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Triethanolamine

Triethanolamine, also known as trolamine or 2,2',2''-nitrilotriethanol, is a tertiary amine and triol with the molecular formula C₆H₁₅NO₃ and IUPAC name 2-[bis(2-hydroxyethyl)amino]ethanol.^[1] It appears as a colorless to pale yellow viscous liquid with a mild ammonia-like odor, is miscible in water, and has a boiling point of 335.4°C and a freezing point of 21.6°C.^[1] This compound serves as a versatile industrial chemical, primarily used as an emulsifier, surfactant, and pH adjuster in cosmetics and personal care products, where it helps stabilize formulations and is deemed safe as used when formulated to be non-irritating.^[2] In pharmaceuticals, it functions as an alkalizing agent and buffering agent, while in broader industrial applications, it is employed in textile processing, cement additives, herbicides, lubricants, and as an intermediate in the production of resins and plasticizers.^[1] Annual production volume in the European Economic Area exceeds 100,000 tonnes, reflecting its widespread use across consumer, professional, and industrial sectors.^[3] Triethanolamine exhibits low acute toxicity, with an oral LD₅₀ in rats ranging from 4,190 to 11,260 mg/kg, but it is classified as a skin and eye irritant and suspected of damaging fertility based on regulatory assessments.^[1]^[3] It is not classified as carcinogenic by the International Agency for Research on Cancer (Group 3), though exposure limits such as a threshold limit value of 5 mg/m³ (8-hour time-weighted average) are recommended to mitigate respiratory and dermal risks.^[1] Environmentally, it shows moderate persistence in water but low bioaccumulation potential, with ecotoxicity data indicating an LC₅₀ of 11.8 g/L for fathead minnows over 96 hours.^[1]

Structure and properties

Molecular structure

Triethanolamine, with the chemical formula \ce{C6H15NO3}, is commonly represented as \ce{N(CH2CH2OH)3} or \ce{(HOCH2CH2)3N}.^[1] It is a tertiary amine derived from ammonia, where the central nitrogen atom is bonded to three 2-hydroxyethyl groups (\ce{-CH2CH2OH}), forming a structure with a single nitrogen atom connected via three C-N single bonds to the carbon chains, each terminating in a hydroxyl group.^[1] This molecular arrangement can be visualized as a central N atom with three symmetric arms, each consisting of an ethylene bridge (\ce{-CH2-CH2-}) linked to an \ce{-OH} moiety.^[1] In comparison to related ethanolamines, triethanolamine features full substitution on the nitrogen with three hydroxyethyl groups, whereas monoethanolamine (MEA, \ce{H2NCH2CH2OH}) has one such group and a primary amine, and diethanolamine (DEA, \ce{HN(CH2CH2OH)2}) has two with a secondary amine.^[1]^[4]^[5] The tertiary amine functionality imparts basic properties by allowing the nitrogen to accept a proton, while the three hydroxyl groups contribute hydrophilic characteristics, enhancing interactions with water through hydrogen bonding.^[6]

Physical properties

Triethanolamine is a colorless to pale yellow viscous liquid at room temperature, exhibiting a mild ammoniacal odor.^[1] It solidifies below its melting point of 21.6 °C, forming hygroscopic crystals, while boiling occurs at 335.4 °C under standard pressure.^[1] The compound has a density of 1.124 g/mL at 20 °C and a dynamic viscosity of approximately 590 cP at 25 °C, contributing to its oily texture.^[1] Its refractive index is 1.485 at 20 °C.^[1] Triethanolamine is highly hygroscopic, readily absorbing moisture from the atmosphere, and remains stable under ambient conditions but may turn brown upon prolonged exposure to air and light.^[1] It is miscible with water, ethanol, and acetone, enhancing its utility in aqueous and polar solvent systems, though solubility in non-polar solvents like benzene is limited to about 4.2 g/100 mL.^[1]

Property	Value	Conditions
Density	1.124 g/mL	20 °C
Melting point	21.6 °C	-
Boiling point	335.4 °C	760 mmHg
Dynamic viscosity	590 cP	25 °C
Refractive index	1.485	20 °C

^[1]

Chemical properties

Triethanolamine functions as a strong base owing to its tertiary amine group, with the pKa of its conjugate acid reported as 7.76 at 25°C.^[1] This moderate basicity arises from the availability of the lone pair on the nitrogen atom for protonation. In aqueous solutions, a 1% solution exhibits a pH of approximately 10, reflecting its ability to generate hydroxide ions.^[1] In water, triethanolamine undergoes partial dissociation, establishing an acid-base equilibrium where it accepts a proton from water to form the triethanolammonium cation and hydroxide anion:

\text{N(CH}_2\text{CH}_2\text{OH)}_3 + \text{H}_2\text{O} \rightleftharpoons [\text{N(CH}_2\text{CH}_2\text{OH)}_3\text{H}]^+ + \text{OH}^-

