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GC

Gender critical (GC) is a feminist that asserts —defined as an immutable characteristic determined by reproductive anatomy and gametes—is the primary axis of women's under and the basis for sex-based , categories, and protections, while rejecting the subordination of these to subjective claims. GC advocates maintain that women are adult human s and that conflating with erodes single-sex spaces, sports, and services essential for female safety, fairness, and autonomy, drawing on evidence of physical dimorphism and patterns of male . Emerging from radical feminist traditions of the and that critiqued as a tool of male dominance, the contemporary GC movement gained traction in the 2010s amid legal pushes for , such as proposed reforms to the 's Gender Recognition Act, which GC groups argued would undermine women's protections by allowing males to access female-only domains without safeguards. Notable figures include philosopher , who resigned from her university post amid backlash for GC views, and activist , whose writings emphasize sex-based analysis of . The position has faced intense controversy, including professional repercussions and labels of bigotry from institutions, yet secured legal victories like the 2021 ruling that GC beliefs qualify as protected philosophical convictions under equality law.

Computing

Garbage collection

Garbage collection (GC) is an automatic memory management mechanism in programming languages that identifies and reclaims memory occupied by objects no longer reachable from the program's roots, such as stack variables or global references, thereby preventing memory leaks and reducing manual deallocation errors. This process contrasts with manual memory management in languages like C, where programmers explicitly allocate and free memory using functions such as malloc and free. GC was first implemented by John McCarthy in 1959 as part of the Lisp programming language to handle dynamic memory allocation in a recursive environment. GC operates in two primary phases: marking, where reachable objects are traced from , and sweeping or copying, where unmarked objects are deallocated or relocated to compact the . Common algorithms include , which tracks the number of references to each object and frees it when the count reaches zero; mark-and-sweep, which scans for unreachable objects after marking live ones; and generational collection, which divides the into generations based on object age to optimize for short-lived objects. Advanced variants, such as concurrent or incremental GC, aim to minimize application pauses by performing collection in parallel with execution. Languages employing GC include , which uses a generational collector in the JVM; C#, with the .NET CLR's managed heap; , combining with ; Go, featuring a tri-color mark-and-sweep collector; and JavaScript engines like V8, which apply generational and incremental techniques. Advantages of GC include increased developer productivity by automating deallocation, elimination of common bugs like dangling pointers and double frees, and potential memory compaction to reduce fragmentation. However, it introduces overhead from collection cycles, unpredictable pause times that can affect systems, and challenges in handling circular references without additional mechanisms. Modern implementations mitigate these through low-pause collectors, as in Java's ZGC introduced in JDK 11 for sub-millisecond latencies on large heaps.

