Diaphragmatic excursion
Diaphragmatic excursion refers to the craniocaudal displacement of the diaphragm, the primary muscle of respiration, during inhalation and exhalation, enabling changes in thoracic volume to facilitate breathing.[1] This movement is crucial for generating negative intrathoracic pressure during inspiration, allowing air to enter the lungs, and is typically assessed to evaluate respiratory muscle function.[2] The diaphragm is a dome-shaped musculotendinous structure that separates the thoracic and abdominal cavities, consisting of a central tendon and peripheral muscle fibers originating from the lower ribs, sternum, and lumbar vertebrae via the crura.[2] It is innervated bilaterally by the phrenic nerves, which arise from the C3-C5 cervical spinal roots, making it vulnerable to neurological insults affecting these pathways.[3] The right hemidiaphragm is generally larger and more curved due to the underlying liver, while the right is slightly higher than the left due to the liver beneath the right dome and the heart overlying the left.[2][4] Physiologically, during quiet tidal breathing, the diaphragm contracts and descends approximately 1.0–2.5 cm, increasing to 3.6–7.8 cm in adults during deep inspiration, with variations by sex (greater in men) and body position (greater in supine).[1] This excursion contributes to about 60–80% of inspiratory effort in healthy individuals, with similar excursion on both sides, though slight variations occur.[3] Normal motion is orthograde (downward on inspiration), and any reduction or reversal indicates potential dysfunction.[2] Excursion is measured noninvasively using techniques such as ultrasonography (M-mode for amplitude and velocity), fluoroscopy (sniff test for paradoxical motion), chest radiography, or MRI, with ultrasound being preferred for its portability and real-time capability.[1] In ultrasound assessment, acoustic windows like the liver (right) or spleen (left) are used to track dome displacement, providing values with high reproducibility.[2] Other methods include percussion for rough estimation or electromyography for nerve conduction.[3] Clinically, diaphragmatic excursion serves as a key indicator of respiratory health, with reduced or absent movement signaling conditions like unilateral or bilateral paralysis (often from phrenic nerve injury, trauma, or neuromuscular diseases), eventration (congenital thinning leading to elevation), or weakness in chronic obstructive pulmonary disease (COPD) due to hyperinflation.[3] It predicts outcomes in mechanical ventilation weaning, correlates with exercise capacity, and guides interventions such as plication surgery or phrenic nerve stimulation for symptomatic cases.[2] Paradoxical motion—upward during inspiration—is a hallmark of paralysis and can lead to respiratory failure if bilateral.[1]Anatomy and Physiology
Diaphragm Structure
The diaphragm is a dome-shaped musculotendinous partition that separates the thoracic cavity from the abdominal cavity, forming the floor of the thorax and the roof of the abdomen. It consists of a central aponeurotic tendon, which serves as the insertion point for the surrounding skeletal muscle fibers, and peripheral muscular components that radiate outward from this tendon. These muscle fibers are categorized into several parts: the costal part arising from the inner surfaces of the lower six ribs, the sternal part from slips of the xiphoid process of the sternum, the lumbar part from tendinous arches spanning the quadratus lumborum and psoas major muscles, and the crural part from the crura that originate on the anterior surfaces of the upper lumbar vertebrae (right crus from L1-L3, left from L1-L2). This composition enables the diaphragm's contractile properties while maintaining structural integrity during respiratory movements.[5] The origins of the diaphragmatic muscle fibers provide broad attachment to the surrounding skeletal framework, enhancing its mechanical efficiency. Specifically, the costal fibers interdigitate with those of the transversus abdominis muscle along the lower ribs (ribs 7 through 12), the sternal slips connect directly to the xiphoid process, and the crura and lumbar arches anchor to the lumbar vertebrae and the 12th rib via medial and lateral lumbocostal arches. All fibers converge to insert into the central tendon, a trefoil-shaped aponeurosis that is partially fused with the fibrous pericardium superiorly; notably, fibers from the right crus form a sling around the esophagus, contributing to its closure. This arrangement of attachments distributes tension evenly across the diaphragm, supporting its role in compartmental separation.[5] Key to the diaphragm's architecture are its apertures, which allow passage of vital structures while preserving overall stability essential for excursion. The major openings include the caval foramen at the level of the T8 vertebra, transmitting the inferior vena cava and occasionally branches of the right phrenic nerve; the esophageal hiatus at T10, through which the esophagus, anterior and posterior vagus trunks, and esophageal branches of the left gastric vessels pass; and the aortic hiatus at T12, accommodating the abdominal aorta, thoracic duct, and sometimes the azygos vein. Smaller minor apertures, such as those for the greater and lesser splanchnic nerves and the superior epigastric vessels via the foramina of Morgagni, further perforate the structure. These openings are reinforced by surrounding muscle and tendinous tissue, minimizing distortion during diaphragmatic contraction and ensuring excursion stability.