allowing focus on thematic content over experimental visuals.

Plot

Tegridy Farms Subplot

In the subplot of the South Park episode "Shots!!!", aired on October 9, 2019, celebrates achieving $300,000 in profits from his marijuana business, primarily derived from sales to the Chinese government as established in the prior episode "". organizes extravagant festivities, including a and , to mark the milestone, while attempting to reframe the enterprise's success as a collective family accomplishment despite prior familial opposition to his relocation and business pursuits. Randy's family, including , , and , expresses deepening resentment toward his ethical compromises, particularly the sale of to —where marijuana remains illegal and is reportedly used to incarcerate political dissidents—viewing the profits as tainted and emblematic of Randy's prioritization of financial gain over principles. Efforts by Randy to reconcile through material gestures, such as purchasing luxury items to symbolize shared prosperity, fail to alleviate tensions, exacerbating the family's alienation and highlighting ongoing discord stemming from the venture's inception in season 22. The narrative intersects with the main plot when , displaced after her son Eric evicts her, seeks temporary refuge at . bonds with Liane over a shared , confiding in mutual parental frustrations, which prompts him to reconnect with , the anthropomorphic towel who had departed the farm earlier in the season. Towelie counsels against continued aggression toward local homegrown marijuana operations and dependence on Chinese markets, urging a return to authentic, principled farming. Influenced by this advice, publicly rejects the Chinese partnership, declaring "fuck the Chinese government" and committing to cease competing growers, thereby restoring a degree of integrity to . rejoins the operation, signaling potential redemption for Randy's endeavor, though familial reconciliation remains tentative and sets the stage for subsequent developments in the storyline.

Vaccination Subplot

In the vaccination subplot of the South Park episode "Shots!!!", which aired on October 9, 2019, fourth-grader confronts mandatory immunizations enforced by his school, revealing that he has evaded vaccinations throughout his life due to an acute of needles. squeals and flees like a when pursued by medical authorities, prompting the town to hire a rural pig hunter equipped with lassos and tranquilizers to capture him. His mother, , initially accommodates his resistance by claiming conscientious objection and exploring exemptions, including a bizarre assertion that the might induce "artistic" traits in him, further highlighting his evasion tactics. Cartman escalates his opposition by invoking the debunked notion that vaccines cause autism, a claim originating from Andrew Wakefield's fraudulent 1998 study in The Lancet, which was retracted in 2010 amid ethical violations and falsified data, and contradicted by extensive epidemiological evidence showing no causal link. Despite these efforts, community pressure mounts, culminating in a sponsored "vaccine rodeo" event where vaccine-hesitant individuals, including Cartman and his classmates, are roped, hogtied, and forcibly administered injections amid their screams of terror, disregarding individual refusals in favor of herd immunity enforcement. In a twist, Liane intervenes during the rodeo chaos and receives an overdose of veterinary-grade intended for rather than humans, resulting in her exhibiting hyper-creative, artistic behaviors as a . This outcome allows Cartman to ostensibly receive his required off-screen, resolving the immediate school compliance issue while underscoring the subplot's portrayal of parental enabling and the physical coercion involved in mandates.

