Fact-checked by Grok 2 weeks ago

Ear canal

The ear canal, also known as the external auditory canal or meatus, is a tubular passage in the that connects the auricle (pinna) to the tympanic membrane (eardrum), measuring approximately 25 mm in length and 7.5 mm in diameter in adults. It consists of an outer cartilaginous portion, about one-third of its length, supported by continuous with the auricle, and an inner bony portion, comprising the remaining two-thirds, formed by the . The canal follows a slightly curved (sigmoid) path, directed slightly upward, backward, and medially, and is lined with thin, that migrates outward to facilitate self-cleaning. This structure plays a crucial role in audition by funneling and amplifying sound waves from the external environment toward the tympanic membrane, enhancing and frequency detection, particularly for frequencies between 2-5 kHz due to the of its dimensions. Additionally, the ear canal protects the middle and from foreign particles, water, and microorganisms through the production of by specialized glands in the cartilaginous region, which has and lubricating properties. The canal develops embryologically from the first pharyngeal cleft, canalizing by around 16 weeks of , and its unique mammalian configuration—deeper and more protected than in other vertebrates—supports both acoustic efficiency and mechanical defense. Clinically, the ear canal is susceptible to conditions such as (swimmer's ear), cerumen impaction, and congenital atresias, which can impair hearing or cause pain; proper examination requires straightening the canal by pulling the auricle upward and backward in adults. Its anatomy also influences surgical approaches, such as in , where preserving the canal's integrity is essential for postoperative auditory function.

Anatomy

Gross anatomy

The ear canal, also known as the external auditory , is a tubular passageway in the external ear that extends from the of the auricle to the tympanic membrane, measuring approximately 25 mm in length and 7.5 mm in diameter in adults. It serves as the primary conduit for sound waves to reach the tympanic membrane. Structurally, the ear canal is divided into an outer cartilaginous portion, comprising about one-third of its length and formed by that provides flexibility and continuity with the auricle, and an inner bony portion, making up the remaining two-thirds and sculpted from the for rigid support. The canal follows a slight S-shaped , narrowing at the —the junction between the cartilaginous and bony sections—and is oriented inward, slightly upward, and backward from its external opening near the mastoid process. Its lining is a thin layer of continuous with that of the tympanic membrane, featuring hair follicles for trapping debris, as well as sebaceous and ceruminous glands concentrated in the cartilaginous part that contribute to cerumen production. Anatomical variations exist, including sex differences where the canal tends to be longer in males than in females. Age-related changes are also notable, with the canal being shorter, narrower, and straighter in infants compared to adults. In terms of spatial relations, the ear canal lies lateral to the tympanic membrane and medial to the auricle, with its anterior wall in close proximity to the via the of Huschke and its external opening adjacent to the .

Microscopic anatomy

The of the external auditory canal consists of , which is keratinized throughout most of its length to provide a protective barrier against mechanical and microbial insults. Near the tympanic membrane, this transitions to a thinner, less keratinized form, ensuring continuity with the external layer of the tympanic membrane while minimizing interference with sound transmission. A is the migratory pattern of the , where surface cells move laterally from the tympanic membrane toward the canal's external opening at a rate of approximately 0.05 mm per day, facilitating the self-cleaning process by transporting debris outward. Beneath the epidermis lies the dermis, a layer of dense irregular connective tissue rich in collagen and elastic fibers, which houses blood vessels, sensory nerves, and adnexal structures such as hair follicles and glands. Hair follicles are prominent in the outer cartilaginous portion, featuring thicker, coarser hairs that aid in filtering particles, but they diminish and are absent in the inner bony segment. The subcutaneous layer, comprising loose connective tissue and adipose elements, is well-developed in the cartilaginous outer third, providing cushioning and support for glandular elements, whereas it is absent in the bony inner two-thirds, where the skin adheres directly to the periosteum. The ear canal contains specialized exocrine glands embedded in the , primarily ceruminous glands—modified sweat glands that secrete cerumen—and associated sebaceous glands that contribute to the mixture. Ceruminous glands are coiled tubular structures with a secretory of cuboidal to columnar cells, and their density is highest in the outer third of the canal, decreasing toward the medial bony portion. Sensory innervation of the ear canal arises from branches of the (from the mandibular division of the , CN V3) for the anterior and superior regions, the auricular branch of the (CN X) for the inferior and posterior aspects, and contributions from the (CN VII) via its nervus intermedius. Vascular supply derives from branches of the , including the superficial temporal artery anteriorly and the posterior auricular artery posteriorly, forming a rich submucosal plexus that nourishes the tissues. Lymphatic drainage primarily follows the vascular pathways, directing to preauricular and anteriorly and superiorly, and to retroauricular (mastoid) and superficial cervical nodes posteriorly and inferiorly.

