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Manufacturing execution system

A Manufacturing Execution System () is a software platform that monitors, manages, and optimizes manufacturing operations on the shop floor, bridging the gap between high-level () systems and low-level control systems to ensure efficient production execution. Developed to address the need for seamless integration in complex manufacturing environments, MES provides visibility into production processes, enabling data-driven decisions that enhance productivity and . The foundational framework for MES is outlined in the ISA-95 standard (also known as ANSI/ISA-95 or IEC 62264), an international guideline established by the for integrating enterprise and control systems across manufacturing hierarchies. This standard positions at Level 3 of the , where it handles production scheduling, execution, and performance monitoring between business planning (Level 4) and process control (Level 2). Building on earlier models from MESA International, ISA-95 incorporates the MESA-11 framework, which defines 11 core functions essential to MES capabilities, ensuring standardized interoperability with , , and technologies. These 11 core functions, as delineated by the MESA-11 model, encompass critical operational areas including: By implementing MES, manufacturers achieve enhanced , reduced costs, and improved with regulatory standards, making it indispensable for industries like automotive, pharmaceuticals, and where and are paramount.

Introduction

Definition and Scope

A manufacturing execution (MES) is a computerized designed to and document the transformation of raw materials into through monitoring and control of processes on the shop floor. According to the ISA-95 standard, MES operates at Level 3 of the enterprise-control model, focusing on manufacturing operations management to execute planned activities efficiently. Its core purpose is to bridge the gap between (ERP) s at the business planning level (Level 4) and shop floor control s (Levels 0-2), thereby optimizing efficiency by providing seamless data flow and operational insights. The scope of an MES encompasses key shop floor activities, including the , , and synchronization of manufacturing processes across discrete, continuous, and batch operations. It distinguishes itself from broader supervisory and (SCADA) systems, which primarily focus on and of physical processes, by emphasizing higher-level such as execution and . Unlike narrower tools that handle specific machinery , MES provides an integrated view of the entire , ensuring alignment with business objectives without extending into enterprise-wide planning or low-level device . Key characteristics of MES include real-time data visibility, which enables immediate detection of production variances; decision support through analytics and alerts for proactive adjustments; and compliance with production standards to meet regulatory and quality requirements. These features, framed by models like ISA-95, support enhanced operational agility and reduced downtime in manufacturing environments.

Historical Evolution

The concept of Manufacturing Execution Systems () emerged in the early 1990s as an intermediate layer bridging () systems at the enterprise level and process systems on the shop floor, enabling and of operations. The term "" was coined by AMR Research in 1990 to describe software solutions that addressed the growing need for operational visibility in complex environments. Initially focused on sectors like automotive and , these systems evolved from basic tools to more comprehensive platforms that integrated production scheduling, , and . In 1992, the Manufacturing Enterprise Solutions Association (MESA) was formed as a nonprofit organization to promote MES adoption and standardize its functionalities. MESA published the original MESA-11 model in 1996, defining 11 core functions that guided early implementations. MESA's efforts helped address the fragmentation in manufacturing IT, fostering collaboration among vendors, integrators, and users to refine MES models for better interoperability. A pivotal milestone came with the introduction of the ANSI/ISA-95 standard in 2000 by the International Society of Automation (ISA), which provided a hierarchical framework for enterprise-control system integration, including models for manufacturing operations management. This standard underwent refinements, with an update to Part 1 in 2010 emphasizing object models and activity hierarchies, Part 3 first published in 2005 and revised in 2013 to detail workflow models for production operations, and a further update to Part 1 in 2025 addressing IT/OT convergence. The ISA-95 framework, which briefly references standardized functional areas like resource management and data collection, became the de facto reference for MES design across industries. Over the subsequent decades, MES transitioned from standalone, on-premises systems tailored primarily to to highly integrated platforms that connected with broader enterprise ecosystems, including and analytics tools. This shift facilitated expansion into process industries such as pharmaceuticals and chemicals, where MES supported batch tracking and alongside traditional . In the and 2020s, driven by initiatives like Industry 4.0, MES evolved toward cloud-based and modular architectures, allowing scalable deployment, remote access, and seamless integration with devices and for . These advancements reduced implementation costs and enabled smaller manufacturers to adopt MES without heavy upfront investments, marking a broader democratization of technologies.

System Components and Architecture

Key Components

A Manufacturing Execution System (MES) consists of interconnected hardware, software, and human elements designed to facilitate real-time monitoring and control on the shop floor, as outlined in the ISA-95 standard for -control . These components work together to bridge operations with higher-level systems, ensuring efficient data flow and operational visibility. Software modules form the core of an MES, encompassing applications for real-time monitoring, intuitive user interfaces, and robust databases. Real-time monitoring applications track production processes, equipment performance, and workflow status, enabling immediate detection of deviations and adjustments. User interfaces, often graphical and web-based, provide dashboards for visualizing key performance indicators and entering operational data. Databases, typically relational structures like SQL-based systems, store and query production metrics, historical logs, and configuration data to support analytics and reporting. These modules are standardized in ISA-95 Part 3 for activity models and Part 4 for object models that define data attributes for consistent software interoperability. Hardware elements integrate physical devices for data input and output, including sensors, programmable logic controllers (PLCs), and servers. Sensors, such as probes and proximity detectors, capture environmental and process data from the . PLCs serve as supervisory controls, executing automated commands and relaying updates to the software at Level 3 of the ISA-95 . Servers, often industrial-grade with , host the applications and process data streams from field devices, ensuring low-latency communication in harsh manufacturing environments. Human components emphasize operator interaction through interfaces, role-based access controls, and workflow tools tailored for personnel. interfaces, including human-machine interfaces (HMIs) and applications, deliver contextual guidance and allow overrides or confirmations during production. Role-based access ensures that supervisors, technicians, and operators view only relevant data and perform authorized actions, reducing errors and enhancing accountability. Workflow tools guide personnel through tasks via digital instructions and escalation protocols, integrating human decision-making with automated processes as per ISA-95's manufacturing operations management models. Data management in an MES relies on centralized repositories to handle production information, utilizing relational databases and application programming interfaces () for seamless connectivity. Centralized repositories aggregate real-time and historical from multiple sources, enabling unified access for and . Relational databases organize structured like work orders and inventory levels, while facilitate integration with external systems for bidirectional exchange. This structure, defined in ISA-95 Parts 2 and 5, supports transactions between manufacturing and business activities, ensuring integrity and timeliness. Security features in an MES protect sensitive operational data through authentication, encryption, and audit trails adapted to manufacturing settings. Authentication mechanisms, such as multi-factor and role-based logins, verify user identities to prevent unauthorized access to control functions. Encryption secures and at rest, using protocols like TLS for communications between devices and servers. Audit trails log all system events, including user actions and data changes, providing tamper-evident records for and incident investigation in high-stakes environments. These elements align with ISA-95's emphasis on secure in operations management.