This equilibrium is governed by the pKa value, resulting in a mixture of the neutral base and its protonated form depending on the solution pH.^[1]^[7] The basic nature enables triethanolamine to form salts with various acids through protonation of the nitrogen atom. For example, it reacts with hydrochloric acid to produce triethanolamine hydrochloride, a water-soluble salt used in certain formulations.^[8] Similar salts form with other acids, such as nitric acid yielding triethanolamine nitrate.^[9] Triethanolamine exhibits chelating properties toward metal ions, including aluminum, due to its dual amine-alcohol functionality. The nitrogen lone pair and oxygen atoms from the hydroxy groups act as electron donors, forming coordinate bonds with the metal center to create stable chelate complexes; this multidentate coordination enhances binding affinity compared to monodentate ligands.^[10]^[11] Triethanolamine possesses reasonable thermal stability under normal conditions but decomposes when heated to elevated temperatures, typically above 200°C, via pathways involving cleavage of C-N and C-O bonds. Decomposition products include toxic nitrogen oxides (NOx) and hydrogen cyanide (HCN), along with volatile organics from fragmentation of the ethanolamine moieties.^[1]^[12] Regarding oxidation, triethanolamine demonstrates limited resistance, as it reacts vigorously with strong oxidizing agents, potentially leading to oxidative degradation of the amine or alcohol groups. Its reactivity with electrophiles stems from the nucleophilic character of the nitrogen and oxygen sites; the tertiary nitrogen can attack electrophiles like alkyl halides to form quaternary ammonium salts, while the hydroxyl oxygens participate in reactions such as esterification with acid chlorides.^[1]^[13]

Production

Industrial synthesis

Triethanolamine is produced industrially by reacting ethylene oxide with excess aqueous ammonia under controlled conditions, which simultaneously produces monoethanolamine and diethanolamine. The reaction is typically accelerated by water or using an anhydrous fixed-bed ion-exchange resin catalyst.^[14] Pure, colorless product has been economically feasible since the mid-1970s.^[14]

Commercial aspects and history

Triethanolamine (TEA) was first produced commercially in 1928, marking the initial large-scale synthesis through the reaction of ethylene oxide with ammonia, a process that evolved from early 20th-century experiments with alcohol-amine hybrids.^[15] This development followed foundational patents, such as one granted in 1930 to R.R. Bottoms for using TEA in gas sweetening applications, which highlighted its potential as an industrial intermediate.^[16] By the early 1930s, ethanolamines including TEA became commercially available, with production scaling up significantly after 1945 due to increased ethylene oxide availability and post-war industrial demand.^[14] Global production of TEA reached approximately 150,000 tonnes in 1999, reflecting its growing role in chemical manufacturing.^[17] By 2024, output had expanded to around 518,000 tonnes annually, driven by steady demand in key sectors and an estimated compound annual growth rate (CAGR) of 2.78% through 2035.^[18] Major producers include Dow Chemical Company, BASF SE, INEOS Group, Indorama Ventures, and Nouryon, which collectively dominate supply through integrated petrochemical operations.^[19] These companies have benefited from patents evolving since the 1930s, particularly those refining the ethylene oxide-ammonia process for higher yields and purity, enabling efficient scale-up.^[16] Market growth for TEA is closely tied to expanding applications in personal care products, detergents, and construction materials, where it serves as an emulsifier, surfactant, and additive.^[19] The Asia-Pacific region leads consumption, accounting for over 44% of global demand in 2024, fueled by rapid urbanization and rising hygiene standards.^[19] Bulk prices typically range from $1,000 to $1,500 per tonne, with fluctuations influenced by feedstock costs and regional supply dynamics; for instance, U.S. prices averaged $1,250 per metric ton in early 2025.^[20] Trade patterns show the United States as the leading exporter at about 65,000 tonnes annually from 2016–2023, followed by Saudi Arabia and Germany, while major importers include China and the European Union.^[21]

Applications

In personal care and cosmetics

Triethanolamine serves as a key ingredient in personal care and cosmetics formulations, primarily functioning as an emulsifier, surfactant, and pH adjuster to enhance product stability and efficacy.^[22]^[23] In sunscreens, lotions, shampoos, and hand sanitizers, triethanolamine acts as an emulsifier and surfactant at concentrations of 1-5%, enabling the blending of oil and water phases for smooth, homogeneous textures.^[24]^[25] It also stabilizes foam in cleansing products like shampoos and facial washes, improving lathering and cleaning performance.^[26]^[27] As a pH balancer, triethanolamine neutralizes acidic components in creams and shaving products, adjusting the formulation pH to a neutral to slightly alkaline range of 7-9 to ensure compatibility with skin and optimal ingredient activity.^[23] In medical applications, triethanolamine was an active component in eardrops such as Cerumenex (discontinued in 2010), where a 10% triethanolamine polypeptide oleate-condensate formulation softened and removed cerumen through emulsification of earwax.^[28] This surfactant action dispersed impacted wax for easier irrigation.^[29] Specific examples include its use in laundry detergents, dishwashing liquids, and polishes as a foam stabilizer, where it enhances sudsing and maintains product consistency in household personal care contexts.^[30] The emulsification mechanism relies on triethanolamine's three hydroxyl groups, which provide hydrophilic properties, allowing it to interact with oils in water-based systems and form stable emulsions.^[31] Its water miscibility further supports these aqueous formulations.^[1] Safety guidelines from the Cosmetic Ingredient Review limit triethanolamine to less than 5% in leave-on products to minimize potential irritation while preserving functionality.^[23]^[32]

