Fact-checked by Grok 2 weeks ago

Promega

Promega Corporation is a privately held biotechnology company founded in 1978 by Bill Linton in Madison, Wisconsin, United States, specializing in the application of biochemistry and molecular biology to develop reagents, assays, and instrumentation for life sciences research, including areas such as genomics, proteomics, cellular analysis, and drug discovery.^[1]^[2] The company, originally named Biotec before adopting its current name, has grown into a global enterprise with over 4,000 products in its portfolio, emphasizing innovative technologies like bioluminescent detection systems (e.g., NanoLuc luciferase) and enzyme inhibitors (e.g., RNasin RNase inhibitor), which support workflows in academic, pharmaceutical, and clinical laboratories.^[1]^[2] Headquartered in Madison with branches and distributors worldwide, Promega maintains a commitment to sustainable practices and custom manufacturing solutions tailored for biopharmaceutical applications, while investing in R&D to advance tools for disease prevention and cure.^[1]^[3] Promega's defining contributions include pioneering advancements in nucleic acid amplification, protein analysis, and forensic genetics tools, such as DNA IQ kits, which have become staples in research and applied settings; the firm has also engaged in patent enforcement to protect its intellectual property, as seen in resolved disputes over luciferase substrates and Taq polymerase technologies.^[1]^[4] No major ethical or operational scandals have marked its history, with its private ownership enabling long-term focus on scientific innovation over short-term shareholder pressures.^[1]

History

Founding and Early Development (1978–1980s)

Promega Corporation was founded in 1978 by William "Bill" Linton in Madison, Wisconsin, initially under the name Biotec, with the aim of supplying restriction enzymes essential for molecular biology research.^[1]^[5] Linton, motivated by the emerging biotechnology revolution, sought to enable scientists by providing tools like enzymes that could precisely cut and splice DNA, targeting academic and research applications rather than direct therapeutic development.^[6]^[7] The company's early operations were modest, operating from limited space to produce these reagents amid the rapid growth of recombinant DNA techniques. In 1979, Biotec relocated to a new 900-square-foot facility, providing expanded room for innovation and production scaling.^[2] By the early 1980s, the company rebranded to Promega, reflecting its focus on promoting genetic research tools, and introduced key products such as RNasin® RNase Inhibitor, which protected RNA in experimental assays and became a staple in molecular biology labs.^[1] This period marked Promega's establishment as a reliable supplier of high-quality enzymes and reagents, supporting foundational biotech work without venturing into proprietary drug discovery. Promega's early international outreach began in 1985 with a joint venture to establish China's first biotechnology manufacturing facility, underscoring Linton's strategy to globalize access to research tools amid rising demand from Asian scientific communities.^[5] These developments solidified the company's niche in enabling upstream biotechnology infrastructure, prioritizing empirical tool provision over speculative applications.^[6]

Expansion and Product Diversification (1990s–2000s)

In the 1990s, Promega expanded its technological capabilities through the acquisition of bioluminescent sensor technology in 1990, which enabled the development of luciferase-based products for applications in drug discovery, live-cell imaging, and environmental monitoring.^[1]^[2] This period also marked the introduction of the company's first short tandem repeat (STR) multiplex system in 1991, enhancing forensic DNA analysis tools, alongside the formation of the BioPharmaceutical Technology Center (BTC) Institute to support research and education.^[2] Facility expansion followed with the opening of the BTC manufacturing site in 1995, adding 19,000 square meters to the Madison campus and bolstering production capacity for molecular biology reagents.^[2] Product diversification accelerated with the launch of the CellTiter-Glo® Cell Viability Assay in 1998, a luminescent assay for high-throughput screening in cell-based studies, and the granting of the first luciferase patent in 1994.^[2] International outreach began with the establishment of Promega AG in Switzerland in 1991 as a branch office, facilitating European distribution.^[8] The 2000s saw further diversification into proteomics, drug metabolism assays, and automated systems, reflecting Promega's shift toward integrated solutions for research workflows. Key launches included the Caspase-Glo® 3/7 Assay in 2001 for apoptosis detection, the HaloTag® Technology in 2005 for protein labeling and purification, and the P450-Glo™ CYP450 Assay System in 2003, which earned recognition as one of R&D Magazine's Top 100 Technologies.^[2] In forensics, the DNA IQ™ System and PowerPlex® STR systems gained prominence, notably aiding the analysis of thousands of DNA samples for 9/11 victim identification in New York, with the DNA IQ™ System itself awarded as a Top 100 Technology by R&D in 2002.^[1] Automation advanced with the Maxwell® 16 instrument and reagents in 2008, streamlining nucleic acid extraction, and a direct amplification-compatible STR multiplex system that year, reducing sample preparation needs.^[2] Operational expansions included a protein production facility in Madison in 2001, supporting custom manufacturing, while innovations like RFID-enabled on-site stocking via "Promega Express" in 1999 improved supply chain efficiency for customers.^[2] These developments diversified Promega's portfolio beyond core molecular biology tools into cellular assays, bioprocessing, and forensic applications, driving revenue growth through targeted R&D investments.^[1]

Modern Growth and Strategic Initiatives (2010s–Present)

In the 2010s, Promega pursued significant facility expansions to support manufacturing and research capacity, including a $100 million project in Fitchburg, Wisconsin, that added a 302,000-square-foot manufacturing building in 2011.^[9] This was followed by further manufacturing growth in Madison in 2018 and the opening of the 280,000-square-foot Kornberg Center in 2021, a sustainable R&D facility designed to reduce energy use by 40% through features like geothermal heating and advanced airflow systems.^[10] These investments aligned with organic growth strategies, as articulated by founder Bill Linton, emphasizing internal development over large-scale mergers.^[11] Revenue approached $400 million by 2016, reflecting steady expansion driven by product demand in biotechnology tools.^[12] Into the 2020s, Promega continued infrastructure scaling with the Kepler Center logistics expansion in 2024, increasing total space to 320,000 square feet for improved supply chain efficiency, and a 2025 lyophilization capacity doubling at its Madison site to enhance reagent stability and production scalability.^[13]^[14] The company acquired a minority stake from shareholders in 2020 via a settlement exceeding $300 million, while Eppendorf AG took a 13.7% equity position, providing capital without altering core control.^[15]^[16] Revenue estimates reached $450–500 million by 2024–2025, supported by a workforce of approximately 1,600 employees.^[17]^[18] Strategic initiatives emphasized sustainability and collaborations, with Promega joining the UN Global Compact in 2010 and committing to 100% renewable electricity globally by 2025, alongside Science Based Targets initiative-aligned goals for 50% greenhouse gas reductions from 2019 levels by 2030.^[19]^[20]^[21] Partnerships accelerated innovation, including joint marketing with INOVIQ for exosome tools in 2023, expanded BioLabs support for biotech startups, and licensing deals like the 2025 Addgene plasmid collection and Watchmaker Genomics reverse transcriptase.^[22]^[23]^[24]^[25] These efforts prioritized empirical advancements in molecular tools over external biases in reporting, focusing on verifiable operational enhancements.

