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Hy

Hy may refer to: == Science and technology ==
  • [[Hy (programming language)]], a dialect of Lisp embedded in Python
  • H-Y antigen, a minor histocompatibility antigen
  • Hy's law, a guideline in drug-induced liver injury assessment
  • HY (satellites), a series of Chinese meteorological satellites
== Other uses ==
  • HY (band), a South Korean boy band
  • Hy (island), an island in the Philippines
  • Hy (name), a given name or surname
  • hy (company), a technology company (hypothetical or specific context)
== Linguistics and communications ==
  • Armenian language code (ISO 639-1: hy)
  • Texting slang for "hey" or similar abbreviations

Science and technology

Hy (programming language)

Hy is a dialect of the Lisp programming language designed for seamless interoperability with Python. It functions by translating Lisp s-expressions into Python's abstract syntax tree (AST), enabling Hy code to compile directly into Python bytecode and execute within the Python runtime. This approach allows developers to combine Lisp's homoiconic syntax—treating code as data—with Python's vast ecosystem of libraries, tools, and frameworks, without requiring bridges or wrappers. As part of the Lisp family, Hy emphasizes metaprogramming while inheriting Python's practicality for general-purpose programming. Hy was developed starting in 2013 by Paul Tagliamonte and the HyCore team, with its first release occurring in the same year during the Python Conference (PyCon). The language emerged from Tagliamonte's work on swarm behavior simulations, aiming to embed Lisp's expressive power into Python to facilitate advanced code generation and customization. Over the subsequent years, the project evolved through community contributions, focusing on robust integration and real-world applicability. Key features of Hy include its macro system, which supports compile-time code transformation for creating domain-specific languages or simplifying repetitive patterns, such as defining custom control structures like a do-while loop. It inherits 's dynamic typing, ensuring flexible variable handling and runtime evaluation, while allowing direct invocation of Python libraries in syntax—for instance, using s-expressions to call functions from packages like for numerical computations or CherryPy for web serving. This extends to mixing Hy and Python code in the same module, promoting gradual adoption in existing projects. Hy finds use cases in embedding Lisp-style paradigms within Python ecosystems, particularly for tasks requiring , such as generating optimized data processing pipelines in or building extensible web applications. Examples include scripting complex simulations with functional constructs or extending Python frameworks with macro-driven configurations. As of November 2025, Hy sustains an active community through GitHub contributions and discussions, with the current stable version 1.1.0 released on , 2025, following the milestone version 1.0 release in September 2024 that featured improved performance optimizations, API stabilizations, and enhanced compatibility with 3.x versions after nearly 12 years of development.

H-Y antigen

The H-Y antigen, also known as the Y antigen, is a set of minor histocompatibility antigens encoded by genes on the and expressed on the surface of cells in genetic males, leading to immune recognition by females as foreign. These antigens arise from Y-linked proteins such as SMCY and DBY, which have X-chromosome homologs but differ in key peptide sequences presented by ( and II molecules, eliciting T-cell and responses. Discovered in the 1950s through skin transplantation studies, the H-Y antigen was first identified when mice rejected grafts from syngeneic males, a phenomenon termed the "H-Y factor" by Eichwald and colleagues, with further confirmation in the 1970s via cytotoxic T-lymphocyte assays demonstrating its role in models. In humans, Goulmy et al. in 1977 described HLA-restricted cytotoxic responses to H-Y, establishing its relevance beyond . By the , molecular identification revealed multiple H-Y epitopes, including those derived from SMCY (e.g., an 11-residue presented by HLA-B7) and DBY (e.g., restricted by HLA-DQ5), which are recognized by + and + T cells, respectively. Initially proposed in the as the testis-determining factor due to its male-specific expression and association with gonadal development, the H-Y was later distinguished from the SRY , the true initiator of male sex determination on the Y chromosome's short arm. Current understanding positions H-Y as influencing post-SRY gonadal differentiation, potentially through ubiquitously expressed Y-linked proteins like UTY and SMCY that support and cellular functions, though its direct role in testis formation remains indirect and non-essential. In transplant , H-Y antigens drive male-specific rejection, with female-to-male transplants showing 1.5- to 4-fold higher chronic risk due to donor T-cell responses against recipient H-Y epitopes, while male-to-female transplants exhibit elevated acute rejection rates, often with H-Y development in over 50% of cases. Clinically, these antigens contribute to male-biased autoimmune conditions, such as secondary , where anti-H-Y antibodies are detected in 46% of affected women versus 19% of controls, suggesting a role in immune-mediated pregnancy loss. Specific epitopes like SMCY and DBY are immunodominant targets in these responses, informing strategies for sex-mismatched donor selection.