Development and physiology

Embryonic and postnatal development

The external auditory canal (EAC) originates during embryonic from the first branchial groove, an ectodermal invagination that forms the primary canal pit by approximately week 4 of , with contributions medially from the tubotympanic recess derived from the first pharyngeal pouch. By week 6, a solid epithelial core known as the meatal plug forms and extends inward, creating a temporary that undergoes canalization through and vacuolization, establishing a patent lumen by around 18 weeks; failure of this recanalization process results in congenital . The cartilaginous portion of the EAC develops from of the second , while the bony segment ossifies from tissues associated with the first , with typically occurring around the time of birth and continuing postnatally. Postnatally, the EAC undergoes significant growth, reaching near-adult length and diameter by ages 5 to 7 years, accompanied by increased curvature; during , further maturation includes enhanced hair growth within the canal for added protection. In the elderly, age-related leads to narrowing and reduced elasticity of the canal walls, potentially contributing to cerumen impaction and infections. Congenital anomalies such as (partial narrowing) and (complete absence) of the EAC arise primarily from disruptions in the canalization of the meatal plug or abnormal development, with an incidence of approximately 1 in 10,000 to 20,000 live births; these conditions are often unilateral and associated with (underdeveloped pinna) or syndromes like (oculo-auriculo-vertebral spectrum). Evolutionarily, the mammalian EAC represents an adaptation derived from the inward migration of the reptilian tympanic membrane, elongating the canal to enhance and protection in terrestrial environments.

Functions in hearing and protection

The ear canal plays a crucial role in auditory by amplifying sounds through . Its conical shape and average length of approximately 25 mm in adults create a quarter-wavelength that peaks in the 2-5 kHz range, which corresponds to key speech consonants, providing a of 10-15 to enhance audibility. This amplification is essential for clear perception of frequencies, improving signal-to-noise ratios in everyday listening environments. In sound localization, the open configuration of the ear canal enables the detection of interaural time differences (ITDs), where sounds arriving from one side reach the contralateral ear slightly later due to the head's width, aiding in pinpointing . Additionally, the ear canal contributes to the (HRTF), which filters high-frequency cues through interactions with the pinna and canal entrance, providing monaural spectral information for and front-back . The ear canal serves as a protective barrier, with its and cerumen forming a waterproof seal that traps water, dust, and debris, preventing their ingress to the vulnerable structures. Cerumen's properties, including and , further inhibit microbial growth by maintaining an acidic pH and directly bactericidal effects against common pathogens like Staphylococcus aureus and Pseudomonas aeruginosa. This dual mechanical and chemical defense reduces infection risk in the external auditory canal. Self-cleaning mechanisms in the ear canal involve epithelial migration, where surface cells move outward in a conveyor-belt at a rate of 0.05-0.1 mm per day, transporting desquamated , cerumen, and entrapped particles toward the auricle for natural expulsion. This process ensures without manual intervention, originating from the tympanic membrane and radiating laterally. The ear canal also contributes to , maintaining a stable microenvironment near body temperature (approximately 37°C) that supports optimal sound conduction and protects against thermal stress, with indirect ties to upper airway conditioning via nasopharyngeal connections. Sensory innervation, primarily from the auriculotemporal branch of the (V3) and the auricular branch of the (CN X), provides sensation to the canal and contributes to protective reflexes, such as tensor tympani during jaw movements like . This feedback integrates somatosensory inputs for coordinated responses.

Cerumen and maintenance

Composition and production of cerumen

Cerumen, commonly known as , exists in two primary types: and . The type is sticky and ranges in color from honey-yellow to brown, while the type is brittle and grayish-white. The type predominates in populations of and descent, whereas the type is prevalent in East Asian populations, affecting 80-95% of individuals. This dimorphism is determined by a (SNP) rs17822931 (c.538G>A) in the gene on ; the G (GG or GA ) produces cerumen, while the homozygous A (AA ) results in cerumen. The biochemical composition of cerumen primarily consists of desquamated and glandular secretions, with approximately 60% derived from shed skin cells. The remaining components include (approximately 50% of dry weight), such as saturated and unsaturated long-chain fatty acids, (around 7%), and (around 6%), wax esters, and triacylglycerols. Additional elements encompass water, peptides, lysosomes containing enzymes like , and immunoglobulins such as secretory IgA. Cerumen is produced by the ceruminous glands, which are modified sweat glands, and sebaceous glands located in the outer third of the external auditory canal. These glands secrete a mixture of and proteins that combine with exfoliated epithelial cells and to form cerumen, maintaining an acidic ranging from 5.2 to 7.0, which contributes to its protective qualities. Production occurs continuously throughout life, with variations influenced by and environmental factors. Genetic and ethnic variations in cerumen type extend beyond appearance to physiological effects; the dry type (AA genotype) is associated with reduced axillary body odor due to impaired transport of odor precursors by the non-functional ABCC11 protein in apocrine glands. This variant has undergone positive natural selection in East Asian populations, potentially linked to adaptation to colder climates, as evidenced by its correlation with higher latitudes. In terms of biological significance, cerumen supports ear canal health through , lubricating, and properties. It contains and secretory IgA, which exhibit bactericidal activity against common pathogens like and by disrupting microbial cell walls and neutralizing toxins. Additionally, cerumen demonstrates effects, inhibiting growth of and species through its acidic environment and lipid components that limit fungal adhesion and proliferation. These attributes, combined with its emollient nature, prevent dryness, facilitate epithelial migration, and form a waterproof barrier against external irritants.

