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Pox

Pox is a medical and historical term that emerged in the late 15th century to denote infectious diseases marked by eruptive sores or pustules on the skin, encompassing conditions such as syphilis (known as the "great pox" or la grosse verole in French), smallpox (the "small pox" or la petite verole), and later distinctions like chickenpox.^[1] The term "pox" initially arose amid European outbreaks, where syphilis was differentiated from smallpox due to the scale and severity of its skin manifestations, with the former causing more widespread and destructive lesions.^[1] Chickenpox, caused by the varicella-zoster virus, was long conflated with smallpox until English physician William Heberden provided a precise clinical description in 1767, highlighting its milder course and distinct rash progression from papules to vesicles rather than deep pustules.^[1] In contrast, true pox diseases like smallpox, cowpox, and monkeypox are caused by viruses in the family Poxviridae, large double-stranded DNA viruses that replicate in the host cell's cytoplasm and produce characteristic brick-shaped particles observable under electron microscopy.^[2] Historically, pox diseases have profoundly shaped human health and medicine; smallpox alone killed hundreds of millions over centuries until its global eradication, certified by an independent commission in December 1979 and officially declared by the World Health Organization (WHO) in 1980 following a intensive vaccination campaign launched in 1967.^[3] Cowpox played a pivotal role in this triumph, as Edward Jenner utilized its milder symptoms in 1796 to develop the first vaccine against smallpox, coining the term variolae vaccinae (cowpox) and laying the foundation for modern immunology.^[1] Syphilis, while bacterial and treatable today with antibiotics like penicillin, persisted as a major public health threat into the 20th century, often stigmatized under its "great pox" moniker.^[1] In contemporary contexts, pox-related concerns center on mpox (formerly monkeypox), a zoonotic disease caused by a Poxviridae member endemic to Central and West Africa. A global outbreak of mpox clade IIb began in May 2022, resulting in over 99,000 cases across more than 100 countries/territories by mid-2023, with fewer than 200 deaths and primarily affecting men who have sex with men.^[4] ^[5] Separately, an outbreak of the more severe clade I (particularly Ib sublineage) in Africa, predominantly the Democratic Republic of the Congo (DRC), has reported over 29,000 cases and more than 800 deaths as of September 2024.^[6] As of November 2025, the WHO continues to monitor clade I mpox surges in Africa, with over 40,000 suspected cases reported in the DRC in 2025 alone and sporadic travel-associated cases in non-endemic countries like the United States, emphasizing vaccination with modified vaccinia Ankara (MVA) and ring vaccination strategies to curb transmission, which occurs primarily through close contact, respiratory droplets, or contaminated materials.^[7] ^[8] These developments underscore the enduring legacy of pox nomenclature in virology and public health, linking ancient scourges to ongoing efforts in disease surveillance and prevention.

