PerkinElmer
PerkinElmer, Inc. was an American multinational corporation specializing in scientific instruments, diagnostics, and services for life sciences, environmental testing, and industrial applications, founded in 1937 by Richard S. Perkin and Charles W. Elmer as a precision optics firm.[1][2] Initially focused on optical design and components for astronomy and spectroscopy, the company pioneered commercial analytical tools, including the first infrared spectrophotometer in the 1940s, which launched the analytical instrument industry.[3] Over decades, PerkinElmer expanded into atomic spectroscopy, chromatography, imaging systems, and multi-omics technologies for drug discovery, biomarker detection, and health diagnostics, contributing to advancements in space exploration optics and laboratory automation.[1][4] By the 21st century, PerkinElmer had grown into a provider of end-to-end solutions for biopharma workflows, environmental compliance, and newborn screening, with products like atomic absorption spectrometers and inductively coupled plasma systems enabling precise elemental analysis.[5][6] Notable achievements included supplying optics for major scientific projects and scaling diagnostics during public health crises, though the firm faced scrutiny over operational issues in government-contracted testing labs and investigations into billing practices.[7][8] In 2023, following the sale of its applied, food, and enterprise services segments to New Mountain Capital, PerkinElmer rebranded its core life sciences and diagnostics operations as Revvity, marking a strategic pivot toward innovation in translational research and sustainable discovery.[9][10] This evolution reflected the company's adaptation from optics manufacturing to integrated health sciences solutions, while maintaining a legacy of empirical measurement tools critical for regulatory compliance and scientific validation.[4]History
Founding and Early Development (1937–1950s)
Perkin-Elmer Corporation was established on April 19, 1937, as a partnership in New York City by Richard S. Perkin and Charles W. Elmer, with an initial focus on optical design and consulting for precision instruments.[1] Perkin, a recent New York University graduate in chemical engineering and an aspiring investment banker, raised $15,000 from relatives to fund the venture, while Elmer, a head court reporter and amateur astronomer, contributed $5,000.[1][11] Their collaboration stemmed from a shared fascination with astronomy that began in the early 1930s, prompting them to import European optical equipment and apply it to custom designs.[1] Operations commenced from a Manhattan office, but manufacturing of optical components began in Jersey City, New Jersey, by 1938, reflecting rapid early growth.[1] The firm incorporated on December 13, 1939, and relocated to Norwalk, Connecticut, in 1941 to accommodate expanded production capacity.[11] During World War II, Perkin-Elmer shifted toward defense applications, producing components for airplane range finders, bombsights, and reconnaissance systems; in 1942, it became the first optical instrument manufacturer to receive the U.S. Navy's "E" award for production excellence.[1][12][11] The wartime period also spurred innovation in analytical tools, with the introduction of the company's first infrared spectrometer in 1944 and the Model 12 single-beam infrared spectrophotometer during the decade.[1][13] These efforts culminated in the Model 21 double-beam infrared spectrophotometer around 1949, which enhanced accuracy and commercial viability in spectroscopy for industrial applications like rubber manufacturing and fuel refining.[14][13] Into the 1950s, Perkin-Elmer fabricated a 33-inch Baker-Schmidt telescope for Harvard University in 1950 and began developing gas chromatographs by 1955, diversifying beyond pure optics while Charles Elmer passed away in 1954 at age 83.[1][11]Expansion into Optics and Semiconductors (1960s–1970s)
In the 1960s, Perkin-Elmer expanded its optics division through internal development and targeted acquisitions, enhancing its production of precision optical components for analytical instruments and government applications. The company introduced ultraviolet variants of its infrared spectrometers, such as the 1961 UV upgrade to the Infracord series, broadening its spectroscopic offerings reliant on advanced optical systems. This period also saw growth in laser technology, with Perkin-Elmer producing its first commercial laser model, the 5200, in 1963, applying optics to emerging photonics. A key catalyst for entry into semiconductors came in the late 1960s via a U.S. Air Force research contract for an all-optical masking system in semiconductor fabrication, utilizing Perkin-Elmer's expertise in reflective optics.