Fact-checked by Grok 2 weeks ago

Repurposing

Repurposing is the adaptation of an object, material, or structure for a function distinct from its original design, typically to extend utility and avert disposal. This approach preserves the item's inherent form, contrasting with recycling's breakdown into raw components for remanufacture. Historically, repurposing emerged from necessity in resource-scarce ancient societies, where structures and artifacts were routinely readapted rather than discarded. Practices persisted through eras of thrift, such as 19th-century fabric alterations and wartime material conversions, predating modern sustainability frameworks. In contemporary applications, repurposing supports circular economies by diminishing reliance on new raw materials extraction and curbing landfill accumulation, with environmental gains including lower energy demands than primary production or even recycling processes. Empirical assessments affirm reuse hierarchies prioritize such methods for their direct reduction in material throughput and emissions avoidance. Industrial examples encompass packaging repurposed into consumer goods, surplus equipment redeployed in manufacturing, and building adaptive reuse that retains embodied carbon while enabling novel occupancy. Defining characteristics include creative ingenuity in function shifts, as seen in household innovations like discarded skis forming outdoor seating or industrial helmets converted to utensils, underscoring repurposing's role in fostering resilience against waste proliferation without necessitating advanced processing.

Definition and Conceptual Foundations

Core Definition

Repurposing refers to the of an object, material, structure, or idea from its original intended function to a new and distinct use, typically involving minimal or targeted modifications rather than complete breakdown or . This process preserves the item's essential form while redirecting its utility, as seen in converting shipping containers into habitable dwellings or from one format to another for broader accessibility. Unlike disposal or destruction, repurposing extends the lifecycle of resources by leveraging existing properties for alternative applications, often driven by practicality, scarcity, or innovation. The term encompasses both physical and non-physical domains: for tangible items, it may involve simple reconfiguration, such as transforming wooden pallets into furniture; for intangible assets like software code or archival , it entails redeployment for unforeseen purposes without altering substance. Repurposing inherently emphasizes functionality over aesthetic enhancement or value escalation, distinguishing it as a pragmatic strategy that avoids the energy-intensive processes of material decomposition. Historical and contemporary examples, from wartime helmet conversions to modern urban of industrial sites, illustrate its role in resource optimization without requiring specialized industrial infrastructure. Repurposing entails redirecting an object, , or to a function divergent from its original intent, frequently with limited modification to enable the new application. This differs from , which involves repeated utilization of an item for its designed purpose without substantive change, such as refilling a or extending garment wear through mending. preserves the item's primary utility and requires no reconfiguration, whereas repurposing demands recontextualization, often fostering but potentially compromising the original form's integrity. In distinction to recycling, repurposing avoids breakdown and reprocessing of materials into raw inputs for novel production; recycling typically entails industrial disassembly, melting, or chemical treatment to yield new goods, which can entail energy-intensive steps and quality loss unless advanced techniques mitigate . For instance, recycling bottles grinds them into pellets for fresh containers, contrasting with repurposing those bottles into via simple cutting. Empirical assessments indicate recycling recovers materials at rates varying by type—e.g., aluminum at over 50% efficiency in the U.S. as of —but repurposing circumvents such processing losses by retaining the item's embodied structure. Upcycling represents a specialized form of repurposing wherein the reassigned use generates a product of equal or elevated economic, functional, or aesthetic value relative to the source, such as transforming scraps into high-end apparel. , conversely, aligns more closely with certain outcomes where materials devolve to lesser-grade applications, like converting mixed plastics into lower-durability park benches, but repurposing broadly encompasses both value-ascending and descending shifts without mandating material reconfiguration. , a domain-specific variant in and , applies repurposing to edifices by reallocating structures—e.g., converting warehouses to residences—while minimizing ; this preserves up to 50-75% of embodied carbon compared to new , per lifecycle analyses conducted through 2025. Unlike mere , which sustains the original function through upgrades, fundamentally alters programmatic intent, often integrating modern amenities into heritage shells.

First-Principles Rationale

Repurposing emerges from the recognition that physical materials possess inherent structural order that can be redirected to alternative functions with minimal additional input, thereby extending utility without the full thermodynamic costs of , refinement, and fabrication of new items. Finite natural resources necessitate strategies that preserve existing and material integrity; repurposing achieves this by adapting durable forms—such as metals, plastics, or composites—directly into secondary roles, avoiding the entropy-increasing processes of disassembly and reprocessing that characterize disposal or full . This approach aligns with causal chains where initial investments in low-entropy configurations yield prolonged value, reducing the net demand on primary inputs like ores or derivatives, which require high expenditures to concentrate and shape. Economically, repurposing rationalizes by circumventing the and operational expenses of virgin , where costs encompass not only direct energy but also environmental externalities like abatement and habitat restoration. For instance, reusing components in can yield energy savings of 4 to 46 percent relative to equivalent new builds with comparable performance, as the avoided phase eliminates upstream expenditures on sourcing and processing. This efficiency stems from market signals favoring lower-cost alternatives: entities repurpose when the marginal utility of adaptation exceeds replacement costs, fostering adaptive innovation without subsidies distorting true scarcity signals. Empirical lifecycle assessments confirm that such practices offset by up to 88 percent compared to alone, underscoring the causal linkage between preserved material flows and reduced systemic burdens. In essence, the viability of repurposing rests on empirical hierarchies prioritizing direct reuse over transformative cycles, as validated by waste management frameworks that sequence refuse, reduce, reuse, and repurpose ahead of recycling to maximize resource retention. This sequence reflects observed causal outcomes: intact items retain higher utility value than fragmented recyclates, which suffer quality degradation and yield losses during remelting or reforming. By leveraging human ingenuity to match existing artifacts to unmet needs—such as converting shipping containers into housing—repurposing demonstrates scalable potential for resilience in resource-constrained environments, provided adaptations do not compromise safety or functionality.

Historical Context

Pre-20th Century Practices

In , the practice of —the repurposing of architectural elements such as columns, capitals, and friezes from demolished or ruined structures into new buildings—was widespread, particularly from the AD onward, as evidenced by the incorporation of pagan materials into early Christian basilicas like Old St. Peter's. This approach conserved resources in an era of limited stone quarrying and symbolized cultural continuity or triumph, with examples including the reuse of marble from imperial forums in medieval Roman churches. Pre-industrial societies routinely repurposed metals by melting scrap bronze tools and weapons into new implements during the , a large-scale activity documented through archaeological evidence of recycled alloys in artifacts across and the around 3000–1200 BC. Similarly, in colonial America during the 18th century, blacksmiths like refabricated old iron and brass from household items and military hardware into horseshoes and other utilitarian goods due to import restrictions and material shortages. In 19th-century , decommissioned wooden warships were dismantled and their and timbers repurposed as structural beams, floorboards, and furniture in buildings, leveraging the wood's pre-seasoned durability from exposure to extend usability amid naval fleet modernizations. Textiles were also commonly altered; garments worn multiple times were mended, resized, or converted into underclothing or rags before the advent of mass-produced apparel around 1900. These practices stemmed from economic necessity rather than organized , reflecting adaptive responses to in agrarian and early mercantile economies.

