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Talc


Talc is a hydrous magnesium silicate mineral with the chemical formula Mg₃Si₄O₁₀(OH)₂, consisting primarily of magnesium oxide (MgO), silicon dioxide (SiO₂), and water. It occurs as foliated, fibrous, or massive crystalline masses and is the softest known mineral, ranking 1 on the Mohs hardness scale. Talc forms through the hydrothermal alteration or metamorphism of ultramafic rocks rich in magnesium, and major deposits are found in regions such as the United States, China, and India.
Due to its chemical inertness, high thermal stability, low electrical , and , talc serves as a versatile filler and extender in numerous applications, including ceramics, paints, plastics, rubber, production, and roofing materials. In cosmetics and pharmaceuticals, purified talc is employed as a , , and absorbent in products like powders and tablets, prized for its fine and non-reactivity. , an impure massive variety, is carved into sculptures and used in architectural elements for its heat resistance. Talc has faced scrutiny over potential health risks, particularly from perineal application of cosmetic talc, which some epidemiological studies associate with a modest increased risk of , potentially due to particle migration or historical asbestos contamination in certain deposits. However, meta-analyses and critical reviews highlight limitations such as in case-control studies and lack of consistent causation for asbestos-free talc, with no definitive mechanistic evidence linking pure talc to . Regulatory bodies like the FDA require testing for in talc products, as contaminated talc can pose inhalation risks akin to asbestos, though modern purified sources show negligible levels.

Chemical and Physical Properties

Composition and Structure

Talc is a hydrous with the ideal Mg₃Si₄O₁₀(OH)₂. This composition consists of 63.6% SiO₂, 31.9% MgO (as Mg), and 4.8% H₂O by weight in pure form. Talc exhibits a trioctahedral structure within the (sheet ) group, featuring alternating layers of tetrahedral silica sheets and octahedral sheets. The tetrahedral sheets comprise SiO₄ units linked in a hexagonal pattern, while the central octahedral layer has magnesium ions octahedrally coordinated by oxygen and hydroxyl groups. The individual 2:1 layers in talc are stacked and held together primarily by weak van der Waals forces rather than strong ionic or covalent bonds, resulting in perfect basal and a platy . Substitutions within the , such as Fe²⁺ or Al³⁺ replacing Mg²⁺ in octahedral sites or Al³⁺ substituting for Si⁴⁺ in tetrahedral sites, introduce minor compositional variations that can alter color from white to gray or green. Associated impurities in natural deposits often include carbonates like or , silicates such as or , and , which affect overall purity and are deposit-specific. Talc is distinguished from similar phyllosilicates by its magnesium-dominated trioctahedral occupancy; , for instance, is dioctahedral with Al₂Si₄O₁₀(OH)₂, lacking magnesium in the octahedral sheet. , another sheet silicate, incorporates an additional interlayer of brucite-like (Mg,Fe)(OH)₂ sheets between the 2:1 talc-like layers, yielding a formula approximating (Mg,Fe,Al)₆(AlSi₃)O₁₀(OH)₈. These structural and compositional differences underpin distinct mineral behaviors, though impure deposits may require analytical methods like for accurate identification.

Physical Characteristics and Mohs Scale

Talc exhibits a Mohs hardness of 1, defining it as the softest mineral and the standard reference for the lowest point on the scale. This exceptional softness arises from its layered silicate structure, featuring weak interlayer bonds that allow easy deformation and scratching by a fingernail. The mineral displays a characteristic greasy feel when handled, resulting from the sliding of its fine, platy particles against the skin. In terms of luster, talc shows a pearly to greasy appearance, often translucent in thin sheets. It possesses perfect along the {001} basal , enabling it to split into flexible, thin laminae without brittle . Color variations typically range from to pale green or grayish hues, influenced by minor impurities, with a streak. The of talc falls between 2.7 and 2.8 g/cm³, reflecting its relatively low mass due to the predominance of elements in its composition. These physical traits, including the platy and interlayer weakness, confer poor and electrical , positioning talc as an effective in bulk form. Such properties underpin its industrial value as a and filler, where minimal and reinforcement without added hardness are desired.

Etymology and History

Etymology

The word talc derives from the ṭalq (طَلْق), originally referring to or a similar flaky , due to the shared schistose and appearance of early specimens. This term traces further to the talk or tālk, possibly denoting a medicament or pure substance, which facilitated its transmission through trade routes. By the , the word entered European languages via talcum or talcus, as documented in mineralogical texts, where it initially encompassed various lightweight, lamellar minerals before being narrowed to the specific hydrous magnesium Mg₃Si₄O₁₀(OH)₂. formalized its usage in 1564, distinguishing talc from amid growing systematic classification efforts in . The English adoption occurred around , aligning with the term's refinement to exclude broader connotations of purity or unrelated phyllosilicates.

Historical Discovery and Early Uses

Talc, primarily recognized in its massive form as , was utilized in for carving vessels, tools, and ornaments due to its softness and workability. Archaeological evidence from indicates quarrying for cooking pots and household items dating back to the period, with production continuing through the for jewelry and structural elements like stove linings. Similarly, prehistoric sites in reveal Native American use of for bowls, cooking vessels, and shaft straighteners, exploiting its thermal stability to retain heat without cracking. In ancient Mediterranean civilizations, soapstone's properties enabled fine carvings, such as scarab amulets by Egyptians and stamps by Cretans around 2000 BCE, demonstrating early appreciation for its carvability and polishability. These applications underscored talc's empirical value in durable, heat-resistant artifacts suitable for daily and ritual use. The scientific identification of talc advanced in the late 18th century amid the development of crystallography, with René-Just Haüy's 1784 observations on crystal geometry laying groundwork for systematic mineral classification, including talc's recognition as a distinct phyllosilicate by the early 19th century. Early European mining focused on high-quality deposits, such as Norway's prehistoric quarries yielding steatite blocks and Italy's Pinerolo region, exploited since medieval times for pure talc in cosmetics and pigments due to its inertness and fineness. Pre-20th century uses extended to , where talc-rich allowed intricate detailing in European and Asian artworks, and to rudimentary ceramics, incorporating ground talc for enhanced whiteness and in glazes and bodies, providing practical durability without modern scaling. These applications highlighted talc's utility in contexts demanding resistance to wear and heat, predating industrial refinement.

Geological Formation and Occurrence

Geological Formation Processes

Talc forms predominantly through metamorphic alteration of magnesium-rich s, such as ultramafic rocks, , and serpentinites, under low-grade conditions involving silica introduction via fluids. Regional drives this process by subjecting these rocks to temperatures of approximately 200–400°C and pressures up to 2 kbar, facilitating reactions like + → talc + + CO₂ in the CaO–MgO–SiO₂–CO₂–H₂O system. Field observations in metamorphic belts reveal talc in foliated assemblages with or , confirming transformation without melting, while phase equilibria modeling supports stability in . Hydrothermal processes contribute significantly, particularly through metasomatic exchange where hot, silica-bearing fluids (often meteoric or magmatic brines) interact with magnesium-enriched hosts like s. In serpentinized peridotites, silica replaces or with talc at temperatures below 550°C and elevated CO₂ partial pressures, producing replacement textures observed petrographically. Magnesium occurs less frequently, as in cases of Mg loss from enriching adjacent silica sources, but empirical stable isotope data (e.g., Mg ) trace fluid pathways linking alteration to slab or seafloor processes. hydrothermal experiments replicate these reactions, demonstrating talc nucleation via dissolution-reprecipitation under controlled P-T-fluid conditions. Igneous-related talc formation is uncommon, typically limited to contact near intrusions or late-stage hydrothermal veins in pegmatites, where magmatic fluids provide silica but do not dominate global deposits. Validation across pathways relies on empirical proxies like mineral zoning, fluid inclusion thermometry (yielding 350–500°C for some acicular varieties), and experimental , underscoring causal fluid-rock ratios and metasomatic gradients over speculative models.

Global Occurrence and Major Deposits

Talc deposits are distributed worldwide, occurring primarily in metamorphic terrains within orogenic belts and associated with ultramafic rocks such as and . These include major concentrations in the of the , extending from southward to , as well as in the region. In , significant deposits are found in the belt, spanning countries like , , , and , where talc lenses form within folded metamorphic sequences. The in host similar deposits in belts, reflecting orogenic activity. In , talc is abundant in complexes and metamorphic zones, particularly in and . 's Province features the Haicheng deposit, one of the largest known talc occurrences, characterized by exceptionally pure, massive talc bodies within altered ultramafics. Indian deposits align with Himalayan ophiolites and associated metamorphic belts, though often intermingled with phyllites. Tectonic settings in these regions, including subduction-related , contribute to variations in deposit purity, with and massive forms generally yielding higher-grade material compared to schistose varieties embedded in foliated host rocks. Other notable regions encompass Brazil's state, where deposits occur in shields, and Australia's , including the Three Springs area with large soapstone-type talc. Globally, talc resources are substantial, with identified reserves estimated to support long-term abundance, as world resources approximate five times the current reserve base according to U.S. Geological Survey assessments. Accessibility is influenced by the structural integrity of host formations, with purer deposits often in less deformed massive lenses versus disseminated schistose occurrences.