Science

Gas chromatography

Gas chromatography (GC) is an instrumental analytical technique for separating and detecting volatile and semi-volatile compounds in a by vaporizing the sample and passing it through a column with a carrier gas. The separation occurs due to differences in the analytes' partitioning coefficients between a mobile gaseous phase and a stationary phase, typically a thin liquid film adsorbed onto a solid support or coated on capillary walls. This method provides high resolution and sensitivity, enabling quantitative and qualitative analysis based on retention times and peak areas./Instrumentation_and_Analysis/Chromatography/Gas_Chromatography) The technique was first described in 1952 by British chemists Archer J. P. Martin and Anthony T. James, building on Martin's earlier work in that earned him the 1952 shared with Richard L. M. Synge. Commercial instruments emerged shortly after, with early adoption in analysis for separation. Advancements in the 1970s, including fused-silica capillary columns introduced by Marcel Golay, improved efficiency and reduced analysis times from hours to minutes. By the 1980s, coupling with (GC-MS) became routine, enhancing identification capabilities through spectral matching against libraries containing millions of compounds. In operation, a sample is injected into a heated port where it vaporizes and mixes with an inert carrier gas, such as or , which propels it through the column housed in a temperature-controlled . Analytes interact variably with the phase—via adsorption, , or size exclusion—causing slower-moving compounds to elute later, producing a chromatogram of peaks whose positions (retention time) and intensities reflect and concentration. Column types include packed columns, filled with coated solid particles for higher sample capacity but lower , and open tubular columns, which dominate modern use for their superior plate counts exceeding 100,000 theoretical plates per meter. Temperature programming, starting low and ramping up, optimizes separation of compounds with wide ranges./Instrumentation_and_Analysis/Chromatography/Gas_Chromatography) Key components include the (split/splitless for varying sample sizes), column (polar or non-polar phases like ), detector, and system. Detectors quantify eluted analytes; the (FID) is most common, burning effluents in hydrogen flame to produce ions proportional to carbon content, offering picogram sensitivity for organics but destructive to the sample. Thermal conductivity detectors (TCD) measure universal changes in gas thermal properties non-destructively, suitable for permanent gases with lower sensitivity. detectors (ECD) excel for halogenated compounds via beta-ionization, achieving femtogram detection limits. Mass spectrometric detectors in GC-MS provide structural elucidation by ionizing and fragmenting molecules, with electron impact at 70 generating characteristic spectra for searches. Applications span for pollutants like volatile organic compounds (VOCs) at parts-per-billion levels, pharmaceutical for residual solvents per ICH Q3C guidelines, for residues, and forensics for and profiling. In , GC determines composition, aiding via standards like ASTM D4815. Limitations include unsuitability for non-volatiles or thermally labile compounds, requiring derivatization, and potential matrix interferences necessitating sample preparation like . Despite these, GC's speed (analyses in 5-60 minutes) and reproducibility (relative standard deviations <1% for peaks) make it indispensable in over 50% of routine organic analyses./Instrumentation_and_Analysis/Chromatography/Gas_Chromatography)

Glucocorticoid

Glucocorticoids are a class of hormones primarily synthesized in the of the , with serving as the principal in humans. These hormones are essential for maintaining , particularly during , by modulating metabolic processes, immune responses, and cardiovascular function. Their production is regulated by the axis, where (CRH) from the stimulates (ACTH) release from the pituitary, which in turn prompts adrenal secretion. Circulating levels exhibit a diurnal , peaking in the early morning and at night, with acute elevations in response to stressors such as or . Physiologically, glucocorticoids exert catabolic effects to mobilize energy reserves, promoting in the liver by upregulating enzymes such as and glucose-6-phosphatase, while inhibiting peripheral glucose uptake in muscle and . They antagonize insulin action, elevate blood glucose levels to ensure fuel availability for the during , and stimulate and protein breakdown in to provide substrates for hepatic glucose production. In the immune system, suppress by binding intracellular glucocorticoid receptors (GR), which translocate to the nucleus to inhibit pro-inflammatory transcription factors like and AP-1, thereby reducing production (e.g., IL-1, IL-6, TNF-α) and promoting in lymphocytes and . This immunosuppressive action prevents excessive immune activation but can impair clearance if prolonged. The mechanism of glucocorticoid action primarily involves genomic effects: lipophilic diffuse across cell , bind cytoplasmic , form a complex that dissociates heat-shock proteins, and translocates to the to modulate , either through direct DNA binding or transrepression of other factors. Non-genomic effects, such as rapid modulation of proteins or second messengers, also occur but contribute less to long-term physiological impacts. Synthetic glucocorticoids, analogs of with enhanced potency or duration (e.g., , dexamethasone, ), are widely used therapeutically for their and immunosuppressive properties in conditions like , exacerbations, rejection, and autoimmune diseases. These agents mimic endogenous actions but often at higher doses, leading to risks such as iatrogenic adrenal suppression upon abrupt withdrawal due to axis inhibition. Pathological dysregulation of manifests in disorders like , characterized by chronic excess (often from pituitary adenomas or exogenous ) causing central obesity, , , and via sustained activation. Conversely, results from , leading to glucocorticoid deficiency with symptoms including , , and , necessitating lifelong replacement . Glucocorticoid resistance syndrome, a rare genetic condition from NR3C1 mutations impairing GR function, presents with elevated levels without typical hypercortisolism stigmata, sometimes compensated by increased mineralocorticoids or androgens. Long-term synthetic glucocorticoid use correlates with adverse effects including (via inhibition), , and increased infection susceptibility, underscoring the need for dose minimization and monitoring.

