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Alkanet

Alkanet, scientifically known as Alkanna tinctoria, is a perennial herbaceous plant in the Boraginaceae family, native to the Mediterranean region including southern Europe, North Africa, and parts of the Middle East.^[1] Growing to a height of about 0.2 meters with a spread of 0.3 meters, it features a weak, hairy stem, alternate oblong leaves, and small blue flowers that bloom in June, thriving in well-drained, calcareous soils under full sun or semi-shade.^[1] The plant is hermaphroditic and hardy to -10°C, often found in maritime sands, uncultivated ground, and pine forests across countries such as Spain, Italy, Greece, Turkey, and Algeria.^[1] Historically, alkanet has been valued for its roots, which contain naphthoquinone pigments that produce a water-insoluble red, violet, or crimson dye when extracted.^[2] This dye has been used since ancient times for coloring fabrics, cosmetics, oils, wines, and wood, with evidence of its application in traditional dyeing practices in regions like Italy and Sardinia, where roots were boiled to achieve brighter reds on wool and other materials.^[3] In addition to textile uses, the dye serves as a natural colorant in pharmaceuticals, perfumes, and even histological stains, and it has been employed as a food coloring agent, though modern regulations limit such applications due to potential toxicity concerns.^[2]^[1] Medicinally, alkanet root exhibits antibacterial, astringent, and vulnerary properties, traditionally applied externally to treat skin conditions such as ulcers, wounds, bruises, and varicose veins.^[1] Internal uses in systems like Ayurveda include remedies for digestive disorders, urinary calculi, jaundice, diarrhea, and inflammation, supported by studies showing antioxidant activity in root extracts and antibacterial effects from leaf extracts against multidrug-resistant bacteria like Staphylococcus aureus.^[4]^[5] However, caution is advised due to the presence of hepatotoxic pyrrolizidine alkaloids, which may pose risks of liver damage and carcinogenicity with prolonged use.^[1] Cultivation of alkanet is straightforward in dry, alkaline environments, with propagation via seeds or root cuttings, and it demonstrates drought tolerance once established.^[1] While the leaves are occasionally used as a vegetable, the plant's primary economic and cultural significance lies in its dyeing capabilities, distinguishing it from related species like green alkanet (Pentaglottis sempervirens), which lacks the characteristic red pigment.^[1]

Overview

Definition and Common Names

Alkanet is a common name for several plants in the Boraginaceae family, with the primary reference being Alkanna tinctoria, a herbaceous species valued for the red dye extracted from its roots.^[6] This plant, also known as dyer's alkanet, has been historically significant in dyeing applications due to the pigment in its root tissues.^[7] Botanically, Alkanna tinctoria is classified as a perennial herbaceous plant within the genus Alkanna, subfamily Boraginoideae, order Boraginales.^[8] The genus Alkanna comprises around 50–60 species, mostly distributed in the Mediterranean region and adjacent areas.^[9] Common names for Alkanna tinctoria vary by region and include alkanet, dyer's alkanet, dyer's bugloss, orchanet, Spanish bugloss, and Languedoc bugloss; in India, it is known as Ratanjot.^[7] The term "alkanet" may also refer to related Boraginaceae species, such as green alkanet (Pentaglottis sempervirens), though these are distinct in their uses and characteristics.^[6] Alkanet, specifically Alkanna tinctoria, is often confused with green alkanet (Pentaglottis sempervirens), a distinct species in the same Boraginaceae family that shares the common name but lacks the characteristic red dye in its roots. Green alkanet is an invasive perennial native to southwestern Europe, featuring bright blue, star-shaped flowers and evergreen leaves, primarily valued as an ornamental plant in gardens rather than for any dyeing applications.^[10]^[11] In contrast, European alkanet (Anchusa officinalis), another Boraginaceae member sometimes referred to as common or false alkanet, is a tall perennial with deep blue to purple flowers and hairy stems, historically employed for its medicinal roots to treat ailments like coughs and wounds, but it does not yield a viable red dye suitable for textiles or cosmetics.^[12]^[11] Among other Alkanna species, A. orientalis represents a relative with yellow flowers and roots containing alkannin derivatives, suitable for dye production, alongside its ornamental appeal and antibacterial properties in seeds.^[13]^[14] The primary identifier distinguishing Alkanna tinctoria from these relatives is its thick, purple roots rich in alkannin, which produce a oil-soluble red dye absent in green alkanet, Anchusa officinalis, or A. orientalis.^[11]^[13]^[12]

