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Controlled ecological life-support system

A Controlled ecological life-support system (CELSS) is a bioregenerative technology that integrates biological, chemical, and physical components to create a closed-loop environment for sustaining human life in space, recycling waste materials such as carbon dioxide, water, and nutrients into essential resources like oxygen, food, and potable water through processes involving photosynthetic organisms like plants and algae.^[1] These systems aim to minimize resupply needs for long-duration missions, such as those to the Moon or Mars, by mimicking Earth's ecological cycles in a controlled, compact setup.^[2] Developed primarily through NASA's research in the 1980s and 1990s, CELSS represents an evolution from physico-chemical life support methods toward sustainable, self-regenerating habitats.^[3] Key components of a CELSS include higher plants for food production and oxygen generation, microbial systems for waste decomposition and nutrient recycling, and supporting infrastructure for atmospheric control, water purification, and lighting—often using energy-efficient LEDs to optimize growth under space constraints.^[4] For instance, wheat cultivation in CELSS prototypes requires approximately 18–20 square meters to meet one person's daily caloric needs of 2,800 calories, with ongoing research targeting reductions to 6–7 square meters through genetic and environmental improvements.^[1] These elements work in concert to achieve high material closure rates, such as 98.2% in advanced bioregenerative designs.^[5] Historically, NASA's CELSS program, initiated in the early 1980s, built on Soviet experiments like BIOS-3 in the 1960s, which demonstrated partial closure with algae and plants supporting crews for months.^[3] Milestones include the 1987 Biomass Production Chamber for vertical farming tests and the 1990s Breadboard Project, a 68-cubic-meter facility simulating integrated operations.^[1] Although NASA's dedicated CELSS efforts ended in 2004, the concepts influenced international programs, such as China's Lunar Palace 1, which from 2017 to 2018 sustained crews in a year-long experiment (Lunar Palace 365) achieving 98.2% material closure.^[5] The European Space Agency's MELiSSA project continues component-level research, focusing on microbial loops for waste processing.^[6] As of 2025, CELSS technologies underpin bioregenerative life support strategies for sustainable lunar and Mars exploration, with advancements including Antarctic analog testing and studies on plant responses to altered gravity.^[7]^[8] China's National Space Administration leads operational advancements toward the International Lunar Research Station in the 2030s.^[3] Challenges persist in system stability, radiation resistance, and automation, but recent innovations in LED lighting and crop genetics promise enhanced reliability.^[9] As space agencies prioritize deep-space missions, CELSS remains crucial for reducing logistical burdens and enabling indefinite human presence beyond Earth.^[10]

Introduction and Historical Origins

Definition and Core Principles

A Controlled Ecological Life Support System (CELSS) is a bioregenerative technology designed to sustain human life in isolated environments, such as long-duration space missions, by recycling essential resources including air, water, food, and waste through integrated biological and physico-chemical processes.^[11] This system aims to create a self-sustaining loop where human metabolic outputs are converted back into usable inputs, minimizing the need for resupply from Earth and enabling extended operations in resource-constrained settings.^[9] The term CELSS was coined by NASA in the early 1980s as part of its efforts to advance regenerative life support beyond traditional open-loop systems.^[9] At its core, a CELSS operates on the principle of mass balance within closed ecological loops, where the total mass of key elements like carbon, oxygen, hydrogen, and nitrogen remains conserved through continuous recycling, supported by external energy inputs such as artificial lighting.^[4] Biological components, including higher plants for photosynthesis and microbial communities for waste decomposition, drive the regeneration: plants consume carbon dioxide exhaled by crew members and produce oxygen, edible biomass, and potable water, while physico-chemical processes like filtration and chemical reactors serve as backups or supplements to ensure system stability.^[12] A basic mass flow concept involves crew consumption of oxygen, water, and food leading to outputs of carbon dioxide, urine, feces, and perspiration, which are then processed—biologically via bioreactors or chemically via distillation—to close the loop and return purified resources.^[4] Key performance metrics for CELSS include closure rates, which measure the percentage of resources recycled within the system, typically targeting 90-98% efficiency for air, water, and food to reduce resupply mass significantly.^[4] Reliability is paramount, with designs emphasizing ultra-low failure rates (e.g., less than 1 in 10,000 per major component) through redundancy and modular construction to prevent mission-critical disruptions.^[13] Scalability accommodates varying crew sizes, from small teams of 4-6 for planetary outposts to larger groups of 20+ for space stations, by adjusting the volume and capacity of growth chambers and processing units proportionally.^[14]

Original Concepts and Early Proposals

The concept of controlled ecological life-support systems (CELSS) emerged in the mid-20th century amid the space race, drawing from early visions of self-sustaining habitats for long-duration missions. In the 1950s, both the United States and Soviet Union explored simple biological systems using algae, particularly Chlorella species, to produce oxygen through photosynthesis while recycling carbon dioxide and waste. These proposals stemmed from military research on submarines and high-altitude flights, where algae were seen as efficient, compact organisms for maintaining air quality in enclosed environments.^[15]^[16] Pioneering devices included the Continuous Culture Chamber developed by Jack Myers at the University of Texas at Austin, which sustained small animal populations by integrating algal growth with waste processing, and the Microterella system by William Oswald and Clarence Golueke at the University of California, Berkeley, which demonstrated water purification alongside oxygen generation.^[15] Soviet efforts paralleled this, with the Institute of Biomedical Problems (IBMP) conducting initial experiments on microalgae cultivators in the early 1960s, achieving up to 90% gas exchange closure in small-scale cabins over several weeks.^[17] By the late 1960s and into the 1970s, these algal models evolved toward more integrated ecosystems incorporating higher plants, influenced by the limitations of short Apollo-era missions that relied on open-loop systems with resupply from Earth. NASA's formalization of the CELSS program in 1978, under the Life Sciences Division, built on these foundations to address extended missions, proposing regenerative loops for air, water, and food using photosynthetic organisms.^[9] Key Soviet contributions included Josef I. Gitelson's leadership at the Institute of Biophysics in Krasnoyarsk, where he advanced proposals for closed systems combining humans, algae, and plants, culminating in the BIOS-3 facility's design and construction in the late 1960s.^[17]^[16] These early ideas shifted from purely physicochemical methods to bioregenerative approaches, emphasizing the Earth's biosphere as a model for spacecraft sustainability, though implementation remained theoretical until ground-based testing.^[16] Early proposals faced significant hurdles in energy efficiency and microbial stability, constraining their practicality. Algal systems demanded precise control of lighting and temperature, often relying on artificial sources that increased energy demands beyond solar availability in space, while imbalances in nutrient cycling led to inefficiencies in oxygen output.^[15] Microbial stability proved elusive, as uncontrolled growth in closed volumes caused pH fluctuations, trace element accumulations like iron and zinc, and ecosystem disruptions that threatened long-term viability.^[17]^[16] Despite these challenges, the concepts laid the groundwork for viewing CELSS as ecosystems requiring balanced recycling of resources to mimic natural biogeochemical cycles.^[9]