Hy's law

Hy's law is a clinical guideline named after hepatologist Hyman J. Zimmerman for predicting severe drug-induced (DILI), stating that hepatocellular injury accompanied by elevated serum (excluding cases due to biliary obstruction or ) signals a high risk of fatal outcome with mortality rates of 10% or higher. The rule applies specifically to idiosyncratic reactions where the liver damage impairs excretion, leading to as a marker of seriousness. The diagnostic thresholds for Hy's law require () levels greater than three times the upper limit of normal (ULN), total greater than two times the ULN, and at least 50% of the bilirubin elevation attributable to the drug rather than other causes. should remain below substantially elevated levels to confirm a hepatocellular pattern without significant . Developed in the based on case studies of idiosyncratic liver reactions, Hy's law formalized Zimmerman's seminal observation from his textbook on , where he noted the poor prognosis of jaundiced hepatocellular cases. The term was coined in the 1980s by FDA official Robert Temple to highlight its predictive value in drug safety assessments. In practice, Hy's law is employed by regulatory agencies such as the U.S. (FDA) and the (EMA) for monitoring liver safety in clinical trials and post-marketing surveillance. A single confirmed Hy's law case during development raises concerns, while two or more often prompts halting trials or market withdrawal, as exemplified by the 2000 FDA withdrawal of (Rezulin) after reports of fatal liver failures meeting these criteria. As of 2025, Hy's law criteria have been integrated into AI-based predictive models for screening in clinical trials, enhancing early detection through analyses of liver patterns and molecular data.

HY (satellites)

The HY series, standing for Haiyang () in , represents a family of marine satellites developed and operated by the , with the inaugural launch of HY-1A on May 15, 2002, marking China's first dedicated ocean color satellite. These satellites are managed by the National Satellite Ocean Application Service (NSOAS) under the (CNSA), focusing on monitoring ocean resources, environmental conditions, and dynamic processes to support and . By November 2025, the series includes over a operational and retired satellites across sub-series such as HY-1, HY-2, HY-3, and HY-4, with launches continuing to expand coverage. The primary capabilities of the HY satellites center on multispectral and microwave for parameters like , concentration, , and levels. For instance, the HY-1 series employs instruments such as the Chinese Ocean Color and Temperature Scanner (COCTS) and Coastal Zone Imager (CZI) to capture visible and imagery, enabling detection of algal blooms and coastal . Complementing this, the HY-2 series, starting with HY-2A in 2011, integrates altimeters, scatterometers, and microwave radiometers to measure sea surface height, wind fields, and wave heights, aiding in , , and marine safety. Later iterations like HY-3 and HY-4 incorporate (SAR) for all-weather imaging of and oil spills, enhancing year-round observation capabilities. Technically, most HY satellites operate in sun-synchronous low orbits at approximately 800 km altitude, providing revisit times of 1-3 days for global coverage. Optical sensors achieve resolutions up to 1 km, while instruments offer finer details for dynamic features like currents and swells. These specifications support applications in monitoring China's extensive coastal waters and contributing to international efforts, such as under the Decade of Ocean Science for (2021-2030). The series has enabled key achievements, including real-time alerts for marine disasters and integration into global oceanographic models, with data products distributed via NSOAS platforms to over 100 countries.

Other uses

HY (band)

HY is a Japanese rock band formed in 2000 by five high school friends in . The group blends elements of rock, , pop, rap, and traditional , often incorporating the sanshin instrument and drawing inspiration from the island's natural environment and culture. Their name derives from the initials of their hometown, Higashi Yakena in City. The band gained prominence in the indie scene through energetic street performances in , before achieving national success. The band's debut album, Departure (2001), achieved local popularity, but their breakthrough came with Street Story (2003), which topped the charts for four weeks—a record for an artist at the time. Their follow-up, (2004), also debuted at number one and featured the hit single "Song for…," which resonated with themes of and personal struggle. Subsequent releases like (2006) and major-label debut HeartY (2008) continued this chart dominance, marking HY as one of Japan's most successful acts of the . The current lineup includes Hideyuki Shinzato (vocals, guitar, leader), Shun Naka (drums, rap, chorus), Shinsuke Kyoda (bass), Izumi Nakasone (keyboards, vocals), and Yuhei Miyazato (guitar, vocals). HY has released over ten studio and compilation albums by 2025, including Whistle (2010), Glocal (2012), HANAEMI (2021), HONEY meets ISLAND CAFE presents HY Ocean Blue Sound ‐The Surf Remixes‐ (2021), Kafuu (2022), LOVE STORY HY BEST (2024), and TIME (2025), alongside best-of collections like HY SUPER BEST (2014). Their lyrics often explore themes of , , personal growth, and Okinawan identity, reflecting the members' roots and evolving softer melodic style with reduced emphasis on . Renowned for high-energy live performances, has built a dedicated fanbase through sold-out tours in . HY's cultural impact extends beyond Japan, popularizing Okinawan-influenced sounds globally through international tours, including the Japan Nite US Tour in 2007 (seven dates across the and ) and performances in , such as in 2024. As enduring pioneers, they have influenced the fusion of regional traditions with , maintaining relevance with prolific output and themes tied to environmental and youthful vitality.

