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Synthetic element

A synthetic element is a that does not occur naturally on in significant amounts and is instead produced artificially through processes, such as bombarding atomic nuclei with particles in accelerators or reactors. The concept includes two lighter elements missing from nature due to radioactive instability— ( 43), the first synthetic element discovered in 1937 by Italian physicists Carlo Perrier and through deuteron irradiation of at the , Berkeley's , and ( 61), identified in 1945 by Jacob A. Marinsky, Lawrence E. Glendenin, and Charles D. Coryell via product analysis of and the only without stable isotopes. However, synthetic elements are predominantly the transuranic elements (atomic numbers 93–118), all of which are exclusively artificial, radioactive, and generated beyond (atomic number 92) in the periodic table; these include (93), (94), and up to (118), the heaviest known element approved in 2016. Produced by fusing heavy target nuclei (e.g., or ) with lighter projectiles like calcium ions in high-energy cyclotrons, these elements exhibit increasingly short half-lives—from plutonium-239's 24,110 years to oganesson's milliseconds—reflecting the limits of stability and the challenges of creating superheavy isotopes near the predicted "" around atomic numbers 114–126 with enhanced neutron counts. While most synthetic elements exist only fleetingly for scientific study of atomic properties and nuclear physics, some isotopes like technetium-99m (half-life 6 hours) enable over 80% of diagnostic nuclear medicine procedures worldwide, and plutonium-239 powers nuclear reactors and weapons.

Fundamentals

Definition

Synthetic elements are chemical elements that do not occur naturally on in significant amounts and are instead created artificially through nuclear reactions in laboratories. These elements are distinguished from elements, which consist of stable or long-lived isotopes that have persisted since the formation of the solar system and are found in significant quantities in the , oceans, and atmosphere. Unlike certain radioactive elements that appear in trace amounts due to ongoing natural processes such as or inclusion in and decay chains, synthetic elements lack stable isotopes and exhibit half-lives too short for primordial accumulation or significant natural production. All transuranic elements—those with atomic numbers greater than 92 ()—are synthetic, as they are not produced in stellar nucleosynthesis in sufficient quantities to exist naturally on . The only synthetic elements lighter than are (atomic number 43) and (atomic number 61), both of which have no stable isotopes and were first synthesized artificially despite their positions earlier in the periodic table. The International Union of Pure and Applied Chemistry (IUPAC), in collaboration with the International Union of Pure and (IUPAP), establishes criteria for confirming the synthesis of new elements through a joint working group that evaluates experimental data, ensures independent replication, and assigns discovery priority based on verifiable evidence. Upon confirmation, IUPAC oversees the naming process, requiring proposed names to derive from mythological concepts, minerals, places, properties, or scientists, with endings such as "-ium" for groups 1–16, "-ine" for group 17, and "-on" for group 18, followed by public review and approval.

Characteristics

Synthetic elements are highly radioactive due to their short half-lives, which span from microseconds for the heaviest isotopes to several years for some lighter transuranic ones, such as plutonium-244 with a half-life of about 80 million years, though most synthetic isotopes decay much more rapidly. This instability arises from the nuclear forces struggling to bind the large number of protons and neutrons, leading to prompt emission of alpha particles, beta particles, or fission fragments. For instance, superheavy elements like tennessine have isotopes with half-lives as short as 14 milliseconds, making their study reliant on detecting decay chains rather than isolating bulk samples. The atomic structure of synthetic elements shows increasing instability as atomic number rises beyond , primarily due to lowering fission barriers that favor spontaneous splitting of the over other modes. This trend is tempered by the island of stability hypothesis, which predicts enhanced for specific superheavy isotopes near proton numbers Z ≈ 114 or 120 and neutron numbers N ≈ 184, where closed shells could extend half-lives to seconds or even minutes, allowing potential chemical investigations. Current syntheses approach this region but have not yet reached isotopes with such prolonged . Chemically, transactinide elements (Z ≥ 104) largely follow periodic trends by resembling their lighter group analogs—for example, (Z=104) behaving akin to —but relativistic effects become prominent in superheavies, contracting s-orbitals and expanding d- and f-orbitals, which influences and . These effects, scaling with Z², can invert expected orbital energies and alter reactivity, such as stabilizing higher oxidation states or enhancing inertness in elements like . Nuclear properties of synthetic elements feature elevated neutron-to-proton ratios (often exceeding 1.5) to counterbalance electrostatic repulsion among protons, promoting relative in neutron-rich isotopes. Decay is predominantly via alpha emission, which reduces both proton and neutron counts while conserving mass-energy, though dominates in heavier cases (Z > 100), where the fragments into two medium-mass daughters plus s, bypassing stepwise alpha chains.

