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Corydalis

Corydalis is a genus of approximately 540 species of annual, biennial, and perennial herbaceous plants in the family Papaveraceae, primarily distributed across the temperate regions of the Northern Hemisphere, with the highest diversity in southwest China and the Himalayas.^[1] These plants typically feature taproots, tubers, or rhizomes; erect to prostrate stems; and basal or cauline leaves that are often compound and bipinnately dissected.^[2] Their flowers are bilaterally symmetric, arranged in bracteate racemes, with four petals—two inner ones forming a crest and one outer petal bearing a prominent spur—evoking the head of a crested lark (korydallis in Greek), the source of the genus name.^[3] Fruits are dehiscent capsules containing reniform to subglobose seeds often equipped with an elaiosome for ant dispersal, and the chromosome number is x = 8.^[2] The genus, first described by Augustin Pyramus de Candolle in 1805 and conserved under the International Code of Nomenclature, represents the largest in Papaveraceae, with species adapted to diverse habitats from woodlands and meadows to alpine slopes and rocky outcrops.^[1] While about 10 species occur in North America—such as the yellow-flowered C. aurea and pink C. sempervirens—the majority are Eurasian, extending into parts of Africa, with ongoing taxonomic revisions due to morphological complexity and recent phylogenetic studies.^[2]^[4] Several Corydalis species hold significance in traditional medicine, particularly in Chinese herbal practices, where tubers of species like C. yanhusuo (Yan Hu Suo) are used for analgesia, treating conditions such as headaches, abdominal pain, and menstrual cramps due to bioactive alkaloids like tetrahydropalmatine.^[5] Modern research supports these uses, identifying anti-inflammatory, anti-addictive, and neuroprotective properties in extracts, though clinical applications remain limited by variability in compound profiles.^[6] Ornamentally, species such as C. lutea and C. flexuosa are valued in gardens for their delicate, long-blooming flowers in shades of yellow, pink, blue, and purple, thriving in shaded, well-drained soils.^[3]

Description

Morphology

Corydalis species are primarily herbaceous perennials, though some are annuals, characterized by underground storage organs that vary from tubers and rhizomes to taproots, rootstocks, or fibrous roots depending on the subgenus and section. These organs often serve as nutrient reserves and can be round or elongated, with tubers prominent in many Asian taxa for overwintering survival. For instance, the ancestral condition is believed to be a taproot, but derived forms include fleshy tubers in subgenus Corydalis s.l. and enlarged storage roots in sections like Trachycarpae.^[7]^[8] Stems are typically erect or ascending, frequently weak and sprawling, reaching heights of 5-40 cm, and are often glaucous in appearance. They bear compound leaves that are ternately or pinnately (often bipinnately) divided into lobed or dissected segments, with basal leaves larger and more elaborate than the smaller cauline leaves along the stem. Leaf coloration ranges from green to glaucous, aiding in camouflage in alpine or forest understories. These parts, particularly the tubers and rhizomes, contain isoquinoline alkaloids such as protopine, which contribute to the plant's pharmacological properties.^[9]^[10]^[7] Flowers are arranged in racemose inflorescences, typically terminal or axillary, and exhibit zygomorphic symmetry with a distinctive spurred petal that serves as a key taxonomic trait. The corolla comprises four unequal petals, with the upper one bearing a nectar spur that varies in length and shape—often 1-2 cm and cylindrical or saccate in many Asian species—while colors span yellow (ancestral), purple, white, pink, and blue. Sepals are minute and sometimes petaloid, and the flowers are asymmetrical with crested inner petals. Fruits develop as dehiscent capsules, linear to oblong in shape, that split to release numerous small, smooth seeds equipped with elaiosomes, facilitating ant-mediated dispersal—a trait present across the genus.^[10]^[8]^[9] Morphological variations are pronounced across the four recognized subgenera, influencing overall habit from upright perennials in subgenus Corydalis to more creeping or decumbent forms in subgenera like Cremnocapnos and Sophorocapnos, driven by differences in underground structures and lifespan. For example, subgenus Bipapillatae features distinct fruit and spur morphologies, while section-level diversity affects leaf dissection and inflorescence density. These traits underscore the genus's adaptability in temperate habitats.^[8]^[7]

Reproduction

Corydalis species primarily reproduce sexually through hermaphroditic flowers that are pollinated by bees and other insects, such as long-tongued bumblebees and skipper butterflies.^[11]^[12] Some species exhibit self-incompatibility, preventing self-fertilization and promoting outcrossing, while others are self-compatible.^[13] Flowering occurs from spring to summer, with many temperate species blooming in early spring, such as March to April, depending on regional climate.^[3]^[14] Following pollination, capsules develop and produce a high yield of seeds, typically 20-25 per capsule in species like Corydalis sempervirens.^[11] Seed dispersal is facilitated by myrmecochory, where elaiosomes on the seeds attract ants that carry them to nests, achieving dispersal distances of up to 2-3 meters on average.^[15]^[16] In addition to sexual reproduction, some species propagate asexually through vegetative spread via tubers or rhizomes, forming clonal colonies. Germination in many Corydalis species requires cold stratification to break dormancy, typically at temperatures around 1-5°C for several weeks, followed by optimal growth at 15-20°C.^[17] The life cycle varies across species but is generally that of annuals, biennials, or short-lived perennials, with plants often completing reproduction in one or two seasons before senescence.^[11]^[18]

Distribution and Ecology

Geographic Range

Corydalis species are native to the temperate regions of the Northern Hemisphere, with the majority occurring in Asia, Europe, and North America. The genus exhibits its highest diversity in eastern Asia, particularly in China, where approximately 357 species are recorded, of which 262 are endemic. This concentration extends to the Himalayas and adjacent areas, including parts of Japan, underscoring the Sino-Himalayan region as a primary center of speciation. In Europe, approximately 35 species are present, primarily in temperate and mountainous zones, while North America hosts about 10 native species, often showing disjunct distributions in the western regions such as the Rocky Mountains and Pacific Northwest.^[19]^[20]^[2] Introduced populations have expanded the genus's range beyond its native areas, with species like Corydalis solida becoming naturalized in parts of North America, including the northeastern United States and Canada, as well as in Australia, where it persists as an ornamental escape. These introductions, often facilitated by horticultural trade, have led to self-sustaining populations in temperate woodlands and disturbed sites. Historical migration patterns, inferred from phylogenetic and fossil evidence, trace back to the Miocene epoch (approximately 23 to 5 million years ago), when ancestral lineages diversified amid tectonic uplifts and climatic shifts, contributing to vicariance events that isolated populations across continents. Ongoing discoveries, such as the 2024 description of C. sunhangii in Xizang, continue to reveal new species in the region. Additionally, warming climates are projected to shift suitable ranges for some populations.^[21]^[22]^[23]^[24] Endemism hotspots within China, such as the provinces of Sichuan and Yunnan, harbor numerous alpine-adapted species, many of which are endemic to these mountainous areas due to topographic complexity and climatic heterogeneity. Conservation challenges are acute in these regions, where habitat loss from deforestation, agricultural expansion, and urbanization threatens several species; for instance, Corydalis saxicola, a lithophytic herb endemic to Guangxi and nearby provinces, is listed as endangered primarily due to overexploitation and associated habitat degradation. These patterns highlight the genus's vulnerability in biodiversity hotspots, emphasizing the need for targeted protection amid ongoing environmental pressures.^[25]^[26]^[27]

