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RSV

RSV is a three-letter initialism with multiple meanings in various fields. In biology and medicine, it most commonly refers to , a common cause of respiratory infections, or , an avian . Other uses include organizations such as the Royal Society of , transportation terms like research support vessel, and miscellaneous items including the of the .

Biology and Medicine

Respiratory Syncytial Virus

Respiratory syncytial virus (RSV) is a highly contagious, single-stranded, negative-sense belonging to the genus in the family and order Mononegavirales. It exists in two major antigenic subtypes, A and B, which differ in their surface glycoproteins and contribute to annual epidemics through antigenic variation. Previously classified within the family alongside viruses like parainfluenza, RSV was reclassified in 2016 to reflect its distinct genetic and structural features. RSV is the leading cause of acute lower infections, including and , particularly in children under 1 year of age. Globally, RSV causes an estimated 33 million episodes of acute lower respiratory infections annually in children under 5 years, resulting in about 3.6 million hospitalizations and 100,000 deaths in this age group, with additional burden in older adults and other vulnerable populations. Nearly all children experience at least one RSV infection by age 2, though reinfections occur throughout life due to incomplete immunity. The virus poses higher risks of severe disease to premature infants, older adults aged 65 years and older, and immunocompromised individuals, who may develop complications like . Transmission primarily occurs through respiratory droplets from coughing or sneezing, as well as contact with contaminated surfaces, facilitating close-contact spread in households and communities. In temperate climates, RSV exhibits strong , with peaks during winter months from to March in the , driven by factors like low and indoor crowding. As of 2025, preventive options have expanded with FDA-approved RSV including GSK's Arexvy, Pfizer's Abrysvo, and Moderna's mResvia (approved 2024) for adults; CDC recommendations (as of 2025) include all adults 75 years and older and adults 50-74 at increased risk, with Abrysvo also recommended for pregnant individuals at 32-36 weeks to protect infants. These reduce severe RSV lower disease by up to 80% in clinical trials. For infants, the nirsevimab (Beyfortus), approved by the FDA in 2023, provides during the first RSV season, offering protection against hospitalization for up to 6 months. These advancements mark a significant step in mitigating RSV's burden on high-risk populations.

Rous Sarcoma Virus

The (RSV) is a replication-competent, oncogene-containing belonging to the genus Alpharetrovirus in the Retroviridae, known for inducing sarcomas in chickens and other avian species. It was first identified as a filterable capable of transmitting tumors between chickens, marking it as the inaugural demonstration of a causing solid tumors in vertebrates. Discovered by Peyton Rous in 1911 through experiments at the Rockefeller Institute, where cell-free filtrates from a chicken sarcoma induced tumors in healthy birds, RSV challenged prevailing views on cancer etiology and established viral oncogenesis as a field of study. Rous's findings, published in the Journal of Experimental Medicine, were initially met with skepticism but later recognized as groundbreaking, earning him the Nobel Prize in Physiology or Medicine in 1966 for discovering tumor-inducing viruses. This virus remains the prototype for avian retroviruses and the first oncovirus described. RSV possesses a single-stranded, positive-sense RNA genome approximately 9.3 kilobases in length, organized into four primary open reading frames: gag (encoding capsid proteins), pol (encoding reverse transcriptase and integrase), env (encoding envelope glycoproteins), and src (encoding a tyrosine kinase oncoprotein). The v-src oncogene, acquired from the host during viral evolution, drives cellular transformation by constitutively activating signaling pathways that promote uncontrolled proliferation and inhibit apoptosis, distinguishing RSV from non-oncogenic retroviruses. As an experimental model, RSV has been instrumental in elucidating mechanisms of viral oncogenesis, including how oncogenes disrupt normal cell regulation to induce malignancy. Its v-Src protein was pivotal in the 1970s discovery of protein kinases, revealing their role in and linking viral proteins to eukaryotic growth control pathways. Although RSV does not infect humans and is restricted to hosts, its study has profoundly shaped research, including insights into integration and replication strategies applicable to lentiviruses like .

Organizations

Royal Society of Victoria

The Royal Society of Victoria (RSV) was founded in 1854 in , , as the Philosophical Society of Victoria, a dedicated to promoting scientific knowledge, , and art for the benefit of the community. Three years after 's separation from , the society emerged amid the colony's rapid growth during era, drawing inspiration from the established in 1660. In 1855, it merged with the Victorian Institute for the Advancement of Science, and in 1859, it received royal assent to become the Royal Society of Victoria, coinciding with the opening of its historic building at 8 La Trobe Street, designed by architect Joseph Reed. This venue has since served as a hub for scientific discourse, hosting early discussions on Melbourne's , including its , , and systems. Historically, the RSV played a pivotal role in advancing exploration and natural history in . It commissioned the in 1860 to survey inland regions and contributed to biological surveys of Bay, fostering understanding of Victorian . In 1886, the society established the Australian Antarctic Exploration Committee, marking the first organized Australian effort toward scientific investigation and laying groundwork for later expeditions. The RSV has published the Proceedings of the Royal Society of Victoria annually since 1855, documenting research across disciplines from geology to . Key activities include hosting public lectures, seminars, and events through initiatives like Inspiring and National Science Week, which engage communities in and . The society administers awards such as the RSV Research Medal for excellence in scientific research and the Young Scientist Research Prizes for doctoral candidates in fields like biomedical, biological, earth, and physical sciences, recognizing emerging talent with monetary prizes and certificates. Membership is open to individuals, organizations, schools, and enthusiasts across and the region interested in and , with categories including fellows appointed for significant contributions. The RSV collaborates with bodies like Science & Technology and participates in networks such as Australia's Royal Societies, supporting broader scientific advancement. As of 2025, the RSV emphasizes public outreach, education, and research on pressing issues like , through programs that build science literacy in regional areas and partner with schools for hands-on initiatives. It continues to operate from its heritage-listed building, renovated to serve as Victoria's premier hub, while expanding online platforms for virtual engagement.

