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Sternal fracture

A sternal fracture is a break in the sternum, the flat bone at the center of the chest that connects the rib cage and protects vital organs such as the heart and lungs, most commonly caused by blunt anterior chest wall trauma or deceleration injuries like those occurring in motor vehicle collisions. These fractures have an incidence of 3% to 6.8% among patients involved in motor vehicle accidents, with seat belt use paradoxically increasing the risk due to the force applied across the chest. Sternal fractures are more prevalent in older adults and slightly more common in women, often presenting with acute anterior that worsens with deep breathing, coughing, or movement, along with localized tenderness, swelling, or ecchymosis in approximately 50% of cases. Up to 20% of patients may also experience , and about two-thirds have associated injuries, including pulmonary contusions, rib fractures, or cardiac contusions, which elevate the risk of complications. The overall for isolated sternal fractures is low at 0.7%, but rises to approximately 8% in patients with associated injuries (as of 2024). Diagnosis typically begins with a detailed history and physical examination, followed by imaging such as chest radiographs, with anteroposterior views having about 50% sensitivity but lateral views offering improved detection, or computed tomography (CT) scans for confirmation and to assess for associated injuries; ultrasound is an emerging option with high sensitivity (up to 100%). Management follows Advanced Trauma Life Support (ATLS) protocols, prioritizing airway, breathing, and circulation stabilization; isolated, nondisplaced fractures are usually treated conservatively with analgesia, rest, and monitoring, while displaced or unstable fractures may require surgical fixation using plates or wires. Complications can include chronic pain lasting 4-12 weeks, nonunion, or rare infections like osteomyelitis, underscoring the need for thorough follow-up.

Background

Anatomy of the Sternum

The , or breastbone, is a flat, elongated bone situated in the anterior midline of the , forming the central component of the thoracic cage. It develops from multiple centers and is anatomically divided into three primary segments: the manubrium, the body, and the . The manubrium represents the superior, quadrangular portion, characterized by a broad upper border with the (jugular notch) centrally and paired clavicular notches laterally for articulation with the clavicles. The body, the longest and most robust segment, consists of four sternebrae—individual bony elements—fused by fibrocartilaginous discs, resulting in a slightly concave posterior surface and transverse ridges on the anterior aspect that correspond to the intersternebral junctions. The forms the inferior, cartilaginous or variably ossified tip, typically triangular in shape and pointing downward, serving as an attachment for abdominal structures. The sternum articulates superiorly with the clavicles at the sternoclavicular joints and with the costal cartilages of the first and second ribs via its manubrium. The body connects to the costal cartilages of the second through seventh ribs, with the articulation of the second rib defining the sternal angle (angle of Louis), a clinically significant landmark indicating the level of the second intercostal space and the bifurcation of the trachea. These costosternal junctions, reinforced by synovial or synchondrodial articulations, contribute to the flexibility and stability of the thoracic cage during respiration. Functionally, the sternum protects vital thoracic organs, including the heart, great vessels, and portions of the lungs within the mediastinum, while providing key attachment points for pectoral girdle muscles such as the pectoralis major and sternocleidomastoid, as well as the diaphragmatic slips and abdominal rectus sheath. The blood supply to the is predominantly derived from the (also known as the internal mammary artery), which arises from the and descends along the inner surface of the anterior chest wall, giving off anterior intercostal, sternal, and perforating branches that nourish the bone and overlying structures. Venous drainage parallels the arterial supply via the internal thoracic veins, ultimately emptying into the brachiocephalic veins. Innervation is supplied by branches of the (ventral rami of thoracic spinal nerves T1–T11), which provide sensory and motor input to the sternal and associated musculature, facilitating and pain signaling from the anterior . Anatomical variations in the are relatively common and arise from differences in embryonic and . The body and typically ossify from multiple centers during childhood, with the sternebrae fusing progressively by adolescence; however, incomplete may persist in adults, leading to subtle ridging or pseudofissures. Congenital anomalies include sternal clefts, resulting from failure of the bilateral sternal primordia to fuse in the midline during the sixth to ninth weeks of , with an estimated incidence of 1 in 50,000 to 100,000 live births; these may be complete (bifid sternum) or partial. Another frequent variation is the sternal , a central defect in the body due to incomplete or resorption, occurring in 2.5% to 13.8% of the population and more commonly in males. The exhibits significant variability in shape (e.g., elongated, bifid, or curved) and timing, often remaining partially cartilaginous into adulthood or calcifying irregularly by age 40 to 60.