Habitat and Growth

Corydalis species primarily inhabit woodland understories, rocky slopes, and alpine meadows across temperate and subtropical regions, where they thrive in shaded or semi-shaded environments with partial sunlight filtering through canopies or rock outcrops.^[19] These plants are adapted to a range of ecological niches, including forest floors, alpine scree, riversides, shrublands, grasslands, and cliffsides up to elevations of 5500 m, often in areas with low competition from taller vegetation.^[28] Many species exhibit shade tolerance, enabling them to form low-growing mats or cushions in moist, humus-rich forest understories or on well-drained rocky substrates.^[29] Soil preferences for Corydalis include neutral to slightly acidic pH levels (5.5–7.0) in humus-rich, loamy substrates that retain moisture without becoming waterlogged, as the genus shows intolerance to heavy, saturated conditions that can lead to root rot.^[30] Well-drained soils, often sandy or gravelly in rocky habitats, support their growth by preventing excess moisture accumulation, while organic matter enhances nutrient availability in these often nutrient-poor environments.^[11] Climatically, Corydalis spans cool temperate zones to subtropical areas, with many species functioning as geophytes that emerge in spring following winter dormancy, leveraging early-season warmth and moisture before canopy closure in deciduous forests.^[31] Adaptations include tolerance to cold winters and high-altitude conditions in alpine settings, though some populations in eastern Asia face shifts in suitable ranges due to warming climates.^[24] Growth phenology varies: spring ephemerals like Corydalis solida produce fleeting leaves and flowers before entering summer dormancy to avoid heat stress, while others maintain semi-evergreen foliage in milder, shaded microhabitats.^[29] Ecologically, Corydalis contributes as ground cover in forest ecosystems, stabilizing soil on slopes and providing early-season nectar for pollinators such as bees and hoverflies, thereby supporting biodiversity in understory communities.^[32] Some species interact with soil fungi for enhanced nutrient uptake, though associations are less pronounced than in other families, aiding survival in low-nitrogen alpine or rocky soils.^[33] In response to disturbance, certain Corydalis species act as pioneers in early-successional sites like disturbed stream banks or degraded forests, rapidly colonizing open ground with wind-dispersed seeds, yet many prove sensitive to large-scale deforestation, which disrupts shade and moisture regimes essential for their persistence.^[10]^[11]

Taxonomy

Classification History

Corydalis belongs to the family Papaveraceae, specifically the subfamily Fumarioideae, and is closely related to the genus Fumaria, sharing morphological and molecular traits within this group. The genus name derives from the Greek korydalis, meaning "crested lark," alluding to the spurred flowers that resemble the bird's crest.^[2] The genus was formally established in 1805 by Augustin Pyramus de Candolle, who conserved the name while incorporating species previously classified under Fumaria by Carl Linnaeus in his 1753 Species Plantarum, where Linnaean taxa like Fumaria bulbosa var. solida were later reassigned to Corydalis.^[2]^[34] Early taxonomic treatments emphasized morphological features such as flower spurs and fruit structure, but the genus's hyper-diversity—encompassing around 530 species—posed significant challenges, leading to fragmented classifications. In the 1990s, Magnus Lidén advanced revisions using molecular data, including chloroplast rps16 intron sequences, to delineate three subgenera (Corydalis, Pistolochia, and Cremnocapnos) based on phylogenetic relationships and morphology.^[35]^[36] These efforts highlighted Corydalis's monophyly within Fumarioideae and incorporated DNA evidence to refine sectional boundaries, with approximately 40 sections proposed by Wu in 1996 on morphological and geographic grounds.^[36] Subsequent phylogenomic studies have further refined the classification, recognizing about 10 major sectional groups initially, evolving to 39 sections across four subgenera in a 2023 update, integrating plastid and nuclear genes with morphological data; for instance, section Corydalis encompasses Old World species characterized by specific spur and leaf traits. Phylogenetic analyses confirm the genus as monophyletic, with basal clades centered in Asia, particularly the Himalaya-Hengduan Mountains, reflecting an Eocene origin and subsequent radiations driven by tectonic uplift.^[37] Hybridization events have been documented in certain lineages, contributing to morphological variability.^[38] The high speciation rate in Corydalis, especially in alpine habitats, has resulted in numerous cryptic species that are morphologically indistinguishable, complicating delimitation and necessitating ongoing revisions through sequencing of nuclear ITS regions and chloroplast matK genes for barcoding and phylogeny.^[36] These molecular tools have improved species discrimination to about 70% when combined, aiding in resolving taxonomic ambiguities in this hyper-diverse genus.^[39]

Species Diversity

The genus Corydalis encompasses approximately 545 accepted species of herbaceous plants, with ongoing taxonomic additions driven by discoveries in Asia, particularly China, where new species continue to be described from remote montane areas.^[1] This hyperdiverse genus, the largest in the Papaveraceae family, reflects a complex evolutionary history marked by morphological variability and adaptive radiation.^[40]^[37] Notable species highlight the genus's ecological and human significance. C. yanhusuo, native to China, is renowned for its analgesic alkaloids used in traditional medicine, while C. solida, distributed from Europe to Central Asia, is widely cultivated for its attractive spring blooms in ornamental gardens. In contrast, C. incisa, originating from East Asia, poses invasive risks in North American woodlands, where it spreads rapidly in shaded understories and competes with native flora. Regional endemism is pronounced, with over 300 species recorded in China, including more than 200 endemics concentrated in southwestern provinces like Yunnan and Sichuan.^[5]^[41]^[42]^[20] Infrageneric classification recognizes four subgenera and 39 sections, many of which are monophyletic based on recent phylogenomic analyses. Several species previously assigned to Corydalis have been reclassified into related genera, such as Capnoides; for instance, the North American C. sempervirens is now Capnoides sempervirens, reflecting distinctions in floral symmetry and flavonoid profiles. Post-2000 taxonomic revisions, including synonym resolutions in floras and molecular studies, have stabilized much of this nomenclature, reducing redundancy from earlier descriptions.^[40]^[43] Diversity peaks in montane Asia, especially the Qinghai-Tibet Plateau and Himalayas, where habitat heterogeneity fosters speciation in alpine meadows and forest edges. Life forms are predominantly perennial (about 90%), with tuberous or rhizomatous roots enabling persistence in seasonal environments, while a smaller proportion consists of annuals or biennials suited to disturbed sites. Conservation concerns affect around 20 species, several of which—such as C. cashmeriana and C. crispa—are IUCN-listed as endangered due to overcollection for medicinal trade and habitat degradation in high-altitude regions.^[37]^[44]^[45]