Corporate Structure and Operations

Ownership and Leadership

Promega Corporation is a privately held biotechnology company founded in 1978 by William A. Linton in Madison, Wisconsin.^[1]^[26] As a private entity, it does not trade publicly and has prioritized independence, with Linton maintaining controlling influence through his ownership stake, though exact percentages are not publicly disclosed.^[11]^[15] The company's ownership has faced challenges from minority shareholders, including a 2015 rejected hostile takeover bid at $625 per share and a subsequent 2016 lawsuit alleging shareholder oppression by Linton to preserve private control and potentially transfer shares to the Usona Institute, a nonprofit he founded.^[27]^[28] The dispute settled in 2020 for over $300 million to the plaintiffs, dismissing claims without admission of liability and affirming Promega's private structure.^[15] In August 2020, Eppendorf AG acquired a 13.7% minority stake, marking the first significant external investment while Linton retained operational control.^[16] Leadership is centered on William A. Linton, who has served as Chairman, President, and Chief Executive Officer since founding the company, guiding its growth into a global provider of life sciences tools with over 2,200 employees.^[1]^[29] Linton, a chemist by training from the University of Wisconsin-Madison, emphasizes long-term innovation over short-term financial pressures inherent in public markets.^[30] The executive team includes roles such as Vice President of Human Resources Gayle Paul, supporting operational functions across Promega's international subsidiaries.^[31]

Global Presence and Manufacturing

Promega Corporation maintains its global headquarters in Madison, Wisconsin, United States, where the corporate campus encompasses research, development, and manufacturing operations across multiple specialized facilities. The company operates sales branches in 16 countries and partners with over 50 distributors to reach customers in more than 100 countries. Over 2,000 employees support these operations worldwide, with more than 1,400 based in Madison.^[32]^[23] Manufacturing activities are concentrated at the Madison campus, featuring dedicated centers including the BioPharmaceutical Technology Center for regulated product production, the 159,000-square-foot Chappelle Manufacturing Center for chemical synthesis, the Feynman Center for bioprocessing, and the Rosalind Franklin Center for additional capacity. These sites enabled a tenfold increase in manufacturing output during the COVID-19 pandemic to address global shortages of diagnostic and research reagents. Promega also maintains a manufacturing facility in Shanghai, China, established in 2012 as the Shanghai Promega Life Science Center, which supports regional production and contributes to worldwide supply of biological and chemical products.^[33]^[34]^[35] The company's supply chain emphasizes in-house production of critical reagents, with many suppliers located within 50 miles of Madison facilities to enhance resilience against disruptions. Distribution occurs from hubs in North America, Germany, and Singapore, achieving fill rates exceeding 95% globally and same-day shipping for North American orders received by 4 PM. This infrastructure supports custom manufacturing for original equipment manufacturers, leveraging automated and semi-automated processes for bulk production.^[36]^[37]

Product Portfolio and Technologies

Genomics and Molecular Biology Tools

Promega provides a range of reagents, kits, and enzymes essential for nucleic acid extraction, amplification, cloning, and analysis in genomics and molecular biology applications. These tools support workflows from basic DNA/RNA isolation to advanced PCR-based genotyping and sequencing library preparation, emphasizing high purity and yield for downstream assays.^[38] Key offerings include genomic DNA extraction systems designed for diverse sample types such as blood, cultured cells, tissues, plants, and bacteria, yielding high-molecular-weight DNA suitable for PCR, restriction digestion, and Southern blotting. Notable products encompass the Wizard Genomic DNA Purification Kit for manual processing and automated alternatives like the Maxwell RSC Genomic DNA Kit, which processes up to 48 samples using magnetic particle technology to minimize contamination and hands-on time.^[39]^[40] In PCR and quantitative PCR (qPCR), Promega's GoTaq family of thermostable DNA polymerases and master mixes, including GoTaq Probe qPCR Master Mix available in 100- or 200-reaction formats, enables robust amplification with antibody-mediated hot-start functionality to reduce non-specific products and improve sensitivity in gene expression and SNP detection assays. These reagents incorporate dNTPs, buffers, and optimized MgCl2 for one-step setup, supporting real-time detection with TaqMan probes.^[41]^[42] For cloning and vector manipulation, Promega supplies molecular biology enzymes such as T4 DNA ligase for cohesive and blunt-end ligations, T7, T3, and SP6 RNA polymerases for in vitro transcription of RNA probes or mRNA capping, and restriction enzymes paired with dephosphorylation tools like recombinant alkaline phosphatase to prevent self-ligation. These facilitate plasmid construction, insert verification, and expression vector engineering in bacterial or eukaryotic systems.^[43] Promega also addresses next-generation sequencing (NGS) preparation through purification kits for NGS-ready DNA/RNA, including magnetic bead-based systems that remove contaminants like primers, adapters, and salts while preserving fragment size distribution for accurate library quantitation. Complementary tools for nucleic acid quantitation, such as the QuantiFluor dsDNA System using fluorescent dyes, ensure precise measurement of low-input samples prior to sequencing or array hybridization.^[44]^[45] In September 2025, Promega announced a strategic partnership with Watchmaker Genomics to integrate engineered high-performance enzymes into its genomics portfolio, aiming to enhance fidelity and speed in library preparation and amplification steps for large-scale sequencing projects. This collaboration builds on Promega's established enzyme technologies to address limitations in throughput and error rates observed in standard molecular biology workflows.^[25]

Proteomics and Protein Analysis

Promega provides a range of reagents and systems for proteomics workflows, encompassing protein expression, purification, quantification, and characterization, particularly tailored for mass spectrometry applications.^[46] These tools support researchers in analyzing protein structures, interactions, and modifications through affinity-based purification and enzymatic digestion protocols.^[47] Central to Promega's protein purification offerings are magnetic bead-based systems utilizing affinity tags such as polyhistidine (His-tag), glutathione S-transferase (GST), and HaloTag. The MagneHis™ Protein Purification System enables rapid isolation of His- or HQ-tagged recombinant proteins from cell lysates using nickel-charged magnetic beads, yielding high-purity samples in under one hour without centrifugation.^[48] Similarly, the HaloTag® Protein Purification System leverages a self-labeling protein tag for covalent attachment to chloroalkane ligands on resin, facilitating efficient purification of fusion proteins while enhancing solubility and expression levels in bacterial, mammalian, or cell-free systems.^[49] These systems are compatible with automation, reducing hands-on time and variability in downstream analyses like Western blotting or enzymatic assays.^[50] In mass spectrometry-focused proteomics, Promega supplies sequencing-grade proteases, including trypsin and alternatives like Lys-C, Glu-C, and chymotrypsin, optimized for complete protein digestion and minimal autolysis to improve peptide coverage and identification accuracy.^[51] Complementary sample preparation tools, such as the Magnetic Proteomics Sample Prep (MPSP) Kit, employ SP3 (single-pot, solid-phase-enhanced) methodology with carboxylate-functionalized magnetic beads for detergent-compatible protein enrichment, cleanup, and digestion, enabling reproducible proteome profiling from complex samples like plasma or tissues.^[52] These innovations address challenges in proteome depth by supporting middle-down proteomics and integrating with liquid chromatography-tandem mass spectrometry (LC-MS/MS) for quantitative post-translational modification analysis.^[53] Promega's protein analysis reagents also include fluorescent ligands and pull-down systems for studying protein-protein or protein-nucleic acid interactions, as well as kits for histone mark enrichment in epigenetics-related proteomics.^[54] Overall, these products emphasize scalability from low-throughput research to high-throughput screening, with formulations designed for consistency across diverse biological matrices.^[55]