Self-cleaning mechanisms

The ear canal maintains through a dynamic epithelial , where stratified squamous epithelial cells originating from the umbo of the tympanic membrane move outward in a continuous sheet, resembling conjunctival epithelial flow. This occurs at an average rate of approximately 0.1 mm per day (100 μm/day) across the tympanic membrane and into the external auditory canal, carrying desquamated , cerumen, and debris laterally toward the ear opening. The completes a full cycle across the tympanic membrane in roughly 2–3 weeks, with the canal portion extending the overall turnover time to several months depending on canal length. Synergizing with this migration, jaw movements during chewing and talking induce a peristaltic-like action in the canal's soft tissues, propelling cerumen and accumulated material outward more efficiently. This mechanical assistance ensures that even in the absence of manual intervention, debris is gradually expelled from the canal. Cerumen plays a central role in this mechanism by forming a sticky matrix that traps environmental dust, , and dead cells shed from the canal walls, with the desquamation rate of closely matching the pace of epithelial to prevent buildup. As the cerumen-laden sheet advances, it maintains canal patency without requiring external cleaning. The cerumen's slightly acidic , typically ranging from 5.2 to 7.0, further enhances self-cleaning by creating an environment that inhibits growth, such as , complementing the physical expulsion. Disruptions to these mechanisms can impair hygiene; for instance, individuals with dry cerumen (genetically determined by the allele) experience flaking that may scatter debris if migration slows, while wet cerumen, being more adhesive, increases the risk of impaction under similar conditions. This self-cleaning system is conserved across mammals, with epithelial migration present in species like dogs and , though humans exhibit enhanced efficiency potentially linked to upright posture facilitating gravity-assisted expulsion.

Disorders and conditions

Infections and inflammatory conditions

Infections and of the ear canal encompass a range of microbial and non-infectious disorders that lead to , often exacerbated by the canal's narrow, moist which traps and . These conditions primarily affect the skin lining the external auditory canal, resulting in symptoms such as , itching, and . Otitis externa, also known as swimmer's ear, is the most common acute infection, typically caused by bacterial pathogens including and . It presents with intense ear pain, tenderness, , , and purulent discharge, often worsened by jaw movement or pressure on the tragus. Risk factors include prolonged exposure to water, such as from or humid environments, as well as local from swabs or aggressive cleaning. Chronic otitis externa differs from the acute form and may manifest as persistent due to underlying dermatological issues like eczematous, seborrheic, or psoriatic conditions affecting the canal skin. Fungal infections, termed , are more prevalent in chronic cases, with species accounting for 60–90% of such etiologies, leading to symptoms like itching, scaling, and a sensation of fullness in the . Allergic reactions in the ear canal often arise as , triggered by allergens such as in earrings or components in hair products that come into direct contact with the skin. This condition contributes significantly to inflammatory cases, with identified in 40–58% of patients presenting with in clinical studies. Viral infections can also involve the ear canal, notably herpes zoster oticus, which constitutes upon reactivation of the varicella-zoster virus in the , causing vesicular eruptions in the canal alongside in many cases. Autoimmune disorders like target the cartilaginous framework of the ear canal, resulting in recurrent episodes of painful, erythematous swelling that spares the ear lobe. Epidemiologically, ear canal infections occur more frequently in humid climates, where moisture promotes bacterial and fungal growth, and are elevated among individuals with due to impaired local immunity. In immunocompromised patients, particularly elderly diabetics, acute infections can progress to malignant otitis externa, a necrotizing complication involving skull base invasion by pathogens like .

Obstructions, trauma, and other pathologies

Cerumen impaction occurs when accumulates and hardens, obstructing the ear canal. Common causes include the use of swabs, which push wax deeper into the canal, and the presence of hearing aids, which can trap wax and impair natural migration. Symptoms typically include , , ear fullness, itching, and pain, though severe complications like vertigo or can arise if untreated. The prevalence of cerumen impaction is approximately 5% in healthy adults and up to 10% in children, with higher rates—exceeding 30%—among older adults in institutional settings. Foreign bodies in the ear canal are a frequent issue, particularly in children, where small objects like beads, pebbles, or commonly lodge due to exploratory play or accidental entry. may cause additional distress through movement, potentially leading to secondary irritation. Removal attempts carry risks, including canal lacerations, bleeding, tympanic membrane , and increased patient anxiety, especially if multiple efforts are needed or if the object is deeply embedded. Trauma to the ear canal can result from mechanical injuries such as lacerations caused by cotton swabs, which may abrade the sensitive or the tympanic membrane. Blast injuries from explosions or sudden pressure changes, like slaps to the ear, often lead to tympanic membrane and canal hemorrhage due to rapid pressure differentials. Thermal burns, typically from hot liquids or objects contacting the canal, can cause epithelial damage and scarring. Iatrogenic may occur during otoscopy or , resulting in abrasions or if excessive force is applied. Neoplasms of the ear canal include benign and malignant types, with exostoses and osteomas being the most common benign lesions. Exostoses often develop from repeated cold water exposure, such as in surfers, leading to multiple bony growths that narrow the canal and cause or recurrent infections. Osteomas are solitary, slow-growing bony tumors, typically asymptomatic unless they obstruct the canal. Malignant neoplasms, such as , are rare, accounting for less than 0.2% of head and neck cancers, and are often linked to chronic inflammation or sun exposure, presenting with , discharge, or involvement. Cholesteatoma involving the ear canal can be congenital, arising from embryonic epithelial rests, or acquired, resulting from retraction pockets or chronic that allows debris to accumulate and erode canal structures. These lesions may extend into the canal, causing bony erosion, , and potential complications like if untreated. Vascular anomalies in the ear canal, such as hemangiomas, are rare benign tumors composed of proliferating blood vessels, most commonly affecting infants and potentially causing , bleeding, or recurrent infections due to their location. These lesions are typically or cavernous in type and may involute spontaneously, though intervention is required if they obstruct the canal or cause cosmetic concerns.