Themes and Analysis

Satire of Anti-Vaccination Sentiment

In the episode "Shots!!!", South Park satirizes anti-vaccination sentiment by centering the narrative on Eric Cartman's extreme aversion to immunization, portraying it as rooted in childish fear and pseudoscientific excuses rather than evidence-based concerns. Cartman, facing a school-mandated flu shot on October 9, 2019 (the episode's air date aligning with seasonal vaccination drives), fabricates claims about vaccines causing unrelated medical issues, echoing discredited theories such as the debunked link between MMR vaccines and autism originating from Andrew Wakefield's 1998 fraudulent study, which was retracted in 2010 after ethical violations and data manipulation were exposed. The episode depicts Cartman's evasion tactics—fleeing medical personnel and inciting chaos—as emblematic of broader anti-vaxxer irrationality, culminating in a "vaccination rodeo" where authorities pursue unvaccinated children, underscoring the public health disruptions caused by non-compliance. This portrayal aligns with empirical data affirming safety and , as large-scale studies, including those monitoring over 10 million doses, demonstrate that serious adverse events occur at rates below 1 in 1,000,000, far outweighed by the prevention of diseases like , which saw U.S. cases drop 99.9% post- rollout in 1963. Anti-vaccination claims, often amplified by theories, have been shown to correlate with lower vaccination rates and resurgent outbreaks, such as the 2019 U.S. with 1,282 cases linked to unvaccinated clusters, rather than substantiated risks. The episode's creators, and , use Cartman's archetype—a self-serving manipulator—to lampoon how personal phobias masquerade as principled opposition, critiquing the movement's tendency to prioritize anecdotal fears over randomized controlled trials, like those for the reducing precursors by 88% in clinical evaluations. While the satire simplifies complex hesitancy drivers—such as rare side effects like Guillain-Barré syndrome (incidence ~1-2 per million doses)—it effectively highlights causal realism in : herd immunity thresholds, requiring 95% coverage for , collapse without widespread uptake, leading to preventable morbidity. Sources critiquing the episode, including mainstream reviews, note its pro- stance amid rising hesitancy (U.S. childhood vaccination rates dipped to 93% for MMR by 2019), but some conservative outlets argue it overlooks institutional overreach in mandates; however, peer-reviewed analyses confirm that anti-vax narratives, not regulatory biases, drive most refusals, with no systemic evidence of widespread vaccine harm beyond monitored signals. The humor's bite lies in exposing the anti-vax position's empirical weakness, as meta-analyses of over 138 studies refute causation, attributing persistence to rather than data.

Critique of Ethical Compromises in Business

In the subplot of "Shots!!!", aired October 9, 2019, exuberantly commemorates his marijuana business achieving $300,000 in sales, framing it as a triumphant milestone despite underlying moral lapses that alienate his wife . She explicitly condemns the "unethical deals" underpinning this profit, revealing Randy's willingness to bend principles—exemplified in the episode's absurd escalation to acts like the fictional slaying of a analogue—to meet aggressive revenue targets. This portrayal underscores a satirical lens on entrepreneurial pursuits where short-term gains eclipse integrity, with Randy's unrepentant glee contrasting the familial discord it provokes. The episode critiques how businesses cloak ruthless pragmatism in narratives of wholesome innovation, as evolves from a purportedly principled operation into a profit-driven entity indifferent to collateral ethical costs. Reviewers noted this as a jab at capitalism's underbelly, where milestones like Randy's ,000 haul symbolize broader incentives for executives to rationalize compromises, from exploitative partnerships to disregard for stakeholders, under the guise of "providing for ." Such dynamics mirror real-world cases where corporate leaders prioritize quarterly earnings over sustainable practices, as evidenced by historical scandals involving falsified metrics or harmful supply chains, though the show amplifies this via to expose the causal chain from ethical shortcuts to relational and reputational erosion. This thematic thread ties into South Park's recurring examination of authority figures' hypocrisies, positioning Randy's arc as a caution against unchecked ambition that erodes personal bonds and . Sharon's disapproval manifests in outright rejection of the farm's "," highlighting how ethical compromises, once normalized for profit, propagate dysfunction beyond balance sheets— a point reinforced by the subplot's resolution where family unity fractures under the weight of Randy's moral trade-offs. The avoids prescribing solutions but empirically illustrates the incentives: in a competitive , ethical adherence risks , yet deviation invites backlash, as seen in subsequent Tegridy episodes where similar shortcuts invite external scrutiny.