In industrial and manufacturing processes

Triethanolamine serves as a versatile additive in various industrial and manufacturing processes, particularly where pH control, emulsification, and corrosion protection are essential. Its amphoteric nature allows it to function as a buffering agent, maintaining optimal pH levels in chemical reactions and formulations to prevent degradation or instability during production.^[33] In chemical manufacturing, it is employed to neutralize acidic components and stabilize process streams, ensuring consistent reaction conditions without introducing excessive volatility.^[34] As a corrosion inhibitor, triethanolamine is incorporated into metalworking fluids and cutting oils at concentrations of 1-3% to form protective films on metal surfaces, thereby preventing rust and extending tool life during machining operations.^[35] This application leverages its ability to chelate metal ions briefly, enhancing the fluid's alkalinity and reducing oxidative damage to ferrous and non-ferrous metals. In the formulation of water-based paints and printing inks, triethanolamine acts as an additive to stabilize emulsions by neutralizing resins and surfactants, while also adjusting viscosity to achieve desired flow properties for even application and drying.^[34] Typical usage levels range from 0.5-2% to ensure pigment dispersion and prevent settling, contributing to uniform coating performance in industrial printing processes.^[37] Triethanolamine functions as a surfactant in industrial cleaners, polishes, and degreasers designed for metal surfaces, where it reduces surface tension to facilitate the removal of oils, greases, and residues without damaging substrates.^[38] In these formulations, it enhances wetting and emulsification, allowing effective cleaning in heavy-duty applications such as automotive and machinery maintenance. In polymer processing, triethanolamine serves as a curing agent for epoxy resins and rubber compounds, promoting cross-linking reactions that improve mechanical strength and durability. For epoxy systems, dosages of 12-15 parts per hundred resin (phr) are common, with curing at 80°C for 4 hours or 120°C for 2 hours to achieve optimal network formation.^[39] In rubber vulcanization, it accelerates cross-linking, particularly in halogenated diene rubbers, when combined with metal catalysts like iron acetylacetonate.^[40] It is also used in herbicide formulations as an emulsifier and to form water-soluble salts of active ingredients like glyphosate.^[41] Common derivatives, such as triethanolamine stearate, are utilized as emulsifiers in textile processing to blend oils and water-based finishes, aiding in uniform application and reducing friction during weaving and dyeing.^[42] This derivative enhances fabric lubricity and stability in industrial-scale operations.^[23]

In construction and materials

Triethanolamine (TEA) serves as an additive in cement production at concentrations around 0.1 wt% of the cement, functioning as a grinding aid to reduce energy requirements during milling and enhance the flowability of cement particles by promoting their dispersion.^[43] This application helps prevent particle agglomeration, allowing for finer grinding and improved powder handling properties.^[44] The mechanism of TEA in cement involves surface adsorption onto cement grains, which lowers surface energy, neutralizes electrostatic charges, and inhibits re-agglomeration, thereby acting as both a grinding aid and an early-strength enhancer by facilitating better hydration kinetics.^[43] Performance studies indicate that TEA incorporation can improve grindability compared to untreated cement.^[45] TEA has been widely adopted in the cement industry since the 1930s, coinciding with the broader introduction of chemical grinding aids to optimize production efficiency.^[46] In aluminum soldering, TEA is incorporated at 1-5% in liquid organic fluxes to dissolve oxide layers on metal surfaces, thereby improving solder wetting and joint integrity during low-temperature bonding processes.^[47] This role leverages TEA's ability to act as a mild base and complexing agent, facilitating cleaner flux residues and reliable metallurgical connections.^[14] Beyond cement and soldering, TEA finds use in concrete admixtures for pH control, where it adjusts alkalinity to optimize admixture compatibility and hydration rates without significantly altering setting times.^[38] In gypsum board production, TEA is added to aqueous slurries as a surfactant to enhance foam stability and control setting, contributing to uniform board density and reduced defects during manufacturing.^[48]

In scientific and technical uses

Triethanolamine serves as a complexing agent in laboratory applications, particularly in complexometric titrations for quantifying aluminum ions. In these procedures, it acts as a selective demasking agent to release aluminum from its EDTA complex, enabling accurate back-titration. For instance, after initial masking of other metals and titration of excess EDTA, 20 mL of 30% (v/v) triethanolamine is added along with 5 mL of 10% (w/v) hydroxylamine hydrochloride to the solution, which is then boiled for 1 minute to demask the aluminum-EDTA complex. The liberated EDTA is subsequently titrated with 0.01 M Mn(II) sulfate using Erichrome Black T as the indicator, with the color changing from blue to red at the endpoint; the volume of manganese solution consumed corresponds directly to the aluminum concentration, yielding results with a standard deviation below 1.5% in validated analyses of standard reference materials.^[49] Additionally, triethanolamine functions as a pH buffer in analytical chemistry, often combined with citric acid to maintain conditions below pH 7.5 and prevent interference from complex-forming metal ions such as calcium or transition metals during determinations like fluoride in orthophosphates using ion-selective electrodes. This buffering approach ensures stable ionic environments for precise measurements without altering the target analyte's reactivity.^[50] In photography, triethanolamine is incorporated as a component in developers for amateur black-and-white processing, where it enhances sensitivity and stabilizes silver halide emulsions. Added at approximately 0.5% of the emulsion weight during preparation or as a 0.2-0.5% aqueous bath for 2 minutes at 45°F prior to drying, it hypersensitizes the emulsion layers without shifting the spectral response, improving overall pliability and image quality in traditional film development.^[51] Triethanolamine plays a key role in holography by pre-swelling silver-halide plates to boost sensitivity and control emulsion thickness. A 10% (v/v) aqueous solution is typically used to immerse plates for 1 minute, causing temporary gelatin expansion that increases refractive index modulation during exposure; upon drying post-processing, the emulsion contracts, yielding higher diffraction efficiency and color-selective reflection holograms suitable for sensing applications. This technique, investigated for swelling control in gelatin films, enhances holographic properties in both monochromatic and multi-color recordings by optimizing layer thickness for laser wavelengths.^[52]^[53] In electroless plating, triethanolamine chelates metals like nickel, promoting uniform deposition on substrates for electronics manufacturing. As a complexing agent in plating baths, it stabilizes nickel ions to prevent premature precipitation, achieving deposition rates that decrease outside 25-50 mL/L concentrations while improving mechanical properties such as hardness in the resulting nickel layers. This application ensures consistent coatings on circuit boards and components, leveraging triethanolamine's ability to maintain bath stability during autocatalytic reduction.^[54]^[55]