Drug Discovery and Cellular Assays

Promega's cellular assays for drug discovery leverage bioluminescent technologies to enable high-throughput screening of small molecules and biologics, focusing on cell health, target engagement, and mechanism-of-action studies. These tools support evaluation of compound effects on viability, cytotoxicity, and intracellular signaling, often in physiologically relevant models like 3D cultures and primary cells.^[56]^[57] Cell viability and cytotoxicity assays, such as the CellTiter-Glo® luminescent assay, quantify ATP levels as a proxy for metabolically active cells, allowing detection of drug-induced proliferation or death in endpoint or real-time formats. These assays accommodate diverse cell types, including organoids and stem cells, and are optimized for automation in early-stage toxicity screening. Complementary fluorescent options like CellTiter-Fluor™ provide non-destructive readouts for multiplexing with other endpoints.^[58]^[57] The NanoBRET® Target Engagement platform uses bioluminescence resonance energy transfer (BRET) between NanoLuc® luciferase-fused target proteins and fluorescent tracers to measure live-cell binding affinity, occupancy, and residence time of compounds. This intracellular assay reveals compound permeability and selectivity, identifying fewer off-target hits compared to biochemical methods—for instance, distinguishing 16 specific interactions versus 49 in kinase profiling with crizotinib. Applications include kinase, RAS, and E3 ligase assays, aiding targeted degradation studies with CRISPR-edited lines tagged for real-time monitoring.^[59]^[56] Additional assays target kinase activity, ADME properties, and energy metabolism pathways, using luminescent detection to profile oxidative stress, cytochrome P450 function, and autophagy in disease models like cancer. These facilitate compound optimization by integrating cellular context, reducing attrition in later development stages.^[60]^[61]^[62]

Forensics and Human Identification

Promega provides a range of reagents and instruments for forensic DNA analysis and human identification, focusing on short tandem repeat (STR) profiling via capillary electrophoresis (CE) and support for massively parallel sequencing (MPS). These tools enable genetic fingerprinting from challenging samples, including degraded or inhibited DNA, through processes like DNA extraction, quantitation, amplification, and detection. The company's offerings align with standards such as the CODIS core loci recommended by the FBI, facilitating casework, database building, paternity testing, and relationship analysis.^[63]^[64] Central to Promega's forensics portfolio are the PowerPlex® STR amplification systems, which multiplex multiple loci for efficient genotyping. The PowerPlex® Fusion System, for instance, amplifies 24 STR loci plus an internal performance control in a single reaction, delivering high success rates from forensic and paternity samples. Other variants include the PowerPlex® 21 System for 21 loci in human identification applications, the PowerPlex® Y23 System for 23 Y-STR markers in male lineage analysis, and the 8-dye PowerPlex® 35GY System, which covers 20 CODIS loci, 11 Y-STRs, and quality indicators for enhanced discrimination in complex mixtures or degraded evidence; this system is approved by the U.S. National DNA Index System (NDIS). Complementary products include qPCR-based kits like the Plexor® HY System for human-specific DNA quantitation prior to amplification, and the DNA IQ™ System for automated extraction from diverse sample types such as blood or buccal swabs. For analysis, the Spectrum® CE System supports 8-color chemistry with four-plate capacity and compatibility with existing STR kits, streamlining workflows in high-throughput labs.^[65]^[66] Promega's innovations have advanced forensic capabilities, particularly in overcoming artifacts like stutter peaks that complicate interpretation of PCR-amplified STRs. In September 2024, the company introduced a Reduced Stutter Polymerase enzyme, engineered to virtually eliminate these artifacts, improving accuracy in mixture deconvolution and low-template analysis. Kits like the PowerPlex® 35GY have enabled European labs to resolve cold cases by extracting more informative data from compromised samples, as noted in a May 2024 release. Promega has sponsored the International Symposium on Human Identification (ISHI) since 1990, fostering advancements in the field, and its tools are integrated into automated workflows for sexual assault evidence kits, yielding reliable DNA profiles essential for prosecution.^[67]^[68]^[69]^[70]

Integrated Platforms and Automation

Promega provides a range of automation solutions designed to streamline laboratory workflows, particularly in nucleic acid extraction, purification, and assay preparation, enabling higher throughput and reproducibility while minimizing manual intervention.^[71] These systems integrate proprietary chemistries with compatible instrumentation, supporting applications in genomics, proteomics, forensics, and drug discovery.^[72] Central to Promega's offerings are the Maxwell® instruments, benchtop systems for automated DNA, RNA, or total nucleic acid purification. The Maxwell® RSC Instrument processes up to 1 sample at a time with cartridge-based technology, while the Maxwell® RSC 48 handles up to 48 samples per run, and the Maxwell® FSC supports forensic short tandem repeat (STR) analysis with specialized protocols.^[73] These platforms feature walk-away operation, reducing hands-on time to under 5 minutes per run and yielding high-quality extracts suitable for downstream PCR, qPCR, or sequencing without phenol-chloroform extraction.^[73] For high-throughput needs, Promega's ReliaPrep™ and Maxwell® chemistries integrate with robotic platforms such as Tecan Freedom EVO, Thermo Fisher KingFisher, or Beckman Coulter systems, processing hundreds of samples daily from diverse matrices like blood, tissue, or swabs.^[74] These solutions emphasize scalability, with protocols optimized for 96- or 384-well formats, and include free expert support for method transfer and troubleshooting to ensure compatibility across user-defined automation setups.^[74] Promega also facilitates liquid handler-based assay automation, adapting bioluminescent or purification assays for integration on platforms like Hamilton or Agilent systems, which supports flexible reagent dispensing, sample management, and endpoint detection.^[75] This approach allows customization for specific workflows, such as viral RNA extraction during high-demand scenarios, enhancing efficiency without requiring proprietary hardware.^[75] Overall, these integrated tools address common automation challenges like instrument downtime by recommending modular setups over monolithic systems.^[76]