20th Century Scarcity-Driven Repurposing

The , spanning from 1929 to the late , prompted extensive repurposing of everyday materials due to severe economic constraints and material shortages. In the , households commonly transformed printed and feed sacks into , quilts, and linens, as new fabric was unaffordable for many families. Flour mills responded by offering sacks in colorful patterns to facilitate this practice, which extended into rural and urban areas alike, reducing waste while addressing clothing needs. This repurposing was driven by necessity, with women often sewing dresses and undergarments from these sacks, a trend that persisted until the mid-20th century in some regions. World War II intensified scarcity-driven repurposing across Allied nations, particularly through government-led initiatives amid rationing of textiles and metals starting in 1941. In the , the Ministry of Information's "" campaign, launched in 1943, instructed citizens to repair garments, convert men's suits into women's dresses, and remake woolens by unpicking and reknitting to extend usability under clothing coupon systems allocating 66 points per adult annually. Similar efforts encouraged salvaging and reusing household items, though focused more on scrap collection for industrial remelting, with civilians adapting old blankets into coats and tires into utility mats. Postwar Europe, facing reconstruction amid lingering shortages into the late 1940s, saw military surplus repurposed for civilian needs; for instance, captured German helmets were converted into chamber pots and strainers in the following occupation. from bombed cities was systematically reused in building foundations and roads, enabling rapid despite raw material deficits, as industrial plants remained largely intact but labor and supplies were scarce. These practices stemmed from immediate postwar economic crises, prioritizing functional adaptation over new production until supply chains stabilized.

Late 20th to Early 21st Century Evolution

In the late , repurposing shifted from primarily scarcity-driven necessities toward deliberate strategies emphasizing environmental conservation and resource optimization, influenced by growing awareness of waste generation amid rising . The saw expanded municipal recycling programs in response to landfill pressures, with U.S. municipal solid waste generation reaching 152 million tons annually by 1988, prompting initial explorations of beyond breakdown into raw materials. This period coincided with economic recessions, such as in the UK during the late and early 1990s, where custom repurposing of clothing and goods gained traction among youth as a cost-effective alternative to new purchases. A pivotal development occurred in 1994 when German engineer Reiner Pilz introduced the term "" in an interview with Salvo magazine, describing it as upgrading discarded materials into higher-value items rather than them into lower-grade uses, thereby critiquing conventional recycling's inefficiencies. This conceptualization aligned with emerging principles, amplified by global events like the 1992 Conference on Environment and Development in , which emphasized minimization through in its framework. By the 1990s, creative reuse centers began proliferating in urban areas, diverting materials from landfills for artistic and functional applications, reflecting a cultural pivot toward viewing as a resource. Into the early 21st century, proliferated with digital platforms facilitating knowledge sharing, as evidenced by the launch of sites like in 2005, which enabled marketplaces for repurposed goods and boosted small-scale production. Publications such as and Michael Braungart's 2002 book Cradle to Cradle: Remaking the Way We Make Things advocated as integral to closed-loop systems, influencing industrial practices to prioritize material valorization over disposal. Empirical outcomes included sector-specific innovations, like fashion's "trashion" movement coined in 2004, which repurposed textiles into high-end garments, though scalability remained limited by labor-intensive processes and inconsistent supply chains. Despite these advances, repurposing's adoption lagged behind , comprising a minor fraction of —U.S. reuse rates hovered around 10-15% of municipal waste through the —due to entrenched linear production models.

Advantages

Economic Incentives and Outcomes

Repurposing incentivizes economic activity by lowering input costs compared to sourcing new materials or disposing of , as repurposed items bypass , , and expenses. Businesses adopting repurposing strategies, such as converting byproducts into usable components, can achieve substantial reductions in operational costs; for example, strategic repurposing has enabled companies to cut disposal expenses by 30-50% through decreased volume sent to landfills. Additional drivers include from selling upcycled products, which adds value to low-grade , and incentives that reward efforts, often extending to repurposing as part of broader circular practices. Empirical outcomes demonstrate net savings and growth in secondary markets, with repurposing extending product lifecycles and deferring demand for virgin resources, thereby reducing overall expenditures relative to anew. In the United States, and related activities supported 681,000 jobs and generated $37.8 billion in wages alongside $5.5 billion in in , outperforming landfilling in job creation per of material handled. variants of repurposing prove cost-effective in 62.6% of examined cases, fostering in value-added applications while minimizing environmental compliance costs. Sector-specific data underscores these benefits; healthcare facilities repurposing operating room into resources have realized annual savings of $15,000 to $252,000 per by diverting materials from disposal . Similarly, beneficial practices in can slash total costs by up to 60%, with potential offsets via tax credits for donated repurposed goods. These outcomes hinge on efficient and , yet consistently yield positive returns where scale allows avoidance of high disposal fees and raw material volatility.

Resource Conservation Potential

Repurposing and products conserves resources by extending their functional utility without the need for virgin or energy-intensive primary processes. Unlike disposal or even , which often involves and reprocessing with associated losses, repurposing leverages existing structures and components for applications, thereby minimizing the demand for new inputs. assessments (LCAs) indicate that such practices can offset up to 88% of compared to building components, as the avoidance of and remanufacture phases preserves . Similarly, in industrial contexts like tool optimization, repurposing disrupts linear production chains, reducing overall resource throughput and environmental burdens from and . Energy savings represent a core conservation benefit, as producing goods from repurposed items typically requires far less power than fabricating equivalents from scratch. For instance, remanufacturing processes—closely aligned with repurposing for durable goods—can achieve over 80% reductions in energy use relative to new production, particularly for energy-consuming products like machinery or . In construction, repurposing elements such as or timber yields 35-38% lower demand alongside decreased water consumption and , based on comparative LCAs of versus demolition and rebuild scenarios. These efficiencies stem from bypassing extraction phases, where activities like mining or account for substantial upfront energy and habitat disruption, and from curtailing downstream , which otherwise consumes resources for landfilling or . Broad material resource preservation further underscores repurposing's potential, as it diminishes reliance on finite stocks of metals, plastics, and . Reusing furniture through repurposing, for example, can cut carbon footprints by 36% per item like a by avoiding new timber harvesting and composite fabrication. For metals, which embody high extraction costs, repurposing helmets or rails into tools or fencing conserves ores that would otherwise require energy-prohibitive beneficiation. Empirical data from EPA analyses affirm that reduction and hierarchies, including repurposing, outperform in safeguarding by prioritizing in-use circulation over material recovery loops prone to quality degradation. However, realization of this potential hinges on ; while LCAs demonstrate systemic gains, localized inefficiencies in collection or can erode benefits if not managed through targeted design for adaptability.

Innovation and Adaptability Examples

Repurposing demonstrates adaptability by transforming existing materials or structures for unforeseen applications, often spurring creative solutions amid resource constraints or evolving needs. In , the of industrial buildings has pioneered multifunctional spaces that preserve historical elements while enabling modern functions. For instance, London's , constructed between 1947 and 1963 and decommissioned in 1981, was converted into the gallery by , opening on May 11, 2000. This project innovated by retaining the vast turbine hall as an open exhibition space for large-scale , challenging traditional layouts and revitalizing a derelict riverside site into a global cultural hub. Shipping containers, originally standardized for global freight transport in the 1950s, exemplify industrial repurposing for housing innovation. By the 1980s, architects began adapting these steel units into modular homes, leveraging their durability, stackability, and abundance to cut construction costs and timelines. Projects like the Caterpillar House in , completed in 2014, integrated containers into sustainable designs with features, demonstrating how repurposing enables rapid, eco-efficient building in remote or disaster-prone areas. Such adaptations have scaled to commercial ventures, with firms producing prefabricated units that assemble in weeks rather than months, fostering affordability in urban expansion. During , material scarcity drove grassroots repurposing innovations, particularly with military parachutes made of , , and . In occupied , civilians transformed surplus or recovered parachutes into , such as dresses, underwear, and sails for boats, adapting lightweight fabrics to civilian survival needs. This opportunistic not only addressed immediate shortages but also influenced post-war textile applications, highlighting repurposing's role in rapid technological and cultural adaptation under duress.

