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Accessory bone

An accessory bone, also known as an accessory ossicle or supernumerary bone, is a secondary ossification center that fails to fuse with the adjacent primary bone during skeletal development, resulting in an extra, well-corticated bony structure that is a normal anatomical variant.^[1] These bones differ from sesamoid bones, which are embedded within tendons to reduce friction and improve mechanical leverage, whereas accessory ossicles are typically separate from soft tissues and serve no known functional role.^[1] They are usually small, round, or ovoid in shape and appear as distinct entities on imaging, often identified incidentally during radiographic evaluations.^[1] Accessory ossicles occur throughout the body but are most prevalent in the foot and ankle, where approximately 40 distinct types have been described, representing the primary site for these variants in human anatomy.^[2] Common examples in the foot include the accessory navicular (prevalence 2%-21%), os trigonum (7%-25%), and os peroneum (up to 26%), while less frequent occurrences are noted in the wrist, elbow, knee, hip, and skull.^[1] In the upper extremity, such as the elbow, they are rarer, with reported incidences below 1% for specific types like the os supratrochleare dorsale.^[3] Prevalence varies by population and imaging modality, with anatomical dissections often revealing higher rates than radiographic studies due to detection limitations.^[1] Although accessory bones are typically asymptomatic and discovered incidentally, they can become clinically significant when subjected to trauma, repetitive stress, or degenerative processes, leading to conditions such as fractures, avascular necrosis, or impingement syndromes.^[2] For instance, an irritated accessory navicular may cause medial foot pain due to posterior tibialis tendon dysfunction, while an os trigonum can contribute to posterior ankle impingement during activities like ballet or soccer.^[1] Diagnosis relies on imaging—radiographs to confirm well-defined margins distinguishing them from fractures, with MRI or CT for assessing associated soft tissue pathology or complications.^[1] Management is usually conservative, involving rest, orthotics, or anti-inflammatory measures, though surgical excision is considered for persistent symptoms refractory to non-operative treatment.^[2]

Fundamentals

Definition and Characteristics

Accessory bones, also known as accessory ossicles, represent secondary ossification centers that fail to fuse with the primary skeletal elements during development, resulting in separate, well-formed bony structures. These ossicles are considered normal anatomical variants and are not associated with fractures, dislocations, or pathological processes.^[4]^[5] Morphologically, accessory bones are typically small, round, or ovoid in shape, with smooth, well-corticated margins and diameters commonly ranging from 2 to 10 mm, though sizes can vary slightly depending on location. They often appear as independent entities adjacent to standard bones, exhibiting mature bone density on imaging.^[6]^[7]^[4] Accessory bones must be distinguished from sesamoid bones, which are small, round structures that form within tendons to minimize friction during movement, such as the patella in the quadriceps tendon. In contrast, accessory ossicles derive from unfused ossification centers rather than tendon-embedded development.^[1]^[8]

Embryological Development

Accessory bones arise from ectopic or accessory ossification centers that develop separately from the primary ossification sites during the process of endochondral ossification in fetal development.^[6] These secondary centers form as variations in the normal ossification pathways, where cartilage models of future bones begin to mineralize and replace with bone tissue.^[9] Unlike primary centers, which integrate into the main bone structure, accessory centers fail to fuse completely, resulting in distinct ossicles that persist postnatally.^[10] The formation of these ossification centers typically occurs during the early fetal period, with initial bone ossification beginning between the sixth and seventh weeks of gestation.^[9] Genetic factors play a key role in this process, as variations in developmental genes can lead to the emergence of supernumerary ossification sites; for instance, studies on specific accessory bones like the navicular demonstrate heritable influences on their presence.^[11] Environmental influences, such as mechanical stress from fetal movements, may also modulate ossification by promoting or altering the fusion of these centers during growth.^[12] Failure of fusion often becomes evident by adolescence, when skeletal maturation completes and separate ossicles remain as stable structures.^[10] Histologically, accessory bones exhibit features akin to those of primary skeletal elements but on a smaller scale, consisting of a dense outer layer of cortical bone surrounding an inner core of cancellous bone with trabecular architecture.^[6] This composition provides mechanical integrity similar to regular bones, with well-defined cortical margins that distinguish them radiographically.^[9] The cancellous interior facilitates nutrient exchange through vascular channels, supporting the ossicle's viability without integration into larger bones.^[13]

Prevalence and Clinical Implications

Accessory bones, also known as accessory ossicles, exhibit varying prevalence across different anatomical regions and populations, with studies reporting an overall incidence of 2% to 30% in the general population depending on the location examined.^[14] In the foot and ankle, where they are most commonly studied, the prevalence ranges from 18% to 48%, with higher rates observed in specific ethnic groups; for instance, the accessory navicular bone occurs in up to 38% of East Asian individuals compared to 8% in North Americans.^[15]^[16] These variations are attributed to genetic and developmental factors, though exact mechanisms remain under investigation.^[17] Detection of accessory bones primarily occurs through imaging modalities such as plain radiographs, computed tomography (CT), and magnetic resonance imaging (MRI), often as incidental findings during evaluations for unrelated musculoskeletal complaints.^[18] Radiographs identify them in approximately 20-30% of routine foot scans, while advanced imaging like CT provides superior delineation of their morphology and relationships to adjacent structures, and MRI assesses associated soft tissue involvement.^[19] These ossicles can mimic acute fractures or avulsion injuries on initial imaging, necessitating careful radiographic interpretation to avoid misdiagnosis.^[4] Clinically, the vast majority of accessory bones remain asymptomatic throughout life, but in symptomatic cases—estimated at less than 10%—they may contribute to localized pain, joint impingement, or mechanical dysfunction due to trauma, avascular necrosis, or degenerative changes.^[7] For example, the accessory navicular has been associated with pes planus (flatfoot deformity) in some patients, potentially exacerbating arch collapse and hindfoot pain.^[20] They may also rarely correlate with conditions like tarsal coalition, where incomplete fusion involving ossicles can lead to rigid flatfoot or recurrent sprains, though direct causation is debated.^[21] Surgical intervention, typically involving excision of the symptomatic ossicle, is reserved for conservative treatment failures and yields pain relief in over 80% of cases, with success rates reaching 90-93% for procedures like the Kidner for accessory navicular syndrome.^[22]^[23] Postoperative outcomes emphasize the importance of addressing concurrent tendon or ligament issues to optimize recovery.^[24]