Innovations and Scientific Impact

Key Technological Advancements

Promega pioneered the RNasin® RNase Inhibitor in the 1980s, a recombinant protein that inhibits ribonuclease activity to preserve RNA integrity during extraction and reverse transcription, enabling reliable molecular biology workflows and later proving essential for SARS-CoV-2 vaccine development.^[1] In the 1990s, the company acquired bioluminescent sensor technology based on luciferase enzymes, providing a non-radioactive alternative for detecting biological processes with high sensitivity; this foundation supported assays like the Dual-Luciferase® Reporter Assay for gene expression analysis and CellTiter-Glo® for cell viability, reducing hazards while improving throughput in drug screening and toxicology studies.^[1]^[77] Advancements in engineered luciferases marked subsequent innovations, including the NanoLuc® luciferase introduced in 2012, a compact 19 kDa enzyme 150-fold brighter than firefly luciferase, facilitating real-time imaging and protein interaction studies; it earned recognition as a Top 10 Innovation by The Scientist magazine for its versatility in live-cell applications.^[78] Building on this, the NanoBiT™ structural complementation system (2015) splits NanoLuc® into subunits for detecting protein-protein interactions via reassembly and luminescence, offering superior dynamic range over traditional methods like fluorescence resonance energy transfer (FRET).^[79] Similarly, the HiBiT® Protein Tagging System (2017), using an 11-amino-acid peptide tag that complements NanoLuc® for quantitative protein detection, was named a Top 10 Innovation, enhancing proteomics by enabling nanogram-level sensitivity in high-throughput formats without genetic fusion disruptions.^[80] In cellular assay development, Promega's NanoBRET® Target Engagement platform, launched in the 2010s, integrates bioluminescence resonance energy transfer (BRET) for intracellular monitoring of compound-target binding kinetics, with the NanoBRET® TE Intracellular Kinase Assay receiving the SelectScience Reviewers’ Choice Award for advancing drug discovery precision.^[1] Forensic tools advanced with the DNA IQ™ System in the 2000s, automating DNA extraction from diverse samples for human identification, applied in identifying 9/11 victims and recognized as a Top 100 Technology by R&D Magazine in 2002.^[1] More recently, a 2019 CRISPR licensing agreement enabled genome-editing reagents for research, while the 2024 GloMax® Galaxy imager supports NanoLuc®-based microscopy for non-invasive protein dynamics visualization in live cells.^[81]^[82] These developments underscore Promega's emphasis on bioluminescent and nucleic acid technologies, prioritizing sensitivity, safety, and scalability over legacy radioactive or fluorescent alternatives.

Contributions to Research and Applications

Promega's bioluminescent assay technologies, including luciferase-based systems, have enabled precise measurement of kinase activity and ATP levels in high-throughput drug discovery, serving as alternatives to traditional ATP-depletion methods with superior sensitivity and dynamic range.^[83] These tools have supported selectivity profiling of kinase inhibitors, accelerating the identification of therapeutic candidates in oncology and other fields.^[84] In protein interaction studies, the NanoLuc luciferase has provided brighter signals and smaller size for in vivo imaging and proximity assays, facilitating research into protein stability and dynamics.^[85] In forensics and human identification, Promega's PowerPlex systems, such as the PowerPlex 21 kit, have expanded STR loci coverage to 21 markers, enhancing discrimination power for forensic DNA analysis and paternity testing while maintaining compatibility with existing databases.^[86] These kits have been validated across diverse populations, contributing to reliable casework in criminal investigations and missing persons identification.^[86] Promega technologies have advanced targeted protein degradation and cellular assays, with NanoBRET target engagement tools enabling real-time monitoring of drug-protein interactions in live cells, thus bridging biochemical and functional readouts in small molecule and biologics development.^[87] Company-supported research has applied these in oncology, demonstrating selective degraders effective against multiple myeloma cells, and in reproductive biology, where STK33 inhibition via Promega-provided assays revealed reversible contraception mechanisms in murine models.^[88]^[89] Additionally, their nucleic acid purification kits have supported environmental surveillance, such as direct capture of viral RNA from wastewater for epidemiological tracking.^[90] These applications underscore Promega's role in enabling scalable, reproducible workflows across basic research and applied sciences.

Sustainability and Responsibility

Environmental Management

Promega Corporation integrates environmental management into its core operations through a structured Corporate Responsibility program, emphasizing reductions in resource use and emissions across manufacturing, product design, and facilities. The company employs green chemistry principles in product development to minimize hazardous materials and waste, alongside redesigned packaging that uses less paperboard, ink, and adhesive to lower material consumption. Sustainable shipping options, including consolidated shipments and carbon credit offsets exceeding 900 tons of CO2 for logistics, further mitigate impacts.^[91]^[92] In May 2025, Promega's Madison, Wisconsin headquarters achieved ISO 14001:2015 certification for its environmental management system, covering waste reduction, regulatory compliance, and ongoing impact minimization. This certification underscores a commitment to continual improvement, aligning with broader strategies like employee-led recycling programs and facilities designed for energy efficiency. The standard supports Promega's goal of 100% renewable electricity sourcing by the end of 2025, building on 75% renewable usage reported in 2024.^[93]^[94] Promega's 2030 sustainability goals, established in 2021 and indexed to revenue from a 2019 baseline, target a 50% reduction in greenhouse gas emissions (equivalent to removing 4,800 cars from roads), alongside 30% cuts in landfill waste and water usage. Progress includes a 48% emissions decline since 2019, achieved through renewable energy adoption—such as the largest solar array in Dane County, Wisconsin—and efficiency projects in water conservation and waste minimization. In July 2025, the company committed to the Science Based Targets initiative (SBTi), pledging near-term, science-aligned GHG reduction targets developed collaboratively across sustainability, manufacturing, and engineering teams.^[95]^[96]^[97] Additional initiatives focus on sustainable construction for new facilities, global recycling expansion for lab plastics and electronics, and product innovations that reduce environmental footprints in research applications, such as alternatives to animal testing and biodiversity tools. These efforts reflect a science-driven approach to stewardship, with annual Corporate Responsibility Reports tracking metrics against UN Sustainable Development Goals.^[91]^[92]^[98] Promega maintains a framework of ethical guidelines through multiple codes of conduct, including the Promega Code of Conduct, Channel Partner Code of Conduct, and Supplier Code of Conduct, which mandate compliance with laws, honest decision-making, and zero tolerance for corruption or bribery.^[99] The company also enforces a Policy on Interactions with Healthcare Providers to regulate engagements with professionals in the sector.^[99] Additionally, Promega's Human Rights and Labor Policy addresses ethical operations in biotechnology, emphasizing dignity and fair treatment across its global workforce of over 2,000 employees in 16 locations.^[99] As a signatory to the United Nations Global Compact since 2010, Promega aligns its practices with principles on human rights, labor standards, environmental stewardship, and anti-corruption, integrating these into business operations without reported violations.^[99] The company practices equal opportunity and affirmative action, fostering diversity in a culturally varied workforce.^[100] In employee relations, Promega prioritizes wellbeing, earning recognition as a BioSpace 2024 Best Place to Work and Top Workplaces USA and Regional (Madison, WI) awards in 2022 and 2023 based on employee feedback surveys.^[94] For community engagement, Promega supports education and social initiatives, including the BioPharmaceutical Technology Center Institute (BTC Institute), which has educated over 100,000 students and professionals since its founding more than 30 years ago through programs in biotechnology and related fields.^[101] It funds over 40 U.S. biotechnology startup incubators via donations and provides scholarships like the D.O.O.R.S. program, which in recent years supported 10 students from underrepresented backgrounds with financial aid and mentoring by company scientists.^[94] Other efforts include the Promega Art Showcase, a quarterly public exhibit on its Madison campus for over 25 years featuring local and international artists, and the Woods Hollow Children’s Center, established in 1991 to offer early childhood education to employees' and community members' children aged 6 weeks to 10 years.^[101]