Places

Gold Coast

The is a coastal city located in southeastern , , approximately 66 kilometres south of . It serves as the administrative centre of the local government area, which spans 1,402 square kilometres and encompasses 57 kilometres of coastline along the . As 's sixth-largest city, it had an estimated resident population of 681,389 as of June 2024. The region features a subtropical climate with average annual temperatures ranging from 15°C in winter to 28°C in summer, supporting year-round outdoor activities. Its geography includes golden sand beaches, hinterland rainforests, and urban high-rises concentrated in areas like Surfers Paradise. Originally inhabited by the Kombumerri people of the group, European settlement began in the with and plantations, transitioning to a recreational destination in the early . Rapid post-World War II development, driven by promotion, led to suburban expansion and growth, including the 1958 amalgamation of coastal townships into the . The economy is dominated by , which attracts approximately 13 million visitors annually and generated $8.1 billion in spending for the year ending December 2024. Key sectors include , , , and , with diversification into services and . Theme parks such as and Sea World, along with events like the Gold Coast Marathon, bolster visitor numbers, comprising about 4.93 million tourists in 2024, predominantly domestic. The city's GDP contributions reflect its role as a major non-capital economic hub, supported by international arrivals via .

Gran Canaria

is the third-largest island in the archipelago, situated in the about 150 kilometers off the northwestern coast of and politically part of Spain's autonomous community of the . The island spans 1,560 square kilometers of primarily volcanic terrain, characterized by a central mountainous core rising to 1,949 meters at Pico de las Nieves, steep ravines, and diverse landscapes ranging from pine forests to arid dunes. Its 236 kilometers of coastline include sandy beaches and dramatic cliffs, contributing to its varied microclimates. Human settlement began around 500 BCE with populations from , who developed a society reliant on , , and mummification practices; genetic and archaeological evidence confirms their North African origins and isolation until European contact. The island's conquest by the Crown of occurred between 1478 and 1483, led by figures such as Juan Rejón and completed by Pedro de Vera, involving military campaigns against indigenous resistance centered in Gáldar and , resulting in the subjugation and displacement of native Canarians. Colonization introduced , European settlers, and the founding of Las Palmas de Gran Canaria in 1478 as the island's administrative hub. As of 2024, Gran Canaria's population stands at approximately 870,000, densely concentrated in urban areas like Las Palmas de Gran Canaria, which hosts over 380,000 residents. The economy centers on tourism, which has driven growth since the first charter flights in 1957 and now accounts for up to 80% of regional gross income through beach resorts, hiking, and water sports, bolstered by the island's subtropical climate featuring average temperatures of 18–24°C year-round and minimal rainfall in coastal zones. Agriculture persists in fertile northern valleys, exporting bananas, tomatoes, and potatoes to Europe and beyond, while ports like Las Palmas facilitate transatlantic trade.

Transportation

General classification (cycling)