Safety and regulation

Health effects

Triethanolamine (TEA) can cause acute irritation upon exposure, particularly through dermal, ocular, and inhalation routes. At concentrations above 5%, it may induce mild to moderate skin irritation, with more severe effects observed at levels exceeding 10% in human patch tests and animal models. Eye contact leads to irritation and potential corneal damage, while inhalation of vapors or aerosols at occupational levels can result in respiratory tract irritation, including coughing and shortness of breath.^[14]^[23]^[56] Allergic reactions to TEA are uncommon, with a low sensitization rate reported in patch testing of cosmetic users, typically below 1% for true allergic contact dermatitis, though irritant responses may mimic allergy in some cases. Contact dermatitis is more frequently associated with prolonged exposure in cosmetics, where TEA acts as an emulsifier.^[57]^[58]^[59] Chronic exposure to TEA, especially via oral ingestion, has been linked to potential liver toxicity in animal studies, with increased liver weights and histopathological changes observed at high doses. Additionally, TEA can react with nitrosating agents in formulations to form nitrosamines, such as N-nitrosodiethanolamine, which pose a carcinogenic risk upon chronic exposure.^[14]^[60]^[61] Regarding carcinogenicity, dermal studies by the National Toxicology Program (NTP) in 1999 demonstrated clear evidence of carcinogenic activity in female B6C3F1 mice, with dose-related increases in hepatocellular adenomas (up to 33/50 at 1,000 mg/kg) and adenomas or carcinomas (up to 34/50), attributed to a choline deficiency mechanism that promotes liver tumor formation. In male mice, evidence was equivocal, based on marginal increases in hemangiosarcomas. Rat studies showed no clear carcinogenic activity, with only equivocal evidence from renal tubule adenomas in males. The International Agency for Research on Cancer (IARC) classifies TEA as Group 3 (not classifiable as to its carcinogenicity to humans), citing inadequate evidence from animal studies and lack of human data.^[62]^[63]^[64]^[65] Human exposure to TEA primarily occurs dermally, with low absorption rates through intact skin, typically less than 1% of the applied dose reaching systemic circulation in in vitro human skin models. Inhalation and oral routes are less common but relevant in occupational settings, where the American Conference of Governmental Industrial Hygienists (ACGIH) recommends a threshold limit value (TLV) of 5 mg/m³ as an 8-hour time-weighted average to prevent irritation and systemic effects.^[66]^[23]^[67] Human case studies of adverse effects are rare and mostly involve allergic contact dermatitis. Reports include reactions to TEA in eardrops causing otitis externa-like symptoms and in sunscreens leading to eczematous eruptions on sun-exposed skin, confirmed by positive patch tests at 5% concentration. These cases highlight TEA's role as an infrequent but possible allergen in topical products.^[68]^[69]^[70]

Environmental impact

Triethanolamine enters the environment primarily through wastewater discharges from cosmetics manufacturing and metalworking fluid applications, where it is used as a surfactant, pH adjuster, and corrosion inhibitor.^[14] ^[71] Limited releases can also occur during its industrial synthesis via distillation processes.^[71] In aquatic ecosystems, triethanolamine demonstrates low acute toxicity to fish, with LC₅₀ values typically ranging from 1,000 to 11,800 mg/L over 96 hours, indicating minimal short-term risk at environmentally relevant concentrations.^[72] However, it exhibits higher sensitivity in algae and invertebrates; acute EC₅₀ values are approximately 512 mg/L for algae growth inhibition over 72 hours and 610 mg/L for invertebrate immobilization over 48 hours.^[72] ^[73] Ecotoxicological studies reveal sub-chronic effects on Daphnia magna reproduction, with a no-observed-effect concentration (NOEC) of 125 mg/L in a 21-day exposure test, though mortality occurs at lower thresholds around 16 mg/L.^[74] Triethanolamine is readily biodegradable under aerobic conditions, achieving greater than 70% degradation within 28 days according to OECD 301 guidelines, with specific tests showing 96% mineralization to CO₂ after 19 days via microbial processes.^[74] ^[75] Its low bioaccumulation potential, evidenced by a log K_ow of -1.0 to -2.5, ensures it does not concentrate in food chains or aquatic organisms.^[1] ^[72] Due to its high water solubility (>100 g/L) and negative log K_ow, triethanolamine displays moderate to high mobility in soil, facilitating potential leaching into groundwater from contaminated industrial effluents.^[1] ^[76] This mobility is particularly pronounced in soils with low organic carbon or clay content, raising concerns for aquifer contamination in areas with inadequate wastewater treatment.^[76]