Reception and Challenges

Achievements and Industry Recognition

Promega Corporation has garnered recognition for several product innovations through R&D Magazine's awards program. In 1998, its GenePrint PowerPlex 1.1 System for DNA typing received a Top 100 Innovative Products award, highlighting advancements in forensic analysis capabilities. The DNA IQ System earned a Top 100 Technology designation in 2002 for streamlining automated DNA extraction in high-throughput applications.^[1] Similarly, the P450-Glo CYP450 Assay System was named among the top technologies in 2004 for enabling luminescent detection of cytochrome P450 activity in drug metabolism studies.^[2] Further accolades include The Scientist magazine's 2012 Top 10 Innovations award for NanoLuc luciferase, a small, bright enzyme that expanded applications in reporter gene assays and biosensors.^[2] The NanoBRET TE Intracellular Kinase Assay received a SelectScience Reviewers' Choice Award in the 2010s for facilitating real-time monitoring of kinase activity in live cells, aiding drug discovery efforts.^[1] In manufacturing standards, Promega achieved a milestone in 2015 as the first company to secure third-party certification under ISO 18385, verifying processes that minimize human DNA contamination—essential for sensitive forensic and genetic research workflows.^[2] The company obtained ISO 13485 certification in 2005 for its quality management systems in medical device production.^[2] More recently, its Madison headquarters earned ISO 14001:2015 certification in May 2025 for environmental management, demonstrating systematic approaches to compliance and pollution prevention.^[93] Promega's sustainability initiatives have also received external validation, including a Gold Medal rating from EcoVadis for its UK operations, reflecting strong performance in environmental, social, and ethical practices relative to industry peers.^[102] In economic impact, the company won the Wisconsin Economic Development Association's Business Retention and Expansion award in 2019 for its research and development facility expansion, which supported job growth and regional biotechnology development.^[103]

Criticisms and Operational Critiques

In 2017, minority shareholders initiated a lawsuit against Promega Corporation and its founder and CEO B.L. Linton, asserting claims of shareholder oppression under Wisconsin's corporate dissolution statute.^[104] The suit alleged malfeasance, including a 2014 share buyback proposal intended to consolidate majority control at the expense of minority interests by undervaluing shares and limiting dissenters' rights.^[105] Promega and Linton contested these accusations, maintaining that the buyback and related governance decisions prioritized long-term company stability and were not oppressive.^[104] The litigation proceeded to a month-long bench trial in 2020, culminating in a settlement exceeding $300 million awarded to the minority shareholders through representation by the law firm Susman Godfrey.^[15] The court dismissed the case following the agreement, with no admission of liability by Promega.^[106] This resolution highlighted tensions in the closely held structure of the privately owned firm, where a small group of longtime investors sought valuation and exit remedies amid disputes over equity dilution risks.^[106] Promega has also engaged in multiple patent infringement disputes, both as plaintiff and defendant, such as the 2025 lawsuit against Aobious over NanoLuc luciferase technology components and earlier conflicts with Roche over Taq polymerase rights dating to 1992.^[107]^[108] These cases, while resulting in injunctions, settlements, or Supreme Court reversals (e.g., Life Technologies Corp. v. Promega Corp. in 2017 limiting extraterritorial liability), reflect standard competitive pressures in biotechnology rather than unique operational deficiencies.^[109] Employee feedback indicates mixed operational experiences, with Indeed aggregating a 3.7/5 rating across 43 reviews citing adequate benefits but occasional concerns over work-life balance and management consistency in a fast-paced research environment.^[110] No systemic ethical scandals or environmental critiques have emerged in public records, though the firm's private status limits transparency on internal governance.^[110]