Cranial Accessory Bones

Wormian Bones

Wormian bones, also known as sutural or intra-sutural bones, are small, irregular ossicles that form within the sutures and fontanelles of the skull, most commonly along the lambdoid suture.^[25]^[26] These accessory bones arise from independent ossification centers and are typically asymmetrical and shapeless, often measuring less than 6 mm by 4 mm in size.^[27] They are predominantly located in the posterior aspect of the skull, with the lambdoid suture being the most frequent site (up to 27.89% of cases), followed by the lambda region (19.04%), while occurrences in the sagittal or coronal sutures are less common but possible.^[25]^[28] In the general adult population, the prevalence of Wormian bones varies widely by geographic and ethnic groups, ranging from approximately 10% in Caucasian populations to 40% in Indian populations and up to 80% in some East Asian groups, with studies reporting overall incidences around 35% in North Indian skulls.^[25]^[28] They are more frequently observed in males than females in certain cohorts, though no consistent gender association exists across all studies.^[25] In pathological conditions, their prevalence increases significantly; for instance, they occur in up to 96% of individuals with severe forms of osteogenesis imperfecta (types III and IV), compared to only 35% in milder type I.^[29] Clinically, Wormian bones are generally benign and considered normal variants that may enhance skull compliance and fracture resistance by distributing mechanical stress during bending loads.^[30] However, the presence of excessive numbers—defined as more than 10 to 15 bones, often in a mosaic pattern—can signal underlying syndromes, including osteogenesis imperfecta, Down syndrome, rickets, or pycnodysostosis, warranting further diagnostic evaluation such as imaging to differentiate from fractures.^[25]^[29] In forensic and anthropological contexts, they aid in sex estimation, population identification, and distinguishing sutural variants from traumatic injuries.^[27]

Inca Bone

The Inca bone, also known as the interparietal bone (os interparietale or os inca), is a triangular accessory ossicle situated in the interparietal region of the occipital squama, typically bounded by the lambdoid sutures superiorly and the mendosal suture inferiorly, with separation from the main occipital bone occurring via persistent transverse sutures.^[31]^[32] This structure arises from the failure of fusion between the primary (cartilaginous) and secondary (membranous) ossification centers—or among multiple intramembranous centers including two lateral plates and a median piece—of the occipital bone, which normally integrate during the second and third months of fetal development.^[31]^[33] The bone's morphology can vary, occasionally presenting as fragmented, multiple, or paired pieces, and it is distinct as a singular, larger entity compared to smaller sutural ossicles. It may represent an evolutionary remnant from reptilian postparietal bones integrated into the mammalian occipital squama.^[31]^[34] Prevalence of the Inca bone exhibits significant geographic and ethnic variation, ranging from approximately 1% in many modern populations (e.g., 1.3% in central India) to up to 30% in certain indigenous groups, such as pre-Hispanic South Americans (27.7%), Native Americans, and East Asian-derived populations like Tibetans and Sikkimese.^[31]^[35]^[36] In contrast, incidences are lower (under 5%) in European and Central Asian populations. This distribution underscores its value as an anthropological marker for tracing population migrations and affinities.^[35] Clinically, the Inca bone is typically asymptomatic and discovered incidentally during postmortem examinations, computed tomography (CT) scans, or radiographic imaging of the cranium.^[31] It holds relevance in radiology, where its sutural lines may mimic skull fractures, potentially leading to misdiagnosis, and in neurosurgery, as it could complicate procedures like burr-hole trephination near the occipital region.^[31] Forensically, its presence aids in individual identification, particularly when antemortem imaging is available, and contributes to ethnic profiling in medico-legal contexts. In rare cases, it has been associated with cranial deformities such as those seen in craniosynostosis syndromes.^[31]^[37]^[38]

Upper Extremity Accessory Bones

Os Acromiale

Os acromiale is an accessory bone formed by the incomplete fusion of one or more ossification centers of the acromion process on the scapula, resulting in a mobile distal segment connected by fibrocartilage. The acromion typically develops from four primary ossification centers—pre-acromion (anterior tip), meso-acromion (middle segment), meta-acromion (posterior segment), and basi-acromion (proximal base attached to the scapular spine)—which fuse progressively between ages 15 and 25. Non-fusion creates instability at the shoulder girdle, potentially altering deltoid mechanics and subacromial space dynamics.^[39]^[40] The condition is classified based on the unfused segment: pre-acromiale (involving the pre-acromion, least common at about 4%), meso-acromiale (involving the meso-acromion, most prevalent at 68–94% of cases), and meta-acromiale (involving the meta-acromion, rare at around 1–2%). Meso-acromiale predominates due to the larger size and later fusion of the meso-acromion center, with the unfused ossicle averaging 23 mm in length, 24 mm in width, and 10 mm in thickness.^[41]^[40] Prevalence of os acromiale ranges from 1% to 15% globally, with an estimated average of 8% based on anatomical studies of over 1,000 scapulae, though rates vary by ethnicity—higher in African and African American populations (9.2–18.2%) compared to Caucasians (1–15%, often around 1.9–7.7%) and Asians (0.7%). It occurs more frequently in males and can be unilateral (about 76% of cases) or bilateral (24%), without strong links to age or body size.^[39]^[41]^[40] Clinically, os acromiale is often asymptomatic but can contribute to subacromial impingement syndrome, rotator cuff pathology (associated in up to 50% of cases), and chronic shoulder pain, particularly in active individuals or athletes, due to abnormal motion of the unfused segment. Symptoms typically include superior shoulder pain exacerbated by overhead activities, tenderness over the acromion, reduced range of motion, and weakness, with diagnosis confirmed by radiographs (e.g., axillary view showing a "double-density" sign) or advanced imaging like MRI for soft-tissue assessment. Initial management is conservative, involving 6–12 months of activity modification, physical therapy to strengthen the rotator cuff and deltoid, NSAIDs for pain control, and subacromial corticosteroid injections, which succeed in many cases. For persistent symptomatic instability, surgical intervention focuses on fusion via open or arthroscopic internal fixation (e.g., cannulated screws or tension-band wiring with bone grafting), preserving deltoid function; excision is reserved for small, irreparable pre-acromiale fragments, though it risks deltoid weakness.^[39]^[40]

