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Mucor

Mucor is a genus of approximately 50 species of fast-growing molds belonging to the phylum Mucoromycota, order Mucorales, and family Mucoraceae.^[1] These fungi are characterized by coenocytic (aseptate or irregularly septate) hyphae forming fine, branching threads, and asexual reproduction via upright sporangiophores topped with globose sporangia containing numerous non-motile sporangiospores; sexual reproduction occurs through zygospores formed by gametangial fusion.^[2]^[3] Primarily saprotrophic, species of Mucor are ubiquitous worldwide, colonizing moist soils, dung, decaying plant and animal matter, and other organic substrates, where they play a crucial role in decomposition and nutrient cycling.^[3]^[2] Notable species include Mucor circinelloides, M. racemosus, and M. hiemalis, which together represent a significant portion of the genus's diversity.^[3] Economically, certain Mucor species contribute to food fermentation processes, such as mold-ripened cheeses, while others serve as model organisms in genetic and biotechnological research due to their dimorphic growth and metabolic versatility.^[3] Medically, Mucor ranks among the leading causes of mucormycosis, a life-threatening opportunistic infection affecting immunocompromised individuals through inhalation or ingestion of spores.^[4]

Taxonomy

Etymology and History

The genus name Mucor derives from the Latin word mucor, meaning "moldiness" or "mustiness," a term that aptly describes the slimy, mold-like growth observed in early examinations of these fungi.^[5] The genus was first formally described by Pier Antonio Micheli in 1729, in his pioneering work Nova plantarum genera, where he provided detailed illustrations of the sporangia characteristic of Mucor mucedo, marking one of the earliest scientific depictions of fungal reproductive structures.^[6] Carl Linnaeus later incorporated the genus into binomial nomenclature in the second edition of Species Plantarum in 1753, designating M. mucedo as the type species and grouping it among broader categories of molds.^[7] Christiaan Hendrik Persoon further advanced its taxonomic recognition in 1801 through Synopsis Methodica Fungorum, adopting and refining names from prior works to establish a systematic framework for fungi, including Mucor.^[8] Initially, Mucor species were classified within loose assemblages of molds and included in the broader group that would later become known as Zygomycetes.^[9] The concept of the genus evolved significantly during the 19th and early 20th centuries through contributions from mycologists; notably, in 1892, Eduard Fischer established the family Mucoraceae in his classification of the order Mucorales, distinguishing it based on sporangial and zygospore characteristics.^[10] Early species descriptions focused on morphological traits, with M. mucedo serving as the foundational example, reflecting growing interest in their diversity.^[11]

Phylogenetic Classification

Mucor is a genus of fungi classified in the family Mucoraceae, within the order Mucorales, subphylum Mucoromycotina, and phylum Mucoromycota.^[12] This placement reflects its position among the early-diverging lineages of true fungi, distinct from the more derived Ascomycota and Basidiomycota that form the subkingdom Dikarya.^[13] Prior to 2018, Mucor and related genera were grouped under the polyphyletic phylum Zygomycota, but genome-scale phylogenetic analyses led to the establishment of Mucoromycota as a monophyletic phylum, separating it from other zygomycetous groups like Zoopagomycota.^[13] Phylogenetically, Mucor occupies a basal position relative to Dikarya, supported by multi-gene studies incorporating ribosomal DNA regions such as SSU rDNA and ITS, along with protein-coding genes like RPB1.^[14] These analyses highlight the ancient divergence of Mucoromycota, estimated to have occurred over 800 million years ago, underscoring the genus's role in understanding early fungal evolution. The order Mucorales, including Mucor, forms a well-supported clade within Mucoromycotina, characterized by zygosporic reproduction and saprotrophic lifestyles.^[3] Recent advancements in phylogenomics have driven ongoing taxonomic revisions in Mucor, with numerous new species described between 2020 and 2025 using multi-locus sequence data and whole-genome approaches.^[15] For species delimitation, key molecular markers include the internal transcribed spacer (ITS), large subunit (LSU) rDNA, and translation elongation factor 1-α (EF1-α), which have proven effective in resolving relationships and identifying cryptic diversity.^[16] For instance, analyses of the Mucor circinelloides complex have delineated multiple cryptic species through these markers, revealing hidden genetic variation with clinical implications.^[16]