Botany

Physical Description

Alkanna tinctoria is an herbaceous perennial or short-lived perennial in the Boraginaceae family, typically behaving as a hemicryptophyte that forms a basal rosette of leaves during its first year of growth, from which flowering stems arise in subsequent seasons.^[15]^[16] The plant produces rough-hairy, setose-hispid stems that are procumbent or ascending, branched from the base, and reach heights of 10-30 cm, with simple or few-branched upper portions supporting the inflorescence.^[17] Leaves are alternate, linear-lanceolate to lanceolate, measuring 6-15 cm in length and 0.7-1.5 cm in width, acute at the apex, attenuate at the base, and covered in white setose hairs on both surfaces.^[17] The inflorescence consists of lax, few-flowered scorpioid cymes, 1-3 cm long and 1.5-3 cm wide, bearing tubular flowers with a cylindrical corolla tube 5-6 mm long, deep blue to purple lobes that are ovate, and a calyx of linear-lanceolate lobes 3-4 mm in length; blooming occurs from May to July depending on local conditions.^[17] The root system features a prominent taproot up to 20 cm long and 1-3 cm thick, dark red internally and the primary source of its characteristic dye, while the seeds develop as small, ovoid nutlets 2-2.5 mm long, dark brown, and tuberculate.^[16]^[17] Its overall hairy pubescence on stems and leaves represents an adaptation to the arid conditions of its native Mediterranean habitat, aiding in water retention.^[17]

Habitat and Distribution

Alkanna tinctoria, commonly known as alkanet, is native to the Mediterranean Basin, encompassing southern Europe from Spain and France eastward to Greece, Bulgaria, and Slovakia, as well as North Africa from Morocco to Egypt and parts of southwestern Asia including Anatolia (western Turkey), Israel, Jordan, Lebanon, and Syria.^[1] The plant thrives in rocky, calcareous soils that are well-drained and alkaline, often found in xeric grasslands, coastal habitats, maritime sands, uncultivated ground, and pine forests, where it demonstrates strong drought tolerance aided by its hairy leaves and stems.^[1]^[16] It prefers sunny slopes and can grow in nutritionally poor conditions, contributing to its prevalence in such arid, open environments.^[1] Beyond its native range, Alkanna tinctoria has become naturalized in parts of Asia, particularly the northern foothills of India, where it supports local dye production.^[16] Overall, its current global distribution reflects both natural spread and human-mediated dispersal for utilitarian purposes. Ecologically, Alkanna tinctoria functions as a pioneer species in disturbed soils, such as those in rocky outcrops and grasslands, helping to stabilize and initiate vegetation succession in dry, low-nutrient settings.^[16] Its blue to purple flowers, blooming in spring and summer, attract pollinators including bees, supporting local insect biodiversity in these Mediterranean ecosystems.^[1]

Chemical Composition

Key Compounds

The primary chemical constituents of Alkanna tinctoria roots responsible for its dyeing properties are the naphthoquinone pigments alkannin and shikonin, which occur as enantiomers along with various ester derivatives such as acetylalkannin, isovalerylalkannin, and β,β-dimethylacrylalkannin.^[18] These compounds can comprise up to 6% of the root dry weight, with reported maxima of 5.9% in certain Bulgarian populations analyzed via spectrophotometric methods on hexane extracts.^[19] Alkannin, the (S)-enantiomer, predominates in A. tinctoria roots at approximately 95% of the total alkannin/shikonin content, while shikonin, the (R)-enantiomer, constitutes the remaining ~5%, as determined by untargeted UHPLC-HRMS metabolomics across developmental stages.^[18] These lipophilic red pigments are soluble in non-polar solvents like oils and alcohols but exhibit low water solubility, enabling their use in lipid-based applications.^[20] They are also pH-sensitive, displaying a red hue in acidic conditions and shifting to blue in alkaline environments.^[21] Minor components in the roots include pyrrolizidine alkaloids such as triangularine, 7-angoylretronecine, and dihydroxytriangularine, which are present in trace amounts and known for potential hepatotoxicity due to their ability to form DNA-alkylating metabolites.^[22]^[23] The chemical structures of alkannin and shikonin were first elucidated in the 1930s, with alkannin isolated and characterized in 1936 by Brockmann and Schwenk from A. tinctoria roots.^[20] Contemporary identification and quantification rely on high-performance liquid chromatography (HPLC), including chiral variants to resolve enantiomeric ratios and derivatives with high precision.^[20]

