Fact-checked by Grok 2 weeks ago

Generation Rescue

Generation Rescue was an American nonprofit organization founded in 2005 by parents J.B. Handley and Lisa Handley to assist families of children with autism spectrum disorders through guidance on biomedical treatments aimed at recovery.^[1]^[2] The group positioned autism not as an inevitable genetic condition but as a recoverable disorder primarily triggered by environmental exposures, including vaccines and toxins, advocating interventions such as chelation therapy for heavy metal detoxification and dietary changes.^[2] It offered programs like mentor family networks, financial grants for treatments, and educational summits featuring clinicians promoting these approaches, claiming to support over 25,000 families nationwide.^[3]^[4] Actress Jenny McCarthy, whose son was diagnosed with autism, joined the board and amplified the organization's message through books and media appearances, emphasizing parental anecdotes of improvement via unorthodox therapies over mainstream behavioral interventions.^[1] Generation Rescue conducted informal surveys, such as a 2007 telephone poll estimating autism prevalence and linking it to vaccination rates across states, though these lacked rigorous controls and were critiqued for methodological flaws.^[2] The organization faced criticism for promoting causal claims about vaccines and autism unsupported by large-scale epidemiological studies, which have consistently found no such association after adjusting for diagnostic changes and genetic factors; nonetheless, it prioritized first-hand parent reports and alternative research challenging institutional consensus on autism's etiology.^[5] By 2019, Generation Rescue wound down operations, with its website deactivated and resources transitioning to affiliated groups like TACA, though social media channels remained sporadically active.^[6]

Founding and History

Establishment and Early Years

Generation Rescue was established in 2005 by J.B. Handley and his wife Lisa Handley as a nonprofit organization dedicated to supporting families affected by autism through parent-directed biomedical recovery approaches.^[7]^[8] The initiative emerged from the Handleys' experiences following the autism diagnoses of their two sons, prompting a quest for interventions beyond conventional therapies.^[9]^[10] The founders' motivation centered on the conviction that autism spectrum disorders often stem from environmental exposures rather than exclusively genetic predispositions, a view shaped by their research into potential triggers and reports of children improving via targeted treatments.^[9] This perspective led to the creation of a grassroots network, initially comprising around 150 volunteer "Rescue Angels" who connected parents with shared experiences and protocols.^[11] In its formative phase, the organization emphasized connecting families with accounts of "recovered" children, facilitating the exchange of biomedical strategies such as dietary changes, supplementation, and chelation therapy aimed at detoxifying heavy metals presumed to contribute to symptoms.^[9] These efforts sought to democratize access to emerging recovery narratives, positioning parents as central decision-makers in treatment pursuits amid rising U.S. autism diagnosis rates, which had climbed from approximately 1 in 150 children in 2000 to higher figures by the mid-2000s.

Key Founders and Leadership

J.B. Handley and his wife Lisa Handley co-founded Generation Rescue in 2005, driven by their son's autism diagnosis and a belief in environmental factors as a primary cause amenable to biomedical intervention.^[9]^[7] J.B. Handley, a private equity investor with over 30 years of experience including as managing director and co-founder of Swander Pace Capital—a firm managing more than $1.5 billion—served as the organization's chairman, steering its focus on parent-led recovery protocols such as chelation therapy to remove heavy metals.^[7]^[12] Lisa Handley contributed as a co-founder and director, emphasizing grassroots, family-centered support networks drawn from personal experience.^[13]^[7] Actress and author Jenny McCarthy joined the board around 2008 following her own son's autism diagnosis, eventually assuming the role of president and becoming the organization's most visible spokesperson.^[13]^[14] McCarthy advocated for Generation Rescue's biomedical approach through her books, including Louder Than Words (2007), and television appearances, positioning the group as a resource for parents seeking alternatives to conventional therapies.^[5]^[15] Early leadership also included board members like Deirdre Imus and Katie Wright, parents who reinforced the organization's commitment to treatment-focused research over genetic determinism.^[16] This parent-driven structure prioritized empirical recovery stories and environmental causation hypotheses, with Handley family members maintaining oversight amid evolving board composition.^[17]

Organizational Evolution

By the late 2000s, Generation Rescue had expanded its structure to incorporate a network of over 450 mentor families alongside partnerships with clinicians and researchers from multiple countries, facilitating a global dimension to its parent-led advocacy model.^[18] In 2019, amid signs of waning organizational momentum, the group initiated rebranding initiatives that pivoted its public messaging from autism-specific recovery toward encompassing wider themes of health empowerment and toxin avoidance. This included suspending its primary website in May 2019, replacing it with a placeholder page signaling impending relaunches and broader programmatic adjustments.^[6]^[19]^[20] Post-2010s, the organization scaled back centralized operations, with formal activities diminishing while sustaining visibility and limited engagement via active social media channels and targeted grant support mechanisms as observed into 2025.^[21]^[22]

Mission and Core Principles

Advocacy for Biomedical Recovery

Generation Rescue positioned autism spectrum disorders as recoverable conditions through biomedical interventions targeting physiological imbalances, rather than as permanent neurodevelopmental states requiring only behavioral management. The organization emphasized protocols that address gastrointestinal disturbances, immune system dysregulation, and detoxification of environmental toxins, asserting these could reverse symptoms and restore typical functioning in affected children. This advocacy stemmed from parent-led observations of improvements following such treatments, including dietary exclusions of gluten and casein to repair gut permeability, antimicrobial therapies for dysbiosis, and supplements to modulate inflammation and oxidative stress.^[23] Central to their stance was the rejection of autism's prognosis as inevitably lifelong or predominantly genetic, with founders like J.B. Handley arguing that early biomedical application could prevent entrenched neurological deficits. They contended that withholding timely medical access for young children—ideally under age five—allowed reversible metabolic disruptions to solidify, based on surveys of over 1,000 parents reporting recovery rates of up to 20% via these methods. Generation Rescue highlighted anecdotal cases where children regained speech, social skills, and cognitive abilities after interventions, framing autism not as an intrinsic brain wiring but as a treatable cascade of bodily insults amenable to correction.^[24]^[25] Influenced by the Defeat Autism Now (DAN!) framework, which Generation Rescue endorsed and extended, their approach prioritized individualized biomedical testing—such as for heavy metal burdens or yeast overgrowth—followed by tailored detoxification, including chelation therapy to remove mercury or lead presumed to impair neural development. Handley, a co-founder, publicly claimed his son's autism symptoms reversed through chelation, exemplifying their belief in environmental triggers yielding to physiological restoration over time. While these claims relied heavily on uncontrolled parent reports rather than randomized trials, the organization urged immediate, aggressive treatment to exploit neuroplasticity windows in early childhood, positioning biomedical recovery as an ethical imperative against passive acceptance of disability.^[2]^[26]

Parent-Led Support Model

Generation Rescue's Parent-Led Support Model centers on a decentralized, peer-driven framework in which parents of children diagnosed with autism spectrum disorder share practical guidance drawn from their own experiences with biomedical interventions, bypassing reliance on institutional medical hierarchies that often prioritize behavioral therapies over potential causal treatments.^[3] This approach positions families as active agents in pursuing recovery, fostering direct connections between "veteran" parents who report substantial progress in their children and newcomers navigating diagnosis.^[27] Key to the model is the deployment of over 450 mentor families worldwide, operating as "Rescue Angels"—volunteers whose children have achieved notable developmental gains post-treatment, offering tailored advice on options like detoxification protocols and nutritional adjustments.^[18] These mentors emphasize parental autonomy in evaluating and implementing strategies, reflecting skepticism toward mainstream pediatric guidelines that dismiss environmental triggers and advocate lifelong accommodation rather than reversal.^[28]^[29] By prioritizing narratives of milestone attainment—such as regained speech or social engagement after interventions—the model instills hope against diagnostic prognoses framing autism as immutable, encouraging parents to challenge gatekept expertise from bodies like the American Academy of Pediatrics, which Generation Rescue views as unduly influenced by pharmaceutical interests over empirical parental outcomes.^[30] This grassroots ethos underscores a belief in parental intuition as a counterweight to top-down authority, promoting community-sourced resilience over passive acceptance of spectrum permanence.^[31]