Morphology and Growth

Macroscopic Features

Mucor species exhibit rapid colonial growth on standard mycological media such as potato dextrose agar (PDA) or malt extract agar (MEA), typically covering the entire Petri dish within 2 to 5 days at optimal temperatures of 25–30°C.^[17] Colonies initially appear white and fluffy or cottony due to abundant aerial mycelium, which fills the airspace above the agar surface.^[18] As cultures mature and sporulation occurs, the colony surface often darkens to gray, yellow, beige, or black shades, reflecting the production of sporangiospores.^[18] Growth is favored under conditions of high water activity (a_w > 0.90), with radial expansion rates exceeding 6 mm per day for most species at optimal moisture levels.^[19] Optimal temperatures range from 20–30°C, though some thermotolerant species, such as Mucor miehei, can extend growth up to 45°C.^[20] The reverse side of colonies remains colorless or pale (tan to yellow), and a musty odor is commonly produced during active growth.^[21] While primarily manifesting as filamentous hyphal growth in vitro, certain Mucor species display dimorphic behavior, shifting to yeast-like forms in vivo or under physiological stress such as elevated temperatures or anaerobic conditions with high CO_2.^[22] This transition, observed in species like Mucor circinelloides, underscores the fungus's adaptability but does not alter its predominant filamentous colony morphology in standard culture.^[23]

Microscopic Structures

The hyphae of Mucor species are coenocytic, meaning they lack septa or possess only sparse septations, forming a continuous multinucleate cytoplasmic mass that facilitates rapid nutrient transport and growth. These hyphae are broad, typically measuring 5-15 μm in diameter, with thin walls and irregular, often right-angled branching patterns that contribute to the fungus's invasive growth in substrates.^[24]^[25] Under microscopic examination, the hyphae appear ribbon-like and hyaline, reflecting their translucent, non-pigmented nature, and they exhibit no clamp connections, distinguishing Mucor from basidiomycete fungi.^[26] Sporangiophores in Mucor are erect structures arising directly from the hyphae, usually unbranched or with sparse branching, and they terminate in sporangia without the presence of rhizoids or apophyses at their bases. These sporangiophores can extend up to several millimeters in length and are hyaline, tapering slightly toward the apex, which supports efficient spore dispersal.^[27]^[12] The absence of rhizoids—root-like anchoring hyphae—and apophyses—swollen regions beneath the sporangium—serves as a key diagnostic feature in microscopic identification of the genus.^[28] The cell walls of Mucor hyphae are primarily composed of chitin and chitosan, polysaccharides that provide structural rigidity and flexibility, with chitosan being particularly abundant in Mucorales compared to other fungal groups. This chitin-chitosan matrix is visualized effectively through staining with lactophenol cotton blue, which binds to the polysaccharides and imparts a blue coloration to the hyphae, aiding in clear delineation of their aseptate morphology under light microscopy.^[29]^[30] Cytologically, the coenocytic hyphae of Mucor contain multiple nuclei distributed throughout the cytoplasm, enabling coordinated cellular functions without compartmentalization. A notable feature is the rapid bidirectional cytoplasmic streaming observed in the hyphal tips and along the length, driven by cytoskeletal elements, which transports organelles, vesicles, and nutrients at speeds up to several micrometers per second, supporting the fungus's fast colonization of environments.^[31]

Reproduction

Asexual Reproduction

Asexual reproduction in Mucor species primarily occurs through the formation and dispersal of sporangiospores, enabling rapid propagation in suitable environments. The process begins with the development of erect or branched sporangiophores arising from the haploid mycelium, which terminate in a globose sporangium typically measuring 50-300 μm in diameter.^[1] Each sporangium contains a prominent columella, a dome-shaped or hemispherical structure that supports the spore mass and becomes visible as a collarette after spore release.^[1] Inside the sporangium, numerous sporangiospores form, which are unicellular, non-motile, and measure 3-10 μm in length; these spores are typically angular to subglobose or ellipsoidal in shape and range from hyaline to grey or brownish in color.^[1]^[32] Upon maturation, the sporangial wall undergoes deliquescence, dissolving to release the sporangiospores, which are then dispersed primarily by air currents to facilitate colonization of new substrates.^[32] This dispersal mechanism is crucial for the fungus's saprophytic lifestyle, allowing efficient spread across moist, nutrient-rich organic matter such as decaying plant material or soil.^[1] The reproductive cycle remains haploid throughout, with no meiosis involved in sporangiospore production; instead, the spores germinate directly under favorable conditions by extending a germ tube that develops into new mycelium. Germination requires moisture and available nutrients to initiate hyphal growth, typically occurring in environments with high humidity and organic substrates.^[33] Sporulation in Mucor is triggered by environmental cues such as high humidity, nutrient limitation, and other stresses, which promote the differentiation of sporangiophores and sporangia formation.^[34] In some species, chlamydospores—thick-walled, resting structures formed intercalary or terminal on hyphae—serve as an additional survival mechanism during periods of stress, such as desiccation or nutrient scarcity, allowing the fungus to endure until conditions improve for renewed growth.^[1] These adaptations underscore Mucor's opportunistic nature, enabling quick responses to transient ecological niches.^[12]