Clinical management

Diagnostic approaches

Diagnosis of ear canal conditions begins with a detailed history to identify symptoms and risk factors. Common presenting symptoms include (otalgia), , discharge, itching, or fullness in the ear, which may indicate , , or obstruction. Risk factors such as frequent swimming, , or prior ear trauma are also elicited, as they predispose to conditions like or exostoses. This initial assessment guides subsequent and targeted testing. Otoscopy remains the cornerstone of ear canal evaluation, involving direct visualization of the external auditory canal and tympanic membrane using an with a speculum. It allows detection of abnormalities such as , , debris, cerumen impaction, or foreign bodies, which suggest or . Pneumatic otoscopy enhances this by assessing tympanic membrane mobility through gentle air ; reduced mobility may indicate underlying involvement secondary to canal . Findings like canal narrowing or lesions prompt further investigation. For more precise assessment, microscopic otoscopy employs an operating to provide magnified views (up to 40x) of the ear canal, facilitating detailed evaluation of cerumen, subtle lesions, or . This technique is particularly useful in outpatient settings for safe removal of impacted material or sampling under direct vision. Imaging modalities are employed when otoscopy reveals complex . Computed tomography () is preferred for bony abnormalities, such as exostoses or erosion, offering high-resolution depiction of canal anatomy and extent of involvement. (MRI) excels in evaluating tumors or extending beyond the canal, providing contrast-enhanced details of or neoplasms. Audiometry quantifies hearing impairment associated with ear canal disorders, particularly conductive hearing loss from obstructions or stenosis. Pure-tone audiometry measures thresholds across frequencies, identifying air-bone gaps that localize the deficit to the external or middle ear. This test complements otoscopic findings by assessing functional impact. Microbiological cultures from canal swabs are essential for confirming infectious etiologies, especially in refractory otitis externa, where pathogens like Pseudomonas aeruginosa are isolated to guide antibiotic selection. Biopsy with histopathology is indicated for suspicious lesions or neoplasms, providing definitive diagnosis of malignancies like squamous cell carcinoma through tissue sampling. Endoscopy, using fiberoptic or rigid scopes, enables visualization of the deep ear canal in cases of or incomplete views on standard otoscopy. It offers a wide field and illuminated assessment, aiding in the detection of hidden pathologies without general . This approach is valuable for both diagnostic and minor therapeutic interventions.

Treatment and preventive measures

Treatment of ear canal disorders typically follows diagnostic confirmation to target specific pathologies such as infections, obstructions, or trauma. For cerumen impaction causing symptoms or obstructing examination, removal methods include irrigation with warm water, suction, or curettage, performed by trained clinicians to avoid complications. Irrigation involves directing a stream of body-temperature water into the ear canal to flush out wax, while suction uses a low-pressure device to aspirate cerumen, and curettage employs a curette for manual scraping. These procedures are contraindicated in cases of perforated eardrum to prevent further damage or infection. The American Academy of Otolaryngology—Head and Neck Surgery (AAO-HNS) recommends against routine cerumen removal in asymptomatic patients whose ears can be adequately examined, emphasizing intervention only when beneficial. Pharmacological treatments address infections effectively in most cases. For , topical antibiotics combined with corticosteroids, such as otic drops, are standard to combat bacterial pathogens like and reduce inflammation, typically administered for 7-10 days. In , topical antifungals like clotrimazole or miconazole are preferred, applied directly to the canal to eradicate fungi such as species, often for 1-3 weeks. Surgical interventions are reserved for structural issues or neoplasms. Meatoplasty widens a stenotic ear canal by excising conchal and enlarging the , improving and hearing. Excision of tumors or osteomas involves transcanal removal to alleviate obstruction, with excellent if cases are monitored. Canalplasty reconstructs the canal post-trauma through drilling and grafting to restore patency and function. Advanced techniques include CO2 for exostoses, offering precise removal with minimal damage to surrounding tissue. For severe malignant , hyperbaric serves as an adjunct to antibiotics, enhancing tissue oxygenation to combat in refractory cases. Preventive measures focus on reducing risk factors for common issues. Individuals should avoid inserting Q-tips or similar objects into the ear canal, as this can push cerumen deeper, cause , or introduce leading to impaction or . Swimmers are advised to use earplugs to block water entry and prevent , known as swimmer's ear. After bathing or swimming, ears should be dried thoroughly by tilting the head and gently toweling the to minimize moisture retention.