Architectural Models

The architectural models of Manufacturing Execution Systems (MES) are fundamentally shaped by the (PERA), a reference framework developed in the early 1990s to guide enterprise integration in . PERA organizes operations into a hierarchical structure with multiple levels, positioning MES specifically at Level 3, which focuses on manufacturing operations management and workflow coordination between enterprise planning and shop-floor execution. This placement enables MES to bridge higher-level (ERP) systems at Level 4 with lower-level process control systems at Levels 0-2. The International Society of Automation's ISA-95 standard builds directly on this PERA hierarchy to define models for enterprise-control system integration in MES deployments. A prevalent in MES is the client-server paradigm, where centralized servers handle core processing, , and , while distributed clients on the shop floor interface with equipment and operators for real-time monitoring and input. This setup enhances by allowing additional clients to connect without overhauling the central infrastructure, supporting growth in manufacturing facilities from small-scale to enterprise-wide operations. For instance, MES servers are often sized and configured to manage varying loads through horizontal , such as clustering multiple servers for high-availability environments. Modern MES architectures increasingly adopt a , featuring plug-and-play components that allow for tailored customization to specific production needs. These modules, such as those for , , or , can be independently developed, tested, and integrated, reducing deployment complexity and enabling rapid updates. In contemporary implementations, this extends to architectures, where discrete services communicate via APIs to decompose monolithic systems into scalable, resilient units, as demonstrated in event-driven refactoring approaches for legacy MES. Data flow models in MES emphasize bidirectional communication layers to ensure seamless across the ecosystem. Upward flows transmit data, such as performance metrics and updates, from the shop floor to ERP systems for strategic planning, while downward flows deliver instructions, schedules, and recipes from ERP to control systems for execution. This layered approach, often implemented through standardized interfaces like those in ISA-95, maintains and supports closed-loop control in dynamic environments. Scalability in MES architectures is addressed through flexible deployment options, evolving from traditional on-premise installations—where all components reside in local data centers for controlled environments—to -hybrid models that combine on-site processing with -based and . setups provide elasticity for handling peak loads via resources while retaining sensitive operations on-premise, thus optimizing cost, performance, and compliance in diverse manufacturing scales. For example, MES enables incremental migration, allowing manufacturers to scale computational resources dynamically without full system overhauls.

Functional Areas

Resource and Production Management

In manufacturing execution systems (MES), resource management encompasses the allocation and optimization of personnel, equipment, and materials to ensure efficient production operations at Level 3 of the enterprise-control hierarchy. As defined in ANSI/ISA-95.00.03-2013 (Part 3), this function involves tracking resource capabilities, availability, and status to assign them effectively to production tasks, preventing bottlenecks and supporting overall manufacturing objectives. Personnel allocation considers skills, certifications, and shift schedules; equipment assignment accounts for maintenance status and capacity limits; and material distribution relies on inventory visibility and just-in-time principles to minimize waste. This structured approach, integral to ISA-95's manufacturing operations management (MOM) models, facilitates seamless integration with higher-level enterprise resource planning (ERP) systems for resource forecasting and utilization. Production scheduling in MES focuses on sequencing jobs, capacity planning, and generating feasible production timelines that align manufacturing processes with business goals. ANSI/ISA-95.00.03-2013 specifies activity models for this function, enabling the creation of detailed schedules that incorporate constraints such as resource availability and order priorities. Common approaches include finite scheduling, which respects limited resource capacities to avoid overloads, and infinite scheduling, which assumes unlimited capacity for initial planning before refinement. Algorithms for job sequencing often prioritize factors like due dates, setup times, and throughput optimization, using techniques such as priority dispatching rules or heuristic methods to balance efficiency and flexibility in dynamic environments. These models ensure that schedules are executable and adaptable, supporting real-time updates based on production feedback. Dispatching and execution management in MES involve issuing work orders, coordinating resource deployment, and monitoring to drive production forward. Under ISA-95 Part 3, dispatching assigns specific tasks to personnel and via detailed instructions derived from the production schedule, while execution oversees the step-by-step progression of orders, enabling adjustments for disruptions like failures or material shortages. This process tracks progress against planned timelines and quantities, ensuring completion rates align with targets and facilitating order closure upon fulfillment. Effective execution relies on standardized workflows that integrate with control systems for automated triggering of operations. Product definition management in MES handles the configuration of production requirements through bills of materials (BOM), recipes, and routing definitions to guide processes. ANSI/ISA-95.00.04-2018 (Part 4) provides object models and attributes for these elements, standardizing their representation for consistent data exchange between and control systems. A BOM outlines the hierarchical structure of components and quantities needed for an assembly; recipes specify process parameters, such as mixing ratios or temperature controls in ; and routings define the sequence of operations, including workstations and tools required. These definitions ensure that production orders are accurately interpreted and executed, supporting variability in product variants while maintaining compliance with specifications.