Sexual Reproduction

Sexual reproduction in Mucor is relatively rare compared to asexual propagation and typically occurs under unfavorable environmental conditions, serving as a mechanism for survival and genetic diversification. Most species exhibit heterothallism, requiring compatible strains of opposite mating types (+ and -) to initiate the process, although some species are homothallic, capable of self-fertilization within a single thallus.^[35]^[36] Compatible hyphae must come into physical contact for mating to proceed, often triggered by nutrient depletion, desiccation, or other stresses that signal the need for a dormant phase.^[37]^[38] The sexual cycle begins with the fusion of gametangia—specialized, multinucleate structures formed at the tips of compatible hyphae from opposite mating types. This fusion produces a zygosporangium, a multinucleate sac that develops into one or more thick-walled zygospores within it. Zygospores are typically black or dark brown, typically measuring 20–100 μm in diameter, and feature ornamented walls that may be warty, spiny, or smooth depending on the species; they are often heterokaryotic, containing multiple haploid nuclei from both parents before karyogamy occurs.^[37]^[12] In some cases, such as Mucor mucedo, the zygosporangia and mature zygospores appear as dark specks visible to the naked eye when produced in abundance.^[35] Upon exposure to favorable conditions after a period of dormancy lasting months to years, zygospores germinate through meiosis, producing a promycelium (germ hypha) that bears a sporangium filled with haploid meiospores. These meiospores can then germinate to form new mycelia, potentially of recombinant genotypes due to genetic recombination during meiosis, thereby enhancing adaptability and diversity in the population. The thick, resistant walls of zygospores provide protection against harsh conditions, functioning as resting structures that ensure species persistence in variable environments.^[35]^[37]

Ecology and Distribution

Habitats

Mucor species are predominantly saprophytic fungi that inhabit a range of decaying organic substrates, serving as key decomposers in natural ecosystems. They are commonly isolated from dead plant material, including fruits, vegetables, and plant debris, where they break down complex organic compounds into simpler nutrients. Additionally, Mucor thrives on animal dung and manure, contributing to nutrient cycling in terrestrial environments. These fungi are ubiquitous in soil, particularly in environments rich in organic matter, and have been frequently recovered from such substrates worldwide.^[39]^[40]^[3] As saprophytes, Mucor species play a vital ecological role in decomposition processes, facilitating the recycling of nutrients from organic waste back into the ecosystem. While primarily free-living decomposers, some Mucor taxa act as occasional endophytes within plants, colonizing internal tissues without causing apparent harm and potentially aiding host tolerance to environmental stresses like heavy metals. Certain species also form associations with insects, such as crickets. These interactions highlight Mucor's adaptability in diverse biotic niches.^[40]^[41]^[42]^[43] Mucor preferentially occupies high-moisture microhabitats, including compost heaps, grain silos, and aquatic sediments, where organic matter accumulates. These fungi exhibit tolerance to low oxygen levels, enabling growth in anaerobic or semi-anaerobic conditions common in waterlogged soils or submerged debris. In agricultural settings, Mucor competes with bacterial decomposers for resources on decaying matter and is notorious for causing post-harvest rots in stored fruits and vegetables, leading to significant economic losses.^[39]^[44]^[45]^[46]

Global Distribution

Mucor is a cosmopolitan genus of fungi with a worldwide distribution, occurring on all continents, including Antarctica where cold-adapted strains such as Mucor psychrophilus have been documented in icy habitats.^[47]^[48] Its broad adaptability across diverse environments, from polar regions to equatorial zones.^[49] The geographic spread of Mucor is primarily driven by airborne dispersal of its spores, which allows for long-distance transport via wind currents, and by human activities such as international trade in fruits, vegetables, and soil-containing materials where the fungus frequently colonizes decaying organic matter.^[50]^[51] While Mucor species exhibit higher prevalence in tropical and subtropical regions—owing to their preference for warm, humid conditions—they demonstrate remarkable adaptability to temperate climates, enabling establishment in cooler soils and vegetation worldwide.^[52] Regional patterns reveal elevated species diversity in Asia, particularly in China and India, where recent isolations and discoveries have highlighted novel strains in soil and plant substrates.^[53]^[54] In contrast, Mucor is commonly reported in the soils of Europe and North America, contributing to its ubiquitous presence in these temperate areas without regional dominance.^[55] Climate plays a key role in distribution, with most species thriving in warm, humid environments that support rapid growth and sporulation, while psychrophilic variants persist in cold regions like high altitudes and polar zones.^[56]^[57]