References

  1. [1]
    Anatomy and Development of the Mammalian External Auditory Canal
    This review focuses on the often-neglected outer ear, specifically the external auditory meatus (EAM), or ear canal.
  2. [2]
    Anatomy, Head and Neck, Ear - StatPearls - NCBI Bookshelf
    The external ear is the visible part of the hearing apparatus. It is comprised of the auricle (pinna) and external auditory canal.
  3. [3]
    Physiology, Ear - StatPearls - NCBI Bookshelf
    This meatus has a tube form and extends inward to end in the tympanic membrane. Two-thirds of this canal are cartilaginous, and the last third is bone, and the ...
  4. [4]
    External auditory canal | Radiology Reference Article
    Aug 30, 2025 · Gross anatomy​​ The external auditory canal is typically 2.5 cm in length and is S-shaped. The lateral one-third is bounded by a ...External auditory canal atresia · External ear anatomy... · EAC cholesteatomaMissing: dimensions curvature
  5. [5]
    External acoustic meatus: Anatomy and function - Kenhub
    Mar 5, 2024 · In adults, this canal measures approximately 2-3 cm in length and extends medially and slightly upward to reach the tympanic membrane (eardrum), ...Missing: gross dimensions divisions curvature
  6. [6]
    External Auditory Canal: Computed Tomography Analysis and ... - NIH
    Abbreviations: EAC, external auditory canal. At the isthmus of the EAC (narrowest point of the bony EAC), the mean vertical length was 6.8 ± 0.97 mm (range ...
  7. [7]
    Conventional Amplification for Children and Adults with Severe-to ...
    In addition, the EAC of infants and children is shorter and straighter than the EACs of adults. The EAC is not considered to be adult in size until 9 ...
  8. [8]
    Histology, Ear - StatPearls - NCBI Bookshelf - NIH
    The external auditory canal also has keratinized stratified squamous epithelium that covers the external tympanic membrane as well. Cerumen is wax produced by ...Structure · Function · Tissue Preparation · Microscopy, Light
  9. [9]
    Ear - Histology at SIU - Southern Illinois University
    Jul 22, 2023 · It is sandwich of tissues, with keratinized stratified squamous epithelium facing the outer ear, non-keratinized stratified squamous epithelium ...
  10. [10]
    Anatomy, histology & grossing - Ear - Pathology Outlines
    Apr 17, 2021 · External auditory canal: lined by thin keratinized stratified squamous epithelium covering scant fibrous stroma along entire canal and covering external ...
  11. [11]
    The External Auditory Canal and Pinna | Radiology Key
    Dec 29, 2015 · Lymphatic drainage is anteriorly into the preauricular nodes, posteriorly into the mastoid nodes, and inferiorly into the subparotid nodes. All ...Pathology · Embryologic · Microtia And External...<|control11|><|separator|>
  12. [12]
    Embryology, Ear - StatPearls - NCBI Bookshelf - NIH
    Aug 8, 2023 · The external auditory canal is formed partly of cartilage and partly of bone. The internal bony segment has tiny hairs and cerumen-producing ...Introduction · Development · Cellular · Molecular Level
  13. [13]
    The aging ear: an otomicroscopic and tympanometric study - PubMed
    Ear canal volume is smaller in elderly females than elderly males, which is potentially relevant to the study of otoacoustic emissions in the elderly.<|control11|><|separator|>
  14. [14]
    External Ear Aural Atresia - StatPearls - NCBI Bookshelf - NIH
    Sep 14, 2025 · Congenital aural atresia is a developmental malformation of the external auditory canal that ranges from stenosis to complete absence of the ...
  15. [15]
    Real ear unaided gain and its relation with the equivalent volume of ...
    A compilation of studies on the resonance of the external ear indicates an average resonance frequency of 2700 Hz with an amplitude of 16.8 dB. In this ...Missing: kHz | Show results with:kHz
  16. [16]
    Noise-Induced Hearing Threshold Shift Correlated with Body Weight ...
    Nov 27, 2023 · External-ear amplification (EEA) has been shown to vary from 5–19 dB-A in large datasets of pediatric, adolescent, and adult human participants.
  17. [17]
    Auditory localization: a comprehensive practical review - Frontiers
    This acoustic filtering can be characterized by transfer functions called the Head-Related Transfer Functions (HRTFs). HRTFs are considered monaural cues ...
  18. [18]
    [PDF] echoes.pdf - Michigan State University
    interaural-differences model of sound localization is the head-related transfer function. The head-related transfer function (HRTF) is the frequency ...
  19. [19]
    Human antimicrobial proteins in ear wax
    Antimicrobial peptides in ear wax prevent bacteria and fungi from causing infections inthe external auditory canal. The role and importance of these proteins ...
  20. [20]
    Human Cerumen and its Antimicrobial Properties
    Our study demonstrated the antibacterial and antifungal properties of cerumen, which show the protective role of cerumen toward the external auditory canal. One ...Missing: scientific paper
  21. [21]
    Epithelial Migration in Open Mastoidectomy Cavities - Academia.edu
    Epithelial migration over tympanic membrane and 0.05–0.07 mm/day, this suggests that epithelial migration external canal. Arch Otolaryngol 1963;77:254–7 ...
  22. [22]
    Morphological Evidence for the Sensitivity of the Ear Canal ... - Nature
    Mar 6, 2020 · This study highlights the innervation of the ear canal with the presence of lamellar corpuscles over its entire course, and their absence in all studied ...