Phytochemistry

Alkaloids

The genus Corydalis is renowned for its rich content of isoquinoline alkaloids, which constitute the primary phytochemical class defining its chemical profile. These alkaloids, predominantly derived from benzylisoquinoline precursors, encompass major subclasses such as protoberberines (e.g., protopine, allocryptopine, palmatine), tetrahydroprotoberberines (e.g., tetrahydropalmatine, THP), aporphines (e.g., bulbocapnine, glaucine), and protopines, along with quaternary isoquinolines and phthalideisoquinolines.^[46]^[47] Other notable types include benzophenanthridines and simple isoquinolines, contributing to the structural complexity observed across the genus.^[46] Over 380 distinct alkaloids have been identified in Corydalis species to date, with protoberberine and aporphine types being the most dominant in terms of abundance and diversity.^[46] Structural variations arise from differences in ring saturation, oxidation states, methoxylation patterns, and stereochemistry, often resulting in enantiomeric pairs or ring-rearranged forms like seco-isoquinolines.^[46]^[48] These modifications enhance the alkaloids' chemical stability and biological interactions, with more than 60 benzylisoquinoline alkaloids (BIAs) reported in a single species like C. yanhusuo.^[47] The biosynthesis of these isoquinoline alkaloids in Corydalis begins with the amino acid tyrosine, which is decarboxylated to dopamine and condensed with 4-hydroxyphenylacetaldehyde to form (S)-norcoclaurine, catalyzed by norcoclaurine synthase (NCS). Subsequent N-methylation and 3'-hydroxylation via enzymes like N-methylcoclaurine 3'-hydroxylase (NMCH, a CYP80G family oxidase) lead to the key intermediate (S)-reticuline. From reticuline, the pathway branches: CYP80B1-like oxidases facilitate the formation of (S)-scoulerine, a precursor to protoberberines, while O-methyltransferases (e.g., 6-OMT, CNMT) and additional cytochrome P450s (e.g., CYP82 family) drive diversification into aporphines and other subclasses.^[47]^[49]^[50] This reticuline-centered route is highly conserved but shows tissue-specific expression, with tuber-enriched transcripts for BIA-related genes in C. yanhusuo.^[47] Species-specific alkaloid profiles vary significantly, reflecting adaptations to local environments; for instance, C. yanhusuo tubers accumulate high levels of THP (up to approximately 1% dry weight) alongside dehydrocorydaline and protopine, comprising 0.5–1% total alkaloids overall.^[5] In contrast, aporphine alkaloids like bulbocapnine predominate in the tubers of species such as C. bulbosa and C. yanhusuo, often serving as major constituents.^[51]^[52] Other species, like C. hendersonii, feature unique protoberberines and spirobenzylisoquinolines.^[53] Alkaloids are typically extracted from rhizomes and tubers using solvent-based methods, such as methanol or ethanol Soxhlet extraction, followed by acid-base partitioning to isolate basic fractions. Quantification relies on high-performance liquid chromatography-mass spectrometry (HPLC-MS), enabling simultaneous detection of multiple compounds with high sensitivity and resolution for structural confirmation via electrospray ionization.^[54]^[55] These techniques have revealed variability in alkaloid yields influenced by plant age, habitat, and processing.^[55] Evolutionarily, these alkaloids function as chemical defenses against herbivores and pathogens, with profiles varying by habitat to optimize deterrence—e.g., higher concentrations in exposed tubers of alpine species. This defensive role is supported by the alkaloids' toxicity to insects and microbes, promoting plant survival in diverse ecosystems.^[56]^[47]

Other Compounds

Corydalis species contain various non-alkaloid phytochemicals, including flavonoids, terpenoids, phenolics, and volatile oils, which contribute to the plant's overall chemical profile and ecological adaptations.^[57] Flavonoids, primarily quercetin derivatives and kaempferol glycosides, are prominent in Corydalis, particularly in species like C. bungeana, where they are isolated from aerial parts including leaves.^[58] These compounds accumulate in leaves, potentially aiding in UV protection through absorption of harmful radiation, a common function in herbaceous plants.^[59] Quantitative analysis shows flavonoid content varying by species and season, reaching up to 0.32% dry weight in aerial parts of C. solida, with quercetin detected at 3247 µg/g.^[60] Such variations highlight environmental influences on biosynthesis, with higher levels often observed during vegetative growth phases.^[61] Terpenoids in Corydalis are limited but include sesquiterpenes, such as a novel nor-sesquiterpene glycoside identified in the whole plant of C. edulis.^[62] These are concentrated in roots and exhibit potential anti-inflammatory properties typical of sesquiterpenes, though specific bioactivities in Corydalis require further investigation.^[63] Phenolic compounds, notably phenolic acids like ferulic acid and isoferulic acid, occur in Corydalis species such as C. bungeana, contributing to antioxidant capacity.^[64] Hydroxycinnamic acids, including ferulic acid derivatives, are among the non-alkaloid constituents in aerial and underground parts, supporting oxidative stress resistance.^[57] Volatile oils are present in small amounts, primarily in flowers, comprising monoterpenes that dominate scent profiles in species like C. cava and C. cirrhosa (93–99% of volatiles).^[65] These include compounds such as (E)-β-ocimene, facilitating pollinator attraction through floral emission.^[66] Analytical methods like gas chromatography-mass spectrometry (GC-MS) are commonly employed to characterize these volatiles, enabling identification of monoterpenes and seasonal fluctuations in composition.^[67]