Production

Methods

Synthetic elements, particularly transuranic and ones, are primarily produced through reactions involving the bombardment of heavy nuclei with accelerated particles. The dominant method is fusion-evaporation, where a projectile collides with a nucleus to form a highly excited compound , which subsequently de-excites by evaporating neutrons (and occasionally charged particles) to yield the desired . This process requires overcoming the between the positively charged nuclei, typically achieved using particle accelerators to impart kinetic energies on the order of several MeV per . For early transuranic elements like , serves as a key method, where neutrons are absorbed by to form uranium-239, which undergoes to neptunium-239 and then to plutonium-239. However, for heavier synthetic elements beyond , charged-particle bombardments become essential, as cross-sections diminish rapidly with increasing . A representative example is the synthesis of (element 107), achieved via the reaction ^{209}\mathrm{Bi} + ^{54}\mathrm{Cr} \rightarrow ^{262}\mathrm{Bh} + 3n, where chromium-54 ions are accelerated onto a target, forming an excited compound nucleus that evaporates three neutrons. Two variants of fusion-evaporation are distinguished by the choice of and , affecting the of the compound nucleus: hot fusion and . Hot fusion employs lighter , such as , on (e.g., or ), resulting in higher around 40 MeV and evaporation of 3–5 neutrons, which facilitates access to neutron-richer isotopes but increases competition. Recent advances as of 2024 include the use of titanium-50 beams in hot fusion reactions, such as Ti-50 + Cm-248 to produce livermorium-116, demonstrating a pathway to neutron-richer isotopes for potential of elements beyond (Z=118). Ongoing experiments element 119 via reactions like Ti-50 + Bk-249 or V-51 + Cm-248, though cross-sections remain extremely low and no confirmed has occurred as of 2025. In contrast, uses heavier (e.g., zinc-70 or ) on near-doubly magic lead or , yielding lower of 10–15 MeV and typically 1-neutron evaporation, which enhances survival probability against but limits neutron richness. These approaches have been pivotal for elements 113–118 (hot fusion) and 107–112 (). An alternative method, multinucleon transfer (MNT), involves collisions between two heavy ions at energies near the , where multiple protons and neutrons are exchanged without complete , producing a distribution of neutron-rich or neutron-deficient fragments. Unlike fusion-evaporation, MNT does not form a single compound but generates diverse nuclides simultaneously, offering potential for synthesizing new isotopes in the superheavy region, though yields remain low due to quasielastic processes. Optimizing these reactions relies on measuring excitation functions, which plot the reaction cross-section (a measure of probability, often in picobarns or smaller) against the projectile's center-of-mass , revealing the energy window for maximum yield while minimizing competing channels like . Cross-sections for superheavy production are exceedingly small (e.g., 1–10 pb for elements around Z=114), necessitating extended irradiation times and sensitive detection, with theoretical models guiding the selection of projectile-target combinations to maximize probability.