Mining, Production, and Economics

Mining Methods and Challenges

Talc is predominantly mined using open-pit methods, which are well-suited to its soft, friable deposits typically found near the surface, allowing for efficient extraction without extensive underground operations. Selective mining practices, including careful ore zone delineation and hand sorting, are applied to segregate high-quality talc from associated impurities such as minerals and asbestos-bearing amphiboles like , thereby minimizing contamination in the feedstock. Post-extraction, beneficiation begins with primary and secondary crushing to break down the , followed by screening to classify particles by size. Flotation processes exploit talc's inherent hydrophobicity to float and separate it from hydrophilic , often enhanced by collectors and frothers for optimal recovery. The concentrate is then dried and subjected to dry grinding or to achieve fine particle sizes, yielding industrial-grade talc with purity levels typically exceeding 95%. Operational challenges include managing respirable generated during , crushing, and grinding, which is mitigated through sprays, enclosed systems, and to protect workers and reduce airborne emissions. consumption arises primarily from flotation circuits and dust suppression, requiring strategies to address scarcity in arid regions, though talc's low reduces overall compared to or metallic ores. Complete avoidance of remains difficult due to geological intergrowths with tremolite-actinolite series minerals, demanding vigilant deposit and multi-stage purification to meet thresholds. Despite these hurdles, talc exhibits a relatively low , involving minimal blasting and rapid site rehabilitation potential owing to the absence of risks.

Global Production Statistics and Trade

Global talc production reached approximately 8 million metric tons in 2024, with projections indicating growth to 8.07 million tons in 2025. dominated output at 1.8 million metric tons in 2023, accounting for roughly 40-50% of the total, followed by at 1.0 million metric tons and at 0.85 million metric tons. Other notable producers included the , , and , though their shares were smaller. In the United States, three companies operated five talc mines across three states in , with total sales estimated at 510,000 tons in the subsequent year. Key domestic production occurred in and , contributing to an output of around 0.5-1 million tons annually. The global market value stood at approximately USD 2.9 billion in , reflecting demand in sectors such as plastics, , and . Industry growth has sustained a (CAGR) of 3.5-4.35% in recent years, driven primarily by expanding applications in polymer composites and . Trade patterns feature significant exports from —led by and —to and , with the also exporting USD 133 million worth in 2021. Supply chains demonstrated resilience following disruptions, supported by diversified sourcing and stabilized operations.
Top Producers (2023, million metric tons)Output
1.8
1.0
0.85
~0.5

Conflict-Associated Mining

In , , talc mining operations in districts such as Achin, Khogyani, Sherzad, Momand Valley, and Ghunday have been under the control of the and (ISKP) since mid-2015, with the groups imposing taxes equivalent to approximately 20% of production value on miners and transporters. The has derived millions of dollars annually from these activities, including an estimated $22 million province-wide in 2014 and $2.2 million to $10.5 million yearly based on output of around 500,000 tons valued at $60 per ton, while ISKP has generated tens of thousands to low millions through similar levies, such as $17,000 from taxing 300 trucks in January 2017 alone. These revenues, extracted via daily fees (Rs500,000–Rs1.2 million from specific Ghunday mines) and per-truck charges (Rs50,000–Rs100,000 for 40–60 ton loads), directly support insurgent operations and have persisted amid ongoing clashes between the groups for mine dominance as recently as . Extraction occurs with minimal government oversight in these remote, unstable areas, enabling unregulated smuggling networks that bypass formal licensing and export bans, such as the 2015 restriction that led to stockpiles exceeding 750,000 tons valued at $40 million. Primary export routes involve trucking talc through the border to Pakistan's region, where it is processed and re-exported—Afghanistan sent 561,286 tons to Pakistan in 2016, much of which reached and international markets thereafter. Following the Taliban's 2021 takeover, royalties on talc were increased threefold under their administration, further entrenching armed group influence over the sector despite nominal state control. This contrasts with mining in regulated operations, which comply with transparency mechanisms like those of the to mitigate illicit flows. Afghanistan's talc production, estimated at hundreds of thousands of tons annually from illicit sources, accounts for less than 5% of global output, which totals several million tons dominated by producers like and , thereby confining the geopolitical risks to a minor fraction of worldwide supply chains. Nonetheless, the opacity of these operations highlights vulnerabilities in global talc sourcing, where is essential to trace origins and prevent inadvertent revenue streams to non-state armed actors.

Applications and Uses

Industrial Applications

Talc functions as a reinforcing filler in plastics, enhancing , dimensional , , and tensile strength, which supports its application in automotive components and housings. In the United States, plastics represented 32% of talc consumption in 2024, reflecting its role in cost-effective reinforcement without compromising material integrity. In rubber manufacturing, talc serves as a and anti-stick , comprising 6% of U.S. that year, aiding and surface in tires and . Its platy particle structure and chemical inertness enable uniform dispersion, reducing and improving flow during . Talc is incorporated as a filler in production to boost opacity, whiteness, and smoothness, accounting for 9% of U.S. talc use in ; fine particle sizes ensure even coating distribution for enhanced printability. In paints and coatings, talc acts as an anti-settling agent and extender, representing 18% of consumption, leveraging its whiteness and inertness to maintain suspension and provide durable finishes. Ceramics employ talc for enhancement and fluxing, at 21% of U.S. use, where its uniform minimizes shrinkage variability across firing temperatures, optimizing and sanitaryware production. Across these sectors, talc's high whiteness, , and tunable distributions—achieved through milling—facilitate partial substitution of pricier resins or pigments, yielding empirical cost savings of up to 20-30% in formulations while preserving mechanical .

Consumer and Personal Care Uses

Talc serves as a key ingredient in various and due to its moisture-absorbing, opacity-enhancing, and texture-smoothing properties. In body powders and baby powders, it is applied to absorb excess moisture, reduce friction, and help prevent irritation such as diaper in infants. These applications rely on finely milled cosmetic-grade talc, which must meet stringent purity standards, including being asbestos-free and low in , as verified through processes like diffraction and . In makeup formulations, talc functions as a bulking agent and absorbent in products like eyeshadows, blushes, and , providing a smooth, adherent finish and preventing caking. Food-grade talc, designated as E553b in the , is employed as an anti-caking agent in powdered foods such as rice polish, mixes, and coatings to improve flowability and prevent clumping. This usage is limited to dehydrated or powdered products where it acts as a processing aid without altering nutritional content. In pharmaceutical excipients for consumer tablets and capsules, talc acts as a to enhance powder flow during manufacturing, typically at concentrations of 1-2% by weight. Following extensive litigation over talc-based products, major manufacturers like discontinued talc in global baby powder formulations by 2023, transitioning to cornstarch alternatives, even as regulatory bodies continue to approve asbestos-free talc for these uses.

Pharmaceutical and Medical Uses

Sterile talc, a purified and gamma-irradiated form of talc, is employed as a sclerosing agent in procedures to manage recurrent malignant pleural effusions, particularly those associated with or metastatic cancers. Introduced medically in the 1930s, talc induces inflammation and subsequent between the visceral and parietal pleural layers, preventing fluid reaccumulation by obliterating the pleural space. This application relies on talc's inert chemical properties and ability to provoke a localized fibrotic response without systemic when particle size and sterility are controlled. Clinical trials demonstrate high efficacy, with pleurodesis success rates ranging from 80% to 95%, often achieving approximately 90% resolution of effusions when administered as a slurry via chest tube or through thoracoscopic poudrage. For instance, large-particle talc (mean size 24.5 μm) has shown zero incidence of (ARDS) in cohorts with malignant pleural effusions, contrasting with risks from smaller ungraded particles. Administration typically involves 5 grams of talc suspended in saline for intrapleural injection, with success influenced by factors such as complete lung re-expansion prior to instillation and nutritional status. FDA-approved sterile talc products, such as STERITALC, undergo rigorous processing to ensure levels below detectable limits and particle sizes graded to minimize smaller fractions (<10 μm), enhancing injectability and reducing extrapleural dissemination or inflammatory complications. Common side effects include transient fever (up to 38%) and chest pain (13%), but serious adverse events like empyema or hypotension occur infrequently (<1%) with proper technique, distinguishing pharmaceutical-grade talc from non-sterile cosmetic variants lacking such controls.

Safety, Toxicology, and Health Effects

Purity Standards and Grades

Talc is classified into grades primarily based on its mineralogical purity, particle size distribution, and absence of contaminants such as asbestos, heavy metals, and microbial agents, which determine suitability for specific applications. Industrial-grade talc generally exhibits lower purity levels, often ranging from 80% to 95% talc content (Mg₃Si₄O₁₀(OH)₂), incorporating accessory minerals like carbonates, chlorite, or dolomite that do not compromise mechanical properties but preclude use in sensitive sectors. In contrast, cosmetic- and food-grade talc requires greater than 99% purity to minimize irritancy and ensure compliance with safety thresholds for direct human exposure, including limits below 1 ppm for asbestos fibers and trace heavy metals. Pharmaceutical-grade talc demands the highest refinement, achieving ultra-high purity through extensive washing and milling to meet pharmacopeial monographs, rendering it sterile and biocompatible with solubility in dilute acids limited to trace amounts (e.g., water solubility not exceeding 1 in 200). Purity standards are enforced by regulatory bodies and pharmacopeias, with the United States Pharmacopeia (USP) monograph specifying that purified talc must consist predominantly of the theoretical formula Mg₃Si₄O₁₀(OH)₂, free from detectable asbestos via prescribed assays, and compliant with microbial limits (e.g., total aerobic count ≤1000 CFU/g for oral use). The U.S. Food and Drug Administration (FDA) aligns with these for pharmaceuticals and proposes analogous requirements for cosmetics, mandating asbestos absence through validated methods while exempting talc from batch certification as a color additive but scrutinizing contaminants like lead. International equivalents, such as the , impose similar purity criteria, emphasizing acid-insoluble residue and foreign matter limits to affirm talc's chemical inertness in refined forms. Empirical analyses confirm that high-purity talc (>99%) demonstrates negligible reactivity and solubility compared to raw ores, which retain up to 20% impurities altering dissolution profiles in acidic media. Testing protocols for grade certification integrate mineralogical and particulate analyses to quantify purity and contaminants. identifies talc's crystalline structure and accessory phases, detecting asbestos minerals at levels above 0.5-1% but requiring supplementation for trace fibers. coupled with energy-dispersive spectroscopy () and selected area electron diffraction () provides definitive , targeting particles with ratios ≥3:1 and lengths ≥0.5 µm, as proposed in FDA guidelines for cosmetic talc to ensure non-detectability. complements these for bulk screening, enabling rapid assessment of larger samples for fibrous amphiboles or serpentines absent in compliant grades. These methods collectively validate that refined talc grades maintain structural integrity and low impurity profiles, distinguishing them from unprocessed deposits prone to variable composition.