  23. [23]
    Air temperature in the outer ear canal - PubMed
    Under normal conditions, there was no difference between the two groups, the temperature next to the drum head being in the same range as the body temperature.Missing: inspired | Show results with:inspired
  24. [24]
    A SNP in the ABCC11 gene is the determinant of human earwax type
    The AA genotype corresponds to dry earwax, and GA and GG to wet type. A 27-bp deletion in ABCC11 exon 29 was also found in a few individuals of Asian ancestry.
  25. [25]
    Cerumen Impaction Removal - StatPearls - NCBI Bookshelf - NIH
    Production of cerumen (earwax) is a normal biological process in humans and many other mammals. Cerumen moisturizes the skin of the external auditory canal ...Missing: apocrine | Show results with:apocrine
  26. [26]
    Composition of cerumen lipids - PubMed - NIH
    The lipid fraction comprised 52% of the dry weight of cerumen and consisted of squalene (6.4%), cholesterol esters (9.6%), wax esters (9.3%), triacylglycerols ...
  27. [27]
    Insights into cerumen and application in diagnostics - PubMed Central
    A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene. BMC Genet. 2009;10:42–6. 10.1186/1471-2156 ...
  28. [28]
    KNOWLEDGE OF CERUMEN AND EFFECT OF EAR SELF ... - NIH
    Cerumen exerts a protective effect by maintaining an acidic milieu (pH of 5.2 - 7.0) in the external auditory canal whilst also lubricating the canal3,4,6. It ...
  29. [29]
    A strong association of axillary osmidrosis with the wet earwax type ...
    Aug 4, 2009 · In other words, the ABCC11 protein may play a role in the excretory function of the axillary apocrine gland. Together, these results suggest ...Missing: body | Show results with:body<|separator|>
  30. [30]
    The impact of natural selection on an ABCC11 SNP determining ...
    Oct 11, 2010 · ... ABCC11 gene determines human earwax type (i.e., wet or dry) and is one of most differentiated nonsynonymous SNPs between East Asian and ...
  31. [31]
    Human ceruminous gland: ultrastructure and histochemical analysis ...
    The ceruminous glands in the skin of the human external auditory canal are modified apocrine glands, which, together with sebaceous glands, produce the cerumen, ...Missing: rate day pH
  32. [32]
    Antibacterial and antifungal properties of human cerumen - PubMed
    Conclusions: Cerumen was demonstrated to have potential antimicrobial effects on strains of Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans.Missing: lysozyme IgA
  33. [33]
    The rate and pattern of otic epithelial migration: systematic review
    The fastest rate of epithelial migration was observed in the external auditory canal, with a mean of 144.75 μm per day, whereas the slowest epithelial migration ...Missing: 0.05-0.1 mm/
  34. [34]
    Tympanic Membrane Wound Healing and Epithelial Migration
    Dec 14, 2016 · The epithelia migrate at an average of 70–131 microns per day with some diurnal variation. The epithelial progenitor cells of the tympanic ...Missing: 0.05-0.1 mm/
  35. [35]
    Cerumen Impaction: Diagnosis and Management - AAFP
    Oct 15, 2018 · Cerumen is typically expelled from the ear canal spontaneously via a self-cleaning mechanism that is assisted by jaw movement.
  36. [36]
    Earwax (Cerumen): Types, Function & Causes - Cleveland Clinic
    Earwax (cerumen) is a waxy substance found in your ear canal. It keeps your ears hydrated and traps debris and germs that can damage your eardrum.Missing: barrier | Show results with:barrier
  37. [37]
    Signs, causes and what to do about impacted earwax - HealthPartners
    Dry earwax is usually gray or white, flaky and easily falls out of the ear. While it's less likely that you'll get impacted earwax if you have dry earwax, it's ...
  38. [38]
    Anatomy and Development of the Mammalian External Auditory Canal
    Unique anatomical adaptations, such as its migrating epithelium and cerumen glands, equip the ear canal for its function as both a conduit and a cul-de-sac.
  39. [39]
    Otitis Externa - StatPearls - NCBI Bookshelf - NIH
    Jul 31, 2023 · The most common cause of acute otitis externa is a bacterial infection. It may be associated with allergies, eczema, and psoriasis.Continuing Education Activity · Introduction · Etiology · Treatment / Management
  40. [40]
    Otitis Externa: Investigation and Evidence-Based Treatment - NIH
    More than 90% of cases of otitis externa are due to bacteria, most commonly Pseudomonas aeruginosa and Staphylococcus aureus. Polymicrobial infection is common.
  41. [41]
    Swimmer's ear - Symptoms & causes - Mayo Clinic
    Apr 15, 2025 · Risk factors · Water in the ear canal. This can be from heavy sweating, ongoing humid weather or water left in the ear after swimming. · Contact ...
  42. [42]
    Allergic Contact Dermatitis - StatPearls - NCBI Bookshelf - NIH
    Patients should be told to avoid wearing nickel-containing jewelry, use latex-free gloves, avoid hair dyes and fragrances which trigger dermatitis. Patients ...Missing: ear canal
  43. [43]
    Skin Prick Test Reactivity in Patients with Chronic Eczematous ... - NIH
    Allergic contact dermatitis has been diagnosed in 40-58% and 23.5% of patients suffering from otitis externa in two studies (1, 2). Hilen et al. (3) showed ...
  44. [44]
    Ramsay Hunt Syndrome - StatPearls - NCBI Bookshelf - NIH