Facilities and Techniques

The synthesis of synthetic elements, particularly ones, relies on specialized facilities capable of producing high-energy heavy-ion beams. Early efforts utilized s, such as the 60-inch at the , which enabled the initial production of transuranic elements like and in the . Modern facilities employ linear s and s for greater beam control and intensity, with recent upgrades enhancing capabilities as of 2025. For instance, the GSI Helmholtz Centre for Heavy Ion Research in , , operates the UNILAC linear and the SIS18 to accelerate s up to energies exceeding 10 MeV per , facilitating the creation of elements up to 112; the ongoing ( for and Research) upgrade aims to increase beam intensities for studies. Similarly, the (JINR) in , Russia, features the U400 and the DC280 superconducting complex, designed specifically for element synthesis with beams like on actinide targets, delivering up to 0.3 particle-μA. In , RIKEN's Nishina Center for -Based has upgraded its facilities, including a new , to lead attempts at synthesizing element 119 using reactions like Cr-50 + Eb-249, with experiments ongoing as of January 2025. Additionally, the CAFE () at the Institute of Modern Physics in , , has produced new isotopes, such as seaborgium-257 in 2025, expanding production in the region. Detection of the fleeting synthetic nuclei produced in these reactions requires sophisticated separation and identification techniques due to their low production cross-sections, often on the order of picobarns. Gas-filled recoil separators, such as the SHIP (Separator for Heavy Ion Reaction Products) at GSI and the DGFRS ( Gas-Filled Recoil Separator) at JINR, exploit the of fusion-evaporation reactions to isolate heavy s from the primary beam and scattered particles, achieving separation efficiencies above 50% for superheavy elements. These separators direct recoils to focal-plane detectors, typically arrays of strip detectors that measure alpha-particle energies, decay chains, and events with resolutions better than 20 keV. Chemical separation methods complement physical techniques, particularly for transactinides, by exploiting differences in gas-phase to confirm elemental identities, as demonstrated in studies of elements like . Target materials are crucial for maximizing probabilities and are typically thin foils of enriched isotopes, such as 244Pu or 248Cm, produced in high-flux reactors and electroplated to thicknesses of 0.3–1 mg/cm² to minimize energy loss. Beam intensities have escalated dramatically in contemporary setups, with facilities like JINR delivering 48Ca beams at up to 0.3 particle-μA (equivalent to 1.8 × 10^13 ions per second) to compensate for minuscule cross-sections and enable statistically significant event counts over months-long irradiations. enhances efficiency in these resource-intensive experiments, including robotic target changers at GSI and JINR to rotate or replace foils without interrupting beam delivery, reducing downtime and . International collaborations underpin the verification of synthetic element discoveries, with joint experiments across facilities like GSI, JINR, , and emerging centers in ensuring reproducibility. The International Union of Pure and Applied Chemistry (IUPAC) and International Union of Pure and Applied Physics (IUPAP) convene Joint Working Parties to rigorously evaluate claims, requiring independent confirmation of decay chains and cross-sections before official recognition.

History

Early Syntheses

The early syntheses of synthetic elements occurred in the context of burgeoning in the 1930s and 1940s, a period marked by rapid advancements in particle accelerators and the exploration of artificial radioactivity following the discoveries of Irene and Frédéric Joliot-Curie in 1934. Researchers sought to fill gaps in the periodic table, particularly for elements predicted but not observed in nature due to their inherent instability and short half-lives, which prevented significant natural accumulation over Earth's 4.5-billion-year history. These efforts were driven by cyclotrons and nuclear reactions, enabling the production of previously unknown isotopes. The first synthetic element, ( 43), was produced in 1937 by Italian physicists Carlo Perrier and at the . Segrè, who had collaborated with O. Lawrence at the , received a molybdenum foil used as a deflector in Lawrence's , which had been bombarded with deuterons ( nuclei) during operation. Perrier and Segrè chemically separated trace amounts of new radioactive isotopes from the irradiated foil, identifying them through their decay properties and chemical behavior, which matched predictions for the missing element between and . They verified its identity by showing it formed insoluble perrhenates similar to and exhibited no natural occurrence, attributing its absence to the longest-lived isotope's of approximately 4.2 million years for ^{98}Tc, too brief for survival. Initially referred to as "element 43," it was named in 1947 by IUPAC, from the Greek technetos meaning "artificial," reflecting its solely synthetic origin. Promethium (atomic number 61), the second early synthetic element, was discovered in 1945 amid nuclear research at in , though not publicly announced until 1947 due to wartime secrecy. Jacob A. Marinsky, Lawrence E. Glendenin, and Charles D. Coryell isolated it from the fission products of irradiated in a , using ion-exchange chromatography to separate rare earth elements and identifying (half-life 2.62 years) through its and chemical properties akin to other lanthanides. To confirm its existence, they synthetically produced it via neutron bombardment of neodymium-146, yielding and verifying the ion-exchange fractions' purity. Like , 's absence in nature stems from instability, with its longest-lived isotope ^{145}Pm having a of 17.7 years, insufficient for detectable terrestrial amounts beyond trace fission byproducts. The team proposed the name in 1949, drawing from the mythological who stole fire from the gods, symbolizing humanity's creation of this elusive element.