Infections

Poxvirus infections

Poxviridae is a family of large, double-stranded DNA viruses belonging to the nucleocytoplasmic large DNA viruses group, characterized by their brick-shaped or ovoid virions measuring 220–450 nm in length and 140–260 nm in width, with a lipoprotein surface membrane.^[9] Unlike most DNA viruses, poxviruses replicate entirely within the host cell's cytoplasm, forming viral factories that enable independent transcription and assembly without relying on nuclear machinery.^[9] The family comprises two subfamilies: Chordopoxvirinae, which infects vertebrates and includes genera such as Orthopoxvirus (e.g., variola and monkeypox viruses), Avipoxvirus, Leporipoxvirus, and Capripoxvirus; and Entomopoxvirinae, which primarily affects insects.^[10] Among human pathogens in the Poxviridae family, smallpox, caused by the variola virus (an Orthopoxvirus), was a highly contagious disease transmitted primarily through respiratory droplets or contact with contaminated materials, leading to symptoms such as high fever, severe fatigue, back pain, and a characteristic rash progressing from macules to pustules and scabs over 2–4 weeks.^[11] The disease had a case-fatality rate of up to 30% in unvaccinated individuals, with survivors often bearing permanent scars or blindness.^[12] Smallpox vaccination originated in 1796 when Edward Jenner demonstrated that inoculation with cowpox virus material protected against variola, laying the foundation for global immunization efforts.^[13] The World Health Organization's intensified eradication campaign, launched in 1967, employed targeted vaccination and surveillance, culminating in smallpox's declaration as eradicated worldwide in 1980, with the last natural case occurring in 1977.^[3] Mpox, caused by the monkeypox virus (another Orthopoxvirus), presents with symptoms resembling a milder form of smallpox, including fever, headache, muscle aches, lymphadenopathy, and a rash that evolves from flat lesions to pustules over 2–4 weeks, with transmission occurring through direct contact with infected animals or humans, bodily fluids, or contaminated surfaces.^[14] A global outbreak beginning in 2022 (clade IIb) has resulted in more than 114,000 cases across 122 countries as of July 2025, primarily through close human contact, prompting the World Health Organization to rename the disease "mpox" in 2022 to reduce stigma while retaining "monkeypox" for established contexts.^[15]^[16] The case-fatality rate for mpox is generally low at 1–3%, though higher in vulnerable populations such as children and immunocompromised individuals.^[14] Other human poxvirus infections include molluscum contagiosum, caused by molluscum contagiosum virus (Molluscipoxvirus), a common, self-limited skin infection presenting as small, pearly papules with central umbilication, transmitted through skin-to-skin contact, affecting children and adults, particularly in immunocompromised individuals.^[17] Parapoxviruses cause zoonotic infections like orf (contagious ecthyma) and bovine papular stomatitis (milker's nodules), resulting in localized pustular or nodular lesions on the hands from contact with infected sheep, goats, or cattle, typically resolving without treatment in 4–6 weeks.^[9] Tanapox, caused by tanapox virus (Yatapoxvirus), is a mild, self-limiting febrile illness with a single skin nodule, endemic to East Africa and transmitted by arthropods or direct contact with infected primates.^[9] Zoonotic poxvirus infections highlight the family's broad host range, with cowpox virus (Orthopoxvirus) serving as the original source for Jenner's smallpox vaccine due to its cross-protective mild lesions in humans, typically acquired from rodents or cats via contact or bites. Buffalopox virus, closely related to vaccinia virus, causes outbreaks in livestock in India and sporadically infects humans through milking or close contact, resulting in localized pustular lesions. Camelpox virus similarly affects camels in the Middle East and Africa, with rare human zoonotic cases presenting as mild skin infections from handling infected animals. Animal-specific poxvirus diseases include fowlpox, caused by fowlpox virus (Avipoxvirus), which manifests in birds as cutaneous lesions on unfeathered skin or diphtheritic membranes in the respiratory tract, transmitted mechanically by mosquitoes or direct contact, leading to reduced egg production and mortality in young poultry. Swinepox, induced by swinepox virus (Suipoxvirus), produces mild, self-limiting skin eruptions in pigs, particularly affecting piglets under poor management conditions, and spreads through direct contact or fomites without significant systemic involvement. Myxomatosis, resulting from myxoma virus (Leporipoxvirus), is lethal in European rabbits, causing tumor-like swellings around the eyes and genitals, fever, and respiratory distress, with transmission via arthropod vectors like fleas and mosquitoes; it is benign in native South American rabbits. Prevention of poxvirus infections relies on vaccination, exemplified by the JYNNEOS vaccine, a live-attenuated modified vaccinia Ankara (derived from vaccinia virus) approved for mpox and smallpox protection in at-risk adults, administered in two doses to induce immunity without replication in humans.^[18] For context, chickenpox is often confused with true poxvirus diseases but is caused by the unrelated varicella-zoster virus, a herpesvirus.^[9]