Regulatory status

Triethanolamine (TEA) is regulated under Annex III of the EU Cosmetics Regulation (EC) No 1223/2009, which restricts its use in cosmetic products to a maximum concentration of 2.5% in leave-on preparations and 5% in rinse-off products to minimize irritation risks.^[32] In the United States, the FDA lists TEA as generally recognized as safe (GRAS) for use as an indirect food additive in accordance with 21 CFR 177.2600 for components of articles intended for repeated use, but it is not approved for direct addition to food.^[77] Occupational exposure to TEA is governed by the OSHA permissible exposure limit (PEL) of 5 mg/m³ as an 8-hour time-weighted average (TWA) to protect against respiratory and dermal effects.^[78] Under the EU REACH regulation, TEA (CAS 102-71-6) is registered, with derived no-effect levels (DNELs) established for workers, including a long-term dermal DNEL of 2.7 mg/kg body weight/day based on toxicokinetic and toxicodynamic data. In the environmental domain, TEA is included on the EPA's Toxic Substances Control Act (TSCA) Inventory as an existing chemical substance subject to reporting and recordkeeping requirements under 40 CFR Part 704.^[79] Wastewater discharges containing TEA are regulated under the Clean Water Act through effluent limitations guidelines for the organic chemicals, plastics, and synthetic fibers manufacturing point source category (40 CFR Part 414), which impose technology-based limits on conventional pollutants and may require best available technology for toxic pollutants like amines.^[80] TEA is classified under Schedule 3, Part B of the Annex on Chemicals in the Chemical Weapons Convention as a precursor (entry 3B17) due to its potential role in the synthesis of nitrogen mustards like HN-3.^[81] As of 2025, the European Chemicals Agency (ECHA) harmonized classification for TEA includes Eye Dam. 1 (H318) and Repr. 2 (H361f), with ongoing monitoring for potential nitrosamine formation under REACH and cosmetics regulations, though no outright bans have been implemented.^[3] The Cosmetic Ingredient Review (CIR) Expert Panel's initial safety assessment in 1983 concluded that TEA is safe in cosmetic formulations designed for discontinuous, brief use followed by thorough rinsing, with concentrations not exceeding 5%. This assessment was reopened and updated in 2013 (based on 2010-2013 data reviews), reaffirming safety for rinse-off products at concentrations below 5% when formulated to be nonirritating and to avoid nitrosamine formation.^[23]