Réseau Santé Valais

The Réseau Santé Valais, now known as Hôpital du Valais, was established on , 2004, in the canton of , , through the merger of ten hospitals and clinics to form an integrated network of healthcare providers, including facilities, ambulatory services, and coordination. This structure was created under cantonal legislation to unify fragmented hospital policies across the region's thirteen districts, addressing historical inefficiencies in delivery. The network's primary objectives are to enhance coordinated care, optimize resource sharing, and improve access to health services for the canton's approximately 371,000 residents (as of ), particularly in its challenging mountainous terrain where geographic barriers can hinder timely medical attention. It serves as the reference institution for the hospital component of Valais's , providing 24/7 in both and settings while aligning with federal and cantonal health policies. Key components include major hospital sites such as those in (central administration), , , and Brigue, which collectively employ over 6,200 staff and handle more than 650,000 ambulatory visits and 41,500 inpatient admissions annually. The network emphasizes telemedicine initiatives, such as remote consultations with specialists for emergency support, and robust emergency response systems, including a dedicated non-vital medical emergencies line (0848 200 300). Among its achievements, the Réseau Santé Valais has improved chronic disease management through integrated care programs and specialized consultations, as demonstrated by initiatives like symposia on nursing expertise for chronic conditions and dedicated services for respiratory and palliative care. It also coordinated an effective pandemic response during COVID-19, reactivating a crisis cell for hospital management, implementing vaccination rollouts starting with geriatric patients, and developing post-COVID care consultations. Governance is structured as an autonomous public institution under cantonal oversight, operating as a non-profit entity with a seven-member appointed by the State Council of , alongside a general directorate responsible for operational and strategic decisions, including budget approval and . This framework incorporates public-private partnerships, such as collaborations with private clinics for expanded capacity during peaks in demand.

Transportation

Research Support Vessel

Research support vessels (RSVs) are multi-purpose maritime platforms engineered primarily for oceanographic research, logistical support to remote scientific stations, and deployment of submersible equipment such as remotely operated vehicles (ROVs) and autonomous underwater vehicles (AUVs). These vessels facilitate extended expeditions in challenging marine environments, including polar regions, by combining research capabilities with supply functions like transporting personnel, equipment, and provisions to isolated bases. Unlike general cargo ships, RSVs are optimized for scientific operations, featuring specialized laboratories, winches for deploying sensors, and storage for samples. Common features of RSVs include ice-strengthened hulls to navigate frozen waters, helipads for operations in remote areas, and systems that use thrusters and GPS to maintain precise station-keeping without anchors, essential for stable over seabeds. These vessels typically measure 50 to 160 meters in length, with displacements ranging from 10,000 to 25,000 tons, allowing them to carry substantial cargo while accommodating 30 to 50 and crew. systems often incorporate diesel-electric setups for efficiency in varying conditions, and many are rated for icebreaking up to 1.5-2 meters thick. A notable example is the German RV Polarstern, commissioned in 1983 and operated by the Institute, which serves and missions focused on studies, , and . At 118 meters long with a double-hulled, ice-strengthened design capable of breaking 1.5-meter-thick ice, Polarstern supports the Neumayer III station in by delivering supplies and enabling on-site experiments during year-round voyages of up to 80 days. It features two helicopters for aerial surveys and deploys ROVs for deep-sea sampling, contributing to high-impact research like the MOSAiC expedition on sea ice dynamics. In operational roles, RSVs handle for polar bases—such as resupplying , , and scientific gear—while conducting direct research like hydrographic surveys, assessments, and in extreme conditions where traditional ships cannot operate. They deploy submersibles for and collect on ocean currents, temperature, and ecosystems, often in collaboration with international programs. Military adaptations occasionally repurpose similar vessels for dual-use scientific and tasks, such as hydrographic . As of 2025, the evolution of RSVs emphasizes , with increasing adoption of green technologies like diesel-electric and battery systems to reduce emissions and fuel consumption during long deployments. For instance, Australia's RSV Nuyina, launched in 2021, integrates for quieter, more efficient operations in waters, supporting both resupply and while minimizing environmental impact. Newer designs, such as the successor to Polarstern, incorporate advanced eco-certifications and low-carbon features to align with global decarbonization goals in polar science.