Transuranic Era

The Transuranic Era marked a pivotal phase in the synthesis of elements beyond , beginning with the discovery of (element 93) in 1940 through the bombardment of with neutrons at the , by and Philip H. Abelson. This breakthrough was followed closely by the identification of (element 94) in 1941, when , along with McMillan, , and Arthur C. Wahl, chemically separated and confirmed the new element produced via deuteron bombardment of uranium in the Berkeley . These initial syntheses laid the groundwork for exploring the actinide series, demonstrating that heavier elements could be created artificially in particle accelerators. The , initiated in response to imperatives, accelerated transuranic research by integrating these discoveries into efforts to produce fissile materials for nuclear weapons. production scaled up dramatically using nuclear reactors, such as those at the , where on in graphite-moderated piles yielded kilogram quantities of essential for the atomic bomb. Post-war, this infrastructure enabled further advancements; in 1944, Seaborg's team at the in synthesized (element 95) and (element 96) by bombarding with neutrons and alpha particles, respectively, marking the first deliberate creation of elements beyond . By 1949 and 1950, (97) and (98) were produced at through helium-ion bombardment of and , respectively, highlighting the evolving use of cyclotrons for transuranic generation. The era's later discoveries included einsteinium (99) and fermium (100), identified in 1952 from coral debris collected after the Ivy Mike thermonuclear test in the Pacific, where intense neutron fluxes in the explosion's uranium tamper produced these elements via successive captures; due to classification, results were declassified and published in 1955. Mendelevium (101) followed in 1955 at Berkeley, synthesized by alpha-particle bombardment of einsteinium in the 60-inch cyclotron, representing the first identification of a transuranic element on an atom-by-atom basis. Nobelium (102) was confirmed in 1958 by Albert Ghiorso's Berkeley team through helium-ion irradiation of curium, amid competing claims. Lawrencium (103), the era's capstone, was created in 1961 at Berkeley via boron-ion bombardment of californium, closing the initial actinide series. Throughout this period, naming controversies underscored the competitive fervor of the , particularly between U.S. and Soviet scientists. For , the 1957 claim by the Nobel Institute in led to the name's adoption, despite Berkeley's 1958 verification and Soviet assertions of prior discovery in ; the International Union of Pure and Applied Chemistry (IUPAC) upheld "nobelium" in 1992 amid ongoing disputes. Similar rivalries emerged, with Soviet teams at the claiming syntheses like element 102, fueling a broader race that mirrored geopolitical tensions and prompted accelerated U.S. investments in accelerators like the Berkeley Heavy-Ion Linear Accelerator. These efforts not only expanded the periodic table but also advanced techniques central to the era.