Criticisms and Empirical Limitations

Operational Inefficiencies

Repurposing used materials or products for new applications introduces operational inefficiencies primarily due to the non-standardized nature of inputs, which demands extensive preprocessing compared to virgin resources. Acquisition of repurposable items often faces in timing, volume, and condition, complicating and increasing costs. In contexts, this variability requires labor-intensive disassembly, cleaning, and , elevating initial expenses and extending lead times. Quality inconsistencies further exacerbate inefficiencies, as repurposed materials frequently exhibit defects or compositional variations that undermine product performance. A review of 127 studies on circular found that 49.6% reported diminished in repurposed products, necessitating additional R&D for modular adaptations and risking higher rejection rates in . In , empirical analysis of major firms like and Kiewit from 2015–2019 revealed that while boosts efficiency, it demands substantial upfront investments—1.3–2.3% more capital per 1% efficiency gain—often with long payback periods that delay profitability. Scalability remains limited by these factors, as complex for sourcing and processing heterogeneous materials hinder , contrasting with the uniformity of new material supply chains. Lack of advanced and tracking systems compounds this, leading to incomplete material inventories and suboptimal decisions, particularly in sectors like and demolition . Economic barriers, including insufficient financial incentives for such overheads, often render large-scale repurposing less competitive than disposal or alternatives.

Overstated Environmental Impacts

Proponents of repurposing frequently assert substantial reductions in and , often citing avoided virgin material extraction as primary benefits. However, lifecycle assessments reveal that these impacts are conditional and frequently overstated, as they neglect use-phase inefficiencies and ancillary costs such as , , and . For instance, while can save up to 80% of energy compared to new production in cases like electric motors, the net environmental gain diminishes when repurposed items retain outdated efficiencies that elevate operational emissions over time. Empirical studies highlight scenarios where repurposing yields neutral or adverse outcomes relative to replacing with new, efficient alternatives. Reused powered products, such as refrigerators, can consume 60% more due to accumulated and obsolete designs, thereby increasing total lifecycle emissions despite deferred impacts. Similarly, repurposing smartphones without sufficient refurbishment has been shown to heighten environmental burdens through energy-intensive processes that fail to match the of newly produced devices. In building materials, oversizing repurposed beams to compensate for requires additional , amplifying and emissions by factors tied to design mismatches. These findings underscore that unupgraded repurposing locks in suboptimal performance, often undercutting claimed savings when benchmarked against rapid technological advancements in new goods. Rebound effects further erode purported benefits, as cost reductions from repurposing incentivize higher volumes, partially or fully offsetting resource conservation. Household-level analyses of circular practices indicate rates that can diminish footprint reductions by stimulating additional demand, with from patterns showing incomplete of virgin products—e.g., only 60-85% of reused garments preventing new purchases. Broader critiques of strategies, including repurposing, note that such dynamics perpetuate systemic inefficiencies without addressing entropy-driven degradation or incentivizing innovation in efficiency, leading to exaggerated narratives of decoupled from verifiable net gains. Academic sources, while generally rigorous, sometimes amplify optimistic projections by prioritizing production-phase metrics over holistic assessments, a tendency observed in policy-influenced .

Market and Policy Distortions

subsidies for virgin , including incentives for and , artificially lower the costs of new goods, thereby reducing economic incentives for consumers and producers to pursue repurposing options that might otherwise compete on price. These distortions persist because such subsidies, often justified on job-creation grounds, ignore the full lifecycle costs and externalize environmental impacts, favoring linear models over market-driven . Extended Producer Responsibility (EPR) policies, adopted in regions like the and several U.S. states as of 2024, impose financial obligations on manufacturers for product disposal and , intending to internalize waste costs but frequently resulting in elevated administrative fees and compliance burdens that disproportionately affect smaller repurposing operations. Economic analyses indicate that EPR's non-neutral treatment of manufacturing processes—penalizing certain materials without equivalent incentives for repurposed alternatives—can undermine efficiency by distorting supply chains and diverting resources from viable pathways to mandated collection systems with low rates. Regulatory frameworks exacerbate these issues by applying inconsistent standards, such as heightened and requirements for repurposed products that exceed those for virgin equivalents, thereby increasing entry barriers and operational costs for innovators in reuse markets. For instance, product guarantee laws and insurance stipulations often treat repurposed items as higher-risk, deterring investment despite of comparable in many applications, as seen in case studies of reuse where compliance delays added 20-30% to project timelines. These barriers reflect a precautionary approach that prioritizes perceived risks over probabilistic assessments, stifling adaptive repurposing without verifiable gains. Trade interventions, including China's 2018 ban on foreign waste imports, exposed latent distortions in subsidized Western programs, where policies had encouraged over-collection of low-value materials like mixed plastics without domestic repurposing capacity, leading to stockpiling and diversion rather than genuine circularity. In the U.S., municipal subsidies for infrastructure, totaling billions annually, have sustained operations despite negative net values for certain commodities—evidenced by 2023 market data showing processed recyclables often resold below collection costs—thus masking inefficient and crowding out private repurposing initiatives driven by profit signals.

Applications in Practice

Consumer Goods and Household Materials

Repurposing consumer goods and household materials involves redirecting used items from disposal to new domestic applications, such as transforming into solutions or furniture components into alternative fixtures, which extends utility and mitigates accumulation. In practice, households commonly adapt jars from containers into organizers, dispensers, or decorative holders, while bottles are modified into or funnels, preserving material value without industrial processing. Textiles and apparel, including worn and , are frequently converted into cleaning rags, , or craft materials, circumventing the energy-intensive of disposables. Bulky items like furniture represent a substantial category, with UK households discarding around 670,000 tonnes annually, of which over 20% is reusable in its current state and up to 50% viable after minor repairs at household waste centers. In the United States, approximately 9 million tons of furniture reach landfills yearly, underscoring untapped repurposing potential for items like doors repurposed as tables or ladders as racks. Such adaptations yield environmental gains, with furniture linked to roughly 42% lower impacts relative to equivalents, primarily through avoided and emissions. However, empirical assessments reveal effects, where monetary savings from reuse prompt increased spending elsewhere, potentially offsetting 82-167% of anticipated reductions for furniture via induced consumption. Net outcomes hinge on behavioral factors, including sustained product and substitution of new purchases, rather than supplemental acquisition.

Manufacturing and Industrial Adaptation

Manufacturing repurposing refers to the rapid reconfiguration of capacities, processes, and to manufacture products distinct from a firm's original output, often driven by external shocks such as supply disruptions or demand surges. This leverages existing to minimize startup costs and timelines, though it requires overcoming barriers like regulatory hurdles and gaps. Empirical studies identify macro factors including incentives and approvals, alongside micro elements such as agile know-how. A prominent historical instance occurred during , when U.S. manufacturers shifted from consumer goods to military hardware. Automobile production, which totaled approximately 3 million vehicles in , largely halted as factories converted to , , and ships; for example, facilities previously assembling cars produced over 86,000 and contributed to 297,000 across the war effort. This transition, facilitated by federal contracts and resource reallocation, scaled output dramatically, with aviation expanding from peacetime levels to sustain Allied operations. In response to the , numerous firms repurposed lines for medical supplies. In the UK, small manufacturers like Display Mode scaled to 70,000 visors per week by March 2020, ultimately producing 7-8 million units, while Midton Acrylics delivered 10,000 disposable visors in 3.5 weeks using acrylic expertise. Globally, converted facilities to hand sanitizers, and Ferrari adapted machinery for respirator valves, with 45 analyzed cases showing production of face shields, masks, and ventilators peaking in March-June 2020 amid shortages. These efforts, often initiated within weeks via collaborations and relaxed standards, addressed immediate gaps but highlighted dependencies on material availability. Ongoing adaptations emphasize circular manufacturing, where equipment and materials are reused to extend lifecycles and cut emissions. Strategies include modular designs facilitating disassembly for component repurposing, as in batteries redirected to stationary storage systems, and real-time monitoring to optimize reuse decisions. equipment repair and redeployment, rather than scrapping, conserves resources; for instance, recommissioning idle machines reduced waste in apron production during crises. Tires and electronics components are routinely repurposed into aggregates or new devices, supported by inter-firm partnerships, though scalability remains constrained by needs.