    Ramsay Hunt syndrome, also known as herpes zoster oticus, is a late complication of varicella-zoster virus infection that results in inflammation of the ...Continuing Education Activity · Introduction · Pathophysiology · History and Physical
  45. [45]
    Relapsing Polychondritis - StatPearls - NCBI Bookshelf
    Relapsing polychondritis (RP) is a rare autoimmune condition which presents as recurrent episodes of cartilaginous inflammation of the auricular, nasal and ...Continuing Education Activity · Introduction · History and Physical · Evaluation
  46. [46]
    Otitis Externa, Otitis Media, and Mastoiditis - PMC - PubMed Central
    Chronic otitis externa is caused by irritation from drainage through a perforated tympanic membrane. The underlying cause is chronic suppurative otitis media. ...
  47. [47]
    Necrotizing (Malignant) Otitis Externa - StatPearls - NCBI Bookshelf
    Oct 29, 2023 · Necrotizing (malignant) otitis externa (NOE) is a severe infection that affects the external auditory canal, skull base, and temporal bone.Missing: climates | Show results with:climates
  48. [48]
    Earwax Impaction: Symptoms, Predisposing Factors and Perception ...
    The prevalence of cerumen impaction varies greatly,[16] approximately 10% of the children, 5% of normal healthy adults, up to 57% of older patients in nursing ...
  49. [49]
    Ear Foreign Body Removal - StatPearls - NCBI Bookshelf
    Jan 22, 2025 · This activity outlines the anatomy of the external auditory canal, discusses clinical presentations, and describes the management of ear foreign bodies.Missing: histology | Show results with:histology
  50. [50]
    Foreign Bodies in the Ear, Nose, and Airway
    Insects may also fly into the ear canal, causing potential harm. It has also been noted that children with chronic outer ear infections tend to place things in ...Foreign bodies in the ear · Treatment
  51. [51]
    Removal of ear canal foreign bodies in children: What can go wrong ...
    Multiple attempts at ECFB removal are associated with increased risk of pain, bleeding, patient anxiety, loss of cooperation, and serious otologic complications ...
  52. [52]
    Why Using Cotton Swabs to Clean Ears Can Result in Ear Injuries
    Apr 6, 2018 · Rose, using swabs inside the ear may lead to: Inflammation of the ear canal; Decreased hearing (temporary or long-term, depending on the injury) ...Missing: blasts thermal iatrogenic
  53. [53]
    Ear Trauma in Orlu, Nigeria: A Five-Year Review - PMC - NIH
    Ear trauma is common and mostly affects the tympanic membrane. Sudden increase in canal pressure from blows/slaps was the major mechanism of injury.Missing: burns | Show results with:burns
  54. [54]
    [PDF] Middle ear damages - B-ENT
    The eardrum and middle ear are often exposed to blunt and penetrating trauma, blasts, thermal or caustic injuries. These injuries may result in tympanic ...
  55. [55]
    Ear Foreign Body Removal in Emergency Medicine
    Jul 5, 2023 · Pain or bleeding may occur with objects that abrade the ear canal or rupture the tympanic membrane or from the patient's attempts to remove the ...
  56. [56]
    External Ear Benign Tumors - Medscape Reference
    Jun 13, 2023 · Osteomas are slow growing. These are the most common bony neoplasms of the temporal bone (exostoses are not true neoplasms). The incidence of ...
  57. [57]
    Squamous Cell Carcinoma of the External Auditory Canal and ... - NIH
    Squamous cell carcinoma of the external ear canal and middle ear are rare malignancies, often presenting in the setting of long standing chronic otitis ...Missing: osteomas | Show results with:osteomas
  58. [58]
    Middle Ear Cholesteatoma - StatPearls - NCBI Bookshelf
    Aug 9, 2024 · Middle ear cholesteatomas can be classified into 3 major types—congenital, primary-acquired, and secondary-acquired.
  59. [59]
    Cholesteatoma: Symptoms, Causes & Treatment - Cleveland Clinic
    Cholesteatoma is an abnormal growth in your middle ear behind your eardrum. It can be congenital (present from birth), but typically happens because you have ...
  60. [60]
    A Rare Vascular Tumour of the External Auditory Canal - PMC - NIH
    Haemangiomas are rare benign vascular tumours. They are relatively common in head and neck and can be classified as either capillary haemangioma, cavernous ...
  61. [61]
    Ear Hemangiomas | Children's Hospital of Philadelphia
    Hemangiomas are the most common benign tumor of infancy. Hemangiomas can occur anywhere on the body, including on and around the external ear.
  62. [62]
    Diagnosis of Ear Pain | AAFP
    Mar 1, 2008 · Other symptoms can include hearing loss, tinnitus, vertigo, taste disturbance, and decreased tearing.
  63. [63]
    Position Statement: Red Flags-Warning of Ear Disease
    Apr 21, 2021 · History of pain, active drainage, or bleeding from an ear. Sudden onset or rapidly progressive hearing loss. Acute, chronic, or recurrent ...<|separator|>
  64. [64]
    Ear Examination - StatPearls - NCBI Bookshelf
    Oct 31, 2022 · In general, abnormalities of the external and middle ears produce conductive hearing loss, and inner ear abnormalities produce sensorineural ...
  65. [65]
    Otoscopy - StatPearls - NCBI Bookshelf - NIH
    Jan 20, 2025 · Otoscopy is an essential clinical tool used to evaluate and diagnose conditions and diseases of the external and middle ear.Definition/Introduction · Issues of Concern · Clinical Significance
  66. [66]
    [PDF] Primary Care Otolaryngology
