Cardinal Health
Cardinal Health, Inc. is a multinational healthcare services and products company headquartered in Dublin, Ohio, specializing in the distribution of pharmaceuticals and medical supplies to hospitals, pharmacies, health systems, and ambulatory surgery centers.[1][2] Founded in 1971, the company employs approximately 48,000 people and operates as a key player in the U.S. healthcare supply chain, focusing on cost-effective solutions that enhance efficiency for providers while supporting patient care.[3][4] The firm's primary business segments include Pharmaceutical and Specialty Solutions, which manages the distribution of generic, branded, and specialty pharmaceuticals along with nuclear pharmacy services, and Global Medical Products and Distribution, encompassing the manufacture and supply of gloves, surgical apparel, and laboratory products.[5][6] In fiscal year 2025, Cardinal Health generated revenues of $222.6 billion, reflecting its scale as a leading distributor serving diverse healthcare needs amid ongoing supply chain complexities.[7] Notable for its operational efficiencies and market position, Cardinal Health has pursued strategic portfolio reviews to streamline operations, including divestitures and focus on high-growth areas like specialty pharmaceuticals.[8] However, the company has encountered controversies, particularly regarding its historical distribution practices, leading to multimillion-dollar settlements in opioid-related litigation, such as a $152.5 million resolution with the City of Baltimore in 2024 over alleged failures in monitoring suspicious orders.[9] These legal outcomes underscore challenges in regulatory compliance within pharmaceutical distribution.[10]Company Profile
Founding and Corporate Evolution
Cardinal Health was founded on April 1, 1971, as Cardinal Foods by Robert D. Walter, who acquired the struggling Monarch Foods, a regional grocery distributor in Columbus, Ohio, through a leveraged buyout with a small group of investors.[11][12] Initially focused on food wholesaling, the company operated a small distribution center and expanded regionally within its first decade, achieving moderate success in a competitive market.[13] The pivotal shift to healthcare occurred in 1979, when Cardinal Foods purchased Bailey Drug Company, a modest pharmaceutical wholesaler in Zanesville, Ohio, marking its entry into drug distribution amid growing demand for specialized supply chains.[13][11] This acquisition prompted the divestiture of non-core food operations and a rebranding of the pharmaceutical division to Cardinal Distribution, Inc. in 1980, followed by its initial public offering on the NASDAQ in 1983 under the ticker CARD.[14] By the mid-1980s, pharmaceutical distribution had become the core business, with early successes in serving independent pharmacies and hospitals driving revenue growth from under $100 million in 1984 to over $1 billion by 1990.[11] Corporate evolution accelerated in the 1990s through aggressive acquisitions that diversified into pharmacy services, manufacturing, and medical products, including Medicine Shoppe International in 1995 for retail pharmacy expansion and R.P. Scherer Corporation in 1998 for pharmaceutical packaging capabilities.[15] The company adopted the Cardinal Health name in 1994 to reflect its health-focused identity and relocated headquarters to Dublin, Ohio, in 2000 to support national operations.[11] Subsequent decades saw further consolidation, such as the 2008 acquisition of Syncor International for nuclear pharmacy services and a 2014 spin-off of its specialty pharmaceutical manufacturing unit to Catalent Pharma Solutions, sharpening focus on distribution while navigating regulatory scrutiny.[15] By 2021, marking its 50th anniversary, Cardinal Health had become one of the largest U.S. pharmaceutical distributors, employing over 44,000 and generating $162 billion in fiscal 2020 revenue, primarily from its medical and pharmaceutical segments.[14]Business Segments and Operations