Clinical Significance

Mucormycosis

Mucormycosis, also known as zygomycosis, is a severe, opportunistic fungal infection primarily caused by species within the order Mucorales, including Mucor, that affects immunocompromised individuals.^[25] The disease arises from the inhalation, ingestion, or direct inoculation of fungal spores, leading to rapid tissue invasion and high mortality if untreated.^[58] It is particularly aggressive due to the fungus's ability to evade host defenses in vulnerable hosts, such as those with diabetes or neutropenia.^[59]

Pathogenesis

The pathogenesis of mucormycosis involves angioinvasive growth, where inhaled or ingested spores germinate in host tissues, particularly in acidic or iron-rich environments that favor fungal proliferation.^[60] The resulting hyphae, which are broad (10-20 μm in diameter), ribbon-like, and either aseptate or pauciseptate with right-angle (90°) branching, penetrate blood vessel walls, inducing endothelial damage.^[25] This invasion triggers thrombosis, ischemia, and subsequent tissue necrosis, creating a nidus for further fungal dissemination and contributing to the disease's fulminant course.^[58] Mucor species express virulence factors like CotH proteins that bind to host integrins, facilitating epithelial adhesion and invasion.^[60]

Clinical Forms

Mucormycosis manifests in several clinical forms, with rhinocerebral being the most common, accounting for approximately 40% of cases, followed by pulmonary, cutaneous, gastrointestinal, and disseminated types.^[4] In the rhinocerebral form, infection typically begins in the paranasal sinuses and extends to the orbit or brain, presenting with symptoms such as facial pain, swelling, nasal congestion, and a characteristic black eschar over the palate or nasal mucosa.^[61] Pulmonary mucormycosis often occurs in neutropenic patients and features fever, cough, hemoptysis, and dyspnea, potentially progressing to cavitary lesions or acute respiratory failure.^[25] Cutaneous involvement results from traumatic inoculation, leading to necrotic ulcers with indurated borders, while gastrointestinal cases cause abdominal pain, bleeding, and perforation; disseminated disease involves multiple organs and is associated with fever and multi-organ failure.^[61]

Diagnosis

Diagnosis of mucormycosis relies on a combination of clinical suspicion, imaging, and direct microbiological confirmation, as early detection is critical for improving outcomes.^[62] Biopsy of affected tissue reveals the pathognomonic broad, non-septate hyphae with 90° branching under histopathology, often confirmed with special stains like Grocott-Gomori methenamine silver.^[25] Fungal culture from biopsies or fluids identifies Mucor species, though it may take days and has variable sensitivity.^[4] Molecular methods, including PCR assays targeting Mucorales-specific genes, provide rapid identification; as of 2024, commercial quantitative PCR (qPCR) kits for Mucorales detection are available, enhancing diagnostic speed and accuracy.^[4]^[63]^[62] Imaging such as CT or MRI demonstrates tissue infarction, sinus opacification, or reverse halo signs in pulmonary cases.^[4]^[62]

Treatment

Treatment of mucormycosis requires a multimodal approach, emphasizing prompt surgical intervention combined with systemic antifungal therapy to address the angioinvasive nature of the infection.^[64] Aggressive surgical debridement of necrotic tissue is essential to remove the fungal burden and improve antifungal penetration, often repeated as needed.^[65] First-line antifungal therapy involves liposomal amphotericin B (5-10 mg/kg/day intravenously), which exhibits broad activity against Mucorales, with salvage options including posaconazole or isavuconazole for those intolerant or refractory to amphotericin.^[64]^[66] Emerging investigational immunotherapies targeting host immune responses are under development as of 2025, potentially offering adjunctive options for refractory cases.^[67] Adjunctive measures, such as reversing underlying risk factors (e.g., hyperglycemia control), enhance efficacy, though overall mortality remains high at 50-90%, varying by site and host factors, with disseminated forms carrying the worst prognosis.^[68]^[62]