Epidemiology

Sternal fractures occur in approximately 3% to 8% of patients with blunt chest , with rates reaching up to 18% in cases of involving thoracic injuries. In collisions, the incidence is reported between 3% and 6.8%, reflecting the high-impact deceleration forces common in such events. Overall, sternal fractures represent about 0.33% of all admissions, underscoring their relative rarity in broader populations. Demographically, sternal fractures are more prevalent in males, with a male-to-female ratio of approximately 2:1, as evidenced by studies showing 63% to 76% of cases occurring in men. While overall more common in males (2:1 ratio) in cohorts, sternal fractures in the elderly (>65 years) from low-energy mechanisms like falls are more frequent in females due to . The typical age at presentation peaks between 30 and 50 years, with mean ages around 41 to 44 years reported in large cohorts. Incidence is rising among the elderly, particularly those over 65, due to age-related bone fragility from , which increases susceptibility to fractures from lower-energy impacts. As of 2019, global incident cases of sternal and/or rib fractures reached 4.1 million, with incidence rising and the gender gap narrowing per projections to 2030. Mortality associated with isolated sternal fractures is low at 3.5%, based on analyses from the National Trauma Data Bank (NTDB). However, overall mortality rises significantly to 8.8% when sternal fractures occur alongside other injuries, such as pulmonary contusions or thoracic vascular damage, with outcomes heavily influenced by the severity and number of concomitant traumas. Data from the NTDB highlight that isolated cases carry minimal risk, while contexts elevate fatality rates substantially. The incidence of sternal fractures has increased since the , coinciding with the widespread adoption of seatbelt legislation and rising traffic volumes, which promote anterior chest wall loading during deceleration. This trend is attributed to the protective yet forceful restraint provided by three-point seatbelts, leading to a higher detection of isolated sternal injuries in restrained occupants compared to pre-legislation eras.

Pathophysiology

Causes

Sternal fractures most commonly result from to the anterior chest wall, accounting for the majority of cases. accidents represent the primary traumatic etiology, comprising approximately 68% of sternal fractures, typically from direct impact against the steering wheel during deceleration. Other frequent mechanisms include falls from height (7.9% of cases) and collisions (7.9%), while and assaults contribute less commonly through similar direct force application. Iatrogenic causes arise during medical interventions involving chest compression. (CPR) is a notable factor, with sternal fractures reported in 1% to 43% of prolonged efforts, depending on duration and technique. Direct chest compressions in other procedures, such as during cardiac interventions, can similarly induce fractures due to repeated anterior force. Pathologic sternal fractures occur secondary to underlying bone-weakening conditions rather than acute trauma. , particularly in postmenopausal women or those on long-term steroids, leads to insufficiency fractures exacerbated by thoracic . Malignancies, such as breast or , cause pathologic fractures via sternal , observed in up to 15% of advanced cancer cases at . Metabolic bone diseases, including , further predispose to such fragility. Rare etiologies include blast injuries from explosions, which transmit high-pressure waves or fragments to the chest, and direct impacts from animal attacks, both representing exceptional variants.

Mechanisms of Injury

Sternal fractures commonly result from anterior-posterior compression forces applied directly to the anterior chest wall, such as during from a impact in collisions. These forces cause the to bear the brunt of the load, typically leading to transverse fractures of the sternal body due to the bone's limited ability to dissipate energy in this direction. Flexion and shear forces, often arising from rapid deceleration in high-energy impacts like car crashes, can also induce fractures, particularly at the manubrium or sternal body. In these scenarios, the sudden forward momentum of the relative to the fixed creates bending moments and sliding stresses across the , disrupting its continuity and potentially causing oblique or displaced breaks. Pathophysiologic weakening of the , such as in , significantly lowers the force required for by reducing bone mineral density and trabecular integrity. A T-score below -2.5 indicates , which compromises the bone's and increases susceptibility to insufficiency fractures even under minimal trauma, as seen in cases with T-scores as low as -3.21. The sternum's relative immobility, anchored firmly to the and clavicles while the allows some flexibility during and movement, results in amplified localized during traumatic loading. This concentrates forces on thinner cortical regions, such as the mid-body, exacerbating risk compared to the more compliant surrounding thoracic .