Asbestos Contamination and Detection

Talc and minerals, particularly and , often co-occur geologically in metamorphic deposits due to similar formation processes involving the alteration of ultramafic or dolomitic rocks under hydrothermal conditions, where silica-rich fluids interact with magnesium- and calcium-bearing precursors, yielding both platy talc and fibrous . This association is prominent in contact metamorphic settings, such as those in Death Valley, California, where talc bodies host accessory . While not universal, has been documented in 5-10% of talc ores from historically mined sites, reflecting deposit-specific variability rather than inherent ubiquity. Prior to the , contamination was more prevalent in certain talc ores from U.S. and mines, where unrefined products occasionally contained detectable asbestos fibers due to inadequate separation during early and milling practices; for example, analyses of Pinerolo talc from before 1975 revealed tremolite traces in some samples, though claims of widespread have been contested by subsequent testing showing levels below modern thresholds. U.S. Geological Survey examinations of talc deposits confirmed particles in ores from multiple pre- sites, prompting industry shifts toward source selection and processing refinements by the mid- to minimize carryover. Contemporary detection relies on (PLM) for initial identification of birefringent particles greater than 5 micrometers in length within talc matrices, supplemented by (TEM) coupled with (EDS) and selected area electron diffraction (SAED) to resolve sub-micrometer fibers and confirm mineralogy at concentrations as low as 0.1% by weight. These methods, endorsed by regulatory bodies like the FDA, achieve detection limits approaching 10 fibers per microgram of talc, enabling verification of purity in finished products. Mitigation strategies in modern production include geological screening to avoid amphibole-rich deposits, followed by multi-stage purification via flotation, , and air classification, which routinely produce cosmetic- and pharmaceutical-grade talc with levels below 0.1 fibers per gram—or undetectable by validated assays—in regulated markets, as affirmed by industry safety assessments and peer-reviewed analyses countering assertions of inevitable . Such processes ensure that only asbestos-free talc enters consumer supply chains, with ongoing TEM-based surveillance confirming compliance in products from certified sources.

Inhalation and Respiratory Risks

Chronic of talc dust in occupational settings can lead to talcosis, a form of characterized by granulomatous , foreign body reactions, and progressive due to accumulation of inert talc particles in the lungs. This condition arises primarily from high-dose, prolonged exposure exceeding lung clearance capacity, resulting in overload and interstitial fibrosis rather than the fiber-induced seen in . Talcosis manifests radiographically as small nodular opacities, predominantly in upper lobes, with histopathological evidence of talc-laden s and birefringent particles under polarized light. Mechanistically, pure talc particles, being platy and non-fibrous, provoke a physical overload response where alveolar fail to phagocytose and clear the dust, leading to lysosomal rupture, , and deposition without inherent chemical or carcinogenicity. Animal studies in rats and mice exposed to respirable pure talc at high concentrations (up to 18 mg/m³ for two years) demonstrate dose-dependent and macrophage infiltration but no significant increase in tumors attributable to talc itself, contrasting with effects from asbestos-contaminated samples that mimic through fibrous morphology. These findings align with causal overload models, where correlates with particle burden exceeding 1-2% weight, a rarely reached in controlled human exposures. Epidemiological data from talc miners and millers show low incidence of talcosis in modern operations with ventilation and dust controls, with radiographic abnormalities in less than 5% of workers after decades of exposure, and non-malignant respiratory mortality elevated only in historical cohorts lacking such measures (standardized mortality ratio around 1.5-2.0 for ). Cross-sectional studies of U.S. talc workers report prevalence below 1% when adjusted for and co-exposures, underscoring rarity under OSHA-compliant conditions. Historical cases often involved asbestos-adulterated talc, pure talc effects and inflating perceived risks in unpurified ores. The International Agency for Research on Cancer (IARC) classifies talc not containing or asbestiform fibers as Group 3 (not classifiable as to carcinogenicity to humans) based on inadequate evidence from human inhalation studies and lack of consistent animal tumorigenicity for pure respirable talc. (OSHA) sets a of 20 million particles per (mppcf) for talc dust without , equivalent to about 2 /m³ respirable fraction, to prevent overload . These limits, informed by particle counting rather than mass due to talc's low toxicity, reflect empirical thresholds where adverse effects are negligible in ventilated environments.

Perineal Use and Cancer Epidemiology

Epidemiological investigations into perineal talc application and risk have produced inconsistent findings, with case-control studies frequently reporting relative risks of 20-30% elevation, while prospective studies generally show no significant . A 2020 pooled analysis of four large s encompassing 252,745 women, including data from the , II, Sisters' Health Study, and New England Case-Control Study (prospective components), calculated a of 1.08 (95% CI 0.99-1.18) for ever-use of genital powder, which was not statistically significant after multivariable adjustment for confounders including personal hygiene practices, , and history. Prospective cohorts mitigate inherent in case-control designs, where patients may differentially recollect and report past talc use compared to controls, potentially inflating odds ratios by 5-10% or more in analyses. Quantitative bias assessments indicate that even modest recall differentials attenuate true associations toward the null, rendering many case-control results compatible with no underlying risk. Causal inference is further undermined by the absence of a consistent dose-response relationship in cohort data, where frequency or duration of use does not correlate with escalating risk, as observed in the follow-up spanning decades. Biologically, talc particle migration from the to ovaries via the reproductive tract lacks robust mechanistic support; while trace talc has been detected in some ovarian tissues, the quantities are minimal and insufficient to induce chronic inflammation or oncogenesis, with particle sizes (typically 1-10 μm) exceeding efficient transport through lumens under normal physiological conditions. Animal bioassays administering pure talc intrapleurally or intraperitoneally to rodents have not produced ovarian tumors, contrasting with mesothelioma induction via inhalation, which informs IARC's classification but does not extend to perineal exposure causality. The International Agency for Research on Cancer (IARC) deems talc "probably carcinogenic to humans" () based on limited human evidence for from perineal use and sufficient animal evidence for , but explicitly notes that classifications for asbestos-contaminated talc remain due to , not talc per se; no causal link is established for asbestos-free cosmetic talc in ovarian carcinogenesis. Critiques emphasize that meta-analyses favoring association often overweight biased case-control data and overlook null findings, privileging over causal criteria like , specificity, and experimental consistency. Overall, the epidemiological record does not substantiate causation for pure talc in perineal applications.

Regulatory Assessments and Approvals

The U.S. (FDA) has long regarded cosmetic-grade talc as safe for use in products such as powders and blush when free of contamination. Annual FDA testing of talc-containing , initiated in 2019 and continued through 2023, detected no fibers in surveyed samples, supporting ongoing approvals predicated on purity verification. In December 2024, the FDA proposed mandatory standardized analytical methods—combining and advanced imaging—to detect and identify in talc , aiming to harmonize practices without imposing bans on asbestos-free talc. Talc holds (GRAS) status from the FDA for direct use as a and indirect use in -contact materials, a designation affirmed since the 1970s based on historical safety data for purified forms. It is also listed in FDA's Inactive Ingredient Database for pharmaceutical applications, including oral, rectal, and topical formulations. A May 2025 FDA expert panel reviewed talc's role in and drugs, weighing potential inflammation and cancer links against empirical low-risk profiles for non-contaminated talc, but retained GRAS affirmation pending further data without immediate restrictions. Under the European Union's REACH framework, talc (Mg₃H₂(SiO₃)₄) is registered for industrial, cosmetic, and pharmaceutical uses, with dossiers documenting no intrinsic or for pure talc. The European Chemicals Agency's Risk Assessment Committee (RAC), in September 2024, proposed classifying talc as a Category 1B due to limited evidence of from perineal exposure and lung tumors from inhalation in animal models, though human data remain associative rather than causal and hinge on purity. This classification, if adopted, would mandate warning labels rather than bans, reflecting focused on exposure routes over outright prohibition. The U.S. National Toxicology Program's 1993 Technical Report (TR 421) on non-asbestiform talc via found some evidence of lung tumor induction in female rats and equivocal evidence in male rats, but no carcinogenic activity in mice, underscoring species- and route-specific effects absent human parallels. The concurs that evidence for human carcinogenicity of asbestos-free talc is inadequate, citing inconsistent epidemiologic links to ovarian or cancers and attributing stronger associations to historical asbestos impurities rather than talc itself. These assessments contrast with amplified media portrayals of talc as inherently hazardous, prioritizing instead regulatory consensus on purity controls over unsubstantiated causal claims. Post-2020 developments emphasize proactive purity enforcement: FDA's MoCRA-aligned testing mandates and harmonized labeling proposals enhance detection without empirical justification for bans, as low-dose human exposure data show negligible hazard for compliant, asbestos-free talc. In the 1970s, discoveries of asbestos contamination in certain talc deposits and cosmetic products prompted regulatory scrutiny by agencies like the U.S. (FDA), amid growing awareness of asbestos's carcinogenic properties following the International Agency for Research on Cancer's (IARC) classification of asbestos as a in 1977. Talc producers, including major suppliers to consumer goods manufacturers, responded by implementing voluntary purification standards and testing protocols, asserting that commercial talc had been asbestos-free since around 1976. These early challenges centered on potential trace contaminants rather than proven consumer exposure, with no widespread litigation at the time, as epidemiological studies on purified talc showed no elevated disease rates attributable to the mineral itself. The first documented civil lawsuit alleging health harms from asbestos in talc products was filed in 1999 against Johnson & Johnson, where a plaintiff claimed long-term use of talcum powder contributed to her mesothelioma, highlighting concerns over historical mining practices that could introduce fibrous minerals into talc ores. Subsequent suits through the 2000s primarily invoked failure-to-warn theories, arguing that manufacturers should have disclosed risks of incidental asbestos fibers despite adherence to emerging purity guidelines. Defendants countered with evidence from internal quality controls and third-party analyses indicating that any detected traces were below harmful thresholds and absent in final consumer products, bolstered by cohort studies demonstrating no causal link between refined talc use and respiratory or ovarian pathologies. A 2018 investigation into internal documents from the 1950s to revealed occasional positive tests for in raw talc shipments and, rarely, in finished powders like Shower to Shower from the , fueling claims of inadequate disclosure. maintained that such findings represented isolated anomalies, not systemic issues, and emphasized rigorous testing evolutions that ensured consumer safety, with no verified instances of directly traced to their purified talc in early litigation outcomes. These disputes underscored tensions between geological realities of talc sourcing and advancing analytical detection limits, without establishing causation in the historical cases reviewed.