Data Collection and Analysis

In manufacturing execution systems (MES), data collection and analysis form two core functions as defined by the ISA-95 standard, enabling the capture of information and its evaluation to optimize operations. The function focuses on acquiring operational data from processes, while performance analysis processes this data to generate insights into efficiency and productivity. These functions support decision-making at Level 3 of the ISA-95 hierarchy by bridging shop-floor activities with higher-level systems. Data acquisition in MES occurs through real-time interfaces with sensors, programmable logic controllers (PLCs), distributed control systems (DCS), and human-machine interfaces (HMIs), allowing continuous monitoring of machine states, process parameters, and operator inputs. For instance, sensors on production equipment capture variables such as temperature, pressure, and throughput rates, which are aggregated via protocols like OPC UA or to ensure low-latency data flow. Operator interfaces, often integrated with barcode scanners or RFID systems, contribute manual entries for events like setup changes or , ensuring comprehensive coverage of both automated and human-driven activities. Production performance analysis leverages collected data to compute key metrics that quantify manufacturing efficiency. (OEE), a primary indicator, is calculated as the product of (uptime ratio), performance (speed efficiency), and quality (defect-free output rate), providing a holistic view of asset utilization. Other metrics include cycle times, which measure the duration of individual production steps, and yield rates, assessing the proportion of usable products from raw inputs. These analyses align with ISA-95's emphasis on evaluating resource utilization and process outcomes to identify bottlenecks. Reporting tools in MES transform raw and analyzed data into actionable formats, including interactive dashboards that visualize key performance indicators (KPIs) such as OEE trends and throughput variances. Historical data trending capabilities enable long-term , often using time-series databases to plot metrics over shifts, days, or months for comparative analysis. These tools facilitate custom reports in formats like B2MML XML for with systems, supporting proactive adjustments to schedules. Anomaly detection within MES employs basic statistical methods to identify deviations from expected norms, enhancing performance analysis by flagging potential issues early. Techniques such as statistical profiling establish baseline distributions of process variables (e.g., and deviation of cycle times) and detect outliers using thresholds like z-scores, where values exceeding three deviations signal anomalies. Control charts, a common method, monitor metrics like yield rates over time to distinguish common cause variations from special causes requiring intervention. In practice, these approaches integrate with streams to alert operators to irregularities, such as unexpected spikes, thereby minimizing disruptions.

Quality and Traceability

Manufacturing execution systems () play a critical role in by facilitating in-process inspections, defect tracking, and integration with () tools to monitor and maintain production standards. In-process inspections within involve real-time verification of product attributes during manufacturing, such as dimensional checks or functional tests, to detect deviations early and prevent defective outputs from progressing. Defect tracking capabilities allow to log nonconformances, assign corrective actions, and route items for rework or , ensuring systematic and reducing variability in production. Integration with enables to analyze process data for trends, control limits, and indices, supporting proactive adjustments to uphold thresholds. Traceability in MES ensures end-to-end visibility of product lineage through genealogy tracking, serial number management, and lot/batch control, enabling precise recall and root-cause analysis if issues arise. Genealogy records the complete history of a product, including raw materials, processing steps, equipment used, and personnel involved, forming a digital thread from input to output. Serial number tracking applies to discrete items, assigning unique identifiers for individual unit monitoring, while lot/batch management groups similar units under a shared identifier for collective quality assessment, often involving representative sampling. These features support compliance with regulatory demands by providing auditable records of material flows and transformations. Document control in MES encompasses electronic work instructions and compliance records to standardize operations and maintain evidentiary support for quality assurance. Electronic work instructions deliver dynamic, context-aware guidance to operators via digital interfaces, incorporating from production execution to minimize errors and ensure adherence to procedures. Compliance records, stored centrally within the MES, include results, logs, and trails, facilitating rapid retrieval during reviews. This centralized approach reduces paperwork, enhances accuracy, and aligns with interfaces defined in manufacturing standards. Under the ISA-95 standard, MES functions for and are outlined in models of , particularly through production activities that integrate with and operations. Part 3 of ISA-95 details activity models for tracking production progress, material usage, and events, enabling seamless data exchange between (Level 3) and enterprise systems. These models support interfaces for testing, nonconformance reporting, and historical data retrieval, ensuring cohesive . Part 5 further specifies transactions for information, such as queries for product history and updates on status. MES supports in industries like pharmaceuticals and s by generating reports that meet standards such as FDA 21 CFR Part 820 for quality systems and for quality management. For FDA compliance, MES maintains electronic device history records (eDHR) with full audit trails and secure , aligning with current good manufacturing practices (cGMP) for from raw materials to finished goods. requires documented procedures for , particularly for implantable devices, where MES ensures identification and tracking throughout the to support post-market surveillance and recalls. These capabilities help manufacturers demonstrate conformance during audits by providing verifiable, tamper-evident records.

System Integration

With Enterprise Systems (Level 4)

Manufacturing execution systems (MES) integrate with (ERP) systems at ISA-95 Level 4 to bridge manufacturing operations with business planning and . This upward integration enables seamless data flow between shop floor execution and higher-level functions, such as and financial reporting. A primary aspect of this integration involves bidirectional exchange, where systems upload production schedules, work orders, and material requirements to the for execution, while the MES reports back actual production outcomes, including costs, yields, and levels. This ensures that enterprise-level decisions are informed by operational realities, reducing discrepancies between planned and actual performance. For instance, actual consumption from the MES updates ERP records, preventing overstocking or shortages. Workflow synchronization aligns business orders from the with shop floor activities in the , ensuring that sales orders translate directly into executable tasks without manual intervention. Key protocols facilitating this include application programming interfaces () for direct connectivity, XML-based messaging, and such as Business to Manufacturing Markup Language (B2MML), which supports ISA-95 compliant data models for standardized exchange. These mechanisms enable automated handoffs, such as converting ERP purchase orders into MES dispatch lists. In practice, MES-ERP integration enhances by providing granular data to ERP analytics, allowing for more precise predictions of market needs and . It also improves financial accuracy through timely reporting of variances in labor, materials, and overhead costs, minimizing errors in budgeting and profitability assessments. For example, integration with supports end-to-end order-to-cash processes by linking confirmations to invoicing and . Similarly, Oracle ERP integrations, often via Oracle MES for , streamline work order fulfillment and inventory tracking in discrete environments.