Cardinal Health structures its operations into two primary reportable segments—Pharmaceutical and Specialty Solutions, and Global Medical Products and Distribution—alongside other operating units including Nuclear and Precision Health Solutions, at-Home Solutions, and OptiFreight Logistics.[16][17] These segments enable the company to provide integrated healthcare services and products, distributing pharmaceuticals and medical supplies to hospitals, pharmacies, health systems, ambulatory surgery centers, and other providers across the United States, Canada, Europe, Asia, and other international markets.[18] With approximately 48,000 employees globally and operations in over 30 countries, the company supports supply chains serving about 90% of U.S. hospitals and 29,000 pharmacies worldwide.[2][19] The Pharmaceutical and Specialty Solutions segment, which generated $205 billion in revenue for fiscal year 2025, focuses on the distribution of branded and generic pharmaceuticals, over-the-counter products, and specialty pharmaceuticals to a network of retail and independent pharmacies, pharmacy chains, hospitals, and health systems.[20] This segment also offers third-party logistics services for pharmaceutical manufacturers, pharmacy management solutions, and support for specialty drug handling, including cold chain logistics and compliance with regulatory requirements for controlled substances.[16] Operations emphasize efficient supply chain management, with distribution centers strategically located to minimize delivery times and costs for customers.[1] The Global Medical Products and Distribution segment manufactures, distributes, and sells medical, surgical, and laboratory products, including single-use devices, apparel, gloves, and consumables used in patient care settings.[16] Key activities involve producing branded items such as fluid management systems and cardiology products under the Cordis name, alongside sourcing and distributing a broad portfolio of third-party medical supplies to acute care facilities and laboratories.[21] This segment supports operational efficiency in healthcare by providing customized kits, trays, and assembly services tailored to procedural needs.[1] Other operations encompass specialized services: Nuclear and Precision Health Solutions delivers radiopharmaceuticals and related imaging agents through a network of nuclear pharmacies; at-Home Solutions manages infusion therapies and direct-to-patient delivery for complex medications; and OptiFreight Logistics optimizes freight management for healthcare shipments.[17] These units contributed to the company's overall fiscal 2025 revenue of $222.6 billion, reflecting a focus on niche, high-value services amid broader supply chain challenges.[17]Historical Milestones
Early Years and Expansion (1971–1999)
Cardinal Health traces its origins to 1971, when Robert D. Walter, a 25-year-old Harvard Business School graduate, acquired the struggling Monarch Foods Company in Columbus, Ohio, through a leveraged buyout with investors and renamed it Cardinal Foods, initially operating as a regional food wholesaler and distributor.[11][14] The company focused on grocery distribution in the Midwest during its early years, building a foundation in logistics and supply chain management under Walter's leadership as founder and CEO.[11] In 1980, Cardinal Foods pivoted toward healthcare by acquiring a small drug distributor in Zanesville, Ohio, marking its entry into pharmaceutical wholesaling and prompting a rebranding to Cardinal Distribution, Inc., as food operations became secondary to the more profitable drug sector.[11][14] This shift capitalized on growing demand for efficient pharmaceutical supply chains, with the company expanding its distribution network through targeted acquisitions of regional drug wholesalers.[11] On August 4, 1983, Cardinal Distribution went public via an initial public offering on NASDAQ, raising capital at $1.03 per share to fuel further growth in pharmaceutical logistics.[14][22] By 1988, Cardinal fully divested its remaining food distribution assets, including Cardinal Foods and Midland Grocery, to Roundy's Inc. for $27 million, allowing revenues to surge by approximately one-third as resources concentrated on healthcare.[11] This strategic refocus propelled expansion in the 1990s, with revenues surpassing $1 billion by 1991 through acquisitions like Ohio Valley-Clarksburg in 1990 and Chapman Drug Co. in 1991, which extended its footprint into the Mid-Atlantic and Tennessee markets.[11] In 1994, the acquisition of Whitmore Distribution added $2.25 billion in annual sales, solidifying Cardinal as a national pharmaceutical powerhouse, while the purchase of Medical Strategies diversified into healthcare consulting; that year, the company rebranded as Cardinal Health, Inc., to reflect its broadened scope beyond mere distribution.