Emphasis on Environmental Factors

Generation Rescue maintains that the sharp rise in autism spectrum disorder (ASD) prevalence—from roughly 1 in 10,000 children in the late 1970s and early 1980s to 1 in 36 by 2020, as reported by the U.S. Centers for Disease Control and Prevention (CDC)—indicates an environmental epidemic rather than mere expansions in diagnostic criteria or genetic inevitability.^[32]^[33] The organization attributes this surge to post-1980s alterations in environmental exposures, including the tripling of the U.S. childhood vaccine schedule from three doses at birth in 1983 to over 30 by age six in subsequent decades, which temporally aligns with accelerated ASD diagnosis rates.^[9]^[34] Central to this perspective is a focus on causal pathways evident in the proximity between early-life exposures and acute neurodevelopmental regressions observed in many affected children, often occurring between 12 and 18 months of age—a pattern Generation Rescue contrasts with diffuse genetic polygenic risk models, which fail to account for the population-level incidence explosion without invoking unverified interaction effects.^[9] Co-founder J.B. Handley, whose son regressed post-vaccination, has articulated this view, asserting that no studies conclusively disprove environmental triggers in individual cases and that epidemic-scale shifts demand scrutiny of modifiable external variables over static heritability estimates, which twin studies peg at 60-90% but do not explain temporal trends.^[9]^[35] The group challenges institutional emphases in academia and public health agencies, which often prioritize genetic research funding—evidenced by billions allocated to genomics since the 2000s—while deprioritizing epidemiological probes into industrial outputs, pharmaceutical regimens, and dietary shifts concurrent with ASD upticks.^[9] Generation Rescue contends this allocation reflects systemic reluctance to implicate profitable interventions, urging instead mechanistic investigations into toxin burdens and immune activations that correlate with vulnerability windows in infant development, independent of rare monogenic variants identified in under 1% of cases.^[35]^[9]

Programs and Initiatives

Mentor Family Network

The Mentor Family Network, operating under the banner of "Rescue Angels," comprises a volunteer cadre of parents whose children with autism spectrum disorders exhibited significant improvements or symptom reversal following biomedical interventions, providing personalized guidance to families facing recent diagnoses.^[3] Established concurrently with Generation Rescue's founding in 2005 alongside an initial cohort of 150 such parent volunteers, the network emphasizes peer-to-peer mentoring on the practical application of treatments including gluten- and casein-free diets, nutritional supplementation, and detoxification protocols.^[36] These mentors, drawn from families reporting recoveries attributed to environmental factor mitigation rather than genetic inevitability, offer one-on-one support tailored to individual circumstances, such as navigating supplement regimens or monitoring dietary adherence for behavioral changes.^[3] By the mid-2010s, the network had expanded to over 1,300 volunteer mentors operating in 48 countries, facilitating global access to this support model without geographic constraints.^[37] Mentors assist with connecting families to sympathetic clinicians versed in biomedical approaches, prioritizing actionable steps over theoretical discussions, though efficacy relies on anecdotal participant feedback rather than controlled trials.^[38] Thousands of families reportedly received assistance through this system by that period, with outcomes gauged via self-reported metrics like enhanced communication skills or reduced sensory sensitivities in children, underscoring the organization's parent-led ethos amid limited mainstream validation of the underlying protocols.^[3]^[38]

Financial and Resource Assistance

Generation Rescue's Rescue Family Grant program, initiated in June 2009, offered direct financial aid to families facing economic barriers to biomedical autism treatments.^[39] The grants targeted initial recovery efforts, covering expenses such as two consultations with physicians specializing in autism biomedical protocols, a 90-day supply of vitamins, minerals, and essential supplements, and guidance on dietary modifications to support detoxification and nutritional balance.^[39] This assistance was positioned to address treatments often excluded from private insurance or public programs, enabling families to pursue interventions grounded in the organization's environmental causation hypothesis.^[40] The program emphasized early intervention to maximize potential recovery outcomes, with grants designed for families new to biomedical approaches who demonstrated financial need through application processes.^[3] Recipients gained access to products and services via partnerships with sponsoring entities, including supplement providers and treatment vendors, which facilitated discounted or subsidized acquisition of diagnostics, therapies like auditory integration, and ongoing supportive items.^[41] Such collaborations extended the reach of aid by leveraging corporate donations for in-kind contributions, reducing out-of-pocket costs for therapies aimed at addressing symptoms attributed to toxin exposure.^[1] Funding for these grants derived primarily from individual and corporate donations to Generation Rescue, with organizational financial reports indicating revenues in the range of hundreds of thousands to over one million dollars annually during peak operations, a portion of which supported family assistance initiatives alongside advocacy and research.^[36] While specific breakdowns for grant allocations versus other expenditures were not publicly detailed in audited statements, the program's structure prioritized direct aid to sustain treatment momentum for affected children.^[3] The initiative provided hope and tangible resources to thousands of families, underscoring the nonprofit's commitment to practical recovery support amid debates over autism etiology.^[42]

Educational Resources and Summits

Generation Rescue organized the Autism Education Summits, annual events aimed at educating parents and professionals on strategies for autism recovery through biomedical and therapeutic approaches.^[43] These summits featured presentations from medical practitioners and advocates, such as Dr. Amy Myers on autoimmune aspects of autism and Dr. Will Cole on functional medicine interventions, with sessions recorded and shared publicly.^[44] Events occurred in locations including Dallas, Texas, with documented gatherings in 2017 and 2018 that included celebrity participants like Jenny McCarthy and Donnie Wahlberg discussing parental experiences.^[45] ^[46] The summits emphasized practical tools for families, such as accessing grants for treatments and networking with mentors, while highlighting recovery stories from participants in Generation Rescue's programs.^[47] By partnering with conferences like AutismOne, the organization extended its educational reach to broader audiences seeking novel therapies beyond standard behavioral interventions.^[3] These events, active through the 2010s, sought to equip attendees with knowledge to pursue individualized protocols, countering reliance on conventional medical diagnostics.^[48] Complementing the summits, Generation Rescue disseminated online educational materials via its YouTube channel, including video series on autism symptoms, diagnostic testing, and implementation of recovery protocols.^[49] The "Treating Autism Series" provided guidance on biomedical options, while summit recaps and standalone videos offered accessible overviews for self-directed learning by parents.^[50] These resources, updated periodically through at least 2018, encouraged families to explore environmental and physiological factors in autism management independently of institutional healthcare pathways.^[51] Toolkits and digital downloads, distributed at summits or via partnerships, focused on symptom tracking and protocol starters, promoting parental empowerment in navigating treatment options.^[52] This approach underscored Generation Rescue's model of fostering informed advocacy, enabling families to challenge diagnostic limitations through evidence-based self-education drawn from practitioner insights and peer experiences.^[53]

Views on Autism Causes

Hypothesis of Environmental Toxins

Generation Rescue posits that autism spectrum disorders arise primarily from the overload of environmental toxins, including heavy metals like mercury and chemicals such as pesticides, on the body's detoxification systems, particularly in genetically susceptible children whose impaired metabolic pathways fail to eliminate these substances effectively. This cumulative toxic burden, according to the organization, disrupts neurological development and manifests as autism symptoms, rather than autism being a static genetic condition. The hypothesis draws on observed correlations between toxin retention and symptom severity, such as lower mercury concentrations in hair samples from autistic children (e.g., 0.47 ppm versus 3.63 ppm in neurotypical controls in a 2003 study of infant haircuts), which proponents interpret as evidence of poor excretion and intracellular accumulation rather than reduced exposure. Similar patterns in nail samples have been cited to suggest that vulnerable individuals retain pollutants like pesticides and industrial chemicals, exacerbating oxidative stress and inflammation in the brain.^[54] From a causal perspective, Generation Rescue emphasizes the incompatibility of rapidly rising autism prevalence— from roughly 1 in 10,000 in the early 1980s to 1 in 36 U.S. children born in 2012, per CDC surveillance data—with predominantly genetic explanations, as population-level genetic shifts occur too slowly to account for such an "epidemic." This reasoning prioritizes environmental triggers, urging investigation into post-1980s increases in toxin exposures from sources like air pollution and agricultural chemicals, independent of vaccination schedules. Mainstream epidemiological analyses attribute much of the rise to diagnostic expansion and awareness, yet the organization's view aligns with calls for toxin-focused research amid ongoing debates over understudied gene-environment interactions. Generation Rescue, through its founder J.B. Handley, contended that thimerosal, an ethylmercury-based preservative used in multi-dose vials of several childhood vaccines until its removal from most U.S. routine infant vaccines by 2001, induced neurotoxicity leading to autism spectrum disorders in susceptible children.^[9] Handley argued that the cumulative mercury exposure from the expanded vaccine schedule in the late 1980s and 1990s—reaching up to 237 micrograms by 18 months of age—mirrored symptoms of mercury poisoning, including social withdrawal and repetitive behaviors observed in autism.^[55] Handley cited proprietary surveys conducted by Generation Rescue, including a 2007 telephone poll of over 9,000 U.S. households with children aged 4-17, which reported autism prevalence at 0.7% among fully unvaccinated children compared to 1.7% among fully vaccinated ones, suggesting a dose-response relationship with vaccination status.^[55] A follow-up analysis claimed vaccinated children faced 2.48 times higher odds of autism diagnosis than unvaccinated peers, positioning these findings as preliminary evidence of a vaccination-autism correlation absent in mainstream cohort studies.^[55] The organization invoked parent-reported temporal associations, where autism regressions often clustered within days to weeks following vaccination milestones, such as the 12-18 month schedule including DTaP, Hib, and hepatitis B shots containing thimerosal pre-2001.^[9] Supporting this, Generation Rescue referenced animal models, including a 2005 study on infant macaques exposed to thimerosal doses mimicking human vaccine schedules, which demonstrated ethylmercury accumulation in the brain and disruption of neuronal growth, akin to mercury-induced neurodevelopmental harm.^[56] While the 2004 Institute of Medicine report rejected a causal link between thimerosal-containing vaccines and autism based on epidemiological data from Denmark and the U.S., Generation Rescue emphasized that such studies inadequately addressed cumulative antigen or mercury loads across the full schedule or direct vaccinated-unvaccinated comparisons.^[57] They further noted potential underascertainment in systems like VAERS, where a 2010 Harvard Pilgrim analysis estimated fewer than 1% of vaccine adverse events are reported, possibly obscuring rare neurotoxic signals from synergistic exposures.^[58]^[57]