The , often abbreviated as , constitutes the primary overall ranking in multi-stage professional races, aggregating each rider's cumulative elapsed time across all stages to determine the leader with the fastest total time. This classification emphasizes and consistency, distinguishing it from secondary competitions like points or mountains standings, which reward sprinting prowess or climbing ability, respectively. In Grand Tours such as the , , and , the GC winner receives the highest prestige and substantial prize money, often exceeding €500,000 in the as of 2024. Calculation of GC positions involves summing individual stage finishing times, adjusted by time bonuses—typically 10, 6, and 4 seconds awarded to the top three finishers in mass-start stages or at intermediate sprints—and deductions for penalties incurred due to rule violations like behind vehicles, which can add 20 seconds or more per infraction under UCI regulations. If riders finish in the same group at the stage end, they receive identical times to preserve dynamics, but solo breakaways or time trials yield precise individual timings. The UCI mandates that stage race organizers define bonus structures in advance, ensuring transparency, though specifics vary; for instance, the allocated bonuses only on select flat stages to balance climber advantages in mountainous terrain. Historically, the GC originated with the inaugural in 1903, where claimed victory by over two hours in the points-based precursor that evolved into modern time trials by 1920. The distinctive yellow jersey for the GC leader debuted in the , inspired by the race's newspaper sponsor L'Auto's yellow pages, and has since become iconic, with similar colored leader jerseys adopted in other Grand Tours (pink for , red for ). UCI oversight standardized GC protocols across WorldTour events starting in 2005, mandating electronic timing chips for accuracy and prohibiting team-based time credits beyond the first three riders' aggregated times for team classification purposes. GC contention shapes race strategies, with teams protecting "GC riders"—specialists like , who won the by 6 minutes 17 seconds—through domestique support to neutralize attacks and conserve energy on non-critical stages. Unlike one-day classics, where raw power suffices, GC success demands tactical acumen in time trials (often 20-60 km individual efforts) and mountain stages, where gradients exceeding 10% can create time gaps of minutes. Doping scandals, including Lance Armstrong's stripped 1999-2005 victories, have prompted stricter UCI anti-doping measures, yet empirical data from biological passports since 2008 shows sustained high-level performances, with average GC winning margins tightening to under 2 minutes in recent editions due to advanced training and nutrition.

Organizations

General Conference (Seventh-day Adventist Church)

The General Conference of Seventh-day Adventists serves as the highest administrative authority and coordinating body for the global Seventh-day Adventist Church, encompassing over 22 million members across approximately 200 countries as of recent reports. Headquartered at 12501 Old Columbia Pike in Silver Spring, Maryland, United States, it oversees the church's administrative divisions, departments, and worldwide mission activities while maintaining a representative form of governance. The organization emphasizes biblical principles, health reform, education, and evangelism, reflecting the church's foundational beliefs derived from the teachings of early leaders like Ellen G. White. Established on May 20, 1863, in , the General Conference emerged from the need to unify scattered Sabbath-keeping Adventist groups into a structured amid rapid growth following the 1844 movement's aftermath. The inaugural session convened with 20 delegates from six regional conferences, marking the formal transition from informal associations to a centralized yet decentralized designed to facilitate expansion without hierarchical overreach. This structure was influenced by pragmatic considerations of legal incorporation for and doctrinal consistency, as early Adventists faced legal challenges in states like . Over time, reorganizations—such as the 1901 restructuring prompted by Ellen White's counsel to decentralize authority—refined its operations to balance global oversight with local autonomy. The General Conference operates through a quadrennial cycle of sessions, with the plenary General Conference Session held every five years as the supreme legislative and electoral body, where delegates from and divisions vote on policies, budgets, and . Between sessions, an Executive Committee of about 300 members, including division and union officers, handles administrative duties and convenes Annual Councils for interim decisions. The church's cascades downward: from the General Conference through 13 regional divisions (e.g., North American, Inter-American), to conferences, local conferences, and individual churches, ensuring representation proportional to membership. Key functions include coordinating global initiatives like disaster relief via ADRA, educational standards through over 8,000 schools and universities, and healthcare networks, while upholding doctrines such as the seventh-day and imminent of Christ. Recent sessions illustrate its adaptive role; the 61st Session in 2022 was abbreviated to six hybrid days in due to disruptions, focusing on virtual participation for thousands of delegates. The forthcoming 62nd Session, scheduled for July 3–12, 2025, in , , anticipates in-person attendance with the theme "Jesus is Coming, I Will Go," electing officers for the 2025–2030 term amid discussions on evangelism strategies and administrative compliance. These gatherings have historically addressed pivotal issues, such as the 1888 session's debates on righteousness by faith, which influenced doctrinal emphases without altering core organizational principles.