Other pox-like conditions

Several diseases not caused by poxviruses have been historically termed "pox" due to their pustular or vesicular rashes resembling those of smallpox, leading to early diagnostic confusion in medicine.^[19] In Renaissance Europe, physicians often misattributed eruptive skin conditions based on superficial similarities, as diagnostic tools were limited and the term "pox" broadly denoted any rash-forming illness; for instance, outbreaks of syphilis were initially lumped with viral poxes until differentiated through clinical observation.^[1] This etymological overlap persisted into early modern medicine, where symptomatic parallels overshadowed etiological distinctions.^[20] Syphilis, caused by the bacterium Treponema pallidum, emerged in Europe around the late 15th century and was dubbed the "Great Pox" to distinguish its larger, more destructive lesions from the "Small Pox" of variola virus infection.^[19] In 1530, Italian physician and poet Girolamo Fracastoro formalized the name in his seminal work Syphilis sive morbus Gallicus, a didactic poem that described the disease's progression and blamed its origin on a shepherd named Syphilus, while also noting its transmission and societal stigma.^[21] The disease advances through stages: primary syphilis features a painless chancre at the infection site; secondary syphilis involves a maculopapular rash, fever, and lymphadenopathy; and untreated cases may progress to tertiary syphilis, including neurosyphilis with neurological damage.^[22] Penicillin, introduced in the 1940s, revolutionized treatment by effectively eradicating the spirochete in early stages, rendering prior mercury- and arsenic-based therapies obsolete.^[23] Chickenpox, or varicella, results from infection with the varicella-zoster virus in the herpesvirus family, not Poxviridae, but earned its "pox" moniker in the 17th century due to its blistering rash mimicking milder forms of smallpox.^[24] Highly contagious via respiratory droplets or vesicle fluid, it primarily affects children, manifesting as fever, malaise, and crops of itchy vesicles that crust over 4–7 days.^[25] A key long-term complication is reactivation as herpes zoster (shingles) decades later, especially in immunocompromised individuals or the elderly.^[26] The live attenuated vaccine, licensed in the United States in 1995, has dramatically reduced incidence by over 90% in vaccinated populations.^[27] Rickettsialpox, caused by the bacterium Rickettsia akari, was first identified during urban outbreaks in New York City in the 1940s and named for its vesicular rash resembling chickenpox.^[28] Transmitted to humans via bites from mites (Liponyssoides sanguineus) infesting house mice, it presents mildly with fever, headache, an initial eschar at the bite site, and a sparse, non-pruritic rash that spares the palms and soles.^[29] Unlike true poxviruses, it is self-limited, resolving in 1–2 weeks without sequelae, though doxycycline shortens symptoms; the 1946–1950 epidemics affected over 500 cases in Queens, highlighting its zoonotic urban risk.^[30]

Arts, entertainment, and media

Games

Several games across various formats have incorporated "Pox" in their titles or central themes, often drawing on concepts of infection, invasion, or alien corruption within sci-fi or strategy contexts. These titles span handheld electronics, board games, and digital collectible card games, emphasizing mechanics like creature customization, cooperative disease control, and tactical battles. The 2001 handheld electronic game POX: The Game of Alien Creation, developed and published by Hasbro, allows players to create and evolve customizable alien creatures known as POX Infectors using an LCD screen and simple controls. Gameplay involves battling these creatures in single-player arena modes or multiplayer encounters via infrared communication, where stronger POX units defeat opponents and replicate themselves across devices, simulating viral spread in a sci-fi setting.^[31] The game was marketed as a portable virtual pet-style battler, with different starter units like Plasmo, Spino, and Cycro offering unique attributes for strategic depth.^[32] Pox: Save the People, a cooperative board game released in 2011 by Tiltfactor (designed by Mary Flanagan, Zara Downs, and Max Seidman), challenges 1-4 players to contain a fictional deadly disease outbreak in a community through vaccination, treatment, and resource management using cards and tokens. Players collaborate to achieve herd immunity by strategically placing cures and vaccines on a modular board representing neighborhoods, while dice rolls introduce uncertainty in disease progression; the game also serves an educational purpose, promoting understanding of public health concepts like epidemiology.^[33] An iOS adaptation followed, expanding accessibility for digital play.^[34] Poxnora, launched in 2006 by Octopi Media as an online collectible card game, blends turn-based tactics with fantasy strategy, where players build decks of "runes" (cards representing champions, spells, and relics) to command armies on a grid-based battlefield. Core mechanics include capturing font nodes for resources, deploying units with abilities influenced by the game's lore-heavy world of Poxnora—a plague-ravaged continent—though direct "infection" effects are integrated via certain rune abilities that debuff or alter enemy stats.^[35] Originally a browser-based title using Java Web Start, it evolved into a free-to-play model with optional rune purchases for deck expansion, undergoing publisher transitions to Sony Online Entertainment in 2010 and later Desert Owl Games, which revitalized its community through updates and Steam integration; reception highlights its depth as a hybrid of CCGs and miniatures games, appealing to niche strategy enthusiasts despite a steep learning curve.^[36]