Broader Commentary on Parental Responsibility and Authority

The "Shots!!!" portrays parental through Liane Cartman's initial defense of her son against mandatory , as community members and school officials intervene to enforce after discovering he has never received routine shots. This dynamic highlights Liane's exercise of parental to Cartman from perceived harm, yet the narrative frames her longstanding failure to vaccinate him as a lapse contributing to his and the ensuing chaos, including a farcical pursuit reminiscent of hog-tying. By depicting Liane's protectiveness as ultimately yielding to external pressure, the satirizes how parental indulgence of unfounded fears can perpetuate risks, implying that entails proactive based on established medical protocols rather than to a child's phobias. In a broader context, the storyline underscores parental responsibility as rooted in of , where failure to immunize children not only endangers the individual—evidenced by historical data showing pre- eras with annual U.S. cases exceeding 500,000 and over 400 deaths—but also undermines thresholds of 90-95% coverage needed to prevent outbreaks. Studies confirm that unvaccinated clusters, often stemming from parental opt-outs, have fueled resurgent epidemics, such as the 2019 U.S. outbreak with 1,282 cases linked to under-vaccinated communities, demonstrating causal links between hesitancy and preventable morbidity. While parental rights to are enshrined in frameworks like the U.S. Supreme Court's upholding of state mandates in (1905), the episode's lens aligns with causal realism: parents wield authority as stewards, obligated to prioritize verifiable benefits over anecdotal or ideologically driven exemptions that amplify societal costs. This commentary extends to critiques of systemic influences on decision-making, where media amplification of rare adverse events—despite peer-reviewed meta-analyses affirming no causal association between and conditions like —can erode parental discernment, favoring emotional appeals over longitudinal safety data from millions of doses. The episode implicitly advocates for grounded in first-principles evaluation of risks, where diseases' high (e.g., pertussis fatality rates up to 1% in infants) dwarfs vaccine side effects occurring in fewer than 0.01% of cases, urging parents to navigate with toward biased narratives from advocacy groups rather than deferring to institutional defaults without scrutiny. Real-world legal precedents, such as courts overriding parental refusals in life-threatening scenarios, reinforce that is conditional on non-maleficence, balancing with to evidence.31255-7/fulltext)

Reception

Critical Reviews

Critics offered mixed assessments of "Shots!!!", the 300th episode of , which aired on October 9, 2019, praising its sharp satire of anti-vaccination rhetoric while critiquing its failure to deliver a landmark anniversary spectacle. assigned an A grade, commending the episode for surpassing recent installments through inventive humor, particularly the "vaccination rodeo" sequence that lampooned campaigns and parental denialism, though it noted the subplot with felt underdeveloped compared to the main storyline. Den of Geek described the episode as a return to form after a weaker , appreciating how it dismantled Cartman's pseudoscientific excuses for avoiding shots—such as unsubstantiated claims of or lost creativity—by tying them to his manipulative schemes, ultimately reinforcing for safety through the plot's resolution where unvaccinated children face . However, the faulted the narrative for relying on familiar tropes without elevating the status, suggesting the dual plotlines diluted focus. Aggregate critic sentiment on reflected this ambivalence for Season 23 overall, with a 50% score across six reviews, where "Shots!!!" drew specific ire for underwhelming as an event despite comedic highs in the anti-vax mockery, such as the rodeo's absurd incentives like free tacos to boost compliance rates. One reviewer argued the Tegridy arc, centered on Randy's hemp , lacked punch and overshadowed the sharper critique, which effectively exposed causal fallacies in hesitancy arguments like equating to causation in rare adverse events. Outlets like CBR ranked it highly within the season for demonstrating restraint in , avoiding overkill by letting debunked anti-vax claims self-destruct via Cartman's exposure rather than heavy-handed preaching, aligning with data from sources like the CDC showing ' overwhelming profile in preventing outbreaks. Conversely, some critiques, including IMDb's sparse professional feedback, echoed user sentiments that the episode prioritized topical jabs over cohesive storytelling, with the 300th installment's modest 0.95 million viewers underscoring perceived lack of ambition.