Epidemiology and Risk Factors

Mucormycosis, the primary clinical manifestation of Mucor infections, remains a rare opportunistic fungal disease with a global incidence ranging from 0.005 to 1.7 cases per million population annually. In high-burden regions such as India, the prevalence is notably higher, estimated at 140 cases per million population, reflecting underlying predisposing factors like uncontrolled diabetes. Mucor species account for approximately 10-20% of all mucormycosis cases, with Rhizopus species being more predominant; however, post-COVID-19 surges—primarily during 2020-2022, with cases declining thereafter—have highlighted Mucor as a significant contributor, particularly in diabetic patients, where cases rose dramatically in India and other parts of Asia.^[69]^[70]^[71]^[72] Transmission of Mucor infections occurs primarily through inhalation or ingestion of ubiquitous environmental spores, which are widespread in soil, decaying vegetation, and organic matter. Nosocomial acquisition is also documented, often via contaminated medical devices, bandages, or hospital linens, leading to outbreaks in healthcare settings. Cutaneous infections, comprising about 10-20% of cases, frequently arise from direct inoculation during trauma or surgery involving soil exposure, emphasizing the role of environmental reservoirs in infection dynamics.^[73]^[4]^[74] Key risk factors for Mucor-associated mucormycosis center on host immunocompromise, including uncontrolled diabetes with ketoacidosis, which impairs neutrophil function and promotes fungal angioinvasion. Neutropenia, often seen in hematologic malignancies or chemotherapy, increases susceptibility by limiting innate immune defenses, while solid organ or hematopoietic stem cell transplants elevate risk due to immunosuppressive regimens. Additional vulnerabilities include iron overload states, such as hemochromatosis or deferoxamine therapy, which facilitate Mucor growth by enhancing spore germination, and prolonged corticosteroid use, which further suppresses phagocytosis. Recent trends indicate a rising incidence in Asia, driven by increasing diabetes prevalence and COVID-19-related corticosteroid administration, with outbreaks linked to soil-contaminated wounds in agricultural workers.^[75]^[76]^[77]^[78]

Species

Diversity and Number

The genus Mucor currently encompasses approximately 133–137 accepted species, reflecting a significant expansion driven by molecular taxonomic approaches in recent years. As of mid-2025, the Catalogue of Life lists 133 species, while a September 2025 study describing four new species from Chinese soils elevated the total to 137. This rapid increase is evidenced by over 45 new species descriptions between 2020 and 2025, primarily resulting from multilocus phylogenetic analyses that have resolved previously unrecognized taxa.^[79]^[80] Biodiversity within Mucor is largely propelled by cryptic speciation within species complexes and adaptations to specialized habitats. For instance, the M. circinelloides complex has revealed multiple cryptic sibling species through genomic and mating-type analyses, highlighting hidden diversity that morphological traits alone cannot distinguish. Habitat specialization further contributes, with many species exhibiting preferences for soil versus coprophilous (dung-associated) niches; examples include soil-endemic taxa like M. thermorhizoides and dung-specialized ones such as M. mucedo, which underscore ecological partitioning as a driver of speciation.^[81]^[82] Identification of Mucor species remains challenging due to high morphological similarity among taxa, often requiring multilocus sequencing for accurate delineation. Sporangiophore structure, sporangiospore size, and chlamydospore presence provide limited diagnostic value, as overlapping traits confound traditional microscopy-based methods. Consequently, reliance on genetic markers such as ITS rDNA, combined with additional loci like EF1-α and RPB2, has become standard for resolving cryptic diversity and confirming novel species.^[83]^[84] Conservation assessments are not applicable to Mucor species, as the majority are cosmopolitan saprobes thriving in ubiquitous environments like soil, decaying vegetation, and organic waste, with no known endangered taxa.^[85]