Clinical Presentation

Signs and Symptoms

Patients with sternal fractures typically present with moderate to severe anterior localized to the , which is often exacerbated by deep breathing, coughing, sneezing, or movement. This pain is usually acute and exquisite, with point tenderness elicited upon palpation of the . Physical examination may reveal localized swelling, ecchymosis (sometimes manifesting as a "seat belt sign"), and bony crepitus or a clicking sensation during respiration or palpation. In approximately half of cases, soft tissue swelling or ecchymoses are visible, and severe fractures may show palpable deformity, though paradoxical motion is rare in isolated injuries. Systemic symptoms are less common in isolated sternal fractures but can include dyspnea in up to one-fifth of patients, potentially due to pleural involvement or pain-related ; however, severe respiratory distress is uncommon without associated injuries. Symptom severity generally ranges from mild, characterized primarily by localized , to more severe presentations involving significant dyspnea or discomfort impacting mobility, though hemodynamic instability typically indicates concurrent trauma rather than the fracture alone. Brief for potential associated organ damage, such as cardiac or , is essential if symptoms extend beyond local findings.

Associated Injuries

Sternal fractures often occur in the context of high-impact blunt chest , such as collisions, and are frequently accompanied by multisystem injuries that significantly influence clinical outcomes. Up to two-thirds of cases involve associated injuries, which can involve the cardiovascular, pulmonary, and musculoskeletal systems, arising from the same deceleration or direct impact forces. Cardiac injuries are a notable concern, with myocardial contusion occurring in 6% to 18% of patients, depending on trauma severity; these may manifest as arrhythmias or wall motion abnormalities detected via electrocardiogram (ECG) changes, such as ST-segment elevation, and elevated levels. or, less commonly, cardiac rupture can also arise, potentially leading to and requiring prompt evaluation with . Blunt cardiac injury overall affects approximately 3.6% of cases in large databases. Pulmonary injuries are among the most prevalent associations, occurring in up to 50% of patients with sternal fractures. is the leading such injury at 33.7%, often contributing to respiratory compromise, while (22%) and are also frequent, stemming from direct thoracic compression or shearing forces. Vascular injuries, including , are less common but critical, with an incidence of less than 2% in sternal fracture cases, typically resulting from rapid deceleration that stretches the . Spinal injuries, particularly vertebral fractures, are associated in about 21.6% of instances, often involving the thoracic (T1-T6) due to flexion-distraction mechanisms; these may be overlooked without targeted imaging. The presence of associated injuries markedly elevates risk, with mortality rates reaching 25% to 45% in such cases, compared to near-zero (0.7%) for isolated sternal fractures, underscoring the need for comprehensive .

Diagnosis

Clinical Evaluation

Clinical evaluation of a suspected sternal fracture begins with a detailed to identify the mechanism of injury, which most commonly involves blunt anterior chest wall from collisions (accounting for approximately 68% of cases) or falls (about 7.9%), often in the context of high-impact deceleration forces. Patients typically report localized anterior chest wall pain that intensifies with deep breathing, coughing, or movement, and associated symptoms may include in up to 20% of cases, with rarer presentations such as suggesting potential concurrent injuries such as or vascular disruption. Targeted questioning focuses on the timing and nature of the pain to differentiate from non-traumatic causes. The involves systematic , , and to assess for injury severity and complications. may reveal soft-tissue swelling, ecchymosis, or in around 50% of patients, while elicits point tenderness or at the site, though displacement is uncommon unless the injury is severe. evaluates breath sounds for asymmetry indicative of associated thoracic injuries like , and are monitored closely for signs of hemodynamic instability or , such as or , particularly in cases with comorbidities. Differential diagnosis requires distinguishing sternal fracture from conditions like (characterized by reproducible pain without trauma history), (prompted by radiation to the arm or jaw and ECG changes), or (suggested by sudden dyspnea without chest wall tenderness) through focused history and exam elements, such as the absence of systemic symptoms or normal cardiac biomarkers. Trauma scoring tools, including the (GCS) for neurological assessment and the (RTS) incorporating and GCS, are employed to stratify injury severity and prioritize care in patients with suspected sternal fractures. If clinical suspicion remains high, confirmatory imaging such as chest radiography may follow.