Audience and Viewer Reactions

The episode "Shots!!!" received a 7.5 out of 10 rating on from over 2,600 user votes, reflecting generally favorable viewer sentiment among the platform's audience. Many users praised the episode's humor and its pointed of anti-vaccination arguments, with comments highlighting Cartman's portrayal as a self-serving coward whose refusal to vaccinate endangers others as an effective takedown of motivated by fear or . However, a subset of low ratings, including several 1-star reviews, appeared to stem from viewers offended by the depiction of anti-vaxxers, with some reviewers explicitly criticizing the episode for oversimplifying or mocking legitimate concerns about . On Reddit's r/southpark community, post-episode discussions revealed mixed reactions, with users appreciating the balance between mocking anti-vaxx rhetoric—such as Cartman's pseudoscientific excuses—and acknowledging parental instincts to protect children from disease outbreaks. Some viewers found the subplot with Randy Marsh's crass commercialization detracted from the main storyline, describing the episode as "bland" or overly reliant on recurring gags, though others defended it as a solid entry that advanced season-long arcs. Anti-vaxx sympathizers in these threads often missed the satirical intent, interpreting the episode as inadvertently validating their views by showing school mandates as authoritarian, despite the narrative's clear condemnation of unvaccinated individuals sparking outbreaks. Viewer polarization was evident in broader online discourse, where the episode's critique of vaccine avoidance—framed as irrational fear rather than evidence-based skepticism—drew ire from communities prone to hesitancy, who viewed it as pro-mandate ignoring potential side effects or overreach. In contrast, pro- audiences lauded the episode for using Cartman's selfishness to underscore herd immunity's importance, with reactions emphasizing empirical realities like resurgence tied to declining vaccination rates in unvaccinated clusters. No widespread organized backlash or emerged, unlike more incendiary installments, but the theme contributed to the show's reputation for eliciting defensive responses from ideologically invested viewers.

Controversies and Debates

Portrayal of Vaccine Hesitancy

In the episode "Shots!!!" aired on October 9, 2019, is depicted through Cartman's vehement refusal to receive required vaccinations for attendance, portraying it as rooted in personal cowardice rather than ideological conviction. Cartman, the only unvaccinated child at Elementary, disrupts medical visits by squealing and fleeing like a "greased pig," forcing his mother Liane to chase him repeatedly. This behavior escalates to threats of expulsion, prompting Cartman to feign anti-vaccine arguments by reciting scripted concerns about immunizations causing or making him "artistic," a of common hesitancy tropes. However, the episode reveals these claims as insincere pretexts, with Cartman's true motivation being an irrational fear of needles and mild pain, underscoring hesitancy as selfish avoidance rather than evidence-based skepticism. The narrative frames institutional enforcement positively, with school principal PC Principal upholding vaccination mandates as non-negotiable for and access. Cartman's attempt to claim status fails, highlighting the limits of individual exemptions in the show's universe. The subplot culminates in a "vaccine rodeo," a comedic public spectacle sponsored by a pharmaceutical company where townsfolk pursue and restrain Cartman to administer the , satirizing resistance as a disruptive spectacle warranting communal intervention. This resolution reinforces vaccination compliance, with Cartman ultimately vaccinated, implying hesitancy yields to authority and without altering policy. Critics noted the portrayal's pointed mockery of the anti-vaccine movement, associating hesitancy with Cartman's signature immaturity and manipulation rather than legitimate parental concerns over rare adverse events or over-scheduling. The episode aired amid rising U.S. outbreaks linked to declining rates, which fell to 91.1% for kindergartners in 2018-2019 from prior highs, contextualizing the satire against real-world debates. By conflating genuine with broader hesitancy, the depiction dismisses nuanced objections, prioritizing and mandate adherence over individual autonomy.