Wrist and Hand Ossicles

Accessory ossicles in the wrist and hand are supernumerary bones arising from unfused ossification centers or ectopic ossification, commonly identified in the carpal and metacarpal regions. These structures are typically asymptomatic but can mimic fractures on imaging or contribute to clinical symptoms when involved in degenerative changes or trauma.^[42]^[43] A prominent example is the os centrale, a small, trapezoid-shaped accessory bone located dorsally between the scaphoid, capitate, and trapezoid bones near the radioscaphoid joint. It originates as a separate ossification center in the embryo around 6 weeks, which normally fuses with the scaphoid by 8 weeks but persists in some individuals. The prevalence of os centrale is approximately 0.6-1.6% in radiographic studies.^[44]^[43] While often incidental, it may lead to intermittent wrist pain, clicking, or crepitus due to its mobility, and post-traumatic osteonecrosis has been reported, potentially exacerbating arthritis in the adjacent carpal joints. Detection is straightforward on plain radiographs, particularly lateral views, where it appears as a well-corticated ossicle distinct from fracture fragments by its smooth margins.^[44]^[43] The os ulnostyloideum represents a variant at the ulnar styloid, manifesting as a separate ossicle near the ulnar styloid process on the distal ulna's ulnar margin, adjacent to the carpometacarpal joints. This accessory bone results from failure of fusion of the styloid ossification center and has a prevalence of about 1.5% based on wrist radiographs. Clinically, it is usually benign but can be symptomatic if irritated, contributing to ulnar-sided wrist pain or instability, and is frequently mistaken for an acute ulnar styloid fracture in trauma settings due to its location—differentiation relies on imaging showing rounded, sclerotic borders rather than irregular fracture lines. It is readily visible on standard posteroanterior and lateral wrist X-rays.^[43]^[42] On the radial side, the os radiale externum is an accessory ossicle positioned adjacent to the space between the scaphoid tubercle and trapezium, at the distal lateral margin of the scaphoid. It arises from an independent ossification site and occurs in roughly 0.8-2.6% of individuals per radiographic surveys. Though typically asymptomatic, symptomatic cases may involve localized pain or degenerative arthritis at the first carpometacarpal joint, particularly following repetitive stress or injury. Like other wrist ossicles, it is best detected on lateral or oblique X-rays, where its cortical outline helps distinguish it from avulsion fractures.^[43]^[45]^[42] In addition to these carpal variants, sesamoid bones in the hand, such as those embedded in the flexor pollicis brevis tendon at the metacarpophalangeal joint of the thumb, represent normal anatomical features rather than true accessory ossicles and are present in nearly all individuals without clinical consequence.^[42]

Elbow and Forearm Ossicles

Accessory ossicles in the elbow and forearm represent rare supernumerary bones arising from independent ossification centers that fail to fuse with adjacent skeletal elements. These small, typically round or ovoid structures are found near joint articulations, epicondyles, or tendon insertions in the proximal forearm and elbow region, with an overall prevalence of less than 1% in radiographic studies.^[3] They are distinct from sesamoid bones but share similar developmental origins and can occasionally be bilateral.^[46] Prominent examples include the os supratrochleare, located superior to the humeral trochlea within the olecranon or coronoid fossae, where it resides in the joint capsule and may articulate loosely with the olecranon or coronoid process.^[47] Small ossicles near the medial epicondyle (os subepicondylare mediale) or radial head also occur, often embedded in flexor tendons or adjacent to the capitellum.^[48] The patella cubiti, a sesamoid-like ossicle in the triceps tendon, exemplifies posterior variants proximal to the olecranon.^[49] Clinically, these ossicles are usually asymptomatic and discovered incidentally on imaging, but they can mimic avulsion fractures, osteochondritis dissecans, or loose bodies, leading to unnecessary interventions.^[3] In symptomatic cases, they may cause elbow pain, restricted extension, or contribute to epicondylitis by irritating periarticular soft tissues, occasionally requiring excision for relief.^[46] Their low prevalence underscores the need for careful radiographic evaluation to differentiate them from pathology. Accessory ossicles around the elbow and forearm were first described in 19th-century anatomy texts, with systematic classifications emerging in later works by anatomists such as Poirier.^[50] These findings contribute to the broader spectrum of upper extremity variants, briefly relating to distal wrist ossicles in the continuum of forelimb development.

Lower Extremity Accessory Bones

Knee Ossicles

Knee ossicles are small accessory bones located around the knee joint, primarily consisting of the fabella and cyamella, which develop as sesamoid-like structures within tendons. These ossicles are considered normal anatomical variants but can occasionally contribute to clinical issues in the posterolateral knee region. Unlike primary knee bones, they arise from secondary ossification centers and are more prevalent in certain populations, with overall accessory ossicle rates in the lower extremity varying widely based on ethnicity and imaging methods.^[51] The fabella is a small, sesamoid bone typically embedded in the lateral head of the gastrocnemius muscle tendon, positioned posterior to the lateral femoral condyle. It articulates with the posterior aspect of the lateral condyle and is enveloped by the gastrocnemius tendon, aiding in force transmission during knee flexion. Prevalence ranges from 10% to 30% in the general population, with higher rates (up to 87%) observed in Asian cohorts and lower incidences (around 10-20%) in Caucasian groups, where it may be absent entirely in some individuals. The fabella is often bilateral (in about 80% of cases) and its presence increases with age due to progressive ossification. Clinically, it is usually asymptomatic but can lead to posterior knee pain, known as fabella syndrome, through mechanisms such as impingement, chondromalacia, or association with osteoarthritis; in rare instances, it may contribute to cyst formation or require excision for persistent symptoms. On imaging, the fabella is best visualized as a rounded ossicle on lateral knee radiographs, with confirmation via CT or MRI to differentiate it from fractures or loose bodies.^[52]^[53]^[54]^[55] The cyamella, a rarer counterpart, is a sesamoid ossicle located within the popliteus muscle tendon at the posterolateral aspect of the proximal tibiofibular region or distal femur. It develops near the myotendinous junction of the popliteus, which stabilizes the knee during rotation, and is intra-tendinous like the fabella, potentially enhancing tendon efficiency. Its prevalence is low, estimated at 0.57% to 1.8% in ossified form, though it may be underreported due to misidentification as a fabella on imaging; limited data suggest slightly higher occurrence in Asian populations, mirroring trends in other knee sesamoids. Symptomatic cyamellae are exceptional but can cause localized posterior knee pain, tendon irritation, or cyst-like formations, often managed conservatively unless refractory. Radiologically, it appears as a small, oval density on lateral knee views, with MRI providing superior soft-tissue detail to assess tendon involvement and rule out pathology.^[56]^[57]^[58]^[59]