[11] The late 1990s saw aggressive diversification via high-profile deals, including the 1995 acquisition of Medicine Shoppe International for $348 million in stock, enhancing retail pharmacy support services.[11] In 1996, Cardinal bought Pyxis Corporation for $870 million, entering automated medication management, and PCI Services, Inc., for $201 million, bolstering packaging capabilities.[11] The 1997 purchase of Owen Healthcare expanded hospital pharmacy management offerings, while 1998 brought R.P. Scherer for specialty pharmaceutical manufacturing despite a failed $4.5 billion bid for Bergen Brunswig blocked by the FTC over antitrust concerns.[11] Culminating the decade, the 1999 acquisition of Allegiance Corporation positioned Cardinal as a major medical-surgical products distributor, transforming it from a regional wholesaler into a multifaceted healthcare giant with integrated supply, manufacturing, and services.[11]Growth Era and Initial Challenges (2000–2019)
In the early 2000s, Cardinal Health capitalized on the expanding U.S. pharmaceutical distribution market, achieving record annual sales exceeding $25 billion by fiscal year 2000 through organic growth in its core wholesale operations and a series of strategic acquisitions that bolstered its medical and nuclear pharmacy segments.[12] Revenue continued to surge, reaching nearly $100 billion by fiscal 2009, a ninefold increase from 2000 levels, primarily driven by heightened demand for generic drugs, expansion into specialty pharmaceuticals, and efficiencies in supply chain logistics.[23] This period marked Cardinal's ascent as one of the largest healthcare distributors globally, with its Pharmaceutical segment accounting for the bulk of revenues amid broader industry consolidation and regulatory shifts favoring large-scale wholesalers.[24] By the mid-2010s, Cardinal pursued further diversification, acquiring AssuraMed in 2013 for an undisclosed sum to strengthen its at-home medical supplies portfolio, which contributed to sustained revenue expansion—reaching $127.2 billion in fiscal 2016 and climbing to $145.5 billion by fiscal 2019, reflecting a compound annual growth rate of approximately 12% over the decade.[25][26] The company also navigated structural changes, such as the 2010 spin-off of its proprietary drug manufacturing and packaging operations into Catalent Pharma Solutions, allowing focus on distribution and services while generating proceeds to reduce debt and fund core growth initiatives.[24] These moves positioned Cardinal as a dominant player, serving over 70% of U.S. hospitals and pharmacies, though they coincided with intensifying competition from peers like McKesson and AmerisourceBergen. Initial challenges emerged prominently in the distribution of controlled substances, as federal regulators, including the DEA, began scrutinizing Cardinal's practices for suspicious opioid shipments as early as 2007, leading to license revocations at select facilities and heightened compliance requirements.[27] By the 2010s, these issues escalated into multidistrict litigation, with lawsuits alleging failures to report and halt excessive orders from high-risk pharmacies, contributing to the broader opioid epidemic; for instance, a 2012 West Virginia case highlighted violations of controlled substances laws through inadequate due diligence.[27][28] Financial pressures mounted, culminating in a 2019 credit rating downgrade to 'BBB' by S&P Global due to potential multibillion-dollar liabilities from ongoing suits, alongside proposed settlements exceeding $10 billion among major distributors.[29][30] Despite implementing anti-diversion systems and education programs, these regulatory and legal headwinds strained operations and investor confidence, foreshadowing protracted resolutions into the next decade.[31]Modern Developments and Adaptations (2020–Present)