References

[1]
Triethanolamine | C6H15NO3 | CID 7618 - PubChem - NIH
Triethanolamine is a tertiary amino compound that is ammonia in which each of the hydrogens is substituted by a 2-hydroxyethyl group.
[2]
[PDF] BLUE TEA CIR EXPERT PANEL MEETING SEPTEMBER 26-27, 2011
Sep 1, 2011 · Triethanolamine (TEA) and diethanolamine (DEA) should not be used in products containing N-nitrosating agents. December 2010: a formal rereview ...
[3]
nitrilotriethanol - Substance Information - ECHA
TRIETHANOLAMINE COMMERCIAL LOW FREEZING GRADE (PM-4447). Registration dossier. TRIETHANOLAMINE, 99%. Registration dossier. TRIETHANOLAMINE, Commercial Grade.
[4]
https://pubchem.ncbi.nlm.nih.gov/compound/Monoethanolamine
[5]
https://pubchem.ncbi.nlm.nih.gov/compound/Diethanolamine
[6]
Trolamine: Uses, Interactions, Mechanism of Action | DrugBank Online
Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties ...Missing: hydrophilic | Show results with:hydrophilic<|control11|><|separator|>
[7]
Write a net ionic equation to show that triethanolamine, C6H | Quizlet
Write a net ionic equation to show that triethanolamine, C X 6 H X 15 O X 3 N \ce{C6H15O3N} CX6HX15OX3N, behaves as a Bronsted-Lowry base in water.
[8]
Triethanolamine hydrochloride | C6H16ClNO3 | CID 101814
Triethanolamine hydrochloride is a hydrochloride obtained by combining triethanolamine with one equivalent of hydrogen chloride. It has a role as a surfactant.
[9]
Triethanolamine nitrate | C6H16N2O6 | CID 33700 - PubChem - NIH
Triethanolammonium nitrate is an organoammonium salt resulting from the mixing of equimolar amounts of nitric acid and triethanolamine.
[10]
Effect of triethanolamine chelating agent on crystallinities, phase ...
Mar 15, 2022 · The current study reports the successful preparation of high crystallinity and purity of ZnAl 2 O 4 via thermal decomposition of the metal complex precursor.
[11]
Synthesis of Nanocrystalline α-Alumina Power Using Triethanolamine
Aug 9, 2025 · Triethanolamine (TEA) has been used as a chelating agent along with metals like Ce [5], Al [6] , Cu [7], Cd [8] to produce a single-source ...
[12]
Thermal decomposition of cerium triethanolamine complexes
The thermal decomposition of cerium triethanolamine complexes starts around 200°C, has multiple stages, and ends at 350°C in air or higher in inert atmosphere, ...
[13]
Triethanolamine | 102-71-6 - ChemicalBook
Jun 13, 2025 · It is alkaline, being irritating. It has a melting point of 21.2 °C, the boiling point of 360 °C, a flash point of 193 ° C, the relative density ...
[14]
Toxic Pollutant Identification: Amination Processes - epa nepis
The first commerical production of triethanolamine was in 1928, followed by large scale production of mono- and diethanolamines in 1931. The ethanolamines ...
[15]
Triethanolamine - an overview | ScienceDirect Topics
Triethanolamine ; Specific gravity, g cm · 1.126 ; Specific gravity temperature, °C · 20 ; Vapor density, air=1, 5.10 ; Vapor pressure, kPa, 0.0001333.
[16]
Triethanolamine - Some Industrial Chemicals - NCBI Bookshelf
Ethanolamines became available commercially in the early 1930s; they assumed steadily growing commercial importance as intermediates after 1945, because of the ...Missing: commercialization | Show results with:commercialization
[17]
Triethanolamine Market CAGR To Hit 4.8% by 2034 - Market.us News
According to the United Nations Environment Programme, global TEA production in 1999 ranged from 100,000 to 500,000 tonnes annually. In the United States, ...
[18]
Triethanolamine Market Size, Share, Analysis & Forecast 2035
The global Triethanolamine (TEA) market stood at approximately 518 thousand tonnes in 2024 and is expected to grow at a healthy CAGR of 2.78% during the ...Missing: commercialization | Show results with:commercialization
[19]
Triethanolamine Market Size, Share & Trends | Forecast [2032]
The global Triethanolamine market size is projected to grow from $1.40 billion in 2025 to $1.98 billion by 2032, at a CAGR of 5.1% during 2025-2032.
[20]
Triethanolamine (TEA) Prices, News, Chart and Demand
The Triethanolamine (TEA) Prices in the United States for Q1 2025 reached 1250 USD/MT in March. Prices rose due to stable demand and limited supply.Missing: tonne | Show results with:tonne
[21]
Triethanolamine Production Volume, Price Range, Demand and ...
Jul 29, 2024 · The United States is the leading global exporter of triethanolamine, with an average annual export volume of 65 Kiloton from 2016-2023.Missing: 2020s | Show results with:2020s
[22]
Triethanolamine and TEA-Containing Ingredients - Cosmetics Info
Triethanolamine (TEA) is a clear, colorless to pale yellow liquid used in makeup, fragrances, hair care, and as a pH adjuster in cosmetics.Missing: emulsifier | Show results with:emulsifier
[23]
Safety Assessment of Triethanolamine and ... - Sage Journals
The TEA is reported to function as a surfactant or pH adjuster; the related TEA-containing ingredients included in this safety assessment are reported to ...<|separator|>
[24]
Triethanolamine - Personal Care & Cosmetics - UL Prospector
Triethanolamine is an organic compound used to elevate pH in cosmetics, stabilize emulsions, fragrances, preservatives, and acts as a foam stabilizer.
[25]
Triethanolamine Uses in Skin Care Products - Bell Chem
Mar 17, 2025 · Triethanolamine acts as an emulsifier, pH adjuster, stabilizer, surfactant, and thickener in skincare products.
[26]
Triethanolamine 280 | MakingCosmetics
Triethanolamine - Stabilizer & pH Balancer for cosmetics and skin care products. ... Acts as foam stabilizer as it has detergent properties and stabilizes ...
[27]
https://russellorganics.com/pages/triethanolamine-in-skincare
[28]
Otic Preparations - GlobalRPH
Sep 1, 2017 · Mechanism of Action CERUMENEX Eardrops emulsify and disperse excess or impacted earwax. The triethanolamine polypeptide oleate, a surfactant, ...