Dye Extraction Process

The extraction of dye from alkanet roots (Alkanna tinctoria) traditionally relies on simple infusion methods to release the red pigments, primarily naphthoquinones like alkannin, into suitable solvents. For oil-based extraction, dried roots are ground into a powder or small pieces and soaked in a carrier oil, such as olive oil, at room temperature for 1-4 weeks, producing a deep red tincture used in cosmetics and wood finishing.^[24] Alcohol extraction follows a similar process: chopped or powdered roots are immersed in high-proof ethanol or spirits (e.g., vodka at 40-50% alcohol) in a sealed jar, steeped for 1-2 weeks with occasional shaking, yielding a potent red liquid due to the high solubility of the colorants in alcohol.^[25] In contrast, water-based soaking of the roots for several days or weeks extracts weaker purple tones, as the pigments exhibit limited aqueous solubility.^[26] Modern techniques employ solvent-based methods for higher purity and efficiency in isolating alkannin. Ethanol extraction involves homogenizing ground roots in a 60-95% ethanol solution at a solid-to-liquid ratio of 1:5 to 1:30, performed at room temperature for 3-6 minutes under high-speed agitation (2000-10,000 rpm), repeated 1-3 times, followed by filtration and concentration under vacuum at 50-60°C to obtain crude alkannin with yields of 2.5-3.2%.^[27] For purified extracts, supercritical CO2 extraction is used as a green alternative: roots are processed at pressures of 50-350 bar and temperatures of 30-80°C with a CO2 flow of 5-20 g/min, optimized at 175 bar and 80°C for maximum yield, followed by alkaline hydrolysis to release total alkannins at up to 1.47%, surpassing traditional solvent methods.^[28] Variants in preparation adapt the roots for specific uses, often starting with drying and grinding into powder for easier infusion. Powdered roots can be directly added to alcohol or oil for rapid extraction, reducing soaking time to days while maintaining color intensity. For dyeing applications, the tincture is combined with mordants like alum (potassium aluminum sulfate) to fix the color; fibers are pre-mordanted by simmering in a 15% alum solution (weight of fiber) for 1 hour, enhancing dye uptake and wash fastness without altering the extraction step itself.^[29]

Historical and Cultural Significance

Etymology and Naming

The term "alkanet" derives from the Arabic "al-ḥinnāʾ," referring to henna due to the similar reddish dye extracted from the plant's roots, entering European languages through Medieval Latin "alcanna" and Old Spanish "alcana" or its diminutive "alcaneta" by the mid-14th century.^[30] This nomenclature highlights the plant's primary value as a dye source, distinguishing it from true henna (Lawsonia inermis) while reflecting shared applications in coloring. The English "alkanet" first appeared in records around 1343, evolving from these Arabic and Iberian roots to denote the plant itself by the 1560s.^[31] In scientific nomenclature, the binomial Alkanna tinctoria was established by Ignaz Friedrich Tausch in 1824, building on Carl Linnaeus's earlier description as Anchusa tinctoria in the second edition of Species Plantarum (1762), with Linnaeus initially classifying it under Lithospermum tinctorium in 1753; the genus Alkanna directly echoes the Arabic origin, while "tinctoria" (Latin for "used in dyeing") underscores its utilitarian role.^[32] Variant names like "orchanet" emerged from Old French "orcanette," a diminutive further adapting the term in European herbal traditions by the 16th century.^[33] Across cultures, naming reflects the dye's vivid red hue, as seen in Indian traditions where "Ratanjot" denotes the root's coloring properties, used interchangeably for Alkanna tinctoria or related species in Ayurvedic and culinary contexts.^[34] Historical nomenclature often blurred distinctions, with 12th-century trade records in the Mediterranean confusing alkanet with true henna due to overlapping red dye uses in textiles and cosmetics, leading to interchangeable terms in early commerce.^[35]