Uses

Medicinal Applications

In traditional Chinese medicine, Corydalis yanhusuo, known as Yan Hu Suo, has been used for centuries to relieve pain, particularly that associated with blood stasis, as well as for treating menstrual disorders and promoting qi circulation.^[68]^[69] The typical dosage involves 3-10 grams of the dried rhizome decoction per day, often administered in formulas for conditions like neuralgia and abdominal pain.^[70] Modern pharmacological research highlights tetrahydropalmatine (THP), a key alkaloid in C. yanhusuo, which acts as a dopamine D2 receptor antagonist to provide analgesia without significant tolerance development.^[71] THP's potential analgesic effects have been demonstrated in preclinical models of neuropathic and inflammatory pain.^[68]^[72] Beyond analgesia, Corydalis species exhibit anti-inflammatory effects suitable for arthritis management, with extracts reducing inflammatory markers in preclinical models.^[73] Cardiovascular benefits include vasodilation mediated by THP, which relaxes blood vessels and may support circulatory health.^[74] Additionally, extracts from C. saxicola show hepatoprotective properties, protecting against liver damage in hepatitis models through antioxidant mechanisms.^[75]^[76] Commercial formulations of C. yanhusuo extracts are often standardized to 10-20% total alkaloids (with THP as the main component), typically dosed at 100-200 mg multiple times daily; however, significant variability in alkaloid content has been reported in products as of 2025.^[77]^[78] Patents since 2010 have explored Corydalis-based compositions for migraine treatment, combining it with other herbs to enhance pain relief and reduce recurrence.^[79] Despite promising preclinical data, research gaps persist, including a scarcity of large-scale randomized controlled trials (RCTs) to confirm broader therapeutic applications as of 2025.^[80] In China, Corydalis is approved as an analgesic in traditional formulations, while in the US, it is marketed as a dietary supplement with FDA warnings about potential bleeding risks and lack of pre-market approval for therapeutic claims. Additionally, as of 2025, research has identified potential risks of idiosyncratic liver injury associated with its use, emphasizing the need for medical supervision.^[81]^[82]^[83]^[84]

Ornamental Value

Corydalis species are prized in ornamental horticulture for their delicate, tubular flowers and fern-like foliage, which add subtle color and texture to shaded garden settings. Popular cultivars include Corydalis flexuosa hybrids, such as 'Pere David', known for their vibrant blue blooms emerging in spring, and C. lutea, an evergreen species with bright yellow flowers that provide year-round interest through its lacy, blue-green leaves. These plants are generally hardy in USDA zones 5-8, thriving in cool, temperate climates where they can naturalize without excessive heat stress.^[85]^[3]^[86] In garden design, Corydalis excels in shade borders, rock gardens, and woodland plantings, where its low-growing habit (typically 6-12 inches tall) creates a soft understory layer. It pairs well with ferns and hostas, enhancing the naturalistic feel of moist, humus-rich sites that mimic their native woodland habitats. The aesthetic appeal lies in the springtime display of nodding flowers in shades ranging from white and pink to purple and blue, complemented by textured foliage that remains attractive even after blooming.^[87]^[30]^[88] Breeding efforts since the 1990s have focused on extending bloom duration and improving vigor, with notable UK hybrids like C. 'Craigton Blue'—a cross between C. flexuosa and C. omeiana—offering prolonged flowering and greater tolerance to varying conditions compared to wild forms. These developments arose from chance seedlings and targeted selections in British gardens, resulting in more reliable performers for temperate landscapes. Select cultivars, such as certain C. flexuosa varieties, have earned the Royal Horticultural Society's Award of Garden Merit (AGM) for their outstanding garden performance and availability.^[89]^[90]^[91] Market availability is strong through nursery propagation, with plugs and divisions widely offered by specialty perennial growers for easy integration into home gardens. However, Corydalis can be short-lived in hot climates, often going dormant after spring bloom due to heat intolerance, though mulching with organic matter helps retain soil moisture and moderate temperatures to extend plant longevity.^[29]^[86]^[30]

Toxicity and Safety

Effects on Humans and Animals

Corydalis species contain isoquinoline alkaloids that can exert toxic effects on humans primarily through gastrointestinal and neurological symptoms at high doses, with rare instances of hepatotoxicity associated with chronic exposure. Common adverse reactions include nausea, vertigo, fatigue, and dizziness, often reported in individuals consuming alkaloid-rich extracts or supplements. Hypotension may occur with elevated doses of tetrahydropalmatine (THP), a key alkaloid exceeding 150 mg daily, potentially exacerbating cardiovascular risks. Hepatotoxicity, though uncommon, has been documented in case reports involving chronic use of Corydalis-containing sleep aids, manifesting as elevated transaminases, jaundice, dark urine, and vomiting in symptomatic patients, with liver function typically normalizing upon discontinuation. Recent 2025 studies suggest that C. yanhusuo may induce idiosyncratic hepatotoxicity through inflammatory pathways in activated models.^[70]^[92]^[84] In animals, Corydalis alkaloids pose risks particularly to livestock such as sheep and cattle grazing in affected pastures, where species like Corydalis aurea have been implicated in poisoning incidents due to their alkaloid content. Rodent studies indicate moderate acute toxicity, with the median lethal dose (LD50) for total alkaloids from Corydalis rhizomes approximately 473 mg/kg in mice, leading to symptoms including muscle tremors and organ damage. Veterinary reports highlight sporadic cases of intoxication in ruminants, though specific mortality rates remain low outside overgrazed areas.^[93]^[46]^[94] The toxic mechanisms involve alkaloid interactions with neural and muscular systems; for instance, THP modulates GABA_A receptors, contributing to sedative effects that can progress to central nervous system depression at higher exposures. Protopine exhibits smooth muscle relaxant properties, potentially influencing gastrointestinal and cardiovascular function, while overall alkaloid activity may disrupt ion channels and neurotransmitter balance, amplifying sedation and hypotensive responses. No direct evidence links canadine specifically to calcium channel blockade in Corydalis toxicity, though related isoquinoline alkaloids show such effects in broader pharmacological contexts.^[5]^[95] Accidental ingestion cases in humans are rare but include pediatric exposures to Corydalis plants or extracts, potentially resulting in vomiting, nausea, and abdominal discomfort due to the toxic alkaloids. In veterinary settings, pasture-related incidents involve livestock consuming Corydalis aurea, leading to general signs of alkaloid intoxication such as weakness and gastrointestinal upset, though detailed case studies are limited.^[96]^[93] Toxicity is influenced by alkaloid concentrations, which are highest in roots and tubers (typically 0.5–1% dry weight) compared to aerial parts, with levels varying seasonally—peaking in early autumn in underground organs due to biosynthetic accumulation. No specific antidote exists for Corydalis poisoning; management relies on supportive care, including gastrointestinal decontamination with activated charcoal to adsorb alkaloids and prevent absorption, alongside monitoring for hypotension and sedation.^[5]^[97]^[98]