Ankle Ossicles

Ankle ossicles are accessory bones located around the talocrural joint, arising from unfused secondary ossification centers or anomalous development, and they may contribute to localized pain or impingement syndromes when symptomatic.^[2] These structures are typically identified incidentally on imaging, but their clinical relevance increases in cases of trauma or repetitive stress, particularly among athletes.^[2] The os subtibiale is a rare accessory ossicle situated at the posterior aspect of the medial malleolus, inferior to the tip of the tibia, measuring approximately 4-15 mm in size.^[2] It develops from a secondary ossification center that fails to fuse with the medial malleolus and has an estimated prevalence of 0.7-1.2% in the general population.^[2] Clinically, it can cause medial ankle pain, swelling, and redness, often following an inversion injury, and may mimic an avulsion fracture on radiographs.^[60] Initial management is conservative with immobilization or orthotics to restore function, though persistent symptoms after 6 months may necessitate surgical excision.^[60] The os trigonum, a common variant of the lateral posterior process of the talus, forms from a separate ossification center that remains unfused, appearing as a pyramidal or triangular bone posterior to the talus.^[2] Its prevalence varies widely, ranging from 1% to 25% across imaging modalities and populations, with a pooled estimate of 9.0% in meta-analyses of over 36,000 feet.^[61] It is strongly associated with posterior ankle impingement syndrome (PAIS), where repetitive plantarflexion compresses the ossicle against the posterior tibia or calcaneus, leading to deep ankle pain, particularly in athletes such as ballet dancers or soccer players; individuals with PAIS are approximately 16 times more likely to have an os trigonum.^[61] Symptomatic cases often involve subchondral edema, flexor hallucis longus tenosynovitis, or chronic inflammation, and arthroscopic excision is a standard treatment for refractory pain.^[2] The os calcaneus accessorius is an uncommon accessory bone located adjacent to the trochlear eminence or anterior process of the calcaneus, typically measuring about 5 mm and resulting from an unfused apophysis.^[2] It is generally asymptomatic but can be differentiated from avulsion fractures or os subfibulare on computed tomography, where it appears as a distinct ossicle without acute margins.^[2] While prevalence data are limited, related variants like the os calcaneus secundarius occur in 0.6-7% of cases and may contribute to subtle ankle instability if involved in trauma.^[62]

Foot Ossicles

Foot ossicles represent a diverse group of accessory bones primarily located in the midfoot and forefoot regions, arising from unfused secondary ossification centers during skeletal development. These structures are often incidental findings on imaging but can contribute to clinical symptoms such as pain, tendon irritation, or biomechanical alterations when symptomatic. Among the most prevalent are the accessory navicular and os peroneum, with rarer variants including os vesalianum, os supratalare, os calcaneus secundarius, and intermetatarsal ossicles.^[2]^[4] The accessory navicular bone is situated on the medial aspect of the navicular tuberosity, often embedded within or adjacent to the tibialis posterior tendon insertion. It is classified into three types based on morphology and attachment: Type I consists of a small, round ossicle (2-3 mm) embedded in the tendon substance; Type II features a larger, triangular bone connected to the navicular by a synchondrosis; and Type III represents complete fusion, forming a prominent cornuate navicular tuberosity. Prevalence varies by population but generally ranges from 10% to 20%, with higher rates (up to 38%) in East Asian cohorts and lower (around 8%) in North Americans. Symptomatic cases, particularly Type II, can lead to accessory navicular syndrome, characterized by medial foot pain, swelling, and pes planus (flatfoot) due to altered tibialis posterior function and hindfoot valgus.^[63]^[17]^[11]^[64] The os peroneum is a sesamoid ossicle embedded within the peroneus longus tendon, typically near its passage through the cuboid groove. It occurs in 5% to 10% of individuals, though estimates range up to 30% in some radiographic series. This bone enhances tendon leverage but can fracture under tensile stress from inversion injuries or repetitive loading, often associating with peroneus longus tendon tears or chronic degeneration, resulting in lateral foot pain and painful os peroneum syndrome.^[65]^[64]^[66]^[67] Less common foot ossicles include the os vesalianum, located at the base of the fifth metatarsal adjacent to the peroneus brevis insertion, with a rarity that precludes precise prevalence but is noted as infrequent. It typically remains asymptomatic but may cause lateral foot pain mimicking a proximal fifth metatarsal avulsion fracture, potentially linking to peroneal tendonitis through irritation of the peroneus brevis.^[68]^[69]^[70] The os supratalare, positioned superior to the talar head or neck between the ankle and navicular joints, has a low prevalence of approximately 0.5%. It is generally asymptomatic and rarely implicated in pathology.^[71]^[72] The os calcaneus secundarius appears anterior to the calcaneus in the sinus tarsi region, with prevalence estimates from 0.6% to 7%. This triangular ossicle can disrupt subtalar joint mechanics if enlarged or malpositioned, leading to chronic ankle pain or impingement-like symptoms from adjacent hindfoot structures.^[73]^[2]^[71] Intermetatarsal ossicles, such as the os intermetatarseum between the first and second metatarsal bases, are exceptionally rare (less than 0.03%) and may provoke dorsal forefoot pain through mechanical irritation or entrapment.^[74]

Axial and Other Accessory Bones

Vertebral Column Ossicles

Vertebral column ossicles, also known as accessory bones of the spine, represent unfused secondary ossification centers or anomalous bony formations along the axial skeleton, distinct from typical vertebral anatomy. These ossicles can occur in the cervical, thoracic, lumbar, and sacral regions, often identified incidentally on imaging studies such as CT or MRI. While most are asymptomatic, some may contribute to clinical issues through mechanical irritation, vascular compression, or altered biomechanics. Their formation is attributed to developmental variations in ossification, with prevalence varying by location and population demographics.^[75] The ponticulus posticus, a bony bridge forming the arcuate foramen on the posterior arch of the C1 atlas vertebra, is one of the most commonly recognized cervical ossicles. It arises as a variant of the transverse process and posterior arch fusion, potentially enclosing the vertebral artery within the foramen. Prevalence estimates range from 10% to 21% in general populations, with higher rates observed in certain ethnic groups and a slight bilateral symmetry in about 40-50% of cases. This structure can lead to vertebral artery compression during head rotation, potentially causing vertebrobasilar insufficiency symptoms such as dizziness or syncope. Additionally, it has been associated with cervicogenic headaches, where the prevalence of headaches is significantly higher (up to 44%) among individuals with ponticulus posticus compared to those without, possibly due to irritation of surrounding neural structures or altered cervical kinematics. Although direct links to Chiari malformation are less established, some case reports suggest potential contributions to craniovertebral junction anomalies in symptomatic patients.^[76]^[77]^[78] In the lumbar region, intertransverse ossicles, often exemplified by Oppenheimer ossicles, appear as small, rounded bony excrescences near the facet joints or transverse processes, resulting from unfused ossification centers. These are typically located on the superior articular processes of L3-L5 vertebrae and involve incomplete fusion of transverse process elements. Prevalence is approximately 4% (ranging 1-7%), with a higher incidence in males and potential bilaterality. Such ossicles may mimic fractures on imaging but are developmental variants; clinically, they can contribute to low back pain through ligamentous tension or facet joint irritation, occasionally leading to spinal stenosis if associated with flavum ligament buckling. Thoracic accessory ribs, referred to as lumbar ribs when originating from L1, represent elongated transverse processes forming rib-like structures at the thoracolumbar junction. These occur in about 1% of individuals, often bilaterally (65%), and may alter paraspinal muscle attachments or compress neurovascular elements, though symptomatic cases are rare.^[79]^[80]^[81] Sacral variants, such as os sacrum accessorium or accessory sacroiliac ossicles, involve additional bony elements near the sacroiliac joint, often manifesting as accessory articulations between the ilium and sacrum. These arise from separate ossification centers that fail to incorporate into the main sacral body, with prevalence around 13-26% for accessory sacroiliac joints, more common at the S2 level and bilateral in over 50% of affected cases. Anatomically, they extend the joint surface, potentially influencing load distribution across the pelvis. Clinically, these ossicles may correlate with sacroiliac joint dysfunction or lower back pain, particularly in populations with higher mechanical stress, though most remain asymptomatic and are detected via pelvic CT. Overall, vertebral ossicles underscore the spectrum of spinal developmental diversity, with imaging playing a key role in differentiation from pathology.^[82]^[83]^[84]