Contrast with Mainstream Genetic Explanations

Generation Rescue posits that mainstream genetic explanations for autism spectrum disorder (ASD) inadequately account for the observed rapid rise in prevalence, which increased from roughly 1 in 2,000 children in the early 1980s to 1 in 36 by 2020 per Centers for Disease Control and Prevention surveillance data. Proponents, including co-founder J.B. Handley, contend that genetic factors evolve too slowly across generations to drive such an "epidemic," rejecting diagnostic expansion or awareness as sufficient explanations and instead emphasizing unidentified environmental triggers capable of producing population-level shifts.^[9] This view prioritizes causal mechanisms with temporal alignment to incidence trends over polygenic heritability models, which, despite identifying over 100 associated loci, explain only a fraction of cases and fail to predict the scale of recent increases.^[35] A key evidential gap highlighted is the prevalence of developmental regression in ASD, occurring in approximately 20-33% of cases, where children exhibit typical milestones before abruptly losing skills, often around 18-24 months.^[59]^[60] Generation Rescue argues this pattern of acquired loss post-normal development contradicts innate genetic models, which would manifest deficits from birth rather than sudden regressions suggestive of external insults; mainstream genetic paradigms, focused on de novo mutations or heritability estimates exceeding 80%, offer no mechanism for such postnatal reversals without invoking non-genetic precipitants.^[61] Twin studies further underscore discordance in monozygotic pairs, with ASD concordance rates ranging from 60-90% rather than 100%, indicating that shared genetics alone do not determine outcomes and implying environmental modulators or triggers.^[62]^[63] Generation Rescue leverages this to challenge high heritability claims, asserting that the incomplete penetrance—evident in studies showing shared environmental influences on symptom severity—supports a multifactorial model where verifiable toxins interact with susceptibility rather than genetics as the predominant cause; despite mainstream attributions to gene-environment interplay, no specific genes have been isolated to explain the discordance or epidemic timing, leaving room for alternative causal realism.^[64]^[65]

Advocacy Efforts

Media Campaigns and Public Outreach

In 2005, Generation Rescue initiated a national media campaign featuring radio advertisements broadcast across the United States, emphasizing that autism and related disorders are recoverable through biomedical interventions and attributing them primarily to environmental factors such as toxins rather than genetic inevitability. The campaign, which continued through early 2007, aimed to challenge prevailing medical narratives by promoting parent-led recovery stories and calling for increased scrutiny of potential environmental triggers.^[66] A key component of the organization's outreach involved publicizing survey data to question vaccine safety. In June 2007, Generation Rescue released findings from a telephone survey of parents of approximately 9,000 boys aged 4 to 17, conducted by a market research firm, which reported that fully vaccinated children were 2.48 times more likely to have autism or other speech problems compared to unvaccinated peers. The organization disseminated these results through press releases and media statements, positioning them as evidence of a vaccine-autism link and urging policy changes to reduce childhood vaccination schedules or improve vaccine testing. Critics noted methodological limitations, including self-reported diagnoses and potential selection bias in respondent recruitment via homeschooling networks, but Generation Rescue maintained the survey highlighted overlooked risks.^[55] In September 2007, the group placed a full-page advertisement in USA Today, drawing parallels between rising vaccination rates since the 1980s and the increase in autism diagnoses, implying a correlative relationship warranting further investigation. Complementing this, in 2009, Generation Rescue launched the "14 Studies Later" campaign, which critiqued 14 large-scale epidemiological studies cited by health authorities as evidence against a vaccine-autism connection; the initiative argued these studies suffered from inadequate sample sizes, failure to account for regression to the mean, or confounding variables like diagnostic changes. A dedicated website hosted detailed analyses of each study, alongside calls for independent replication, to foster public doubt in mainstream assurances of vaccine safety. Organization representatives further extended outreach through television appearances on programs like The Oprah Winfrey Show, where they shared anecdotal recovery narratives and advocated for parental empowerment in treatment decisions over reliance on genetic explanations.^[67]^[68]^[69]

Celebrity Endorsements and Partnerships

Jenny McCarthy served as president of Generation Rescue's board of directors, leveraging her celebrity status as an actress and author to promote the organization's mission. In her 2007 book Louder Than Words: A Mother's Journey in Healing Autism, McCarthy detailed her son's autism diagnosis and recovery through biomedical interventions, attributing it to environmental factors including vaccines, which aligned with Generation Rescue's advocacy. Her board role, announced alongside other members like Deirdre Imus and Katie Wright, focused on directing resources toward treatment-based research for autism and ADHD.^[16]^[36] McCarthy's then-partner, actor Jim Carrey, collaborated on high-profile events to boost visibility and fundraising. In April 2008, Carrey endorsed Generation Rescue by signing a full-page advertisement in major newspapers calling for safer vaccines. Together, they co-hosted a July 2008 autism fundraiser attended by celebrities including Britney Spears, raising awareness for the organization's environmental toxin hypothesis. Carrey also joined McCarthy at the June 2008 Green Our Vaccines march in Washington, D.C., sponsored in part by Generation Rescue, which drew thousands to demand changes in vaccine policy.^[70]^[71]^[72] Generation Rescue partnered with World Wrestling Entertainment (WWE) for promotional tie-ins, including a 2008 collaboration for the Saturday Night's Main Event broadcast on August 2. WWE promoted the organization through on-air segments featuring McCarthy, encouraging donations and autism awareness while highlighting Generation Rescue's resources for families. This alliance extended WWE's platform to amplify the group's message, with McCarthy expressing enthusiasm for the partnership in WWE media statements.^[18]^[73]

Promoted Research and Surveys

Generation Rescue commissioned a telephone survey in 2007 through the polling firm SurveyUSA, targeting parents of roughly 17,000 children aged 4–17 across nine counties in California and Oregon. The survey relied on parent reports of vaccination history and medical diagnoses, comparing rates of neurodevelopmental disorders between vaccinated and unvaccinated children. Findings showed vaccinated boys were 61% more likely to have autism, 224% more likely to have ADHD, and overall 2.5 times more likely to have private diagnoses of neurological disorders than unvaccinated boys in the same age group.^[55] The organization advocated for independent, non-government-funded research on biomedical interventions targeting autism symptoms, such as nutritional supplements and detoxification protocols, while critiquing the Centers for Disease Control and Prevention (CDC) for methodological flaws in vaccine safety studies. Co-founder J.B. Handley argued that CDC analyses, including early thimerosal data reviews, selectively excluded subgroups to minimize apparent risks and avoided direct comparisons of fully vaccinated versus unvaccinated cohorts.^[9] Generation Rescue promoted parent-conducted and reported surveys as legitimate sources of empirical data on treatment efficacy, citing thousands of anecdotal accounts of symptom regression reversal through biomedical approaches as evidence warranting further investigation over stringent randomized trial standards, which they viewed as impractical for rare conditions.^[9]