Major Corporate Lawsuits and Settlements

The multidistrict litigation (MDL) No. 2738, consolidated in the U.S. District Court for the District of , encompasses thousands of lawsuits against (J&J) alleging that its talc-based baby powder products, when applied to the perineal area, caused or due to asbestos contamination. Plaintiffs have claimed that J&J knew of asbestos presence in talc sourced from mines since the but concealed it through manipulated testing and internal documents, while defendants have countered with evidence of rigorous third-party testing confirming asbestos-free status, compliance with FDA standards, and epidemiological studies showing no established causal link between cosmetic talc use and . A critical review of over 30 studies concluded that associations reported in some case-control research (relative risk around 1.3) fail to meet criteria for , such as biological plausibility or dose-response, often confounded by and inconsistent findings across studies. One of the largest verdicts occurred on July 12, 2018, when a St. Louis, Missouri, jury awarded $4.69 billion to 22 women who developed ovarian cancer, including $550 million in compensatory damages and $4.14 billion in punitive damages, finding J&J liable for failing to warn of risks. The award reflected jury assessments of willful misconduct, but subsequent appeals reduced it significantly—to about $550 million total by 2020—highlighting judicial scrutiny of excessive punitive elements disproportionate to proven harm. Similar variability appeared in other trials, such as a 2016 Missouri verdict of $72 million (later reduced) for a single plaintiff and occasional defense wins, like a 2021 California jury rejecting causation claims after reviewing scientific testimony. These outcomes underscore how jury decisions, influenced by emotional testimony and simplified narratives, have diverged from regulatory bodies' findings that asbestos-free talc poses no cancer risk when used as directed. To manage mounting liabilities, J&J pursued resolutions through its LTL Management LLC, filing for Chapter 11 bankruptcy in 2021 and proposing an $8.9 billion settlement in April 2023 to resolve approximately 40,000 claims, contingent on claimant approval and court confirmation under a "Texas two-step" strategy originally structured in . This approach aimed to cap exposure amid verdicts totaling over $6.5 billion across 12 plaintiff-favorable trials since 2014, though actual payouts remained lower due to appeals and the bankruptcy mechanism shielding parent company assets. By 2024, cumulative proposed and partial settlements exceeded $10 billion in value, reflecting economic incentives to avoid protracted trials rather than on scientific , as meta-analyses continue to indicate weak, non-causal associations confounded by other genital factors. Talc America, a key supplier, faced joint liability in early cases like the 2016 Fox verdict ($10 million total, with $50,000 punitive against ), but J&J bore the primary burden as manufacturer.

Recent Developments (2023-2025)

As of October 2025, more than 67,000 talcum powder lawsuits pend against in the U.S. multidistrict litigation (MDL 2738), with claims centered on allegedly linked to perineal application of products containing trace . The volume of asbestos-related filings rose approximately 4% in mid-2025, driven by renewed case influxes following stalled bankruptcy maneuvers, including nearly 1,000 new claims in June 2025 and 294 additional suits between September and October. Johnson & Johnson has allocated over $11 billion cumulatively toward resolutions, including rejected proposals like an $8 billion settlement in March 2025, while declining global consolidations in favor of subsidiary filings— the third of which was dismissed in March 2025. In August 2025, plaintiffs expanded liability to raw talc suppliers, filing suits alleging supply-chain contamination introduced into otherwise purified products destined for consumer formulations. Johnson & Johnson completed its phase-out of talc-based baby powders globally by , substituting cornstarch-based alternatives amid litigation pressures, though such replacements have demonstrated inferior moisture absorption in empirical comparisons for certain applications. Talc products persist in select international markets outside major manufacturers' portfolios. Litigation momentum endures without emergent causal evidence tying cosmetic-grade, asbestos-undetectable talc to ; a 2024 World Health Organization review upheld prior assessments of "probable" carcinogenicity for perineal talc exposure based on associative data, not definitive mechanistic or dose-response validation distinguishing it from confounders like practices or genetic factors.

