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Group 12 element

Group 12 elements, also known as the zinc group, comprise (Zn, 30), (Cd, 48), mercury (Hg, atomic number 80), and the synthetic (Cn, 112). These d-block elements feature a filled (n-1)d¹⁰ subshell and ns² valence electrons in their neutral state, resulting in a predominant +2 and properties that distinguish them from typical transition metals, as they lack partially filled d orbitals in their common ions. The lighter members—zinc, , and mercury—are soft, silvery-white metals with relatively low and points compared to other d-block elements, reflecting weak due to the tightly held electrons. has a of 419.53°C and of 7.14 g/cm³, melts at 321.07°C with a of 8.65 g/cm³, and mercury is unique as the only metal liquid at , with a of -38.83°C and of 13.534 g/cm³. These elements occur naturally, primarily in ores such as blende (ZnS) for and (HgS) for mercury, with often obtained as a byproduct of processing; their crustal abundances decrease down the group, from 75 ppm for to 0.05 ppm for mercury. Chemically, Group 12 elements exhibit similarities to alkaline earth metals in their +2 compounds, forming ionic halides that become increasingly covalent down the group, and showing a strong affinity for soft ligands like and . and react readily with acids and oxygen to form amphoteric oxides, while mercury requires higher temperatures for oxidation and forms the distinctive Hg₂²⁺ in +1 compounds. Applications include in galvanizing and alloys like , in rechargeable batteries (though increasingly phased out due to ), and mercury in historical thermometers and the chlor-alkali process (phased out globally by 2025), despite environmental concerns over its . Copernicium, synthesized in 1996 by a team via heavy-ion , is highly radioactive with isotopes like ²⁸⁵Cn having half-lives of seconds, limiting experimental study to predicted based on relativistic quantum calculations. Theoretical predictions suggest would be a volatile at with a +2 , exhibiting gas-like due to relativistic effects stabilizing its 7s electrons, deviating from typical group 12 behavior. Overall, the group highlights trends in metallic character and reactivity influenced by increasing atomic size and , with practical and toxicological significance in and .

Introduction

Characteristics

The group 12 elements of the periodic table consist of (Zn, atomic number 30), (Cd, 48), mercury (Hg, 80), and (Cn, 112). These are d-block metals distinguished by their completely filled d subshell in the , with an of noble gasd^{10} ns^2, which imparts properties more characteristic of main-group elements than those of typical transition metals with incomplete d orbitals. The dominant across the group is +2, resulting from the facile loss of the ns^2 valence electrons, while access to d electrons for higher oxidation states is limited due to the stable closed-shell configuration. Zinc and appear as silvery-white metals with a bluish tinge, and malleable at , reflecting their despite the full d subshell weakening interatomic interactions compared to earlier d-block groups. , however, is the only metal that remains at standard conditions, its silvery appearance and fluidity stemming from particularly weak influenced by relativistic stabilization of the electrons. , entirely synthetic and produced in trace amounts via reactions, lacks observed , but computational models predict it as a volatile under ambient conditions, with a of approximately 283 K and of 340 K, arising from strong relativistic effects that contract the 7s orbital and expand the 6d, yielding a akin to mercury's alongside noble-gas-like insulating behavior marked by a 6.4 and dispersion-dominated cohesion. Owing to their d^{10} configuration, group 12 elements exhibit traits, including behaviors reminiscent of p-block elements such as restricted variability and a propensity for covalent or amphoteric compound formation rather than the diverse coordination chemistry of true transition metals. They also show a with group 2 elements, notably and magnesium, where comparable charge-to-radius ratios foster similar reactivities, as seen in the influence of zinc(I) complexes on the development of stable magnesium(I) dimers. This positions group 12 as a bridge between transition and main-group chemistries, with copernicium's relativistic deviations further emphasizing the group's evolving properties down the period.

Position in the periodic table

Group 12 elements occupy the 12th column of the periodic table within the d-block, situated between group 11—comprising the copper, silver, and —and , which initiates the post-transition metals. This placement aligns them with other d-block elements in groups 3 through 12, where the (n-1)d subshell is progressively filled across the periods. The general electronic configuration of these elements is ns^2 (n-1)d^{10}, characterized by a completely filled d subshell and two valence s electrons, which distinguishes their electronic structure from earlier d-block groups that exhibit partially filled d orbitals. This configuration contributes to their reactivity patterns, primarily involving the loss of the ns electrons to form +2 oxidation states, while the d electrons remain largely uninvolved in bonding. For the heavier members, particularly mercury, the inert pair effect begins to manifest, stabilizing the ns² electrons and reducing their participation in chemical bonds compared to lighter analogs like zinc. Due to the full d¹⁰ subshell in both neutral atoms and common ions (e.g., Zn²⁺ with [Ar] 3d¹⁰), group 12 elements lack the incomplete d subshell required by the IUPAC definition of transition metals, leading to their frequent classification alongside main-group metals despite their d-block position. This absence of d-orbital involvement in bonding results in properties more akin to post-transition metals, such as lower melting points and limited variable oxidation states, setting them apart from groups 3–11./Descriptive_Chemistry/Elements_Organized_by_Block/3_d-Block_Elements/1b_Properties_of_Transition_Metals/General_Trends_among_the_Transition_Metals) In mercury and the superheavy copernicium, relativistic effects significantly alter these trends through s-orbital contraction, where high nuclear charge accelerates inner electrons, increasing their effective mass and shrinking the 6s (Hg) or 7s (Cn) orbitals, thereby elevating ionization energies (e.g., Hg 6s binding energy of 8.92 eV relativistically vs. 7.10 eV non-relativistically). This contraction stabilizes the valence s electrons, enhancing the inert pair effect and reducing metallic bonding strength in mercury, contributing to its liquid state at room temperature. For copernicium, these effects are amplified by its superheavy nature, predicting a highly volatile noble-liquid behavior with a melting point around 10°C and boiling point near 67°C, alongside potential d-character in bonding that deviates from typical group 12 trends due to nuclear instability and short isotope half-lives (up to 29 seconds).