Superheavy Advances

The synthesis of superheavy elements began with element 104, rutherfordium, amid intense international competition. In 1964, scientists at the Joint Institute for Nuclear Research (JINR) in Dubna, Russia, reported the production of element 104 through the bombardment of plutonium-242 with neon-22 ions, though confirmation was debated due to limited evidence. Independently, researchers at Lawrence Berkeley National Laboratory (LBNL) in the United States claimed discovery in 1969 using californium-249 bombarded with carbon-12, leading to a prolonged dispute resolved by the International Union of Pure and Applied Chemistry (IUPAC) in favor of shared credit for both teams. This rivalry extended to element 105, dubnium, with Dubna announcing synthesis in 1968 via plutonium-242 and nitrogen-15, while Berkeley reported it in 1970 using americium-243 and neon-22, again resulting in joint recognition after IUPAC arbitration. These early clashes highlighted the challenges of verifying fleeting superheavy nuclei and set the stage for collaborative yet competitive efforts in the field. The in played a pivotal role in advancing the synthesis of elements 106 through 118, leveraging hot fusion techniques with beams on targets. Element 106, , was first reported by the team in 1974 through the reaction of lead-208 with chromium-54, marking a significant step in extending the periodic table despite initial naming disputes with . This approach culminated in the discovery of (element 118) in 2006, produced by fusing californium-249 with in a reaction yielding a single atom of oganesson-294 with a cross-section of approximately 0.5 picobarns: ^{249}\mathrm{Cf} + ^{48}\mathrm{Ca} \rightarrow ^{294}\mathrm{Og} + 3n. 's contributions, often in collaboration with LBNL and other international partners, filled the seventh row of the periodic table, demonstrating the efficacy of gas-filled recoil separators for detecting these ultra-short-lived isotopes with half-lives on the order of milliseconds. Theoretical predictions of an "" posit that superheavy elements around atomic numbers 114 to 126, with specific numbers near 184, could exhibit enhanced stability due to closed nuclear shells, potentially extending half-lives to seconds or longer compared to the microseconds typical of known superheavies. Efforts to reach elements 119 and beyond have intensified since 2019, with past experiments at GSI Helmholtz Centre for Heavy Ion Research in , , attempting titanium-50 on berkelium-249, and ongoing attempts at in using vanadium-51 on curium-248 since 2018, but no confirmed syntheses have occurred as of November 2025 due to minuscule cross-sections below 1 picobarn and detection challenges. These attempts probe the predicted shoreline of the island, where isotopes like element-120 with 184 s might achieve greater resistance, though current facilities require upgrades for sufficient beam intensity. In 2024, a breakthrough in superheavy production enhanced yields for ( 116), using titanium-50 beams accelerated at LBNL's 88-Inch to bombard targets, successfully creating two atoms of livermorium-290 with a cross-section of 0.44 picobarns—nearly double that of the traditional method. This titanium-based approach, developed through innovative techniques like the Versatile ECR for Nuclear Science (), offers a pathway to heavier elements by enabling reactions with more neutron-rich projectiles, potentially aiding quests for elements 119 and 120.