Traditional Uses in Dyeing and Medicine

Alkanet root has been employed as a natural red dye since ancient times, particularly in textile coloring. In ancient Egypt, it was used to dye wool garments, with recipes preserved in the Leiden Papyrus (late 3rd–early 4th century CE) describing its combination with lime, vinegar, walnuts, and pomegranate bark to produce affordable purple shades as an alternative to expensive Tyrian purple from murex snails.^[36]^[37] This application extended to silk and wool fabrics, leveraging the root's alkannin pigment, which yields deep reds insoluble in water but extractable in oils and alcohols.^[38] In medieval Europe, alkanet continued as a key dyestuff for textiles, wood stains, and lake pigments in illuminated manuscripts, providing vibrant reds despite its limited lightfastness.^[38] It was also incorporated into cosmetics, such as lip colorants and ointments, with historical records indicating its role in fatty preparations for staining and preservation. The plant's trade along routes like the Silk Road facilitated its spread from the Mediterranean to broader Eurasian markets, where it colored fabrics, perfumes, and confections in Roman and Byzantine contexts.^[39] By the 19th century, however, the advent of synthetic dyes, notably alizarin synthesized in 1869–1870, caused a sharp decline in alkanet's commercial use due to the superior fastness and affordability of these alternatives.^[40] Medicinally, alkanet served as an astringent and antimicrobial agent in Greek and Islamic traditions, applied in wound dressings and salves to promote healing and prevent infection.^[41] Folk remedies across these cultures utilized root infusions for treating skin conditions like ulcers and burns, owing to its anti-inflammatory properties, and as a diuretic to alleviate urinary issues.^[41] These applications stemmed from the root's bioactive compounds, including alkannin, which exhibit cooling and styptic effects.^[42]

Cultivation and Production

Growing Conditions

Alkanna tinctoria thrives in well-drained, sandy or loamy soils with a neutral to alkaline pH, ideally ranging from 6.5 to 7.5, and shows a particular affinity for calcareous or limestone-based substrates that prevent waterlogging.^[43]^[44]^[45] These conditions mirror its native Mediterranean habitats, where the plant naturally establishes in rocky, low-fertility environments. The species prefers a Mediterranean climate characterized by hot, dry summers and mild, cool winters, with moderate rainfall typical of Mediterranean climates, concentrated in the cooler months to support growth without excess moisture.^[44]^[46] It is hardy in USDA zones 6 to 9, tolerating temperatures down to -10°C but requiring protection from prolonged frost in cooler regions.^[47]^[48] For successful cultivation, the plant can be propagated by sowing seeds in spring after the last frost, either directly in prepared beds or started indoors in warm conditions (around 20-25°C) for transplanting once seedlings develop two true leaves, or by dividing roots in autumn or spring.^[44]^[49]^[48] Plants are spaced approximately 30-50 cm apart to allow for their clumping growth habit and to ensure adequate air circulation, which aids in preventing fungal issues. Full sun exposure is essential throughout the growing season, as it promotes robust root development and enhances the concentration of pigment compounds in the roots.^[47] Minimal fertilization is recommended, as the plant performs best in nutrient-poor soils that mimic its natural preferences. Key cultivation challenges include susceptibility to root rot in overly wet or poorly drained soils, which can be mitigated by ensuring proper drainage and allowing the soil to dry between waterings.^[47] Additionally, while generally resilient, Alkanna tinctoria may encounter pest issues such as aphids, which can be managed through organic methods like introducing beneficial insects or using insecticidal soaps to avoid chemical residues that might affect dye quality.^[50] In regions with high humidity or cool, damp conditions, establishment can be difficult, often resulting in poor germination or stunted growth.^[44]

Harvesting and Processing

Alkanet roots are typically harvested in the second or third year of plant growth, during autumn, when pigment concentration peaks to optimize dye quality.^[48] This developmental stage maximizes the accumulation of key metabolites in the roots. After digging, the roots undergo initial processing by washing to remove adhering soil and debris, followed by chopping into smaller segments for efficient drying. Drying occurs at approximately 40°C to safeguard the heat-sensitive pigments from degradation. Processed roots are then stored in cool, dark environments, retaining potency for up to two years. Sustainability practices in alkanet production include crop rotation every three years to avert soil nutrient exhaustion and maintain long-term productivity. Organic certification is prevalent in contemporary farming operations, aligning with demands for natural, eco-conscious dye sources.