Episternal Ossicle

The episternal ossicle, also known as the suprasternal ossicle, is a small accessory bone located at the superior margin of the manubrium sterni, typically positioned posterior or superior to this structure near the manubriosternal joint. It is often pyramidal or ovoid in shape, measures 2–15 mm in diameter, and may occur unilaterally or bilaterally, appearing as a well-corticated entity on imaging such as multidetector computed tomography (MDCT). This ossicle represents a normal anatomical variant within the axial skeleton, arising from an independent ossification center distinct from the primary sternal ossification.^[85] The prevalence of episternal ossicles is low, estimated at approximately 2.1% (95% CI: 1.1–3.0%) across global populations based on a meta-analysis of 16 studies involving 7,997 subjects, with regional variations including a higher rate of 3.8% in Asian cohorts. Specific studies report frequencies ranging from 1.5% in a cohort of 800 adults (1.4% in men and 1.7% in women) to 4.1–6.9% in other populations, showing a slight female predominance. Embryologically, it develops from a supernumerary ossification center in the sternal anlage that fails to fuse with the manubrium, unlike the typical sternal ossification where multiple centers merge before birth.^[86]^[87]^[85] Clinically, episternal ossicles are asymptomatic and discovered incidentally on chest radiographs or CT scans, but they can be misinterpreted as pathological entities such as fracture fragments, sequestra, calcified lymph nodes, vascular calcifications, or foreign bodies, necessitating careful radiological evaluation for differentiation. No associated morbidity or functional impairment has been reported, emphasizing their benign nature as a developmental variant.^[87]^[85] Historically, episternal ossicles were first systematically described by Cobb in 1937, though earlier anatomical observations date back to the 19th century, including references by Béclard in 1820 and Breschet in 1838. Subsequent studies in the late 20th century, such as those by Stark et al. in 1987, highlighted their radiographic appearance and prevalence, contributing to greater clinical recognition with advanced imaging modalities.^[88]^[86]

Rare Systemic Accessory Bones

Rare systemic accessory bones are uncommon skeletal variants that arise from aberrant ossification centers and manifest across multiple body regions or in atypical locations, often as components of congenital syndromes rather than isolated anomalies. These ossicles differ from common regional variants by their association with genetic disorders, potentially leading to multisystem involvement and clinical complications such as joint instability or developmental delays. Their prevalence is generally low, estimated at less than 0.5% in the general population, though higher in syndromic contexts.^[75] One prominent example is os odontoideum, a variant of the C2 dens characterized by a separate, corticated ossicle detached from the axis vertebral body, resulting from incomplete fusion during embryogenesis. This condition predisposes individuals to atlantoaxial instability and cervical cord compression, particularly in pediatric cases, and is frequently linked to syndromes such as Morquio syndrome (mucopolysaccharidosis type IVA) and Down syndrome, where ligamentous laxity exacerbates risks. Diagnosis typically involves cervical CT imaging to confirm the ossicle's morphology and assess stability, with whole-body CT recommended in syndromic patients to evaluate for concurrent anomalies. Surgical fusion may be indicated for symptomatic instability.^[89]^[90]^[91] In cleidocranial dysplasia (CCD), a rare autosomal dominant disorder caused by RUNX2 gene mutations, multiple accessory ossicles occur due to defective intramembranous ossification, affecting the cranium, pelvis, and extremities. Skull sutures often contain numerous Wormian bones—small, irregular accessory ossicles embedded within the lambdoid or sagittal sutures—contributing to delayed fontanelle closure and cranial deformities. Additional systemic manifestations include accessory bones in the hands and feet, alongside clavicular hypoplasia, highlighting the disorder's broad skeletal impact. CCD has a prevalence of approximately 1 in 1,000,000, with diagnosis confirmed via genetic testing and radiographic surveys, including whole-body imaging to map ossific defects. Management focuses on orthopedic interventions for associated instability.^[92]^[93] Accessory metacarpals in polydactyly syndromes represent another systemic rarity, where supernumerary carpal or metacarpal ossicles accompany extra digits, often in genetic conditions like Ellis-van Creveld syndrome or Bardet-Biedl syndrome. These ossicles arise from duplicated ossification centers and can lead to hand deformities, reduced function, and syndromic features such as retinal dystrophy or renal anomalies. Prevalence varies by syndrome but remains under 0.5% overall, with central or postaxial polydactyly types showing proximal accessory metacarpals in up to 20% of cases. Clinical evaluation includes hand radiographs and genetic analysis, with whole-body CT useful for multisystem assessment; surgical reconstruction addresses functional impairments.^[94]^[95]