Rationale for CELSS

Challenges in Long-Duration Space Missions

Long-duration space missions face severe resource limitations due to the finite availability of air, water, and food in isolated environments far from Earth. Oxygen supplies deplete as crew members consume it for metabolism, while carbon dioxide accumulates from exhalation, necessitating constant monitoring and partial recovery systems that currently reclaim only about 50% of oxygen from CO2 on the International Space Station (ISS). Water is equally constrained, with each crew member requiring approximately 3.8 liters per day for drinking, food preparation, and hygiene, yet total body water decreases by about 1% during flight due to fluid shifts in microgravity. Food provisions are limited by shelf-life stability, typically 18-24 months for most items, which is insufficient for Mars missions spanning 2-3 years round-trip without resupply opportunities. Resupply missions to Mars are further complicated by launch windows occurring every 26 months, resulting in potential delays of 6-18 months for delivery after the 6-9 month transit time. Health risks exacerbate these logistical challenges, particularly in microgravity, where astronauts experience 1-1.5% bone mineral density loss per month and significant muscle atrophy, increasing fracture risks and complicating post-mission recovery. Exposure to space radiation poses heightened dangers, including elevated cancer incidence and potential central nervous system damage from galactic cosmic rays, which are unshielded in deep space. Psychological isolation compounds these issues, leading to stress, anxiety, fatigue, sleep disturbances, and cognitive impairments from confinement in small habitats, with communication delays to Earth reaching up to 20 minutes one-way for Mars missions. The absence of natural environments, such as green spaces, can worsen mental health, as prolonged isolation mimics extreme Earth analogs like Antarctic stations. Sustainability issues in open-loop systems highlight the impracticality of indefinite resupply dependence, with the ISS requiring approximately 3 metric tons of consumables per crew member annually, including oxygen, water, and food, despite recycling 90-98% of water from urine and sweat. Waste accumulation, particularly non-recycled organic matter like feces and uneaten food, contributes to mass buildup and lost resources, as current systems vent or store it without full reclamation. CO2 buildup in closed cabins reaches levels about 10 times higher than on Earth, impairing cognition and contributing to conditions like Spaceflight Associated Neuro-ocular Syndrome if not scrubbed regularly. Oxygen depletion in unmitigated scenarios could render habitats uninhabitable within hours for a full crew, underscoring the need for regenerative approaches in extended missions. These challenges are particularly acute for mission types like lunar bases, Mars habitats, and deep space exploration under programs such as Artemis, which aim for sustained human presence on the Moon starting with short stays but extending to year-long surface operations. Lunar missions must contend with the South Pole's steep terrain and limited resources, while Mars habitats face total autonomy for durations up to 500 days due to resupply infeasibility. Deep space transits, such as those to Mars or beyond, amplify distance-related risks, with no real-time Earth support and cumulative exposure to hazards over months or years.

Advantages Over Open Systems

Controlled ecological life-support systems (CELSS) offer substantial resource efficiency compared to open systems, which rely on expendable supplies and frequent resupply missions. In open systems, all water, air, and food must be carried or delivered, leading to linear increases in mass and volume requirements as mission duration extends. CELSS, by contrast, achieves high recycling rates through biological processes, such as plant-based water recovery exceeding 90% efficiency, drastically reducing launch mass for long-duration missions beyond one year. For instance, NASA analyses indicate that CELSS can reach a break-even point for mass savings after approximately two months in low-Earth orbit for a four-person crew, with up to 97% closure for food production, enabling greater autonomy without proportional resupply needs.^[18]^[4]^[4] Beyond material conservation, CELSS provides multifunctionality that enhances crew well-being in confined space environments. Traditional open systems deliver processed, stored food, which lacks freshness and variety, potentially impacting nutrition and psychological health during extended isolation. CELSS integrates plant cultivation to produce fresh vegetables and oxygen, supporting dietary needs while offering visual and sensory benefits from greenery that boost morale and reduce stress. Studies within NASA's CELSS program highlight how such elements, like growing potatoes or wheat in controlled areas, contribute to psychological resilience by simulating natural environments and providing a sense of agency over sustenance.^[4]^[4] CELSS designs also demonstrate superior resilience through inherent biological redundancy, contrasting with the vulnerability of open systems to single-point failures in supply chains. Biological components, such as diverse plant species and microbial processes, provide natural buffering against perturbations, allowing the system to self-regulate and recover from faults like equipment malfunctions or environmental fluctuations. This fault-tolerant structure minimizes risks in remote missions, where resupply delays—such as those exceeding months to Mars—could otherwise compromise operations. NASA's evaluations emphasize how this redundancy supports stable performance over multi-year durations, lowering long-term operational costs through reduced dependency on external logistics.^[4]^[4] Finally, the scalability of CELSS makes it adaptable to varying crew sizes and mission lengths, addressing the escalating demands of deep-space exploration. Open systems scale poorly, as consumable mass grows directly with personnel and time, straining launch capabilities for larger teams or extended stays. CELSS mitigates this by modularly expanding biological modules—such as adding cultivation areas for additional crew—while maintaining high closure rates, supporting missions from four-person outposts to larger habitats lasting over a decade. This flexibility aligns with NASA's projections for lunar and Mars bases, where CELSS enables sustainable operations without indefinite resupply.^[9]^[9]

Fundamental Components

Air Revitalization Systems

Air revitalization systems in controlled ecological life-support systems (CELSS) primarily rely on biological processes to regenerate oxygen (O₂) and remove carbon dioxide (CO₂) produced by human respiration and metabolic activities.^[19] These systems utilize photosynthesis in higher plants and algae to convert CO₂ into breathable O₂, mimicking natural atmospheric cycles in a closed environment.^[4] For instance, wheat plants have been studied for their efficiency in O₂ production and CO₂ scrubbing due to their high biomass yield and adaptability to controlled conditions.^[19] Similarly, algae such as Chlorella pyrenoidosa offer compact, high-rate gas exchange, with systems requiring approximately 300 liters of algal culture per person per day under optimized conditions.^[19] Photosynthetic efficiency depends on light intensity, typically ranging from 600 to 1000 µmol/m²/s at the canopy level to achieve adequate rates of CO₂ uptake and O₂ release, with higher levels supporting elevated CO₂ environments.^[20] Physico-chemical methods serve as reliable backups to biological systems, ensuring redundancy during periods of instability such as plant growth cycles or algal culture failures.^[21] The Sabatier reaction, a catalytic process, reduces CO₂ by reacting it with hydrogen (H₂) to produce methane (CH₄) and water (H₂O), which can then be electrolyzed to recover O₂.^[21] The reaction proceeds as follows:

\ce{CO2 + 4H2 ⇌ CH4 + 2H2O}

Operated at temperatures of 150–350°C with nickel or ruthenium catalysts, this method avoids solid byproduct accumulation, allowing CH₄ venting or further processing.^[21] Trace gases, including volatile organic compounds (VOCs) from human activity or biological off-gassing, are removed using adsorbents such as granular activated carbon beds integrated into filtration units. These adsorbents capture contaminants through physical and chemical adsorption, maintaining air purity without relying solely on biological filtration.^[22] Continuous monitoring is essential to maintain safe atmospheric composition, employing sensors for key parameters like O₂ concentration (nominally 21% partial pressure), CO₂ levels (limited to <0.5% or 0.4 kPa partial pressure), and relative humidity (40–70%). These sensors, often luminescence-based or non-dispersive infrared types, provide real-time data to adjust system operations and prevent deviations that could impair crew health.^[23] The air loop's mass balance is governed by the simplified photosynthetic equation, where inputs of CO₂ and H₂O yield outputs of O₂ and biomass:

\text{Input: CO₂ + H₂O → Output: O₂ + biomass}

This balance ensures stoichiometric equivalence between gas exchanges in the crew-photosynthesizer loop.^[19] Advanced CELSS designs target over 95% closure efficiency for air revitalization, as demonstrated in integrated models combining biological and physico-chemical elements; recent ESA MELiSSA project tests as of 2025 have shown component closures exceeding 98%.^[24]^[25] Algae-based systems, for example, can achieve >75% O₂ recovery from CO₂, with potential for higher rates through optimized lighting and nutrient delivery.^[26] However, challenges persist, such as VOC buildup from plant volatiles or microbial activity, which can degrade air quality and require enhanced adsorbent capacities or periodic venting to sustain long-term operation.