Diagnostic Imaging

Plain radiography serves as the initial imaging modality for suspected sternal fractures, typically involving posteroanterior () and lateral chest X-rays. The view has a of approximately 50% for detecting sternal fractures, while the lateral view improves diagnostic accuracy by visualizing transverse fractures and any in the . However, plain radiographs are prone to false negatives, particularly in obese patients or those with non-displaced fractures, where overlying soft tissues or subtle disruptions may obscure findings. Computed tomography (CT) scanning is considered the gold standard for confirming and characterizing sternal fractures, offering superior and detailed visualization compared to plain radiography. Spiral or multi-slice is particularly effective, detecting up to 94% of fractures that may be missed on X-rays, and allows for to assess displacement, fragment alignment, and associated thoracic injuries such as aortic or cardiac . In trauma protocols, chest is routinely performed in patients with high clinical suspicion, identifying concomitant injuries in over 80% of cases. Additional imaging modalities include for bedside evaluation, especially in unstable patients, and (MRI) for assessing involvement. Clinician-performed demonstrates equal to or greater than plain radiography (around 88.5% in cases), rapidly identifying cortical disruptions or step-offs without , though it is operator-dependent and less effective for assessment. MRI is reserved for equivocal cases involving myocardial contusion or ligamentous , providing excellent contrast but limited by availability and patient tolerability in acute settings. Key limitations of these modalities include radiation exposure risks from plain radiography and , which must be balanced against diagnostic benefits in younger patients, and challenges in detecting non-displaced or minimally displaced fractures across all techniques. Axial views may occasionally miss transverse fractures, underscoring the need for multiplanar reconstructions.

Treatment

Initial Management

The initial management of sternal fractures follows the (ATLS) guidelines, emphasizing the ABCDE approach to prioritize life-threatening conditions. Airway patency is secured first, with cervical spine immobilization if indicated, followed by assessment of breathing to identify and treat issues such as tension pneumothorax or through supplemental oxygen administration if is present. Circulation is stabilized by establishing intravenous access and administering fluids as needed to maintain hemodynamic stability, alongside rapid evaluation for associated cardiac injuries. Pain control is a cornerstone of for isolated sternal fractures, typically achieved with analgesics such as nonsteroidal drugs (NSAIDs) or opioids, titrated to avoid respiratory depression that could exacerbate pulmonary complications. Multimodal analgesia, including acetaminophen and regional blocks if severe, supports adequate relief to facilitate deep breathing and mobility. Patients undergo continuous monitoring, including serial cardiac enzyme measurements (e.g., or T) and (ECG) to detect myocardial contusion, arrhythmias, or ST-segment changes, with a second level checked 4-6 hours after the initial normal result if suspicion persists. In low-risk cases without associated injuries or instability, observation for 24-48 hours in a monitored setting suffices, allowing discharge with outpatient follow-up. Immobilization focuses on comfort rather than rigid fixation, often using a , soft , or sternal bracing to reduce and stabilize the site during initial recovery. Early mobilization, supported by and respiratory exercises, is encouraged within 24-48 hours to prevent , , and , particularly in elderly patients. Sternal bracing has been shown to enable pain-free ambulation, simplify , and shorten stays to an average of 4 days in select cases.