[5] Innervation of the diaphragm is predominantly provided by the bilateral phrenic nerves, which arise from the anterior rami of spinal nerves C3, C4, and C5 (with C4 as the primary contributor) and descend through the thorax to penetrate the diaphragm near the central tendon. These nerves deliver both motor innervation to the muscular portions and sensory innervation to the central tendon, overlying pleura, and pericardium, with the right phrenic nerve supplying the right hemidiaphragm and the left supplying the left. This innervation supports coordinated diaphragmatic function.[5][6] The vascular supply to the diaphragm is multifaceted, ensuring adequate perfusion for its continuous activity. Arterial blood is delivered primarily by the superior phrenic arteries (branches of the thoracic aorta), inferior phrenic arteries (from the abdominal aorta), and musculophrenic arteries (terminal branches of the internal thoracic arteries), with additional contributions from the lower five posterior intercostal arteries and the subcostal arteries. These vessels form an anastomotic network around the diaphragmatic periphery and within its muscular layers, promoting redundancy and resilience. Venous drainage parallels the arterial supply, emptying into the azygos, hemiazygos, and internal thoracic veins.[5]Respiratory Mechanics
Diaphragmatic excursion refers to the vertical displacement of the diaphragm's dome, primarily downward during contraction, which is essential for altering thoracic cavity volume and facilitating ventilation. This movement is driven by the diaphragm's role as the principal muscle of inspiration, where its contraction flattens the dome, expanding the thoracic volume and drawing air into the lungs.[1] The contraction mechanism is initiated by stimulation of the phrenic nerve, originating from the C3-C5 spinal segments, which innervates the diaphragm's muscle fibers. Upon activation during inspiration, these fibers shorten, pulling the central tendon downward and causing the dome to descend, thereby increasing the vertical dimension of the thorax. This process is most pronounced in the costal and crural portions of the diaphragm, with the phrenic nerve providing exclusive motor supply to ensure coordinated activation.[6][7] Contraction of the diaphragm generates negative intrathoracic pressure, typically reaching -30 to -40 cmH₂O during forced inspiration, which creates a pressure gradient that promotes airflow into the alveoli. As the primary inspiratory muscle, the diaphragm synergizes with accessory muscles such as the external intercostals and scalenes to enhance chest wall expansion, while it relaxes passively during expiration to allow elastic recoil of the lungs and chest wall.[8][9] In physiological phases, the diaphragm contributes approximately 60-70% of the tidal volume during quiet breathing in the upright position, underscoring its dominance in effortless ventilation, and becomes even more critical for achieving larger volumes in deep breaths where excursion amplitude increases substantially.[10]Measurement Methods
Percussion and Palpation Techniques
Percussion and palpation represent fundamental bedside techniques for evaluating diaphragmatic excursion, allowing clinicians to assess the diaphragm's mobility without specialized equipment. These methods rely on the physical properties of sound transmission and tissue displacement during respiration to estimate the diaphragm's downward movement. The percussion technique involves identifying the level of the diaphragm by noting changes in percussion tone over the lower lung fields. With the patient in a seated or supine position and arms crossed anteriorly to facilitate access to the posterior chest, the examiner percusses downward along the midscapular line during quiet expiration until dullness is detected at the costophrenic angle, marking this level. The patient is then instructed to take a deep inspiration and hold it, after which percussion is repeated to identify the shift to resonance as the diaphragm descends; the vertical difference between the two levels constitutes the excursion, typically measuring 3-5 cm bilaterally in healthy adults.[11] This method highlights asymmetry if one side shows reduced movement. Palpation complements percussion by directly sensing diaphragmatic motion through tactile feedback. The examiner places the palms of both hands posteriorly on the lower hemithoraces near the diaphragm level, with thumbs together at the midline and parallel to the ribs, while the patient breathes deeply. Downward excursion is felt as the thumbs separate symmetrically during inspiration; this is particularly useful for unilateral assessments where one side may lag.[12] To perform the full procedure, the patient is first instructed to breathe normally for baseline observation, followed by deep breathing maneuvers repeated on both sides to compare symmetry and detect any paradoxical motion. These techniques offer advantages such as rapidity and accessibility at the bedside without requiring imaging, making them ideal for initial evaluations in resource-limited settings. However, they are inherently operator-dependent, with accuracy influenced by examiner experience, and may lack precision for detecting small excursions less than 1 cm. Historically, percussion for diaphragmatic assessment emerged as a traditional clinical tool in the early 20th century, building on 18th-century principles, and was commonly employed to identify paralysis through absent or reduced mobility.[13]Imaging-Based Assessments