Controversies and Criticisms

Promotion of Specific Treatments and Products

Generation Rescue endorsed chelation therapy as a core treatment for autism, viewing it as a means to remove heavy metals such as mercury believed to underlie the condition, despite the absence of scientific evidence linking such toxins to autism causation or demonstrating chelation's efficacy for autism spectrum disorder (ASD).^[74]^[75] The organization, co-founded by J.B. Handley, highlighted personal anecdotes of improvement, including Handley's report that his son showed substantial gains in speech and behavior after receiving the chelating agent DMSA every other day starting in 2003, alongside dietary changes and supplements.^[74]^[76] However, chelation is approved by the U.S. Food and Drug Administration (FDA) solely for treating confirmed heavy metal poisoning, not ASD, and systematic reviews have found no reliable benefits while noting risks including hypocalcemia, renal toxicity, and rare fatalities, such as the 2005 death of a five-year-old boy during chelation for autism and two additional pediatric cases linked to EDTA-induced hypocalcemia.^[77]^[75]^[78] The group also promoted hyperbaric oxygen therapy (HBOT) for enhancing cerebral oxygenation and reducing inflammation in autistic children, often featuring portable chambers from manufacturers affiliated with board members or supporters.^[14] Generation Rescue shared stories of children gaining verbal abilities after HBOT sessions, as in a 2014 endorsement of an OxyHealth chamber trial, though randomized controlled trials have shown no significant improvements in core ASD symptoms.^[79]^[80] HBOT lacks FDA approval for autism treatment outside investigational use, with potential adverse effects including barotrauma and oxygen toxicity.^[77] Nutritional supplements, including vitamins, minerals, and cofactors like DMG and B12, were routinely recommended by Generation Rescue-affiliated physicians such as Jerry Kartzinel, who advised starting with basic regimens to support detoxification and neurological function.^[81] These interventions were positioned as accessible first steps in biomedical protocols, with claims of behavioral enhancements in some children, though empirical data on their specific efficacy for ASD remains limited and inconclusive, often relying on parental surveys rather than controlled studies.^[82] The promotion of such products, sometimes tied to commercial interests of associates, occurred amid broader concerns over unproven therapies' safety and the FDA's warnings against over-the-counter chelators marketed for autism.^[14]^[83]

Conflicts of Interest with Leadership

J.B. Handley, co-founder of Generation Rescue, personally advocated for biomedical treatments such as methyl B12 supplementation and chelation therapy, drawing from his family's implementation of these interventions for his son diagnosed with autism in the early 2000s, though no evidence indicates he held direct ownership in related commercial ventures.^[74] Handley received no reported compensation from the organization as a director, per IRS Form 990 filings.^[36] However, other leadership figures exhibited clearer financial interconnections with promoted products. Former executive director Candace McDonald earned over $100,000 annually in salary from 2008 to 2018, plus additional consulting fees exceeding $100,000 per year and rent payments (e.g., $27,225 in 2015) routed through her LLC, Candyland Brands, which co-owned revitaPOP—a line of B12 lollipops marketed for autism and sold directly via Generation Rescue's online store until its discontinuation around 2017.^[14] Past president Stan Kurtz co-founded revitaPOP, creating undisclosed overlap between board oversight and product endorsement.^[14] Board member Samir Patel, serving from 2015 to 2016, was president of OxyHealth, the manufacturer of hyperbaric oxygen chambers costing over $20,000 each, which Generation Rescue actively promoted as a treatment for autism without disclosing Patel's affiliation.^[14] These ties extended to sponsorships, such as from IonCleanse for detox foot baths, and grants directing families to practitioners recommending Generation Rescue-endorsed supplements and therapies. Critics, citing tax records and promotional materials, argued such arrangements incentivized a toxin-centric narrative to drive product sales, potentially prioritizing financial gain over evidence-based scrutiny.^[14] ^[84] The organization faced calls for enhanced disclosure of these relationships, though no formal regulatory actions or detailed public responses from leadership were documented.^[14]

Failed Projects and Legal Issues

Generation Rescue maintained an affiliation with the Center for Advanced Medicine, operated by Dr. Rashid Buttar in North Carolina, referring patients for alternative autism treatments including chelation therapy.^[85] The organization discontinued its involvement with Buttar's clinic around 2010, though the specific reasons were not publicly detailed in associated records.^[85] Buttar's practice faced significant regulatory scrutiny from the North Carolina Board of Medical Examiners, which in 2008 restricted his license following complaints over unproven and potentially unsafe interventions for autism, such as high-dose chelation and off-label use of medications lacking empirical support for efficacy in treating the condition.^[86] A notable incident highlighting these challenges involved Generation Rescue's then-president Stan Kurtz escorting patient Desiree Jennings to Buttar's clinic in 2009 for treatment related to alleged vaccine injury symptoms.^[87] When Jennings' condition did not improve and symptoms recurred, Buttar demanded $32,000 in unpaid fees, prompting Generation Rescue to dispute the claims and label her recovery as fraudulent, leading to a public fallout and non-payment.^[87] This episode underscored efficacy doubts surrounding the clinic's protocols, contributing to the broader termination of Generation Rescue's referrals to such facilities amid growing concerns over patient safety and lack of rigorous evidence.^[88] Post these developments, Generation Rescue experienced internal shifts, including leadership transitions; founder J.B. Handley reduced his role to pursue other advocacy efforts, while the organization scaled back direct endorsements of specific clinical partnerships.^[89] No major lawsuits directly targeted Generation Rescue for advertising or misinformation claims were documented, though its promotion of unverified treatments drew indirect legal attention through patient cases in federal vaccine courts, where environmental causation arguments, including those aligned with the group's views, were routinely rejected on evidentiary grounds.^[90]

Reception and Impact

Support from Affected Families

Many parents of children with autism reported positive experiences with Generation Rescue's resources, crediting the organization with providing actionable guidance on biomedical interventions such as gluten-free casein-free diets, vitamin supplementation, and detoxification methods that they associated with improvements in their children's symptoms. For instance, families described gains in speech, eye contact, and behavioral regulation following these protocols, often attributing the progress to the structured support and parent-led advice networks facilitated by the group.^[25]^[91] The organization's online forums and mentorship programs helped build communities where parents exchanged experiences, reducing isolation and empowering families to advocate for personalized treatment plans beyond conventional therapies. Reviewers frequently praised Generation Rescue for offering hope and practical tools during challenging diagnoses, with one parent noting the value of connecting with others who had navigated similar paths to perceived recovery.^[3] On review platform GreatNonprofits, Generation Rescue garnered an average rating of 4 out of 4 stars from 75 family-submitted reviews as of its active period, with testimonials emphasizing the nonprofit's role in granting funds for treatments and fostering resilience among affected households. Parents highlighted how these elements encouraged sustained commitment to alternative care, viewing the organization as a vital resource for challenging the prevailing view of autism as irreversible.^[3]

Scientific Community Responses

The scientific consensus, as articulated by bodies such as the Institute of Medicine (now National Academy of Medicine), has consistently rejected claims of a causal link between vaccines and autism spectrum disorder (ASD), citing epidemiological studies involving large cohorts that found no association with MMR vaccines, thimerosal, or vaccination timing.^[92]^[93] The 2004 IOM report, based on reviews of clinical and population data, concluded that evidence favors rejection of a causal relationship, emphasizing biological implausibility and lack of supporting mechanisms.^[94] Subsequent analyses, including those from the CDC, have reinforced this in studies tracking over a million children, showing no increased ASD risk from vaccine exposure.^[95] Critiques of Generation Rescue's promoted treatments, particularly chelation therapy for purported heavy metal detoxification, highlight significant safety risks and absence of efficacy evidence for ASD. The FDA issued warnings in 2010 against over-the-counter chelation products marketed for autism, noting they are unapproved, potentially causing kidney damage, nutrient depletion, and death, as seen in a 2005 case of a child fatality from EDTA administration.^[77]^[96] Peer-reviewed reviews underscore that chelation lacks randomized controlled trials demonstrating benefits for ASD symptoms, with risks outweighing unproven gains absent confirmed metal poisoning.^[97] Generation Rescue's surveys, such as the 2009 parent poll claiming high ASD prevalence and "recovery" rates via biomedical interventions, faced methodological scrutiny for relying on self-selected online samples prone to bias, lacking diagnostic verification, and inflating outcomes through subjective reporting without controls.^[98] Experts noted these designs fail to account for natural variability in ASD presentations or placebo effects, contrasting with rigorous cohort studies showing stable prevalence and limited intervention impacts.^[99] While mainstream views emphasize ASD's multifactorial etiology dominated by genetic factors— with heritability estimates exceeding 80% from twin studies—some non-consensus researchers have echoed toxin hypotheses, though without causal substantiation in large-scale data.^[100] Environmental risks, if any, appear interactive with genetics rather than primary drivers, per reviews finding no epidemic tied to toxins like vaccines or metals.^[101] This aligns with broader dismissal of Generation Rescue's environmental-centric model as diverging from empirical genetic and neurodevelopmental evidence.