Physical properties

Atomic properties

The group 12 elements— (Zn), (Cd), (Hg), and the synthetic (Cn)—exhibit a common of ns^2 (n-1)d^{10}, where the filled d subshell contributes to their relatively stable +2 , though relativistic effects become prominent in the heavier members. This arises from the addition of two s electrons outside a closed d , distinguishing them from typical metals with partially filled d orbitals. The masses and full electron are summarized below, with values for Cn being theoretical predictions based on relativistic quantum calculations.
ElementAtomic NumberAtomic Mass (u)Electron Configuration
Zinc (Zn)3065.38[ \ce{Ar} ] 3d^{10} 4s^2
Cadmium (Cd)48112.41[ \ce{Kr} ] 4d^{10} 5s^2
Mercury (Hg)80200.59[ \ce{Xe} ] 4f^{14} 5d^{10} 6s^2
Copernicium (Cn)112285 (predicted)[ \ce{Rn} ] 5f^{14} 6d^{10} 7s^2 (predicted)
Atomic radii generally increase down the group due to additional electron shells, but the trend is irregular owing to contraction effects. The covalent atomic radii are 134 pm for Zn, 151 pm for Cd, and 155 pm for Hg, reflecting a modest expansion from Cd to Hg compared to the larger jump from Zn to Cd. This similarity in size between Cd and Hg results from the , where the poor shielding by 4f electrons in the lanthanide series leads to a stronger , compressing the 5d and 6s orbitals of Hg and minimizing the expected radial increase. For Cn, relativistic effects cause further s-orbital contraction, yielding a predicted of approximately 120 pm, smaller than that of Hg despite the higher . The first ionization energies (IE) follow a non-monotonic trend: 906 /mol for Zn, 868 /mol for Cd (the lowest in the group), and 1007 /mol for Hg, with Cn predicted at around 1155 /mol. The dip at Cd arises from its larger size and weaker nuclear attraction, while the rise at Hg and especially Cn stems from relativistic stabilization of the ns electrons, making them harder to remove. The second ionization energies, which involve removing an from the stable d^{10} configuration to form the M^{2+} , are significantly higher: 1733 /mol for Zn, 1631 /mol for Cd, and 1810 /mol for Hg, underscoring the energetic favorability of the +2 state across the group. Electron affinities for group 12 elements are notably low, typically near 0 kJ/mol or slightly endothermic (positive values), as exemplified by Zn (≈0 kJ/mol) and (≈0 kJ/mol), with Hg showing a small negative value around -50 kJ/mol in some measurements. This trend reflects the filled shells and metallic character, where adding an to form a negative is unfavorable due to increased electron-electron repulsion in the compact orbitals.

Bulk properties

Group 12 elements exhibit a range of physical properties that reflect their position in the periodic table, with zinc and cadmium behaving as typical metals and mercury as the only metallic element that is liquid at . These properties include phase transition temperatures, densities, conductivities, and crystal structures, which vary significantly down the group due to increasing atomic size and relativistic effects in heavier members. , the synthetic , has properties predicted through computational methods, indicating it may differ markedly from its homologues. Predictions for are based on relativistic (DFT) calculations due to its short preventing direct measurement. The melting and boiling points decrease down the group, highlighting the trend toward weaker in heavier elements. Zinc has a melting point of 419.5 °C and a boiling point of 907 °C, while melts at 321.1 °C and boils at 767 °C; mercury, in contrast, melts at -38.8 °C and boils at 356.7 °C. Densities increase with atomic mass, from 7.14 g/cm³ for to 8.65 g/cm³ for and 13.53 g/cm³ for mercury. For , (DFT) calculations predict a density of approximately 13.7 g/cm³, similar to mercury.
Element (°C) (°C) (g/cm³)
419.59077.14
321.17678.65
Mercury-38.8356.713.53
(predicted)~10~67~13.7
and display high electrical and thermal conductivities typical of post-transition metals, with at 116 W/(m·) thermal and about 27% IACS electrical, and at 96.6 W/(m·) thermal and 22% IACS electrical; mercury's values are lower at 8.34 W/(m·) thermal and 1.7% IACS electrical, attributable to its liquid state disrupting efficient and transport. In their solid forms, and adopt a hexagonal close-packed (hcp) , facilitating dense packing and metallic properties, whereas solid mercury has a more complex rhombohedral due to directional bonding influenced by relativistic effects. For , recent DFT-based free-energy calculations suggest it may exist as a volatile under standard conditions, with no stable crystalline phase at , potentially exhibiting body-centered cubic (bcc) or hcp structures if solidified, though experimental verification remains elusive.