With Control Systems (Levels 0-2)

Manufacturing execution systems () at ISA-95 Level 3 integrate closely with lower-level control systems to enable oversight and coordination of production processes. This integration facilitates bidirectional data exchange between MES and the automation layers defined in the ISA-95 standard, which structures manufacturing hierarchies from physical processes (Level 0) to supervisory control (Level 2). By interfacing with these levels, MES ensures that production instructions align with operational realities on the shop floor, supporting efficient execution while maintaining and responsiveness. Downward communication from MES to control systems involves transmitting operational directives such as setpoints, production recipes, and workflow instructions to programmable logic controllers (PLCs) and supervisory control and data acquisition () systems. For instance, MES can download recipe parameters—including material specifications, process parameters, and sequencing—to PLCs for automated execution, ensuring consistency in batch or continuous manufacturing. This flow supports dynamic adjustments to production runs based on higher-level scheduling, with MES verifying command acknowledgment before proceeding. Upward data flow conversely captures real-time information from devices, including readings, machine status updates, and parameters, which aggregates for analysis and decision-making. at Level 1 provide on variables like or , while Level 2 systems (e.g., PLCs) compile supervisory metrics such as utilization or cycle times. This enables to monitor performance against planned outputs, feeding into broader production management without delving into detailed execution data. Common protocols for this real-time connectivity include OPC UA, , and , which standardize data exchange across heterogeneous devices. OPC UA, in particular, supports secure, platform-independent communication for both upward and downward commands, mapping ISA-95 object models like equipment and material definitions to enable seamless . These protocols operate at Levels 0-2, where Level 0 handles physical process interfaces, Level 1 manages sensing and actuation, and Level 2 provides supervisory control, all interfacing with for coordinated operations. Performance evaluations confirm their suitability for environments, with OPC UA offering robust for complex integrations. Error handling in these integrations relies on feedback loops and alarm mechanisms to detect and mitigate discrepancies. When a setpoint or command is issued downward, control systems return status confirmations or error codes to MES, triggering adjustments such as recipe revisions or production halts if deviations exceed thresholds. Alarms from Level 2 systems propagate upward to MES for immediate alerting, enabling rapid response to issues like equipment faults or anomalies, thus minimizing and ensuring compliance with operational standards.

With Other Manufacturing Systems (Level 3)

Manufacturing execution systems () at ISA-95 Level 3 facilitate horizontal integrations with other manufacturing (MOM) systems to enable coordinated oversight of , , , and activities. These integrations occur among peer systems within Level 3, supporting standardized data exchanges for personnel, equipment, materials, and physical assets to achieve holistic . By leveraging common object models defined in ISA-95, such as those for material properties, equipment roles, and , ensures seamless without relying on vertical connections to higher enterprise layers. A key collaboration exists between MES and laboratory information management systems (LIMS) for quality testing and validation processes. MES transmits production data, including batch details and sample requirements, to LIMS, which performs analyses and returns results to inform release decisions. This bi-directional flow enhances traceability and compliance, with LIMS providing quality metrics like test outcomes and deviations back to MES for real-time adjustments. Similarly, MES integrates with warehouse management systems (WMS) to synchronize and flows, where MES signals needs based on production schedules, and WMS responds with , storage locations, and transport confirmations. For maintenance, MES collaborates with computerized maintenance management systems (CMMS) to manage equipment downtime, sharing operational data to trigger preventive actions while receiving updates on repair statuses. Data sharing across these systems is foundational to . From LIMS, receives quality results such as analytical test data and certifications, enabling automated batch disposition and reducing manual errors by up to 70%. WMS contributes material movement records, including lot tracking and inventory levels, allowing to optimize production sequencing and minimize stockouts through visibility. CMMS supplies asset health indicators, such as vibration metrics or failure predictions, which uses to adjust workloads and prevent unplanned interruptions. These exchanges, governed by ISA-95 messaging services, ensure consistent data formats for retrieval, transfer, and storage across MOM applications. In practice, these integrations manifest in scenarios like synchronizing schedules to avoid production conflicts; for instance, monitors equipment usage in and coordinates with CMMS to schedule repairs during low-utilization windows, such as basing interventions on cycle counts rather than fixed calendars. This approach aligns with demands, reducing by integrating predictive alerts from into CMMS workflows. Multi-system environments require robust mechanisms, often implemented through rules embedded in . These rules evaluate factors like urgency, criticality, and resource availability to resolve overlaps, such as competing demands for shared assets between and tasks. Automated orchestration in integrated setups assigns priorities dynamically, ensuring minimal disruptions—for example, deferring non-critical WMS transfers if detects a high-priority run. Such strategies, aligned with ISA-95's emphasis on coordinated MOM functions, promote resilient operations.

Benefits and Challenges

Operational Benefits

Manufacturing execution systems (MES) enhance operational visibility by providing real-time monitoring of activities, allowing managers to track production status, equipment performance, and bottlenecks instantaneously. This enables proactive decision-making, such as reallocating resources during disruptions, which minimizes unplanned and operational errors. According to the ISA-95 framework, such visibility supports detailed insights into cycle times, yields, and throughput, fostering better coordination between production teams. Efficiency gains from arise through precise control over production processes, including automated scheduling and optimization, which reduce cycle times, scrap rates, and the need for rework. For instance, facilitates consistent operator performance and process repeatability, stabilizing operations and accelerating continuous improvement efforts aligned with methodologies like and . In practice, these capabilities stem from integrated functional areas such as and , enabling streamlined execution without delving into their specifics. Case studies demonstrate tangible outcomes, such as a productivity increase from 250 to 350 units per day in a molding operation following deployment. Traceability enhancements in create comprehensive audit trails for materials, products, and processes, ensuring full from raw inputs to and enabling rapid root-cause analysis for quality issues. This feature supports and quick resolution of defects, reducing investigation times from days to hours in complex manufacturing environments. As outlined by MESA International, digitized records and bolster integrity and operational accountability. Uptime improvements are achieved through better resource utilization and predictive alerts generated from real-time equipment data, allowing maintenance teams to address potential failures before they occur. MES monitors machine health and faults continuously, minimizing idle time and optimizing (OEE). In a printing industry , real-time monitoring via an -like system improved (OEE) by 15% and increased availability from 75% to 86.85%. Quantifiable metrics from various implementations show OEE uplifts of 10-20%, as seen in scenarios where integrated and solutions drove these gains.