Modern Applications

Industrial and Artistic Uses

Alkanet, derived from the roots of Alkanna tinctoria, serves as a natural colorant in various industrial applications, particularly in cosmetics where it imparts reddish-purple hues to products like lipsticks and soaps due to its alkannin pigment.^[51] In the food industry, it has been used historically as a red-brown additive under the EU designation E103, though its approval has been withdrawn since 1976, limiting its current application to select regions like Australia.^[52] For textiles, alkanet provides eco-friendly purple shades on natural fibers such as silk and wool, with microwave-assisted extraction and bio-mordants enhancing color fastness while reducing environmental impact compared to synthetic dyes.^[53] In artistic contexts, alkanet is employed by dyers and craftspeople for hand-dyeing techniques, yielding subtle watercolor-like effects and lavender tones on fabrics when extracted in alcohol or water baths.^[25] It finds use in batik processes for creating layered purple and blue patterns on protein fibers, supporting creative experimentation in small-scale studios.^[54] Since the 2010s, there has been a revival of alkanet in sustainable fashion, driven by interest in non-toxic, plant-based alternatives amid growing demand for eco-conscious textiles.^[55] Global production of alkanet root powder is centered in India and Turkey, with the market valued at approximately USD 1.2 million in 2024 and projected to grow at a 9% CAGR through 2033.^[56] Pricing for the powder typically ranges from $30 to $65 per kg, reflecting its niche status in natural dye supply chains.^[57]

Safety and Regulatory Considerations

Alkanet (Alkanna tinctoria) root contains pyrrolizidine alkaloids (PAs), which are hepatotoxic compounds capable of causing liver damage, including veno-occlusive disease, when ingested in sufficient quantities.^[58] These alkaloids are metabolized in the liver to form reactive pyrrole metabolites that bind to cellular proteins and DNA, leading to toxicity; the World Health Organization's Joint FAO/WHO Expert Committee on Food Additives has highlighted their carcinogenic potential in animal models, primarily inducing liver hemangiosarcomas.^[59] While topical application is generally considered safe due to minimal systemic absorption, internal use is strongly discouraged to avoid risks of acute or chronic liver injury.^[60] In the United States, alkanet has been prohibited for use as a food coloring since its delisting by the Food and Drug Administration in 1964, following provisional approval with no demonstrated industry interest or safety data sufficient for permanent listing.^[61] Conversely, in the European Union, alkanet root extract is permitted in cosmetics under the Cosmetics Regulation (EC) No 1223/2009 and complies with REACH requirements for substance registration, provided it meets purity and safety standards.^[62] However, due to potential for contact dermatitis, manufacturers must include allergen warnings on products containing alkanet for individuals with sensitive skin or known allergies to Boraginaceae family plants.^[58] To mitigate risks, alkanet extracts should always be diluted in carrier oils or bases before topical use, and internal consumption avoided entirely.^[60] It is contraindicated during pregnancy and breastfeeding, as PAs may cross the placental barrier or enter breast milk, potentially causing fetal or infant liver toxicity.^[60] Recent research, including a 2023 study on alkannin—a key naphthoquinone derivative—demonstrates potential anti-inflammatory benefits at low doses by inhibiting NF-κB and MAPK pathways in lipopolysaccharide-induced models, suggesting therapeutic promise for external applications when risks are controlled.^[63]

Green Alkanet (Pentaglottis sempervirens)

Green alkanet (Pentaglottis sempervirens) is an evergreen perennial herbaceous plant in the Boraginaceae family, closely related to Alkanna tinctoria. It typically reaches heights of 60-90 cm, with erect stems covered in stiff hairs and a deep taproot system. The plant forms a basal rosette of large, rough, heart-shaped leaves up to 40 cm long, which are ovate and alternately arranged along the stems. From April to June, it produces clusters of bright blue flowers, each about 8-10 mm in diameter with a white center, followed by small black nutlet seeds. Native to the Iberian Peninsula in southwestern Europe, it was introduced to other regions as an ornamental plant over 300 years ago.^[64]^[65]^[66] This shade-tolerant species thrives in partial to full shade, preferring moist, well-drained soils in disturbed areas such as gardens, woodlands, hedgerows, roadsides, and forest edges. In the United Kingdom, it has naturalized widely, particularly in southern England, where it forms dense ground cover and spreads aggressively via seeds and root fragments, often outcompeting native vegetation in shady, damp habitats. Similarly, in the United States, it is established in lowland areas from British Columbia to California, including widespread presence in western Washington, where it invades gardens and woodlands. Classified as a Class C noxious weed in Washington State since 2022, it is prohibited from transport, sale, or distribution due to its weedy spread.^[64]^[66]^[67] Valued as an ornamental for its vivid blue blooms, green alkanet serves as an excellent bee plant, with nectar-rich flowers attracting pollinators like bees, hoverflies, and butterflies, while its foliage supports larvae of species such as the scarlet tiger moth. However, its roots produce a weaker red dye compared to Alkanna tinctoria and it poses significant management challenges; its deep, thick roots make eradication difficult, often requiring persistent manual digging to remove the entire taproot and monitoring for regrowth from fragments or seedlings. In invasive contexts, cutting back flowering stems before seed set is recommended to limit spread, though complete removal may necessitate repeated efforts over multiple seasons.^[65]^[64]^[66]