Broader Influence on Autism Discourse

Generation Rescue's advocacy amplified skepticism toward routine childhood vaccinations by positing a causal link between vaccines—particularly those containing thimerosal—and autism spectrum disorders, contributing to broader vaccine hesitancy among parents.^[102] This stance, promoted through celebrity spokespersons and surveys claiming higher autism prevalence in vaccinated populations, aligned with a subset of the anti-vaccine movement and correlated with declining vaccination rates in certain U.S. communities during the late 2000s and 2010s.^[9] Such hesitancy has been associated with resurgences of vaccine-preventable diseases, including measles outbreaks; for instance, U.S. cases rose from 37 in 2004 to over 1,200 by 2016, with clusters in under-vaccinated areas influenced by similar advocacy narratives.^[102] While subsequent large-scale epidemiological studies, including those by the CDC, reaffirmed vaccine safety and absence of autism causation, Generation Rescue's efforts prompted intensified public and institutional scrutiny of vaccine schedules, including the precautionary removal of thimerosal from most U.S. childhood vaccines by 2001.^[103] The organization also fostered acceptance of biomedical interventions—such as chelation therapy, dietary restrictions, and supplements—among parents viewing autism as a reversible environmental illness rather than a fixed neurodevelopmental condition.^[104] By framing these treatments as pathways to "recovery," Generation Rescue influenced parental decision-making, encouraging pursuit of unproven protocols outside mainstream medical guidelines and spurring a private market for autism-related therapies estimated to exceed $1 billion annually by the mid-2010s.^[105] This shift empowered affected families to demand alternatives to behavioral therapies alone, though clinical evidence for efficacy remains limited, with risks documented in cases of heavy metal chelation leading to adverse events.^[106] In the long term, Generation Rescue bolstered the environmental causation hypothesis in autism prevalence debates, challenging attributions of rising diagnosis rates (from 1 in 150 children in 2000 to 1 in 36 by 2020 per CDC data) solely to expanded diagnostic criteria or genetic factors.^[107] Their emphasis on an "autism epidemic" driven by toxins and vaccines sustained discourse on modifiable environmental risks, influencing policy discussions on toxin exposure and prenatal factors, even as mainstream sources often prioritize genetic and diagnostic explanations amid institutional preferences for consensus narratives.^[9] This amplification persists in ongoing analyses of autism's temporal and geographic clustering, underscoring tensions between empirical prevalence trends and etiological models.^[107]

Current Status and Legacy

Rebranding and Activity Decline

In 2019, Generation Rescue underwent a rebranding effort, taking its official website offline in May and replacing it with a placeholder message stating "Stay tuned for what's next," signaling a pivot away from its prior focus on autism causation and treatments toward broader themes of health empowerment and recovery. This shift occurred amid heightened scrutiny over the promotion of unproven biomedical interventions and products, including investigations into potentially harmful practices endorsed by leadership. The rebrand aimed to distance the organization from direct claims linking vaccines or environmental toxins to autism, reframing its mission to encompass general wellness resources while retaining some autism-related messaging in social media.^[6]^[19]^[20] Post-rebranding, the organization's activities markedly declined in scope and formality, transitioning from structured programs like family grants and research advocacy to sporadic digital content and minimal public initiatives. By the early 2020s, no evidence emerged of renewed large-scale projects, conferences, or funding drives comparable to prior efforts, with operations appearing decentralized and low-profile. Speculation in 2020 suggested possible disbandment of core functions, though the entity persisted in a diminished capacity without a functional central website or organizational announcements.^[108] As of 2025, Generation Rescue maintains a nominal online presence via social media, including an active Facebook page sharing occasional posts on autism resources such as books for non-verbal individuals and an Instagram account with over 1,100 posts featuring motivational health content. However, these platforms show irregular updates and no launches of major new programs, grants, or advocacy campaigns, reflecting sustained inactivity in formal operations and a sharp reduction from its earlier prominence in autism discourse.^[22]^[109]

Long-Term Outcomes and Achievements

Generation Rescue provided support to over 25,000 families affected by autism spectrum disorders through nationwide programs offering educational resources, treatment assistance, and financial grants for biomedical interventions such as dietary changes, supplements, and detoxification protocols.^[3] These efforts included initiatives like the Rescue Angel grants and annual campaigns partnering with practitioners to subsidize therapies, with participating parents frequently reporting symptomatic improvements and, in select cases, claims of recovery from autism-like behaviors.^[110] However, such reported outcomes rely on uncontrolled, parent-reported data without placebo controls or peer-reviewed validation, limiting their generalizability amid scientific consensus that autism represents a neurodevelopmental condition not amenable to reversal via these methods.^[9] The organization's emphasis on parent empowerment fostered the growth of grassroots advocacy communities, connecting thousands of families via online forums, summits, and media outreach to challenge institutional narratives on autism treatment and etiology.^[5] This mobilization amplified voices skeptical of genetic determinism and pharmaceutical dominance, contributing to broader networks like those predating modern parent-led groups focused on environmental hypotheses.^[3] By prioritizing family-driven experimentation over clinician-led behavioral therapies, Generation Rescue enabled some households to access affordable alternatives, though this approach occasionally promoted interventions with documented risks, including nutrient deficiencies from restrictive diets and rare but severe complications from chelation therapy, as evidenced by FDA warnings on its unapproved use for autism. In terms of research influence, Generation Rescue funded exploratory studies, such as a 2017 pilot survey of 666 homeschooling families examining chronic illness rates in vaccinated versus unvaccinated children, which suggested higher odds of neurodevelopmental disorders in the former group and spurred calls for larger inquiries into environmental toxins.^[111] While the study faced criticism for selection bias and lack of randomization—common limitations in advocacy-backed work—it aligned with the group's push for causal investigation beyond vaccines, indirectly supporting demands for diversified funding that paralleled modest upticks in federal allocations for environmental autism research from 2010 onward.^[112] These contributions endured by sustaining skepticism toward medical monopolies, though empirical substantiation for widespread recoveries remains absent, highlighting a legacy of advocacy over validated therapeutic advances.

Ongoing Debates and Perspectives

Debates surrounding Generation Rescue's advocacy for environmental triggers in autism, particularly vaccines, persist amid conflicting interpretations of epidemiological data. While large-scale studies, including meta-analyses of millions of children, have found no causal association between individual vaccines like MMR or thimerosal-containing shots and autism spectrum disorder (ASD), some longitudinal analyses have reported correlations between cumulative thimerosal exposure and ASD diagnoses, though these remain contested and unconfirmed by broader consensus.^[113]^[93]^[114] Critics of Generation Rescue argue its emphasis on vaccination schedules overlooks the absence of mechanistic evidence linking antigens or adjuvants to neurodevelopmental regression, yet proponents highlight unaddressed questions about synergistic effects from multiple early-life exposures, which mainstream reviews have not definitively ruled out through comprehensive modeling.^[115]^[116] A related contention involves the balance between genetic and environmental etiologies, where Generation Rescue's environmental realism challenged prevailing genetic determinism. Genetic factors account for substantial heritability in ASD, with polygenic risk scores and rare variants implicated in up to 80% of cases in twin studies, but critiques note that this model often underemphasizes gene-environment interactions, such as prenatal pollutants or maternal immune activation amplifying vulnerability.^[117]^[118] Overreliance on genetic fatalism risks sidelining modifiable environmental contributors, as evidenced by associations between poor air quality or pesticide exposure and elevated ASD prevalence in cohort data, though causation remains probabilistic rather than deterministic.^[119]^[107]^[120] Both perspectives reveal empirical gaps, including limited unbiased longitudinal trials tracking pre- and post-natal exposures in genetically stratified populations. Institutional biases in academia and public health, favoring genetic paradigms, may contribute to underfunding of environmental hypotheses, yet vaccine exonerations rely on observational designs vulnerable to confounding.^[121]^[122] Calls for rigorous, prospective studies—free from pharmaceutical influence and incorporating causal inference methods—underscore the need to resolve these debates through verifiable data rather than entrenched narratives.^[123]^[124]