Literature, film, and other works

In literature, the term "pox" frequently evokes the historical and cultural dimensions of syphilis, often termed the "Great Pox" to distinguish it from smallpox. Deborah Hayden's 2003 book Pox: Genius, Madness, and the Mysteries of Syphilis explores the disease's profound influence on prominent historical figures, including Adolf Hitler, Vincent van Gogh, and James Joyce, while tracing its broader cultural history from the Renaissance onward as a symbol of affliction and enigma.^[37] The work draws on medical records, biographies, and artistic representations to argue that syphilis contributed to episodes of genius and madness, reshaping perceptions of creativity and mental health in Western culture.^[38] Metaphorical uses of "pox" appear prominently in canonical works, serving as curses or emblems of retribution and moral corruption. In William Shakespeare's Romeo and Juliet (1597), the character Mercutio invokes "A pox on both your houses!" during a fatal brawl, using the term interchangeably with "plague" to curse the feuding Montague and Capulet families, reflecting Elizabethan anxieties over venereal diseases and societal discord. This phrase, rooted in the era's conflation of poxes with divine or contagious punishment, recurs in Victorian novels as a motif for ethical decline and social contagion. For instance, in George Gissing's New Grub Street (1891), syphilis symbolizes the erosion of masculine integrity amid economic pressures and literary commodification, linking personal vice to broader cultural decay.^[39] Similarly, Charles Dickens employs pox-like afflictions in Bleak House (1853) to illustrate moral and institutional rot, where diseases mirror the contaminating effects of poverty and injustice on the body politic.^[40] Eighteenth-century British satire further weaponized "pox" through venereal humor, portraying it as a satirical lens on class, gender, and sexuality. Noelle Gallagher's 2019 book Itch, Clap, Pox: Venereal Disease in the Eighteenth-Century Imagination analyzes how writers like Jonathan Swift and Alexander Pope used pox metaphors in poetry and prose to mock elite pretensions, associating infection with folly and hypocrisy while navigating the disease's taboo status.^[41] These depictions often blended fear with comedy, elevating venereal woes to allegories of societal ills.^[42] Visual art from the Renaissance era incorporated pox allusions to convey sin and suffering, particularly in depictions of diseased or grotesque figures. Hieronymus Bosch's paintings, such as The Garden of Earthly Delights (c. 1490–1500), feature tormented bodies with lesions and deformities suggestive of syphilitic ravages, symbolizing lust's hellish consequences amid the disease's spread across Europe post-Columbus.^[43] These motifs extended to satirical prints and panels, where pox-marked sinners embodied moral warnings, influencing later artists like Pieter Bruegel the Elder in evoking communal vice.^[44] In film, "pox" has inspired niche explorations of absurdity and alienation. The 2011 short film Pox, directed by Lisa Hammer, presents a surreal comedy fusing Charles Manson family lore with spy thriller elements, centering on a protagonist named Pox who navigates betrayal and spa escapism under the guidance of an invisible alien manager.^[45] This 20-minute work, expanded from a cable-access series, uses pox as a titular motif for personal and cosmic affliction, blending dark humor with anti-establishment satire.^[46]

Other uses

Pox (beverage)

Pox is a traditional Mexican spirit originating from the Chiapas region, where it holds deep cultural significance among the indigenous Tzotzil Maya people. The name "pox," pronounced "posh," derives from the Tzotzil Mayan language, meaning "medicine" or "healing," reflecting its historical use as a curative and spiritual elixir. Dating back to pre-Columbian times, pox has been employed in ceremonial rituals marking life events such as births, marriages, and deaths, serving as a communal offering to connect participants with the divine and foster social bonds.^[47]^[48]^[49] The production of pox involves fermenting and distilling a blend of corn—typically including white, yellow, red, and black varieties—along with sugarcane (often in the form of piloncillo) and malted wheat or wheat bran. The corn is nixtamalized, ground into masa, and mixed with the other ingredients before fermentation in wooden vats, followed by distillation in copper or clay stills, either once for a rustic profile or twice for a smoother finish. Minimal aging occurs, resulting in a clear, unaged spirit with an alcohol by volume (ABV) generally ranging from 40% to 50%, though variations exist based on the producer's methods.^[50]^[51]^[52] Varieties of pox include the plain, unadulterated version as well as flavored iterations infused with ingredients like coffee, chocolate, vanilla, or coconut, often at lower ABVs around 20% for digestif-style options. Notable brands such as Poshería, which offers an array of artisanal expressions including ancestral and flavored types, and Siglo Cero, founded in 2010 and the first to enter the U.S. market in 2017, have helped commercialize and diversify the spirit while preserving traditional techniques.^[47]^[53]^[54] In Chiapas, pox is traditionally consumed neat, poured into small clay cups (copitas) and paired with fresh fruit slices, such as orange, or roasted peanuts to complement its sweet, earthy notes reminiscent of corn and subtle malt. Its cultural role extends beyond rituals into daily life as a symbol of hospitality and resilience among Maya communities, with modern producers emphasizing sustainable practices tied to local agriculture. Since 2020, pox has gained international traction in craft cocktail scenes, appearing in bars across Mexico City, the U.S., and Europe, where mixologists highlight its versatility in drinks featuring citrus, coffee, or tropical elements.^[55]^[48]^[56]