Other Alkanna Species

The genus Alkanna includes approximately 60 species of herbaceous perennials belonging to the Boraginaceae family, primarily distributed across southern Europe, western Asia, and North Africa. These species typically feature blue to violet flowers, hispid stems, and basal rosettes of leaves, with many inhabiting rocky or mountainous terrains. Unlike A. tinctoria, which is renowned for its high concentration of alkannin pigments in the roots, other Alkanna species generally exhibit lower levels of these naphthoquinones, resulting in reduced dyeing potential or alternative secondary metabolites.^[68] Alkanna orientalis, native to the southern and eastern Mediterranean regions extending to western and central Iran, thrives as a perennial in temperate, rocky habitats at elevations up to 2200 meters. While its roots yield a red pigment similar to that of A. tinctoria, the alkannin content is notably lower, producing a weaker dye suitable for limited traditional applications. This species is adapted to arid conditions, forming monotypic patches in desert-like areas.^[69]^[70]^[71] Alkanna strigosa, endemic to the eastern Mediterranean including western Syria, Lebanon, Israel, Jordan, and the Sinai Peninsula, is a chamaephytic perennial valued for its ornamental qualities due to its dark blue flowers blooming from February to May. It grows in subtropical, open scrublands and is distinguished by its bristly, hispid foliage and short pedicels bearing solitary flowers, making it suitable for horticultural use in dry, well-drained soils. Unlike A. tinctoria, its root pigments are minimal, limiting its role in dyeing.^[72]^[73]^[74] Alkanna sieberi is restricted to mountainous regions of Greece, where it occurs as a perennial in high-altitude, calcareous soils. The species shares the genus's typical blue inflorescences but is adapted to cooler, alpine-like environments.^[75] Conservation concerns affect several Alkanna species due to habitat loss from urbanization and overgrazing in their native ranges. For instance, A. cappadocica, endemic to inner Anatolia in Turkey, is classified as Rare under 1997 IUCN criteria and faces ongoing threats from habitat loss and overgrazing.^[76]^[77]