[29]
Triethanolamine polypeptide oleate otic Uses, Side Effects & Warnings
Triethanolamine polypeptide oleate otic is used in the ear to break down and loosen earwax that has built up inside the ear canal.
[30]
TRIETHANOLAMINE (TEA) - Ataman Kimya
Some common products in which triethanolamine is found are sunscreen lotions, liquid laundry detergents, dishwashing liquids, general cleaners, hand sanitizers,
[31]
What is the mechanism of Trolamine? - Patsnap Synapse
Jul 17, 2024 · This unique combination allows Trolamine to act as a buffer, emulsifier, and pH adjuster. The presence of hydroxyl groups (-OH) and amine groups ...
[32]
[PDF] Memorandum To: CIR Expert Panel Members and Liaisons From
Nov 18, 2010 · Triethanolamine (TEA), an ingredient that functions as a fragrance ingredient, surfactant – emulsifying agent, and. pH adjuster in cosmetic ...
[33]
https://www.sigmaaldrich.com/US/en/product/sigma/t0449
[34]
Triethanolamine 85% & 99% - Wintersun Chemical
It is used as a neutralizing agent in water-based coatings, as a chain lengthener in polyol-based polyurethane foams and elastomers, as a neutralizing agent in ...Missing: printing | Show results with:printing
[35]
The role and application of triethanolamine in metalworking fluids
Aug 15, 2025 · Triethanolamine itself is a water-soluble rust inhibitor. Used alone, it effectively prevents rust on steel in the short term, typically at a ...
[36]
Protection Efficiency of Triethanolamine Decanedioate as a Water ...
Triethanolamine carboxylates, particularly triethanolamine decanedioate (TEA·C10), are widely employed as corrosion inhibitors for steel in aqueous ...<|separator|>
[37]
Water-based ink set and inks and their use - Google Patents
Ink set according to one of the preceding claims, characterized, that the inks (T2, T3, T4, T...) as a further additive (ZS) Triethanolamine (TEA) included.
[38]
Triethanolamine (TEA) | Dow Inc.
It is commonly used as a cement grinding aid, and can be used in other applications as well. Uses. Gas sweetening; Detergents; Cleaners; Concrete admixtures ...
[39]
The role of triethanolamine - Knowledge
Jun 2, 2022 · It can be used as an emulsifier for oils and waxes, a rust inhibitor, an acid gas absorbent and a wetting agent for daily chemicals.Missing: polishes | Show results with:polishes
[40]
Reaction mechanism of halogenated rubber crosslinking using a ...
Iron (III) acetylacetonate (Fe (acac)) in the presence of triethanolamine (TEOA) was utilized as a novel crosslinking agent for halogenated diene rubber.Missing: epoxy | Show results with:epoxy<|separator|>
[41]
TRIETHANOLAMINE - Ataman Kimya
Triethanolamine's structure has a hydrophilic side and a hydrophobic side. Hydrophilic means it binds to water and hydrophobic means it binds to oil.
[42]
Sustainable Cement Production: TEA-TIPA as Grinding Aids - MDPI
This suggests that higher dosages enhance the impact-grinding mechanism, where the lubricant effect of the additive dominates, thereby improving grinding medium ...
[43]
Effect of modified Triethanolamine on grinding efficiency and ...
This paper seeks to improve through esterification the efficiency of triethanolamine (TEA) molecules used in the cement grinding industry.
[44]
[PDF] A study of different grinding aids for low- energy cement clinker ...
Grinding aids can improve production and fineness and decrease energy consumption by reducing the agglomeration of particles and protecting the balls and liners ...
[45]
Start Manufacturing Business of Grinding Aids from Triethanolamine
The earliest patents from the 1930s tested and used powdered mixtures of mineral oil, animal oil, and petroleum cracking residues to enhance cement's high ...
[46]
US3655461A - Flux for aluminum soldering - Google Patents
A flux for soldering metals including non-ferrous metals comprising: 45 70 percent epoxide resin, 15 30 percent rosin, l2 18 percent triethanolamine, and 3 7 ...
[47]
Surfactant composition for use in gypsum wallboard manufacture
[0003] In the production of gypsum board, an aqueous core slurry composed ... triethanolamine. In some preferred embodiments, the cation is sodium or ...
[48]
Selective masking and demasking for the stepwise complexometric ...
Mar 6, 2008 · Procedure To determine aluminium, 20 mL of triethanolamine and 5 mL of hydroxyl amine 10% (w/v) were added to the solution remaining after the ...
[49]
The use of triethanolamine in a buffer for the determination of ...
Interference by complex-forming metal ions is avoided by the use of a citric acid-triethanolamine buffer, pH < 7.5.
[50]
Sensitizing agent for photographic emulsions - Google Patents
A photographic sensitive element comprising a silver halide emulsion layer, said emulsion containing triethanolamine. ... stabilizing photographic material ...
[51]
Color-selective holographic retroreflector array for sensing ... - Nature
Sep 5, 2016 · The gelatin holographic plates were pre-swollen by immersing them in a bath of aqueous solution of triethanolamine (10%, v/v) for 1 min and then ...
[52]
[PDF] Holographic Optical Element Materials Research. - DTIC
We investigated holographic properties produced by the swelling control of gelatin films with the multi—functional organic compound triethanolamine. Reflection ...<|separator|>
[53]
Depositing Rate of Electroless Nickel Plating Bath Contained ...
Decreasing or increasing concentration of triethanolaminc as a complexing agent , the depositing rate is decreased and when the bath contained 25-50mL/L of ...
[54]
Composition and mechanical properties of nickel deposit obtained ...
Jun 1, 1986 · Composition and mechanical properties of nickel deposit obtained from electroless nickel plating bath contained triethanolamine as complexing ...Missing: chelating electronics
[55]
Grease-like coupling agent based on metal ionization method for ...