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Accessory ossicles are inconstant, independent, and considered well formed bones, not arising from fractures or other diseases.
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Accessory ossicles | Radiology Reference Article | Radiopaedia.org
Jan 6, 2025 · Accessory ossicles are secondary ossification centers that remain separate from the adjacent bone. They are usually round or ovoid in shape.Ossicles of the foot · Wrist · Cyamella
[7]
Accessory Ossicles of the Foot and Ankle: Disorders and a Review ...
Nov 26, 2017 · The incidence of the accessory navicular bone has been reported to be 4%-21% [9-10,15]. Three types of accessory navicular bones have been ...Missing: body | Show results with:body
[8]
Sesamoids and accessory ossicles of the foot: anatomical variability ...
In contrast, accessory ossicles are supernumerary bones that commonly derive from unfused primary or secondary ossification centres [1]. They are thought to be ...Missing: definition | Show results with:definition
[9]
6: Normal Variants and Anomalies - Musculoskeletal Key
Aug 22, 2016 · Supernumerary bones include duplication of phalanges, metatarsals, and tarsal bones. BOX 6-1 Expression of Variants in the Foot. Variations ...
[10]
Embryology, Bone Ossification - StatPearls - NCBI Bookshelf - NIH
Bone ossification, or osteogenesis, is the process of bone formation. This process begins between the sixth and seventh weeks of embryonic development.
[11]
Accessory Ossification Centers - Radiology Key
Feb 7, 2017 · Accessory ossification centers are nontraumatic occurrences; the mechanism of injury is failure to fuse during development.
[12]
The prevalence and anatomy of accessory navicular bone - NIH
Aug 13, 2024 · There have been over 40 descriptions of the common developmental variants of the accessory ossicles of the feet.
[13]
Mechanical regulation of musculoskeletal system development
Dec 1, 2017 · Bone morphology is regulated by mechanical forces at different levels, as demonstrated by the various developmental and functional aberrations ...Missing: accessory | Show results with:accessory
[14]
Structure of Bone Tissue - SEER Training Modules
There are two types of bone tissue: compact and spongy. The names imply that the two types differ in density, or how tightly the tissue is packed together.
[15]
https://www.sciencedirect.com/science/article/abs/pii/S1619998723001198
[16]
Accessory bones at the foot and ankle: A comprehensive review
Calcaneus secundarius. The calcaneus secundarius, also called secondary os calcis, is an accessory ossicle of the anterior facet of the calcaneus [52].
[17]
The prevalence and anatomy of accessory navicular bone: a meta ...
Aug 13, 2024 · The overall prevalence of accessory navicular is believed to fall within the 4–21% range [18, 19, 38, 47, 57], making it one of the most common ...
[18]
The prevalence and anatomy of accessory navicular bone - PubMed
Aug 13, 2024 · Accessory navicular was most prevalent in the East Asian population (38.4%) and least prevalent in North Americans (8.0%). No significant ...
[19]
Anatomical variation in the ankle and foot: from incidental finding to ...
Jul 31, 2019 · Most accessory ossicles and sesamoids will represent an incidental finding on radiographs. Accessory muscles can occasionally represent an ...
[20]
The Prevalence of Accessory Ossicles, Sesamoid Bones, and ...
Jan 18, 2022 · We detected accessory bone in 26%, sesamoid bone in 8%, and biphalangeal toe in 43% of all radiographic scans. The most common accessory bones ...<|separator|>
[21]
Assessing the Outcomes Associated with Accessory Navicular Bone ...
Jul 1, 2022 · The Kidner procedure postoperative outcomes were reported as 58% excellent, 27% moderate, and 13% poor (Table 5). Of the papers that reported ...
[22]
Developmental Talocalcaneal Coalitions and Associated Conditions
One proposed etiology for tarsal coalitions has been the incorporation of accessory ossicles of the foot; however, this mechanism fails to explain why ...
[23]
[PDF] Accessory navicular surgery - Royal Berkshire Hospital
Accessory navicular surgery, April 2025. 2. What are the success rates and risks? The surgery has a success rate of about 90% (9 out of every 10) in taking ...
[24]
[PDF] Surgical Treatment of Symptomatic Accessory Navicular in Children ...
Isolated excision of the AN through a PT tendon split was successful in 13 (93%) of 14 feet; 1 of the 14 required reopera- tion because of a painful scar. A ...<|separator|>
[25]
SURGICAL OUTCOMES OF ACCESSORY NAVICULAR IN ... - NIH
Jul 14, 2021 · Surgery eliminated pain in 76% of patients and allowed 94% of patients to return to sport. Residual pain in 4 patients was correlated with a pre ...Missing: ossicles | Show results with:ossicles
[26]
Incidence and Medicolegal Significance of Wormian Bones in ...
Wormian bones are small, irregular bones near skull sutures. In this study, 35.3% of skulls had them, with 23.8% in males and 11.5% in females.Missing: definition prevalence sources
[27]
The Tomographic Study and the Phenotype of Wormian Bones - MDPI
Feb 24, 2023 · The traditional definition of wormian bones is small bones that are often found within the sutures and fontanelles of the skull. Some instances ...Missing: prevalence sources
[28]
Wormian Bones: Prevalence, Topography, and Implications - PubMed
Wormian bones are asymmetrical, shapeless bones in cranial sutures, found in 380 sides of 190 skulls, mainly in lambdoid and sagittal sutures.Missing: definition scholarly sources
[29]
(PDF) ANTHROPOLOGICAL REVIEW Prevalence of wormian bones ...
Jan 17, 2023 · The aim of this paper is to perform a critical review of research studies on the presence of Wormian bones in populations worldwide, with a ...
[30]
Wormian bones in osteogenesis imperfecta: Correlation to ... - PubMed
SNWB were observed in 35% of patients with OI type I, in 96% of patients with OI type III and 78% of patients with OI type IV.
[31]
The presence of Wormian bones increases the fracture resistance of ...
Apr 16, 2021 · The presence of Wormian bones, which are confined to the calvaria, increase the compliance of the bone and reduce the likelihood of skull fracture.
[32]
Inca - interparietal bones in neurocranium of human skulls in central ...
Inca ossicles are accessory bones found in human skulls as interparital bones. Gross incidence of Inca ossicles was 1.315 %. A very high incidence (27.71 %) of ...Missing: prevalence relevance
[33]
Os incae: variation in frequency in major human population groups
The New World populations have generally high frequencies of the Inca bone, whereas lower frequencies occur in northeast Asians and Australians.Missing: prevalence Native
[34]
[PDF] Interparietal and pre-interparietal bones in the population of south ...
The squamous occipital bone develops from two parts: a membranous interparietal part above and cartilaginous supra-occipital part below the high- est nuchal ...Missing: prevalence | Show results with:prevalence
[35]
Os Incae: Variation in frequency in major human population groups
Aug 7, 2025 · Journal of Anatomy 198(Pt 2):137-52 ... Coexistence of Complete Metopic Suture and Inca Bone in Thai Skulls: Incidence, Morphology and Clinical ...
[36]
[PDF] Interparietal (Inca) bone: a case report - Pulsus Group