References

  1. [1]
    [PDF] U.S. Talc—Baby Powder and Much More
    Talc is a hydrous silicate mineral composed of magnesium (Mg), silicon and oxygen (SiO2, silica), and water. Its chemical formula is. Mg3Si4O10(OH)2. Talc is ...
  2. [2]
    Exposure Data - Carbon Black, Titanium Dioxide, and Talc - NCBI
    Schematic structure of talc. 1.1.3. Chemical and physical properties of mineral talc. Hardness: 1 on Mohs' scale. Density: 2.58–2.83. Cleavage: (001) perfect.Chemical and physical data · Production and use · Occurrence and exposure
  3. [3]
    [PDF] CHAPTER 1 MINERALOGY OF TALC - VTechWorks
    Other commercially important properties of talc are its chemical inertness, low abrasion, high thermal conductivity and stability, low electrical conductivity, ...
  4. [4]
    [PDF] Scientific Literature Review Talc as Used in Cosmetics August 15 ...
    Aug 15, 2012 · Talc is used in the leather industry, in the roofing and ceramic tile industry, as a carrier for insecticides and herbicides,13 and it is ...
  5. [5]
    Genital use of talc and risk of ovarian cancer: a meta-analysis
    This meta-analysis resulted in a weak but statistically significant association between genital use of talc and ovarian cancer, which appears to be limited to ...
  6. [6]
    A critical review of talc and ovarian cancer - Taylor & Francis Online
    May 13, 2020 · It is concluded that the evidence does not support a causal association between perineal talc use and ovarian cancer.
  7. [7]
    Quantitative recall bias analysis of the talc and ovarian cancer ...
    Meta-analyses of these studies, driven by the case-control studies' results, have frequently reported a small but statistically significant increase in ovarian ...
  8. [8]
    [PDF] Testing Methods for Detecting and Identifying Asbestos in Talc ... - FDA
    Jan 2, 2025 · Several sampling studies have tested talc-containing cosmetics for asbestos contamination using. TEM. We summarize the results of these ...
  9. [9]
    Talcum Powder and Cancer
    Aug 1, 2024 · Talc that has asbestos is generally accepted as being able to cause cancer if it is inhaled. The evidence about asbestos-free talc is less clear ...
  10. [10]
    DEFINITION FOR TALC. - USGS Publications Warehouse
    Talc is a naturally occurring single-phase mineral having the approximate chemical formula Mg//3Si//4O//1//0(OH)//2 and a specific type of crystal structure.
  11. [11]
    Talc Mineral Data - Mineralogy Database
    General Talc Information. Help on Chemical Formula: Chemical Formula: Mg3Si4O10(OH)2. Help on Composition: Composition: Molecular Weight = 379.27 gm.
  12. [12]
    Talc | H2Mg3O12Si4 | CID 165411828 - PubChem - NIH
    Talc, when it is isolated as a pure mineral, has a composition of 63.6% SiO2, 21.89% MgO, and 4.75% H2O. However, as an industrial commodity, talc rarely ...
  13. [13]
    PHYSICO-CHEMICAL PROPERTIES - Eurotalc
    Talc is a natural mineral (Mg3Si4 O10(OH)2 – molecular weight 379.26). As shown in the opposite figure, its elementary sheet is composed of a layer of ...
  14. [14]
    [PDF] THE CRYSTAL STRUCTURE OF TALC - RRuff
    Talc, ideally Mg3Si4010 (OH)2, is a hydrated magnesium silicate found as a soft crystalline, foliated or compact mineral of white, grey or pale green color and ...
  15. [15]
    The effect of impurities and cleavage characteristics on talc ...
    Jan 30, 2013 · In the case of talc, the impurities that cause the majority of variation in colour are aluminium and iron. Small amounts of Al3 + ions can ...
  16. [16]
    [PDF] Talc: Occurrence, Characterization, and Consumer Applications
    Nontalc minerals associated with commercial talc vary from deposit to deposit and may include calcite, magnesite, dolomite, chlorite, serpentine, and quartz. ( ...
  17. [17]
    [PDF] Phyllosilicates (Micas, Chlorite, Talc, & Serpentine) - Tulane University
    Aug 18, 2015 · Here, the chlorite structure is depicted as consisting of a brucite-like layer (with some. Al) sandwiched between tetrahedral layers that are ...
  18. [18]
    [PDF] TALC RESOURCES OF THE CONTERMINOUS UNITED STATES By
    Talc is very soft and is a standard in the Mohs scale, ... It is commonly described as having a greasy feel and pearly luster (Deer and others, 1962, p.
  19. [19]
    Talc - Minerals Education Coalition
    Talc is the softest mineral on the Mohs hardness scale at 1 and can be easily cut and crushed. Talc has perfect cleavage in one direction.Missing: properties | Show results with:properties
  20. [20]
    Talc | Geology 1501 | ECU
    Luster, Nonmetallic Pearly to Greasy ; Hardness, 1 > Fingernail ; Cleavage, Yes Basal, Not perfect ; Streak, Colorless to White ; Color, Light Greenish to White.Missing: physical Mohs
  21. [21]
    [PDF] The life cycle of a mineral deposit: a teacher's guide for hands-on ...
    Luster—dull to pearly or greasy. • Hardness—1 (can leave mark on paper and ... Best Field Indicators—softness, color, soapy feel, luster, and cleavage.
  22. [22]
    Talc - Etymology, Origin & Meaning
    Talc, from 16th c. French talc, Spanish talco, and Arabic talq, means a magnesium silicate mineral; as a verb, it means to treat or rub with talc.
  23. [23]
    TALC Definition & Meaning - Merriam-Webster
    Etymology. French, from Middle French talk, from Medieval Latin talc, talcum, from Arabic ṭalq ; First Known Use. 1610, in the meaning defined at sense 1 ; Time ...
  24. [24]
    TALC Definition & Meaning - Dictionary.com
    Word History and Origins. Origin of talc. 1595–1605; < Medieval Latin talcum < Arabic ṭalq mica < Persian talk. Discover More. Word History and Origins. Origin ...Missing: derivation | Show results with:derivation
  25. [25]
    TALC - American Heritage Dictionary Entry
    [French, from Medieval Latin talcum and Old Spanish talco, both from Arabic ṭalq, from Persian talk.] The American Heritage® Dictionary of the English ...
  26. [26]
    Revisiting the roots of minerals' names: A journey to mineral etymology
    Aug 30, 2023 · Talc: The term 'Talc' was given by Georgius Agricola in 1564, which is believed to be derived from the Arabic word 'Talq' meaning mica, as it ...
  27. [27]
    [PDF] Soapstone Production through Norwegian History
    This paper covers soapstone production in Norway from prehistoric times to today, including its use for vessels, cooking pots, and even structural purposes in ...
  28. [28]
    Native Americans - The First Geologists in Virginia
    Soapstone has a high percentage of talc, the main component of chalk, so Native Americans could use harder stones to carve out bowls directly from the bedrock.
  29. [29]
  30. [30]
    (IUCr) René-Just Haüy and the birth of crystallography
    Dec 4, 2022 · René-Just Haüy, a French abbot living in Paris, at almost 40 years old, began a scientific career focused on the study of crystals.
  31. [31]
    [PDF] Analysis of an Authentic Historical Italian Cosmetic Talc Sample
    Sep 29, 2017 · Abstract. Italian talc from the Pinerolo Mines in North West Italy is known for its extreme purity. Several historical.
  32. [32]
    History of Soapstone Carving provided by artist Kay McCormack
    The Cretan people of ancient Greece used soapstone to make stamps and receptacles. The Vikings employed soapstone carving skills in much of their jewelry. In ...Missing: discovery prehistoric Americans<|separator|>
  33. [33]
    An Experimental Study of the Formation of Talc through CaMg(CO3 ...
    Jul 4, 2017 · The formation of talc from dolomite and silica-rich fluid occurs at low temperatures in the metamorphism of the CaO–MgO–SiO 2 –CO 2 –H 2 O system.
  34. [34]
    Petrogenesis and timing of talc formation in the Ruby Range ...
    Mar 2, 2017 · Estimates of the maximum conditions of talc formation of 2 kbars and 400 degrees C are based on field observations and heterogeneous phase ...<|separator|>
  35. [35]
    Talc–carbonate alteration of ultramafic rocks within the Leka ...
    Talc–carbonate rocks formed by the breakdown of the serpentine in the previously formed serpentinite rock at temperatures < 550 °C and elevated XCO2, which ...
  36. [36]
    [PDF] Ultramafic-hosted Talc- Magnesite deposits
    May 13, 2006 · Peak metamorphic conditions need to occur in the stability zone of forsterite+antigorite and antigorite+talc assemblages, and the stability ...
  37. [37]
    [PDF] The Mineral Fibers of Potential Concern in Talc | JIFSAN
    Talc deposits are the products of metasomatism caused by regional metamorphism, contact metamorphism, or hydrothermal processes (meteoric fluids or brines ...
  38. [38]
    Formation of talc in the subduction interface: Mg isotopes ...
    Feb 13, 2025 · Talc-rich rocks are formed by passive enrichment of Si in serpentinite during Mg loss to adjacent Mg sinks.
  39. [39]
    Characterization of talc deposits in ultramafic rocks of Gebel El ...
    Apr 24, 2025 · Talc can be formed under laboratory conditions at temperature range of 500-700oC is reported by Kuvart the experiments have shown that, in ...
  40. [40]
    From Mine to Market | Mondo Minerals
    It is formed either through regional or contact metamorphosis of carbonate sediments or through hydrothermal alteration of magnesium-rich magmatic rocks.
  41. [41]
    Formation of the Nkob talc deposit by contact metamorphism and ...
    Talc in ores formed by two processes at Nkob: acicular talc near the granite formed after the breakdown of tremolite in a temperature range of 350 to 500 °C, ...
  42. [42]
    Using the geologic setting of talc deposits as an indicator of ... - USGS
    Hydrothermal talcs, created by siliceous fluids heated by magmas at depth, consistently lack amphiboles as accessory minerals. In contrast, mineable talc ...Missing: processes | Show results with:processes
  43. [43]
    [PDF] U.S. Talc—Baby Powder and Much More
    Significant United States talc deposits occur in the Appalachians and Piedmont, from Vermont to Alabama, and in the West in Montana, California, Nevada, ...
  44. [44]
    [PDF] TALC NOT CONTAINING ASBESTIFORM FIBRES 1. Exposure Data
    These metamorphic rocks crop out in mountain belts such as the Alps, the. Appalachians and the Himalayas and in ancient continental shields such as the Canadian.