Surgical Interventions

Surgical interventions for sternal fractures are reserved for cases where fails or specific complications arise, such as leading to respiratory compromise, significant displacement with offset greater than 50%, or associated intrathoracic injuries necessitating . These indications ensure that surgery addresses instability, persistent severe pain, or threats to cardiac or pulmonary function, while most isolated fractures (>95%) heal without operative intervention. The primary technique involves open reduction and (ORIF), which stabilizes the fracture through direct exposure via . Fixation methods include wires for simple approximation, particularly in comminuted fractures, and titanium plates secured with locking screws for rigid stabilization in displaced or unstable cases. Minimally invasive approaches, such as endoscopic-assisted wiring, have been described to reduce incision size and tissue trauma, though they are less commonly applied than open methods. Postoperative care emphasizes infection prevention with prophylactic antibiotics administered perioperatively, typically continued for 24-48 hours or until chest tubes are removed if present. Chest tubes are placed intraoperatively if there is risk of or , with routine postoperative imaging to confirm positioning and exclude complications. Surgical outcomes demonstrate high efficacy, with sternal healing achieved in 98% of cases and significant pain relief reported in the majority of patients, outperforming in reducing and opioid requirements. These results highlight improved respiratory function and , particularly in unstable fractures, with low complication rates around 2%.

Prognosis and Prevention

Complications and Outcomes

Sternal fractures, particularly isolated ones, carry a low risk of acute complications, but associated injuries can elevate morbidity. Painful breathing often leads to shallow respirations, increasing the risk of and , with reported incidence rates around 10-12% in conservatively managed cases. Delayed union or non-union occurs rarely, affecting less than 1% of patients, though it may necessitate surgical if symptomatic. Other acute issues include potential cardiac contusions or pericardial effusions, though these are more common in high-impact . Long-term outcomes for isolated sternal fractures are generally favorable, with most patients achieving full within 4-6 weeks, though may persist for 8-12 weeks in some. affects a notable portion, with approximately % of patients experiencing moderate to severe at 90 days post-injury, often related to persistent and exacerbated by movement or . Impaired respiratory function can linger due to ongoing discomfort, and cosmetic deformities such as sternal overlap may occur in untreated displaced fractures, impacting . Non-union, when it develops, contributes to persistent instability and discomfort, but surgical fixation yields high healing rates (over 98%) and relief in affected individuals. Prognostic factors include advanced age (over 50 years), which prolongs symptom duration; comorbidities such as or , which delay healing; and higher injury severity scores (ISS >16), which correlate with worse overall outcomes due to associated thoracic . Patients with face elevated risks compared to those with isolated fractures. Mortality from isolated sternal fractures remains low at under 1%, primarily driven by associated injuries like or severe rather than the fracture itself. In hospitalized patients, 30-day mortality reaches about 8%, rising to 25-45% with significant concomitant injuries.

Prevention

Preventing sternal fractures primarily involves targeted measures to mitigate high-impact to the chest, such as those from accidents, falls, and certain medical procedures. In vehicular contexts, proper use of three-point seatbelts is essential, as they distribute crash forces across the body and reduce the of fatal injuries by approximately 45%, though belted occupants may still experience sternal fractures in severe collisions due to direct compression against the restraint. Airbags complement seatbelts by providing additional cushioning during frontal impacts, further lowering mortality from thoracic when deployed correctly, with combined use reducing overall by 61% in frontal crashes. Advances in design, including energy-absorbing materials and collapsible columns, minimize chest intrusion during crashes, thereby decreasing the incidence of sternal impacts compared to older vehicles. Fall prevention strategies are particularly important for older adults, who are at higher risk of low-energy falls leading to sternal fractures due to reduced and balance. Home modifications, such as installing grab bars near toilets and in bathtubs, removing loose rugs, and ensuring adequate lighting, have been shown to significantly lower fall rates by improving and . In sports activities, wearing appropriate protective gear like helmets can indirectly reduce the risk of falls or collisions that might result in chest , although helmets primarily safeguard the head; for contact sports, additional chest protectors are recommended to absorb impacts. Comprehensive programs incorporating exercise, environmental assessments, and assistive devices further decrease injury incidence among at-risk populations. During (CPR), employing proper techniques helps balance effective circulation with minimizing skeletal injuries like sternal fractures, which occur in about 20% of attempts due to the force required. Rescuers should aim for chest compression depths of 5-6 cm at a rate of 100-120 per minute, using straight-arm positioning and body weight distribution to avoid excessive force, as depths exceeding 6 cm increase fracture risk. Training emphasizes perpendicular compression on the lower and full chest recoil between cycles to optimize outcomes while reducing . Public health initiatives targeting play a key role in preventing sternal , which arise from weakened structure rather than high . The U.S. Preventive Services Task Force recommends screening postmenopausal women aged 65 and older—or younger women at increased risk—using to identify low early, enabling interventions like calcium supplementation, exercise, and medications that reduce risk by up to 20-30% for major sites. health programs, including assessment and lifestyle counseling, further mitigate in the and other areas by addressing underlying . As of 2025, global burden analyses project increasing trends in sternal and rib due to aging populations, underscoring the need for enhanced prevention strategies.