Food Production and Consumables

In controlled ecological life-support systems (CELSS), food production relies on the cultivation of high-yield, nutrient-dense crops selected for their efficiency in constrained space environments. Key candidates include potatoes, soybeans, and wheat, which offer substantial biomass and caloric potential while minimizing growth area requirements. These crops are typically grown using hydroponic or aeroponic systems, where roots are suspended in nutrient-rich solutions or mist, eliminating soil and optimizing water and space use in microgravity. For instance, NASA's Biomass Production Chamber experiments demonstrated that such setups can support viable yields of root and tuber crops like potatoes under controlled conditions.^[27]^[28] Nutritional balance in CELSS food systems aims to meet crew requirements of approximately 2,500–3,400 kcal per person per day, alongside essential macronutrients and micronutrients, through a diverse crop portfolio. Proteins can be sourced from soybeans or algae, such as Spirulina, which provides up to 70% protein by dry weight and supports amino acid profiles comparable to animal sources. Vitamins and antioxidants are supplemented by leafy greens like lettuce and radishes grown in systems like NASA's Veggie, which yield fresh produce without significant nutritional degradation in space. Models indicate that a 40–50 m² growing area per crew member can fulfill full caloric needs when integrating high-harvest-index crops, though supplemental algae reduces this to 35–40 m² by enhancing protein density.^[29]^[30]^[31] Beyond direct sustenance, food production in CELSS generates oxygen as a byproduct of photosynthesis, where plants convert crew-exhaled CO₂ into O₂ at rates sufficient to offset human respiration in balanced systems. Waste materials from crew and crops serve as fertilizers, closing the nitrogen cycle through processes like nitrification, where ammonia (NH₃) from waste is oxidized to nitrates (NO₃⁻) for plant uptake, enhancing resource recycling efficiency.^[4]^[32] Challenges in CELSS food production include optimizing lighting with LED spectra tailored to photosynthetic needs, achieving up to 3 μmol/J efficiency with far-red supplementation to boost biomass. Pollination for fruiting crops like dwarf tomatoes requires manual intervention in microgravity, while harvest cycles demand precise timing to maintain yields. Genetic modifications, such as engineering root architectures for better nutrient uptake or enhancing radiation tolerance, are emerging to improve overall efficiency; as of 2021, NASA's research explores biotechnological approaches including CRISPR-edited plants for space environments.^[30]^[33]^[34]

Water Recovery and Waste Processing

In controlled ecological life-support systems (CELSS), water recovery is essential for achieving high material closure rates, with urine processing representing a primary source of reclaimable water. Urine, which constitutes a significant portion of wastewater, is pretreated to remove solids and then distilled using vapor compression distillation (VCD), a phase-change technology that evaporates water at low temperatures and condenses it for reuse. This method achieves recovery rates of 85-95% from pretreated urine, depending on system design and operational conditions, as demonstrated in NASA-developed prototypes for space applications.^[35]^[36] Additionally, humidity condensate from crew activities and plant transpiration is collected via dehumidifiers and filters, providing a supplementary water stream with minimal processing needs due to its lower contaminant load.^[37] As of 2023, the International Space Station's water recovery system, incorporating VCD, has achieved up to 98% overall water recovery from urine and other sources, informing hybrid CELSS designs.^[38] Waste processing in CELSS integrates biological methods to convert solid and liquid wastes into recoverable resources, minimizing mass loss and enabling nutrient cycling. Anaerobic digestion reactors break down organic solids from feces, inedible plant biomass, and food production residues into biogas and digestate, which can be further stabilized for use as fertilizer precursors. These systems operate under oxygen-limited conditions to favor methane-producing microbes, achieving organic matter reduction efficiencies of up to 70-80% while generating energy through biogas capture.^[39]^[40] Emerging integrations, such as microbial fuel cells (MFCs), enhance waste treatment by oxidizing organics in wastewater to produce electricity alongside water purification, with pilot studies showing power densities of 0.1-1 W/m² in space-relevant configurations.^[41] Recovered water must meet stringent purity standards to ensure crew safety, typically requiring total organic carbon (TOC) levels below 3 ppm and total contaminants under 10 ppm to prevent health risks from microbial or chemical exposure. Post-processing steps, including catalytic oxidation and ion exchange, polish the distillate to these thresholds. The water cycle in CELSS follows a regenerative loop: liquid inputs (urine, condensate) undergo evaporation or transpiration, followed by condensation and recovery, with inefficiencies primarily from purge losses (5-15%).^[42]^[43] Integration of water recovery with waste processing facilitates urine-to-fertilizer conversion, where concentrated residuals from distillation are mineralized via struvite precipitation or nanofiltration to extract nutrients like nitrogen and phosphorus for plant growth. However, challenges include biofilm formation in distillation units, which reduces efficiency through fouling and requires periodic chemical cleaning, and odor management in anaerobic reactors, addressed via gas scrubbing or biofilters to maintain cabin air quality.^[44]^[45] These processes ensure that wastes from food production serve as inputs, closing the nutrient loop without external resupply.^[46]

Design and Operational Concepts

Closed vs. Controlled Ecosystems

Closed ecological life-support systems represent an idealized design philosophy aiming for complete material recycling with no external inputs or outputs, achieving a theoretical mass balance of zero net loss through fully self-sustaining biological and physicochemical processes.^[4] Such systems seek to mimic Earth's biosphere in a sealed environment, where all air, water, food, and waste are regenerated internally, as exemplified by the Biosphere 2 experiment, which attempted total closure but encountered significant challenges.^[47] In contrast, controlled ecological life-support systems (CELSS) adopt a more pragmatic approach, targeting 90-98% closure rates with periodic resupply to maintain functionality, often integrating hybrid bioregenerative elements like plants or algae with physicochemical components for enhanced stability.^[4] These systems allow for limited external inputs, such as nutrients or oxygen supplements, to compensate for inefficiencies in recycling loops for air and water, ensuring reliable operation over extended periods.^[4] Key trade-offs between the two designs highlight the risks of pursuing full closure, including potential instability from imbalances in gas exchange or nutrient cycles, as seen in oxygen depletion events that can lead to system crashes without intervention.^[47] Controlled systems mitigate these by enabling real-time adjustments through environmental sensing and hybrid redundancies, trading absolute self-sufficiency for greater robustness and predictability, though at the cost of ongoing resupply logistics.^[4] The evolution of CELSS designs reflects a shift from the ambitious closed-system ideals prominent in 1970s conceptual work toward controlled architectures in modern NASA frameworks, prioritizing scalable integration of biological and engineering controls for long-duration missions.^[9] This transition, formalized with the program's initiation in 1978, emphasizes practical efficiency over theoretical perfection to address real-world stability and cost constraints.^[9]

System Integration and Monitoring

In controlled ecological life-support systems (CELSS), integration strategies emphasize modular designs that allow for scalable interconnection of components, such as bioreactors for plant growth and microbial processors, to facilitate efficient material and energy flows while maintaining system balance.^[48] These modules are linked through shared interfaces for air, water, and nutrients, enabling phased implementation from small-scale prototypes to full crew-supporting units.^[4] Feedback loops are integral, using dynamic adjustments to regulate processes like carbon dioxide uptake by plants and oxygen release, ensuring homeostasis across the ecosystem.^[49] Monitoring technologies in CELSS rely on advanced sensor networks to track critical parameters in real time, including pH levels, nutrient concentrations, gas compositions, and biomass growth, often integrated with computer-based control systems for automated responses.^[48] Emerging approaches incorporate AI-driven analytics, such as convolutional neural networks for waste classification and predictive modeling to optimize resource recovery, enhancing the precision of adjustments in hybrid biological environments.^[50] Redundancy protocols are embedded in these systems, with duplicate sensors and parallel data streams to prevent single-point failures during long-duration operations.^[4] Control models for CELSS employ system dynamics simulations to predict and maintain stability, often based on mass balance principles represented by the equation \frac{dM}{dt} = I - O - L, where M is the mass of a key resource (e.g., carbon or water), I denotes inputs from production processes, O represents outputs to crew consumption, and L accounts for losses due to inefficiencies or leaks.^[49] Hierarchical control frameworks, including model predictive control, coordinate these simulations across modules to handle variability in crew demands and environmental perturbations.^[51] Fault management in CELSS incorporates hybrid architectures that combine biological elements with physico-chemical backups, such as electrochemical oxygen generators and vapor-phase catalytic water processors, to ensure continuity if bioregenerative components fail.^[52] These systems are designed for scalability to support 4-6 crew members, with built-in redundancies like buffer tanks for gases and multiple production pathways to mitigate risks from microbial imbalances or equipment degradation.^[4]