  45. [45]
    [PDF] T Hn AMERICAN M INERALOGIST - Mineralogical Society of America
    The serpentinite belts of the Appalachians, Alps, Urals, New South. Wales ... (Tables 1 and 6.) ? Jacobs, E. C., Talc and talc deposits of Vermont: RePort Vt.
  46. [46]
    [PDF] Geology of the Fanjiabauzi Talc Deposit, Liaoning Province, China
    The talc shows exceptionally high quality and purity, which is almost unique worldwide. The Haicheng talc deposit is stated as the world's largest talc deposit ...
  47. [47]
    [PDF] talc and pyrophyllite1 - Mineral Commodity Summaries 2024
    Domestic and world identified resources are estimated to be approximately five times the quantity of reserves. Substitutes: Substitutes for talc include ...
  48. [48]
    [PDF] Talc Resources of the United States - USGS Publications Warehouse
    Talc that contains abundant dark impurities and therefore does not qualify as white-grinding talc is called dark- grinding talc. It is further divided into hard ...<|separator|>
  49. [49]
    How is Talc Mined Extracted? - Vasundhara Minerals
    Jul 24, 2023 · Talc mining involves two primary methods: open-pit mining and underground mining. The choice of technique depends on factors such as deposit depth, size, and ...Missing: beneficiation | Show results with:beneficiation
  50. [50]
    [PDF] AP-42 Background Document for Section 11.26 Talc Processing
    ... crushing, screening, grinding, drying, calcining ... developed for the following sources: crude ore drying, primary crushing, crushed ore rail car loading,.
  51. [51]
    Talc Beneficiation Process - Flotation - 911Metallurgist
    May 26, 2016 · Flotation produces a uniformly pure product at a low cost per ton of ore processed and in addition recovers talc which cannot normally be recovered by dry ...Missing: levels | Show results with:levels
  52. [52]
    Talc Beneficiation Using Column Flotation - TSI Journals
    It is important to optimize the dosages of frothing agent and depressant considering recovered mineral talc purity. Chemical-Technology-powder-recovery.<|control11|><|separator|>
  53. [53]
    [PDF] OCCUPATIONAL EXPOSURE to TALC CONTAINING ASBESTOS
    Water sprays are also used for dust suppression at the 700-ft. level crusher. According to company personnel, wet drilling has been practiced since the ...Missing: avoidance | Show results with:avoidance
  54. [54]
    an assessment of environmental impact of talc processing: flotation ...
    Sep 28, 2025 · This study examines the environmental impacts of talc processing, specifically focusing on flotation and mine water quality.
  55. [55]
    CHEMICAL-SPECIFIC HEALTH CONSULTATION: TREMOLITE ...
    Industrial talc currently mined in New York is called tremolitic talc because it contains significant quantities of nonasbestiform tremolite.
  56. [56]
    Environmental Impact of Talc Mining and Extraction - Tehran Times
    Feb 3, 2024 · Despite its widespread use, talc has been the subject of health concerns due to potential asbestos contamination in natural deposits.Missing: avoidance | Show results with:avoidance
  57. [57]
    Talc Report - Global Trends, Industry Report, Market Size, Growth ...
    Sep 23, 2025 · The Talc Market is expected to reach 8.07 million tons in 2025 and grow at a CAGR of 4.35% to reach 9.98 million tons by 2030.Missing: statistics | Show results with:statistics
  58. [58]
    Top Talc Producing Countries - ReportLinker
    In 2023, China was the leading talc producer at 1.8 million metric tons, followed by India and Brazil with 1.0 and 0.85 million metric tons, respectively.
  59. [59]
    Talc Market Size, Share And Trends | Industry Report, 2030
    The global talc market size was estimated at USD 1.95 billion in 2024 and is projected to reach USD 2.39 billion by 2030, growing at a CAGR of 3.5% from 2025 ...Missing: statistics | Show results with:statistics
  60. [60]
    [PDF] TALC AND PYROPHYLLITE1 - USGS.gov
    Domestic and world identified resources are estimated to be approximately five times the quantity of reserves. Substitutes: Substitutes for talc include ...
  61. [61]
    Global Talc Market Expected to Reach USD 4.0 Billion by 2033
    Mar 7, 2025 · The global talc market size was valued at USD 2.9 Billion in 2024, and it is expected to reach USD 4.0 Billion by 2033, exhibiting a growth rate ...
  62. [62]
    Natural steatite, talc, crushed or powdered exports by country |2021
    $$88,858,384.00In 2021, Top exporters of Natural steatite, talc, crushed or powdered are China ($137,339.63K , 594,891,000 Kg), United States ($133,299.37K , 239,028,000 ...Missing: patterns | Show results with:patterns
  63. [63]
    [PDF] Mineral Commodity Summaries 2022 - Talc and Pyrophyllite
    Total sales (domestic and export) of talc by U.S. producers were estimated to be 490,000 tons valued at about $130 million, a 9% increase from the value in 2020 ...
  64. [64]
    [PDF] THE ISLAMIC STATE, THE TALIBAN, AND AFGHANISTAN'S WHITE ...
    May 17, 2018 · Beyond Nangarhar, mining has been a key revenue source for insurgents, strongmen and illegal militias – and a key driver of instability – across ...
  65. [65]
    Study: Taliban, IS Profit From Illegal Mining of Afghan Talc - VOA
    May 22, 2018 · A new report Tuesday said Islamic State, the Taliban and corrupt power brokers in Afghanistan are making hundreds of thousands of dollars from illegal and ...
  66. [66]
    ISIS, Taliban battle for control over talc mines in Nangarhar
    Jul 11, 2019 · NANGARHAR -- The "Islamic State of Iraq and Syria" (ISIS) is stepping up attacks on the Taliban in Nangarhar Province in a bid to wrest ...
  67. [67]
    Islamic State's Khorasan Province (ISIS-K) – Rewards For Justice
    ... talc mines in Nangarhar, Afghanistan, as well as smuggling these resources out of the country. ISIS-K […] Sanaullah Ghafari. Rewards for Justice is offering ...
  68. [68]
    [PDF] Afghanistan's Minerals: Past and Present | PeaceRep
    The Taliban regime has focused on royalties, which in some cases – talc, for example – has increased threefold. An official from the Core Driller mining company ...
  69. [69]
  70. [70]
    Industrial Applications of Talc Powder | LKAB Minerals
    Apr 23, 2025 · In industrial settings, Talc can be used as a dry lubricant or anti-stick agent in rubber and plastic manufacturing. Due to regulatory changes ...Missing: statistics | Show results with:statistics
  71. [71]
    What is Talc Powder? Discovering Its Role in Plastic Industry
    Dec 17, 2024 · Talc powder is a versatile mineral widely used in various industries, including the plastic sector. It helps improve the quality, enhancing durability and ...
  72. [72]
    Talc in Paper: Enhancing Smoothness, Brightness, and Printability
    Improving Brightness and Whiteness: The natural whiteness of talc contributes to the brightness of the paper, which gives more vivid color prints. Moreover, it ...Missing: inertness | Show results with:inertness<|control11|><|separator|>
  73. [73]
    Analysis of the application characteristics and advantages of talc in ...
    Jan 31, 2025 · It has many excellent properties such as lubricity, fire resistance, acid resistance, insulation, chemical inertness and strong adsorption. In ...Missing: manufacturing benefits whiteness
  74. [74]
    [PDF] bioresources.com - PEER-REVIEW ARTICLE
    Oct 25, 2013 · Talcs have been used in ceramics due to their uniform chemical composition and constant amount of shrinkage over a wide temperature range ( ...
  75. [75]
    Talc and Pyrophyllite Statistics and Information - USGS.gov
    The mineral talc is a hydrous magnesium silicate. A massive talcose rock is called steatite, and an impure massive variety is known as soapstone.Missing: composition | Show results with:composition
  76. [76]
  77. [77]
    Talc in cosmetics and consumer products - Mass.gov
    Jun 1, 2019 · Talc may be used in products to absorb moisture, prevent caking, improve consistency, or to make a product opaque. Talc is an ingredient used ...What is talc? · What types of products may... · What is being done to...
  78. [78]
    Talc - Campaign for Safe Cosmetics
    Talc is a naturally occurring mineral substance used in a variety of cosmetic and personal care products from baby powders to eye shadows.
  79. [79]
    Talc - FDA
    Talc is a naturally occurring mineral, mined from the earth, composed of magnesium, silicon, oxygen, and hydrogen. Chemically, talc is a hydrous magnesium ...
  80. [80]
    Is Talc Safe in Cosmetics? Guide to Talc Safety
    Talc used in cosmetics and pharmaceuticals must meet stringent purity requirements. Pharmaceutical-grade talc is processed to eliminate impurities and meet ...
  81. [81]
    Talc (CI 77718): Cosmetic Ingredient INCI - SpecialChem
    Dec 16, 2022 · Talc is magnesium silicate hydroxide from a rock ore, used in products like baby powder, as an abrasive, absorbent, and bulking agent.
  82. [82]
  83. [83]
    Re‐evaluation of calcium silicate (E 552), magnesium ... - EFSA
    Aug 2, 2018 · ... talc (E 553b) when used as food additives. In 1991, the Scientific Committee on Food (SCF) established a group acceptable daily intake (ADI) ...
  84. [84]
    Talc and calcium carbonate additives for food applications - Imerys
    Calcium carbonate is used for acidity regulation, raising, and thickening. Talc is used for anti-caking, anti-sticking, and as a filler and carrier.
  85. [85]
    E553b (talc) - what is it? | Properties, application | anti-caking agents
    It mainly serves as an anti-caking agent, allowing bulk products such as baking powders, spices, and dietary supplements to maintain their flow and bulkiness.
  86. [86]
    FDA targets talc in food and medicine - C&EN
    Jun 9, 2025 · According to the codex, talc is approved for use in food as an anticaking agent, glazing agent, and thickener, Hansen says. A huge number of ...
  87. [87]
    To use Talc or not to use Talc: Should this even be a Question?
    In the pharmaceutical industry, talc is used primarily as a glidant to improve powder flow in tablet compression. Of course, talc is also used by the personal ...
  88. [88]
    Johnson & Johnson Consumer Health to Transition Global Baby ...