Management in Cultivation

Corydalis species thrive in partial shade to full shade conditions, mimicking their native woodland habitats, where full sun exposure can lead to leaf scorching and reduced vigor. Optimal soil is moist yet well-drained, humus-rich, and organically enriched, with a preferred pH range of 6.0 to 7.0 to support root development and prevent nutrient lockout. Planting sites should ensure consistent moisture without waterlogging, often achieved by incorporating compost or leaf mold into the soil prior to planting.^[30]^[99]^[100] Propagation of Corydalis can be accomplished through division of tubers or rhizomes in early fall, allowing plants to establish before winter dormancy, or via seed sowing. For seeds, fresh collection in late spring or summer is ideal, followed by a warm stratification period of about two months at room temperature, then cold stratification for 4-6 weeks at around 4°C to break dormancy and improve germination rates, which typically reach 70-80% under controlled conditions. Divisions should be replanted immediately at 15-20 cm spacing in prepared beds, while stratified seeds are sown shallowly in pots and kept moist until seedlings emerge.^[101]^[102]^[103] Ongoing maintenance involves mulching with organic materials like bark or compost in spring to retain soil moisture and suppress weeds, particularly beneficial during dry spells. Fertilization should be minimal, using a low-nitrogen balanced formula such as 5-10-10 NPK applied once in early spring to avoid excessive foliage at the expense of blooms, as Corydalis prefers lean conditions. Regular monitoring for moisture levels is essential, with supplemental watering during prolonged dry periods to prevent tuber desiccation.^[104]^[29]^[105] Common pests include slugs, which can damage tender foliage, best controlled through physical barriers like copper tape or diatomaceous earth around plants, while fungal root rot is mitigated by ensuring proper spacing of 15-20 cm between individuals to promote air circulation and quick drying after rain. Disease prevention also involves avoiding overhead irrigation to reduce humidity on leaves. Integrated approaches, such as hand-removal of slugs and soil amendments for drainage, effectively manage these issues without heavy chemical reliance.^[106]^[107] Given the presence of isoquinoline alkaloids in Corydalis that can cause gastrointestinal distress if ingested, gardeners should wear gloves during planting, division, and pruning to avoid skin irritation, and position plants away from areas accessible to pets or livestock. Plant waste should be discarded securely in compost piles inaccessible to animals or incinerated to prevent accidental exposure.^[108]^[109] To promote sustainability, Corydalis should be sourced from ethical nurseries specializing in propagated stock rather than wild-collected specimens, as certain species face overharvesting pressures for medicinal uses, helping preserve natural populations. Cultivation in gardens reduces demand on wild resources and supports biodiversity through controlled propagation.^[110]^[111]