Reconnaissance Scout Vehicle

The Reconnaissance Scout Vehicle (RSV), also known as a , is a lightweight, wheeled or tracked designed for forward observation, gathering, and in combat zones, emphasizing and over heavy armament. These vehicles typically feature modular armor for protection against and , advanced sensors such as thermal imaging and long-range for , low acoustic signatures to avoid detection, and a of 2 to 4 personnel to facilitate rapid deployment and operation. The design prioritizes speed and agility, often with four-wheel or eight-wheel drive configurations, allowing navigation across varied terrain while minimizing vulnerability in hostile environments. Historical examples illustrate the evolution of RSVs, with the British scout car serving as a seminal wheeled model from the 1950s to the . Produced by Daimler between 1952 and 1971, the was a 4x4 armored vehicle with a crew of two, equipped with a for and used extensively in conflicts such as the and for patrol and observation duties. In modern contexts, the U.S. Army's M1127 represents an advanced variant, featuring an eight-wheeled platform with the Long-Range Advanced (LRAS3) for day/night imaging and a crew of three plus four dismounts, deployed since the early in operations like those in and . RSVs fulfill critical roles in operations, including perimeter patrol to secure flanks, through collection, and with unmanned aerial vehicles (UAVs) to extend range beyond line-of-sight limitations. These vehicles enable commanders to gather tactical information on enemy positions, terrain suitability, and environmental factors without committing larger forces, often operating ahead of main units to shape the . As of 2025, current developments in RSVs emphasize unmanned and variants to reduce personnel risk in contested areas, with the U.S. Army awarding contracts for unmanned systems (UxS) to enhance remote capabilities. Programs like the Multi-Functional Company integrate ground vehicles with short-range UAS, focusing on AI-driven navigation and for persistent in large-scale combat operations.

Other Uses

Revised Standard Version

The (RSV) is an English translation of the published by the National Council of the Churches of Christ in the USA, serving as a revision of the of 1901, which itself revised the King James Version of 1611. The project was authorized in 1937 by the International Council of Religious Education and involved an ecumenical committee of 32 scholars from Protestant denominations, later expanded to include Catholic and international representatives, working under the oversight of an advisory board of 50 members. The appeared in 1946, the complete Old and New Testaments in 1952, and a second edition of the in 1971, with the / added in 1957. The RSV adheres to a formal equivalence translation philosophy, aiming to render the original Hebrew, Aramaic, and Greek texts as literally as possible while updating archaic expressions from earlier English versions into dignified, idiomatic suitable for public worship and private reading. This approach preserves the literary quality and theological precision of the Tyndale-King James tradition, incorporating advances in , such as reliance on the for the and early Greek manuscripts for the , without introducing paraphrastic liberties. The translation emphasized interconfessional and fidelity to the plain meaning of the source texts, avoiding sectarian biases. Key editions include the (RSV-CE), first published in 1966 by a committee of the Catholic Biblical Association of America, which incorporated the in their traditional Catholic order and received ecclesiastical approval for liturgical use. This was followed by the (NRSV) in 1989, an update that refined phrasing for clarity and introduced limited where the original texts supported it. The RSV has exerted significant influence in Protestant churches, academic study, and ecumenical settings, with over 55 million copies sold by 1990, establishing it as a standard for scholarly reference and liturgical reading. It remains valued for its balance of accuracy and readability, though it has faced criticisms from conservative groups for renderings perceived as deviating from traditional interpretations, such as in Isaiah 7:14. Subsequent updates, including the NRSV and the 2021 New Revised Standard Version Updated Edition (NRSVue), have addressed archaic language and expanded inclusive revisions to better reflect contemporary scholarship and sensibilities as of 2025.

Rainbow Six Vegas

Tom Clancy's Rainbow Six: Vegas is a tactical video game developed by and published by . It was first released on November 20, 2006, for , followed by the PC version on November 28, 2006, and the version on June 26, 2007. A , Tom Clancy's Rainbow Six: Vegas 2, was released in March 2008 for consoles and April 2008 for PC. The game's narrative is set in Las Vegas, Nevada, where players control a Rainbow operative leading a counter-terrorism team against international terrorists led by Irena Morales and her mercenaries. As part of the Tom Clancy's Rainbow Six series, it emphasizes high-stakes operations in urban environments, including iconic Las Vegas landmarks like casinos and the Strip. Core gameplay revolves around realistic SWAT-style tactics, where players issue commands to AI-controlled teammates, customize weapons with attachments, and engage in a single-player campaign with branching mission paths. Multiplayer modes support team-based adversarial play, including and objective-driven scenarios, with progression systems unlocking gear. The game introduced innovations such as dynamic Vegas-themed environments, like neon-lit casinos that influence tactical positioning and sightlines. Enemy AI features advanced behaviors, including flanking and coordinated assaults, while the cover system allows leaning and rappelling for strategic engagements, though destructible elements are limited to specific interactive objects. As of 2025, Rainbow Six: Vegas has influenced modern tactical shooters through its emphasis on cover mechanics and team coordination, elements refined in the series' continuation, (2015). Ongoing fan discussions highlight interest in a potential to update its visuals and online features for current platforms.

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