Historical and Notable Projects

Early Ground-Based Experiments

Early ground-based experiments on controlled ecological life-support systems (CELSS) began in the 1960s, primarily driven by space agencies in the Soviet Union and the United States, to simulate closed-loop life support for long-duration missions. These terrestrial tests focused on integrating biological components like algae and higher plants for air revitalization, food production, and waste recycling, aiming to achieve high degrees of material closure without external inputs. Initial efforts emphasized small-scale prototypes to validate concepts before scaling to human-inhabited facilities.^[53] The Soviet Union's BIOS-3 facility, operational from the early 1970s through the 1980s at the Institute of Biophysics in Krasnoyarsk, Siberia, represented a pioneering effort in human-rated closed systems. This 315-cubic-meter facility supported crews of two to three individuals for up to six months, achieving approximately 95% air closure through a combination of Chlorella algae (providing about 75% of oxygen regeneration) and higher plants (contributing 25%). Algae were cultivated in stacked tanks under artificial light, while plants like wheat and vegetables occupied dedicated compartments for food production, yielding up to 50% of caloric needs. Water recovery approached near-complete levels via evaporation-condensation cycles and biological processing in plant and algal units. Challenges included maintaining gas exchange balance and managing microbial populations, but the experiments demonstrated stable operation over extended periods.^[53]^[54] In the United States, NASA's CELSS Breadboard Project, initiated in 1985 at the Kennedy Space Center, built on these concepts by developing and integrating subsystems for a one-person scale. The project's Biomass Production Chamber (BPC), a 113-cubic-meter sealed environment,^[55] tested air revitalization, food production with crops such as wheat, soybeans, and potatoes, and water recovery through hydroponic systems and waste mineralization. Atmospheric closure was documented with a leak rate below 5% of volume per day, while subsystem tests achieved partial material recycling, such as enzymatic conversion of cellulose waste to sugars for reuse. Experiments ran through the late 1980s and into the 1990s, providing baseline data on crop yields and engineering controls, though full-system closure remained at 50-70% for air and water loops due to integration challenges. Key outcomes included successful six-month aquaculture trials with tilapia and lettuce, highlighting the need for robust microbial management in hydroponics to prevent contamination.^[56]^[57]^[54] The Biosphere 2 project (1991-1993), a privately funded endeavor in Arizona, scaled up to an 8-person crew in a 1.27-hectare sealed enclosure mimicking Earth's biomes. Intended to test full ecological closure for space applications, it achieved less than 10% annual atmospheric exchange but encountered severe imbalances, including oxygen depletion from 21% to 14% over 16 months. This was primarily caused by microbial respiration consuming oxygen while oxidizing excess organic matter in the soils, compounded by carbon dioxide reacting with concrete to form carbonates. Crop failures in the agricultural biome exacerbated food shortages, with the system producing only about 80% of required calories despite diverse plantings. These issues underscored the critical role of microbial diversity in ecosystem stability, as uncontrolled soil bacteria drove unforeseen biogeochemical cycles, leading to lessons on pre-experiment soil sterilization and microbial monitoring for future designs.^[47]^[54] Overall, these 1960s-1990s experiments established foundational data on closure rates ranging from 78-95% in advanced tests like BIOS-3 to partial achievements in subsystem-focused efforts, revealing the importance of balanced microbial communities to prevent gas imbalances and support long-term viability. They informed subsequent CELSS development by emphasizing integrated testing and the risks of ecological unpredictability in closed environments.^[53]^[54]

Space-Based Implementations

Space-based implementations of controlled ecological life-support systems (CELSS) have primarily occurred aboard the International Space Station (ISS), where experiments have tested bioregenerative technologies in microgravity to validate their viability for long-duration missions. These efforts build on ground-based validations by adapting systems to orbital conditions, focusing on air revitalization, food production, and water recycling within closed loops. Key integrations include NASA's Vegetable Production System (Veggie), activated in 2014, which enables the growth of leafy greens like lettuce in a compact, LED-illuminated chamber using hydroponic pillows for nutrient delivery.^[58] Veggie has supported multiple harvests, including the first consumption of 'Outredgeous' red romaine lettuce by astronauts in 2015 after a 28-day growth cycle, demonstrating safe, fresh food production without soil.^[59] The European Space Agency's (ESA) MELiSSA project, initiated in the late 1980s, has contributed through microbial and algal tests on the ISS, such as Arthrospira (spirulina) cultures for oxygen production and CO2 fixation, with the ArtEMISS-A experiment planned for Increment 22 (2009-2010) and subsequent flights in the 2010s.^[60] Outcomes from these implementations highlight partial closure achievements alongside microgravity-specific challenges. The ISS water recovery system, incorporating urine processors and water processors, has reached efficiencies of up to 98% as of 2023, recycling metabolic water, humidity condensate, and hygiene effluents into potable water, though early phases targeted a minimum 85% recovery.^[61]^[62] In plant growth, Veggie experiments achieved successful lettuce yields but encountered fluid dynamics issues, such as inadequate root zone aeration due to poor air-liquid separation and over-saturation from floating water droplets, necessitating manual wicking and design iterations like the Plant Water Management (PWM) demonstrations starting in 2021.^[63] These challenges stem from the absence of buoyancy-driven flow, leading to uneven nutrient distribution in hydroponics and increased risk of anaerobic conditions in roots.^[63] NASA's Advanced Life Support (ALS) program, active from the 1990s through the 2010s, drove much of this progress by integrating CELSS elements into hybrid physico-chemical-biological systems for ISS upgrades and exploration vehicles. The ALS emphasized reducing equivalent system mass (ESM) through regenerative tech, achieving ESM metrics of 2.03 for ISS-like facilities by 2004, compared to baseline ECLSS, via components like Sabatier reactors for oxygen recovery and bioreactors for waste processing.^[64] Hybrid approaches in ALS testing combined algal photobioreactors with chemical systems, enabling up to 97% closure in simulated scenarios for air and water loops, though orbital hybrids on ISS reached around 70% overall resource closure by blending Veggie food production with existing ECLSS.^[4] Key milestones from 1998 to 2022 include the ISS assembly beginning in 1998 with initial ECLSS modules laying groundwork for CELSS testing; 2000s ALS integrations testing CO2 reduction tech on Shuttle-Mir and early ISS; 2014 Veggie activation and 2015-2016 lettuce harvests marking first in-space CELSS food consumption; 2015 MELiSSA algal experiments from ISS; and 2021 PWM hydroponics demos achieving >99% bubble separation for improved fluid control.^[64]^[59]^[63] These steps demonstrated CELSS feasibility in space, with hybrid systems reducing resupply needs by 30-50% in models.^[64]