Catalog

List

The synthetic elements are cataloged below in a table listing their , , name, year of (based on IUPAC-recognized ), primary discoverers, and location of . Elements 43 and 61 are synthetic despite being below 93, as they do not occur naturally in significant quantities. For elements 113–118, temporary systematic names (e.g., ununtrium for 113, ununpentium for 115) were used prior to official naming by IUPAC, following the convention of Latin roots for atomic numbers (e.g., "un-un" for 1-1, "pent" for 5).
Atomic NumberSymbolNameDiscovery YearDiscoverersLocation
43TcTechnetium1937Carlo Perrier, Emilio G. SegrèUniversity of Palermo, Italy
61PmPromethium1945Jacob A. Marinsky, Lawrence E. Glendenin, Charles D. CoryellOak Ridge National Laboratory, USA
93NpNeptunium1940Edwin M. McMillan, Philip H. AbelsonUniversity of California, Berkeley, USA
94PuPlutonium1940Glenn T. Seaborg, Edwin M. McMillan, Joseph W. Kennedy, Arthur C. WahlUniversity of California, Berkeley, USA
95AmAmericium1944Glenn T. Seaborg, Ralph A. James, Leon O. Morgan, Albert GhiorsoMetallurgical Laboratory, University of Chicago, USA
96CmCurium1944Glenn T. Seaborg, Ralph A. James, O. M. Stewart Jr., Albert GhiorsoUniversity of California, Berkeley, USA
97BkBerkelium1949Stanley G. Thompson, Glenn T. Seaborg, Kenneth Street Jr., Albert GhiorsoUniversity of California, Berkeley, USA
98CfCalifornium1950Stanley G. Thompson, Kenneth Street Jr., Albert Ghiorso, Glenn T. SeaborgUniversity of California, Berkeley, USA
99EsEinsteinium1952Albert Ghiorso, Stanley G. Thompson, Glenn T. Seaborg et al.University of California, Berkeley, USA (from thermonuclear debris)
100FmFermium1952Albert Ghiorso, Stanley G. Thompson, Glenn T. Seaborg et al.University of California, Berkeley, USA
101MdMendelevium1955Albert Ghiorso, Glenn T. Seaborg, Stanley G. Thompson et al.University of California, Berkeley, USA
102NoNobelium1966Georgy Flerov et al. (JINR team)Joint Institute for Nuclear Research (JINR), Dubna, Russia
103LrLawrencium1961Albert Ghiorso, Torbjørn Sikkeland, John R. Walton, Glenn T. SeaborgUniversity of California, Berkeley, USA
104RfRutherfordium1969Albert Ghiorso et al. (Berkeley team); joint credit with G. N. Flerov et al. (Dubna team, 1964 claim)University of California, Berkeley, USA (joint with JINR, Dubna, Russia)
105DbDubnium1970Albert Ghiorso et al. (Berkeley team); joint credit with G. N. Flerov et al. (Dubna team)University of California, Berkeley, USA (joint with JINR, Dubna, Russia)
106SgSeaborgium1974Albert Ghiorso, Glenn T. Seaborg et al.University of California, Berkeley, USA
107BhBohrium1981G. Münzenberg, P. Armbruster et al.GSI Helmholtz Centre, Darmstadt, Germany
108HsHassium1984G. Münzenberg, P. Armbruster et al.GSI Helmholtz Centre, Darmstadt, Germany
109MtMeitnerium1982G. Münzenberg, P. Armbruster et al.GSI Helmholtz Centre, Darmstadt, Germany
110DsDarmstadtium1994S. Hofmann, V. Ninov et al.GSI Helmholtz Centre, Darmstadt, Germany
111RgRoentgenium1994S. Hofmann, V. Ninov et al.GSI Helmholtz Centre, Darmstadt, Germany
112CnCopernicium1996S. Hofmann, V. Ninov et al.GSI Helmholtz Centre, Darmstadt, Germany
113NhNihonium2004K. Morita et al. (RIKEN team)RIKEN, Wako, Japan
114FlFlerovium1999Yuri Oganessian et al. (JINR team)JINR, Dubna, Russia
115McMoscovium2003Yuri Oganessian et al. (JINR, with LLNL collaboration)JINR, Dubna, Russia (joint with Lawrence Livermore National Laboratory, USA)
116LvLivermorium2000Yuri Oganessian et al. (JINR, with LLNL collaboration)JINR, Dubna, Russia (joint with Lawrence Livermore National Laboratory, USA)
117TsTennessine2010Yuri Oganessian et al. (JINR, LLNL, ORNL, Vanderbilt University collaboration)JINR, Dubna, Russia (joint with USA institutions)
118OgOganesson2002Yuri Oganessian et al. (JINR, with LLNL collaboration)JINR, Dubna, Russia (joint with Lawrence Livermore National Laboratory, USA)

Stability and Isotopes

(Z=43) and (Z=61) are synthetic elements below the transuranic range due to the absence of stable and negligible natural abundance. The longest-lived technetium isotope is ^{98}Tc, with a of 4.2 million years, decaying primarily by emission to stable ^{98}Ru. For , ^{145}Pm has the longest of 17.7 years, decaying by to stable ^{145}Nd. Transuranic synthetic elements (atomic numbers greater than ) exhibit nuclear instability due to the imbalance between the and electrostatic repulsion among protons, leading to . Their isotopes have half-lives spanning a vast range, from fractions of a for superheavy nuclides to tens of millions of years for certain actinides, reflecting the increasing instability with higher atomic number (Z). The primary decay modes for synthetic element isotopes are alpha decay, which reduces both Z and mass number by 2, and spontaneous fission, where the nucleus splits into two lighter fragments, prevalent in heavier isotopes due to shell effects and fission barriers. Beta decay occurs less frequently in these neutron-rich or neutron-deficient nuclides, as the odd-even nucleon pairing influences stability; even-even isotopes tend to favor alpha or fission over beta processes. Trends show that half-lives generally decrease as Z increases beyond 96, with spontaneous fission dominating for Z > 100 due to lower fission barriers, while alpha decay remains significant across the series; neutron number (N) near magic values (e.g., N=152 or 184) can enhance stability by increasing binding energy.
ElementIsotopeHalf-LifePrimary Decay Mode
Neptunium^{237}Np2.144 × 10^6 yearsα decay
Plutonium^{239}Pu24,110 yearsα decay (89.0%), spontaneous fission (0.00011%)
Plutonium^{244}Pu8.08 × 10^7 yearsα decay (99.88%), spontaneous fission (0.12%)
Curium^{247}Cm1.56 × 10^7 yearsα decay
Flerovium^{289}Fl1.9 sα decay
Oganesson^{294}Og0.7 msα decay
Among synthetic isotopes, the longest-lived include with a of 80.8 million years and curium-247 at 15.6 million years, both decaying predominantly via alpha emission to stable or longer-lived daughters; these durations allow trace natural occurrences in material, though most synthetic isotopes decay rapidly, limiting practical handling. Theoretical models predict an "" for elements around Z = 114–126 and N ≈ 184, where closed nuclear shells could raise barriers and extend half-lives to seconds, minutes, or even years, potentially enabling chemical studies of these elusive nuclides beyond current microseconds-scale observations.