    Aug 11, 2022 · As a result of this transition, talc-based JOHNSON'S® Baby Powder will be discontinued globally in 2023.
  89. [89]
    Johnson & Johnson to replace talc-based powder with cornstarch
    Aug 11, 2022 · By 2023 J&J will make all its baby powder using cornstarch following legal battles over talc's safety.
  90. [90]
    [PDF] Review Talc Pleurodesis in Pleural Disease
    Abstract: Since its first medical use in 1935, talc has become the most frequently used scle- rosing agent for chemical pleurodesis. This review article ...
  91. [91]
    [PDF] STERITALC® (talc), powder, for intrapleural use - accessdata.fda.gov
    STERITALC contains particle size-controlled talc, graded to decrease the proportion of smaller particles. 12. CLINICAL PHARMACOLOGY. 12.1 Mechanism of Action.
  92. [92]
    Thoracoscopic pleurodesis using talc poudrage versus cytotoxic ...
    Talc is highly effective, with success rates from 80% to 95%, relative to the dose, number of administrations and patient's metabolic and nutritional ...<|separator|>
  93. [93]
    Talc Pleurodesis: A Medical, Medicolegal, and Socioeconomic Review
    Oct 5, 2019 · One large study in patients with MPE confirmed efficacy and safety using large particle talc (MPS 24.5 μm), with zero incidence of ARDS.
  94. [94]
    EFFICACY AND SAFETY OF TALC PLEURODESIS IN PATIENTS ...
    The most common side effects of talc pleurodesis was fever (38.3%) and chest pain (13.3%). The serious complication was empyema in 1 patient, hypotension in 1 ...
  95. [95]
    [PDF] STERITALC® (talc), powder, for intrapleural use - accessdata.fda.gov
    Administration of STERITALC at the highest recommended dose of 10 grams may deliver up to 40 mcg of lead. Talc products may contain trace amounts of asbestos. ...
  96. [96]
    Modifying particle size - STERITALC® - Novatech SA
    Talc with an average particle size below 15µm has been shown to induce more severe systemic inflammation and more inflammation in the lungs.
  97. [97]
    Understanding the Three Grades of Talc Powder
    Apr 30, 2024 · 1.2. Cosmetic Grade Talc Powder: Cosmetic grade talc powder also has high purity requirements, particularly in terms of asbestos-free and low ...
  98. [98]
    Talc (Food Grade)
    In Dilute Mineral Acids: Slightly soluble. Application: Industrial, food, Pharmaceutical. Standard: Food Grade. Purity: 99%. Usage: Cosmetics ...
  99. [99]
    [PDF] Revision Bulletin Official August 1, 2011 Talc 1
    Pure talc has the formula Mg3Si4O10(OH)2. It may water (1 in 200). Transfer 4.0 mL of this solution to a contain variable amounts of associated minerals ...
  100. [100]
    Understanding Talc Grades: Pharmaceutical vs. Cosmetic vs ...
    Pharmaceutical Grade Talc Powder: This grade is subjected to the most rigorous purification processes. It must be exceptionally pure, free from asbestos and ...
  101. [101]
    USP Monographs: Talc - USP29-NF24
    If intended for oral administration, the total aerobic microbial count does not exceed 1000 cfu per g, and the total combined molds and yeasts count does not ...
  102. [102]
    Testing Methods for Detecting and Identifying Asbestos in Talc ...
    The Food and Drug Administration (FDA, the Agency, or we) is proposing to require testing of talc-containing cosmetic products using standardized testing ...
  103. [103]
    Purified Talc IP / BP / USP / Ph. Eur. / JP - APJ Industries Pvt. Ltd.
    Purified Talc IP / BP / USP is a white mineral powder used in pharmaceuticals and cosmetics as a glidant, lubricant, anticacking agent, carrier and filler.<|separator|>
  104. [104]
    [PDF] Safety Assessment of Talc as Used in ... - CIR Report Data Sheet
    Sterile talc is approved as a sclerosing agent.56 Sterile talc powder ... Talc is not allowed for use on the surface of medical gloves.57. Talc is used ...<|separator|>
  105. [105]
    <901> Detection of Asbestos in Pharmaceutical Talc - USP-NF
    Apr 30, 2021 · The new chapter will provide detailed testing procedures and instructions for users to perform analysis and data interpretation of x-ray powder diffraction ( ...
  106. [106]
    Testing Methods for Detecting and Identifying Asbestos in Talc ...
    Dec 27, 2024 · Therefore, combining TEM, which enables detection of smaller fibers, with PLM, which enables testing of larger samples, gives the best chance of ...
  107. [107]
    [PDF] Procedure for the Analysis of Talc for Asbestos | JIFSAN
    Talc analysis for asbestos uses polarized light microscopy (PLM), transmission electron microscopy (TEM), and sometimes X-ray diffraction (XRD). TEM is useful ...
  108. [108]
    [PDF] A USGS Study of Talc Deposits and Associated Amphibole Asbestos ...
    In addition to the previously recognized tremolite, EDS analyses indicated that a number of the asbestiform particles in talc ores from several mines have ...
  109. [109]
    Using the geologic setting of talc deposits as an indicator of ...
    Aug 7, 2025 · Examples of contact metamorphic deposits occur in Death Valley, California; these talc-tremolite deposits contain accessory amphibole-asbestos.
  110. [110]
    [PDF] Occupational Exposure to Talc Containing Asbestos US ... - Index of /
    The respiratory effects of exposure to talc containing 10 percent "bladed" tremolite in two Georgia talc mines and mills were reported by Dreessen and Dalla ...
  111. [111]
    FDA Issues Proposed Rule on Testing Methods for Asbestos
    Dec 26, 2024 · FDA does not currently require any specific method or approach to test for asbestos in talc-containing cosmetic products. We propose to require ...
  112. [112]
    [PDF] Safety Assessment of Talc as Used in Cosmetics
    Dec 18, 2012 · Talc used in cosmetics does not contain asbestiform fibers; asbestiform refers to a crystallization product of a mineral in which the crystals ...
  113. [113]
    [PDF] Asbestos in Talc Breakout Session B November 28, 2018 - FDA
    Nov 28, 2018 · The cosmetic grade talcs consist of mixtures. People select talcs from different deposits, blend these talcs. And talcs have a certain color.
  114. [114]
    Talcum induced pneumoconiosis following inhalation of adulterated ...
    Mar 15, 2012 · Talc deposition in the lungs typically causes granulomatous inflammation characterized by formation of foreign body granulomas of varying degree ...Missing: empirical | Show results with:empirical
  115. [115]
    Inhalation Toxicity of Talc | Journal of Aerosol Medicine and ...
    Talc toxicity studies show that talc particles and fibers are durable and can remain in the lung for up to 40 years after the end of exposure. This extended ...
  116. [116]
    Inhalational Talc Pneumoconiosis: Radiographic and CT Findings in ...
    We present the radiographic and CT manifestations and serial changes on chest radiographs of 14 patients with pathologically proved talc pneumoconiosis.Missing: studies | Show results with:studies<|separator|>
  117. [117]
    Talc Inhalation in Rats and Humans - NIH
    The human studies show that talc can induce COPD and lung fibrosis in workers exposed to high levels to talcum powder.
  118. [118]
    Systematic review of the scientific evidence of the pulmonary ...
    Oct 10, 2022 · Across the animal studies assessing chronic talc toxicity, results largely demonstrate a lack of talc carcinogenicity. Although two of the ...
  119. [119]
    Risk of Mortality from Respiratory Malignant and Non ... - NIH
    Oct 5, 2022 · This systematic review and meta-analysis provides evidence that men working in the talc mining industry have increased mortality for non-malignant respiratory ...
  120. [120]
    [PDF] chapter 16 health studies of miners and millers exposed to talc
    This cross-sectional morbidity study involves miners and millers working with talc from four major talc-producing regions. The composition of the.
  121. [121]
    Talc pneumoconiosis: A pathologic and mineralogic study
    This study shows that “talcosis” frequently represents disease associated with a variety of minerals and that talc is a common denominator.
  122. [122]
    Talc (IARC Summary & Evaluation, Supplement7, 1987) - INCHEM
    Feb 10, 1998 · Talc not containing asbestiform fibres is not classifiable as to its carcinogenicity to humans (Group 3). Talc containing asbestiform fibres is carcinogenic to ...Missing: pure respirable
  123. [123]
    Talc (containing no asbestos and less than 1% quartz) - CDC
    Exposure Limits. NIOSH REL. TWA 2 mg/m3 (resp). OSHA PEL. TWA 20 mppcf See Appendix C (Mineral Dusts) See Appendix G. Measurement Methods. NIOSH P&CAM355 (III)
  124. [124]
    TALC (NOT CONTAINING ASBESTOS) - OSHA
    Jan 12, 2021 · Health factors: See NIH-NLM PubChem. IDLH. 1000 mg/m³. Carcinogenic classifications: IARC-3, TLV-A4, Notes: AIHA emergency response planning ...Missing: pure | Show results with:pure
  125. [125]
    Association Between the Frequent Use of Perineal Talcum Powder ...
    Feb 2, 2022 · We found frequent use of perineal talcum powder is associated with an increased risk of ovarian cancer, with a pooled adjusted odds ratio of ...
  126. [126]
    Prospective Study of Talc Use and Ovarian Cancer - Oxford Academic
    In this study, we conducted a prospective analysis of perineal talc use and the risk of ovarian cancer. METHODS: The Nurses' Health Study is a prospective study ...
  127. [127]
    Quantitative recall bias analysis of the talc and ovarian cancer ... - NIH
    To better understand the potential impact of recall bias on the results of case-control studies of perineal talc use and ovarian cancer, we conducted a ...
  128. [128]
    Talc, ovarian cancer, and recall bias in the sister study - ScienceDirect
    This bias is likely present in all studies that retrospectively assessed past talc use after ovarian cancer diagnoses.
  129. [129]
    The impact of recall bias on the association between talc and ...
    Aug 25, 2024 · Assuming even a modest degree of recall bias (5-10%) led to attenuated ORs for talc use and ovarian cancer, with 95% simulation intervals (SIs) that span the ...
  130. [130]
    Quantitative Bias Analysis of Talc and Ovarian Cancer - Gradient Corp
    Mar 21, 2024 · In this new study, the potential impact of recall bias on the results reported in case-control studies was evaluated in a quantitative recall ...