[15] This contract, initiated around 1967, shifted the company from traditional optics toward photolithography tools, addressing limitations in contact and proximity printing methods that caused wafer defects. Building on this foundation, Perkin-Elmer developed the Micralign series, launching the first projection aligner in 1973—a scanning system that projected mask patterns onto wafers via reflective optics, enabling cleaner, higher-resolution patterning at scales down to 2 microns.[16] The inaugural Micralign 100 unit was sold to Texas Instruments in 1973 for $95,000 (equivalent to approximately $650,000 in 2023 dollars), marking commercial success in the integrated circuit market.[17] By separating the mask from the wafer, the technology reduced contamination and wear, facilitating denser chip designs and contributing to the scalability of semiconductor production during the 1970s. Perkin-Elmer's optics-driven innovations positioned it as a leader in early lithography equipment, with subsequent models improving throughput and resolution amid rising demand from firms like Intel and Fairchild.[18]Diversification into Laboratory Equipment and Computing (1980s)
Perkin-Elmer's computing division, stemming from the 1974 acquisition of Interdata, Inc. for $63.6 million, focused on 32-bit minicomputers and super-minicomputers suited for scientific and real-time applications.[1] By the early to mid-1980s, the Data Systems Group generated sales of $259 million annually, remaining profitable despite perceptions that it undervalued the broader corporation's stock.[19] In 1985, Perkin-Elmer restructured by spinning off the division into Concurrent Computer Corporation, retaining an 18% stake initially before selling 82% by early 1989.[1][20] Simultaneously, the company deepened its presence in laboratory equipment through advancements in analytical instruments, holding leading positions in infrared spectroscopy, atomic absorption, gas chromatography, thermal analysis, and UV-visible spectroscopy during the early 1980s.[3] Enhancements included microprocessor-controlled infrared spectrometers upgraded with robotics integration by 1985, improving automation in chemical analysis.[1] Perkin-Elmer also ventured into biotechnology instrumentation via a 1986 joint venture with Cetus Corporation to develop tools leveraging polymerase chain reaction (PCR) techniques for DNA analysis.[1] These efforts contributed to overall sales peaking at $1.3 billion in the fiscal year ending July 1985, reflecting growth across diversified segments including instruments and data systems.[1] However, by the mid-1980s, executives recognized challenges from over-diversification, prompting a $95 million restructuring charge in 1987 that resulted in the company's first annual loss of $18 million.[1][19]Restructuring and Focus Shifts (1990s–2000s)
In the early 1990s, PerkinElmer undertook divestitures of non-core operations, including the sale of its BGT subsidiary in Germany to the Diehl Group and portions of its Hughes Aircraft operations between November 1989 and May 1990, as part of efforts to streamline its portfolio amid shifting market demands.[21] By 1993, the company acquired Applied Biosystems, bolstering its capabilities in DNA sequencing and synthesis, which marked an initial pivot toward life sciences applications.[21] In 1995, under new leadership of Tony L. White as president, chairman, and CEO, PerkinElmer reorganized into two primary divisions—Analytical Instruments and Applied Biosystems—to address slow growth and mounting restructuring costs that had eroded profits.[21] Further acquisitions in 1996, including Tropix Inc., GenScope, and PerSeptive Biosystems, targeted enhancements in drug discovery, genetic analysis, and proteomics, signaling a strategic emphasis on biotechnology amid broader industry trends in genomics.[21] The mid-to-late 1990s saw intensified challenges, with persistent profitability issues prompting the appointment of Gregory L. Summe as CEO in 1998 to orchestrate a comprehensive turnaround.[21] Summe implemented aggressive portfolio rationalization, including job cuts and divestitures of underperforming units unable to achieve market leadership or double-digit growth, while communicating the strategy through regular internal "town hall" meetings to align the organization.[22] This culminated in a pivotal 1999 transaction where PerkinElmer sold its Analytical Instruments division to EG&G Inc. for $425 million, allowing EG&G to adopt the PerkinElmer name for its ongoing analytical operations; simultaneously, the life sciences assets, encompassing Applied Biosystems and the newly formed Celera Genomics, were consolidated under PE Corporation (renamed Applera Corporation in 2000), effectively splitting the company to concentrate resources on high-growth genetic and pharmaceutical tools.