    Pneumatic otoscopy should be performed to observe the mobility of the tympanic membrane with gentle insufflation of air. Mobility may be lim- ited by scarring, ...
  67. [67]
    Otology/Neurotology - 2018 - Otolaryngology–Head and Neck Surgery
    Sep 25, 2018 · Methods: The methods used were direct assessment by microscopic otoscopy, microbiological culture, biopsy, histological examination ...
  68. [68]
    External auditory canal exostoses | Radiology Reference Article
    Oct 5, 2024 · External auditory canal exostoses, also known as surfer's ear, are benign bony overgrowths of the bony external auditory canal brought about by exposure to ...
  69. [69]
    Otolaryngologic Disorders - PMC - PubMed Central - NIH
    A temporal bone computed tomographic (CT) scan and/or magnetic resonance imaging (MRI) is performed to assess the cochlea and auditory nerves. Children who ...
  70. [70]
    Audiometry Screening and Interpretation - AAFP
    Jan 1, 2013 · When hearing loss is suspected, pure-tone audiometry may be used to evaluate hearing deficits by spot-checking certain frequencies, or to ...Abstract · Pure-Tone Audiometry · Special Considerations...
  71. [71]
    Audiogram Interpretation - StatPearls - NCBI Bookshelf - NIH
    The audiogram quantifies and visually displays a patient's degree and type of hearing loss (sensorineural, conductive, or mixed).
  72. [72]
    Diagnosis and treatment of necrotising otitis externa and diabetic ...
    Aug 28, 2018 · A superficial swab of the external ear canal is currently the accepted approach for isolating the offending pathogen in necrotising otitis ...Missing: neoplasms | Show results with:neoplasms<|separator|>
  73. [73]
    Squamous cell carcinoma of the external auditory canal
    Mar 1, 2023 · ​In addition to the biopsy-proven squamous cell carcinoma, left ear swab culture yielded Pseudomonas aeruginosa. This case showed the ...
  74. [74]
    Does ear endoscopy provide advantages in the outpatient ...
    Endoscopy allows the examiner to transfer the source of light into the cavity, despite the small size of the ear canal. When combined with the wide field of ...
  75. [75]
    Fiberoptic Video‐Otoscope | Semantic Scholar
    INTRODUCTION Video-otoscopy allows enhanced visualization of the external ear canal, the tympanic membrane, and some aspects of the middle ear to a bedside ...<|separator|>
  76. [76]
    AAO-HNSF Updated Clinical Practice Guideline: Acute Otitis Externa
    Feb 3, 2014 · Treatment for AOE includes analgesics and eardrops, which include antiseptics, antibiotics, and corticosteroids, alone or in combination.
  77. [77]
    Clinical Practice Guideline: Earwax (Cerumen Impaction) (Update)
    The primary purpose of this guideline is to help clinicians identify patients with cerumen impaction who may benefit from intervention, and to promote evidence ...
  78. [78]
    Otitis Externa: A Practical Guide to Treatment and Prevention - AAFP
    Mar 1, 2001 · Additionally, the canal is defended by a unique epithelial migration that occurs from the tympanic membrane outward, carrying any debris with it ...
  79. [79]
    Clinical Practice Guideline (Update): Earwax (Cerumen Impaction)
    The guideline is intended for all clinicians who are likely to diagnose and manage patients with cerumen impaction, and it applies to any setting in which ...
  80. [80]
    Acute otitis externa in adults: Treatment - UpToDate
    Mar 12, 2025 · Topical otic preparations: General principles · - Antibiotics · - Glucocorticoids · - Antiseptics and acidifying solutions · PAIN MANAGEMENT ...
  81. [81]
    Review of Recurrent Otomycosis and Clotrimazole in Its Treatment
    Oct 9, 2022 · Topical therapy includes the use of antifungals, of which the most commonly used drugs include clotrimazole or miconazole, often given along ...
  82. [82]
    Meatoplasty in Canal wall down Surgery: Our Experience and ... - NIH
    Meatoplasty techniques include a combination of transposed skin flaps, removal of the conchal cartilage, removal of the cartilage from the tragus or floor of ...
  83. [83]
    External Auditory Osteoma - PMC - NIH
    Osteomas of the EAC are considered benign tumors as they are non-invasive; however, they can cause significant symptoms due to mass effect and auditory canal ...
  84. [84]
    Canalplasty Periprocedural Care: Pre-Procedure Planning ...
    Oct 21, 2022 · Packing will be removed from the canal in approximately 2–3 weeks ... ear canal due to interruption of the natural epithelial migration of EAC ...
  85. [85]
    Hyperbaric oxygen therapy in malignant otitis externa: A systematic ...
    May 4, 2020 · HBOT may be an effective treatment option for refractory or advanced MOE but its efficacy remains unproven due to lack of strong scientific evidence.
  86. [86]
    Are Q Tips Bad for Your Ears - Michigan Medicine
    Jan 10, 2017 · Don't stick anything in your ear smaller than your elbow. Dig around with a cotton swab, and you'll put yourself at risk for earwax impaction.
  87. [87]
    Swimmer's Ear | Johns Hopkins Medicine
    Keep your ears as dry as possible. · Use earplugs when swimming or showering. This prevents constant moisture inside the ear. · Don't scratch or clean your ear ...
  88. [88]
    Probiotics for preventing acute otitis media in children - PMC
    However, probiotics may not benefit children prone to acute middle ear infection. Taking probiotics did not impact on the number of days of school that children ...