Chemical properties

The elements of group 12—zinc (Zn), (Cd), (Hg), and (Cn)—exhibit periodic trends in their physical and chemical properties that deviate from typical d-block behavior due to their filled d¹⁰ electronic configurations and increasing relativistic effects down the group. Reactivity decreases from Zn to Hg, as evidenced by the standard reduction potentials for the M²⁺/M couples, which become less negative: Zn²⁺ + 2e⁻ → Zn (E° = -0.76 V), Cd²⁺ + 2e⁻ → Cd (E° = -0.40 V), and Hg²⁺ + 2e⁻ → Hg (E° = +0.85 V). This trend reflects the increasing nobility of the metals, with Zn being the most reactive and readily oxidized, while Hg is resistant to oxidation under standard conditions. For Cn, theoretical predictions suggest even lower reactivity, potentially resembling a noble metal due to enhanced relativistic stabilization of the 7s orbitals. Experimental gas-phase studies, such as adsorption on gold surfaces in 2016, indicate Cn is more noble than Hg, aligning with predictions (as of 2024). A key anomaly in atomic properties arises in the first ionization energies (IE₁), which do not monotonically decrease down the group as expected from increasing atomic size. Zn has IE₁ = 9.39 eV, Cd = 8.99 eV, but Hg = 10.44 eV, higher than Zn's due to relativistic effects that contract the 6s orbital and increase effective nuclear charge on the valence electrons. These effects, including spin-orbit coupling and the Darwin term, become pronounced for Hg, stabilizing the closed-shell Hg²⁺ ion and contributing to its low reactivity. For Cn, relativistic influences are expected to be even stronger, yielding an IE₁ of approximately 12 eV, higher than Hg's and further reducing reactivity. Oxidation states in group 12 are predominantly +2, consistent with the ns² , though +1 is and observed mainly in Hg as the Hg₂²⁺ dimer. No +3 state is common across the group, as it would require promotion from the stable d¹⁰ subshell. For Cn, calculations predict +2 as the most stable, with +1 possible but unlikely, and +4 potentially accessible under specific conditions due to 7p involvement, though not observed experimentally. on the Pauling scale increases slightly from Zn (1.65) to Cd (1.69) and more notably to Hg (2.00), reflecting the relativistic contraction that enhances Hg's attraction for electrons. Cn's is predicted to be in the range of 1.5–2.0, likely closer to Zn and Cd due to balancing relativistic and effects in the 7th period. The stability of group 12 hydrides decreases dramatically down the group, highlighting trends in M–H bonding strength. ZnH₂ decomposes slowly at and rapidly above 90 °C, forming polymeric structures; CdH₂ decomposes above -20 °C; and HgH₂ is highly explosive, detonating upon slight warming or shock. This trend correlates with weakening M–H bonds from relativistic stabilization of the metal's s electrons, reducing their availability for hydride formation. For CnH₂, theoretical models suggest even lower stability, potentially existing only in matrix isolation.
PropertyZnCdHgCn (predicted)
First Ionization Energy (eV)9.398.9910.44~12
Electronegativity (Pauling)1.651.692.00~1.5–2.0
E° (M²⁺/M) (V)-0.76-0.40+0.85<<0

Classification and bonding

Group 12 elements— (Zn), (Cd), (Hg), and (Cn)—are classified as post-transition metals, despite their position in the d-block of the periodic table. This designation arises from their filled d¹⁰ electronic configuration in the +2 , which renders the d electrons inert and unavailable for bonding, leading to chemical behavior more akin to p-block main-group metals than typical transition metals with variable s and d-orbital involvement. Lighter members like Zn and Cd exhibit predominantly metallic character, while heavier ones, particularly Hg, display increasing covalent tendencies due to relativistic effects stabilizing the ns orbitals and enhancing s-electron participation in bonds. The bonding in group 12 elements varies with the nature of the ligands and the element involved. In lighter members, compounds such as zinc oxide (ZnO) and (Zn(OH)₂) feature predominantly , characterized by high lattice energies and the transfer of electrons from the metal to oxygen, though with some covalent character due to the moderate difference. In contrast, organometallic compounds across the group, such as dimethylzinc ((CH₃)₂Zn) and ((CH₃)₂Hg), exhibit covalent M–C bonds, where electron sharing dominates owing to the low and sp³-hybridized carbon atoms. Mercury compounds, including HgCl₂ and HgS, further emphasize covalent bonding, influenced by the and relativistic contraction of the 6s orbital, which promotes weaker, more directional bonds over ionic lattices. In coordination chemistry, group 12 elements in the +2 oxidation state prefer tetrahedral geometries for four-coordinate complexes, a consequence of their d¹⁰ configuration, which lacks crystal field stabilization energy preferences that favor octahedral or square planar arrangements in other transition metals. For instance, the tetrachlorozincate ion, [ZnCl₄]²⁻, adopts a tetrahedral structure to minimize steric repulsion among ligands, as the closed-shell d orbitals impose no directional bonding constraints. This geometric preference extends to Cd and Hg analogs, such as [CdCl₄]²⁻ and [HgI₄]²⁻, reinforcing the post-transition metal character. Unlike typical transition metals, group 12 elements lack variable oxidation states beyond +2 (and rarely +1 for Hg), as the stable d¹⁰ ns² ground state and high ionization energies prevent access to higher or d-involving states. Theoretical studies on highlight its divergence from lighter homologs, predicting enhanced volatility and gas-like inertness due to extreme relativistic effects stabilizing the 7s² and weakening . First-principles calculations indicate Cn exists as a volatile near , with a predicted of approximately 283 K and of 340 K, and minimal reactivity toward or chalcogens, resembling more than mercury in its low cohesion and diatomic tendencies in the gas phase. These predictions stem from free-energy simulations accounting for spin-orbit coupling, underscoring Cn's potential as a relativistic rather than a conventional . Experimental gas-phase studies, such as adsorption on surfaces in 2016, indicate Cn is more than Hg, aligning with predictions (as of 2024).