Pharmaceutical Repurposing

Pharmaceutical repurposing, also known as , entails identifying and validating new therapeutic indications for existing drugs that have already undergone safety and pharmacokinetic testing. This approach leverages accumulated clinical data to bypass early-stage development hurdles, potentially accelerating approval for novel uses. Unlike drug discovery, which typically spans 10-15 years and incurs costs exceeding $2 billion per successful candidate due to high rates—where approximately 90% of candidates fail in clinical trials—repurposing can shorten timelines by 5-7 years and reduce expenses by utilizing established formulations and dosing knowledge. Empirical advantages include higher clinical success rates, estimated at 30% for repurposed candidates compared to 10% for novel compounds, attributed to pre-existing human data that mitigates toxicity risks. For instance, repurposed drugs account for about 25-40% of annual pharmaceutical revenues, reflecting market viability when new patents or orphan drug designations extend exclusivity. Strategies encompass serendipitous observations from side effects, computational screening of molecular targets, and phenotypic assays, with preclinical validation often confirming efficacy in disease models before phase II trials. However, success hinges on robust evidence; anecdotal repurposing claims require rigorous validation, as off-target effects or disease-specific pharmacokinetics can undermine outcomes. Notable cases illustrate practical impacts. , initially developed in the 1980s for and by , was repurposed in 1998 for after trial participants reported improved erections, leading to Viagra's approval and generating over $1 billion in annual sales by 2008. Aspirin, synthesized in 1897 for pain relief, gained cardiovascular indications in the 1980s following trials like the Physicians' Health Study (1989), which demonstrated reduced risk by 44% in men taking low-dose aspirin. , withdrawn in 1961 for teratogenicity after causing birth defects when used for , was repurposed in 1998 for after showing anti-angiogenic effects, with FDA approval under strict controls yielding remission rates up to 70% in combination therapies. , approved in 1979 for , was repositioned in 1988 for androgenetic alopecia based on observed side effects. These examples highlight causal mechanisms—such as inhibition for sildenafil or platelet aggregation blockade for aspirin—driving efficacy across indications. Challenges persist, including diminished economic incentives for patent-expired generics, where developers recoup investments less readily without exclusivity extensions, leading to shelved candidates despite . Regulatory frameworks demand new indication-specific trials, often costing hundreds of millions, while consolidation prioritizes high-margin novel drugs over repurposing's lower returns. In rare diseases or , where development falters due to small markets, repurposing shines—evidenced by initiatives like the FDA's 1983 Orphan Drug Act facilitating thalidomide's revival—but systemic barriers, such as insufficient funding for validation studies, limit scalability. Empirical reviews indicate that while repurposing mitigates root causes like poor in original trials, only a fraction of candidates advance, underscoring the need for targeted incentives to realize causal potentials.

Real Estate and Urban Infrastructure

Adaptive reuse in involves converting existing structures, such as obsolete office buildings or industrial warehouses, into residential, commercial, or mixed-use spaces, thereby avoiding and leveraging pre-existing foundations and materials. This practice has gained traction in urban areas facing vacancy rates, with policies like Los Angeles's 1999 Adaptive Reuse Ordinance facilitating conversions by streamlining permitting for historic buildings, resulting in over 7,000 new residential units by 2021. Empirical analyses indicate that such repurposing typically yields environmental advantages over new construction; for instance, a life-cycle assessment of historical building adaptations in showed an 82% reduction in , a 51% decrease in formation, and a 27% drop in acidification compared to and rebuild scenarios. In urban infrastructure, repurposing extends to linear assets like abandoned rail corridors transformed into pedestrian trails, enhancing connectivity while minimizing land acquisition costs. The in exemplifies this, where a 1.45-mile elevated freight rail line, disused since 1980, was converted into a opened in phases from 2009 to 2019, attracting over 8 million visitors annually and spurring $2 billion in adjacent development. Similarly, Atlanta's project repurposes 22 miles of former rail tracks into a multi-use trail network, incorporating housing and transit elements, with completion targeted for 2030 and already generating $10 billion in economic impact since inception in 2005. These initiatives, supported by organizations like the Rails-to-Trails Conservancy, have converted over 25,000 miles of rail infrastructure nationwide into trails by 2023, promoting active transportation and reducing pressures. Cost comparisons further underscore repurposing's viability; a study of U.S. building projects found averts expenses—often 10-20% of total new-build costs—and preserves equivalent to 30-50% of a structure's lifetime operational . However, challenges include restrictions and structural retrofits, as seen in conversions of pandemic-era vacant hotels into housing, where developers like The Estate Companies navigated regulatory hurdles to repurpose distressed properties in starting in 2020. In , projects like the transformation of derelict malls into mixed-use hubs demonstrate scalability, with one case study reporting 53-75% lower environmental impacts across categories like when renovating versus rebuilding.

Recent Developments

Crisis Response and Adaptive Strategies

In response to the , manufacturing sectors worldwide adapted by repurposing production lines to address acute shortages of medical supplies. Over 2,700 facilities owned by large firms were identified as capable of rapid retooling to produce items such as ventilators and , enabling scaled output within weeks of demand surges in early 2020. Similar shifts occurred globally, with automotive converting assembly lines for sanitizer and masks, which mitigated disruptions caused by border closures and scarcity. The Russia-Ukraine war since 2022 has driven material repurposing strategies to manage vast quantities of construction debris from bombardments, estimated at millions of tons. Initiatives supported by the involve dismantling rubble from destroyed buildings, separating hazardous materials like , and processing remnants into aggregates for road base and new , thereby reducing burdens and costs. UK researchers from the have advanced techniques for salvaging and reusing bombed and , testing methods to restore structural integrity for post-conflict rebuilding as of 2025. These efforts counter resource shortages exacerbated by disrupted imports, with experimental processes grinding debris into reusable components akin to reversing raw material . In during the 2020s, such as wildfires and floods intensified by climate variability, communities have employed repurposing for immediate and recovery. For example, after in 2021, salvaged timber and metal from debris was adapted into temporary housing frames in affected U.S. Gulf regions, leveraging local labor to bypass delayed federal aid. Broader adaptive frameworks emphasize pre-positioning reusable modular units from prior events, as seen in Australia's 2019-2020 bushfires where shipping containers were repurposed into emergency clinics, demonstrating causal efficiency in minimizing downtime through existing stock rather than new procurement. These strategies highlight repurposing's role in enhancing by prioritizing empirical resource audits over speculative planning.