Implementation Challenges

Implementing a Manufacturing Execution System () often encounters significant complexities, particularly with systems that lack standardized formats and protocols. These challenges arise because many facilities operate on disparate systems developed by different vendors, requiring extensive or custom interfaces to ensure seamless flow between , (ERP) systems, and shop-floor controls. For instance, differing structures can lead to formatting issues during interfacing, complicating real-time synchronization and increasing error risks. systems, frequently built on outdated technologies, exacerbate compatibility problems, as they may not support modern or cloud-based architectures, necessitating costly upgrades or efforts. Cost factors represent another major barrier, encompassing high initial setup expenses for , software licensing, and , alongside ongoing investments in and . Initial implementation costs can start at $500,000 for the software alone, with additional expenditures for validation and process reengineering comprising significant portions of total costs, driven by the need to adapt legacy infrastructure. Ongoing , including annual software support typically around 15-20% of the purchase price, further strains budgets, particularly for small- to medium-sized enterprises where resource constraints amplify financial pressures. Organizational hurdles, including , user adoption, and skill gaps on the shop floor, frequently undermine MES deployments. Resistance to change stems from disruptions to established workflows, with employees wary of increased monitoring and new interfaces, leading to low adoption rates if not addressed through targeted and . Skill gaps among operators, often lacking familiarity with digital tools, require comprehensive upskilling programs, while cultural differences in multi-site operations can hinder consistent buy-in across teams. Effective , involving clear communication of benefits and super-user networks, is essential to foster acceptance. Scalability risks during rollout demand careful strategy selection, with phased approaches generally preferred over big-bang implementations to mitigate disruptions. Phased rollouts, starting with pilot sites, allow iterative testing and adjustment, achieving higher success rates though they extend timelines compared to big-bang strategies, which can realize quicker initial gains but carry higher failure risks due to overwhelming complexity in diverse environments. Architectural choices, such as modular designs, can ease by enabling incremental expansion without full system overhauls. Measuring (ROI) for MES poses challenges due to variable timelines and pitfalls like over-customization, which can inflate costs and delay benefits. Typical ROI realization occurs within 12-24 months for successful projects, with periods often 12-24 months through reductions in cycle time and efforts. However, over-customization often leads to maintenance burdens that erode gains, while indirect benefits like improved are harder to quantify, necessitating standardized KPIs focused on throughput and metrics to track progress accurately. As of 2025, emerging challenges include cybersecurity risks in cloud-based MES integrations.