Comparison with group 2 elements

Group 12 elements, zinc (Zn), cadmium (Cd), and mercury (Hg), exhibit notable similarities to the group 2 alkaline earth metals (Be, Mg, Ca, Sr, Ba) primarily due to their shared +2 oxidation state and tendency to form divalent compounds. Both groups predominantly achieve the +2 oxidation state by losing their ns² valence electrons, leading to analogous ionic species like Zn²⁺ and Mg²⁺ or Cd²⁺ and Ca²⁺. For instance, oxides such as ZnO and MgO are both refractory solids used in similar applications, reflecting comparable ionic bonding in these compounds. A key similarity arises from a diagonal relationship between group 12 and group 2 elements, driven by comparable ionic radii and charge densities for their +2 cations. The ionic radius of Zn²⁺ (74 pm) is close to that of Mg²⁺ (72 pm), while Cd²⁺ (95 pm) resembles Ca²⁺ (100 pm), and Hg²⁺ (102 pm) aligns with Sr²⁺ (118 pm) or Ba²⁺ (135 pm), resulting in similar solubilities and reactivities for compounds like sulfates and carbonates. This proximity in size leads to parallel trends in lattice energies and precipitation behaviors, such as the decreasing solubility of sulfates down both groups. Despite these parallels, group 12 elements display greater covalent character in their compounds compared to the more ionic nature of group 2. Higher electronegativities in group 12—Zn (1.65), (1.69), (2.00) versus (1.31), (1.00), (0.95)—promote polarization of bonds, enhancing covalency, particularly in Hg compounds. This is evident in the amphoteric behavior of group 12 hydroxides and oxides, unlike the predominantly basic group 2 counterparts; for example, Zn(OH)₂ dissolves in both acids and strong bases to form [Zn(OH)₄]²⁻, while Mg(OH)₂ is insoluble in bases. The d¹⁰ electron configuration in group 12 contributes to this distinction by increasing and poor shielding, which heightens polarization despite similar charge densities to group 2 ions. Consequently, group 12 hydrides, such as ZnH₂, are less stable and more covalent than the ionic hydrides of group 2 (e.g., MgH₂), decomposing readily at lower temperatures. Similarly, group 12 oxides like ZnO exhibit , reacting with acids and bases, whereas group 2 oxides like MgO remain basic. These differences underscore the transitional position of group 12, blending main-group ionic traits with d-block covalency.

Characteristic compounds

Group 12 elements form a variety of characteristic compounds that highlight their transition from metallic to more covalent and volatile behavior down the group. The oxides, halides, sulfides, and organometallic derivatives exemplify these trends, with properties influenced by the d¹⁰ electronic configuration and increasing relativistic effects in heavier members. The oxides of zinc, cadmium, and mercury display acid-base properties that shift from amphoteric to basic to unstable. Zinc oxide (ZnO) is amphoteric, dissolving in acids to form salts like zinc chloride and in strong bases to produce zincates, such as Na₂ZnO₂. It forms via the combustion of zinc:
$2\mathrm{Zn} + \mathrm{O_2} \rightarrow 2\mathrm{ZnO}
Cadmium oxide (CdO) exhibits basic character, reacting with acids to yield cadmium salts but showing limited solubility in bases. Mercury(II) oxide (HgO), a red or yellow solid, is thermally unstable and decomposes readily upon heating above 500 °C:
$2\mathrm{HgO} \rightarrow 2\mathrm{Hg} + \mathrm{O_2}
This endothermic decomposition was historically significant in the isolation of oxygen gas.
Halides of group 12 elements demonstrate increasing covalent character and Lewis acidity variations. Zinc chloride (ZnCl₂), a white hygroscopic solid, acts as a Lewis acid by accepting electron pairs from donors, forming tetrahedral complexes like [ZnCl₄]²⁻; it catalyzes reactions such as the Fischer esterification due to this property. In contrast, mercury(II) chloride (HgCl₂) is a covalent molecular compound with a linear Cl–Hg–Cl geometry, arising from the sp hybridization of the d¹⁰ Hg²⁺ center; it hydrolyzes slowly in water and is noted for its toxicity. Sulfides represent key minerals and industrial materials for lighter group 12 elements. (ZnS) occurs in two polymorphs: (cubic zinc blende structure) and (hexagonal), both featuring tetrahedral Zn–S coordination; it serves as a white in paints and a in luminescent applications due to its wide . (CdS) forms a hexagonal lattice and is prized as a bright yellow (cadmium yellow) in artists' oils and ceramics, though its use has declined due to concerns. Organometallic compounds of group 12 elements are highly reactive, with and increasing down the group. Dialkylzinc reagents, such as dimethylzinc (Zn(CH₃)₂), are pyrophoric and air-sensitive, undergoing rapid exothermic reactions with oxygen or water to form and hydrocarbons; they are employed in asymmetric synthesis and polymerizations as nucleophilic alkylating agents. Alkylmercury derivatives, exemplified by ((CH₃)₂Hg), exhibit strong covalent bonding and extreme , readily penetrating skin and bioaccumulating to cause severe neurological damage via inhibition of enzymes like . For (Cn), the heaviest group 12 element, no compounds have been synthesized experimentally, but relativistic quantum chemical calculations predict noble-gas-like behavior due to strong scalar-relativistic stabilization of the 7s² orbitals. monoxide (CnO) is expected to be volatile, with properties akin to a weakly bound diatomic species rather than a stable solid oxide. In contrast, copernicium difluoride (CnF₂) is predicted to be thermodynamically stable, with a formation energy of -2.5 relative to atomic Cn and F₂, owing to relativistic enhancement of Cn–F bonding; higher fluorides like CnF₄ may also form under extreme conditions. These predictions, from 2019 models incorporating spin-orbit coupling, remain unverified but highlight Cn's deviation from mercury-like chemistry. Experimental gas-phase studies, such as adsorption on surfaces in 2016, indicate Cn is more than Hg, aligning with predictions (as of 2024).