In response to the COVID-19 pandemic, Cardinal Health enhanced supply chain visibility and resiliency by implementing real-time data tracking for inventory and deliveries, while pivoting operations to prioritize personal protective equipment (PPE) and medical supplies, ensuring no facility closures during the crisis.[32][33] The company invested in advanced planning software, such as Kinaxis Rapid Response, to generate contingency options amid disruptions, marking a shift toward predictive supply chain management that persisted post-pandemic.[34] These adaptations addressed global shortages exacerbated by manufacturing outbreaks and demand surges, with lessons applied to broader healthcare logistics.[35] Cardinal Health participated in major opioid-related settlements to resolve distributor liability claims. In May 2022, it joined McKesson and AmerisourceBergen (now Cencora) in a $21 billion national agreement over 18 years with states, cities, and counties, aimed at abatement efforts through approximately April 2032.[36] Additional pacts included a $1.1 billion settlement with New York State in 2021 and a $300 million accord with U.S. health plans in August 2024, apportioned at 30.9% for Cardinal Health.[37][38] A related shareholder derivative suit settled for $124 million in 2022, addressing alleged failures in opioid distribution oversight.[39] To expand in specialty solutions, Cardinal Health pursued targeted acquisitions, including the Integrated Oncology Network in December 2024, a physician-led community oncology group, and Solaris Health in August 2025 for $1.9 billion, enhancing urology and radiation oncology services.[40][41] These moves supported growth in high-margin areas like cell and gene therapies, with the company issuing a 2025 report committing to commercialization amid rising demand.[42] Financially, revenues fluctuated due to contract changes and segment dynamics: fiscal year 2025 (ending June 30, 2025) totaled $222.6 billion, down 2% from $226.8 billion in fiscal 2024, though adjusted earnings per share rose amid raised guidance.[17] The Pharmaceutical segment drove most revenue at approximately $205 billion, with U.S. operations comprising over 99% of the total.[20] Quarterly reports in 2025 reflected resilience, with Q3 revenues flat at $54.9 billion and outlook elevations signaling optimism in specialty growth despite divestiture impacts.[43]Products and Services
Pharmaceutical Distribution
Cardinal Health's Pharmaceutical and Specialty Solutions segment manages the wholesale distribution of pharmaceuticals throughout the United States, supplying branded, generic (including repackaged generics), specialty drugs in therapeutic areas such as oncology, rheumatology, urology, and nephrology, over-the-counter products, consumer health items, and human-derived plasma products to healthcare providers.[5] This segment operates via a network of primary pharmaceutical and specialty distribution facilities, supplemented by a national logistics center, enabling services like inventory management, data analytics, patient support programs, and direct-to-point-of-care shipping for temperature-sensitive biopharmaceuticals.[5][44] The segment serves over 29,000 pharmacies (chain and independent), nearly 90% of U.S. hospitals, more than 6,200 clinical laboratories, approximately 10,000 specialty physician offices, ambulatory surgery centers, community health centers, and pharmaceutical manufacturers through group purchasing organization agreements.[45][5] Revenue concentration is notable, with CVS Health comprising 24% and OptumRx 17% of fiscal year 2024 segment revenue, underscoring reliance on large chain customers amid prime vendor contracts like the Red Oak Sourcing venture with CVS, extended through June 2029.[5] In fiscal year 2025, the segment generated $205 billion in revenue, forming the bulk of Cardinal Health's total $222.6 billion, driven by volumes in generic pharmaceuticals, specialty drugs including biosimilars and GLP-1 agonists, and brand inflation offset by occasional generic launches.[20][17] Segment profit reached $2.015 billion in fiscal year 2024, reflecting 7% year-over-year growth from improved generics performance and specialty sales.[5] Cardinal Health holds a substantial position in the U.S. pharmaceutical wholesale market, where it, McKesson, and Cencora collectively command about 95% share, facilitating efficient scale but exposing the industry to risks from supply disruptions, manufacturer pricing dynamics, and regulatory oversight on controlled substances.[46] Recent enhancements include the March 2024 acquisition of Specialty Networks for $1.2 billion, bolstering data, research, and access in specialty therapeutics.[5] The segment also supports biosimilars adoption through dedicated distribution channels and logistics tailored for complex supply chains.[47]Medical and Laboratory Products