People, Jobs, and Characters

George Cross (award)

The (GC) is the premier gallantry decoration in the honours system, equivalent in precedence to the [Victoria Cross](/page/Victoria Cross) but reserved for acts of exceptional bravery not in the face of an enemy. Instituted on 24 September 1940 by VI amid the Second World War, it was created to honor civilian courage, particularly in roles such as and unexploded during , filling a gap left by military-focused awards. The first recipients were announced on 30 September 1940, with early awards emphasizing heroism in extreme peril from wartime hazards like incendiary devices and structural collapses. Eligibility extends to civilians, all ranks of the armed forces, , and services personnel, with posthumous awards permitted. The criteria specify "acts of the greatest heroism or of the most conspicuous in circumstance of extreme danger," typically involving non-operational scenarios such as defusing explosives, rescuing from fires or floods, or confronting terrorists without combat involvement. Unlike lower-tier awards like the , the GC demands unparalleled self-sacrifice, often where death was highly probable; recommendations originate from eyewitness accounts or official inquiries and require sovereign approval via the . The medal, designed by sculptor Percy Metcalfe, comprises a plain silver cross measuring 44 mm, suspended from a dark blue ribbon. The obverse features Saint George slaying the dragon encircled by "For Gallantry" and the sovereign's cypher; the reverse bears the recipient's name, rank (if applicable), and date of the deed. It superseded the Empire Gallantry Medal and later incorporated exchanges from the Edward Medal (for mine/rescue bravery) and Albert Medal (for lifesaving), allowing prior holders to adopt the GC retroactively to unify civilian gallantry recognition. Over its history, VI approved 114 individual GCs, while authorized 33 for UK-based acts (excluding collectives), reflecting the award's rarity amid post-war decline in qualifying incidents. Approximately 160 original awards have been made directly, including about 86 posthumous, with over 240 exchanges from predecessor medals; recipients total around 400 individuals when including these, plus three collectives to groups. to women number 12, and some foreign-born personnel serving with units, such as Belgian and agents in wartime , have received it. Collective grants underscore communal valor: received one in April 1942 for enduring over 3,000 air raids, now emblazoned on its ; the Royal Ulster Constabulary in 1999 for anti-terrorism service amid ; and the UK's on 5 July 2021 for frontline response to the , encompassing millions of staff across , , , and . Individual examples include early WWII bomb disposal officers facing improvised devices in urban areas and modern cases like Royal Marine in 2017 for shielding civilians from gunfire in . No honorary awards exist, maintaining the GC's focus on verified, life-risking acts over symbolic gestures.

Entertainment

Group chat (media)

Group Chat is an reality television series produced by , featuring social media influencers hosting discussions, games, and challenges centered on contemporary trends and . The program debuted on May 23, 2020, with initial episodes co-hosted by influencers Annie LeBlanc and , who engaged guests in remote-style conversations mimicking rooms. In later installments, Bartels transitioned to co-hosting alongside , maintaining the format of interactive segments including physical challenges and trend commentary. The series, which ran for a single season concluding in late 2020, targeted preteens and teens through its blend of talk and , often incorporating viral elements like TikTok dances and app-based games. Episodes typically featured surprise celebrity guests from the influencer , emphasizing casual banter over structured narratives. Critics noted its appeal to young audiences familiar with online group dynamics but critiqued its superficial engagement with topics, rating it moderately at 4.6 out of 10 on based on viewer feedback from 82 users. In 2025, the title Group Chat also applied to distinct media projects, including a pilot ordered on April 2 for a series starring , depicting affluent women in their 40s whose private messaging reveals personal discord beneath public personas. Separately, creator Sydney Jo Robinson's viral skit series The Group Chat, launched in March 2025, portrayed a fictional friend group's text-based meltdown over , amassing millions of views and attention from outlets like for its relatable portrayal of interpersonal tensions. These later works highlight evolving interpretations of "group chat" as a device in digital-era storytelling, distinct from the iteration's live-audience focus.