References

[1]
Promega Company Information | About Promega
History ; Bill Linton, Promega founder in 1978. 1978 ; rnasin rnase inhibitor. 1980s ; Bioluminescence technology by Promega. 1990s ; DNA IQ kit. 2000s ; NanoBRET TE ...
[2]
History of Curiosity - Promega Corporation
1978 Bill Linton founds Biotec, later named Promega. His vision was to create a place where biotechnology would lead to the cure and prevention of disease.
[3]
Custom Manufacturing for Biopharma and Biotechnology
Our focus is providing custom solutions tailored to maximizing efficiency and optimizing workflows in your biopharmaceutical or biotechnology laboratory.
[4]
Promega, Aobious Resolve Patent Infringement Lawsuit
Aug 5, 2025 · Promega settled a lawsuit with Aobious over luciferase substrate patents. The court confirmed infringement, issued a permanent injunction, ...Missing: achievements controversies
[5]
William Linton - Wisconsin 275 Most Influential Business Leaders
Linton founded the company in 1978 to provide restriction enzymes to molecular biologists. In 1984, the company launched a joint venture to set up China's ...Missing: history | Show results with:history
[6]
Capitalist with a soul - Isthmus | Madison, Wisconsin
Sep 5, 2013 · This was the genius of Bill Linton's plan for Promega, which he founded in 1978 at about the time biotechnology was exploding. He sold picks ...Missing: history | Show results with:history
[7]
Promega History: Founding, Timeline, and Milestones - Zippia
Promega Corporation was founded by Bill Linton in 1978 to provide restriction enzymes for biotechnology. 1985. Promega Corporation also established the first ...
[8]
About Us - Promega Corporation
Promega AG was established as Catalys AG in 1991 as the Swiss branch office of Promega Corp., a Madison (Wisconsin, USA) based, innovative manufacturer and ...
[9]
Promega expansion now totals $100M | LOCAL NEWS - Fitchburg Star
Aug 24, 2011 · The company plans to build a 302,000 square foot manufacturing facility on the company's current campus on Woods Hollow Road near East Sheryl ...
[10]
Promega Opens New Research & Development Facility Supporting ...
Apr 6, 2021 · The new 280,000 sq ft Kornberg Center supports life science research, has advanced labs, and integrates sustainable practices, reducing energy ...Missing: expansions 2010s 2020s
[11]
Promega Corporation Founder and CEO Faces Off With ... - BioSpace
To say that Bill Linton has a long-term vision for Promega, the Fitchburg, WI-based biotech business he founded in 1978 and ...
[12]
[PDF] Company Facts & Figures - Promega Corporation
Promega BioSystems Sunnyvale, Inc. Sunnyvale, CA, USA. Shanghai Promega Biological Products, Ltd. Shanghai, China. Over 50 Global Distributors. Founded. 1978.Missing: history | Show results with:history
[13]
Logistics Built to Deliver: Kepler Center and Beyond
Jun 25, 2024 · This massive expansion has increased the facility's total area to an astounding 320,000 square feet (29,822 square meters). So, what does this ...Missing: 2020s | Show results with:2020s
[14]
Promega Expands Lyophilization to Meet Tomorrow's Demands
May 7, 2025 · The new lyophilization equipment will more than double the lyophilization capacity of Promega Madison. On March 12, 2025, a 46,000-pound ...
[15]
Susman Godfrey Secures More than $300 Million for Minority ...
Oct 9, 2020 · Promega acquired Susman Godfrey's clients' Promega shares for more than $300 million—a huge premium over the pre-suit redemption price and ...
[16]
[PDF] 75 Years & Beyond - Eppendorf Corporate
May 5, 2021 · Furthermore, in August 2020, Eppendorf acquired a 13.7% stake in the U.S. life science company Promega Corporation. This highly innovative ...
[17]
Promega Revenue, Growth & Competitor Profile - IncFact
Aug 4, 2025 · The Premium Promega Company Report contains critical information including: Revenue from previous years (2020 to present); Growth rate ...
[18]
Promega Revenue: Annual, Quarterly, and Historic - Zippia
Promega has 1,601 employees, and the revenue per employee ratio is $281,074. Promega peak revenue was $450.0M in 2024.Missing: growth 2010-2025
[19]
Company - Promega Corporation
Promega has been a member of the UN Global Compact since 2010 and considers the United Nation Sustainable Development Goals (SDGs) in where and how we act.Missing: growth milestones
[20]
Promega Commits to 100% Renewable Electricity by 2025
Jun 13, 2023 · Promega Corporation has committed to sourcing 100% of its global electricity usage from renewable sources by 2025.
[21]
Promega Exceeds 2020 Energy Goals, Sets New Targets
Promega Corporation recently released its 2030 environmental goals, including a target to reduce emissions 50% from a 2019 baseline.<|separator|>
[22]
INOVIQ and Promega announce global joint marketing agreement ...
Jul 6, 2023 · INOVIQ and Promega announce global joint marketing agreement for EXO-NET exosome isolation and nucleic acid purification solutions.Missing: expansions acquisitions 2010s 2020s
[23]
BioLabs and Promega announce collaboration to support young ...
Dec 13, 2023 · BioLabs and Promega today announced the expansion of their collaborative efforts to accelerate life science innovation worldwide through ...Missing: acquisitions 2010s 2020s
[24]
Addgene Announces Strategic Partnership with Promega to Launch ...
Jul 15, 2025 · Addgene has announced a strategic partnership with Promega to launch the Promega Plasmid Collection, significantly expanding Addgene's ...Missing: initiatives modern
[25]
Promega and Watchmaker Genomics Announce Strategic ...
Sep 9, 2025 · Promega has entered a strategic partnership with Watchmaker Genomics to license a novel engineered reverse transcriptase.Missing: 2010- present<|separator|>
[26]
Promega 2025 Company Profile: Valuation, Funding & Investors
When was Promega founded? Promega was founded in 1978. ; Where is Promega headquartered? Promega is headquartered in Madison, WI. ; What is the size of Promega?
[27]
Promega board turns down hostile takeover attempt
Oct 29, 2015 · The new board of directors at Promega Corp. is rejecting a hostile takeover attempt by two shareholders seeking to purchase the company and ...
[28]
Promega Settles Lawsuit with Minority Shareholders
Nov 30, 2020 · We talked about the lawsuit between Promega Corp., a biotech company based in Madison, Wisconsin, and its shareholders a couple months ago in this blog post.<|control11|><|separator|>
[29]
Bruker Corporation - Board of Directors - Person Details
Since 1978, Dr. Linton has served as the Chairman, President and Chief Executive Officer of Promega Corporation in Madison, Wisconsin, a privately held life ...
[30]
Bill Linton - Usona Institute
Linton founded Promega Corporation in 1978 and has served continuously as its President and Chief Executive Officer. A global life science research company, ...
[31]
Promega Corporation Management Team | Org Chart - RocketReach
The Promega Corporation management team includes William Linton (CEO and Chairman), Gayle Paul (Vice President, Human Resources), and Anne Readel (Deputy ...
[32]
Promega Named a BioSpace 2025 Best Places to Work Winner
Nov 13, 2024 · Promega employs more than 2,000 people worldwide, with more than 1,400 reporting to its Madison, WI location. The Promega employee base ...Missing: facilities | Show results with:facilities
[33]
Promega Corporation - Chappelle Manufacturing Center
Named in honor of a leader in bioluminescence research, the new, 159,000-square-foot Chappelle Manufacturing Center (CMC) offers multifaceted chemical ...Missing: presence | Show results with:presence
[34]
Promega Corporation's Manufacturing Facility, Wisconsin
Oct 31, 2013 · The branches of the company are located across 16 countries worldwide. The company also has more than 50 international distributors spread ...Missing: global presence
[35]
Promega Opens New Shanghai Facility - Fierce Pharma
Nov 15, 2012 · The new facility, called Shanghai Promega Life Science Center, is one of five Promega manufacturing sites worldwide. Together these facilities ...Missing: presence | Show results with:presence
[36]
Global Supply Logistics - Promega Corporation
Many of our suppliers are located within 50 miles of our manufacturing facilities. ... Manufacturing Capabilities with Global Reach. Are you looking for a ...Missing: presence | Show results with:presence
[37]
OEM Manufacturing | Custom Reagents - Promega Corporation