[23][24][21] Into the 2000s, the restructured PerkinElmer (as the entity retaining the name post-1999) executed 6 divestitures and 11 acquisitions between 1998 and 2001 under Summe's direction, transforming from a diversified supplier of government services and instruments into a focused high-technology firm oriented toward life sciences innovation.[25] Key 2000 acquisitions included NEN Life Sciences Inc. for drug discovery reagents and Packard BioScience Co. for detection technologies, alongside Elcos AG, reinforcing capabilities in genetic screening and pharmaceutical applications.[26][21] By 2005, the company planned the divestiture of its fluid sciences division to eliminate remaining non-core elements, achieving a revenue increase of 10% in 2004 and narrowing its focus exclusively to human health, diagnostics, and environmental health sectors.[21] These shifts prioritized empirical alignment with emerging markets in biotechnology and informatics, divesting low-margin operations to fund investments yielding higher returns.[22]Modern Era and Strategic Acquisitions (2010s–2020s)
In the 2010s, PerkinElmer pursued a strategic shift toward health sciences and diagnostics, divesting non-core assets such as its Illumination and Detection Solutions business to Veritas Capital for approximately $500 million in November 2010 to streamline operations and fund growth in high-potential areas.[27] This period saw key acquisitions to bolster capabilities in molecular imaging, informatics, and microfluidics, including VisEn Medical in August 2010 for in vivo imaging technologies, CambridgeSoft and ArtusLabs in March 2011 for cheminformatics software, Labtronics in May 2011 for laboratory execution systems, Geospiza in May 2011 for genomics workflows, and Caliper Life Sciences for $600 million in November 2011 to enhance lab-on-a-chip and detection solutions.[28][29][30][31] These moves expanded PerkinElmer's portfolio in drug discovery and genetic analysis, aligning with empirical demand for integrated tools in biotechnology research. The 2020s marked accelerated expansion amid the COVID-19 pandemic, where PerkinElmer's SARS-CoV-2 RT-qPCR reagent kit received FDA Emergency Use Authorization in March 2020 for nasopharyngeal swabs, later extending to saliva specimens in July 2021 and antigen point-of-care tests in February 2021, enabling high-throughput screening and contributing significantly to revenue through partnerships with labs and governments.[32][33][34] Strategic acquisitions intensified, with five major deals in 2021 alone, including BioLegend for immunology reagents and the $5.25 billion purchase of Oxford Immunotec in March 2021 for latent tuberculosis and women's health diagnostics, representing PerkinElmer's largest acquisition to date and targeting scalable assay platforms.[35][36][37] By 2022, PerkinElmer initiated a corporate restructuring to sharpen focus on high-margin segments, announcing the $2.45 billion sale of its Applied, Food, and Enterprise Services businesses to New Mountain Capital in August 2022, completed in March 2023, which allowed the diagnostics and life sciences units to rebrand as Revvity in May 2023 while retaining the PerkinElmer name for the divested applied markets operations under new ownership.[38][39][40] Post-restructuring, the New Mountain-backed PerkinElmer continued targeted buys, such as Covaris in December 2023 for sample preparation technologies and Project Farma in March 2025 for life sciences consulting services, emphasizing innovation in analytical solutions for environmental and industrial applications.[41]Products and Services
Diagnostics and Life Sciences Solutions
PerkinElmer's Diagnostics and Life Sciences Solutions division developed and commercialized technologies for early disease detection, genetic analysis, and research applications in drug discovery and biomarker identification. This segment integrated detection systems, reagents, and informatics tools to support clinical diagnostics and translational research, with a focus on reproductive health, neonatal screening, and oncology.[6][42] In diagnostics, PerkinElmer specialized in newborn screening programs, offering assays that analyzed dried blood spots collected from infants 2-5 days post-birth to detect over 70 congenital disorders, including those on the U.S. Recommended Uniform Screening Panel (RUSP). The company's StepOne screening service utilized tandem mass spectrometry and other methods for conditions like Duchenne muscular dystrophy, enabling early intervention through state pilot programs and routine testing.[43][42] Additional diagnostic offerings included genetic testing for prenatal and reproductive health, infectious disease assays, and tools for cancer biomarker detection, supported by certified service teams averaging 15 years of experience in system maintenance.