Oversimplification of Public Health Mandates

The episode portrays mandates through the lens of a rigid school policy requiring full for enrollment, enforced by PC Principal with the assertion that deviation "puts everyone at risk." This framing emphasizes principles, aligning with U.S. policies where all 50 states mandate vaccines like MMR for school attendance to prevent outbreaks, as evidenced by a 99% reduction in cases since widespread adoption in the 1960s. Critics have argued that this depiction oversimplifies mandates by reducing opposition to Cartman's cartoonish phobia of needles, ignoring substantive concerns such as rare adverse events documented in systems like VAERS, where reports of serious injuries, though unverified and representing less than 0.01% of doses administered, fuel hesitancy debates. The narrative's use of a religious exemption loophole exploited by Cartman satirizes evasion tactics but neglects philosophical exemptions allowed in 15 states, potentially reinforcing a binary view of compliance versus without of how mandates influence long-term adherence rates. The resolution, culminating in a "vaccine rodeo" chase and Liane Cartman's accidental overdose transforming her behavior, highlights enforcement absurdities but elides ethical tensions, including bodily versus collective —a tension underscored by legal precedents like (1905), which upheld mandates during epidemics yet required consideration of individual peril. Post-2019 reflections, amid mandate backlash, have amplified claims that such episodes contributed to public discourse oversimplifying policy trade-offs, as evidenced by declining institutional trust polls showing confidence dropping from 88% in 2019 to 69% by 2023 among U.S. parents. This approach has been contrasted with more nuanced critiques in later South Park specials, where mandate enforcement is shown eroding community cohesion, suggesting the original episode's pre-pandemic context limited its engagement with real-world causal factors like variant-driven breakthrough infections or exemption clustering leading to localized outbreaks despite high national coverage.

Legacy

Significance as the 300th Episode

"Shots!!!" aired on October 9, 2019, as the third episode of South Park's twenty-third season and the 300th episode overall in both production and broadcast order. The milestone was acknowledged within the narrative through Randy Marsh's exuberant celebration of Tegridy Farms achieving $300,000 in sales, a figure that mirrors the episode count without disrupting the show's standard structure. This integration allowed creators Trey Parker and Matt Stone to forgo traditional anniversary tropes like clip montages or elaborate retrospectives, opting instead for the series' characteristic dual-plot format centered on contemporary social issues. The decision to embed the 300th episode marker into an ongoing storyline —Randy's self-aggrandizing farm promotion—highlighted South Park's preference for satirical continuity over milestone exceptionalism, even as the main plot lampooned via Eric Cartman's refusal to receive required immunizations. Official promotional materials from emphasized the episode as the "300th," framing it around themes of in , with Cartman's fear of shots potentially inducing "artistic" side effects tying into broader anti-vaxxer parodies. This approach maintained the series' rapid production cycle, which enables episodes to air shortly after conception, underscoring how South Park prioritizes topical relevance—such as ongoing debates over mandatory vaccinations—over commemorative . Reviews noted the subdued handling of the anniversary, with some observers critiquing the episode's modest scale compared to prior milestones like the 200th, which featured more interconnected storytelling; IGN described it as lacking the "epic anniversary celebration" potentially warranted by the longevity, rating it 6/10 for its parallel but unmerged plots. Others, including The A.V. Club, praised the restraint as fitting the show's ethos, calling it a "strong 300th episode" for blending humor with pointed commentary on parental choices and public health without pandering to expectations of grandeur. The milestone thus exemplified South Park's endurance, having sustained weekly output since 1997, but also invited discourse on whether the format's consistency sometimes underserves numerical benchmarks in a landscape dominated by more event-driven anniversaries.