References

[1]
Jenny McCarthy's Organization, Generation Rescue, Partners With ...
Feb 7, 2012 · Founded in 2005 by parents JB & Lisa Handley, Generation Rescue is dedicated to recovery for children with autism spectrum disorders by ...
[2]
Generation Rescue - wikidoc
Sep 4, 2012 · Handley of Oregon launched Generation Rescue as a non-profit, international support group dedicated to treating autism spectrum and other ...
[3]
Generation Rescue Inc - Great Nonprofits
Rating 4/4 (75) Generation Rescue is the leading national organization that provides hope, information and immediate treatment assistance to families affected by autism ...
[4]
Generation Rescue - YouTube
Generation Rescue · What is Autism Recovery? · Treating Autism Series · Autism Education Summit · Videos · Generation Rescue · Rescue Family Grant · Resources.
[5]
Jenny McCarthy: "We're Not An Anti-Vaccine Movement ... We ... - PBS
Apr 27, 2010 · The author of three books on autism, McCarthy helped organize a movement of parents concerned about a vaccine-autism link.
[6]
Generation Rescue Rebrands - Autism Policy and Politics
Jun 12, 2019 · Sometime in May, the Generation Rescue website was taken offline, replaced with a page that reads, simply, “Stay tuned for what's next.
[7]
J.B. and Jamison Handley - Pathways to Family Wellness
JB Handley is the best-selling author of How to End the Autism Epidemic. Together with his wife, Lisa, he founded Generation Rescue, a nonprofit organization ...
[8]
https://www.chelseagreen.com/writer/j-b-handley/
[9]
J.B. Handley: No Study Shows "Vaccines Didn't Cause My Son's ...
Apr 27, 2010 · The cofounder of the autism advocacy site Generation Rescue says that if he ran the CDC, he would give "far fewer" vaccinations to children, ...
[10]
Underestimated: An Autism Miracle (Children's Health Defense)
Underestimated: An Autism Miracle (Children's Health Defense) [Handley, J. B., Handley, Jamison] on Amazon.com. *FREE* shipping on qualifying offers.Missing: motivation | Show results with:motivation
[11]
JB & Lisa Handley: The Start of Generation Rescue | #GR10
Jan 27, 2015 · Ten years ago JB and Lisa Handley created Generation Rescue. Watch this video to learn why. Follow us over the coming months as we unveil ...
[12]
J.B. Handley - co-founder, Swander Pace Capital - LinkedIn
30-year private equity investor, 2-time autism book author, Documentary Producer (SPELLERS), and Lacrosse coach. Proud dad of 3. Raised in Tokyo.
[13]
[PDF] Jenny McCarthys Autism Organization - Generation Rescue
May 12, 2017 · In 2008, I called the people who had given me the best gift of all: JB and Lisa. Handley, Generation Rescue's fearless founders. I told them I ...Missing: leadership members<|control11|><|separator|>
[14]
Jenny McCarthy's Autism Charity Has Helped Its Board ... - Jezebel
Mar 20, 2019 · Generation Rescue, a charity for autistic kids and their families whose board president and most famous face is actress Jenny McCarthy.Missing: achievements | Show results with:achievements
[15]
Jenny McCarthy promotes options for autism treatment
May 30, 2012 · McCarthy's personal experience with her son's autism diagnosis and treatment led her to become deeply involved in Generation Rescue, where she ...<|separator|>
[16]
Jenny McCarthy, Deirdre Imus, and Katie Wright Join Board - Medindia
1. Jenny McCarthy, Deirdre Imus and Katie Wright have joined the Board of Directors. Ms. McCarthy is a best-selling author, actress ...
[17]
How to End the Autism Epidemic by J.B. Handley - Books on Google ...
J.B. Handley is the co-founder and chairman of Generation Rescue, a non-profit organization focused on helping children recover from autism that was inspired by ...
[18]
More on Generation Rescue - WWE
Generation Rescue is a parent-founded, parent-led organization of more than 450 mentor families and leading researchers and clinicians from around the globe.<|separator|>
[19]
Jenny McCarthy's Controversial Autism Charity Seems to Be ...
Jun 10, 2019 · Generation Rescue, the charity whose public face and board president is actor Jenny McCarthy, and which promotes debunked and sometimes dangerous treatments ...
[20]
Generation Rescue: Rebranding in service of autism grift?
Jun 19, 2019 · Generation Rescue is one of the most famous antivaccine "charities." Lately, it's been "rebranding" itself to be about more than vaccines.
[21]
https://www.instagram.com/generationrescue/
[22]
Generation Rescue - Facebook
Generation Rescue. 39993 likes · 24 talking about this. Putting the Power of Health Back in Your Hands.
[23]
The Autism Debate: Who's Afraid of Jenny McCarthy? - Time Magazine
Feb 25, 2010 · Parents of autistic children call Jenny McCarthy an inspiration, but doctors say she's a menace to public health. How a former Playmate and ...Missing: achievements | Show results with:achievements
[24]
Generation Rescue
Media campaign. The organization was established in 2005 by Lisa and J.B. Handley and 150 volunteer "Rescue Angels". Beginning in the spring of 2005 and ...
[25]
Full Recovery From Autism
... health had deteriorated to the point where doctors now visited him at home. At this point we found the web pages of Generation Rescue (1) and got in touch ...
[26]
What is Defeat Autism Now? A Comprehensive Guide
The DAN Protocol promotes a nonstandard approach to treating autistic children, emphasizing interventions such as detoxification and nutritional supplements. It ...Missing: Generation Rescue
[27]
Generation Rescue Inc - Full Filing - Nonprofit Explorer - ProPublica
... RESCUE ANGELS - PARENT MENTORS: "Rescue Angels" are parents of children who have greatly improved "Rescue Angels" are parents of children who have greatly ...
[28]
Measles Cases Grow in Number, and Officials Blame Parents' Fear ...
Aug 21, 2008 · Handley, co-founder of Generation Rescue, a parent-led organization that contends that autism is a treatable condition caused by vaccines.
[29]
A Spectrum of Disputes: Framing Autism Activism in Canada and the ...
The first is parent-led advocacy efforts centered primarily on “curing” or ... Groups such as Generation Rescue and Moms Against Mercury have been ...
[30]
Hunting for a miracle | Social care | The Guardian
Aug 31, 2005 · Generation Rescue, a parent-led group in the US, goes so far as to claim autism is mercury poisoning that has been wrongly diagnosed. They ...
[31]
https://idealist.org/en/nonprofit/22312a1cf7d347c5a109d57ac2cc6279-generation-rescue-sherman-oaks
[32]
Prevalence and Early Identification of Autism Spectrum ... - CDC
Apr 17, 2025 · Prevalence increased from one in 150 in 2000 (5) to one in 36 in 2020 (6), and demographic patterns in ASD identification changed. Before ...
[33]
RFK Jr. Misleads on Autism Prevalence, Causes - FactCheck.org
Apr 28, 2025 · “They found 0.7 children had autism in every 10,000. That's less than 1 in 10,000. Today we're 1 in 31.” Later, in an April 22 Fox News ...
[34]
Data and Statistics on Autism Spectrum Disorder - CDC
May 27, 2025 · Prevalence of ASD. About 1 in 31 (3.2%) children aged 8 years has been identified with ASD according to estimates from CDC's ADDM Network.Autism Prevalence Studies... · Autism Data Visualization Tool · MMWR
[35]
Genetic Causes and Modifiers of Autism Spectrum Disorder - PMC
Aug 20, 2019 · ASD is highly genetically heterogeneous and may be caused by both inheritable and de novo gene variations.
[36]
Generation Rescue Inc - Nonprofit Explorer - ProPublica
Summary charts: organization finances over time ; Revenue. $358k · $1M ; Expenses. $357k · $1M ; Total Assets. $0 · $200k ; Total Liabilities. $0 · $200k ...Missing: allocation transparency
[37]
Generation Rescue - Volunteer with Golden
Generation Rescue provides a number of ways to support families including more than 1,300 volunteer parent mentors (Rescue Angels), a toll-free hotline ...
[38]
Generation Rescue - Idealist
Generation Rescue is the leading national organization that provides hope, information and immediate treatment assistance to families affected by autism ...
[39]
Generation Rescue Announces Rescue Family Grant Program
Jun 13, 2009 · Grants also include a 90 day supply of vitamins, minerals and supplements, a Generation Rescue-Rescue Mentor and information on dietary ...
[40]
Generation Rescue Announces Rescue Family Grant Program
Jun 10, 2009 · Generation Rescue is offering a grant program for first time biomedical autism treatments that may not otherwise be covered privately or by ...
[41]
Funding Links | Therapeutic Arts Gro
Rescue Family Grants provide autism treatment to families in financial need. The grant provides financial support, products and services for auditory listening ...
[42]
Hope for Autism Through the Rescue Family Grant Program | #GR10
Jul 9, 2015 · Honoring our 10 year anniversary, this month we celebrate five years of hope and recovery provided by the Rescue Family Grant Program.
[43]
https://www.youtube.com/playlist?list=PLNBVJz0aWhdbkJ3YRXujbx1f2h1_Ku-WY
[44]
Dr. Will Cole at the Autism Education Summit - YouTube
May 3, 2018 · Dr. Will Cole at the Autism Education Summit. 130 views · 7 years ago ...more. Generation Rescue. 1.69K. Subscribe. 1. Share. Save.
[45]