Selected Species

Mucor circinelloides is a prominent species within the genus, recognized as a common opportunistic pathogen capable of causing mucormycosis, including pulmonary infections. This thermotolerant fungus exhibits dimorphic growth, transitioning between filamentous and yeast-like forms, which contributes to its pathogenicity in immunocompromised hosts. It has a worldwide distribution in soil and decaying organic matter, and is notable for its synonyms, including M. lusitanicus.^[86] Mucor racemosus is frequently implicated in food spoilage, particularly in postharvest decay of fruits and vegetables, as well as contamination in silage, where it leads to nutrient loss and mycotoxin production. Its distinguishing morphological trait includes clustered or branched sporangiophores bearing globose sporangia, resulting in fluffy, greyish colonies that grow rapidly under aerobic conditions. This species is ubiquitous in damp environments and plays a role in agricultural losses due to its saprophytic nature.^[87]^[88] Formerly known as M. rouxii, Mucor indicus holds industrial significance, particularly in the fermentation of tempeh, an Indonesian soy-based food, where it contributes to protein enrichment and flavor development. As a dimorphic fungus, it is utilized in biotechnology for producing ethanol, oils, and glucosamine from various substrates. Additionally, it acts as an opportunistic pathogen, occasionally causing infections in diabetic patients, highlighting its dual role in food production and clinical contexts.^[89]^[90] Mucor irregularis has emerged as a significant pathogen, primarily associated with chronic cutaneous mucormycosis in Asia, especially China, where it causes localized skin infections that can be disfiguring or invasive in immunocompetent individuals. Unlike other Mucor species, it often presents with irregular sporangiophores and is geographically concentrated, with over 90% of cases reported from Asian regions. Its increasing recognition underscores the need for molecular identification in clinical diagnostics.^[53]^[54] Among other notable species, Mucor amphibiorum is a specialized pathogen affecting amphibians and platypuses, causing ulcerative dermatitis and systemic infections in wildlife, particularly in Australia and Tasmania. Mucor mucedo, known as the common pinmould, is a widespread saprophyte found on dung, soil, and decaying fruits, often appearing as white, fluffy growths but rarely pathogenic. Recently described Mucor xinjiangensis represents a novel plant pathogen, responsible for brown rot disease in plums in China's Xinjiang region, illustrating ongoing discoveries in Mucor diversity.^[91]^[92]