Pox as exclamation and slang

The phrase "a pox on you" emerged in Elizabethan English as a potent curse invoking the suffering of pox diseases, often used to wish plague-like affliction upon an enemy.^[57] This exclamatory form appears in William Shakespeare's The Tempest (circa 1611), where the character Trinculo exclaims, "A pox o' your throat, you bawling, blasphemous, incharitable dog!" to express vehement disdain.^[58] By the 17th and 18th centuries, such curses drew on the era's familiarity with devastating pox outbreaks, blending epidemiological dread with rhetorical force, as seen in broader Tudor-era invectives.^[59] In slang usage, "the pox" historically referred to syphilis, a venereal disease notorious for its disfiguring pockmarks, particularly in 16th- to 18th-century Europe where it was euphemistically termed to avoid direct nomenclature.^[57] This colloquialism permeated literature and daily speech, reflecting the disease's social stigma and prevalence before effective treatments; for instance, it symbolized moral decay in 18th-century British cultural depictions.^[60] By the 19th century, "pox" had softened into a mild expletive or adjective like "poxy," denoting something inferior or contemptible, as in British vernacular for subpar quality.^[61] Modern informal uses include "chickenpox party," a pre-vaccine practice in the United States where parents deliberately exposed children to varicella to induce mild infection and confer immunity, popular until the 1995 vaccine introduction but now discouraged due to risks of severe complications.^[62] These linguistic remnants persist in literature and idioms, echoing pox's historical terror while diminishing in everyday curses following smallpox's global eradication in 1980, though exact usage trends remain anecdotal.

POX in technology

In computing, POX stands for Plain Old XML, a lightweight approach to web services that involves exchanging raw XML documents over HTTP without the SOAP envelope or additional WS-* standards.^[63] This method emphasizes simplicity and interoperability, serving as an alternative to the more complex SOAP-based protocols by focusing on basic HTTP messaging with XML payloads.^[64] POX gained prominence in the mid-2000s through frameworks like Windows Communication Foundation (WCF), where it enables direct XML communication for RPC-style services, reducing overhead in scenarios requiring minimal protocol layers.^[64] In materials science, POx refers to poly(2-oxazoline)s, a class of biocompatible polymers synthesized via cationic ring-opening polymerization of 2-oxazoline monomers, offering tunable hydrophilicity and low immunogenicity.^[65] These polymers have been explored since the 2010s for biomedical applications, particularly in drug delivery systems such as micelles and conjugates, where their amphiphilic nature allows encapsulation of hydrophobic therapeutics.^[65] A key property is their stealth coating capability, mimicking polyethylene glycol (PEG) by forming a hydrated brush-like layer on nanoparticles that evades immune recognition and extends circulation time in vivo.^[66] In software-defined networking (SDN), POX is a Python-based platform originally developed as an OpenFlow controller to manage network flows programmatically, decoupling control from data planes.^[67] Introduced in the early 2010s by the NOX team, it functions as a lightweight prototyping tool for SDN experiments, supporting modules for tasks like switching, firewalls, and load balancing via OpenFlow protocols.^[67] POX has been widely adopted in educational contexts, including Georgia Tech's SDN courses, due to its simplicity and ease of extension for testing network innovations without heavy dependencies.^[68]