It is necessary to improve the sound transmission effect of grease-like coupling agents for industrial ultrasonic NDT. ... triethanolamine, ethylene glycol, and ...
[56]
ICSC 1034 - TRIETHANOLAMINE - INCHEM
The substance is a weak base. Reacts with oxidants. Decomposes on burning. This produces toxic and corrosive fumes including nitrogen oxides. Formula: C6H15 ...
[57]
Skin sensitizing properties of the ethanolamines mono‐, di‐, and ...
Apr 24, 2009 · Therefore, the risk of sensitization to TEA seems to be very low. MEA and DEA were patch tested in a much more aimed fashion in 9602 and 8791 ...
[58]
Skin Sensitizing Properties of the Ethanolamines Mono-, Di-, and ...
The profile of patch test reactions indicates a slightly irritant potential rather than a true allergic response in many cases. Although used widely, no ...
[59]
Allergic contact dermatitis to cosmetics: retrospective analysis of a ...
Another positive allergen in the tests was triethanolamine, an emulsifier used in cosmetics and topical medications, positive in 2.1% of cases, a value below ...
[60]
[PDF] Diethanolamine Triethanolamine
Critical effect. Medium - Acute and chronic critical effects were mild and potential critical effects similar. - DEA and TEA caused similar critical effects.
[61]
[PDF] Opinion on Nitrosamines and Secondary Amines in Cosmetic Products
Dec 13, 2011 · SCCS. The Committee shall provide opinions on questions concerning all types of health and safety risks (notably chemical, biological, ...
[62]
[PDF] Triethanolamine (CASRN 102-71-6) in B6C3F1 Mice (Dermal Studies)
These studies are designed and conducted to characterize and evaluate the toxicologic potential, including carcinogenic activity, of selected chemicals in ...
[63]
[PDF] TR-449: Triethanolamine (CASRN 102-71-6) in F344 Rats and ...
These studies are designed and conducted to characterize and evaluate the toxicologic potential, including carcinogenic activity, of selected chemicals in ...
[64]
Evaluation of the Potential of Triethanolamine to Alter Hepatic ...
It was concluded that TEA may cause liver tumors in mice via a choline-depletion mode of action and that this effect is likely caused by the inhibition of ...
[65]
[PDF] TRIETHANOLAMINE 1. Exposure Data - IARC Publications
1.1.3. Chemical and physical properties of the pure substance. (a) Description: Hygroscopic crystals, or colourless, viscous liquid with a mild.
[66]
In Vitro Absorption of Triethanolamine Through Human Skin
The percent of the applied dose of TEA absorbed into the receptor fluid was similar with both 1% and 5% TEA formulations. Absorption of TEA was reduced by ...
[67]
[PDF] osha-pv2141.pdf - Triethanolamine
ACGIH TLV: Procedure: Recommended sampling time and sampling rate: Reliable quantitation limit: Status of method: December 2008. PV2141. 1.0. 5 mg/m3 none. 5 mg ...
[68]
Allergic contact dermatitis from triethanolamine polypeptide oleate ...
Allergic contact dermatitis from triethanolamine polypeptide oleate condensate in eardrops and shampoo. Contact Dermatitis. 2005 Apr;52(4):233. doi: 10.1111 ...Missing: human studies reactions sunscreen
[69]
Allergic contact dermatitis from triethanolamine in a sunscreen
Allergic contact dermatitis from triethanolamine in a sunscreen ... Contact Dermatitis. 2001 Jan;44(1):41-2. doi: 10.1034/j.1600-0536.2001.440107-8.x.Missing: human studies reactions eardrops
[70]
Triethanolamine allergy inadvertently discovered from a fluorescent ...
Triethanolamine is used as an emulsifier in many topical preparations and is an infrequent cause of contact allergy. We report a case of a woman with a ...
[71]
[DOC] COVER PAGE - OECD Existing Chemicals Database
Release of triethanolamine during production can occur from the production of ethanolamine crude and subsequent distillation to give the triethanolamine ...
[72]
[PDF] Safety Data Sheet: Triethanolamine - Carl ROTH
Triethanolamine ≥99 %, for synthesis article number: 6300. Version: 4.1 en ... Dynamic viscosity. 930 mPa s at 20 °C. Solubility(ies). Water solubility.
[73]
[PDF] 02318_003_en_ TRIETHANOLAMINE 99%
a) Acute aquatic toxicity: LC50 Fish = 11800 mg/L 96h a) Acute aquatic toxicity: EC50 Algae = 512 mg/L 72h. Crustacean toxicity: Crustacean NOEC = 16 mg/L 504.
[74]
[PDF] Triethanolamine July 2021 | Santos
Biodegradation. Triethanolamine is readily biodegradable. In an OECD 301E test, there was 96% degradation after 19 days (ECHA). [Kl. score = 2].
[75]
[PDF] SAFETY DATA SHEET - Neutronco
. Acute toxicity (represents short term exposures with immediate effects - no chronic/delayed effects known unless otherwise noted). Acute oral toxicity. Very ...
[76]
Titania-triethanolamine-kaolinite nanocomposites as adsorbents ...
Additionally, it is highly mobile in soils with low levels of clay and organic carbon, so it can potentially contaminate aquifers particularly because it is ...
[77]
Inventory of Food Contact Substances Listed in 21 CFR - FDA
TRIETHANOLAMINE. Consult the regulation(s) cited below to see if your substance is authorized for your intended use. CAS ...
[78]
[PDF] SAFETY DATA SHEET - Fisher Scientific
Nov 3, 2010 · OSHA PEL. NIOSH IDLH. Mexico OEL (TWA). Triethanolamine. TWA: 5 mg/m3. TWA: 5 mg/m3. Diethanolamine. TWA: 1 mg/m3. Skin. (Vacated) TWA: 3 ppm.
[79]
https://comptox.epa.gov/dashboard/dsstoxdb/results?search=DTXSID4020296
[80]
Clean Water Act Effluent Limitations Guidelines and Standards for ...
Mar 17, 2021 · Among its core provisions, the Clean Water Act (CWA) prohibits the discharge of pollutants from a point source to waters of the United States, ...
[81]
[PDF] Schedule 3 - Organisation for the Prohibition of Chemical Weapons
Scheduled Chemicals under the Chemical Weapons Convention (CWC). Guidelines ... Triethanolamine. 3B(17). Schedule 3 Part A, Toxic Chemicals. Schedule 3 ...