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During unfavourable condition, thick-walled, nutrition rich ... It is, however, haploid in nature and its nucleus does not undergo meiosis before spore formation.Missing: tube moist
[39]
Biotic Environments Supporting the Persistence of Clinically ...
Dec 20, 2019 · Clinically relevant members of the Mucorales group can grow and are found in diverse ecological spaces such as soil, dust, water, decomposing vegetation, on ...
[40]
DNA barcoding in Mucorales: an inventory of biodiversity - PMC
The order Mucorales represents a phylogenetically ancient group of fungi comprising predominantly saprotrophs inhabiting soil, dung and dead plant material, as ...Missing: ecological | Show results with:ecological
[41]
Mucor sp.-An endophyte of Brassicaceae capable of surviving in ...
Mucor sp. was shown to be highly tolerant to elevated levels of Zn, Cd, and Pb and to accelerate plant-host growth under either toxic-metal stress or ...
[42]
Endophytic fungus Mucor circinelloides DF20 promote tanshinone ...
Symbiosis of endophytic fungi with their host plants, is an effectively regulatory means to promote the growth and secondary metabolism of medicinal plants.
[43]
Discovery of Three New Mucor Species Associated with Cricket ...
The aim of this study was to characterize three new species of Mucor: Mucor grylli sp. nov., M. hyangburmii sp. nov., and M. kunryangriensis sp. nov., ...
[44]
Mucor germinans, a novel dimorphic species resembling ...
Jul 2, 2024 · Description: Colonies on SGA attain a diameter of 80–86 mm after 4 days at 28°C, at first white and then becomes yellowish brown; colony reverse ...Missing: macroscopic | Show results with:macroscopic
[45]
Home Gardening: Mucor Rot - Penn State Extension
Jun 21, 2023 · Mucor rot develops at the calyx end of fruit or at wound punctures in the skin. Infected fruit completely decay after about two months in cold storage.Missing: dung compost
[46]
Apple and Pear Disease - Mucor Rot - Penn State Extension
Apr 8, 2023 · Mucor rot develops at the calyx end of fruit or at wound punctures in the skin. Infected fruit completely decay after about two months in cold storage.Missing: dung compost
[47]
Mucor - an overview | ScienceDirect Topics
Mucor is a fungal genus classified in the Mucorales, the most prominent order of zygospore-forming fungi that formerly constituted the Zygomycota, a phylum ...
[48]
Adaptation of the psychrophilic Mucor psychrophilus (Mucorales ...
They are eurytopic fungi that are found everywhere, from hot regions of Asia and Latin America (Nguyen et al., 2024) to cold habitats of Antarctica (Martorell ...
[49]
Novel Mucor species (Mucoromycetes, Mucoraceae) from northern ...
Nov 1, 2021 · Mucor is the most species-rich genus within Mucorales commonly found in soil and dung. Its species comprise mainly saprobes, but also endophytes ...Missing: authority | Show results with:authority
[50]
Pathogenicity patterns of mucormycosis: epidemiology, interaction ...
Feb 28, 2019 · ... mucoralean fungi. Spores are dispersed by air and taken up by humans via inhalation or ingestion of contaminated food, even though ...Missing: trade | Show results with:trade
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Impact of global megatrends on the spread of microscopic fungi in ...
Global megatrends have major impacts on microscopic fungi. Many fungi are imported with tropical fruits, soil and packaging materials.
[52]
Review Mucormycosis: an emerging disease? - ScienceDirect.com
Mucormycosis most commonly manifests in the sinuses (39%), lungs (24%), skin (19%), brain (9%), and gastrointestinal tract (7%), in the form of disseminated ...Missing: prevalence | Show results with:prevalence
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Taxonomy and epidemiology of Mucor irregularis, agent of chronic ...
Macroscopic and microscopic morphology of Mucor irregularis. a. Colony on MEA after 4 days incubation at 30 °C; b. colony from backside; c, d, f–k.
[54]
The influence of the mating type on virulence of Mucor irregularis
Sep 6, 2017 · Our findings support the involvement of MAT genes in sexual fertility, and the influence of mating type on the severity of cutaneous infection.
[55]
Novel Mucor species (Mucoromycetes, Mucoraceae) from northern ...
Nov 1, 2021 · Mucor aseptatophorus has smaller sporangiospores (3.5–5 × 2–2.5 µm), slightly bigger sporangia, forms sympodial, and monopodial branching of ...<|control11|><|separator|>
[56]
[PDF] fungal descriptions assured bio labs
Aspergillus flavus is a mold that thrives in warm, humid indoor environments ... Mucor species are commonly found in soils and terrestrial environments.
[57]
Adaptation of the psychrophilic Mucor psychrophilus (Mucorales ...
Aug 4, 2025 · To adapt to cold environments, such as the Arctic and Antarctic regions, high mountain peaks, cold soils, deserts, caverns, and cryopegs ...
[58]
Pathogenesis of Mucormycosis - PMC - PubMed Central
Mucormycosis infections are characterized by extensive angioinvasion that results in vessel thrombosis and subsequent tissue necrosis [3, 6, 43]. Ischemic ...
[59]
Pathogenesis of mucormycosis - PubMed - NIH
Mucormycosis is a life-threatening infection that occurs in patients who are immunocompromised because of diabetic ketoacidosis, neutropenia, ...
[60]
Mucormycosis in 2023: an update on pathogenesis and management
Mucorales fungi can reproduce through both sexual and asexual means. Asexual reproduction involves the formation of spherical structures called sporangiospores, ...
[61]
Epidemiology and clinical manifestations of mucormycosis - PubMed
Based on anatomic localization, mucormycosis can be classified as one of 6 forms: (1) rhinocerebral, (2) pulmonary, (3) cutaneous, (4) gastrointestinal, (5) ...
[62]
Global guideline for the diagnosis and management of mucormycosis
Mucormycosis is a difficult to diagnose rare disease with high morbidity and mortality. Diagnosis is often delayed, and disease tends to progress rapidly.
[63]
Treatment of Mucormycosis - CDC
Apr 24, 2024 · Mucormycosis is a serious infection and needs to be treated with prescription antifungal medication right away. The most common antifungals used ...
[64]
Current treatments against mucormycosis and future directions - PMC