History

Zinc

Zinc has been utilized in ancient civilizations primarily through its with , known as , dating back to approximately 1000 BCE in regions of and . Archaeological evidence from sites like in , , indicates that early production involved the , where zinc ore () was heated with to form the , enabling its use in artifacts such as ornaments and tools. Recent archaeological investigations in the 2020s have further substantiated the antiquity of zinc processing, confirming and preliminary activities as early as the BCE at sites in the region, predating previous estimates. In , began in the 1500s, with the first recorded workings at Worle in the , , in 1566, supporting the growing industry. The recognition of zinc as a distinct element occurred in the 16th century, when the Swiss-German alchemist (1493–1541) first referred to it as "zincum" around 1526, deriving the name from the German word "Zinke," meaning prong or tooth, due to the sharp, pointed crystals formed during . Pure metallic was isolated in 1746 by German chemist , who achieved this by reducing calamine (zinc oxide) with charcoal in a closed , preventing oxidation and vapor loss. The chemical symbol Zn was formally adopted in 1813 as part of Jöns Jacob Berzelius's system of elemental notation, abbreviating the Latin "zincum."

Cadmium

Cadmium was discovered in 1817 by the German chemist Friedrich Stromeyer, a professor at the , while investigating impurities in samples supplied to local pharmacies for medicinal use. Stromeyer noticed that certain batches of the , sourced from the area, produced an unexpected brown residue upon heating, which he traced to a previously unknown metallic impurity. Independently in the same year, Karl Samuel Leberecht Hermann, a manufacturer in Schönebeck, identified the same element in zinc oxide from his factory after Johann Roloff raised concerns about its purity. This incidental finding highlighted cadmium's close association with , as it occurred as a trace contaminant in zinc ores, contrasting with zinc's long history of deliberate extraction and use dating back to ancient times. Stromeyer isolated the new element by distilling the residue from heated , collecting the volatile metallic vapors that condensed into a silvery-white solid distinct from . He named it "cadmium" after the Greek term "kadmeia," the ancient name for ( ore), reflecting its origin as a of processing. Hermann confirmed the discovery through similar distillation experiments on ores, solidifying 's identification as a distinct with properties intermediate between and mercury. The Cd for was adopted in 1818, shortly after its , as part of early efforts to standardize elemental in chemical literature. During the , expanding smelting operations in —driven by demand for and alloys—frequently yielded cadmium-rich residues in furnace condensates and , prompting further characterization of the element as a common zinc contaminant. By the 1840s, was recognized for its vibrant yellow hue and developed as the pigment cadmium yellow, though its scarcity initially limited production; early accounts noted its toxicity akin to other compounds used in artists' materials.