[44][45] Life sciences solutions from PerkinElmer provided instrumentation and consumables for multi-omics research, including cell imaging systems, atomic spectroscopy for elemental analysis, and platforms for genomics and proteomics workflows. These tools facilitated drug discovery by enabling high-throughput screening, chemical analysis, and predictive modeling in pharmaceutical development.[6][46] The division also offered integrated services like laboratory asset management and compliance support through OneSource, targeting biopharma and research facilities to streamline operations from ideation to validation.[47] Key acquisitions bolstered this segment, such as the integration of Wallac Oy in the 2000s for advanced detection technologies like scintillation counting, enhancing capabilities in high-sensitivity bioassays. By 2022, these solutions contributed significantly to PerkinElmer's revenue through end-to-end expertise in reagents, software, and services for global research and clinical labs.[46][48]Environmental, Food, and Applied Markets Technologies
PerkinElmer's Environmental, Food, and Applied Markets Technologies division provided analytical instruments, consumables, and informatics solutions for contaminant detection, regulatory compliance, and quality assurance across these sectors.[49] The offerings included high-throughput instrumentation for environmental monitoring, food safety testing, and industrial applications, emphasizing reliable, efficient workflows.[50] In environmental analysis, PerkinElmer supplied turnkey systems for testing air, water, and soil samples, facilitating detection of persistent organic pollutants, heavy metals, and emerging contaminants. Atomic spectroscopy tools, such as inductively coupled plasma optical emission spectrometry (ICP-OES) and mass spectrometry (ICP-MS), enabled trace-level elemental analysis compliant with standards like EPA methods. These instruments supported sustainable practices through energy-efficient designs and reduced solvent use in sample preparation.[51][5] For food safety, the company manufactured test kits targeting antibiotics, hormones, veterinary drug residues, natural toxins like mycotoxins, pathogens, and industrial contaminants. The SOLUS Scientific platform utilized lateral flow immunoassays for rapid detection of key pathogens such as Salmonella, Listeria, and E. coli in food and environmental swabs, delivering results in hours to enhance supply chain efficiency. Additional solutions included enzyme-linked immunosorbent assays (ELISA) and chromatographic methods for residue screening.[52][53][54] Agriculture and food quality testing featured near-infrared (NIR) and Fourier-transform infrared (FTIR) analyzers from the Perten Instruments line, acquired by PerkinElmer, for non-destructive assessment of raw materials including grain moisture, protein, fat, and falling number. These at-line and on-line systems optimized production by minimizing waste and ensuring nutritional consistency in dairy, cereals, and feeds, while integrating contaminant checks for pesticides, allergens, and heavy metals.[55][53] Applied markets technologies extended to industrial and materials analysis, employing molecular spectroscopy (UV-Vis, FTIR, Raman) and gas/liquid chromatography for raw material verification, product quality control, and forensics. These tools supported sectors like chemicals, semiconductors, and consumer goods by quantifying impurities and ensuring material integrity.[56][5] On March 13, 2023, PerkinElmer divested its Applied, Food, and Enterprise Services businesses, including these technologies, to New Mountain Capital for $2.45 billion, allowing focus on life sciences under the Revvity rebrand.[57]Software and Informatics Platforms
PerkinElmer's software and informatics platforms encompass cloud-based suites, data management tools, and instrument-specific applications tailored for life sciences research, diagnostics, drug discovery, and laboratory operations. These solutions emphasize data integration, real-time collaboration, and workflow automation to accelerate scientific insights while ensuring compliance and scalability.[58][59] The Signals Research Suite, launched on October 26, 2021, represents a core cloud-based informatics offering deployed on Amazon Web Services, enabling secure data sharing, advanced analytics, and integration across research disciplines such as biologics and materials science. Expanded in March 2021 through acquisitions, it incorporates SnapGene for molecular biology workflows and Geneious Prime for sequence analysis, facilitating end-to-end data pipelines from experiment design to decision-making in drug discovery.