May 6, 2011 · International Journal of Anatomical Variations (2011) 4: 90–92 ... as the interparietal or Inca bone. The occurrence of Inca variable is ...Missing: prevalence | Show results with:prevalence
[37]
[PDF] Interparietal Bone Variations in Accordance with their Ossification ...
According to the available literature, the interparietal segment is ossified from 2 to 3 pairs of ossification centres and each of these centres has 2 nuclei.
[38]
Interparietal Bone (Os Incae) in Craniosynostosis | Request PDF
Aug 6, 2025 · The true incidence of an interparietal bone in patients with craniosynostosis or craniofacial anomalies ... Occasionally there are multiple ...Missing: asymptomatic | Show results with:asymptomatic
[39]
[Interparietal bone in forensic practice: case report] - PubMed
The interparietal bone could be interpreted wrongly as belonging to the fractured occipital bone ... Parietal Bone / abnormalities*; Parietal Bone / injuries ...
[40]
Os Acromiale: Reviews and Current Perspectives - PMC - NIH
The prevalence of os acromiale is 1% to 15%, and is quite common in the African American population. Os acromiale in adults is easily diagnosed by symptoms and ...
[41]
Os acromiale: a review of its incidence, pathophysiology, and ... - NIH
Aug 9, 2019 · It is present in approximately 8% of individuals, and whilst the majority of these individuals are unaffected it can cause significant pain and ...
[42]
Os acromiale: prevalence and associated patient-related factors—a ...
The purpose of this study was to assess the prevalence, anatomy, and associations of os acromiale in a general adult population.
[43]
Accessory ossicles of the wrist | Radiology Reference Article | Radiopaedia.org
### Summary of Accessory Ossicles of the Wrist
[44]
The Incidence of Accessory Ossicles of the Wrist: A Radiographic ...
Lawson stated that the incidence of os styloideum in the normal wrist is in the range of 1.3 to 3%. In this study, the incidence of os styloideum was found to ...
[45]
Os centrale carpi | Radiology Reference Article | Radiopaedia.org
Jul 25, 2017 · Epidemiology. It has an incidence of 0.3-1.6% 2. Development. It is thought to represent a separate ossification center that is ...Missing: prevalence | Show results with:prevalence
[46]
Accessory and Sesamoid Bones in the Body: A study on their Size ...
Jan 31, 2024 · In the hand, the most common accessory ossicles were os triangulare (6.08%), os radiale externum (2.60%) and os centrale (1.73%). Accessory ...
[47]
Osseous variability around the elbow joint - Sage Journals
There are many osseous variants that occur around the elbow joint such as supracondylar process, supratrochlear foramen, accessory ossicles, and others.<|control11|><|separator|>
[48]
Accessory ossicles of the elbow | Radiology Reference Article
Oct 29, 2021 · Accessory ossicles of the elbow are rare anatomical variants, also called supernumerary bones, that may be misdiagnosed as fractures.Missing: forearm ulnare externum
[49]
Os Subepicondylare Mediale in the Elbow: A Radiographic Case ...
Jun 1, 2024 · Sesamoid and accessory bones are small, oval-shaped structures that develop within tendons that pass over bony prominences.Missing: externum | Show results with:externum<|control11|><|separator|>
[50]
The elbow - Radiology Key
Jan 10, 2016 · Two accessory ossicles are known to occur about the elbow joint: the os supratrochleare and the patella cubiti. The os supratrochleare is a ...Missing: externum | Show results with:externum
[51]
Accessory ossicles in the elbow - Acta Orthopaedica
Jan 1, 1987 · Accessory ossicles in the elbow are often diagnosed as osteochondritis dissecans or chondromatosis, but no terminologic agreements seem to exist ...Missing: forearm ulnare externum
[52]
Fabella prevalence rate increases over 150 years, and rates of other ...
Apr 17, 2019 · The fabella is a sesamoid bone located behind the lateral femoral condyle. It is common in non‐human mammals, but the prevalence rates in humans vary from 3 to ...
[53]
A Comprehensive Review of the Fabella Bone - PMC - NIH
Jun 5, 2018 · It is found in approximately 10% to 30% of the population and it occurs bilaterally in approximately 80% of cases [1,6,7]. In the Asian ...
[54]
Fabella | Radiology Reference Article | Radiopaedia.org
The fabella (plural fabellae 5) is an accessory ossicle that is almost always found in the lateral head of the gastrocnemius although rarely it can occur in ...
[55]
Human biological variation in sesamoid bone prevalence: the ...
Oct 17, 2019 · Globally, fabellae are understood to be more common in Asian populations, with prevalence rates reaching 87% in Japan (Zeng et al. 2012), than ...
[56]
Fabellar prevalence, degeneration and association with knee ...
Sep 10, 2019 · The fabella is usually a benign structure; however, in rare cases, it involves disorders, such as chondromalacia, osteoarthritis, dislocation ...
[57]
Cyamella (a popliteal sesamoid bone) prevalence - PubMed
May 4, 2021 · Only two studies have investigated cyamella presence/absence in humans, putting ossified prevalence rates at 0.57%-1.8%. We aim to (a) determine ...
[58]
Cyamella | Radiology Reference Article - Radiopaedia.org
Jul 16, 2025 · Because of its rarity compared to the more common fabella, most “cyamella” seen on imaging are a misidentified fabella, even in the literature.
[59]
Coexistence of symptomatic cyamella and multiple fabellae - NIH
... bone of the knee.[1-4] The prevalence of ossified cyamella is reported to be between 0.57 and 1.8%.[3] A symptomatic cyamella is very rare and described in ...
[60]
The cyamella, a lost sesamoid: Normal variant or posterolateral ...
Mar 20, 2014 · Cyamella, an accessory sesamoid ossicle of the popliteus in the region of the proximal myotendinous junction, is an extremely unusual finding.
[61]
[Os subtibiale: That odd ankle pain] - PubMed
Nov 25, 2020 · Os subtibiale is a low prevalence accessory bone of the ankle. This bone is located in the posterior colliculus of the tibial medial malleolus, both in ...
[62]
Prevalence and clinical aspects of os trigonum: a meta-analysis - PubMed
### Summary of Prevalence, Clinical Aspects, and Association with Impingement of Os Trigonum
[63]
Anatomical variation in the ankle and foot: from incidental finding to ...
Jul 31, 2019 · The os calcaneus secundarius is a rare accessory ossicle of the foot, estimated to have a prevalence between 0.6 and 7% [1, 3]. It can be round ...
[64]
Prevalence and classification of accessory navicular bone - NIH
The incidence of accessory ossicles in the foot and ankle varies between 2% and 25% among the general population, with an epidemiological rate of 21% in a study ...
[65]
Prevalence of Accessory Bones and Tarsal Coalitions Based ... - NIH
The prevalence of accessory bones in adults was the highest with 34% for the accessory navicular, 5.8% for the os trigonum, 3.9% for the os peroneum, and 1.7% ...Missing: upper parietal
[66]
Painful Os Peroneum Syndrome: Underdiagnosed Condition ... - NIH
Jun 23, 2016 · Os peroneum is identified in 4.7–30% of normal feet [1] and is bipartite in approximately 30% of cases and unilateral in 40%. Its fully ossified ...2. Case Report · Figure 1 · 3. DiscussionMissing: accessorius | Show results with:accessorius
[67]
Os Peroneum - StatPearls - NCBI Bookshelf