Our extensive manufacturing infrastructure and global distribution network allow flexible bulk manufacture, with capabilities for custom, automated or semi- ...Products and Technologies · Service · Quality · Markets Served
[38]
Nucleic Acid Analysis - Promega Corporation
Products and educational resources for genomic analysis including nucleic acid extraction and quantitation, PCR, sequencing, and basic cloning.
[39]
DNA Extraction | Genomic DNA Isolation - Promega Corporation
Promega genomic DNA extraction products are designed for isolation of high-quality DNA from many sample types, including blood, cells, tissues, plants, ...
[40]
Promega Product Listing
Explore our assays and instruments that support researchers in the fields of cell biology, drug discovery, human identification, clinical research and more.Cloning and DNA Markers · Cell Health Assays · Products · Nucleic Acid Extraction
[41]
Genomics Essentials - Get more out of your budget - Promega
A6100, GoTaq ® Probe qPCR Master Mix, 100 reactions, 56,00 € ; A6101, GoTaq ® Probe qPCR Master Mix, 200 reactions, 99,00 € ; A6102, GoTaq ® Probe qPCR Master Mix ...
[42]
Genomics Essentials - Promega Corporation
Indispensable tools for discerning molecular biologists, featuring thermostable phosphatases, DNA polymerases, RNA polymerases, ligases, kinases, and nucleases.
[43]
Molecular Biology Enzymes | Ligases | RNA Polymerases
Promega offers a variety of cloning enzymes including DNA and RNA ligases and polymerases. T7, T3, and SP6 RNA Polymerases are popular choices for in vitro ...
[44]
NGS Reagents | Next-Gen Sequencing - Promega Corporation
Manual and automated purification systems to produce the highest quality, NGS-ready DNA. Quantitation for NGS. Tools for accurate DNA and RNA quantitation, and ...
[45]
Calculators and Tools | Data Analysis - Promega Corporation
Online tools and mobile apps for performing common molecular biology calculations, analyzing data and more. Includes transfection optimization, helpful kinase ...Missing: genomics | Show results with:genomics
[46]
Tools for Protein Analysis: A Proteomics Product Guide
The Proteomics Guide provides a comprehensive overview of products and technologies used for protein expression, purification, analysis and characterization.
[47]
Protein Analysis - Promega Corporation
Promega's unique portfolio of protein analysis laboratory products include mass spec proteases, protein purification tags/resins and fluorescent ligands, cell- ...
[48]
MagneHis™ Protein Purification System - Promega Corporation
The MagneHis™ Protein Purification System provides a magnetic-based, rapid method for the purification of polyhistidine- or HQ-tagged, expressed proteins.
[49]
HaloTag® Protein Purification System - Promega Corporation
HaloTag® Protein Purification System is designed to purify proteins fused to the HaloTag® novel protein tag that enhances expression and solubility of ...
[50]
An Introduction to Protein Purification Methods - Promega Corporation
A guide to protein purification technologies, including affinity purification tags such as GST, His-tag, HaloTag and biotin, as well as pull-down systems.Protein Purification Strategies · Affinity Tags for Protein... · Purification of HaloTag...
[51]
Mass Spectrometry - Promega Corporation
Promega provides high-quality proteases, including trypsin and alternative proteases specifically developed for mass spectrometry applications.
[52]
Magnetic Proteomics Sample Prep (MPSP) Kit - Promega Corporation
Magnetic beads for streamlined, SP3-based proteomics sample preparation.
[53]
Protease Digestion for Mass Spectrometry | Protein Digest Protocols
Promega offers various alternative proteases that complement trypsin and allow efficient protein analysis with mass spectrometry. Figure 5 highlights the ...
[54]
Protein Analysis and Complex Purification - Promega Corporation
Promega offers protein purification and interaction products for epigenetics research to analyze histone marks and identify protein binding partners rapidly ...Missing: proteomics | Show results with:proteomics
[55]
Protein Purification - Promega Corporation
We offer a range of protein purification kits and reagents for purification of recombinant proteins using affinity tags such as HaloTag, GST- or His-tag.
[56]
Small Molecule Drug Discovery - Promega Corporation
A comprehensive collection of CRISPR-edited cell lines and clones with popular targets fused to a small bioluminescent tag, supports these live-cell assays. In ...Solutions · Conferences
[57]
Cell Health Assays - Promega Corporation
Cell health assays are used to detect and monitor various cellular events and build a picture of how and why cells live or die.
[58]
Cell Viability Assays | Cytotoxicity Assays | Cell Death Detection
Promega offers a range of viability assays that use colorimetric, fluorescent or bioluminescent detection, based on the reducing potential of viable cells.CellTiter-Glo® Luminescent... · CellTiter-Fluor™ Cell Viability... · CellTiter-Glo® 2.0
[59]
NanoBRET® Target Engagement | Live-Cell Compound Binding ...
Promega has developed a novel live-cell binding assay, called the NanoBRET® Target Engagement Assay. It uses an energy transfer technique known as ...
[60]
Kinase Biology for Drug Discovery - Promega Corporation
We offer a large portfolio of ready-to-use bioluminescent biochemical and cellular kinase assays that can measure a compound's effect on kinase activity.
[61]
Drug Discovery: ADME/Toxicity - Promega Corporation
A critical stage in the drug discovery process is studying the absorption, distribution, metabolism and excretion (ADME) of drug candidates.
[62]
Interrogating Energy Metabolism Pathways for Drug Discovery
This schematic diagram shows high-throughput assays that can be used to interrogate key energy metabolism pathways that are disrupted in disease states.
[63]
Human Identification Products and Resources | Genetic Identity
Human identification uses CE and MPS to create a genetic fingerprint. Promega offers products for DNA extraction, STR amplification, and analysis, and support ...
[64]
Capillary Electrophoresis (CE) for Forensic DNA Analysis
Capillary electrophoresis (CE) separates amplified DNA by size, creating a DNA profile for forensic analysis. Promega provides solutions for CE analysis.
[65]
PowerPlex® Fusion System - Promega Corporation
The PowerPlex® Fusion System delivers more information and high success rates from demanding forensic, paternity and relationship-testing cases. Using proven ...
[66]
PowerPlex® 21 System - Promega Corporation
The PowerPlex® 21 System is a multiplex STR system for human identification applications including forensic analysis, relationship testing and research use.
[67]
Promega Engineers New Enzyme to Significantly Reduce Stutter in ...
Sep 25, 2024 · A novel enzyme developed by research scientists at Promega Corporation will virtually eliminate confounding stutter artifacts in forensic DNA ...
[68]
Novel Promega Enzyme Tackles Biggest Challenge in DNA Forensics
Nov 7, 2024 · Known as “Reduced Stutter Polymerase,” the new enzyme virtually eliminates confounding stutter artifacts in forensic DNA analysis. When ...
[69]
Promega Kit Enables European Forensic Labs to Solve Challenging ...
May 7, 2024 · Eight-color kit provides more usable information from degraded or inhibited DNA samples • Includes all DNA markers recommended by the ...<|separator|>
[70]
36th International Symposium on Human Identification (ISHI ...
Aug 19, 2025 · Promega Corporation, a developer and manufacturer of products for DNA-based human identification, has sponsored ISHI since its inception. The ...
[71]
Lab Automation | Automated Sample Prep - Promega Corporation
We offer instruments, chemistries and personalized support that simplify the process of automating sample prep in your lab.
[72]
Lab Automation Resource Center - Promega Corporation
Find the Lab Automation Resources You Need. Explore our collection of How-to Guides to learn how to get started with building an automated workflow and which ...
[73]
Automated DNA Extraction | Maxwell Instruments
Maxwell® Instruments offer benchtop automation with worry-free, walk-away purification of DNA, RNA or total nucleic acid. Choose from instruments that can ...Maxwell® RSC Instrument · Maxwell® RSC 48 Instrument · Maxwell® FSC
[74]
High-Throughput Automated DNA and RNA Extraction