References

[1]
Corydalis - FNA - Flora of North America
Nov 5, 2020 · Distribution. Temperate North America, Eurasia, and Africa ... Monograph of the North American species of Corydalis. Ann. Missouri ...
[2]
Yellow Corydalis, Corydalis lutea - Wisconsin Horticulture
The genus has about 300 species and is named for the Greek korydalis, crested lark, referring to the flower's resemblance to the lark's head.
[3]
Corydalis DC. | Plants of the World Online | Kew Science
Native to: Afghanistan, Alabama, Alaska, Albania, Alberta, Algeria, Altay, Amur, Arizona, Arkansas, Assam, Austria, Baltic States, Bangladesh, Belarus, ...
[4]
Taxonomic identity of Corydalislidenii (Papaveraceae) - PMC - NIH
Feb 17, 2022 · The genus Corydalis DC., the largest genus of Papaveraceae, contains about 465 species mainly distributed in the northern temperate zone with ...
[5]
The Analgesic Properties of Corydalis yanhusuo - PubMed Central
Dec 10, 2021 · Corydalis yanhusuo extract (YHS) has been used for centuries across Asia for pain relief. The extract is made up of more than 160 compounds.
[6]
UCI-led Study Finds Medicinal Plant Extract to Prevent Morphine ...
Oct 12, 2021 · The extract of the plant Corydalis yanhusuo prevents morphine tolerance and dependence while also reversing opiate addiction, according to a recent study.
[7]
https://doi.org/10.3389/fpls.2022.926574
[8]
https://doi.org/10.1111/jipb.13499
[9]
Corydalis - an overview | ScienceDirect Topics
Habitat and Description ... This perennial herb grows in China, Mongolia, Russia, Pakistan, India, and Nepal. The whole plant is glaucous and grows to 50 cm tall.
[10]
[PDF] Corydalis flavula (Raf.) DC. yellow fumewort
Members of the genus Corydalis are herbs with bipinnately dissected leaves and short, bracteate racemes bearing asymmetrical flowers with dilated, keeled outer ...
[11]
Corydalis sempervirens - USDA Forest Service
Pollination and breeding system: Rock harlequin may outcross but has perfect flowers [31,33,34,59,72,99] and is fully self-compatible. The fittest plants in ...
[12]
Differential effects of nectar robbing by the same bumble-bee ...
A system of three sympatric Corydalis species sharing the same nectar-robbing bumble-bee was therefore studied over 3 years in order to investigate the effect ...
[13]
Nectar thieves influence reproductive fitness by altering behaviour of ...
Aug 10, 2025 · ... Corydalis ambigua is a self-incompatible perennial herb, so selfpollen cannot germinate on the stigma of the same flower (also see Ohara & ...
[14]
(PDF) Early Spring Nectar and Pollen and Insect Visitor Behavior in ...
The phenology of Corydalis species showed distinct year-to-year plasticity (e.g., blooming period in March - April or in April - May; duration 18 - 42 days).
[15]
(PDF) The fate of Corydalis cava elaiosomes within an ant colony of ...
Aug 5, 2025 · The diaspores of many plant species are adapted to dispersal by ants (myrmecochory). The ants carry the diaspores into their nests where the ...
[16]
Directed Dispersal: Demographic Analysis of an Ant-Seed Mutualism
This has been called "directed dispersal." We examine the effects of seed dispersal by ants on the demography of two seed cohorts of Corydalis aurea: one ...
[17]
Comparisons of Natural and Cultivated Populations of Corydalis ...
Jul 2, 2020 · In the production of cultivated C. yanhusuo, the tubers are usually planted in October, propagated through asexual reproduction, and harvested ...
[18]
Temperature conditions control embryo growth and seed ...
Aug 7, 2025 · Corydalis cava is a spring flowering woodland tuberous geophyte widely distributed across Europe. Germination phenology, including embryo ...
[19]
http://www.efloras.org/florataxon.aspx?flora_id=2&taxon_id=108085
[20]
Corydalis in Flora of China @ efloras.org
Herbs, annual, biennial, or perennial, soft, juicy, usually glabrous. Leaves usually alternate, pinnately or ternately divided.
[21]
Corydalis - an overview | ScienceDirect Topics
Around 428 species of genus Corydalis are distributed worldwide, 298 of which are in China, and 10 groups and 219 species are endemic in China. Corydalis is ...
[22]
Corydalis solida (spring corydalis) - Go Botany - Native Plant Trust
Facts. Spring corydalis is native to northern Europe and Asia. It is introduced in North America, including New England, where it is known from Connecticut, ...Missing: geographic range
[23]
Repeated Evolution of Storage Root and Invasions of Alpine Biome ...
The storage root has originated independently at least 6 times in Corydalis since the Miocene, and its acquisition could have operated as a key innovation ...Missing: records | Show results with:records
[24]
(PDF) Corydalis in China I: Some new species - ResearchGate
Twenty-nine new species of Corydalis (Fumariaceae) from China, mainly from Tibet, Sichuan and Yunnan, are described. A, Corydalis tsangensis (holotype); B, C.
[25]
[PDF] Endemic Wild Ornamental Plants from Northwestern Yunnan, China
Among the endemic genera, Pedicularis and Rhododendron have particularly high numbers of ornamental wild species, while Aconitum, Gentiana, Corydalis, Silene,.
[26]
Highly variable chloroplast genome from two endangered ...
Mar 19, 2021 · In this study, we sequenced four complete cp genomes of two endangered lithophytes Corydalis saxicola and Corydalis tomentella in Corydalis ...
[27]
Proportion of flowering plants at each age class in Corydalis ...
Females had a higher total effort, which first increased and then decreased with age. The latter may be a response to an increasing reproductive value—an ...
[28]
Corydalis | Portland Nursery
Corydalis is a shady plant with cheerful flowers and foliage, needing well-drained soil, and is native to the Northern Hemisphere, especially China.<|separator|>
[29]
How to Plant and Grow Corydalis - Better Homes & Gardens
Aug 17, 2023 · Corydalis grows best in humus-rich, moist, well-drained soil with a slightly acidic to neutral pH (5.0 to 7.0). Corydalis needs consistent ...Missing: intolerance | Show results with:intolerance
[30]
Bud development in corydalis (Corydalis bracteata) requires low ...
The flowering process involves three major stages: (1) initiation of floral meristem and differentiation of floral parts; (2) slow growth and maturation of the ...
[31]
Prediction Analysis of Integrative Quality Zones for Corydalis ...
Aug 1, 2025 · They found that the plant currently grows best in specific regions of Central and Eastern China. However, as the climate warms, these suitable ...
[32]
Corydalis sempervirens (Pale Corydalis) - Minnesota Wildflowers
Pale Corydalis is a biennial, native plant with pale rose to deep pink flowers with yellow lips, found in rocky, sandy soil, and grows 12 to 40 inches tall.Missing: understories slopes alpine meadows pH mycorrhizal
[33]
Morphology and anatomy of snow roots of Corydalis conorhiza. a ...
These authors found that the endemic snow bed specialist Corydalis conorhiza, a member of the Papaveraceae family, not only develops regular roots in the soil, ...
[34]
Corydalis sunhangii (Papaveraceae): A new species from Xizang ...
Our new species belongs to Corydalis sect. Trachycarpae (Fedde) Fedde, characterized by fasciculate fleshy storage roots, reflexed fruiting pedicels, and ...
[35]
(PDF) DNA barcoding of Corydalis , the most taxonomically ...
PDF | The genus Corydalis is recognized as one of the most taxonomically challenging plant taxa. It is mainly distributed in the Himalaya–Hengduan.
[36]
DNA barcoding of Corydalis, the most taxonomically complicated ...
The genus Corydalis is recognized as one of the most taxonomically challenging plant taxa. It is mainly distributed in the Himalaya–Hengduan Mountains, a global ...
[37]
New Insights Into the Backbone Phylogeny and Character Evolution ...
Aug 4, 2022 · Corydalis DC. is the largest genus within Papaveraceae, containing over 500 species (Catalogue of Life, 2022) divided into ca. 40 sections ( ...
[38]
Phylogeny of Corydalis, ITS and morphology - SpringerLink
The phylogeny of Corydalis was deduced from sequences of the transcribed spacers in the nuclear ribosomal DNA. A unique derivation of zygomorphic flowers ...Missing: Asian hybridization<|separator|>