Technological and Policy Advances

Advances in (AI) and have enhanced material sorting for repurposing, enabling automated identification and separation of waste streams with over 95% accuracy in some systems, reducing contamination in recycling processes that facilitate subsequent repurposing into higher-value products. technology has been integrated into supply chains to track repurposed materials, ensuring provenance and quality, as demonstrated in pilots where it supports verifiable loops for plastics and . Chemical recycling innovations, such as catalytic hydrogenolysis, convert non-recyclable plastics into monomers for new polymers, achieving up to 90% in lab-scale processes and enabling repurposing of single-use into durable goods like casings. applications break down composites at molecular levels, allowing repurposing of mixed materials like reinforced plastics into enhanced composites, with pilot projects reporting 20-30% improved material strength post-processing. Polymer engineering advancements, including enzymatic , target specific types for , as in bio-based catalysts that degrade polyethylene terephthalate () into reusable , scaling commercially since 2023. On the policy front, the European Union's 2024 Directive on empowering consumers for the green transition mandates clearer labeling for repairability and , indirectly boosting repurposing by extending product lifecycles through informed decisions. In the United States, the Department of Energy's 2024 Circularity for Secure and initiative funds R&D for material redesign, allocating $50 million toward technologies that prioritize repurposing critical minerals from over virgin extraction. National plans, such as Brazil's 2025 Strategy public consultation, emphasize incentives for industrial repurposing, targeting a 20% reduction in landfill via tax credits for upcycled outputs, though implementation efficacy remains data-limited as of mid-2025. These policies often face criticism for over-reliance on subsidies without addressing market distortions from subsidized virgin materials, per analyses of roadmaps.

Future Trajectories and Uncertainties

Repurposing practices are projected to integrate more deeply into models, with the estimating that transformative strategies could unlock economic value by extending product lifecycles and minimizing raw material extraction through and . Key drivers include technological innovations like AI-enabled material identification and digital tracking systems, which are expected to improve recovery rates for diverse waste streams by 2025. Policy advancements, such as frameworks in regions like the , aim to incentivize repurposing over landfilling, potentially reducing generation impacts as global volumes are forecasted to reach 3.8 billion tonnes annually by 2050. Despite these trajectories, empirical assessments reveal persistent gaps, as recycled and repurposed material volumes have risen but failed to offset accelerating demand for primary resources, per the 2025 Circularity Gap Report, underscoring the need for systemic reductions in overall consumption. In sectors like , repurposing's expansion hinges on scalable processes, with emerging trends in technologies projected to enhance viability in high-volume applications such as . Uncertainties loom large in achieving widespread adoption, primarily due to supply chain inconsistencies—such as variable quality and availability of feedstocks—which hinder predictability for industrial-scale operations. Economic analyses highlight cost barriers, where repurposed materials often exceed virgin alternatives in processing expenses without subsidies, compounded by infrastructural deficits in sorting and decontamination. Regulatory flux introduces further variability, as enforcement of waste directives varies globally, potentially stalling progress if incentives falter amid competing priorities like energy security; peer-reviewed reviews emphasize that causal links between policy intent and scaled outcomes remain empirically unproven at volume. Consumer and market acceptance adds volatility, with upcycling's niche appeal limiting demand unless quality parity is achieved, as evidenced by stalled growth in craft-dependent models.