Mercury

Mercury has been known and utilized since ancient times, with evidence of its use dating back to around 2000 BCE in , where it served as a contraceptive and in early medicinal applications. In , liquid was discovered in tombs from approximately 1500 BCE, often in ceremonial contexts, while amalgams involving mercury with metals like tin and were employed for decorative purposes. By the time of in the 4th century BCE, mercury was recognized as a distinct substance, described in philosophical texts as a used in religious ceremonies. Its purification methods, including early extraction techniques from ore, were documented by , Aristotle's successor, involving grinding the ore with and to yield metallic mercury. The element's name derives from the Roman god Mercury, reflecting its swift, fluid nature, while the Latin term hydrargyrum—meaning "liquid silver" or ""—captures its appearance and mobility. This Latin influenced the Hg, formally adopted in the modern periodic system proposed by in 1813–1814, standardizing one- or two-letter abbreviations derived from Latin or Greek roots. In alchemical traditions spanning the through the medieval era, mercury held a central role as a , believed essential for transmuting base metals into gold via the ; alchemists in and experimented extensively with it for elixirs of immortality and universal solvents. , in the 1st century CE, noted mercury's toxicity, warning of the harmful vapors from processing that endangered miners, an early recognition of its health risks despite its mystical allure. He also described methods for recovering , involving heating the ore to volatilize and condense the metal, marking a key advancement in its isolation. By the 18th and 19th centuries, mercury's practical applications expanded dramatically in scientific instruments, becoming ubiquitous in s and s. introduced the mercury in 1714, leveraging its uniform expansion to create precise temperature scales that replaced less reliable alcohol-based devices. Evangelista Torricelli's 1643 invention of the mercury , refined over the following centuries, enabled accurate atmospheric pressure measurements essential for and , with wheel and angle barometers adorning homes and observatories across . These devices solidified mercury's role in the , facilitating advancements in physics and weather prediction until toxicity concerns prompted safer alternatives in the .

Copernicium

Copernicium (Cn) is a synthetic in group 12 of the periodic table, with 112. It was first synthesized on February 9, 1996, at the GSI Helmholtz Centre for Heavy Ion Research in , , through the fusion of lead-208 and zinc-70 isotopes in a heavy-ion accelerator: ^{208}\mathrm{Pb} + ^{70}\mathrm{Zn} \rightarrow ^{277}\mathrm{Cn} + n. This reaction produced the isotope copernicium-277, which decays via alpha emission with a of approximately 0.24 milliseconds, confirming its identification through the subsequent to known isotopes. The discovery was independently verified in 2004 by researchers at in using the same reaction, and the International Union of Pure and Applied Chemistry (IUPAC) officially recognized the GSI team as the discoverers on May 19, 2009. The element was named in honor of the Polish astronomer (1473–1543), whose heliocentric model revolutionized astronomy, on the 537th anniversary of his birth, February 19, 2010. The name and symbol Cn were approved by IUPAC, following the tradition of honoring scientists, and replaced the temporary placeholder ununbium (Uub). This naming reflects copernicium's position as a at the end of group 12, extending the series beyond , , and mercury. Eight isotopes of have been confirmed, ranging from copernicium-277 to copernicium-285, with the most stable being copernicium-285, which has a of about 29 seconds and decays primarily by alpha emission. Lighter isotopes, such as the isotope copernicium-277, have half-lives on the order of milliseconds. In 2025, researchers at the (JINR) in , , synthesized copernicium-280 using advanced facilities like the Superheavy Element Factory, contributing to ongoing efforts to explore neutron-deficient isotopes near predicted regions of enhanced stability. Due to the extreme and low yields—typically only a few atoms per experiment—'s properties are studied indirectly through and theoretical modeling rather than direct bulk measurements. These challenges limit experimental data, with atoms observed only fleetingly in specialized detectors, necessitating predictions for chemical behavior, such as potential akin to mercury but enhanced by relativistic effects. Recent JINR experiments, including the 2025 , support predictions of slightly longer-lived heavier isotopes (e.g., beyond mass 290) and refined models indicating may form a noble liquid at .

Occurrence and production

Natural occurrence

Group 12 elements, consisting of (Zn), (Cd), (Hg), and (Cn), exhibit varying natural abundances in , with Zn being the most prevalent at approximately 79 (ppm), ranking it as the 24th most abundant element. Cd occurs at about 0.1 ppm, while Hg is even scarcer at 0.08 ppm. In contrast, Cn has no natural occurrence, as it is entirely synthetic and produced only in laboratory settings through reactions. These elements are primarily sourced from specific mineral ores. Zn is chiefly extracted from (ZnS), a found in hydrothermal deposits and sedimentary rocks. Cd, though rare as a primary mineral in greenockite (CdS), is predominantly obtained as a from Zn ores, where it substitutes for Zn in the crystal lattice at concentrations of 0.2–0.4%. Hg occurs mainly in (HgS), a red deposited in low-temperature hydrothermal veins. In the cosmos, group 12 elements form through processes during explosions, where rapid neutron bombardment in the star's collapsing core synthesizes heavier nuclei beyond iron. Solar system abundances of Zn, for instance, are approximately 4 times higher than in , reflecting less in primitive materials like chondrites compared to the fractionated terrestrial environment. Recent analyses of carbonaceous chondrites, including isotopic studies, reveal elevated Cd concentrations—up to several times those in the crust—indicating these meteorites preserve more pristine solar compositions with less volatile loss. Environmentally, and demonstrate significant , concentrating through food chains in aquatic and terrestrial ecosystems due to their affinity for sulfhydryl groups in organisms. This process amplifies their presence in top predators, far exceeding crustal levels, though remains more evenly distributed without such pronounced .