Standards and Best Practices

ISA-95 Standard

The ISA-95 standard, formally known as ANSI/ISA-95 or IEC 62264 internationally, serves as a foundational framework for integrating enterprise systems with manufacturing control systems, building on the Purdue Enterprise Reference Architecture (PERA) model to define hierarchical levels from process control (Levels 0-2) to manufacturing operations (Level 3) and business planning (Level 4). Initially published in 2000, the standard was updated through subsequent parts between 2005 and 2013, with further revisions extending to 2025, including an update to Part 1 in April 2025. It provides standardized models, terminology, and interfaces to enable consistent data exchange between manufacturing execution systems (MES) at Level 3 and enterprise resource planning (ERP) systems at Level 4, without prescribing specific technologies. The structure of ISA-95 is organized into multiple parts, with the core five parts establishing comprehensive models for key manufacturing elements. Part 1 outlines models and terminology for the overall scope, including functional hierarchies and information flows. Part 2 defines object models and attributes for the between and systems, focusing on consistent representation. Part 3 details activity models for operations management, describing workflows and interactions. Part 4 provides object models and attributes specifically for operations, covering internal Level 3 functions. Part 5 specifies transactions and messages between business and functions, enabling practical exchanges. These parts collectively model activities (e.g., workflows), (e.g., asset hierarchies), personnel (e.g., assignments), (e.g., tracking), and (e.g., scheduling and execution). The 2025 update to Part 1 includes changes to reflect specific functions in the and highlight the boundary between and systems. Central to ISA-95's framework in Part 3 are 11 functional areas that define the scope of operations management (MOM) activities at Level 3, providing a for MES capabilities and ensuring alignment with goals. These originate from the MESA-11 model incorporated into the standard:
  • Resource Allocation and Status: Manages the availability and assignment of , personnel, and materials to activities, tracking updates.
  • Operations/Detail Scheduling: Develops detailed schedules from high-level plans, optimizing resource use and sequencing work orders.
  • Dispatching Production Units: Issues work instructions and sequences to lines or units, coordinating start, stop, and progression of tasks.
  • Document Control: Handles the creation, distribution, and of -related documents, such as , procedures, and specifications.
  • Data Collection/Acquisition: Gathers and historical from shop-floor devices and processes, ensuring accurate capture of and metrics.
  • Labor Management: Tracks personnel assignments, time, skills, and performance, integrating with scheduling for efficient workforce utilization.
  • Quality Management: Oversees quality tests, inspections, and compliance checks throughout , linking results to process adjustments.
  • Process Management: Defines, monitors, and controls processes, including management and enforcement.
  • Maintenance Management: Schedules preventive and corrective for , integrating with to minimize .
  • Product Tracking and Genealogy: Monitors material and product movement through the facility, recording lineage for and recall purposes.
  • Performance Analysis: Analyzes to generate reports on efficiency, throughput, and key performance indicators, supporting continuous improvement.
Implementation guidance in ISA-95 emphasizes practical tools for system developers and integrators, including hierarchical object models in Parts 2 and 4 that represent entities like equipment and personnel classes with defined attributes for . Activity models in Part 3 use hierarchical diagrams to depict MOM processes, facilitating requirements definition and . Additionally, interface standards such as B2MML (Business to Manufacturing Markup Language), an based on Part 5, provide a standardized format for exchanging production schedules, status updates, and work orders between and systems. Globally, ISA-95 has seen widespread adoption as the reference for scoping MES functionalities and promoting across diverse sectors, with surveys indicating over 90% usage among manufacturers and solution providers for enterprise-control integrations. Its models have become essential for reducing custom integration efforts and aligning IT/ systems in , , and batch environments. In the context of Industry 4.0, have evolved as a foundational pillar for smart factories, integrating with the and to enable real-time data collection, analysis, and decision-making. This integration allows to bridge physical production processes with digital models, fostering proactive environments through big data analytics and , as demonstrated in sectors like automotive and pharmaceuticals where facilitates seamless across devices and systems. By leveraging sensors, enhances operational visibility and responsiveness, transforming traditional factories into interconnected ecosystems capable of adapting to dynamic production demands. Advancements in (AI) and (ML) have further enhanced capabilities, particularly through for maintenance and optimization, including algorithms that analyze equipment data in . These technologies enable to forecast potential failures using IoT-generated data, reducing machine downtime by up to 50% and extending equipment life. In practice, ML models integrated into process patterns from cycle times and energy usage to preempt issues, supporting fault detection and production optimization in high-volume manufacturing. The shift toward cloud and has introduced software-as-a-service () MES models, providing greater flexibility, scalability, and remote access for manufacturers, especially small and medium-sized enterprises (SMEs). Cloud-based MES, often hosted on platforms like , allow real-time process management from any location, bridging gaps between MES and (ERP) systems while improving uptime and productivity in flexible manufacturing scenarios. Complementing this, processes data closer to the source, minimizing for immediate insights and enhancing MES in distributed environments. Post-2020 deployments of MES have increasingly incorporated sustainability features, such as energy tracking and waste reduction, to align with environmental regulations and corporate goals for lowering greenhouse gas emissions. By monitoring energy consumption against standards like those from the Department of Energy (DOE) and optimizing material use, MES can achieve up to 30% reductions in energy and costs through data-driven process improvements. These systems identify inefficiencies and waste in production, enabling targeted actions that minimize environmental impact while integrating with AI and digital tools for enhanced resource efficiency. Emerging trends in MES include the adoption of digital twins for virtual simulation and real-time synchronization with physical operations, blockchain for secure traceability, and convergence with Industrial IoT (IIoT) for scalable connectivity. Digital twins within MES support predictive maintenance and autonomous adjustments via AI, as seen in Industry 4.0 testbeds involving robotic systems synchronized through protocols like OPC UA. Blockchain enhances data integrity for supply chain tracking, while IIoT integration via edge AI and 5G enables low-latency communication, driving self-learning factories and resilient manufacturing networks.