[39]
DNA barcoding of Corydalis, the most taxonomically complicated ...
Jan 21, 2019 · Overall, Wu (1996) classified Corydalis into two subgenera based on morphological characteristics and geographical distributions. Linden (1997) ...
[40]
https://onlinelibrary.wiley.com/doi/full/10.1111/jipb.13499
[41]
Corydalis solida (L.) Clairv. | Plants of the World Online | Kew Science
The native range of this species is Europe to Central Asia, NW. Africa. It is a tuberous geophyte and grows primarily in the temperate biome.
[42]
Incised Fumewort (Corydalis incisa) (U.S. National Park Service)
May 6, 2024 · The invasive species has purple flowers while the native (C. flavula) have yellow flowers. Corydalis flavula can be found along riverbanks, rock ...
[43]
Capnoides sempervirens - Vascular Plants of North Carolina
This is a unique species, especially as it has been removed from the genus Corydalis to now Capnoides, where it is the only species. It is conspicuously ...
[44]
Assessment of threat status of selected endemic medicinal plants ...
Three of these (Atropa acuminata, Aquilegia nivalis and Corydalis cashmeriana) meet the criteria for Endangered (EN) threat category while the remaining three ...
[45]
(PDF) Ecological status of high altitude medicinal plants and their ...
Oct 6, 2016 · Onosma hookeri, Corydalis crispa and Delphinium glaciale were some of the species ranked as threatened species followed by Halenia elliptica ( ...
[46]
Systematic review of the alkaloid constituents in several important ...
Alkaloids were the most important compounds with diversity structures in Corydalis. Abstract. The genus Corydalis is a botanical source of various ...
[47]
Integration of full-length transcriptomics and targeted metabolomics ...
Jan 10, 2021 · Benzylisoquinoline alkaloids (BIAs) are the main bioactive ingredients in Corydalis yanhusuo. However, few studies have investigated the BIA ...<|control11|><|separator|>
[48]
Yanhusanines A–F, Isoquinoline-Derived Alkaloid Enantiomers from ...
Feb 14, 2020 · Six new pairs of isoquinoline alkaloid enantiomers, designated as yanhusanines A–F (1–6), were isolated from an aqueous extract of Corydalis yanhusuo tubers.
[49]
N-methylcoclaurine 3′-hydroxylase (NMCH) involved in the ...
Functional characterization of (S)–N-methylcoclaurine 3′-hydroxylase (NMCH) involved in the biosynthesis of benzylisoquinoline alkaloids in Corydalis yanhusuo.
[50]
Characterization of CYP82 genes involved in the biosynthesis of ...
Mar 7, 2024 · In this study, Corydalis yanhusuo, a traditional Chinese medicine rich in BIAs, was investigated to identify the catalytic function of CYP82s during BIA ...<|control11|><|separator|>
[51]
Minor Alkaloids of Corydalis bulbosa, Structure of Bulbodione
These six alkaloids had not been detected in our initial study of the plant. The structure of buldodione was elucidated on the basis of spectral data and ...Missing: tubers | Show results with:tubers
[52]
High yield extraction method for and products of corydalis plants
[0007] The alkaloids contained in Corydalis Yanhusuo are believed to possess significant bioactivity and at least include bulbocapnine, tetrahydropalmatine (THP) ...
[53]
Hendersines J–M: Isoquinoline alkaloids from Corydalis hendersonii ...
The genus Corydalis, the largest within the Papaveraceae family, serves as a rich source of bioactive isoquinoline alkaloids (Deng et al., 2021, 2023).
[54]
Development and Validation of a HPLC-ESI-MS/MS Method for ...
Mar 21, 2018 · Therefore, the major purpose of this study was to develop a rapid and sensitive HPLC-ESI-MS/MS method for the simultaneous quantification of ...Missing: rhizomes | Show results with:rhizomes
[55]
Large variability in the alkaloid content of Corydalis yanhusuo ...
Jan 14, 2025 · A systematic analysis of a CY alkaloid extract showed effective attenuation of acute, inflammatory, and neuropathic pain in animal models ...<|separator|>
[56]
Chemical Characterization of Corydalis chaerophylla D.C. Extracts ...
Nov 14, 2023 · This genus is abundant in isoquinoline alkaloids, which serve as a chemical defense against different microorganisms and herbivores.
[57]
Phytochemical Composition and Antimicrobial Activity of Corydalis ...
Aug 7, 2020 · Among the non-alkaloid compounds, there were: three carboxylic acids, two hydroxycinnamic acids, one quinic acid ester, one phenolic aldehyde ...Missing: terpenoids | Show results with:terpenoids
[58]
Flavonoid glycosides and isoquinolinone alkaloids from Corydalis ...
Flavonoid glycosides and isoquinolinone alkaloids from Corydalis ... kaempferol and quercetin were isolated from the whole plant of Corydalis bungeana Turcz.
[59]
Chemical constituents and antioxidative, anti-inflammatory and anti ...
Oct 1, 2021 · The study aimed to investigate the similarities and differences in the chemical constituents and biological activities between wild and cultivated Corydalis ...Missing: terpenoids | Show results with:terpenoids<|control11|><|separator|>
[60]
(PDF) Phytochemical Composition and Antimicrobial Activity of ...
Aug 6, 2020 · lutea (1036–1934 µg/g d.w.). Moreover, considerable amounts of coptisine (1526 µg/g) and quercetin (3247 µg/g) were detected in the aerial parts ...
[61]
Seasonal variations of natural products in European herbs
Jan 10, 2022 · The present review gives an overview about the status of research on seasonal variation of natural products in herbs growing in or grown in Europe.
[62]
[A new nor-sesquiterpene glycoside from Corydalis edulis] - PubMed
This study is to investigate the chemical constituents from the whole plant Corydalis edulis. The chemical constituents were separated and purified.Missing: terpenoids | Show results with:terpenoids
[63]
A new nor-sesquiterpene glycoside from Corydalis edulis
Aug 7, 2025 · This study is to investigate the chemical constituents from the whole plant Corydalis edulis. The chemical constituents were separated and ...
[64]
Separation and purification of alkaloids and phenolic acids from ...
Sep 22, 2023 · ... phenolic acids as ferulic acid(2), isoferulic acid(3), were successfully obtained using these three different CCC modes with the purities ...
[65]
Scent profiles of flower colour morphs of Corydalis cava ...
Twenty-seven compounds, including monoterpenes, benzenoids, phenylpropanoids and nitrogen-containing compounds were present in the scent samples. Scent profile ...
[66]
Scent profiles of flower colour morphs of Corydalis cava ...
The spectrum of flower scents highlights the importance of monoterpenes (93% in C. cirrhosa and 99% in C. flammula) as the major components identified in ...
[67]
Investigating the Components Change of Steamed Corydalis ...
Aug 12, 2025 · During 1–10 min, changes in volatile components (VOCs) were measured by headspace gas chromatography-ion mobility spectrometry (HS-GC-IMS) and ...
[68]
Corydalis - an overview | ScienceDirect Topics
The dried tuber of Corydalis yanhusuo W.T. Wang is used in traditional Chinese medicine for pain relief, anticancer effects, and the enhancement of vital energy ...
[69]
A Review of the Traditional Uses, Botany, Phytochemistry ...
Sep 30, 2020 · Corydalis yanhusuo alkaloids were shown to protect against coronary heart disease and arrhythmia. High concentrations of tertiary amine base and ...
[70]
Corydalis – Health Information Library | PeaceHealth
In Traditional Chinese Medicine, corydalis is said to invigorate the blood, move qi (energy that travels through the body), and alleviate pain, including ...
[71]
Pain: Novel Analgesics from Traditional Chinese Medicines ...
l-Tetrahydropalmatine (l-THP) possesses powerful analgesic ... dopamine D2 receptor in clinical trials [17] . ... pain scores compared with placebo. Meta ...
[72]
A Comprehensive Review on the Chemical Properties, Plant ...
These studies suggested that THP is a promising compound for treating dysmenorrhea, drug addiction, inflammatory diseases, neuropathic pain, cancer, brain edema ...Missing: VAS | Show results with:VAS
[73]
Corydalis | Herbs | Herbal Reality
Sep 24, 2024 · By eliminating qi and blood stasis, corydalis alleviates pain throughout the body, especially that which has arisen from an obstructive origin.