Extraction methods

, the most abundant and industrially significant Group 12 element, is primarily extracted from (ZnS) ore through hydrometallurgical processes, which account for over 85% of global production. The ore concentrate is first roasted in air at temperatures around 900–1000°C to convert to zinc oxide, removing sulfur as gas: \text{ZnS} + \frac{3}{2}\text{O}_2 \rightarrow \text{ZnO} + \text{SO}_2 The calcine (impure ZnO) is then leached with to form soluble , followed by purification and in electrolytic cells to produce high-purity zinc metal (over 99.9%). Pyrometallurgical reduction using carbon is used in secondary processes like the imperial smelting method but represents a minority share. Global refined production was estimated at approximately 13.7 million metric tons in 2024, projected to reach 14 million metric tons in 2025, driven mainly by demand in galvanizing and alloys. Cadmium is recovered almost exclusively as a during refining, comprising about 0.2–0.5% of concentrates. In hydrometallurgical plants, is separated from leach solutions via cementation with dust, precipitating metal, or by selective precipitation as sulfate (CdSO₄) under controlled conditions. The sponge is then dissolved in , purified through further dust cementation stages, and recovered via or to produce high-purity metal (99.99%). exploits 's lower (767°C) compared to (907°C) for separation in pyrometallurgical routes. Global production, tied to output, was estimated at around 24,000 metric tons in 2024. Mercury extraction traditionally involves roasting cinnabar (HgS), its primary ore, in air at 500–600°C to volatilize mercury while oxidizing sulfur: \text{HgS} + \text{O}_2 \rightarrow \text{Hg} + \text{SO}_2 The mercury vapor is condensed and purified by , often with historical use of amalgamation for recovery aiding secondary sourcing, though modern processes emphasize direct roasting for . This method is energy-intensive, requiring significant heat input and generating SO₂ emissions that necessitate scrubbing to mitigate . Due to environmental concerns, mercury mining and use have been phased out in many countries under the , effective since 2017, which bans new mines and limits existing operations to 15 years post-ratification, promoting instead. Global primary mercury mine production was approximately 1,300 metric tons in 2024, with most supply now from byproduct recovery in refining. Copernicium (Cn), the heaviest , is not extracted from natural sources but synthesized in particle accelerators via . It is produced by bombarding a lead-208 target with zinc-70 ions at energies near the (around 5 MeV per ), forming copernicium-277 through the reaction: ^{208}\text{Pb} + ^{70}\text{Zn} \rightarrow ^{277}\text{Cn} + n Only a few atoms have been created since its in , with no industrial-scale production possible due to its short (approximately 30 seconds for the most stable ) and extreme instability; synthesis occurs at facilities like GSI Helmholtz Centre using heavy-ion accelerators.

Applications

Industrial and commercial uses

Zinc is extensively used in industry for galvanizing , where it is applied as a protective to prevent in applications such as , automotive bodies, and ; this accounts for about 60% of global zinc consumption. Additionally, zinc serves as the primary metal in die-casting processes for producing precision components in automobiles, , and household appliances, comprising roughly 15% of its usage. Cadmium is employed in to deposit a thin layer on and other metals, enhancing resistance and durability in and equipment. It is also a key component in nickel-cadmium (Ni-Cd) rechargeable batteries, valued for their reliability in high-drain applications like power tools and emergency lighting, though production has declined significantly since the early due to concerns. Mercury's industrial applications have been severely curtailed by global regulations, including the Minamata Convention on Mercury, which aims to phase out non-essential uses; historically, it was common in thermometers, sphygmomanometers, and tilt switches for its unique liquid properties at room temperature. Today, permitted uses are confined to compact fluorescent lamps (CFLs) and high-intensity discharge lamps for energy-efficient lighting in commercial and industrial settings, as well as in dental amalgams for restorative fillings due to their durability and biocompatibility. On November 7, 2025, parties to the Minamata Convention adopted an amendment to phase out mercury-added dental amalgams globally by 2034, building on the EU ban effective January 1, 2025. Copernicium, a synthetic element produced only in particle accelerators, has no industrial or commercial applications owing to its extreme instability and radioactivity, with half-lives of its isotopes ranging from milliseconds to seconds; it is exclusively utilized in fundamental research to study superheavy element chemistry and nuclear properties. Recent market trends show increasing demand for zinc driven by the expansion of renewable energy sectors, particularly in zinc-ion and zinc-air batteries for grid-scale energy storage and electric vehicles, projected to elevate its share in the battery market from 1% in 2021 to 20% by 2030. In contrast, cadmium applications remain constrained by the European Union's Restriction of Hazardous Substances (RoHS) Directive enacted in 2006, which limits its presence in electronics and promotes safer alternatives, further accelerating the decline in Ni-Cd battery production.