References

  1. [1]
    ISA-95 Series of Standards: Enterprise-Control System Integration
    ISA-95, also known as ANSI/ISA-95 or IEC 62264, is an international set of standards aimed at integrating logistics systems with manufacturing control systems.
  2. [2]
    ISA-95 framework and layers | Siemens Software
    ISA-95 is an international standard for integrating enterprise and control systems, organized into layers that span physical processes to business-related ...What Are Isa 95 Framework &... · Understand The Benefits · Efficient Workflow...
  3. [3]
    What is a Manufacturing Execution System | MES blog - Infor
    Jul 24, 2023 · In the ISA-95* model that defines the integration of business and manufacturing processes, MES is the functional layer (level 3). Each level ...
  4. [4]
    History of the MESA Models - Manufacturing Enterprise Solutions ...
    This model indicated 11 core functions of a manufacturing execution system with relationships to external enterprise systems and functional areas. This model ...
  5. [5]
    MES, ISA-95, MESA-11, cMES, NAMUR – Why So Many Standards?
    Apr 9, 2025 · The ISA-95 model divides production systems into 5 levels, based on the Purdue Enterprise Reference Architecture (PERA) model.
  6. [6]
    What is an manufacturing execution system (MES)? - SAP
    A manufacturing execution system (MES) is a software application that helps businesses more efficiently manage their manufacturing operations.Manufacturing Execution... · Top Five Benefits Of Mes · Core Mes Features
  7. [7]
    What is manufacturing execution system (MES)? - TechTarget
    Oct 27, 2023 · A manufacturing execution system (MES) is an information system that connects, monitors and controls complex manufacturing systems and data flows on the ...<|control11|><|separator|>
  8. [8]
    What is a Manufacturing Execution System (MES)? - IBM
    A manufacturing execution system (MES) is a software-based solution used in manufacturing to monitor and control production processes on the shop floor.<|control11|><|separator|>
  9. [9]
    History of MES – Manufacturing Execution System
    Sep 8, 2021 · The name MES was created by the company AMR Research in 1990 and 1992 a group of software development, consultants, and solution integrators ...
  10. [10]
    MES 101: What is a Manufacturing Execution System - PINpoint MES
    By the early 1990s, the term “MES” became widely used to describe systems that controlled real-time factory operations. In 1997, the Manufacturing Enterprise ...
  11. [11]
    MES History And Evolution: From PLCs To Industry 4.0
    Integration with Enterprise Systems: MES in the 1990s · MES emerged as the bridge between ERP and shop floor systems like PLCs, SCADA, and DCS. · It provided real ...<|separator|>
  12. [12]
    [PDF] ISA 95 compatible MES
    Oct 30, 2024 · ISA-95 was first released in 2000 by the International Society of Automation (ISA) to provide a common framework for integrating enterprise ...
  13. [13]
  14. [14]
    Understanding Manufacturing Execution Systems (MES) in Discrete ...
    Feb 23, 2024 · The role of MES in discrete manufacturing is set to expand further with the advent of Industry 4.0 and the Internet of Things (IoT). These ...
  15. [15]
    Cloud MES: How manufacturing software is migrating to the cloud
    Mar 3, 2021 · The preferred method of migrating MES to the cloud depends on multiple factors such as capital investment, operational expenses, scalability, ...Missing: 2010s 2020s sources
  16. [16]
    Cloud-Based MES: The Effort to Empower Small Manufacturers
    Yet, many of today's advances in manufacturing technology, like the cloud-based MES (Manufacturing Execution System) are making it possible for small and medium ...
  17. [17]
    Subscription MES: A New Path to Digital Transformation - IIoT World
    Jun 26, 2025 · Discover how subscription-based MES offers faster ROI, modular deployment, and scalable digital transformation for modern manufacturers.Missing: cloud- 2010s 2020s
  18. [18]
    MES - Manufacturing Execution System - Industry Software
    Human-Machine Interfaces (HMI). Provide operators with intuitive dashboards and mobile access for monitoring and controlling production processes from anywhere.
  19. [19]
    MES Architecture: The Backbone of Modern Manufacturing
    At the bottom, MES communicates with shop floor systems and hardware. This includes PLCs, HMIs, barcode scanners, vision systems, RFID tags, torque tools, and ...
  20. [20]
    The Role of Industrial Servers in SCADA and MES Systems
    Discover how industrial servers support SCADA and MES systems, enhancing real-time monitoring, control, and data management in industrial environments.
  21. [21]
  22. [22]
    Top 10 Security Requirements for a MES System
    Mar 25, 2024 · Top MES security requirements include access control, data encryption, data integrity, backups, and network security.Missing: trails | Show results with:trails
  23. [23]
    MES Challenges and Considerations: Data Management and Security
    Encrypt sensitive data and maintain audit trails aligned with regulations. Backup and Recovery, Automate regular backups and simulate disaster recovery drills.
  24. [24]
  25. [25]
    The 11 main functions of an MES software - META 2i
    Personnel management · Quality management · Product and batch tracking · Maintenance management · Data collection and acquisition · Scheduling · Process management.
  26. [26]
    [PDF] Practical Applications of the ISA 95 standard
    • Introduction to ISA 95 & MES. • Advantages of the ISA95 standard. • Most ... • USA ANSI standard developed by an ISA Committee of volunteer experts.
  27. [27]
    The 11 functions of MES - ISA95 standard - CT INFODREAM
    The 11 functions of the MES (Manufacturing Execution System) are defined by ISA95. This standard makes it possible to delimit the common coverage imposed on ...
  28. [28]
    The Role of MES in Overall Equipment Effectiveness (OEE)
    MES enhances each OEE component by providing precise data capture, detailed analysis, and proactive intervention capabilities. Improving Availability. MES ...
  29. [29]
    Let's talk Manufacturing Execution Systems (MES) - The IT/OT Insider
    Sep 19, 2024 · ISA-95 is an international standard for integrating enterprise and control systems, organized into layers that range from physical processes to ...
  30. [30]
    Anomaly Detections for Manufacturing Systems Based on Sensor ...
    Dec 5, 2019 · In general, different anomaly detection techniques exist, which can be classified into statistical methods, such as Statistical Profiling ...
  31. [31]
    Anomaly Detection in Production Data: Finding the Signals in ...
    May 20, 2025 · Statistical anomaly detection methods work well in stable manufacturing environments with well-understood processes. These techniques establish ...
  32. [32]
    [PDF] Manufacturing Execution Systems
    In this model, the inputs into the production run (process, equipment, and material) are usually controlled to define a change in the batch ID (if any of the ...
  33. [33]
  34. [34]
    ISO 13485:2016 - Medical devices — Quality management systems
    In stock 2–5 day deliveryWhat is ISO 13485? ISO 13485 is the internationally recognized standard for quality management systems in the design and manufacture of medical devices.Missing: traceability | Show results with:traceability
  35. [35]
    What Is ISA-95? Manufacturing Data & a Single Ontology - Rhize
    ISA-95 defines a standard set of data models and object models for manufacturing operations, making it easier to exchange data between systems. Information ...
  36. [36]
    What is the Integration Between MES and ERP?