Recent Developments and Future Directions

Advances in Bioregenerative Technologies

Recent innovations in bioregenerative technologies for controlled ecological life-support systems (CELSS) have focused on synthetic biology to enhance microbial processes for waste management. In 2024, NASA researchers advanced the use of synthetic microbial communities to recycle space waste streams, enabling efficient biomanufacturing of resources like oxygen and nutrients from organic waste, thereby supporting closed-loop sustainability in long-duration missions.^[65] These efforts incorporate advancements in synthetic biology to improve the robustness of microbial recycling, reducing reliance on resupply missions. Advancements in plant cultivation technologies have leveraged synthetic biology to develop crops with higher yields and enhanced resilience for CELSS environments. By 2025, synthetic biology applications in space exploration have contributed to engineering plants for improved stress tolerance and nutritional profiles in extraterrestrial settings.^[66] These developments prioritize traits for growth in harsh environments, drawing from investments in space agriculture research to ensure viable yields in extraterrestrial settings. Integration of hybrid bio-regenerative loops has achieved material closure rates exceeding 90% in advanced CELSS models. A 2025 system-of-systems design for lunar bases outlines a phased approach where bio-regenerative components, combined with physicochemical processes, reach 98% total closure for water, air, and carbon cycles in fully mature stages, with food self-sufficiency at 62.7%.^[67] This hybrid configuration uses microalgae, higher plants, and microbial bioreactors to process waste into usable resources, minimizing mass loss to below 2% and demonstrating scalability through computational modeling of interconnected loops.^[67] International efforts continue to drive progress, with the European Space Agency's (ESA) MELiSSA project providing key updates on closed-loop bioregenerative systems. The MELiSSA project advances wastewater recycling and microbial photobioreactors for nutrient recovery in pilot facilities. These developments align with global market projections for environmental control and life support systems, expected to grow from $2.3 billion in 2022 to $4.5 billion by 2030 at a CAGR of 8.9%, fueled by investments in bioregenerative technologies for sustainable space habitation.^[68]

Applications for Lunar and Martian Exploration

Controlled ecological life-support systems (CELSS) are pivotal for enabling sustainable human presence on the lunar surface through NASA's Artemis program, which aims to establish outposts beginning in the late 2020s. These systems integrate bioregenerative technologies to recycle air, water, and waste, reducing reliance on Earth resupply for missions lasting months to years. For instance, the Artemis program's Lunar Gateway and surface habitats will initially depend on physicochemical systems, but experts emphasize the need for hybrid CELSS to achieve long-term viability, drawing on historical NASA research from the 1980s–2000s that demonstrated plant-based oxygen production and food growth in controlled environments.^[3] China's Lunar Palace 1 facility, in its "Lunar Palace 365" experiment, sustained a four-person crew for 370 days with 98.2% material closure, serving as a model for adapting such systems to lunar conditions.^[69] In-situ resource utilization (ISRU) enhances CELSS efficiency on the Moon by extracting water from regolith, providing essential inputs for plant cultivation and crew hydration. A 2024 NASA modeling study evaluated interconnected ISRU processes for lunar water extraction and purification, achieving yields sufficient to support initial habitat needs while minimizing launch mass. Thermal extraction methods, such as oven-based heating of icy regolith, can recover volatiles at rates enabling up to 10–20% of water requirements from local sources, integrating directly with CELSS hydroponic modules.^[70]^[71] These approaches align with Artemis timelines, targeting operational ISRU demonstrations by Artemis III in mid-2027 and scaled production for permanent bases by the early 2030s.^[72] For Martian exploration, CELSS must address unique environmental challenges, including 0.38g partial gravity and recurrent dust storms that reduce solar power availability by up to 80% during global events, impacting energy-intensive bioregenerative processes like lighting for crop growth. Lower gravity affects plant morphology and nutrient uptake, necessitating designs tested in analogs to ensure stable yields of staples like potatoes and lettuce. Evolving from International Space Station (ISS) technologies, Martian CELSS concepts target 98% closure for water and air, building on ISS achievements where brine processing recovers 98% of wastewater, adapted for Mars' longer missions with hybrid physicochemical-biological loops.^[73]^[74]^[75] NASA's CHAPEA (Crew Health and Performance Exploration Analog) mission, launched in June 2023, prototyped hybrid CELSS elements in a year-long Mars surface simulation, where crews managed limited resources, grew crops in a 20-square-meter garden producing 10–15% of caloric needs, and recycled water to 90% efficiency under constrained conditions. This 1,700-square-foot habitat incorporated bioregenerative components like aeroponic systems alongside physicochemical air revitalization, validating integrated operations for dust-mitigated power and partial-gravity analogs.^[76] The second CHAPEA mission, which began in October 2025, continues to refine these hybrids toward 98% closure targets.^[77] Looking to the 2030s, CELSS deployment timelines align with crewed lunar bases by 2028–2030 under Artemis and initial Mars missions by 2035–2039, as outlined in the 2024 Global Exploration Roadmap. Lunar outposts will scale CELSS to support 4–10 crew members with ISRU-augmented food production covering 30–50% of needs, while Mars bases aim for full bioregenerative independence to counter 6–9 month transit isolation. These systems will evolve from current prototypes, prioritizing modular designs for expansion into sustainable habitats.^[78]^[3]

Physico-Chemical Life Support

Physico-chemical life support systems provide essential environmental control for human spaceflight by using physical and chemical processes to regenerate air, water, and thermal conditions without relying on biological components. These systems are particularly suited for short- to medium-duration missions where reliability and compactness are paramount, as demonstrated by their implementation in the International Space Station (ISS) Environmental Control and Life Support System (ECLSS). Core technologies include water electrolysis for oxygen production and adsorption-based scrubbers for carbon dioxide removal, enabling partial closure of resource loops while minimizing mass and volume requirements.^[79]^[80] Oxygen generation primarily occurs through electrolysis of water, governed by the reaction:

$2H_2O \rightarrow 2H_2 + O_2

In the ISS Oxygen Generation Assembly (OGA), ultrapure water is fed into a proton exchange membrane electrolyzer stack, producing oxygen for cabin delivery and venting hydrogen overboard. This process operates at efficiencies exceeding 91% in power supply module (PSM) terms, with nominal production rates supporting up to 5.4 kg of oxygen per day for a four-person crew. Carbon dioxide removal employs regenerative adsorption systems, such as the four-bed Carbon Dioxide Removal Assembly (CDRA), which uses zeolite molecular sieves to capture CO2 from cabin air through pressure-swing adsorption; captured CO2 is then desorbed and vented, with potential for closed-loop integration in future configurations. These technologies have been refined through iterative testing, with the CDRA demonstrating capacity for six person-equivalents of CO2 removal in dual-bed mode.^[79]^[80]^[80] Advantages of physico-chemical systems include high operational reliability and compact design, critical for space-constrained environments like the ISS, where the ECLSS has maintained continuous functionality since 2000 with modular upgrades. For instance, 2023 enhancements to the water processing assembly achieved 98% recovery efficiency from wastewater sources, including urine and humidity condensate, without biological augmentation—far surpassing earlier targets and reducing resupply demands. Electrolysis efficiency can be quantified as voltage efficiency, \eta_v = \frac{1.23}{V_{cell}}, where 1.23 V is the theoretical reversible potential and V_{cell} is the applied cell voltage; practical systems achieve 70-90% efficiency by minimizing overpotentials through advanced catalysts and membranes. These attributes make physico-chemical approaches robust for missions requiring predictable performance, such as orbital stations.^[62]^[81]^[79] Despite their strengths, physico-chemical systems have notable limitations, including the inability to produce food, necessitating ongoing resupply for nutrition, and higher energy consumption compared to fully regenerative alternatives—electrolysis alone demands approximately 3.6 kW for nominal ISS operations. The energy-intensive nature arises from processes like heating for desorption in CO2 scrubbers and distillation in water recovery, contributing to overall system power loads of 10-15 kW for a six-person crew. Additionally, while air and water loops achieve high closure, the open-loop venting of hydrogen and CO2 limits full resource recycling.^[79]^[82]^[83] Hybrid configurations integrate physico-chemical components as reliable backups within controlled ecological life-support systems (CELSS), enhancing overall system resilience for long-duration missions; for example, ISS ECLSS serves as a baseline for lunar gateway designs where physico-chemical units handle primary air revitalization alongside biological food production. This approach leverages the proven durability of chemical processes to mitigate risks during CELSS scaling.^[84]^[85]