[60][61] The platform supports real-time collaboration by allowing researchers to analyze vast datasets without local infrastructure constraints, with features for electronic lab notebooks and predictive modeling.[62] Complementing Signals, the OneSource Digital Platform provides laboratory informatics for operational efficiency, offering dashboards for asset utilization tracking, predictive maintenance, and resource planning to minimize downtime and optimize workflows in diagnostics and applied testing environments.[63] Instrument-specific software, such as Syngistix for inductively coupled plasma mass spectrometry (ICP-MS), delivers intuitive interfaces with real-time diagnostics, automated reporting, and compliance tools for environmental and food safety analyses.[64] In October 2021, PerkinElmer introduced a next-generation cell imaging analysis platform to streamline high-content screening in drug discovery, integrating AI-driven phenotyping and data management for faster hypothesis testing.[65] Earlier platforms like ChemBioOffice, highlighted in March 2012, combined cheminformatics tools including ChemDraw for structure drawing, Chem3D for molecular modeling, and BioViz for visualization, supporting chemical and biological R&D across pharma and biotech sectors.[66] These offerings evolved from PerkinElmer's 25-year history in informatics, prioritizing user-friendly interfaces and validated support to integrate with hardware like spectrometers and imagers.[58][67]Notable Projects and Contracts
Hubble Space Telescope Optics Contract
In 1977, the National Aeronautics and Space Administration (NASA) awarded Perkin-Elmer Corporation the prime contract for the design and fabrication of the Hubble Space Telescope's (HST) Optical Telescope Assembly (OTA), including the primary and secondary mirrors, as well as the Fine Guidance Sensors.[68] The initial bid from Perkin-Elmer totaled $64.28 million, undercutting competitor Eastman Kodak's $99.79 million proposal, which included additional independent testing of the optics.[69] Over the course of the project, the contract value escalated due to delays and technical challenges, contributing to the HST program exceeding its budget by approximately $700 million and launching seven years late in 1990.[70] Perkin-Elmer's Danbury, Connecticut, optics division handled the grinding and polishing of the 2.4-meter primary mirror using a custom reflective null corrector for interferometric testing to achieve the required hyperbolic figure.[71] Fabrication occurred in a dedicated facility built in 1968, with the primary mirror grinding process captured in 1979.[71] However, an assembly error in the null corrector—protective caps on spacing rods were not removed, resulting in rods 1.3 millimeters too short—introduced a systematic flaw in the test measurements.[72] This led to the primary mirror being polished with a spherical aberration, deviating from the intended prescription by approximately 2 micrometers at the edge, rendering about 15% of the incoming light unusable upon HST's deployment.[73] The aberration was confirmed through post-launch diagnostics in 1990, prompting NASA to commission corrective optics via the Wide Field and Planetary Camera 2 (WFPC2) instrument, installed during Servicing Mission 1 in December 1993 at a cost exceeding $500 million.[71] Investigations, including the 1990 report by the HST Optical Systems Board of Investigation chaired by Lewis Allen, attributed the error to Perkin-Elmer's testing procedures and failure to heed independent verification discrepancies, though the company maintained the mirrors met their internal specifications.[74] In 1993, Perkin-Elmer and Hughes Aircraft Company, involved in the OTA integration, settled NASA's claims by paying $25 million collectively, with Perkin-Elmer contributing $15 million, avoiding litigation over alleged negligence in quality assurance.[75] This incident highlighted systemic issues in contractor oversight and the risks of cost-driven decisions prioritizing unproven testing methods over redundant validations.[73]KH-9 Hexagon Reconnaissance Program
The KH-9 Hexagon, also known as Big Bird, was a series of photoreconnaissance satellites launched by the United States from 1971 to 1986 to provide high-resolution mapping and intelligence imagery during the Cold War.[76] PerkinElmer Corporation, based in Danbury, Connecticut, served as the primary contractor for the satellite's advanced camera and optics systems, developing the panoramic mapping camera that enabled wide-area coverage with resolutions of 6 to 12 meters.[77] The company secured the contract in 1966 after competing against firms like Itek, leveraging its expertise in precision optics to design a system capable of exposing up to 4.5 million square feet of film per mission using six film cassettes.