Cardinal Health's Global Medical Products and Distribution segment manufactures and distributes a broad portfolio of medical and laboratory products, including clinician-preference items, cost-efficient consumables, and specialized equipment for healthcare facilities worldwide.[2] This segment supports hospitals, laboratories, and ambulatory settings with products designed to enhance operational efficiency and patient care, encompassing both proprietary Cardinal Health™ branded items and third-party offerings.[48] In fiscal year 2024, the company reported growth in sales of its Cardinal Health branded medical products, reflecting demand for reliable, value-driven solutions amid rising healthcare complexities.[5] The laboratory products lineup addresses needs across multiple disciplines, such as anatomic pathology, blood bank, clinical chemistry, hematology, microbiology, and general lab operations. Cardinal Health provides over 2,300 Cardinal Health™ Brand items, including Bio-Check® biohazard wipes, benchtop liners for spill containment, transfer pipets for precise liquid handling, in-line filters, pH indicator strips, and bibulous paper for absorption tasks.[49] [50] Laboratory equipment offerings feature centrifuges for sample separation, refrigerators for storage, and microscopes for analysis, sourced from leading manufacturers to ensure dependability in diagnostic and research workflows.[51] Additionally, the company supplies specimen collection kits and supports specialized testing, such as seasonal respiratory panels, through integrated distribution channels.[52] Medical products include surgical supplies and equipment, personal protective equipment like exam gloves and facial protection, infection control solutions, and durable medical equipment for patient mobility and care.[48] The portfolio extends to enteral feeding tubes and devices, anesthesia supplies, and original equipment manufacturer (OEM) specialty components customized to client specifications.[53] For at-home care, Cardinal Health distributes items in categories like incontinence products, wound care dressings, skin health aids, urology devices, and nutritional delivery systems, serving chronic condition management through a network of providers.[54] These offerings are backed by comprehensive catalogs exceeding 2,400 items, enabling streamlined procurement for end-users.[55]Legal and Regulatory Scrutiny
Opioid Distribution Practices and Resulting Litigation
Cardinal Health, as one of the largest pharmaceutical distributors in the United States, played a significant role in the supply chain for prescription opioids, shipping controlled substances from manufacturers to licensed pharmacies and hospitals while required under the Controlled Substances Act (CSA) to identify and report suspicious orders that could indicate diversion to illicit markets.[56] The company maintained a Controlled Substance Monitoring Program (CSMP) involving electronic order surveillance, customer risk assessments, and thresholds for reviewing orders exceeding certain volumes, with suspicious activity reported to the Drug Enforcement Administration (DEA).[57] However, federal enforcement actions revealed systemic shortcomings in these practices prior to enhanced reforms. Between 2008 and 2012, internal documents indicated Cardinal Health continued shipping unusually large volumes of opioids despite awareness of potential diversion risks, leading to a $44 million settlement with the DEA in December 2016 for alleged CSA violations, including failure to report suspicious orders from a Lakeland, Florida, distribution center that supplied pharmacies ordering millions of hydrocodone pills.[58] [59] In the same month, the company agreed to pay $34 million to resolve claims of inadequate record-keeping and unreported suspicious orders in its Kinray subsidiary's service area, where pharmacies exhibited patterns of excessive opioid purchases.[60] Additionally, a Cardinal Health unit settled for $10 million over failures to flag and report large orders of addictive opioids, highlighting gaps in monitoring high-risk customers.[61] These penalties stemmed from DEA audits showing unreported orders totaling hundreds of millions of dosage units, though Cardinal Health did not admit liability in the agreements.[58] In regions like Ohio, Cardinal Health distributed over one billion opioid pills between 2006 and 2014 to pharmacies serving populations far smaller than the shipment volumes warranted, contributing to allegations of inadequate due diligence in preventing over-distribution.[62] A 2018 Senate investigation further documented broader industry failures, including at distributors like Cardinal, where reporting systems repeatedly overlooked red flags such as rapid order escalations and pharmacy clustering in opioid hotspots.