References

  1. [1]
    Repurposing: How it Works, Role in Digital Content, Examples
    Repurposing, when performed as a way to reduce waste and supplant a new, manufactured good is an element of micro-sustainability, which is a focus on small ...
  2. [2]
    Recycling vs Repurposing vs Reusing - UBQ Materials
    Sep 11, 2025 · What Is Repurposing? ... Repurposing involves taking an item and giving it a new function, different from what it was originally intended for.Missing: definition | Show results with:definition
  3. [3]
    So What's the Difference? Reuse, Recycle, Repurpose
    Jan 29, 2020 · Reuse is any activity that lengthens the life of an item. Recycling is the reprocessing of an item into a new raw material.
  4. [4]
    Reusing, Recycling, and Upcycling: A Primer - Boise State University
    Oct 27, 2023 · Reusing: This involves taking items that might otherwise be considered waste and finding new applications for them, without changing the ...
  5. [5]
  6. [6]
    The History of Adaptive Reuse: Breathing New Life Into Old Structures
    Jun 4, 2024 · The concept of adaptive reuse has ancient roots. Historically, structures were often repurposed due to the scarcity of building materials and ...<|separator|>
  7. [7]
    Repurposing Fashion: A 19th Century Woman's Guide to Thrift
    Oftentimes, examples of eighteenth century reused fabric or altered gowns are found in clothes dating from 1835 through 1845.
  8. [8]
  9. [9]
    Understanding the key differences and advantages - Reuse Minnesota
    Jul 18, 2024 · From an environmental perspective, the impact of reuse versus recycling is quite different. Reuse reduces the need for new raw materials, ...
  10. [10]
  11. [11]
    Recycling vs. Upcycling vs. Reuse
    Jun 4, 2024 · Unlike traditional recycling that breaks down materials into raw components and builds them back up, upcycling involves transforming discarded ...
  12. [12]
    What is adaptive reuse? Repurposing buildings for a sustainable ...
    Adaptive reuse repurposes existing buildings for new uses, cutting waste and carbon while preserving history. It's a sustainable alternative to demolition.
  13. [13]
    From Waste to Wealth: Repurposing Materials for Sustainable ...
    Feb 17, 2025 · Some common examples of repurposed materials used in construction include reclaimed wood, recycled glass, recycled steel, and crushed concrete.<|control11|><|separator|>
  14. [14]
    Industrial Equipment Reuse - Armatec Environmental Ltd
    May 14, 2024 · Examples of Reuse of Equipment and Manufacturing Waste: Reuse of industrial equipment can include a range of opportunities from formal to ...
  15. [15]
    Examples of Creative Re-Use of Surplus Materials - Core77
    Oct 10, 2023 · The company buys up surplus inventory and difficult-to-recycle items, then re-sells them; all of it can be given a second life with a little creativity.
  16. [16]
    Understanding Repurpose, Recycle, Upcycle, and Reclaimed
    Jul 8, 2024 · Definition: Repurposing is about finding a new use for an existing item without fundamentally changing its structure. This method breathes new ...
  17. [17]
  18. [18]
  19. [19]
    Repurpose - UNEP circularity platform
    In repurpose, by reusing discarded goods or components adapted for another function, the material gets a distinct new life cycle.
  20. [20]
    Repurpose - Definition, Meaning & Synonyms - Vocabulary.com
    When you repurpose something, you use it again in an entirely new way. You might decide to repurpose rinsed-out yogurt containers to grow flower seedlings on ...<|separator|>
  21. [21]
    Reuse, Recycle, Repurpose: What's the Difference? - USAgain
    Apr 14, 2025 · Let's explore the key differences between textile reuse, recycling, and repurposing and why reuse should always come first. Textile Reuse ...
  22. [22]
  23. [23]
    Reducing and Reusing Basics | US EPA
    Sep 13, 2025 · Reduction and reuse are the most effective ways you can save natural resources, protect the environment and save money.
  24. [24]
    What's the Difference Between Upcycling and Downcycling?
    While upcycling allows for reclamation or reuse of the same materials for new products, downcycling deals with degraded materials that don't possess enough ...
  25. [25]
    Adaptive reuse can help reimagine, repurpose and revitalize cities
    Apr 30, 2025 · Repurposing an existing building emits 50-75% less carbon than constructing the same building new. When adaptive reuse is paired with ...
  26. [26]
    [PDF] Quantifying the environmental Value of building reuse - Living Future
    Savings from reuse are between 4 and 46 percent over new construction when comparing buildings with the same energy performance level.
  27. [27]
    Exploring environmental benefits of reuse and recycle practices
    Our results indicate that, compared to recycling, designing and building for reuse components offsets greenhouse gas emissions by 88%.
  28. [28]
    Recycling Basics and Benefits | US EPA
    Sep 2, 2025 · Recycling can benefit your community, the economy, and the environment. Products should only be recycled if they cannot be reduced or reused.
  29. [29]
    The 5 R's: Refuse, Reduce, Reuse, Repurpose, Recycle
    According to the 5 R's, four actions should be taken, if possible, prior to 'recycling': refuse, reduce, reuse, repurpose, and then recycle.Missing: rationale | Show results with:rationale
  30. [30]
    Spolia | recycled elements of ancient buildings - Peter Sommer Travels
    Aug 26, 2013 · It describes is simply the reuse of elements from earlier buildings in more recent ones, most typically the reuse of Greek or Roman architectural sculpture.
  31. [31]
    Architectural Spolia and Urban Transformation in Ancient and ...
    Jun 27, 2024 · This paper is a historical outline of the practice of reuse in Rome between the 4th and 5th century AD. It comments on the relevance of the Arch ...
  32. [32]
    Ancient Populations Pioneered the Idea of Recycling Waste | MPIWG
    Jan 9, 2019 · Ancient practices like reusing old tools, recycling pottery, and the large-scale recycling of bronze in the Bronze Age, show early circular ...Missing: industrial | Show results with:industrial
  33. [33]
    Paul Revere Recycled: How More Than Two Centuries of Material ...
    May 2, 2017 · Paul Revere recycled, though he did not use that word. British restrictions on colonial metal production compelled blacksmiths to melt down and refabricate old ...Missing: repurposing | Show results with:repurposing
  34. [34]
    How Victorian engineers recycled old warships into building materials
    Oak and elm, once part of gun decks and hulls, were recut into beams, floorboards and even furniture. Ship's timbers, pre-seasoned by years of exposure to ...
  35. [35]
    Clothes Tell Stories: Reuse and Recycle
    Before the development of readymade clothing in the 20th century, people would use and reuse their clothing throughout the majority of their lives. Textiles ...Missing: repurposing | Show results with:repurposing
  36. [36]
    Make Do: Feed-Sack Fashion in the First Half of the Twentieth Century
    Nov 11, 2020 · Feed-sack fashion involved reusing cloth bags for flour and feed to make clothing, especially during the Great Depression and WWII, to save ...
  37. [37]
    From Flour Sack to Fashion Hack: A Brief History of Great ...
    During the Great Depression, flour sack dresses were made from cheap flour sacks. Women also used old clothing and buttons, and were taught sewing by WPA.
  38. [38]
    The Unusual Material People Made Clothing With During The Great ...
    Nov 19, 2020 · The trend of recycling cloth sacks continued all the way until the middle of the 20th century. After the war, fewer families lived in rural ...
  39. [39]
    Make Do And Mend Newsreel - World War 2 1943
    Make Do And Mend: A Ministry of Information film 1943, part of a government campaign in WW2, urged people to repair and reimagine existing clothes.Missing: examples | Show results with:examples
  40. [40]
    8 Facts About Clothes Rationing During World War 2
    Clothes rationing started June 1, 1941, using a 'points' system with coupons. Each adult had 66 points initially, and the 'Make Do and Mend' campaign ...Missing: examples | Show results with:examples
  41. [41]
    Liz Swafford: Recycling and reuse during World War II | Dalton Daily ...
    Jun 17, 2014 · Campaigns like “Save Scrap for Victory” encouraged the collection of metal, paper, rubber and rags for recycling to create military goods.
  42. [42]
    Wartime circularity: adapting buildings, salvaging materials, and ...
    Oct 12, 2025 · Focusing on postwar reconstruction, scholars have shown how state-led rebuilding was enabled by intensive reuse and recycling of rubble ( ...
  43. [43]
    Recovery and reconstruction: Europe after WWII - CEPR
    Nov 21, 2019 · Despite the scale of material damage, industrial equipment and plants survived the war remarkably intact. Even in Germany and Italy, the two ...Missing: repurposing | Show results with:repurposing
  44. [44]
    Recycling through the ages: 1980s - Plastic Expert
    Aug 4, 2014 · In the 1980s, landfill usage peaked, with 86% landfill rates in 1986. Cheap landfill space made recycling less appealing, and the throwaway ...
  45. [45]
    The History Of Upcycling - Alterist
    Technically, the history of upcycling can be traced back to early humans, where reusing and “upcycling” materials and products were simply a part of everyday ...Upcycling In The 19th... · Upcycling In The 1900s · Upcycling In The 1990's
  46. [46]
    Upcycling, the Ongoing Battle - Verfassungsblog
    Apr 17, 2025 · The term “upcycling” was first used in 1994 by Reiner Pilz, a mechanical engineer, in the architecture magazine Salvo.
  47. [47]
    Upcycling: is this eco trend here to stay? - The Independent
    Jul 30, 2010 · In 1994, in an interview with Thornton Kay of Salvo, Reiner Pilz of German technology company, Pilz GmbH said of recycling, "I call it ...
  48. [48]