Non-Synthetic Elements via Synthesis

Non-synthetic elements are those that occur naturally on , possessing stable isotopes in the environment, but certain isotopes of these elements are produced artificially in significant quantities due to their scarcity or specific industrial demands. Unlike fully synthetic elements, which do not exist in nature, these isotopes supplement or exceed natural abundances to meet practical needs, such as production or scientific research. Deuterium, a stable of comprising about 0.0156% of , is enriched artificially through processes like the Girdler-Sulfide method or to produce (D₂O) for use as a in nuclear reactors. This enrichment is driven by the need for in CANDU-type reactors, which utilize fuel, as deuterium's lower neutron absorption cross-section compared to ordinary enhances efficiency. Tritium, a radioactive with a 12.3-year , occurs only in trace amounts naturally from interactions but is primarily generated in nuclear reactors via on lithium-6 or , yielding quantities for research and weapons applications. Carbon-14, a beta-emitting with a 5,730-year , is produced cosmogenically in the atmosphere but supplemented artificially in reactors through irradiation of nitrogen-14 or , particularly for standards and biomedical tracers. , a rare in Earth's atmosphere (about 0.000137% of natural helium), is obtained mainly as a of artificially produced stored in facilities, with the U.S. Department of Energy extracting it during tritium replenishment for uses in and potential fusion fuels. These artificial productions address scarcities—such as tritium's fleeting natural presence or helium-3's low terrestrial concentration—while supporting industrial applications like moderation and research, distinguishing them from elements without any natural stable counterparts.

Applications

Synthetic elements and their isotopes find applications in production, , research, and , leveraging their radioactive properties for specific functions. serves as a primary in reactors for generation and as the core component in weapons due to its ability to sustain a . is widely incorporated into ionization smoke detectors, where it ionizes air to detect smoke particles through changes in electrical conductivity. In , is the most commonly used radioisotope for diagnostic imaging, such as in (SPECT) scans, owing to its 140 keV gamma emission and six-hour that allows sufficient time for procedures while minimizing patient radiation exposure. Certain isotopes, including curium-244 and curium-245, have been explored in betavoltaic nuclear batteries to power cardiac pacemakers, providing long-term energy through in compact devices. For research purposes, californium-252 acts as a portable neutron source in applications like prompt gamma neutron activation analysis (PGNAA) for material characterization, neutron radiography, nuclear waste assays, and reactor startups, thanks to its high neutron emission rate of about 2.3 × 10^6 neutrons per second per microgram. Superheavy elements, such as those beyond uranium, are synthesized primarily to probe and validate theories of nuclear structure, including shell effects and stability trends, as seen in studies of charge radii in fermium isotopes that confirm predictions of increased nuclear stability near magic numbers. Their short-lived nature limits practical uses but enhances understanding of atomic theory. The production and application of synthetic elements raise environmental and ethical concerns, including the generation of long-lived that requires secure disposal to prevent environmental contamination, as minor actinides like and contribute significantly to the radiotoxicity of nuclear waste over millennia. Additionally, international non-proliferation treaties, such as the Treaty on the Non-Proliferation of Nuclear Weapons (NPT), impose strict controls on and related materials to prevent their diversion for weapons purposes, emphasizing safeguards and obligations. Usability in these applications often hinges on the relative stability of isotopes, as detailed in analyses of synthetic element catalogs.

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