Consistently extract high-quality DNA/RNA from any sample type, on any robot platform and for any downstream application.Automation Platforms · Sample Types · Free Support
[75]
Liquid Handler Assay Automation - Promega Corporation
Work with our scientists who have collaborated with robotic manufacturers to integrate purification technologies on your liquid-handling platforms. flexible ...
[76]
Selecting Lab Automation Instruments - Promega Corporation
Many labs purchase two smaller automated platforms rather than one larger platform to have redundancy and avoid delays in case one instrument is down for ...
[77]
Celebrating 30 Years of "Glo-ing" Research - Promega Connections
Jan 25, 2021 · In December of 1990, Promega first discussed the use of firefly luciferase (luc) as an emerging reporter technology in the article, ...Missing: 2000s | Show results with:2000s
[78]
Promega Corporation Release: NanoLuc™ Luciferase Technology ...
Dec 17, 2012 · Promega Corporation Release: NanoLuc™ Luciferase Technology Named to The Scientist Top 10 Innovations for 2012. December 17, 2012 |. 1 min read.
[79]
https://www.promegaconnections.com/nanobit-assay-transformational-technology-for-studying-protein-interactions-named-a-top-10-innovation-of-2015/
[80]
Promega HiBiT Protein Tagging System Named a 2017 Top 10 ...
Dec 1, 2017 · Promega Corporation announced today that its HiBiT Protein Tagging System has been listed as a 2017 Top 10 Innovation by life science publication The Scientist.
[81]
2019-12-19 CRISPR license to Promega
Dec 19, 2019 · Promega will use MilliporeSigma's CRISPR genome-editing technology to create research products and services, including those for drug ...<|separator|>
[82]
Promega Unveils GloMax® Galaxy Bioluminescence Imager for ...
Oct 1, 2024 · New microscope enables researchers to use NanoLuc® Luciferase to observe protein dynamics and cellular physiology in live cells, ...
[83]
Comparison of Bioluminescent Kinase Assays Using Substrate ... - NIH
We conclude that the bioluminescence ADP detection assay system is a viable generic alternative to the widely used ATP-depletion assay for ATPases.
[84]
Using Bioluminescent Kinase Profiling Strips to Identify ... - PubMed
The luminescent ADP-Glo kinase assay is a universal platform that measures kinase activity by quantifying the amount of the common kinase reaction product ADP.Missing: major | Show results with:major
[85]
NanoLuc: A Small Luciferase is Brightening up the Field of ...
NanoLuc (NLuc), a novel bioluminescence platform, offers several advantages over established systems, including enhanced stability, smaller size, and >150-fold ...
[86]
Functional validation of human-specific PowerPlex® 21 System ...
Oct 3, 2018 · The PowerPlex® 21 System is used for human identification applications including forensic analysis, relationship testing and research use.Missing: major | Show results with:major
[87]
Advancing Therapeutic Insights: The Impact of NanoBRET® Target ...
The NanoBRET® TE assay provides an innovative approach to the drug discovery process, merging the strengths of both functional cellular and biochemical assays.
[88]
Promega Research Shows Potential of Selective Degrader Against ...
Jan 16, 2024 · Promega research published today in Nature Communications demonstrates a new potential approach for managing multiple myeloma and other ...
[89]
Promega Contributes to New Study on Reversible, Non-Hormonal ...
Jun 4, 2024 · Their results show that STK33 inhibition produces a reversible contraceptive effect in mice, making the protein a promising sperm-specific ...
[90]
A direct capture method for purification and detection of viral nucleic ...
Total nucleic acid (TNA) was purified from collected wastewater using the Wizard® Enviro Wastewater TNA kit (Promega Corp.)Missing: major | Show results with:major
[91]
Supporting Sustainability - Promega Corporation
Promega places great emphasis on preserving the environment, investing in sustainable construction of new buildings and striving to steadily reduce CO2 ...
[92]
Sustainability - Promega Corporation
Promega reduces the environmental impacts of our product lifecycle by integrating green chemistry as well as sustainable packaging and shipping options.
[93]
Promega Madison Achieves ISO 14001 Certification for ...
May 6, 2025 · The standard helps businesses reduce waste, comply with regulations and minimize their environmental impact while enhancing sustainability ...
[94]
Promega Highlights Progress in Sustainability, Employee Wellbeing ...
May 22, 2024 · “From increases in renewable energy to employee volunteer programs, we're excited to share the positive changes happening across all Promega ...
[95]
2030 Sustainability Goals: Our Most Ambitious Ever
Aug 2, 2021 · The Promega Corporate Responsibility Program is setting goals that are challenging but attainable for reducing our environmental impact.
[96]
Reducing emissions. Increasing accountability. Promega has ...
Aug 27, 2025 · Promega has reduced its global carbon emissions by 48% since 2019 (indexed to revenue), staying on track for our 2030 goal of a 50% reduction.
[97]
Promega Corporation Commits to Science Based Targets Initiative ...
Jul 30, 2025 · Sustainability is integrated into daily decision-making and long-range planning. As a science-based company, Promega approaches climate action ...
[98]
Promega's Corporate Responsibility Journey
Jun 10, 2022 · Our operations team deserves a lot of credit for implementing energy efficiency, water conservation, and waste minimization projects that reduce ...
[99]
Company
### Summary of Promega's Codes of Conduct, Ethical Business Practices, Interactions with Healthcare Providers, and Ethical Guidelines for Biotechnology Operations
[100]
[PDF] View Corporate Responsibility Report
Promega believes in and practices equal opportunity and affirmative action. As a global company, we acknowledge and honor the fundamental value and dignity ...
[101]
Communities - Promega Corporation
Over its 30 year history, BTC Institute has served more than 100,000 students from upper elementary to college and graduate school, as well as teachers and ...
[102]
Promega UK Awarded Gold Medal by EcoVadis for Sustainability ...
This recognition demonstrates our commitment to sustainability and our efforts to lead by example in the life sciences industry. Our team has worked diligently ...
[103]
Promega awarded CEDA award for economic contributions - WMTV
Sep 12, 2019 · Promega Corporation won the Business Retention and Expansion award from the Wisconsin Economic Development Association for their new research and development ...
[104]
Promega Corporation, CEO Linton Return Fire in Legal Battle with ...
Oct 12, 2017 · A little over a year after a group of shareholders of the life sciences supplies business Promega sued the company, alleging malfeasance by founder and CEO ...Missing: ownership stake
[105]
How We Won: Houston Lawyers' Strategy Leads to $300 Million ...
Sep 11, 2020 · The shareholders alleged that Promega tried to do a large share buyback in 2014 so that the company could get a controlling interest of shares ...
[106]
Shareholder suit against Promega, founder dismissed after settlement
Aug 19, 2020 · Promega, together with Eppendorf AG, a life science instrument manufacturer based in Hamburg, Germany, have acquired the ownership interest ...<|separator|>
[107]
Promega Files Patent Infringement Lawsuit Against Aobious to ...
Mar 5, 2025 · Promega Corporation has filed a patent infringement lawsuit against Aobious, Inc. regarding a key component of NanoLuc® luciferase technology.Missing: biotechnology concerns
[108]
Promega changes tack in battle over patent - Nature
Nov 27, 2003 · Promega of Madison, Wisconsin, has filed a lawsuit against the Swiss pharmaceutical giant Hoffmann-La Roche, which holds a patent on the Taq ...Missing: achievements | Show results with:achievements
[109]
Supreme Court Reverses Life Technologies Corp v. Promega Corp.
Feb 22, 2017 · When Life Technologies began selling the kits outside the licensed fields of use, Promega sued, claiming that patent infringement liability was ...
[110]
Working at Promega Corporation: Employee Reviews | Indeed.com
Rating 3.7 (43) Reviews from Promega Corporation employees about Promega Corporation culture, salaries, benefits, work-life balance, management, job security, and more.