Influence on Later South Park Vaccine Satire

The "Shots!!!" episode, aired on October 2, 2019, established a satirical framework in for critiquing by depicting parents exploiting pseudoscientific fears for financial gain and children like Cartman fabricating injuries to avoid , ultimately affirming the necessity of routine vaccinations amid school mandates. This approach influenced subsequent episodes by providing a blueprint for amplifying absurdities in debates, shifting from general anti-vaccine tropes to pandemic-specific chaos without abandoning the core ridicule of obstructionists. In the "," premiered March 10, 2021, creators and extended this to the rollout, portraying residents clamoring for doses amid shortages, line-cutting by celebrities and elites, and militant groups—echoing QAnon-inspired conspiracists—attempting to sabotage distribution sites, including efforts to block the boys from vaccinating their teacher. The special reused elements from "Shots!!!," such as the character Big Mesquite Murph, a holdover anti- figure, to link the pre-pandemic mockery of hesitancy with real-time absurdities like envy and bureaucratic frustrations, maintaining 's pattern of highlighting self-interested hypocrisies on all sides while underscoring vaccines' role in restoring normalcy. This evolution reflects and Stone's stated to derive humor from timely societal frictions rather than ideological , as they described writing such episodes simply because "we think it's funny," allowing "Shots!!!" to prefigure a broader critique of how imperatives expose underlying opportunism and division, themes reprised in COVID-era content without resolving into unambiguous endorsement or condemnation. The specials' focus on logistical mayhem and conspiracy-driven resistance, rather than outright rejection of , demonstrates a in using to probe causal breakdowns in , informed by empirical rollout challenges like supply inequities documented in early 2021.