    May 2, 2024 · ISA-95 defines models and terminology to facilitate seamless communication and data exchange between Manufacturing Execution Systems (MES) ...Mes Erp Integration · Is Sap An Mes System? · Erp Vs Mes Vs Scada<|control11|><|separator|>
  37. [37]
    ERP and MES Integration: Methods, Benefits & Challenges - DCKAP
    Jan 16, 2025 · Improved Accuracy. Integration increases data accuracy by doing away with the need for manual data entry and lowering the risk of making ...
  38. [38]
    8 Ways MES ERP Integration Boosts Your Business | Frontier
    Mar 7, 2024 · MES ERP integration enables manufacturers to operate more efficiently, improve quality, and forecast more accurately for cost savings and business growth.
  39. [39]
    ERP-MES Integration using B2MML/XML schemas - IACS Engineering
    Here is a step-by-step tutorial that incorporates key expert considerations and practical refinements for an ERP-MES integration project using B2MML/XML schemas ...
  40. [40]
    ERP-MES Integration Using B2MML/XML to Control Systems
    Discover how to achieve seamless ERP-MES integration with B2MML/XML schemas aligned to ISA-95 standards. Learn protocols for SCADA/PLC connectivity via ...
  41. [41]
    MES vs ERP: Understanding Key Differences and Benefits for ...
    Nov 1, 2024 · This coordination supports accurate demand forecasting, improving inventory management, and cash flow planning.
  42. [42]
    The Future of Manufacturing Demands MES + ERP, Not One or the ...
    Apr 11, 2025 · Robust Financial & Supply Chain Management – Enables accurate forecasting, budgeting, and vendor coordination. Scalability for Growth – ERP ...
  43. [43]
    Integration of Production Orders with an MES - SAP Help Portal
    This business function enables you to better integrate your production orders with a manufacturing execution system (MES).
  44. [44]
    Overview Oracle MES for Discrete Manufacturing
    This chapter describes the features of the Oracle MES for Discrete Manufacturing, a manufacturing execution system used for discrete shop floor transactions.
  45. [45]
    ISA-95 Common Object Model - 4.2 ISA-95 Summary
    MES identify materials and their suitability for use, batch management systems confirm that the correct materials are used as specified in the recipes, ...<|control11|><|separator|>
  46. [46]
    Development of manufacturing execution systems in accordance ...
    This work presents how recent trends in Industry 4.0 (I4.0) solutions are influencing the development of manufacturing execution systems (MESs)
  47. [47]
    Assessing Industrial Communication Protocols to Bridge the Gap ...
    Jun 18, 2023 · In this work, we evaluate OPC-UA, Modbus, and Ethernet/IP with three machine tools to assess their performance and their complexity of use from a software ...Missing: MES | Show results with:MES
  48. [48]
    [PDF] A comprehensive study of industrial communication protocols and ...
    Jun 22, 2025 · Tapia et al. [6] conducted a performance evaluation for three communication protocols widely used in industry, MODBUS, OPC-UA Ethernet/IP. The ...
  49. [49]
  50. [50]
    ISA-95 Common Object Model - 4 Concept
    The 2010 versions of Parts 1 and 2 of the ISA-95 standard have been used to define a UA companion standard using OPC UA constructs for the purpose of exposing ...
  51. [51]
    [PDF] Why MES-LIMS integration is a game-changer - Infosys
    The integration of these systems offers a unified platform that bridges the gap between laboratory activities and manufacturing operations. This holistic ...
  52. [52]
    Laboratory Information Management Software Solutions
    Integrate your laboratory information management system (LIMS) with your manufacturing execution system (MES) to mitigate recalls, reputation damage and ...Laboratory Information... · Benefits Of Laboratory... · Accelerate Production With...
  53. [53]
    Connection of WMS and MES | Smart Factory | viastore SOFTWARE
    The integrative connection of warehouse management (WMS), transport control (WES) and production control system (MES) enables more transparency and efficiently ...
  54. [54]
    CMMS Integration with MES: Bridging the Gap Between ... - Shoplogix
    May 16, 2025 · Integrating CMMS with MES creates a unified data ecosystem that aligns maintenance activities with production schedules, reducing unplanned ...
  55. [55]
    (PDF) How the implementation of a manufacturing execution system ...
    This article seek to analyze and to describe the results obtained through the implementation of a Manufacturing Execution System (MES)Missing: uptime | Show results with:uptime
  56. [56]
    Smart Manufacturing - MESA International
    Benefits achieved with MES within Smart Manufacturing and the Digital Thread include: Automatic data collection; Repeatability; Control; Digitized records ...
  57. [57]
    AN IMPROVEMENT OF PRODUCTIVITY BY REAL TIME MACHINE ...
    Aug 7, 2025 · equipment productivity and efficiency (OEE) were increased by 10% to 15%, approximately. ... The improvement is around 15% compared due the ...
  58. [58]
    Boost Manufacturing Performance with OEE, MES & SCADA ...
    Actionable insights to drive continuous improvement; Increased OEE by 20% since the system implementation. Read Case Study. Make Better, Faster Decisions with ...
  59. [59]
    B2MML - Manufacturing Enterprise Solutions Association
    B2MML is an XML implementation of the ANSI/ISA-95, Enterprise-Control System Integration, family of standards (ISA-95), known internationally as IEC/ISO 62264.
  60. [60]
    How well is ISA-95 Adopted? - Jeff Winter
    May 27, 2025 · Released by the International Society of Automation around 2000,, it provides a common language and framework that links the “top floor” ( ...
  61. [61]
    (PDF) Reviewing Manufacturing Execution System in Industry 4.0
    Oct 29, 2025 · ... IoT, cloud computing, and cyber-physical systems. In the context of Industry 4.0, MES play a key role in enabling real-time decision-making ...
  62. [62]
    Systematic review of predictive maintenance practices in the ...
    A detailed review of predictive maintenance for the manufacturing industry. •. Analysis of machine learning and IoT for real-time fault detection and prediction ...
  63. [63]
    Digital Transformation: Integrating MES with AI Solutions - Retrocausal
    Jun 2, 2025 · A study by McKinsey & Company found that AI-powered predictive maintenance can reduce machine downtime by up to 50% and increase machine life by ...
  64. [64]
    Cloud-based manufacturing execution system: Case study FMS
    Aug 6, 2025 · This paper proposed a cloud based manufacturing execution system (CbMES) for covering existing gaps between manufacturing execution ...<|separator|>
  65. [65]
    How Edge Computing Enhances MES for Real-time Manufacturing ...
    Oct 24, 2024 · Discover how edge computing revolutionizes MES by enabling real-time data processing, reducing latency, and improving operational efficiency ...
  66. [66]
    Using MES/MOM to Improve Sustainability - ARC Advisory Group
    MES/MOM software can help companies monitor and optimize their production processes, identify areas of waste and inefficiency for improvement.Missing: features 2020
  67. [67]
    Digital Twin in MES: Transforming Manufacturing Execution Systems
    This blog post explores the impact of digital twins on MES and how they contribute to a smarter and more efficient manufacturing environment.
  68. [68]
    A Digital Twin-Based Distributed Manufacturing Execution System ...
    These emerging trends cover: cloud-based MES, IoT-based MES, intelligent MES, collaborative MES, supply chain linkage, MES mobility, and industrial data ...