Earth-Based Regenerative Systems

Earth-based regenerative systems adapt principles from controlled ecological life-support systems (CELSS) to terrestrial environments, emphasizing biological recycling of water, nutrients, and waste for sustainable agriculture and habitat resilience. These systems prioritize closed or semi-closed loops to minimize resource consumption, drawing on ecological integration to address challenges like water scarcity and urban food security without the isolation required for space applications. A key analog is Biosphere 2, constructed in Arizona between 1987 and 1991 as the world's first soil-based, bioregenerative life-support facility to test closed ecological dynamics for human habitation.^[86] Initially designed to simulate Earth's biosphere in a sealed 3.14-acre structure containing diverse biomes like rainforests and deserts, it demonstrated the potential for self-sustaining oxygen production and food cycles through integrated plant, animal, and microbial communities.^[87] Since the 1990s, Biosphere 2 has evolved into a premier Earth systems research center under the University of Arizona, focusing on regenerative ecosystem studies such as carbon cycling and soil restoration, with ongoing experiments in landscape evolution and water management that inform global sustainability efforts.^[88] This transition highlights its role in advancing regenerative technologies adaptable to planetary conditions, including gravity-assisted growth and limited external energy inputs. Urban vertical farms represent a practical application, stacking hydroponic or aeroponic layers in controlled indoor environments to boost yields while conserving resources, directly inspired by CELSS research on efficient crop production in confined spaces. In Singapore, Sky Greens' vertical farming towers utilize automated, low-energy systems to grow leafy greens, achieving 5 to 10 times the productivity of traditional soil-based farms per square meter and reducing water use by up to 95% through recirculation.^[89]^[90] Similarly, carbon-neutral greenhouses employ CELSS-like loops by capturing CO2 from internal processes for plant uptake, integrating solar-powered climate controls to reuse up to 70% of water and energy, as seen in systems like GreenCap's adaptive enclosures that maintain zero-emission operations year-round.^[91] In desert regions, closed-loop hydroponic farms, such as those deployed in the Middle East during the 2020s, recycle nutrients and desalinated water to cultivate crops with over 90% less consumption than open-field methods, enabling viable agriculture in arid zones like the UAE.^[92]^[93] For disaster relief habitats, modular regenerative systems inspired by CELSS provide rapid-setup, soil-less growing units that support food production in crisis zones with minimal infrastructure. Hydroponic greenhouses, for instance, have been implemented in conflict-affected areas like Lebanon to address food insecurity, using 90% less water and land to yield fresh produce in portable, resilient structures deployable amid natural disasters or insecurity.^[94]^[95] These Earth-adapted designs differ from space CELSS by leveraging ambient gravity for stable plant orientation and permitting selective external inputs, such as supplemental rainwater or ambient air exchange, to enhance system reliability and scalability in variable terrestrial conditions.^[4] Overall, these regenerative approaches yield benefits like drastic water savings—often 90-98% reductions—and increased food security, positioning them as vital tools for urban and remote sustainability.^[96]^[97]