References

  1. [1]
    Definition of injection - NCI Dictionary of Cancer Terms
    (in-JEK-shun) Use of a syringe and needle to push fluids or drugs into the body; often called a shot.
  2. [2]
    Injection Types & Sites: What you need to know - Drugs.com
    Nov 2, 2021 · An injection is a way of administering a liquid to a person using a needle and syringe. It's also sometimes also called a 'shot' or 'jab'.<|separator|>
  3. [3]
    A history of syringes and needles - Faculty of Medicine
    Dec 20, 2018 · In 1650, Pascal's experimental work in hydraulics stimulated him to invent the first modern syringe which allowed the infusion of medicines.
  4. [4]
    A history of injection treatments - I the syringe - PubMed
    The syringe has long been used for aspiration, irrigation and infusion. This developed into injections for early transfusion, anaesthesia and surgical ...
  5. [5]
    A Brief History of Vaccination - World Health Organization (WHO)
    For over 2 centuries, people have been vaccinated against deadly diseases, ever since the world's first vaccine was devised against smallpox.
  6. [6]
    Evidence Summary - Safety of Vaccines Used for Routine ... - NCBI
    Considered one of the greatest public health achievements, vaccines are effective in controlling the spread of and even eradicating a variety of infectious ...
  7. [7]
    Lives and life-Years Saved From COVID-19 Vaccination
    Findings This comparative effectiveness study found that COVID-19 vaccinations averted 2.5 million deaths during 2020-2024 (sensitivity range estimates, 1.4-4.0 ...
  8. [8]
    COVID-19 vaccines and adverse events of special interest
    Apr 2, 2024 · This study aimed to evaluate the risk of adverse events of special interest (AESI) following COVID-19 vaccination from 10 sites across eight countries.
  9. [9]
    Vaccine Efficacy, Impact, Hesitancy, and Acceptance
    Apr 11, 2024 · Vaccines are indispensable tools in the battle against infectious diseases and hold great potential in combating a myriad of other diseases.
  10. [10]
    Principal Controversies in Vaccine Safety in the United States
    Aug 1, 2019 · Concerns about vaccine safety can lead to decreased acceptance of vaccines and resurgence of vaccine-preventable diseases.Missing: surrounding shots
  11. [11]
    Current controversies in childhood vaccination - PubMed
    Controversies regarding vaccine components and side effects have misled parents to believe that vaccines might be harmful based on inaccurate data.Missing: shots | Show results with:shots
  12. [12]
    Controversies in vaccine mandates - PubMed
    Policies that mandate immunization have always been controversial. The controversies take different forms in different contexts.Missing: surrounding shots
  13. [13]
    Scrutinizing the COVID-19 vaccine safety debate - PubMed
    Dec 31, 2024 · A 2024 study suggests a potential link between COVID-19 vaccinations and adverse outcomes, emphasizing the importance of thorough scientific investigation.
  14. [14]
    How Trey Parker and Matt Stone Write 'South Park' | No Film School
    That pilot was shot on 35mm film and took three months to make. Now they finish shows in a week. That's progress! What are some of the best things you ...
  15. [15]
    "South Park" Shots!!! (TV Episode 2019) - IMDb
    Rating 7.5/10 (2,610) Randy revels in a Tegridy Farms milestone; Cartman stands his ground and refuses to get a shot.
  16. [16]
    Animating South Park with Jack Shih - Peter McGraw
    Sep 11, 2019 · Jack Shih is an Emmy Award-winning animation director and producer known most notably for his work on South Park. ... shots look like, giving them ...
  17. [17]
    Behind the Scenes of South Park's Animation: A Look into ... - Ask.com
    May 19, 2025 · The show's unique cutout animation style is achieved by taking photographs of construction paper cutouts and importing them into the software.Missing: S26E02 | Show results with:S26E02
  18. [18]
    Season 23, Ep. 3 - SHOTS!!! - Full Episode | South Park Studios Global
    Oct 9, 2019 · South Park. SHOTS!!! Season 23 E 3 • 10/09/2019 ... Randy celebrates the success of Tegridy Farms while Cartman refuses to get a shot.Missing: animation | Show results with:animation
  19. [19]
    South Park has a vaccination rodeo, and Randy tries to get his ...
    Oct 10, 2019 · South Park has a vaccination rodeo, and Randy tries to get his Tegridy back in a strong 300th episode.
  20. [20]
    South Park Season 23 Episode 3 Review: SHOTS | Den of Geek
    Oct 10, 2019 · In “SHOTS,” the honeymoon period of living on the farm completely shatters. Randy wants to position Tegridy's success as a family one, and the ...Missing: summary | Show results with:summary
  21. [21]
    'South Park' (300th Episode) Review: 'Shots' Fires Back At The Anti ...
    Oct 10, 2019 · Cowardly Cartman is shown to have never, ever accepted the mild pain of a vaccination shot, meaning he briefly faces expulsion from school.
  22. [22]
    South Park Episode 300: "Shots!!!" Review - IGN
    Rating 6/10 · Review by Jesse SchedeenOct 10, 2019 · It's more that "Shots!!!" is a disjointed episode with two plot threads that barely have any relation to one another. And while this episode's ...
  23. [23]
    Shots!!! - South Park Wiki