    Upcycling | Research Starters - EBSCO
    Upcycling is transforming old or discarded items into new, functional objects, unlike traditional recycling, and is a mixture of 'up' and 'recycle'.
  49. [49]
    How Can Businesses Reduce Waste Disposal Costs?
    Jul 17, 2025 · Companies that introduce strategic waste reduction programs typically cut disposal costs by 30-50%. This results in significant savings, with ...
  50. [50]
    10 Financial Incentives for Recycling Manufacturing Waste
    1. Reduced Costs of Manufacturing · 2. Substantial Tax Breaks From the Government · 3. Increased Revenue Streams From Recycled Materials · 4. Reduced Waste ...
  51. [51]
  52. [52]
    Jobs & Economic Benefits of Zero Waste - Eco-Cycle
    Zero Waste programs that reuse, repair, recycle, and compost materials create more jobs than landfills and incinerators per ton of materials handled.
  53. [53]
    Product reuse and repurpose in circular manufacturing: a critical ...
    Mar 6, 2025 · Recent studies have demonstrated that remanufacturing significantly reduces the environmental footprint of manufacturing operations by ...Missing: causal objects evidence
  54. [54]
    The “6th R” of sustainability: Repurposing operating room waste for ...
    Cost savings from these efforts range from $15,000 to $252,000 per institution per year. Recycling remains an important and widely accepted practice in the ...
  55. [55]
    Last Chance to Adopt Beneficial Reuse Waste Management
    Oct 27, 2023 · Cost Savings: Companies can save up to 60% on waste management costs by adopting beneficial reuse practices. Tax Incentives: Donating ...
  56. [56]
    Waste Management Cost Savings | RoadRunner
    Sep 17, 2025 · Reducing landfill output lowers waste management costs and can open up opportunities to repurpose what would otherwise be manufacturing waste.
  57. [57]
    Repurpose – How to upgrade tools and save resources
    Repurpose is a useful way to optimize tools and save resources at the same time. Rethinking production chains of steel products offers huge environmental ...
  58. [58]
    Remanufacturing of energy-consuming products: a smart idea? - Sirris
    May 8, 2025 · In some instances, savings can surpass 80 percent¹ when compared to the production of new products. This often results in a similar reduction in ...
  59. [59]
    What are the energy and greenhouse gas benefits of repurposing ...
    An analysis by Sanchez et al. (2019) found a 35%–38% decrease in primary energy demand, GWP, and water consumption, and 70% savings in construction costs for ...
  60. [60]
    Navigating the Circular Economy: How Reusing Materials Saves ...
    Nov 3, 2021 · Clients can see an average savings of 30 to 50% by purchasing recycled office furniture. Simple reuse of an office desk can reduce carbon footprint by 36%.
  61. [61]
    Remanufacturing and Energy Savings - ACS Publications
    Remanufactured products that can substitute for new products are generally claimed to save energy. These claims are made from studies that look mainly at ...
  62. [62]
    AD Classics: The Tate Modern / Herzog & de Meuron | ArchDaily
    Sep 17, 2013 · The original building was designed by Giles Gilbert Scott in the late 1940s and was decommissioned after just three decades of use. Situated ...
  63. [63]
    Herzog & de Meuron's Tate Modern – the most significant building of ...
    Jan 6, 2025 · Opened in May 2000, the gallery was ahead of its time with its focus on reuse, rejuvenating London's cultural offering and propelling Swiss ...Missing: history | Show results with:history
  64. [64]
    10 Innovative Shipping Container Homes - Rethinking The Future
    10 Innovative Shipping Container Homes · 1. Manifesto House | Shipping Container Homes · 2. Caterpillar House · 3. The Grillagh Water House · 4. The Container Cabin.
  65. [65]
    Surprising Ways People Reused US Military Parachutes During WWII
    Apr 12, 2020 · People made use of the life-saving silk, canvas, and nylon canopy contraptions falling from the sky during World War II everywhere from France and Yugoslavia ...
  66. [66]
    Recycling and Upcycling in the Practice of Waste Management of ...
    The purpose of this study was to assess the impact of recycling and upcycling technologies on the level of efficiency of large construction companies.
  67. [67]
    A critical review on recycling and reuse of construction and ...
    Technically, the lack of advanced sorting systems, inconsistent material quality, and inadequate tracking mechanisms limit effective reuse and recycling (Véliz ...
  68. [68]
    [PDF] The Environmental Impacts of Reuse - MIT
    In this article, we structure the current work on the topic, reviewing the potential benefits and pitfalls described in the literature and providing a framework ...Missing: causal objects
  69. [69]
    Rebound effects may jeopardize the resource savings of circular ...
    Oct 19, 2020 · Rebound effects may jeopardize the resource savings of circular consumption: evidence from household material footprints. Juudit Ottelin, Hale ...
  70. [70]
    Reuse of consumer products: Climate account and rebound effects ...
    This study evaluates the environmental benefits of reuse as a circular economy activity, using a municipal reuse program as case study.Missing: causal objects
  71. [71]
    The case of the underperforming circular economy - Trellis Group
    Oct 18, 2021 · Markets and public policies encourage the use of virgin materials. Subsidies and other market distortions have historically led to the ...Missing: repurposing | Show results with:repurposing
  72. [72]
    Subsidies and government support - OECD
    Unless well-designed, industrial subsidies can distort global markets and waste public resources. As more governments introduce measures to support domestic ...
  73. [73]
    Extended Producer Responsibility (EPR) Policies - Tax Foundation
    Sep 26, 2024 · Non-neutral treatment of manufacturing or recycling processes also threatens to undermine environmental goals and distort markets, a common ...A Blueprint For Sound Policy · A Circular Economy · Important Epr Design...Missing: repurposing | Show results with:repurposing
  74. [74]
    Regulatory barriers for the Circular Economy: Lessons from ten case ...
    Nov 10, 2016 · This report analyses a set of circular economy business practices to identify and suggest policy and regulatory actions to unlock their full growth potential.
  75. [75]
    Challenges and opportunities for reuse of products and materials ...
    Lack of storage. •. Regulations which hinder reuse. •. Product guarantees and insurance. •. Certification requirements lacking certification standards for reuse.Missing: repurposing | Show results with:repurposing
  76. [76]
    Recycling Market Instability → Area
    Recycling market instability refers to the unpredictable fluctuations in the supply, demand, and pricing of recyclable materials.
  77. [77]
    [PDF] MARKET FORCES CAN HELP LOWER WASTE VOLUMES
    RECYCLING MARKET. Policy makers increasingly view recycling as an important element of waste management. It can reduce the amount of waste that ends up in ...
  78. [78]
    The Benefits of Repurposing and Upcycling
    Feb 1, 2023 · 9 million tons of furniture are tossed into landfills each year. One of the best ways to minimize this statistic is through upcycling and refurbishing!<|separator|>
  79. [79]
    [PDF] Second-hand furniture and climate impact - DiVA portal
    The results indicated that reusing furniture resulted in about 42% reduced climate impacts, although it depended on the characteristics of second-hand trade.
  80. [80]
  81. [81]
    Understanding manufacturing repurposing: a multiple-case study of ...
    Jul 28, 2022 · Manufacturing repurposing serves as a balancing mechanism for the overall system. It reduces market demand by producing the required PPE and CCE ...Missing: outcomes | Show results with:outcomes
  82. [82]
    During WWII Industries Transitioned From Peacetime to Wartime ...
    Apr 3, 2020 · To illustrate the magnitude of the transition to wartime production, there were about 3 million automobiles manufactured in the U.S. in 1941.
  83. [83]
    In WW2, American industry provided almost two-thirds of the Allies ...
    Sep 19, 2025 · This includes 297,000 aircraft, 193,000 artillery pieces, 86,000 tanks, and two million army trucks. The WW2 would not have been won without ...
  84. [84]
    The power of repurposing: Case studies | Institute for Manufacturing
    Dec 16, 2020 · Read more about the experience of small firms repurposing in response to COVID-19 in the UK in our individual case studies.
  85. [85]
    The Benefits of Reuse and Recycling Manufacturing Equipment for ...
    Reusing equipment reduces CO2 emissions, provides cost savings, conserves resources, and aligns with a circular economy, contributing to sustainability.<|control11|><|separator|>
  86. [86]
    How drug repurposing can advance drug discovery: challenges and ...
    Drug repurposing plays a key role in reducing the financial burden and accelerating the market entry time of new drugs (Ashburn and Thor, 2004; Pushpakom et al.
  87. [87]
    Advantages of Drug Repurposing - pharm-int
    Reduced development timelines with an average savings of 5-7 years2; · Higher approval rates; · Sales potential: 25% to 40% of annual pharmaceutical revenues can ...
  88. [88]
    Drug Repurposing for Pandemic Innovation: Establishing an ...
    Jun 15, 2023 · Drug repurposing is viewed by some as a faster, cheaper, and less risky approach to drug development. The development of a de novo drug is ...
  89. [89]
    Drug Repurposing – The Saviour of Drug Development?
    Sep 6, 2023 · Moreover, once identified, the chances of DR success exceed novel drug development 3-fold with an estimated 30% approval rate reported for ...
  90. [90]
    Drug Repurposing: An Effective Tool in Modern Drug Discovery - NIH
    Feb 21, 2023 · Repurposing drugs have a significant advantage in decreasing the development cost and time to market over standard discovery. Data like ...