Alloys and materials

Group 12 elements play a significant role in various alloys and , leveraging their unique chemical properties for enhanced mechanical, thermal, and optical characteristics. Zinc, the most abundant and versatile of these elements in practical applications, forms the basis of , a -zinc typically containing 5-45% zinc, which exhibits excellent , malleability, and acoustic properties suitable for musical instruments, plumbing fittings, and decorative items. Bronze variants incorporating zinc, such as certain high-strength copper-zinc-tin alloys, provide improved wear and are used in bearings and bushings, though traditional tin bronzes dominate without zinc. Zinc-aluminum solders, often with 2-10% aluminum, enable low-temperature joining of aluminum components with good and tensile strength, around 380-420°C, and are applied in automotive and repairs. Cadmium alloys, though less common due to toxicity concerns, include low-melting fusible compositions such as (50% , 26.7% lead, 13.3% tin, 10% ), which melts at 70°C and is employed in fusible links for devices like automatic sprinklers, offering reliable activation at specific low temperatures. Mercury, known for its liquid state, forms amalgams that were historically crucial in , where elemental mercury bound fine particles into a malleable amalgam for separation from , a process widely used from the 19th century era until phased out due to environmental impacts. In dentistry, silver-tin-mercury amalgams, comprising 40-50% mercury alloyed with 50-70% silver and 20-30% tin, have been a durable filling material forming phases like Ag₂Hg₃ and Sn₇₋₈Hg for restorations, though their use is declining. Modern applications highlight advanced materials derived from group 12 elements. Zinc oxide nanoparticles, with particle sizes below 100 , are incorporated into sunscreens at 5-25% concentrations to provide broad-spectrum UV protection while minimizing the white residue of larger particles, enhancing cosmetic appeal and efficacy. (CdTe) thin-film solar cells, utilizing a polycrystalline CdTe layer approximately 1-5 μm thick on substrates, achieve efficiencies up to 22% and represent about 4% of global photovoltaic production due to their low-cost deposition via vapor transport. As of 2025, mercury-free alternatives to dental amalgams, such as composite resins and ionomers, have gained prominence following the ban on mercury-added amalgams effective January 1, 2025, promoting safer, aesthetically superior restorative options. Theoretical simulations for (), element 112, suggest relativistic effects impart noble gas-like volatility and liquidity at standard conditions, inspiring computational models for incorporation in hypothetical , such as enhanced-stability clusters for extreme-environment sensors, though practical synthesis remains infeasible due to its short of seconds.

Biological aspects

Biological roles

Zinc is an essential in living organisms, playing critical roles in numerous biochemical processes. It functions as a cofactor for over 300 enzymes, including , which is vital for transport and acid-base balance. is also indispensable for , , and protein synthesis, as well as supporting immune function by aiding in the and activation of immune cells such as T-lymphocytes and neutrophils. The recommended dietary allowance for zinc in adults is 11 mg per day for males and 8 mg per day for females, with higher requirements during and . Deficiency in zinc can lead to impaired and , particularly in children, along with delayed sexual maturation and increased to . Unlike , and mercury have no established essential biological roles in organisms and instead interfere with . competes with for uptake transporters and binding sites in enzymes, disrupting cellular . Mercury can displace from metallothioneins and other proteins, leading to imbalances in regulation. , as a synthetic and highly radioactive element, holds no biological relevance and does not participate in any physiological processes. Zinc in cells and organisms is tightly regulated by specialized transporters, including the ZIP family (SLC39) proteins, which facilitate zinc influx into the , and the ZnT family (SLC30) proteins, which mediate zinc efflux to prevent . These mechanisms ensure appropriate zinc levels for enzymatic functions while avoiding excess accumulation.

Toxicity and precautions

Group 12 elements exhibit varying degrees of , with being the least hazardous, while and mercury pose significant health risks through acute and chronic exposure. Precautions focus on limiting occupational and environmental exposures to prevent and long-term damage. , being a highly radioactive with no stable isotopes, presents negligible chemical toxicity but potential hazards during . Zinc demonstrates low compared to other group 12 elements, though excessive intake can lead to gastrointestinal distress. Oral ingestion of high doses, such as those exceeding 100 mg/kg body weight, typically induces , , and , with an estimated acute oral LD50 around 100-350 mg/kg for common zinc compounds like in animal models. Chronic overexposure may disrupt and iron absorption, but is generally well-tolerated at nutritional levels. Cadmium is a potent classified as by the International Agency for Research on Cancer, primarily linked to from inhalation but also associated with and renal cancers via chronic exposure. Prolonged low-level exposure targets the kidneys, causing proximal tubular damage, , and in severe cases, the osteomalacic condition known as , first documented in Japan's Jinzu River basin during the 1950s due to contaminated by cadmium-laden irrigation water from mining runoff. Mercury, particularly in its organic form as , acts as a potent that readily crosses the blood-brain barrier and , leading to developmental delays, sensory impairments, and motor dysfunction. bioaccumulates in aquatic food chains, concentrating in predatory fish and posing risks to consumers; the 1956 Minamata disaster in exemplified this, where industrial discharge of into contaminated seafood, affecting over 2,000 people with symptoms including , vision loss, and convulsions. Elemental and inorganic mercury primarily affect the respiratory and renal systems upon inhalation or . Occupational exposure limits established by the (OSHA) aim to mitigate these risks: the (PEL) for oxide fumes is 5 mg/m³ as an 8-hour time-weighted average (TWA), for is 5 µg/m³ TWA, and for mercury vapor is 0.1 mg/m³ ceiling. , , and monitoring are recommended to stay below these thresholds. Environmentally, cadmium and mercury are persistent pollutants that resist degradation and accumulate in sediments and biota, exacerbating toxicity through food web magnification. The European Union's REACH Regulation (EC) No 1907/2006, effective since 2007, restricts cadmium and mercury in consumer products, batteries, and to curb releases and protect ecosystems. Recent studies from 2024-2025 highlight emerging interactions between and mercury in oceans, where microplastics sorb , enhancing its and to marine organisms such as and . For instance, experiments demonstrate synergistic in copepods exposed to mercury-laden polystyrene nanoparticles, amplifying and . These findings underscore the need for integrated controls to address combined threats.

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