Other Uses

Get cancer (slang)

"Get cancer" is an English-language expression functioning as a severe , explicitly wishing upon the recipient the contraction of cancer, a malignant responsible for approximately 10 million deaths worldwide in 2020 according to data. The phrase conveys extreme hostility in online arguments, often in anonymous or pseudonymous settings where social repercussions are minimized, such as multiplayer video game chats or comment sections. Its usage underscores the desensitization to serious medical conditions in digital spaces, where hyperbolic curses replace measured discourse. The term gained visibility in gaming communities during the mid-2010s, with documented instances in forums discussing titles like , where players invoked it to denounce opponents or strategies perceived as frustrating. A notable case occurred on May 25, 2018, when and game critic (John Bain) publicly tweeted the phrase at a detractor amid a dispute over game journalism ethics, prompting backlash for its callousness and highlighting tensions between online and . Bain, who himself battled terminal cancer at the time and died in May 2018 from complications related to the disease, later clarified the context but faced criticism for escalating rhetoric in heated exchanges. Related variants include abbreviated or metaphorical uses of "cancer" to label something as irredeemably harmful or low-quality, such as deeming a iteration or mechanic "cancerous," but "get cancer" retains a direct, personal malediction absent in these dilutions. This parallels in other s, like Dutch "kanker op" (literally "cancer off" or "get cancer"), a commonplace reflecting cultural normalization of disease-based despite its morbidity. Critics, including cancer survivors and groups, argue such trivializes the of patients—evidenced by over 19 million new cases annually—and perpetuates , though proponents in subcultures view it as venting unbound by real-world .

Gender critical

Gender critical is a philosophical stance asserting that human is binary, immutable, and determined by reproductive function—specifically, the production of small gametes () by males and large gametes (ova) by females—with no third in humans. This view holds that cannot be altered by medical interventions, social transition, or self-identification, as chromosomes, gametes, and secondary sex characteristics remain unchanged despite or surgery. Proponents argue that recognizing as a material is essential for safeguarding sex-based rights, particularly women's protections in areas like prisons, , and domestic violence shelters, where male physical advantages persist post-puberty. The position emerged prominently in the mid-2010s amid debates over self-identification policies, such as proposed reforms to the UK's , which critics contended would undermine female-only spaces by allowing males to legally change based on declaration alone. advocates prioritize over subjective claims, citing biological dimorphism in traits like skeletal structure, muscle mass, and injury rates in contact sports, which justify -segregated categories to ensure fairness and safety. They contend that conflating with erodes causal distinctions rooted in and , potentially increasing risks such as or in female facilities, as documented in cases involving self-identified males. In legal contexts, gender critical beliefs gained recognition as protected under the UK's following the 2021 Employment Appeal Tribunal ruling in Forstater v CGD Europe, which determined that Maya Forstater's views—that sex is real, women are adult human females, and cannot override sex-based protections—constitute a philosophical worthy of in a democratic society, not incompatible with human dignity or likely to conflict with others' rights. A subsequent 2022 tribunal found Forstater suffered direct and after losing her consultancy role due to her tweets expressing these views. This overturned a 2019 preliminary ruling deeming the beliefs non-protected. Scientific support draws from , where is fixed at by the presence of or chromosomes directing gonadal differentiation, with (DSDs) representing rare developmental variations within the binary, not a spectrum erasing it—99.98% of humans fit male or female categories without ambiguity in production. The 2024 Cass Review, commissioned by , underscored evidential weaknesses in pediatric gender services, finding low-quality studies on blockers and hormones, leading to recommendations against routine use and emphasizing in assessments over rapid affirmation of identity. It highlighted a surge in adolescent referrals—over 5,000 in 2019-2020, predominantly females—without robust causal explanations tying identity to innate traits, urging caution amid potential desistance rates up to 80-90% in pre-pubertal cases. Prominent figures include researcher , whose case catalyzed awareness; philosopher , who resigned from the in 2021 after protests over her critiques of gender self-ID in university policies; and author , who in 2020 publicly defended sex-based rights amid backlash. Opponents, often from advocacy groups and aligned institutions, label these views "transphobic" or harmful, but gender critical proponents counter that such characterizations sidestep biological facts, noting institutional biases in media and academia that amplify narratives while marginalizing dissent, as evidenced by censored debates and professional repercussions. Policy impacts include Scotland's 2023 block on self-ID legislation and ' 2023 restrictions on male-advantage retention in female events, aligning with data on persistent testosterone-driven performance gaps.

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