Hy (island)

Hy, also spelled Í or I in Old Irish, signifies "island" and served as an early designation for Iona, a small island in the Inner Hebrides off the western coast of Scotland. This nomenclature reflects the linguistic conventions of the Gaelic-speaking peoples who inhabited the region, with the term appearing in early records predating widespread Christian influence. The island's strategic location in the Atlantic made it a focal point for maritime and cultural exchanges long before the arrival of Christianity. In 563 AD, the St. Columba (Colum Cille) arrived on with twelve companions and established a monastic community, transforming the island into a pivotal center of . The monastery, constructed from local materials, became a hub for learning, manuscript production, and missionary activity, embodying the distinctive Celtic monastic tradition that emphasized asceticism, scholarship, and evangelization. Under Columba's leadership until his death in 597 AD, Iona's community preserved Irish Christian practices while adapting to the Scottish and Pictish contexts. The name evolved over time, with Latin forms like Ioua appearing in seventh-century texts by Adamnán, the ninth abbot of , in his Vita Columbae, where the island is referred to as the "Iouan island (Hy)." By the eighth century, the form "Iona" emerged, possibly from a scribal error in interpreting Ioua, and it gradually supplanted earlier variants like Hy in common usage; traditional accounts also associate the island with the phrase Innis nan Druineach, interpreted as "island of the Druids," suggesting a pre-Christian sacred significance tied to Druidic practices. This linguistic persistence underscores Iona's enduring role in lore. Adamnán's work, completed around 697 AD, not only documented Columba's miracles and teachings but also cemented Hy's place in hagiographic . Iona's monastery played a crucial role in the Christianization of Scotland and the Pictish kingdoms, dispatching missionaries who converted King Óengus of the Picts in 565 AD and influenced royal courts across northern . The community's produced illuminated manuscripts, such as precursors to the , and its abbots held authority over daughter houses in Ireland and until the ninth century. As a of amid Viking raids that devastated the site in 795 AD and later, Iona symbolized resilience in the face of pagan incursions. Today, the abbey ruins are managed as a scheduled by , preserving its legacy as 's "cradle of Christianity." Archaeological investigations have uncovered layers of pre-Christian occupation beneath the monastic structures, including tools dating back over 8,000 years and a midden from around 1000 BC, indicating Iona's use as a or site in pagan times. Ongoing excavations by groups like the Iona Research Group continue to reveal these foundational pagan elements, providing context for the Christian overlay established by . These findings highlight the island's multifaceted history, blending prehistoric with early medieval faith.

Hy (name)

Hy is primarily used as a masculine or in English-speaking contexts, often serving as a for longer names such as Hyman, a Jewish Anglicization of the Hebrew Chaim meaning "life." It has also been recorded as a short form of Hiram, derived from the Hebrew for "exalted brother," particularly in 20th-century American usage among Jewish and Anglo communities. The name gained modest popularity in the United States during the early to mid-20th century, reflecting broader trends in abbreviated personal names, though it has since become rare. As a nickname, Hy frequently shortens names beginning with "Hy-" or similar sounds, including the given name Hyun (meaning "virtuous" or "clever") and compound names like Hyun-woo, as well as Western names such as . In Korean-American or multicultural settings, it appears as an informal variant of Hyun, aligning with practices for East Asian names. A prominent example is Hy Gardner (1908–1989), an American entertainment reporter and syndicated columnist for the , known for his celebrity interviews and coverage. Less commonly, Hy functions as a surname with diverse origins, including an English variant of High (from hēah, meaning "tall" or "noble") and a of the Korean surname Hyun, which ranks among common East Asian family names. It is also documented in Vietnamese contexts, where it is borne by over 3,500 individuals, often linked to regional phonetic adaptations. U.S. censuses from the 19th and 20th centuries record Hy sporadically as a surname among immigrant populations, though it remains uncommon overall. Notable bearers of the name include (1920–1997), an American director and producer recognized for episodes of and , and Hy Eisman (1927–2025), a comic artist who illustrated strips like and for nearly three decades. These figures highlight Hy's association with mid-20th-century American media and entertainment professions. In , the name exemplifies how short forms evolve across cultural boundaries. In contemporary trends as of 2025, Hy has seen niche resurgence as a prefix influenced by , where artists like those in groups such as incorporate "Hy-" elements (e.g., ), contributing to global naming inspirations among fans.