Oct 13, 2022 · AMB, isavuconazole, and posaconazole, and the surgical debridement of necrotic tissue when necessary are the most common practices in treating mucormycosis.What Are The Currently... · Amphotericin B And Its Lipid... · Fig 1. Diagram Representing...
[65]
Global guideline for the diagnosis and management of mucormycosis
First-line treatment with high-dose liposomal amphotericin B is strongly recommended, while intravenous isavuconazole and intravenous or delayed release tablet ...<|control11|><|separator|>
[66]
Data and Statistics on Mucormycosis - CDC
Apr 24, 2024 · Deaths due to mucormycosis. Depending on the patient and body site(s) affected, mucormycosis may be associated with >50% mortality rate. During ...
[67]
Mucormycosis - World Health Organization (WHO)
Clinical presentation is classified according to the organ involvement. It can be rhino-orbital cerebral, pulmonary, cutaneous, gastrointestinal, or ...Disease Burden · Symptoms · Treatment<|separator|>
[68]
Global Epidemiology of Mucormycosis - PMC - PubMed Central
Mar 21, 2019 · Rhizopus arrhizus is the most common agent causing mucormycosis across the globe, followed by Lichtheimia, Apophysomyces, Rhizomucor, Mucor and ...
[69]
Surge of mucormycosis during the COVID-19 pandemic
Based on the clinical context, the major genera include Rhizopus (47%), Mucor (18%), Cunninghamella (7%), Saksenaea (5%), Absidia (5%), Apophysomyces (5%), and ...
[70]
Mucormycosis Basics - CDC
Apr 24, 2024 · It can affect sinuses, brain, lungs, skin, stomach and intestines, or cause symptoms throughout the body. Mucormycosis most commonly affects the ...
[71]
Healthcare-Associated Mucormycosis | Clinical Infectious Diseases
Mucormycosis is a severe emerging invasive fungal infection that occurs as a consequence of environmental exposure. We exhaustively reviewed all the cases of ...
[72]
Mucormycosis Risk Factors - CDC
Apr 24, 2024 · Cancer. Neutropenia (low number of white blood cells). Too much iron in the body (iron overload or hemochromatosis).
[73]
Mucormycosis: risk factors, diagnosis, treatments, and challenges ...
Immunocompetent host. In India, 3–26% of mucormycosis cases have been recorded from the immunocompetent host, compared to 18–19% globally (Jeong et al. 2019; ...
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Pathogenesis of Mucormycosis | Clinical Infectious Diseases
The major risk factors for mucormycosis include uncontrolled diabetes ... iron overload in the pathogenesis. ,. Bone Marrow Transplant. ,. 1999. , vol. 24.
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Rampant Increase in Cases of Mucormycosis in India and Pakistan
A spike in the number of mucormycosis cases in India and Pakistan has been reported in COVID-19 patients and in those who have recovered from COVID-19.
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Unveiling Species Diversity within Early-Diverging Fungi from China IX
Aug 18, 2025 · Currently, 133 species are accepted (https://www.catalogueoflife.org/, accessed on 30 June 2025). During the investigation of soil fungal ...
[77]
Unveiling Species Diversity Within Early-Diverging Fungi from China ...
Sep 21, 2025 · The aim of this study was to characterize three new species of Mucor: Mucor grylli sp. nov., M. hyangburmii sp. nov., and M. kunryangriensis ...
[78]
(PDF) A Revised Species Concept for Opportunistic Mucor Species ...
May 31, 2025 · Recently, the species concept of opportunistic Mucor circinelloides and its relatives has been revised, resulting in the recognition of its ...<|control11|><|separator|>
[79]
Mucor thermorhizoides—A New Species from Post-mining Site in ...
Jun 1, 2024 · New species Mucor thermorhizoides Abramczyk (Mucorales, Mucoromycota) is characterized by the extensive rhizoid production in elevated temperatures.
[80]
Mucor mucedo - Wikipedia
Donate Now If Wikipedia is useful to you, please give today. About Wikipedia · Disclaimers.Missing: "-britannica" | Show results with:"-britannica"
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(PDF) Identification of Mucorales From Clinical Specimens: A 4-Year ...
Aug 6, 2025 · Phenotypic differentiation and identification of Mucorales is difficult because different Mucorales share similar morphology. Our results ...
[82]
Species identification of Aspergillus, Fusarium and Mucorales with ...
As a reference method for species designation, multilocus sequencing was used. Eighty-five isolates were unequivocally identified to the species level (≥99% ...
[83]
Updates on the Taxonomy of Mucorales with an Emphasis ... - MDPI
The order Mucorales has now been assigned to the phylum Mucoromycota and is comprised of 261 species in 55 genera. Of these accepted species, 38 have been ...
[84]
A new species concept for the clinically relevant Mucor circinelloides ...
Mucor species are common soil fungi but also known as agents of human infections (mucormycosis) and used in food production and biotechnology.Missing: cryptic | Show results with:cryptic
[85]
Mucor racemosus - an overview | ScienceDirect Topics
Mucor racemosus is defined as a widely distributed pin mould species found on various damp materials, characterized by grey or brownish-grey colonies, simple ...Missing: spoiler | Show results with:spoiler
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Fungi and mycotoxins in silage: an overview - Wiley Online Library
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[87]
Mucor indicus: biology and industrial application perspectives
The effects of switching morphology and replacing supplementary nutrients with fungal extract on the production of major metabolites and chitosan by Mucor ...
[88]
Microbiological Quality of Commercial Tempeh in The Netherlands
... Mucor indicus was often associated with the mycoflora of the tempeh. The reasons for the poor microbiological quality are discussed and some recommendations ...
[89]
A new brown rot disease of plum caused by Mucor xinjiangensis sp ...
Sep 9, 2024 · A novel species of Mucor was identified as the causal agent of a brown rot of Prunus domestica (European plum), widely grown in the south of Xinjiang, China.Abstract · Introduction · Results · Discussion
[90]
Mucor amphibiorum - Habitat, Health Effects and Treatment
The most studied species from the group are M. amphibiorum, an infamous pathogen of frogs and platypus, and M. indicus, which can be pathogenic to humans. These ...