[74]
Can Corydalis Help With Pain and Relaxation? - Verywell Health
Oct 15, 2025 · Lab studies showed that the chloroform extract in Corydalis yanhusuo might have antibacterial and antifungal effects. 8. Animal and lab ...Uses · Side Effects · Precautions · Dosage
[75]
Corydalis saxicola Bunting: A Review of Its Traditional Uses ...
Jan 13, 2023 · When applied in traditional Chinese medicine, it is used to treat various diseases including hepatitis, abdominal pain, and bleeding haemorrhoids.
[76]
Recent Advances in Alkaloids from Papaveraceae in China - MDPI
The total alkaloids of Corydalis saxicola bunting have been found to exhibit hepatoprotective and preventive effects against liver diseases, particularly in the ...
[77]
Corydalis: Health Benefits,Side Effects,Uses,Dose - Scigroundbio
Aug 8, 2023 · For pain relief - 100-200mg corydalis extract standardized to 10% alkaloids, 2-3 times per day. · For depression/anxiety - 100-150mg extract 2-3 ...
[78]
US11235014B2 - Herbal composition for the treatment of headache
Provided herein are custom therapeutic compositions combining select Chinese herbs and strains of Cannabis, methods of making the compositions, ...Missing: 0.2-0.35% | Show results with:0.2-0.35%
[79]
The Role of Traditional Chinese Medicinal Plants in the ...
Oct 18, 2025 · Systematic reviews and meta-analyses specifically focused on Corydalis yanhusuo are scarce, and no high-quality, large-scale RCTs have yet ...
[80]
Impact of Chinese Herbal Medicine on American Society and Health ...
Feb 27, 2014 · While herbs are considered drugs in China, herbs are consumed in the USA as nutritional or food supplements without necessary warning labels on ...
[81]
Corydalis Yanhusuo - Uses, Side Effects, and More - WebMD
It has most often been taken by mouth three times daily before meals for up to 4 weeks. There isn't enough reliable information to know what an appropriate dose ...
[82]
Herbal- and Dietary-Supplement-Induced Liver Injury - ResearchGate
Feb 13, 2024 · Recent FDA warnings ... supplements with adverse effects, as well as the need for better regulation and clinical.
[83]
https://www.researchgate.net/publication/378222389_Herbal-_and_Dietary-Supplement-Induced_Liver_Injury_A_Review_of_the_Recent_Literature
[84]
Corydalis Growing Guide - Farmer Bailey
Corydalis Growing Guide ; Family, Papaveraceae ; Life Cycle, Herbaceous Perennial ; Format, 32-cell plug tray ; Plug Care, Transplant plugs quickly after arrival, ...Missing: annual biennial
[85]
Gardening 101: Corydalis - Gardenista
Jul 23, 2020 · Corydalis grows in any type of well-drained soil, in a sheltered or exposed place. Sun to dappled shade preferred. Snails and slugs enjoy its cool, leafy ...
[86]
The jewel-like Corydalis is perfect for dainty colour in the garden
May 7, 2025 · The Corydalis genus is a treasure trove of diminutive, jewel-like annual and perennial species, the vast majority of which reside in China ...
[87]
perennials - c - bluetenreich-nurserys Webseite!
Corydalis flexuosa x omeiana 'Craigton Blue' This variety was a breakthrough in Corydalis breeding, as it was the first to combine the insensitivity of C. ...
[88]
Corydalis x 'Craigton Blue'
Apr 21, 2021 · Both of it's parents originate from the higher elevations of the forests of Sichuan Province, China. As such, warm, wet summers on fertile ...
[89]
[PDF] AGM Plants December 2024 © RHS – ORNAMENTAL
AGM Plants December 2024 © RHS – ORNAMENTAL. Corydalis (Papaveraceae). Key to hardiness ratings. H1a tropical: heated greenhouse; more than 15C. H4 hardy ...Missing: market | Show results with:market
[90]
https://kindheartsandcorydalis.co.uk/corydalis-x-craigton-blue/
[91]
Corydalis and Drug-Induced Liver Injury: A Series of 2 Cases - NIH
Dec 21, 2023 · We present 2 cases of corydalis-induced hepatotoxicity. An asymptomatic female patient exhibited a rise and fall of her transaminases coinciding ...
[92]
Corydalis aurea - USDA Forest Service
GENERAL DISTRIBUTION: Scrambled eggs is distributed from Quebec west to Alaska ... Germination of seeds of other corydalis species (C. sempervirens) is ...
[93]
[PDF] Indiana Plants Poisonous to Livestock and Pets - Purdue University
If excessive amounts are ingested, vomiting and diarrhea can result, but the signs are self-limiting. Catnip can be considered as a legal recreational drug for ...
[94]
Electrophysiological effects of protopine in cardiac myocytes
Protopine (Pro) from Corydalis tubers has been shown to have multiple actions on cardiovascular system, including anti-arrhythmic, anti-hypertensive and ...
[95]
Is Incised fumewort Poisonous - Toxic - PictureThis
Sep 11, 2024 · Individuals who ingest parts of incised fumewort may experience gastrointestinal disturbances, such as nausea, vomiting, and diarrhea.<|separator|>
[96]
Biosynthesis of benzylisoquinoline alkaloids in Corydalis bracteata
It was found that all organs of C. bracteata contained high levels of BIA, the highest concentrations being detected in underground tuber buds in early autumn.
[97]
The Use of Activated Charcoal to Treat Intoxications - PMC
The administration of activated charcoal is indicated to treat moderately severe to life-threatening intoxication. It should be carried out as soon as possible, ...
[98]
Corydalis Plant Growing & Care Guide for Gardeners - Gardener's HQ
Nov 22, 2023 · Requirements: Partial shade. Good drainage. Soil pH 5.5 to 8. Rich soil. Humus rich. Moist soil. Supply leaf mold. Regular watering. Some ...
[99]
Corydalis lutea - Plant Finder - Missouri Botanical Garden
Prefers rich, moist soils that never dry out in part shade, however drainage must be good and incorporating gravel into the soil may benefit a planting. Wet ...
[100]
https://www.missouribotanicalgarden.org/PlantFinder/PlantFinderDetails.aspx?kempercode=y840
[101]
Corydalis solida|solid-rooted fumewort/RHS Gardening
Cultivation. Grows best in well-drained moderately fertile soil. May tolerate partial shade ; Propagation. Propagate by seed sown in containers in an open frame ...
[102]
Growing Corydalis solida & allies from seeds - Botanically Inclined
Mar 6, 2021 · To start from the beginning: you need to sow fresh seeds or seeds that have been kept moist. The seeds are ready sometime in late May/June in our climate.Corydalis Spring Seedlings · Corydalis And Other Sowings · Corydalis Malkensis MixMissing: guide partial pH division<|separator|>
[103]
Growing And Propagating Corydalis Plants - Gardening Know How
Feb 13, 2023 · It prefers a neutral or alkaline pH soil as well. Water often enough to keep the soil moist and feed the plants with a shovelful of compost or a ...
[104]
Corydalis flexuosa|blue corydalis/RHS Gardening
Cultivation. Grow in moderately fertile, humus-rich soil ; Propagation. Propagate by seed sown in containers in an open frame when ripe or by division in autumn ...
[105]
What Are Common Problems with Fern-leaved corydalis? - PictureThis
Nov 13, 2024 · ... rot ... Managing pests and diseases in Fern-leaved corydalis requires an integrated approach. Begin by manually removing visible pests like slugs ...
[106]
Prevent Slugs and Snails from Feasting on your Hostas - Gardenia.net
Slugs and snails are the most troublesome pests to hostas. ... Avoid overhead watering as it can seriously damage the beautiful leaves, causing them to rot and ...
[107]
What You Should Know About Corydalis lydica - Greg
To minimize irritation risk, wear gloves when handling Corydalis lydica. ... Next, let's delve into its toxicity to pets, particularly dogs. Toxicity to Dogs.Missing: livestock | Show results with:livestock
[108]
Pet-Safe Spring Gardening Tips | The Animal Health Foundation
AND if ingested in ...Missing: gloves | Show results with:gloves
[109]
Conservation impacts of commercial cultivation of endangered and ...
Farming overharvested species is a conservation strategy that can meet growing market demand and conserve wild populations of the target species.Missing: sustainable Corydalis ethical nurseries
[110]
Connecticut Garden Journal: Bring The Wild Corydalis To Your ...
Mar 8, 2018 · Corydalis is a poppy family wildflower related to bleeding hearts. It grows wild in open areas but also can be cultivated in the garden.