References

[1]
[PDF] N88-12259 - NASA Technical Reports Server
A CELSS (Controlled Ecological Life Support System) is a device that utilizes photosynthetic organisms and light energy to regenerate waste materials into ...
[2]
The Controlled Ecological Life Support Systems (CELSS) research ...
Sep 1, 1990 · The goal of the Controlled Ecological Life Support Systems (CELSS) program is to develop systems composed of biological, chemical and physical components
[3]
Critical investments in bioregenerative life support systems for ...
Aug 16, 2025 · Such approaches were the foundation of the NASA Controlled Ecological Life Support Systems (CELSS) program, which led to the NASA ...
[4]
[PDF] Controlled Ecological Life Support System
Space travel by humans depends upon the reliable operation of life support systems. The life support systems in general use today are reliable and.
[5]
Development of Nitrogen Recycling Strategies for Bioregenerative ...
Recent research on both improvements and developments of the MELiSSA ... controlled ecological life support system. Water Supply 19, 718–724. doi ...
[6]
[PDF] The NASA CELSS Program
Such a system will have eco- nomic benefits, radically lowering costs of mission life support, mission operations benefits by sub- stantially reducing the need ...
[7]
Progress and prospect of research on controlled ecological life ...
Controlled ecological life support system (CELSS) is an effective way to guarantee the survival of astronauts for the long-term manned deep space ...
[8]
Controlled Ecological Life Support System - CELSS
The Controlled Ecological Life Support System (CELSS) Program, a NASA effort to develop bioregenerative systems which provide required life support elements ...Missing: developments | Show results with:developments
[9]
Controlled Ecological Life Support System
Central to the CELSS concept is the Plant Growth Chamber, where green plant photosynthesis produces food, and aids in the production of oxygen and water.
[10]
[PDF] Ultra Reliable Closed Loop Life Support for Long Space Missions
If the mission overall Loss of Crew requirement is 1 in 1,000, each of the major mission elements such as life support must have a 1 in 10,000 or 1 in 100,000 ...Missing: CELSS scalability size
[11]
[PDF] controlled ecological life support systems (celss)
1.0 INTRODUCTION. 1.1 OVERVIEW. Waste management subsystems are a key element in Controlled Ecological Life. Support Systems (CELSS) operations. These ...
[12]
Of Astronauts and Algae | Environmental Humanities
Nov 1, 2017 · Drawing on archival and published sources, I detail the history of the bioregenerative life-support system, a system in which simple organisms— ...Abstract · Algae In The Atmosphere · Nasa Gets Ecological
[13]
[PDF] A History of Life Support Systems in the Space Age
From the early 1960s onward, American and Soviet life scientists and environmental engineers were remarkably informed about sustainable resource management. As.
[14]
[PDF] Closed Ecological Systems, Space Life Support and Biospherics
Experimental work on creating biological life support systems on the basis of closed loop, internal material cycling, started in the Soviet Union in the 1960s.
[15]
https://read.dukeupress.edu/environmental-humanities/article/9/2/359/133023/Of-Astronauts-and-AlgaeNASA-and-the-Dream-of
[16]
[PDF] N88-12255 - NASA Technical Reports Server (NTRS)
Concepts of a CELSS anticipate the use of photosynthetic organisms (higher plants and algae) for air revitaliza- tion. The rates of production and uptake of ...
[17]
[PDF] Controlled Ecological Life Support System
Soon after the CELSS program research a c t i v i t i e s began in the early 1980's, the Principal Investigators in the Food Production.Missing: origin | Show results with:origin
[18]
[PDF] The Development of Models for Carbon Dioxide Reduction ...
Reduction can be achieved through a number of techniques. NASA is currently exploring the Sabatier reaction, the Bosch reaction, and co- electrolysis of CO2 ...Missing: CELSS | Show results with:CELSS
[19]
[PDF] Atmosphere Revitalization Technology Development for Crewed ...
Atmosphere revitalization uses separation processes like adsorption and filtration, and reaction processes like chemical adsorption, oxidation, and reduction. ...Missing: CELSS | Show results with:CELSS
[20]
[PDF] Compact Multi-gas Monitor for Life Support Systems Control in Space
Jul 17, 2014 · Luminescence-based fiber optic sensors performing phase-resolved measurements to monitor oxygen, carbon dioxide, humidity and temperature in ...Missing: CELSS | Show results with:CELSS
[21]
[PDF] Life Support Goals Including High Closure and Low Mass Should Be ...
Jul 20, 2017 · ... 95% closure.” (Wieland,. 90-3728) Percent closure was replaced by ESM as the major metric for life support research and development in the.
[22]
[PDF] Thirsty Walls: A New Paradigm for Air Revitalization in Life Support
Biological algae based systems can credibly achieve >75% oxygen from CO2. 6) The single greatest impact on launch mass of an ECLS system is water. The best ...
[23]
[PDF] Crop Production for Advanced Life Support Systems
Additional crop recommendation panels were commissioned by CELSS and ALS programs and findings from these panels and other groups have been published in several.Missing: m²/ | Show results with:m²/<|control11|><|separator|>
[24]
Growing root, tuber and nut crops hydroponically for CELSS
Therefore, hydroponics system has been evaluated for growing potatoes, sweet potatoes, sugar beets and peanuts for controlled ecological life support system ( ...
[25]
[PDF] Nutritional Models for - NASA Technical Reports Server
In these expanded models, an optimal CELSS diet is defined as one that satisfies as nearly as possible a set of constraints including many of the vitamins and ...
[26]
Supplemental Food Production With Plants: A Review of NASA ...
Nov 9, 2021 · Here we review some of NASA's research and development (ground and spaceflight) targeting fresh food production systems for space.
[27]
[PDF] Potential for Utilization of Algal Biomass for Components of the Diet ...
Results showed that processing of green algae to protein isolate enhances its potential nutritional and organoleptic accep- tability as a diet component in ...
[28]
Optimizing Nitrogen Fixation and Recycling for Food Production in ...
Plant and human waste can be proportionally fed into a combination of aerobic and anaerobic digesters to promote nitrification and mineralization. These ...
[29]
Biotechnological development of plants for space agriculture - Nature
Oct 14, 2021 · Recently, genetically manipulating the root system architecture has become an emerging strategy to increase nutrient acquisition and yield in ...
[30]
[PDF] Elevating the Use of Genetic Engineering to Support Sustainable Plant
Genetic engineering of the plant cell wall could also improve the accessibility of cellulose in the cell wall to make more accessible feedstocks for space ...
[31]
[PDF] £ife Systems, Jnc. - NASA Technical Reports Server
The advanced preprototype Vapor Compression Distillation Subsystem was designed to reclaim 95% of the available wastewater at a nominal water recovery rate of ...
[32]
[PDF] Final Report on Life Testing of the Vapor Compression Distillation ...
The VCD/UPA is a phase-change water recovery technology which will reclaim water from urine and other ISS wastewaters. Two VCD/UPA's were tested, designated the ...Missing: ecological | Show results with:ecological
[33]
[PDF] ISS Water Recovery System, Vapor Compression Distillation ...
• Gas/liquid fluid flow occurs during waste water collection (urine, condensate,. Sabatier product water) and during the treatment process as required (urine.Missing: ecological life- support
[34]
Anaerobic Treatment of Organic Wastes from Controlled Ecological ...
Jul 1, 1992 · ... wastes from a Controlled Ecological Life Support System (CELSS). The anaerobic digester biologically breaks down the organic matter in the ...
[35]
Evaluation of an anaerobic digestion system for processing CELSS ...
Anaerobically processed waste as a nutrient source for higher plants in a controlled ecological life support system. SAE Technical Paper 932248 (1993). Google ...
[36]
[PDF] Synthetic Biology and Microbial Fuel Cells
The project aims to develop advanced MFCs for wastewater treatment and electricity, using synthetic biology to increase efficiency and convert CO2 into ...
[37]
https://ntrs.nasa.gov/api/citations/20190033326/downloads/20190033326.pdf
[38]
Appendix 10 Total Organic Carbon | Spacecraft Water Exposure ...
The upper limit of the standard for a TOC concentration was set at 3 mg/L, assuming that the TOC comes entirely from formaldehyde, which is the most toxic ...
[39]
Recovery of monovalent mineral salts from urine in controlled ...
Apr 1, 2020 · In controlled ecological life support system (CELSS), the water, oxygen, food and other life-support materials should be provided through ...
[40]
A five-stage treatment train for water recovery from urine and shower ...
Dec 1, 2020 · The core of the UPA is a Vapor Compression Distillation (VCD) unit to recover product water. It is particularly sensitive to organic fouling and ...Missing: ecological | Show results with:ecological
[41]
Recycling nutrients from organic waste for growing higher plants in ...
Recovery of monovalent mineral salts from urine in controlled ecological life support system by nanofiltration: feasibility study. Desalination, 479 (2020) ...
[42]
(PDF) Oxygen Loss in Biosphere 2 - ResearchGate
Aug 9, 2025 · O2 in Biosphere 2 decreased during the first 16 months of closure from the ambient 21% to 14%, enough to cause health problems in the human ...
[43]
None
### Summary of CELSS Monitoring and Control Technologies
[44]
None
### Summary of Mass Balance Model for CELSS Carbon Flow
[45]
AI-Driven Waste Management in Innovating Space Exploration - MDPI
The Controlled Ecological Life Support System (CELSS) exemplifies this integration, regenerating essential life-support materials for crew sustainability ( ...<|control11|><|separator|>
[46]
Hierarchically controlled ecological life support systems
In a CELSS, the limited degree of freedom, reduced size of the physical system, presence of multiple producers and consumers, tight technical and operational ...Missing: advantages | Show results with:advantages
[47]
[PDF] EARTH TO LUNAR - NASA Technical Reports Server (NTRS)