[63] These practices triggered extensive civil litigation, primarily through multidistrict opioid lawsuits filed by states, counties, and municipalities accusing Cardinal Health of prioritizing sales over regulatory duties, thereby fueling the opioid epidemic.[64] In February 2022, Cardinal joined McKesson and AmerisourceBergen in approving a $21 billion national settlement resolving claims from thousands of communities, with Cardinal's portion amounting to $6 billion payable over 18 years to fund abatement efforts like treatment and prevention, effective April 2022; the agreement included injunctive relief mandating enhanced monitoring but no admission of wrongdoing.[65] Specific resolutions included a $215 million deal with Cuyahoga and Summit Counties in Ohio in 2019, addressing local over-distribution claims.[66] In August 2024, Baltimore secured a $152.5 million settlement from Cardinal, paid in full that year following court rulings on liability for contributing to the city's crisis.[9] Shareholder derivative litigation also arose, alleging board failures in overseeing opioid distribution risks; this culminated in a $124 million settlement in 2022, covered by directors' and officers' insurance, without admitting fault, tied to claims of reckless practices exacerbating the epidemic.[39] Post-settlement, Cardinal has reported suspending or terminating hundreds of customer accounts for diversion risks and invested in advanced analytics for order monitoring.[31]Financial Reporting Issues and Investigations
In September 2004, Cardinal Health announced it would restate its financial results for fiscal years 2001, 2002, and 2003, as well as the first three quarters of fiscal 2004, due to improper accounting practices in its Pharmaceutical and Medical/Surgical Services segments.[67] The restatement primarily addressed premature revenue recognition from bulk product deliveries to customers without firm orders, misclassification of vendor rebates as reductions in cost of goods sold rather than separate expenses, and other inventory and rebate accounting errors, resulting in an expected reduction of operating revenue by approximately $1.2 billion and net earnings adjustments including a $12.4 million decrease for fiscal 2004.[68] This disclosure delayed the company's fiscal fourth-quarter earnings report and stemmed from an internal review prompted by SEC inquiries into its accounting practices.[69] The restatement triggered a formal SEC investigation into Cardinal Health's revenue recognition and financial reporting from fiscal year 2001 through the first quarter of fiscal 2005. In July 2007, the SEC charged the company with engaging in a fraudulent scheme to overstate operating revenue and meet Wall Street earnings estimates through methods such as shipping products to customers prior to confirmed orders to inflate sales figures, improperly accelerating vendor rebate recognition, and reclassifying litigation settlement proceeds.[70] Cardinal Health agreed to settle the charges without admitting or denying wrongdoing, paying a $35 million civil penalty and committing to retain an independent consultant to evaluate and enhance its accounting policies, procedures, and financial controls.[71] The settlement resolved allegations that these practices had materially misrepresented the company's financial performance in press releases and SEC filings.[72] Related enforcement actions targeted individual executives. In May 2009, the SEC filed civil suits against three former finance executives—Richard J. Miller (former CFO), Gary S. Jensen (former VP of finance), and Michael E. Beaulieu (former VP of finance)—alleging they facilitated the improper accounting by approving or directing the revenue-inflating shipments and rebate manipulations to achieve earnings targets.[73] The executives were accused of violating antifraud provisions and aiding and abetting the company's reporting deficiencies, though outcomes varied with settlements or judgments in subsequent proceedings.[73] Shareholder litigation ensued, culminating in class-action settlements. A securities fraud class action against Cardinal Health and its officers, arising from the restated earnings and alleged misstatements, was approved for $600 million in 2009, compensating investors for stock price declines following the 2004 disclosures.[74] These events highlighted deficiencies in internal controls over financial reporting, leading to enhanced compliance measures, though no further major U.S. financial restatements have been reported since. In a separate 2020 matter, the SEC imposed an $8.3 million penalty for books-and-records violations tied to inadequate internal controls at a former Chinese subsidiary, involving unreconciled marketing accounts that obscured potential improper payments, but this did not impact consolidated financial statements.[75]Other Regulatory Actions and Compliance Matters