Historical Perspectives

Early Recognition

The earliest documented references to chest trauma in medical literature date back to ancient times, with Hippocratic texts from around 400 BCE describing blunt injuries to the chest wall, such as rib fractures leading to and respiratory complications, though these accounts lack a specific focus on the itself. Such descriptions emphasized the vulnerability of the thoracic cage to direct blows but treated sternal involvement as part of broader contusions rather than isolated pathology. A significant advancement in understanding the sternum's —and by extension, its susceptibility to —occurred in the through the work of . In his seminal 1543 publication De humani corporis fabrica, Vesalius detailed the sternum's composition as three distinct segments (manubrium, body, and ) based on direct human dissections, correcting Galen's erroneous claim of seven parts derived from animal studies and underscoring the bone's relatively thin, subcutaneous position that predisposes it to traumatic disruption. This anatomical precision laid foundational knowledge for later recognition of sternal injuries, though Vesalius himself did not report clinical fractures. Sternal fractures emerged as a recognized entity in the during the , coinciding with the Revolution's rise in high-impact accidents involving machinery, falls, and early rail collisions. examinations of these victims frequently revealed sternal disruptions alongside other thoracic injuries, marking the first systematic documentation of the condition as a complication of blunt force. These postmortem studies highlighted the fracture's association with severe deceleration or direct anterior chest impacts, often fatal due to concomitant cardiac or pulmonary damage. Before the , sternal fractures remained exceedingly rare, primarily because trauma mechanisms were limited to low-velocity incidents like falls from modest heights or manual labor mishaps, which seldom generated the force required to break the sternum's resilient structure. This scarcity contributed to delayed clinical awareness, with most cases only identified incidentally during autopsies rather than in living patients.

Evolution in Diagnosis and Treatment

The rise of automobile use in the early , particularly during the , marked a significant milestone in the of sternal fractures, as collisions became a leading cause of blunt chest trauma and increased the reported incidence of these injuries. The discovery of X-rays by in 1895 enabled the first radiographic visualization of fractures, and by the 1930s, lateral chest radiographs had become a standard diagnostic tool for confirming sternal fractures, improving detection rates over clinical examination alone. Following , the introduction and mandatory use of seatbelts in the 1960s highlighted a new pattern of sternal fractures, often resulting from deceleration forces transmitted across the chest, as documented in early studies of restrained occupants. By the , clinical experience led to a toward for the majority of isolated sternal fractures, emphasizing analgesia, respiratory support, and observation, given the low rate of complications in stable cases. The first surgical fixation of a sternal fracture was reported in 1943 using Kirschner wires, with further developments in intramedullary fixation using Rush pins in 1957 and Steinmann pins in 1972. Advancements from the 1980s onward further refined diagnosis and treatment. The development of computed tomography (CT) in the 1970s provided superior visualization of sternal fractures and associated injuries, such as retrosternal hematomas, leading to a notable increase in detection rates. Surgical fixation techniques for unstable or displaced fractures advanced in the late with open reduction and (ORIF), including plating systems, offering better stabilization and reducing compared to earlier nonoperative approaches. Contemporary guidelines, including those from (ATLS, 11th edition, 2025), integrate these modalities into a systematic evaluation protocol, prioritizing multidisciplinary assessment for patients. Looking to future directions, bioabsorbable fixation devices, such as poly-L-lactide plates, show promise for reducing long-term complications like hardware removal and infection in selected cases. Additionally, artificial intelligence-assisted imaging is emerging to enhance diagnostic accuracy in detecting subtle sternal fractures on radiographs and scans, potentially streamlining workflows.

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