[9][10] Fractures of the os peroneum may be associated with peroneus longus tendon rupture in the acute setting or may be associated with chronic degeneration ...Etiology · Epidemiology · Evaluation · Differential Diagnosis
[68]
Peroneal Tendon Pathology Associated with the Presence of an Os ...
A painful os peroneum syndrome is a common cause of plantar, lateral foot pain, which can be caused by a spectrum of conditions such as os peroneum fracture, ...
[69]
The Prevalence and the Clinical Importance of os vesalianum pedis
Os vesalianum pedis (OVP) is a rare accessory bone of the foot located at the base of the fifth metatarsal bone. It is usually asymptomatic and incidentally ...
[70]
A Case Report on Painful Os Vesalianum Pedis Masquerading ... - NIH
It is usually asymptomatic but can mimic an avulsion fracture of proximal 5th metatarsal and is an infrequent cause of lateral foot pain.Missing: relevance | Show results with:relevance
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Os Vesalianum Pedis in a Young Adult: A Case Report and ... - NIH
May 7, 2021 · Os vesalianum pedis is a rare accessory foot ossicle. It is usually asymptomatic, however, it can be an infrequent cause of lateral foot pain.Missing: relevance | Show results with:relevance
[72]
Accessory Ossicles in the Region of the Foot and Ankle - NIH
Oct 29, 2021 · The os supratalare, also known as talus secundarius, is typically located superior to the head or neck of talus between the ankle and ...
[73]
The Prevalence of Accessory Ossicles, Sesamoid Bones, and ... - NIH
Accessory ossicles, sesamoid bones, and biphalangism of toes are the most common developmental variations of the foot.Missing: definition | Show results with:definition
[74]
Calcaneus secundarius – a relevant differential diagnosis in ankle ...
Jun 2, 2015 · With a prevalence ranging from 0.14% up to 7% the CS is one of the more infrequently found accessory bones of the foot, which though should not ...
[75]
Os intermetatarseum – A case report - PMC - PubMed Central
Dorsal foot pain can be caused by a symptomatic Os intermetatarseum – an accessory ossicle found between the bases of first and second metatarsals and the ...
[76]
implications for spinal pathophysiology and differential diagnosis
Mar 6, 2025 · Accessory ossicles are aberrant ossification centers that arise due to variations in normal ossification pathways during fetal development [17].
[77]
Incidence of ponticulus posterior of the atlas in migraine ... - PubMed
An 18% prevalence of ponticulus posticus was found. ... The mechanism for this remains obscure but may be related to ischemic compression of the vertebral artery ...
[78]
Does ponticulus posticus affect vertebral artery diameter - PubMed
Among this group, PP was detected in 288 individuals, resulting in a total prevalence of 21.1%. ... Ponticulus posticus; Vertebral artery diameter. © 2024 ...
[79]
(PDF) Prevalence and characteristics of ponticulus posticus and its ...
Aug 9, 2025 · Among patients with the anomaly, 43.8% had cervicogenic headache and 9.4% had migraine. There was a significant association between the presence ...<|control11|><|separator|>
[80]
Oppenheimer ossicle | Radiology Reference Article - Radiopaedia.org
Apr 2, 2025 · Oppenheimer ossicles are accessory ossicles associated with the facet joints and are found in ~4% (range 1-7%) of lumbar spines.
[81]
Oppenheimer's accessory ossicle and clinical significance
The failure of secondary ossification centers at the inferior articular processes of the lumbal vertebrae causes OO with a 0.5–7% prevalence. CT, MDCT, or SPECT ...
[82]
Oppenheimer's ossicles in the lumbar spine-a rare cause of lumbar ...
Rarely as in the reported patient the ossicles can cause lumbar canal stenosis due to buckling of the ligamentum flavum which encroaches into the epidural space ...1. Introduction · Fig. 1 · Fig. 2Missing: intertransverse | Show results with:intertransverse
[83]
Prevalence of accessory sacroiliac joint anatomy and associated ...
Jan 16, 2023 · The overall prevalence of bilateral ASIJ anatomy given any ASIJ anatomy was 53.3%. Of those patients with ASIJs at S1 (n=56), 25 (44.6%) had ...Missing: os | Show results with:os
[84]
The accessory sacroiliac joint: a common anatomic variant | AJR
We identified the accessory sacroiliac joint on 13 (13%) of 100 CT scans of the pelvis and in nine (16%) of 56 dried skeletons. The joint is situated ...Missing: ossicles | Show results with:ossicles
[85]
Lumbar rib | Radiology Reference Article | Radiopaedia.org
Sep 16, 2025 · Lumbar (or 13 th ) ribs are a rare anatomical variant and represent transitional vertebrae at the thoracolumbar junction with a prevalence of ~1%.
[86]
MDCT evaluation of sternal variations: Pictorial essay - PMC
Suprasternal or episternal ossicle or suprasternal bone. Suprasternal or episternal ossicle is a small accessory ossicle at the superior margin of manubrium ...Missing: historical | Show results with:historical
[87]
Anatomical study and meta-analysis of the episternal ossicles
Jan 9, 2024 · An overall EO prevalence was 2.1% (95% CI 1.1-3.0%, I2 = 93.75%). Subgroup analyses by continent and diagnostic methods were carried out. Asia ...<|control11|><|separator|>
[88]
Episternal ossicles - PubMed
Episternal ossicles represent a normal variant and should be distinguished from fracture fragments, sequestra, foreign bodies, calcified lymph nodes, or ...Missing: Gruber 1875
[89]
A Collage of Musculoskeletal Disorders - Consultant360
Episternal ossicles are a normal variant of the sternum. First described by Cobb in 1937,1 episternal ossicles have received scant recognition. The development ...
[90]
Os Odontoideum - StatPearls - NCBI Bookshelf - NIH
Os odontoideum is a rare cervical anomaly stemming from a developmental failure in the odontoid process. This condition has an uncertain estimated prevalence, ...Missing: accessory | Show results with:accessory
[91]
Os odontoideum | Radiology Reference Article | Radiopaedia.org
May 15, 2025 · Os odontoideum (plural: ossa odontoidea) is an anatomic variant of the odontoid process of C2 and needs to be differentiated from persistent ossiculum ...Os odontoideum · Persistent ossiculum terminale · Variant anatomy of the...
[92]
Os Odontoideum Diagnosis & Treatment - NYC
This is the joint that allows the head to turn, rotate, and nod. One special feature of this joint is a peg of bone, about the size of the tip of a pinky finger ...Missing: accessory | Show results with:accessory<|separator|>
[93]
Cleidocranial dysplasia - Genetics - MedlinePlus
Aug 1, 2017 · Some individuals with cleidocranial dysplasia have extra pieces of bone called Wormian bones within the sutures. Affected individuals are ...Missing: accessory | Show results with:accessory
[94]
Cleidocranial Dysplasia Spectrum Disorder - GeneReviews - NCBI
Jan 3, 2006 · CCD spectrum disorder affects most prominently those bones derived from intramembranous ossification, such as the cranium and the clavicles, ...
[95]
Clinical Genetics of Polydactyly: An Updated Review - Frontiers
Nov 5, 2018 · The metacarpal of the accessory digit shows distal epiphysis, due to such phenotypes PPD type 3 is separated from PPD type 2 or TPT (Swanson ...
[96]
Polydactyly: Clinical and molecular manifestations - PubMed Central
Jan 18, 2023 · It frequently presents with polydactyly with six digits and six metacarpals. It is inherited with an autosomal dominant trait.