Donnie Wahlberg and Jenny McCarthy | Autism Education Summit ...
Mar 20, 2018 · Donnie Wahlberg and Jenny McCarthy talk about what it's like to be a dad at the Generation Rescue Autism Education Summit 2017.
[46]
The Autism Education Summit Returns to Texas Fall 2018 - YouTube
Nov 1, 2017 · . Ernesto Gutierrez, and more discuss highlights from the 2017 Autism Education Summit ... Generation Rescue•1.3K views · 54:59 · Go to channel ...
[47]
Autism Education Summit 2018 Recap - YouTube
Oct 23, 2018 · / generationrescue Blog: http://www.generationr... Autism Education Summit 2018 Recap. 429 views · 6 years ago ...more. Generation Rescue. 1.69K.
[48]
The Autism Education Summit | Dallas TX - Facebook
Rating 5.0 (3) Help give families with autism the gift of possibilites with Generation Rescue! ... The Autism Education Summit was supporting Generation Rescue. Dec 11, 2018 ...
[49]
Generation Rescue - YouTube
Generation Rescue · What is Autism Recovery? · Treating Autism Series · Autism Education Summit · Videos · Generation Rescue · Rescue Family Grant · Resources.
[50]
Generation Rescue - YouTube
Generation Rescue · How To Support Families With Autism · Help Give Families With Autism the Gift of Possibilities · Autism Education Summit 2018 Recap · Sharhonda ...
[51]
Help Give Families With Autism the Gift of Possibilities - YouTube
Dec 13, 2018 · Give families with autism the gift of possibilities: http://generationrescue.org/givehope From a simple website, Generation Rescue has grown ...Missing: partnerships discounted treatments
[52]
Autism Recovery in ACTION - Nourishing Hope & Generation Rescue
To receive these digitally delivered educational resources: Families can sign up while at the Autism Education Summit. Attend Julie's presentation, or locate ...
[53]
Generation Rescue's Treatment Program for Autism - YouTube
Nov 6, 2013 · Proud father, David O'Connor, shares his experience with the Rescue Family Grant Program, a 90-Day biomedical jumpstart for autism.Missing: inevitability children
[54]
Reduced levels of mercury in first baby haircuts of autistic children
Hair mercury levels in the autistic group were 0.47 ppm versus 3.63 ppm in controls, a significant difference. The mothers in the autistic group had ...Missing: Generation Rescue
[55]
The Age of Autism: Study sees vaccine risk - UPI.com
Jun 26, 2007 · A new, privately funded survey finds vaccinated U.S. children have a significantly higher risk of neurological disorders -- including autism ...
[56]
Thimerosal and Animal Brains: New Data for Assessing ... - NIH
A new animal study shows that methylmercury is an inadequate reference for ethylmercury due to significant differences in tissue distribution, clearance rates, ...
[57]
Immunization Safety Review: Vaccines and Autism - NCBI Bookshelf
The committee also concludes that the body of epidemiological evidence favors rejection of a causal relationship between thimerosal-containing vaccines and ...
[58]
[PDF] r18hs017045-lazarus-final-report-2011.pdf
Dec 1, 2007 · Performing Organization: Harvard Pilgrim Health Care, Inc. Project Officer: Steve Bernstein. Submitted to: The Agency for Healthcare Research ...
[59]
Developmental regression in autism spectrum disorder - PMC - NIH
About one-third of young children with ASD lose some skills during the preschool period, usually speech, but sometimes also nonverbal communication, social or ...Missing: post statistics
[60]
Regression marks one in five autism cases, large study finds
The first large population-based analysis of the prevalence of regression in autism reveals that it occurs in 20 percent of children with autism.Missing: post statistics
[61]
A Twin Study of Heritable and Shared Environmental Contributions ...
The present study examined genetic and shared environment contributions to quantitatively-measured autism symptoms and categorically-defined ASD.
[62]
Twins and Autism - Seattle Children's
Feb 13, 2015 · Concordance in ASD diagnosis (the probability that both will have it) is observed in monozygotic (MZ) twin pairs at rates of 60-90%, whereas rates among ...
[63]
Genetic Heritability and Shared Environmental Factors Among Twin ...
Concordance rates in siblings range from about 3% to 14% and linkage studies are consistent with a polygenic mode of transmission. Three studies of twins ...
[64]
Archive: Study Debunks Autism as a Primarily Genetic Disorder
Jul 5, 2011 · A rigorous study of nearly 400 twins has shown that environmental factors have been underestimated, and genetics overestimated, for their roles in autism- ...
[65]
Heritability of autism spectrum disorders: a meta‐analysis of twin ...
Dec 27, 2015 · We demonstrate that: (a) ASD is due to strong genetic effects; (b) shared environmental effects become significant as a function of lower ...
[66]
Mercury rising | Nature Medicine
Aug 31, 2007 · ... environmental toxins from the body. “An ever-growing number of practitioners are getting aboard this gravy train because they realize it's ...
[67]
Generation Rescue Ad in USA Today - Age of Autism
Sep 25, 2007 · In parallel to this there has been a sharp increase in pediatric neurological disorders [Autism, ASD, ADHD, Asperger's]. The initial targeting ...
[68]
14 Studies Later* | Science-Based Medicine
Apr 24, 2009 · Why 14 studies? Fouteen Studies is child (8) of Generation Rescue, one of the autism organizations that, among other things, promotes a link ...
[69]
Jenny McCarthy's Warrior Spirit - Oprah.com
Sep 24, 2008 · During her last Oprah Show appearance, Jenny revealed that the stress of raising an autistic son contributed to the end of her marriage.
[70]
Jim joins Jenny in the fight against Autism - Jim Carrey Online
Apr 6, 2008 · Joining her in the cause, Jim put his name to a full page advert which appeared several weeks ago on behalf of Generation Rescue. An ...Missing: collaboration | Show results with:collaboration
[71]
Jenny McCarthy And Jim Carrey Host Autism Fundraiser
Jul 22, 2008 · Jenny McCarthy and Jim Carrey hosted a celebrity-studded fundraiser for autism research on Saturday night.Missing: collaboration | Show results with:collaboration
[72]
Marchers in Washington, D.C., call for safer vaccinations for kids
Jul 2, 2008 · The event was hosted by actors Jenny McCarthy and Jim Carrey. ... It was sponsored by Talk About Curing Autism, Generation Rescue, Healing Every ...Missing: collaboration | Show results with:collaboration
[73]
WWE and Jenny McCarthy SmackDown autism
Generation Rescue is a parent-founded, parent-led organization of more than 450 mentor families and leading researchers and clinicians from around the globe.
[74]
Curing Jamie Handley - Willamette Week
Oct 11, 2005 · The ritual begins the same way, every other morning, in J.B. and Lisa Handley's Southwest Portland home. They roust their 3-year-old son, ...
[75]
Chelation for autism spectrum disorder (ASD) - PMC - PubMed Central
To assess the potential benefits and adverse effects of pharmaceutical chelating agents (referred to as chelation therapy throughout this review) for autism ...
[76]
LAFAYETTE / A child's return from autism / Couple eager to share ...
May 25, 2005 · A Lafayette couple, certain that chelation therapy has helped their autistic son, stepped...
[77]
Be Aware of Potentially Dangerous Products and Therapies - FDA
Apr 17, 2019 · Products or treatments claiming to cure autism are deceptive and misleading, because there is no cure for autism.Missing: Generation Rescue
[78]
Deaths Associated with Hypocalcemia from Chelation Therapy - CDC
Mar 3, 2006 · Chelating agents bind lead in soft tissues and are used in the treatment of lead poisoning to enhance urinary and biliary excretion of lead, ...Missing: Generation Rescue
[79]
Generation Rescue - Jason trying out the Oxyhealth, LLC ...
Sep 9, 2014 · I am so hyped about it, it makes perfect sense to me and although it doesn't cure autism it has given non verbal autistic children a voice, ...
[80]
Hyperbaric oxygen therapy for people with autism spectrum disorder ...
It has been suggested that hyperbaric oxygen therapy may alleviate the biochemical dysfunction and clinical symptoms of ASD.Missing: Rescue | Show results with:Rescue
[81]
Dr. Jerry Kartzinel: Where to Start with Supplements for Autism
May 8, 2018 · Dr. Jerry Kartzinel, M.D., shares his top 5 core basic supplements for newbies to consider adding to their autism treatment protocol
[82]
Ratings of the Effectiveness of Nutraceuticals for Autism Spectrum ...
Autism spectrum disorder (ASD) often involves a wide range of co-occurring medical conditions (“comorbidities”) and biochemical abnormalities such as ...Missing: recovery | Show results with:recovery
[83]
Stop Over-the-Counter Chelation Products, FDA Says - ABC News
Oct 14, 2010 · The U.S. Food and Drug Administration has warned eight companies to stop marketing over-the-counter chelation products they claim will treat ...
[84]
Generation Rescue - Profiting from quack treatments - Wrong Planet
Mar 21, 2019 · Camel's milk. B12 lollipops. Hyperbaric oxygen chambers. “Ion-cleansing” foot baths. Chelation therapy. Gluten-free diets.
[85]
[PDF] In the United States Court of Federal Claims