In April 2024, the U.S. Food and Drug Administration (FDA) issued a warning letter to Cardinal Health citing violations of the Federal Food, Drug, and Cosmetic Act for marketing unapproved Monoject syringes as medical devices, along with failures in quality system regulations, including inadequate procedures for purchased components and complaint handling.[76] The letter highlighted risks such as potential syringe incompatibilities leading to medication delivery failures or air embolism, stemming from changes in manufacturing processes after a 2022 ownership transition.[76] [77] Cardinal Health initiated multiple voluntary recalls of Monoject sterile syringes between 2021 and 2024 due to compatibility issues. In August 2021, the company recalled approximately 267 million prefilled saline syringes manufactured from July 2019 to June 2021 over concerns of potential leaks or particulate contamination.[78] In November 2023, the FDA advised against using these syringes with syringe pumps, patient-controlled analgesia pumps, or enteral feeding systems due to risks of malfunction, such as incomplete medication delivery or misconnections.[79] This led to expanded recalls in March and February 2024 for Luer-Lock and enteral syringes across various sizes, classified as Class I (highest risk) by the FDA for potential serious adverse health consequences, including infections or dosing errors.[80] [81] In February 2020, the U.S. Securities and Exchange Commission (SEC) settled enforcement proceedings against Cardinal Health for violations of the Foreign Corrupt Practices Act (FCPA) by its Chinese subsidiary, which maintained off-books marketing accounts to make improper payments totaling over $2.5 million to government-employed healthcare professionals from 2010 to 2013 to influence purchases of the company's radiology products.[82] The settlement required Cardinal Health to pay disgorgement, prejudgment interest, and civil penalties amounting to $8.85 million, with the SEC noting deficiencies in internal accounting controls and anti-corruption compliance programs at the time.[82] Cardinal Health neither admitted nor denied the findings but enhanced its global compliance measures in response.[83]Financial Performance
Revenue Trends and Key Metrics
Cardinal Health's revenue has demonstrated substantial long-term expansion, rising from $93.92 billion in fiscal year 2014 to a peak of $226.8 billion in fiscal year 2024, primarily fueled by growth in pharmaceutical distribution volumes and specialty products.[24][84] This trajectory reflects the company's scale in U.S. drug wholesaling, where it handles generic and branded pharmaceuticals, amid increasing healthcare expenditures and supply chain dependencies.[85] In fiscal year 2025, ending June 30, 2025, total revenue fell to $222.6 billion, marking a 2% decline from the prior year, largely due to the non-renewal of a significant distribution agreement with OptumRx.[17] Excluding the OptumRx impact, revenue grew 18% year-over-year, indicating underlying operational strength in core distribution activities.[7] The Pharmaceutical and Specialty Solutions segment, accounting for approximately 92% of total revenue at $205 billion, drove the majority of this activity, while the Global Medical Products and Distribution segment contributed $13.1 billion, up modestly from prior periods through volume gains in medical supplies.[20][17] Key profitability metrics for fiscal year 2025 include gross profit of $8.17 billion, yielding a gross margin of 3.7%, consistent with the low-margin nature of wholesale distribution influenced by generic drug pricing volatility and reimbursement dynamics.[86] Operating expenses rose to $5.85 billion, reflecting investments in supply chain resilience, while net income stood at approximately $1.56 billion, supporting a net profit margin of 0.7%.[86][87] Return on assets measured 3.16%, underscoring efficient asset utilization in a capital-intensive sector.[87]| Fiscal Year | Total Revenue ($B) | YoY Change (%) | Pharmaceutical Segment ($B) | Medical Segment ($B) |