Jun 18, 1991 · The CELSS group examined the ideal phasing of biological organisms into a hybrid physical/chemical regenerative life support system as well as.
[48]
[PDF] N91 "1 845
The aim of Bios-3 was to establish a near complete air and water regenera- tion with considerable food production. It is in this context, that the Biosphere 2 ...
[49]
[PDF] Past, Present, and Future of Closed Human Life Support Ecosystems
Jul 20, 2017 · During the development of human space exploration, the idea of simulating the Earth's biosphere to provide human life support led to the ...
[50]
[PDF] 91-31791
Over the past two years, personnel of the Breadboard Project have concentrated on the construction and initial testing of a large biomass production chamber, ...Missing: 1980s experiments
[51]
Achieving and documenting closure in plant growth facilities
... CELSS Breadboard Project. The BPC is atmospherically sealed to a leak rate of approximately 5 percent of its total volume per 24 hours. This paper will ...
[52]
Veggie Plant Growth System Activated on International Space Station
May 16, 2014 · Another goal is to establish that the space lettuce is safe to eat. On the space station, the Veg-01 plants will grow for 28 days. Photographs ...
[53]
[PDF] Veggie Fact Sheet - NASA
Apr 25, 2019 · The Veggie concept is a simple, low-power sys- tem to grow fresh, nutritious food for our astro- nauts to supplement their diet and use as a ...
[54]
ESA ISS Science & System - Operations Status Report # 63 ... - ESA
This data is important for determining the reliability of using Arthrospira sp. in spacecraft biological life support systems in such projects as MELISSA (Micro ...
[55]
[PDF] Status of the International Space Station Regenerative ECLSS ...
It must recover a minimum of 85% of the water content in the specified wastewater stream. The UPA is packaged into 7 ORUs, which take up slightly more than ...
[56]
None
### Summary of Challenges in Microgravity for Hydroponics in CELSS on ISS (Up to Early 2020s)
[57]
[PDF] Advanced Life Support Research and Technology Development Metric
While the ALS Project supports current NASA missions as requested, most ALS technologies under development will provide technological solutions for missions ...Missing: 1990s- 2010s
[58]
Harnessing Synthetic Communities and Microbial Recycling of ...
By leveraging synthetic biology this study seeks to enhance the feasibility of long-term extraterrestrial habitation through sustainable resource management.Missing: papers consortia CELLS
[59]
Data-driven synthetic microbes for sustainable future - Nature
Jul 7, 2025 · Synthetic biology bridges this gap by enabling modifications to microbial genetic code, tailoring them for specific sustainable applications.Missing: NASA | Show results with:NASA
[60]
Synthetic biology for space exploration | npj Microgravity - Nature
Jul 12, 2025 · This paper explores key topics including resource utilization, life support systems, radiation protection, and human health
[61]
Overall Material Flow Scheme Design of Controlled Ecological Life ...
The controlled ecological life support system (CELSS) can achieve the simultaneous regeneration of oxygen, water, and food; improve the material closure of the ...
[62]
MELiSSA's future in space - ESA
Long duration human missions cannot be performed without regenerative life support systems like MELiSSA that will drastically cut the amount of logistics needed ...
[63]
Environmental Control and Life Support Systems Market Insights
Rating 4.0 (56) The market was valued at approximately $2.3 billion in 2022 and is projected to reach around $4.5 billion by 2030, growing at a CAGR of 8.9% during this period.
[64]
[PDF] In-Situ Resource Utilization Modeling of a Lunar Water Processing ...
This tool is currently being used to assess various interconnected ISRU technologies in water processing and oxygen extraction from lunar regolith; however,.
[65]
Oven Design for In‐Situ Thermal Extraction of Volatiles From Lunar ...
Jun 16, 2024 · The paper presents a realistic heating oven design for in-situ extraction of volatiles from lunar regolith Three factors controlling the ...
[66]
[PDF] NASA's Lunar Exploration Program Overview
NASA's Artemis program will lead humanity forward to the Moon and prepare us for the next giant leap, the exploration of Mars. It has been almost 50 years since ...Missing: CELSS | Show results with:CELSS
[67]
[PDF] Mars Surface Power Generation Challenges and Considerations
The impact of Martian dust storms on surface power will depend on severity and duration. Regional and global storms pose significant risk to surface power ...
[68]
[PDF] International Space Station as a Testbed for Exploration ...
Jul 25, 2024 · A particularly challenging area is the Environmental Control and Life Support System (ECLSS) that maintains a habitable and life-sustaining ...Missing: CELSS | Show results with:CELSS
[69]
Purdue and NASA scientists plant the seeds for lunar agriculture
Sep 10, 2024 · “Studying lunar gravity and radiation effects on plants is a critical step in developing bioregenerative life support for sustainable human ...
[70]
First Mars Crew Completes Yearlong Simulated Red Planet NASA ...
Jul 10, 2024 · The inaugural CHAPEA (Crew Health and Performance Exploration Analog) crew is “back on Earth” after walking out of their simulated Martian habitat.Missing: CELSS | Show results with:CELSS
[71]
NASA Announces CHAPEA Crew for Year-Long Mars Mission ...
Sep 5, 2025 · “The simulation will allow us to collect cognitive and physical performance data to give us more insight into the potential impacts of the ...Missing: 2023 CELSS
[72]
[PDF] Global Exploration Roadmap 2024
Sep 3, 2024 · The first step in the exploration plan is the Artemis campaign, which will enable human missions to the. Moon in a long-term, sustainable manner ...
[73]
[PDF] International Space Station United States Orbital Segment Oxygen ...
Water is electrolyzed into oxygen and hydrogen in the Hydrogen. ORU, which contains the electrolysis cell stack. Oxygen produced by the cell stack passes ...
[74]
[PDF] International Space Station Carbon Dioxide Removal Assembly (ISS ...
The existing International Space Station (ISS) Carbon. Dioxide Removal Assembly is part of the ISS air revitalization system, providing continuous COP removal.
[75]
NASA Achieves Water Recovery Milestone on International Space ...
Jun 20, 2023 · Station's Environmental Control and Life Support System (ECLSS) recently achieved the 98% water recovery goal.
[76]
Optimal operating parameters for advanced alkaline water electrolysis
Sep 30, 2022 · In practice electrolyzer systems typically have a nominal current density corresponding to an efficiency of 75–80% (based on the higher heating ...Missing: space | Show results with:space
[77]
Life support approaches for Mars missions - ResearchGate
Oct 9, 2025 · In addition, many components of physicochemical life support systems are heavy, highly energy-consuming and/or require high temperatures. ... ..
[78]
[PDF] blss: a contribution to future life support
compared to physico-chemical systems. At equal energy consumption for a BLSS and a physico- chemical system, the break-even point of mass is in the order of 7 ...
[79]
[PDF] Electrochemical Solutions for Advanced Life Support
Jul 11, 2019 · The Oxygen Generating Assembly (OGA) on-board the International Space Station (ISS) employs a polymer electrolyte membrane (PEM) water ...
[80]
The conceptual design of a hybrid life support system based on the ...
This report summarizes a trade study of different options of a bioregenerative Life Support System (LSS) and a subsequent conceptual design of a hybrid LSS.
[81]
Initial results from biosphere 2 - ScienceDirect.com
Biosphere 2 is the first man-made, soil-based, bioregenerative life support system to be developed and tested.
[82]
(PDF) Biosphere 2: A prototype project for a permanent and evolving ...
Aug 5, 2025 · It is open to information and energy flow. Biosphere 2 is designed to achieve a complex life-support system by the integration of seven areas or ...
[83]
Biosphere 2: Home
Biosphere 2 supports cutting-edge research in sustainability and ecosystem conservation, offering a unique platform to study Earth's complex systems and ...Visit Biosphere 2 · Biosphere 2 Board · About · Ocean Reef LabMissing: attempt | Show results with:attempt
[84]
Vertical Farming - Sky Greens
Mar 25, 2021 · Increases productivity – The production yield of Sky Greens Farm is 5 to 10 times more per unit area compared to other traditional farms ...
[85]
Future of Farming:How Vertical Farming Reshaping Agriculture
Feb 12, 2025 · By growing crops in stacked layers under controlled conditions, vertical farms use 95% less water, require minimal land, and can be established ...
[86]
GreenCap's self-sustaining greenhouses have adaptive climate ...
Nov 28, 2022 · GreenCap's system uses a closed-loop, zero-emission process, capturing CO2, controlling humidity and temperature, and reusing up to 70% of ...
[87]
Sustainable Desert Agriculture - AgriNext Conference
Oct 13, 2025 · Hydroponics, aeroponics, and aquaponics are revolutionizing food production by eliminating the need for soil and using up to 90% less water than ...Missing: 2020s | Show results with:2020s
[88]
Closing the Loop in Hydroponic Systems: From Global Sustainability ...
Closed-loop hydroponic systems significantly reduce water use per kg of lettuce by 6% in the UK and over 90% in Bangladesh and India, but this is offset by ...
[89]
Fighting Hunger Through Hydroponics in Lebanon
This project aims to build more hydroponics greenhouses and offer a practical and sustainable solution to address the food crisis in Lebanon.
[90]
Farming Solutions for Countries Facing Wars, Insecurity, and Natural ...
With hydroponics, crops can grow without needing any soil, a process that relies less on large tracts of land that could be inaccessible or dangerous in war ...
[91]
Vertical farming can save water and support food security
Jun 20, 2023 · Vertical farming offers a sustainable solution that uses 98% less water than traditional agriculture and can help support food security. Water ...
[92]
Vertical Farming – No Longer A Futuristic Concept - USDA ARS
Jan 10, 2025 · Vertical farms are being built in deserts, high-population urban areas, and other places that traditional open-field farming is not practical.<|separator|>