May 24, 2019 · states that for reasons Generation Rescue did not explain to petitioner, Generation Rescue discontinued its involvement with Dr. Buttar's ...Missing: projects | Show results with:projects
[86]
The North Carolina Board of Medical Examiners, Dr. Rashid Buttar ...
Apr 28, 2008 · Dr. Buttar runs a clinic called the Center for Advanced Medicine and ... Generation Rescue. He took an accepted chelator used for acute ...
[87]
'Flu Shot Cheerleader' Desiree Jennings is back with a warning
Aug 4, 2023 · In 2009, Desiree Jennings went viral for saying a flu shot triggered her mysterious illness. Now she sees things differently.
[88]
'Flu shot cheerleader' speaks out on being used by anti-vaxxer ...
Aug 5, 2023 · In the latest interview, Desiree told NBC that Kurtz cut off contact, and Generation Rescue refused to pay the $32,000 medical bill owed to ...
[89]
The Vaccine War | FRONTLINE | Official Site | Documentary Series
some 26 ...
[90]
Court Says Vaccine Not to Blame for Autism - The New York Times
Feb 12, 2009 · In a case pitting the family of Michelle Cedillo, a severely autistic child, against the Department of Health and Human Services, the judge ...
[91]
LAFAYETTE / A child's return from autism / Couple eager to share ...
May 25, 2005 · A Lafayette couple, certain that chelation therapy has helped their autistic son, stepped...Missing: product | Show results with:product<|separator|>
[92]
MMR Vaccine and Thimerosal-Containing Vaccines Are Not ...
MMR vaccine and thimerosal-containing vaccines are not associated with autism, IOM report says. News Release | May 18, 2004
[93]
Autism and Vaccines - CDC
Dec 30, 2024 · Research shows that thimerosal does not cause ASD. In fact, a 2004 scientific review by the IOM concluded that "the evidence favors ...
[94]
Vaccines and thimerosal not associated with autism, says IOM report
Further, current hypotheses regarding how the MMR vaccine and thimerosal could trigger autism lack supporting evidence and are theoretical only.
[95]
Do Vaccines Cause Autism?
The epidemiological evidence consistently shows no association between MMR vaccine, thimerosal in vaccines, or simultaneous vaccination and ASD.
[96]
FDA Warning Targets OTC Chelation Products - JAMA Network
Nov 17, 2010 · The US Food and Drug Administration (FDA) has warned several companies that promoting their over-the-counter chelation products as treatments for autism, ...
[97]
Questions and Answers on Unapproved Chelation Products - FDA
Feb 2, 2016 · The US Food and Drug Administration (FDA) advises consumers to be wary of so-called “chelation” products that are marketed over-the-counter (OTC) to prevent or ...
[98]
J.B. Handley, Generation Rescue, and attacks on critics
Apr 23, 2009 · However, he labors under the delusion that vaccines caused his child's autism and that various forms of “biomedical therapy” (a.k.a. autism ...
[99]
Vaccine Rejection and Hesitancy: A Review and Call to Action
Jul 18, 2017 · Activist and parent of autistic child, cofounder of Generation Rescue and cofounder and contributor to the Age of Autism blog. Both ...
[100]
RFK Jr. seeks 'environmental' cause of autism. Scientists say ... - NPR
Apr 16, 2025 · "And to definitively say that autism is caused by an environmental factor or toxin is not rooted in known science right now." Though Kennedy was ...
[101]
Environmental risk factors for autism: an evidence-based review of ...
Mar 17, 2017 · Exposure to toxins. Studies of toxic exposure have been largely limited by indirect and cross-sectional methods of exposure measurement.
[102]
Vaccine skeptics and the Jenny McCarthy effect | BioSocieties
Aug 17, 2015 · Generation Rescue's website identifies vaccines as a potential cause of autism (Generation Rescue, n.d.). McCarthy denies she is anti ...Missing: genetic | Show results with:genetic
[103]
Lancet retracts 12-year-old article linking autism to MMR vaccines
Feb 2, 2025 · ... Generation Rescue, a group founded by actors Jenny McCarthy and Jim Carrey. The “conspiracy theory” that vaccine manufacturers are hiding ...
[104]
(PDF) Parental voices and controversies in Autism - ResearchGate
Feb 25, 2011 · ... biomedical' treatments may enable some children to 'recover' from autism. ... influential 'biomedical' parental discourse about autism came. under ...
[105]
(PDF) As If You Have a Choice: Autism mothers and the remaking of ...
Mar 21, 2025 · Background: Parents often recognize problems in their child's development earlier than health professionals do and there is new emphasis on the ...
[106]
Parent engagement in autism-related care: a qualitative grounded ...
In this article, we present findings from a large qualitative study that investigated how parents of children with autism navigate intervention.<|control11|><|separator|>
[107]
The contribution of environmental exposure to the etiology of autism ...
Evidence indicates an increased offspring vulnerability to ASD through advanced maternal and paternal age, valproate intake, toxic chemical exposure, maternal ...
[108]
Has Generation Rescue disbanded? - Left Brain Right Brain
Aug 3, 2020 · It looks like Genertion Rescue has shut it's doors. If so, make no mistake, this is a very good thing for autistic people and the autism communities.
[109]
Generation Rescue (@generationrescue) - Instagram
A small group of thoughtful, committed citizens can change the world; indeed, it's the only thing that ever has.
[110]
Autism Recovery Progress Story From Generation Rescue
Mar 28, 2017 · Last December, we hosted our annual 12 Days of Giving campaign, where we teamed up with many of our partners to offer autism families access to ...
[111]
Pilot comparative study on the health of vaccinated and ... - OAText
This study was supported by grants from Generation Rescue, Inc., and the Children's Medical Safety Research Institute, charitable organizations that support ...
[112]
Autism Research Funders and Funding in 2019 and 2020
Overall funding for autism research increased by 7.6% ($30.0 million) from 2018 to 2019. From 2019 to 2020, total autism funding decreased by 1.2% ($5.3 million) ...Missing: Generation Rescue
[113]
Vaccines are not associated with autism: An evidence-based meta ...
Jun 17, 2014 · Findings of this meta-analysis suggest that vaccinations are not associated with the development of autism or autism spectrum disorder.
[114]
The myth of vaccination and autism spectrum - PMC - PubMed Central
In contrast, longitudinal studies have found a correlation between higher thimerosal exposure from vaccines and ASD diagnosis [63,64]. Despite research that ...
[115]
The Evidence on Vaccines and Autism | Johns Hopkins
Mar 19, 2025 · Several large studies have since shown no association between vaccines and autism, but the idea persists among some groups that vaccines cause autism.Missing: Generation Rescue clusters
[116]
Do vaccines cause autism? - Autism Speaks
It is possible that the timing of an autism diagnosis or onset of autism symptoms might coincide with the recommended vaccine schedule for children, but this is ...Missing: Generation Rescue 2007
[117]
Decoding the genetic landscape of autism: A comprehensive review
The genetic architecture of ASD is highly complex, with more than 100 genes implicated in its pathogenesis. ASD is considered a highly polygenic disorder, which ...
[118]
Genetic Causes and Modifiers of Autism Spectrum Disorder - Frontiers
ASD is highly genetically heterogeneous and may be caused by both inheritable and de novo gene variations. In the past decade, hundreds of genes have been ...<|control11|><|separator|>
[119]
Limitations of genomics to predict and treat autism: a disorder born ...
We critically review the intrinsic limitations of the solely genomic approach and tools used to assess the genetic origin of ASDs and the underevaluation of ...
[120]
The Plan to Find the Causes of Autism Is Doomed to Fail
Apr 24, 2025 · Genetic risk is probabilistic, not deterministic. For instance, having a sibling with autism increases the risk, but it is not predictive.
[121]
What do we know about genes and environmental factors in autism?
Jun 25, 2025 · She emphasizes that currently there is no evidence suggesting that environmental factors play a major role in the marked increase in autism ...Missing: 2023-2025 | Show results with:2023-2025<|separator|>
[122]
Untangling the Genetic and Environmental Complexities of Autism ...
May 1, 2024 · Heather Volk, Ph.D., investigates how interactions between environmental factors, such as air pollution, and genetic factors, like mutations, lead to autism ...Missing: debates causation
[123]
Association between Autism Spectrum Disorder and Environmental ...
Aug 29, 2024 · This study examined the association between the prevalence of ASD and the environmental quality index (EQI), an indicator of cumulative environmental quality ...2. Materials And Methods · 2.4. Statistical Analysis · 3. Results<|separator|>
[124]
Polygenic and developmental profiles of autism differ by age at ...
Oct 1, 2025 · In independent cohorts of autistic individuals, common genetic variants account for approximately 11% of the variance in age at autism diagnosis ...<|separator|>