|---|---|---|---|---|
| 2021 | 162.4 | +12.6 | ~150 | ~12 |
| 2022 | 181.4 | +11.6 | ~167 | ~14 |
| 2023 | 205.0 | +13.1 | ~189 | ~16 |
| 2024 | 226.8 | +10.6 | ~211 | ~16 |
| 2025 | 222.6 | -1.9 | 205 | 13.1 |
Acquisitions, Divestitures, and Economic Impacts
Cardinal Health has strategically pursued acquisitions to expand its footprint in pharmaceutical distribution, specialty care platforms, and medical solutions, often targeting high-margin areas like oncology, urology, and at-home care. For instance, in March 2024, the company acquired Specialty Networks for $1.2 billion, enhancing its capabilities in multi-specialty group purchasing and analytics across therapeutic areas such as rheumatology and gastroenterology. This deal integrated platforms like PPS Analytics, contributing to segment profit growth in the Pharmaceutical and Specialty Solutions division. More recently, in August 2025, Cardinal Health agreed to acquire Solaris Health, the largest urology management services organization in the U.S., for approximately $1.9 billion in cash plus rollover equity, positioning the company to own 75% of the entity and bolstering its urology-focused offerings within The Specialty Alliance.[89] In November 2024, it announced two further deals totaling $3.9 billion: the acquisitions of GI Alliance, a gastroenterology platform, and Advanced Diabetes Supply Group, expected to close in early 2025 and accretive to revenue and segment profit in specialty areas.[90] Earlier notable purchases include Harvard Drug Group in 2015 for $1.115 billion, which strengthened generic pharmaceutical sourcing and distribution networks.[91] In contrast, divestitures have focused on shedding underperforming or non-core medical device assets to streamline operations and reduce exposure to lower-margin segments. The most significant was the 2009 spin-off of its Clinical and Medical Products businesses into CareFusion Corporation, completed on September 1, 2009, via a pro-rata distribution of 81% of shares to shareholders.[92] This separation enabled Cardinal Health to concentrate on its core pharmaceutical distribution, yielding enhanced management focus and strategic clarity, though it involved workforce reductions of about 1,300 jobs and anticipated cost savings of $110 million to $130 million over two years.[93] Another key divestiture occurred in August 2021, when Cardinal Health sold its Cordis cardiology and endovascular business—acquired from Johnson & Johnson in 2017 for around $2 billion—to Hellman & Friedman for approximately $1 billion.[94][95] The sale, at a net loss, negatively affected reported revenues and profits in subsequent fiscal years, as noted in financial disclosures referencing adverse divestiture impacts.[96] These transactions have had mixed but generally positive long-term economic effects, with acquisitions driving revenue diversification and profit margins in high-growth specialties, offsetting declines in traditional distribution. For fiscal year 2025, net acquisitions/divestitures reflected a $10.175 billion outflow, correlating with an 18% underlying revenue increase excluding contract and divestiture effects, reaching $222.6 billion overall.[97] Recent deals, including Specialty Networks and anticipated 2025 closures, have boosted segment profits by 11% to $535 million in key quarters, fueled by management services organizations and specialty products, while divestitures like Cordis pruned costs but incurred short-term hits.[98] Overall, such moves align with Cardinal Health's capital deployment for accretive growth, supporting raised fiscal 2026 guidance amid volatile generics pricing.[99]| Major Transaction | Date | Value | Impact |
|---|---|---|---|
| CareFusion Spin-off (Divestiture) | Sep 2009 | N/A (Share distribution) | Sharpened focus on pharma; $110-130M savings via efficiencies[100] |
| Harvard Drug Group (Acquisition) | Jun 2015 | $1.115B | Enhanced generic sourcing; integrated into distribution for cost efficiencies[91] |
| Cordis Sale (Divestiture) | Aug 2021 | ~$1B | Reduced device exposure; adverse revenue hit in FY22-23[94] |
| Specialty Networks (Acquisition) | Mar 2024 | $1.2B | Added analytics platforms; lifted specialty segment profit |
| Solaris Health (Acquisition) | Aug 2025 (announced) | $1.9B | Urology expansion; expected revenue accretion via MSO[89] |