Ultrasound is the most commonly employed imaging modality for assessing diaphragmatic excursion due to its non-invasive nature, lack of radiation, and portability. The technique typically involves using a low-frequency curved-array transducer (2-5 MHz) placed in a subcostal or intercostal acoustic window to visualize the diaphragmatic dome. In B-mode ultrasonography, the hyperechoic diaphragmatic line is identified for qualitative assessment of bilateral hemidiaphragm motion, while M-mode is preferred for quantitative measurement of excursion by capturing the vertical displacement of the dome from end-expiration to end-inspiration.[14][15][14] The procedure is performed with the patient in a supine or semi-recumbent position to optimize visualization, particularly for the right hemidiaphragm via the subcostal view in the mid-clavicular line; the left hemidiaphragm may require an intercostal approach to avoid interference from the heart. Measurements are obtained during tidal breathing for routine evaluation or deep inspiration/sniff maneuvers for maximal excursion, allowing separate quantification of right and left sides. This method demonstrates high reliability, with intraobserver intraclass correlation coefficients (ICC) often exceeding 0.9, supporting its reproducibility in clinical settings.[15][16][17] Fluoroscopy provides real-time radiographic imaging of diaphragmatic motion, enabling dynamic evaluation of excursion during respiration, often via the "sniff test" where the patient performs a sharp inspiratory sniff to accentuate motion. It is particularly useful for detecting paradoxical movements indicative of dysfunction but is limited by ionizing radiation exposure, making it less suitable for repeated use.[2][18][2] Magnetic resonance imaging (MRI) and computed tomography (CT) are less frequently used for motion assessment due to higher costs and limited availability for dynamic studies, though MRI excels in providing detailed anatomical visualization without radiation. Standard CT offers static positional evaluation, while emerging four-dimensional CT (4D-CT) reconstructs respiratory phases to quantify excursion, showing reduced motion in pathological cases compared to normals.[2][19][20] Compared to percussion-based methods, imaging techniques like ultrasound and fluoroscopy offer objective, quantifiable measurements in millimeters, enhancing precision for diagnostic purposes, though they require specialized equipment, operator expertise, and may face accessibility barriers in resource-limited settings.[18][15]Normal Values and Variations
Standard Excursion Ranges
In healthy adults, diaphragmatic excursion during tidal breathing typically measures 1 to 2 cm bilaterally, as established through M-mode ultrasonography in supine or seated positions. This range reflects normal quiet respiration, with mean values around 1.7 to 2.0 cm and lower limits of normality (LLN, 5th percentile) at approximately 0.9 cm for both hemidiaphragms across sexes.[21] For deep inspiration, excursion increases substantially to an overall range of 7 to 11 cm, with values varying by position, sex, and side. Reported values may vary by imaging modality, with ultrasound generally yielding lower excursions than fluoroscopy due to measurement location. In seated healthy adults, the right hemidiaphragm shows a mean excursion of 6.6 ± 1.3 cm in men (LLN 4.1 cm) and 5.4 ± 1.1 cm in women (LLN 3.3 cm), while the left hemidiaphragm averages 6.7 ± 1.3 cm in men (LLN 4.2 cm) and 5.4 ± 1.2 cm in women (LLN 3.2 cm). A slight left-side dominance is often observed during tidal breathing, though symmetry is expected in deep inspiration without pathology. During standard assessments in seated or supine positions, total excursion commonly falls within 3 to 5 cm, with bilateral symmetry expected in the absence of pathology.[21] These reference values derive primarily from ultrasound studies in large cohorts of healthy individuals (n > 100), such as 210 participants in a seminal 2009 analysis and 757 in a 2022 cross-sectional study, providing 95% confidence intervals for clinical benchmarking.[22]| Breathing Type | Position/Sex | Right Hemidiaphragm (Mean ± SD, cm) | Left Hemidiaphragm (Mean ± SD, cm) | LLN (cm) | Source |
|---|---|---|---|---|---|
| Tidal | Seated/Mixed | 1.8 ± 0.5 | 1.9 ± 0.5 | 0.9 | Boussuges et al. (2021)[21] |
| Deep | Seated/Men | 6.6 ± 1.3 | 6.7 ± 1.3 | 4.1 (R), 4.2 (L) | Boussuges et al. (2021)[21] |
| Deep | Seated/Women | 5.4 ± 1.1 | 5.4 ± 1.2 | 3.3 (R), 3.2 (L) | Boussuges et al. (2021)[21] |