[78] This marked PerkinElmer's significant entry into classified national security projects, building on prior work in aerial reconnaissance optics.[79] The core innovation was the Hexagon Mapping Camera (HMC), a panoramic system with a 70-degree field of view and a focal length of approximately 152 centimeters, paired with auxiliary stellar and terrain cameras for precise attitude control and stereo imaging.[80] PerkinElmer's design addressed challenges such as maintaining optical stability in orbit, with the camera housing a complex mechanism to scan across 120 degrees laterally while compensating for spacecraft motion.[76] Film, supplied by Eastman Kodak, was returned via reentry capsules, yielding millions of images that supported strategic mapping of Soviet and Chinese military sites.[81] Engineers like Phil Pressel at PerkinElmer overcame secrecy constraints to recruit talent and iterate designs, ensuring reliability despite the program's scale—each satellite weighed about 13,500 kilograms and measured 20 meters in length.[82] Of the 20 KH-9 missions launched atop Titan IIID rockets from Vandenberg Air Force Base, 19 were successful, with the final operational flight in 1986 before transitioning to digital electro-optical systems like KH-11.[77] PerkinElmer's contributions extended to reliability assurance and integration with Lockheed's satellite bus, enabling the program to return over 700,000 feet of film and produce maps covering vast territories with unprecedented detail for the era.[83] Declassified in 2011, the program's imagery has since aided civilian applications, including geological and archaeological studies, underscoring the dual-use value of PerkinElmer's optical engineering.[76]Other Defense and Space Contributions
During World War II, Perkin-Elmer significantly expanded its operations to supply optical components for military applications, including instruments and lenses for airplane range finders, bombsights, and reconnaissance systems, which contributed to the company's profitability and growth.[1] In 1942, it became the first optical instrument manufacturer to receive the Navy "E" award for excellence in production.[1] The firm also developed panoramic reconnaissance cameras for the U.S. Department of Defense, enhancing aerial intelligence capabilities during the conflict.[17] Post-war, Perkin-Elmer continued to provide advanced optics for defense needs, designing lens systems for weapons sighting and other military applications through the 1960s and 1980s.[1] In more recent decades, its optoelectronics division secured contracts for critical components, such as in 2003 when it won over $16 million in awards for charged-coupled devices used in military and aerospace systems.[84] Additionally, Perkin-Elmer supplied firing modules and power supplies for electronic safe-and-arm fuze systems in missile defense programs under a Lockheed Martin contract extending through mid-2005.[85] In space applications, Perkin-Elmer's Optoelectronics group provided near-infrared-enhanced silicon avalanche photodiode detectors for NASA's space-based laser altimetry missions starting in 1990, supporting measurements in programs like those for topographic mapping from orbit.[86] These detectors enabled precise ranging and data collection in low-light conditions across multiple satellite platforms.[86]Acquisitions, Divestitures, and Corporate Evolution
Major Acquisitions Timeline
PerkinElmer expanded its portfolio through targeted acquisitions, particularly in life sciences, diagnostics, and analytical technologies, with several high-value deals in the 2000s and 2010s accelerating growth in drug discovery and health sciences.[1]- September 2001: Acquired Packard BioScience Company for approximately $650 million, integrating advanced bioscience detection technologies and expanding capabilities in high-throughput screening.[87]
- September 2011: Acquired Caliper Life Sciences for $600 million, adding microfluidic and lab automation tools to enhance drug discovery workflows.[31]
- December 2017: Acquired EUROIMMUN US, Inc., a provider of autoimmune and infectious disease diagnostics, for an undisclosed amount reported as a key expansion in clinical diagnostics (part of $1.6 billion in 2017 acquisitions across three deals).[88][89]
- November 2020: Acquired Horizon Discovery Group plc for $383 million, bolstering cell engineering and gene editing tools for research applications.[90]
- January 2021: Announced acquisition of Oxford Immunotec Global PLC for $591 million, completed in March 2021, to strengthen tuberculosis and lymphoma diagnostics platforms.[91][92]
- July 2021: Acquired BioLegend, Inc., for $5.25 billion (its largest deal), completed in September 2021, adding high-quality antibodies and reagents for immunology and neuroscience research.[93][94]