hy (company)

hy Co., Ltd. (Korean: 주식회사 에치와이) is a major South Korean food and beverage manufacturer headquartered in . Established in 1969 as through a with Japan's , the company initially focused on introducing fermented products to the Korean market, pioneering the use of in the country. It rebranded to hy in March 2021 to broaden its portfolio beyond into a wider range of health-oriented foods and beverages, aiming for global expansion as a comprehensive health food provider. As one of South Korea's leading food companies, hy maintains a strong domestic presence while increasingly targeting international markets. The company's core products include fermented milk drinks like its flagship Yakult probiotic beverage, as well as traditional Korean drinks such as (sweet rice punch) and (persimmon punch), alongside dairy items and health supplements. hy has diversified into functional foods, leveraging its extensive library of over 5,000 probiotic strains, many of which are proprietary and certified by bodies like the FDA and KFDA. By 2025, hy exports its products to over 20 countries, with a focus on and , driven by demand for K-probiotics and health beverages. Key milestones include serving as the official probiotic supplier for the and 1988 Seoul Olympics, and establishing Korea's first corporate in 1976 dedicated to and probiotics. In 2021, hy launched its B2B division hyLabs to supply probiotic ingredients globally. Financially, hy reported annual revenue of 1.68 KRW (approximately $1.2 billion USD) in 2024, marking a 10.8% increase from the prior year and underscoring its position among South Korea's top firms despite operating losses amid and portfolio shifts. The company employs over 1,000 people and operates multiple production facilities, including its central research center focused on natural ingredients and sustainable innovations. In response to global trends toward sustainable and alternative nutrition, hy has expanded into plant-based offerings since 2020, including the 2021 launch of its Protein Code brand featuring vegan protein drinks made from soy and . This initiative aligns with broader efforts to incorporate and vegan options, supporting environmental goals while addressing consumer demand for gut-healthy, non-dairy alternatives.

Linguistics and communications

Armenian language code

"hy" is the ISO 639-1 alpha-2 code assigned to the in the 2002 edition of the standard. The code derives from "Hayeren," the native endonym for the . (hy) belongs to the Indo-European language family and is spoken by approximately 6 million people worldwide, including both native and second-language speakers. It employs a unique alphabet, known as the Mesropian script, invented by the scholar in 405 AD to facilitate the translation of religious texts and promote literacy. The language features two principal modern dialects: , which was standardized during the Soviet era and bears influences from vocabulary and orthographic reforms, and , which is predominantly used by diaspora communities in countries such as , , and the . serves as the of , as enshrined in Article 20 of the country's constitution. It was also the of the (Nagorno-Karabakh) until its dissolution on January 1, 2024. In the digital realm, has benefited from support since version 3.0, released in September 1999, which introduced the Armenian (U+0530–U+058F) to enable consistent encoding across systems. As of 2025, advancements in AI-driven translation tools, including those from and , have significantly enhanced the language's global accessibility by providing real-time translation and capabilities for both Eastern and variants. Culturally, has been a vital medium for literary expression since , serving as the language of seminal works such as the by Movses Khorenatsi, a 5th-century often regarded as the father of for his comprehensive chronicle of the nation's origins and early rulers.

Texting slang

In digital communication, particularly within and platforms, "HY" serves as an primarily meaning "Hell Yeah" or the milder "Heck Yeah," used to convey enthusiastic , excitement, or . This expression emerged as part of the broader trend of abbreviated in informal texting, allowing users to quickly signal strong positive responses without full phrases. For instance, in a about plans, a reply like "Want to grab ? HY!" indicates eager consent. According to a linguistic of texting habits, "HY" for "Hell yeah" ranks among the most searched acronyms, with approximately 15,000 queries reflecting its widespread adoption in casual online interactions. An alternative interpretation of "HY" is a casual greeting, such as " you" or " ," functioning to initiate or maintain informal . This usage gained traction in the amid urban influences, particularly in quick messaging exchanges where brevity is prioritized. Examples include starting a text with "HY, what's up?" to prompt a response from a friend. It appears frequently in youth-oriented digital spaces, blending into everyday vernacular for friendly outreach. The evolution of "HY" traces back to the simplification of in early texting, with its enthusiastic affirmation sense documented in online slang resources by the late and proliferating through in the . By the mid-2020s, it had become embedded in Gen Z and Gen Alpha communities, often paired with emojis for emphasis, such as "HY 🔥" to amplify excitement in posts or comments. Regional nuances persist, with the "Hell Yeah" variant more prevalent in U.S.-based texting for its bold tone, while the greeting form sees broader use in informal chats. Despite its popularity in online and mobile contexts, "HY" remains unsuitable for formal writing due to its colloquial and potentially vulgar connotations in the primary sense.

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