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By Any Other Name: Words for Henna Across the World
May 12, 2014 · ' Alkanet (Alkanna tinctoria), a Mediterranean plant whose roots produce a red dye, owes its name to the Arabic al-ḥinnā' but is unrelated to ...<|separator|>
[36]
Deep Purple: Dyeing Egyptian Textiles - Papyrus Stories
Jun 1, 2020 · The recipe makes use of the alkanet plant, whose dark red roots were used to create dye. Another procedure in the codex combines alkanet with ...
[37]
[PDF] alkanna tinctoria (l.) tausch as purple dye in the recipes of papyrus ...
Jan 17, 2013 · It could be proved that alkanet is suitable to achieve a broad spectrum of purple shades by various procedures. 1. Introduction. Both papyri ...Missing: scholarly | Show results with:scholarly<|separator|>
[38]
Alkanet - CAMEO
Oct 28, 2020 · The colorant has been used as a cosmetic, textile dye, wood stain, lake pigment, and for medicinal purposes. Synonyms and Related Terms. Anchusa ...
[39]
Dyer's Alkanet
In Europe and North America , Alkanna tinctoria is mainly used today as a pigment for food coloring and cosmetics.
[40]
A Brief History of Colour, the Environmental Impact of Synthetic Dyes ...
The use of ingredients distilled from coal tar enabled the development of new dyes, and by 1869 some natural dyes such as Alizarin was replaced by synthetic ...Missing: 1870s | Show results with:1870s
[41]
Avicenna's views on pest control and medicinal plants he prescribed ...
Feb 22, 2024 · Medicinal plants introduced as pesticides in Avicenna's Al-Qanun Fi Al-Tibb ; 13. Alkanet. Abukhalsā. Alkanna tinctoria (L.) Tausch.
[42]
Alkanna - Uses, Side Effects, and More - WebMD
Alkanna is a plant. The root and leaves are used to make medicine. People use alkanna for wound healing, burns, diarrhea, and stomach ulcers.
[43]
Alkanet - healing herbs - Herbs2000.com
Alkanet tea is used to soften and soothe irritated skin, it also finds use as a potent diuretic, as well as an astringent and a blood purifier.Missing: Avicenna Greek Islamic
[44]
How to identify Dyer's alkanet (Alkanna tinctoria) | PlantJoy
Alkanna tinctoria can be identified by its rough, hairy leaves and bright blue to purple flowers. The plant has a deep red root, which is a notable ...
[45]
Growing Alkanet, a Natural Purple Dye (Alkanna tinctoria)
Jan 5, 2024 · This plant looks similar to dyers alkanet and can even be used in dyeing, but it doesn't have alkanna tinctoria's deep purple color.Missing: botanical | Show results with:botanical
[46]
Alkanna tinctoria (Alkanet) - Practical Plants
May 4, 2013 · Prefers a well-drained sandy or loamy soil in sun or partial shade. Dislikes acid soils but thrives in alkaline soils. A very drought tolerant ...Missing: elevation | Show results with:elevation
[47]
Alkanna tinctoria: Ayurvedic Wiki Page by Ask Ayurveda
May 30, 2025 · Botanical Description and Taxonomy ; Kingdom: Plantae ; Order: Boraginales ; Family: Boraginaceae ; Genus: Alkanna ; Species: A. tinctoria.
[48]
How to Grow and Care for Dyer's alkanet - PictureThis
Attributes of Dyer's alkanet ; Plant Type. Herb ; Lifespan. Perennial ; Spread. 30 cm ; Flower Color. Purple. Blue ; Flower Size. 5 mm to 8 mm.Missing: height | Show results with:height<|control11|><|separator|>
[49]
Alkanna tinctoria Alkanet, Alkanna PFAF Plant Database
Alkanna tinctoria is a PERENNIAL growing to 0.2 m (0ft 8in) by 0.3 m (1ft). It is in flower in June. The species is hermaphrodite (has both male and female ...
[50]
How to Grow and Care for Alkanna - PictureThis
For seeds, sow in well-draining soil at a depth twice the seed's diameter and keep at 20-25°C with consistent moisture and indirect light. Root cuttings should ...
[51]
https://pdfs.semanticscholar.org/7b01/3a1dc4718625e83f9ba8d1b28438fb8375cf.pdf
[52]
ALKANET for your Natural Dyeing needs in the UK
In stockSow thinly – about 1/4 inch deep in drills and about 12 inches apart. They prefer poor soil so do not fertilize. Thin out superfluous seedlings so that the ...
[53]
https://doi.org/10.1016/j.indcrop.2022.115301
[54]
[PDF] Formulation and Evaluation of Herbal Lipstick Containing Alkanet ...
Herbal lipstick contains pigments, antioxidants, waxes, oils, fragrance and preservatives. Alkanet root is used as natural source of red pigment in cosmetics, ...Missing: soaps | Show results with:soaps
[55]
E103 – Alkanet - proE.info
This bright orange dye was banned by Directive 76/399/EEC of the European Council on April 6, 1976.Missing: restricted | Show results with:restricted
[56]
https://www.linkedin.com/pulse/alkanet-root-powder-market-key-insights-trends-a4vlc
[57]
Alkanet Root Dyeing | Textile Investigations - WordPress.com
Jul 16, 2016 · Alkanet dye is not particularly soluble in water, and for best results an alcohol extraction is required. I did this by filling a jar up with ...Missing: process traditional
[58]
A recent (2009–2021) perspective on sustainable color and textile ...