    Shots!!! Season, s23. Episode, e03. Written By, Trey Parker. Production Code ...
  24. [24]
    'South Park' to Celebrate 300th Episode With Anti-Vaxxer Story
    Oct 7, 2019 · In a short preview from “SHOTS!!!” Cartman refuses to get a flu shot, arguing the false theory it could lead to other medical issues. As if the ...Missing: plot | Show results with:plot
  25. [25]
    Anti-vax: the history of a scientific problem - PMC - NIH
    ... empirical evidence confirming the efficacy of the vaccines. Innumerous challenges remain that are not only related to the vaccine production, supply and ...
  26. [26]
    Vaccine Safety: Examine the Evidence - HealthyChildren.org
    Nov 21, 2024 · Research continues to confirm that vaccines are safe and effective—and they protect children and teens from serious diseases. How we know that ...Missing: key | Show results with:key
  27. [27]
    The Effects of Anti-Vaccine Conspiracy Theories ... - Research journals
    Results revealed a significant negative relationship between anti-vaccine conspiracy beliefs and vaccination intentions.
  28. [28]
    [PDF] Update on CDC's COVID-19 Vaccine Safety Monitoring
    Jun 25, 2025 · Co-managed by CDC and FDA. • Nationwide spontaneous reporting system that can rapidly detect safety signals, including rare events.<|control11|><|separator|>
  29. [29]
    Estimating the size of “anti-vax” and vaccine hesitant populations in ...
    Mar 29, 2022 · The Strong Support and Support with Concerns classes broadly view COVID-19 vaccines as effective, while the Anti-Vax see them as ineffective.
  30. [30]
    South Park S 23 E 3 Shots Recap - TV Tropes
    Oct 9, 2019 · Randy celebrates earning $300,000 through Tegridy sales, and Sharon disapproves of the unethical deals he made to get the money. Meanwhile, ...
  31. [31]
    Season 23 – South Park - Rotten Tomatoes
    Rating 50% (6) "Shots!!!" isn't really the epic anniversary celebration South Park deserved... While this episode's vaccine rodeo antics offered plenty of laughs, the Tegridy ...
  32. [32]
    South Park: Every Episode In Season 23, Ranked - CBR
    Jan 20, 2021 · The idea that less can be more isn't always South Park's MO, but "Shots!!!" is an example of the series exhibiting some restraint and taking ...<|separator|>
  33. [33]
    "South Park" Shots!!! (TV Episode 2019) - User reviews - IMDb
    So, this is the big 300th episode. I know it would be hard to top the 200th and 201st episodes, seeing as how they were literally threatened about it. The ...
  34. [34]
    South Park, Season 23 Episode 3 - “Shots!!!” Review : r/southpark
    Dec 21, 2019 · This episode parodies the anti-vaccine movement and also celebrates its 300th episode. In the episode, Liane Cartman finds it incredibly difficult to vaccinate ...S23, Episode 3 "Shots!!!" Review : r/southpark - RedditPost Episode Discussion: S23E3 - "SHOTS!!!" : r/southpark - RedditMore results from www.reddit.comMissing: summary | Show results with:summary
  35. [35]
    South Park: Cartman Takes On the Anti-Vax Movement - CBR
    Oct 21, 2019 · South Park's 300th episode finds Eric Cartman in a very precarious position as Matt Stone and Trey Parker take shots at the Anti-Vaxxer ...
  36. [36]
    South Park - We can't even risk a .1% chance of vaccination making ...
    Oct 10, 2019 · We can't even risk a .1% chance of vaccination making our children artistic. Watch our 300th episode "SHOTS!!!" now - cart.mn/sp-2303
  37. [37]
    'South Park' Celebrates 300th Episode By Poking Fun At Anti-Vaxxers
    Oct 7, 2019 · South Park is celebrating its 300 th episode by poking fun at the anti-vaxxer movement. This comes as the Comedy Central series has reportedly been scrubbed ...Missing: title | Show results with:title
  38. [38]
    'South Park' Mocks QAnon, Vaccine Line-Cutters in Hourlong
    Mar 10, 2021 · ... Trey Parker and Matt Stone just had to address before the series' usual fall run. The South ParQ: Vaccination Special (simulcast on MTV2 ) ...
  39. [39]
    "South Park" South ParQ Vaccination Special (TV Episode 2021)
    Rating 7.5/10 (4,205) The citizens of South ParQ are clamoring for the COVID-19 vaccine. A hilarious new militant group tries to stop the boys from getting their teacher vaccinated.Missing: 2012 | Show results with:2012
  40. [40]
    Season 24, Ep. 2 - South ParQ Vaccination Special - Full Episode
    Nov 6, 2019 · The citizens of South ParQ are clamoring for the COVID-19 vaccine. A hilarious new militant group tries to stop the boys from getting their teacher vaccinated.
  41. [41]
    South Park's most notable controversies | The Independent
    Mar 11, 2021 · South Park has become synonymous with controversy. With a backlog of more than 308 episodes, the show has made headlines for a variety of reasons over the ...
  42. [42]
    South Park Comments on Vaccinations in New Special - BC Heights
    Mar 26, 2021 · The episode critiques the difficulty of receiving a COVID-19 vaccine and lampoons the U.S. Capitol rioters as well as members of the extremist ...
  43. [43]
    'South Park Vaccination Special' Review: Comedy in Crisis - IndieWire
    Mar 11, 2021 · Matt Stone and Trey Parker's "South Park Vaccination Special" argues there's no pretending a post-pandemic world can just go back to normal.<|separator|>