  91. [91]
    Recent advances in drug repositioning and rediscovery for different ...
    Jul 4, 2025 · Most well-known and successful drug repurposing histories, including those involving sildenafil, minoxidil, and aspirin have emerged, often ...<|separator|>
  92. [92]
    Drug Repurposing Strategies, Challenges and Successes
    Mar 4, 2024 · Drug repositioning approaches can focus on identifying promising drugs for repurposing or on a disease state that lacks adequate treatment ...
  93. [93]
    Drug repurposing: a systematic review on root causes, barriers and ...
    Promising drugs are commonly shelved due to insufficient efficacy or superiority to alternate therapies, poor market prospects, and industry consolidation.
  94. [94]
    Drug repurposing: a systematic review on root causes, barriers and ...
    Jul 29, 2022 · Promising drugs are commonly shelved due to insufficient efficacy or superiority to alternate therapies, poor market prospects, and industry consolidation.<|separator|>
  95. [95]
    Drug repurposing for cancer therapy - Nature
    Apr 19, 2024 · Thus, designing innovative strategies to match existing drugs with newfound applications could increase the success of drug repurposing.
  96. [96]
  97. [97]
    [PDF] Adaptive Reuse Challenges and Opportunities in California
    The 1999 Adap- tive Reuse Ordinance in Los Angeles, for example, has been effective in spurring more conversion projects, including the. Broadway Lofts property ...
  98. [98]
    Assessing the environmental benefits of adaptive reuse in historical ...
    Jul 4, 2024 · The outcomes reveal a substantial diminution in environmental impacts, notably an 82% reduction in global warming, 51% smog formation, 27% ...
  99. [99]
    Principles of Adaptive Reuse and World Famous Case Studies
    Oct 11, 2025 · The High Line is an excellent example of adaptive reuse, where an old elevated railway line was transformed into a public park. This project not ...
  100. [100]
    18 "rail-to-trail" projects following in the High Line's footsteps - Dezeen
    Jun 27, 2017 · The Belt Line is designed to occupy a series of abandoned railway corridors to create a route of parks, trails, transit and affordable housing, ...
  101. [101]
    Old train routes are getting recycled into new trail networks
    Nov 27, 2023 · Ryan Chao sees a rare chance to leave a lasting mark by repurposing old, unused infrastructure to create safe, new spaces to walk and bike.<|separator|>
  102. [102]
    Capitalizing on Adaptive Reuse During the Pandemic | Case Studies
    Real estate developer The Estate Companies turned to Holland & Knight's Hotel Conversion and Alternate Use Team to identify, buy and repurpose distressed ...
  103. [103]
    Comparative whole building life cycle assessment of renovation and ...
    The case study showed 53–75% reductions across 6 different environmental impact categories when the renovation was compared to a new construction scenario. The ...
  104. [104]
    COVID-19 critical supplies: the manufacturing repurposing challenge
    For example, a study estimates that over 2,700 manufacturing facilities owned by large firms could be retooled to produce COVID-19 critical items in the US.
  105. [105]
    Repurposing without purpose? Early innovation responses to the ...
    Notwithstanding the need for further research, some repurposed drugs are showing promising initial results as effective treatments for COVID‐19. Remdesivir is a ...
  106. [106]
    UNDP supports innovative solution to 'war waste' in Ukraine
    Jun 11, 2024 · UNDP has been dismantling the rubble from destroyed buildings and introducing a system of waste management.
  107. [107]
    Post-war reconstruction in Ukraine boosted by UK researchers
    Sep 26, 2025 · The reuse of bombed construction materials in Ukraine has been advanced by academics at the University of Leeds, in collaboration with ...Missing: repurposing | Show results with:repurposing
  108. [108]
    Recycling rubble in war-torn Ukraine
    May 16, 2025 · The process involves crushing the rubble, stripping out any steel, textiles or hazardous materials, such as asbestos, and reverse processing it ...
  109. [109]
    Climate Insights 2020: Natural Disasters - Resources for the Future
    Sep 4, 2020 · According to natural scientists, climate change is intensifying natural disasters like wildfires and floods, making them increasingly devastating.
  110. [110]
    Smart Growth Strategies for Disaster Resilience and Recovery - EPA
    These strategies can help communities recover from a disaster, rebuild according to a shared community vision, and be better prepared for the future.Missing: repurposing 2020s
  111. [111]
    The Latest Innovations in Recycling | Busch Systems Blog
    Another recent innovation in recycling is using technology and AI to help sort materials. To help people know which bin to put their items in, AI tools have ...
  112. [112]
    Revolutionizing the circular economy through new technologies
    The results highlight the transformative role of new technologies, especially blockchain and artificial intelligence, in advancing the circular economy.
  113. [113]
    How advanced technologies can help us beat plastic pollution
    Jan 7, 2025 · Smart waste management systems, blockchain-enabled material tracking and advanced recycling methods hold promise but remain far from widespread ...Missing: repurposing | Show results with:repurposing
  114. [114]
    Aeternal Upcycling Turns Plastic Waste into a Resource for New ...
    Aeternal Upcycling has developed a revolutionary chemical recycling technology, catalytic hydrogenolysis, to transform petroleum-based, single-use polyolefins ...
  115. [115]
    Latest Recycling Innovations in 2024
    Apr 9, 2024 · Nanotechnology breaks down materials into their individual molecular parts. Doing this allows engineers to reinforce, improve or repurpose ...
  116. [116]
    Review of polymer technologies for improving the recycling and ...
    This article reviews advancements in polymer technology that aim to improve the efficiency of recycling and upcycling plastic waste.
  117. [117]
    Circular Economy - Environment - European Commission
    The Directive empowering consumers for the green transition from March 2024 ensures that consumers are provided with better information at the point of sale on ...
  118. [118]
    [PDF] Circularity for Secure and Sustainable Products and Materials
    This program funds the development of innovative technologies that include material and product design for circularity, process development, and addressing ...<|separator|>
  119. [119]
    Public Hearing Opened on National Circular Economy Plan | Insights
    Mar 10, 2025 · Axis 2 aims to promote innovation, culture, education, and the development of skills for the reduction, reuse, and promotion of circular ...Missing: repurposing | Show results with:repurposing
  120. [120]
    CGR 2024 - Circularity Gap Report
    This year's report turns theory into action. It lays out a roadmap for ambitious change to unlock capital, roll out bold policies and close the skills gap.
  121. [121]
    [PDF] Circular Transformation of Industries: Unlocking Economic Value
    In a circular economy, products and materials are kept in circulation, resource extraction is slowed down, and economic growth is decoupled from resource.
  122. [122]
    Top 10 Circular Economy Trends in 2025 | StartUs Insights
    Apr 1, 2025 · Discover the Top 10 Circular Economy Trends in 2025, plus 20 out of 2200+ startups in the field, and learn how they impact your business.
  123. [123]
    Global Waste Management Outlook 2024 | UNEP
    Feb 28, 2024 · Municipal solid waste generation is predicted to grow from 2.1 billion tonnes in 2023 to 3.8 billion tonnes by 2050. In 2020, the global direct ...Missing: repurposing | Show results with:repurposing
  124. [124]
    Reaching 2030's residual municipal waste target — why recycling is ...
    Apr 25, 2022 · The 2020 EU circular economy action plan aims to halve the quantity of municipal waste not recycled or prepared for reuse by 2030, while all EU ...Missing: repurposing | Show results with:repurposing
  125. [125]
    The Circularity Gap Report 2025: Why using less is now more urgent
    This year's Circularity Gap Report sends a strong message: we're using more recycled materials, but the demand for raw materials is growing even faster.
  126. [126]
    Circular Economy In Mining: Top 5 Trends For 2025 - Farmonaut
    1. Advanced Resource Recovery Technologies. One of the most impactful circular economy in mining trends for 2025 involves extracting more value from material ...
  127. [127]
    Challenges and opportunities for scaling up upcycling businesses
    Upcycling is a process in which products and materials that are no longer in use, or are about to be disposed, are instead repurposed, repaired, upgraded and ...Missing: early | Show results with:early<|separator|>
  128. [128]
    [PDF] Challenges and success factors for scaling up an upcycling ... - DiVA
    Similar to the woodworking sector, the uncertainty surrounding the availability of textile materials poses a challenge to relying solely on repurposed materials ...
  129. [129]
    Emerging Trends in the Circular Economy: Multidimensional ...
    Mar 27, 2025 · Circular processes like material reuse and remanufacturing make supply networks more robust by minimising reliance on finite raw resources, ...
  130. [130]
    Challenges and opportunities for scaling up global upcycling ...
    Challenges and opportunities for scaling up global upcycling towards sustainable production and consumption: Literature review. June 2021. Authors: Kyungeun ...
  131. [131]
    [PDF] Scale Up This? Improving Scalability and Viability in Upcycling Design
    However, craft production methods common to the repurposing approach of most upcycling enterprises hinder their ability to scale up. This thesis aims to assist ...