This review gives the present status of natural colorants, natural dyeing and color presentation, natural dyeing methods, technique, and performance<|separator|>
[59]
Alkanet Root Powder Market Growth Drivers and Key Trends
Aug 14, 2025 · Alkanet Root Powder Market size is estimated to be USD 1.2 Million in 2024 and is expected to reach USD 2.5 Million by 2033 at a CAGR of 9% from ...Missing: Turkey kg
[60]
Alkanet Root Natural Dye 5.07 Pound (2.3 Kilo/81.13oz) - Etsy
In stock Rating 4.6 (1,125) May include: A resealable plastic bag filled with dark reddish-brown Alkanet root powder. Price:$150.50.Missing: per kg
[61]
Alkanna Root Uses, Benefits & Dosage - Drugs.com
Like some other members of the Borage family, pyrrolizidine alkaloids have been found in Alkanna tinctoria, but levels have not been determined.Bisset 1994 ...
[62]
[PDF] Pyrrolizidine alkaloids - Inchem.org
Supplement 2: Pyrrolizidine alkaloids. Geneva: World Health. Organization and Food and Agriculture Organization of the United Nations; 2020 (WHO Food Additives ...
[63]
Alkanna: Health Benefits, Side Effects, Uses, Dose & Precautions
Liver disease: Alkanna contains chemicals called hepatotoxic pyrrolizidine alkaloids (PAs). These chemicals harm the liver, making existing liver disease worse.
[64]
Regulatory Status of Color Additives - cfsanappsexternal.fda.gov
CAS Reg No or other ID code: 977000-19-3. Color: Alkanet (Alkanna). Status: Delisted, formerly exempt from certification. Use: None, formerly Foods.Missing: EU E103 restricted
[65]
Ingredient: ALKANNA TINCTORIA ROOT EXTRACT
Alkanna Tinctoria Root Extract is an extract of the roots of the Dyer's Alkanet, Alkanna tinctoria L., Boraginaceae ... Cosmetics Regulation provisions. Functions.Missing: REACH | Show results with:REACH
[66]
Alkannin reverses lipopolysaccharides-induced inflammatory ...
Alkannin (ALK) reverses LPS-induced inflammation by suppressing NF-κB and MAPK signaling, reversing increased inflammatory markers.
[67]
Green Alkanet | RHS Advice
### Summary of Green Alkanet (Pentaglottis sempervirens)
[68]
Complete Guide to Green Alkanet | BBC Gardeners World Magazine
Mar 10, 2025 · Green alkanet (Pentaglottis sempervirens) is a vigorous, blue-flowered perennial with contrasting white 'eyes', native to south-west Europe.How To Identify Green... · Plants That Green Alkanet... · Should I Remove Green...
[69]
Green Alkanet - Washington State Noxious Weed Control Board
Pentaglottis sempervirens. Green Alkanet. Family: Boraginaceae. Other Common Names: evergreen bugloss, evergreen alkanet. Weed class: C
[70]
Green alkanet identification and control - King County, Washington
Green alkanet is known as Pentaglottis sempervirens and it is in the forget-me-not family. It is also known as evergreen bugloss or evergreen alkanet. Its ...
[71]
Alkanna - an overview | ScienceDirect Topics
Alkanna is defined as the dried root of Alkanna tinctoria, a herb from the Boraginaceae family, known for its reddish-purple color and used for coloring oils, ...
[72]
Alkanna orientalis (L.) Boiss. | Plants of the World Online
The native range of this species is S. & E. Medit. to W. & Central Iran. It is a perennial and grows primarily in the temperate biome.
[73]
Phytochemical Profiling and Biological Assessment of the ... - NIH
Jan 17, 2024 · This study focuses on the phytochemical analysis of the aerial parts of three Alkanna species: A. orientalis (L.) Boiss., A. tinctoria Tausch.<|control11|><|separator|>
[74]
[PDF] Economic and ecological importance of Alkanna Orientalis Var ...
Dec 25, 2021 · Habitat and ecological characteristics of Alkanna orientalis ... Distribution of Alkanna orientalis' biodiversity services and functions.
[75]
Alkanna strigosa Boiss. & Hohen. - Plants of the World Online
The native range of this species is W. Syria to Sinai. It is a perennial and grows primarily in the subtropical biome.
[76]
Alkanna strigosa Boiss. & Hohen. | Flora of Israel and adjuscent areas
Characteristics and identification. Plant Structure; Flowering and Reproduction; Leaf Arrangement; Habitat; Global Distribution. Life form (Raunkiaer): ...
[77]
Alkanna strigosa - Uses, Benefits & Common Names - Selina Wamucii
Alkanna strigosa (also called strigose alkanet, among many other common names) is an evergreen subshrub with a woody base and a rosette of leaves.
[78]
Spatial and ecological drivers of population structure in Alkanna ...
May 6, 2021 · This suggests that both species share the same ploidy. These results are the first reported for A. tinctoria and A. sieberi. Within the genus, ...<|control11|><|separator|>
[79]
https://pdfs.semanticscholar.org/e6c3/d45f6758d4cc979fa6bbee5478fae7e4ac77.pdf
[80]
Alkanna - Plant List
Alkanna tinctoria (L.) Tausch; Flora 7: 234 (1824). subspecies : subsp ... [Linnaeus] 1: 132 (1753). = Lycopsis cyrenaica Spreng.; Syst. Veg., ed. 16 ...
[81]
[PDF] 1997 IUCN red list of threatened plants - Internet Archive
... Alkanna noneiformis Griseb. 20171. R. Pseudobombax tomentosum (Mart. & Zucc ... cappadocica Boiss. & Bal. 12840. E 8 t as x Moria 2085). R. 12840 Turkey ...