  131. [131]
    [PDF] IARC Monographs evaluate the carcinogenicity of talc and acrylonitrile
    Jul 5, 2024 · An increased rate of ovarian cancer was also observed in studies looking at occupational exposure of women exposed to talc in the pulp and paper ...
  132. [132]
    Carcinogenicity of asbestos-free talc and talcum powder - PubMed
    No increase in cancer risk is apparent among miners and millers of asbestos-free talc; risk for ovarian cancer increases following the perineal use of ...Missing: contamination | Show results with:contamination
  133. [133]
    [PDF] IARC Monographs evaluate the carcinogenicity of talc and acrylonitrile
    Jul 5, 2024 · The Working Group classified talc as probably carcinogenic to humans (Group 2A) on the basis of a combination of limited evidence for cancer in ...Missing: pure respirable
  134. [134]
    Systematic review of the association between talc and female ...
    Aug 7, 2023 · We also concluded that there is suggestive evidence of no association between genital talc application and endometrial cancer.
  135. [135]
    FDA Confirms No Asbestos in Cosmetic Talc Products for a Third ...
    Apr 16, 2024 · The US Food and Drug Administration (FDA) confirmed that its third-party testing of cosmetic talc products for 2023 identified no traces of asbestos.
  136. [136]
    FDA Proposes Rule to Require Standardized Testing Methods for ...
    Dec 26, 2024 · The proposed rule would require manufacturers of talc-containing cosmetic products to test for asbestos using an analytical approach.
  137. [137]
    Reviewing the Safety of our Foods and Drugs: An Urgent Need for a ...
    Apr 10, 2025 · Talc is also a texturizing, anti-sticking agent. Beyond its use in cosmetic and medical products, it is used in virtually all kinds of flavored ...<|separator|>
  138. [138]
    Talc Safety in Pharma, Food & Cosmetics: Risks and Regulatory ...
    Aug 19, 2025 · While recent regulatory discussions have heightened scrutiny, the FDA has not prohibited talc in foods, drugs, or cosmetics; however, purity and ...
  139. [139]
    FDA Convenes Panel Evaluating the Role of Talc as a Food Additive
    Jun 16, 2025 · On May 20, 2025, the US Food and Drug Administration (FDA) held a panel to discuss the “safety and necessity” of talc as an additive in food and drugs.<|separator|>
  140. [140]
    Talc (Mg3H2(SiO3)4) - Registration Dossier - ECHA
    The excess risk for ovarian cancer was also highest for women under the age of 55 years at diagnosis, with an SIR of 8.0 (six observed; 95% CI, 2.9–17.4) for ...
  141. [141]
    Highlights from September RAC and SEAC meetings - ECHA
    Sep 26, 2024 · RAC assessed a vast database of information on Talc and concluded that there is sufficient evidence that exposure to Talc may cause cancer.
  142. [142]
    ECHA Issues CLH Opinion Regarding Talc Labelling and ...
    Aug 14, 2025 · Talc should be classified as a Category 1B carcinogen (“presumed to be carcinogenic to humans”) under the EU Classification, Labelling, and ...
  143. [143]
    [PDF] Talc (CASRN 14807-96-6)(Non-Asbestiform) in F344/N Rats and ...
    These studies are designed and conducted to characterize and evaluate the toxicologic potential, including carcinogenic activity, of selected chemicals in ...
  144. [144]
    J&J knew for decades that asbestos lurked in its Baby Powder
    Dec 14, 2018 · One of those labs found asbestos in Shower to Shower talc from the 1990s, according to an Aug. 11, 2017, court report. Another lab found ...
  145. [145]
    A Review of the Talc Industry's Influence on Federal Regulation and ...
    This narrative review examines the talc industry's role in delaying and ultimately blocking federal regulation of cosmetic talc from the 1970s to today.
  146. [146]
    Statement on Reuters Talc Article - Johnson & Johnson
    Dec 14, 2018 · Johnson & Johnson's baby powder is safe and asbestos-free. Studies of more than 100,000 men and women show that talc does not cause cancer or ...Missing: 2013 | Show results with:2013
  147. [147]
    Johnson & Johnson Asbestos and Talc | Mesothelioma Guide
    Dec 20, 2022 · As Johnson & Johnson continued production of its Baby Powder, the first asbestos claim against the pharmaceutical giant came in 1999 from a ...Missing: earliest | Show results with:earliest<|separator|>
  148. [148]
    Talcum Powder & Asbestos: Cancer from Asbestos in Talc
    Industrial talc has the highest asbestos levels reaching 50% to 70%. Since the late 1960s, tests of cosmetic talc found asbestos levels from 0% to 30%. Asbestos ...
  149. [149]
    Johnson & Johnson responds to recent news coverage on talc
    Dec 16, 2018 · When discussing testing in litigation, Reuters reports that a lab “found asbestos in Shower to Shower talc from the 1990s, according to an Aug.Missing: contamination | Show results with:contamination
  150. [150]
    Talc, Asbestos, and Epidemiology: Corporate Influence and ...
    We know of no evidence that the talc mining and manufacturing companies tested products or mined talc for fibrous talc after 1970. At least 32 epidemiologic ...
  151. [151]
    Talcum Powder Settlements - Verdicts & Payouts (October 2025)
    The bulk of cases against J&J are consolidated in multidistrict litigation (MDL 2738) ... Johnson & Johnson Agrees To Pay States $700 Million To Settle Talcum ...Latest Updates · How Long Does It Take?
  152. [152]
    Jury orders J&J to pay $4.7 billion in Missouri asbestos cancer case
    Jul 12, 2018 · A Missouri jury on Thursday ordered Johnson & Johnson to pay a record $4.69 billion to 22 women who alleged the company's talc-based products, including its ...
  153. [153]
    Perineal Talc Use and Ovarian Cancer: A Critical Review - PMC
    A meta-analysis of studies of anti-inflammatory drug use found no reduction in ovarian cancer risk (Bonovas et al., 2005). Inflammation induces pleural fibrosis ...
  154. [154]
    Jury Awards $4.7 Billion To Women In Johnson & Johnson Talcum ...
    Jul 13, 2018 · Johnson & Johnson has been ordered to pay nearly $4.7 billion in damages to 22 women and their families who say asbestos found in the company's talcum powder ...
  155. [155]
    Talcum Powder Lawsuit Verdicts & Settlement Amounts
    Slemp claimed to have used J&J's baby powder and Shower to Shower talc products for more than 40 years leading up to her diagnosis with ovarian cancer in 2012.
  156. [156]
    Johnson & Johnson Reaches Deal for $8.9 Billion Talc Settlement
    Johnson & Johnson said on Tuesday that it had agreed to pay $8.9 billion to tens of thousands of people who claimed the company's talcum powder products caused ...
  157. [157]
    J&J unit files for second bankruptcy to pursue $8.9 billion talc ...
    Apr 5, 2023 · J&J unit files for second bankruptcy to pursue $8.9 billion talc settlement ... J&J's original Texas two-step bankruptcy, filed in October 2021.
  158. [158]
    Talcum Powder Lawsuit | September 2025 Update - Levin Papantonio
    Our law firm has secured over 150 jury verdicts of $1 million or more and achieved verdicts and settlements totaling more than $80 billion. Our lawyers will put ...
  159. [159]
    Talc Powder Ovarian Cancer Lawsuit - Lawsuit Information Center
    Sep 29, 2025 · J&J proposed a $6.5 billion settlement to resolve baby powder ovarian cancer lawsuits, contingent on a supermajority agreement (75%) from ...
  160. [160]
    The Association Between Talc Use and Ovarian Cancer
    Apr 1, 2016 · Risks for epithelial ovarian cancer from genital talc use vary by histologic subtype, menopausal status at diagnosis, HT use, weight, and smoking.
  161. [161]
    Talcum Powder Lawsuit Settlements - Levin Sedran & Berman LLP
    She was awarded $66 million from Johnson & Johsnon, $39 million from J&J Consumer and $50,000 from Imerys, J&J talc supplier, in punitive damages, as well as ...Missing: excluding | Show results with:excluding
  162. [162]
    Talcum Powder Lawsuit | 2025 Update & Settlements
    The company's subsidiary, Red River Talc LLC, had proposed a $9 billion settlement to resolve over 60,000 lawsuits alleging that its talc-based products caused ...
  163. [163]
    Talcum Powder Lawsuit - Ovarian Cancer Claims (October 2025)
    Johnson & Johnson (J&J) faced 67,204 pending talcum powder lawsuits in multidistrict litigation in New Jersey as of October 2025. MDL 2738 is before Judge ...Why Are People Filing Talcum... · J&J Talcum Powder Updates
  164. [164]
    Talcum Powder Lawsuit | October 2025 J&J Litigation Updates
    October 2025: The total number of claims in the Johnson & Johnson Talcum Powder Products MDL is now 67,204. March 2025: A Texas judge dismissed the Chapter 11 ...
  165. [165]
    Johnson & Johnson Talcum Powder Lawsuit | Updated Oct. 2025
    Oct 9, 2025 · November 2024: With their latest trial loss, J&J has now been ordered to pay a total of $320 Million in mesothelioma lawsuit verdicts for 2024 ...
  166. [166]
    Talcum Powder & Ovarian Cancer Lawsuit - October 2025 Update
    Rating 4.9 (159) Oct 16, 2025 · J&J faces thousands of lawsuits alleging that its talcum powder products caused women to develop ovarian cancer and mesothelioma. This verdict ...<|separator|>
  167. [167]
    Talc Suppliers Face Lawsuits Following Raw Material ...
    Aug 25, 2025 · Monday, August 25, 2025 - Companies that sell raw talc are being sued because of asbestos contamination that is said to have gotten into ...
  168. [168]
    J&J to stop selling talc-based baby powder globally in 2023 - CNBC
    Aug 11, 2022 · Johnson & Johnson will stop selling talc-based baby powder globally in 2023, the drugmaker said on Thursday, more than two years after it ended US sales.
  169. [169]
    Talc Is Suddenly in the Spotlight. Is it Bad for You? - Time Magazine
    Jul 24, 2025 · In a 2024 review, the World Health Organization found that, overall, evidence doesn't prove talc causes cancer, but it's “probably carcinogenic.
  170. [170]
    Can Talcum Powder Cause Cancer? - WebMD
    Aug 10, 2025 · Scientists say it's clear that people who breathe in talc with asbestos are more likely to get cancer, especially if they do it regularly. The ...<|control11|><|separator|>