References

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Pox - Gastro Obscura
Similar to Oaxacan mezcal, pox is sold in single-distilled, double-distilled, and flavored versions (coffee, coconut, chocolate, and vanilla). In Chiapas ...Missing: beverage | Show results with:beverage
[46]
What is Pox? The Mexican Spirit Explained - Cocktail Society
Sep 5, 2023 · The original producers are indigenous Tzotzil Mayans from the Mexican state of Chiapas. For them, the corn-spirit played a key role in religious ...Missing: beverage origins
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https://www.liquor.com/articles/mexican-drink-pox/
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https://www.tastingtable.com/1570529/mexico-oldest-spirit-pox-whiskey-fans/
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Meet Mexico's Oldest Spirit: Pox Is A Must-Try For Whiskey Fans ...
Apr 29, 2024 · Pox has been produced in Chiapas for generations and has become more prevalent in cocktail bars across Mexico in the past decade. In the United ...
[50]
What the Heck is Pox? Mexico's Most Mysterious Spirit, Explained
Pox hails from the highlands of Chiapas, in southern Mexico, where it has been distilled and sipped for centuries by the Tzotzil Maya people. This isn't just a ...Missing: etymology | Show results with:etymology
[51]
This Uncommon Mayan Spirit Is Making Its Way Behind Bay Area Bars
Aug 21, 2023 · Mayans, proud of their Zapatista history, weren't quick to share their liquor recipes with Siglo Cero. But by 2020 pox trickled into United ...
[52]
pox, n. meanings, etymology and more - Oxford English Dictionary
Any of several infectious diseases characterized by a rash of pustules (pocks), esp. smallpox, cowpox, and chickenpox.Missing: encyclopedia | Show results with:encyclopedia
[53]
pox, n. 1 - Green's Dictionary of Slang
Shakespeare Tempest I i: A pox o' your throat, you bawling ... 175: A pox on you! 1985, [Aus], J. Morrison Share House Blues 17: A pox on Mrs ...Missing: origin | Show results with:origin
[54]
The 1600s Were a Watershed for Swear Words | History Today
Aug 8, 2022 · For the latter, the Tudors would have substituted something diabolical – 'the devil rot thee' – or epidemiological – 'a pox on you'.
[55]
Itch, Clap, Pox - Yale University Press
In this book, literary critic Noelle Gallagher explores the cultural significance of the “clap” (gonorrhea), the “pox” (syphilis), and the “itch” (genital ...
[56]
49 British Swearwords, Defined - BuzzFeed
Feb 5, 2024 · 38. Poxy – adj., riddled with pox; crappy, third-rate. Mild. 39. Prat – n., idiot. Mild.
[57]
About Chickenpox - CDC
Apr 24, 2024 · Vaccinated people who get chickenpox may develop lesions that do not crust. These people are contagious until no new lesions have appeared for ...Chickenpox (Varicella) · Chickenpox Vaccine Saves... · SymptomsMissing: 1995 | Show results with:1995
[58]
Interoperability with POX applications - WCF - Microsoft Learn
Jul 23, 2022 · "Plain Old XML" (POX) applications communicate by exchanging raw HTTP messages that contain only XML application data that is not enclosed within a SOAP ...Missing: alternative | Show results with:alternative
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Basic HTTP Service - WCF - Microsoft Learn
Jul 29, 2022 · The BasicHttpService sample demonstrates how to implement an HTTP-based, RPC-based service - popularly referred to as "POX" (Plain Old XML) service.Missing: history | Show results with:history
[60]
Poly(2-oxazoline)s as polymer therapeutics - PubMed - NIH
Oct 15, 2012 · Poly(2-oxazoline)s (POx) are currently discussed as an upcoming polymer platform for biomaterials design and especially for polymer therapeutics.
[61]
Stealth Coating of Nanoparticles in Drug-Delivery Systems - PMC
Apr 20, 2020 · Poly(2-oxazoline) (POx) is a hydrophilic polymer that has been known for half a century [60]. It is highly tunable through living cationic ring- ...
[62]
noxrepo/pox: The POX network software platform - GitHub
POX is a networking software platform written in Python. POX started life as an OpenFlow controller, but can now also function as an OpenFlow switch.
[63]
When to Use Pox - Georgia Tech - Software Defined Networking
Feb 23, 2015 · Watch on Udacity: https://www.udacity.com/course/viewer#!/c-ud436/l-3616808815/m-438148614 Check out the full Computer Networking course for ...Missing: OpenFlow | Show results with:OpenFlow