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ASM

The American Society for Microbiology (ASM) is a professional scientific organization dedicated to advancing the study and application of microbiology, serving as the oldest and largest single life science membership organization globally with over 37,000 members from more than 100 countries as of 2025. Founded in 1899 as the Society of American Bacteriologists and renamed in 1960, ASM connects microbial scientists, educators, clinicians, and policymakers to foster discovery, education, and solutions to global challenges such as antimicrobial resistance, infectious diseases, and climate impacts on microbial ecosystems. ASM's mission emphasizes harnessing for the benefit of humanity through research dissemination, , and for and . The organization operates through a network of branches, student chapters, country ambassadors, and programs that build laboratory capacity in underserved regions and support outbreak responses. Its structure includes divisions focused on subfields like , , , and , enabling specialized collaboration among members. Key activities of ASM include leading scientific publishing with over a dozen peer-reviewed journals, such as the Journal of Bacteriology, Applied and Environmental , and mBio, which provide authoritative coverage of basic and clinical microbiology research. ASM also hosts major events like the annual ASM Microbe conference, the world's premier gathering for microbiologists, along with specialized meetings on topics like biofilms and . Additionally, through ASM Press, it produces essential resources like the Manual of Clinical Microbiology and educational materials to train the next generation of scientists. ASM's impact extends to advocacy, including efforts to strengthen microbial systems and promote equitable access to microbiological expertise worldwide. In February 2025, ASM removed (DEI) content from its website in response to a U.S. presidential . By supporting initiatives and interdisciplinary collaborations, ASM continues to drive innovations that address pressing societal needs, from pandemic preparedness to .

Codes

Country Codes

In the ISO 3166-1 standard, ASM serves as the three-letter alpha-3 code designating , an unincorporated territory of the located in the South Pacific Ocean. This code was established as part of the initial publication of in 1974, developed by the (ISO) in coordination with the to provide a uniform system for identifying countries and territories worldwide. The standard's alpha-3 format, using three uppercase letters, was designed to enhance clarity in alphanumeric compared to shorter alpha-2 codes, facilitating reliable without . The ASM code plays a critical role in various global systems, including data interchange protocols where it uniquely identifies American Samoa in electronic records, databases, and standardized formats such as XML or EDI for seamless across borders. In international trade, it is employed to denote origin or destination in customs declarations, tariff schedules under the , and shipping manifests, ensuring accurate tracking and compliance with trade regulations. Additionally, the code underpins the .as (ccTLD), delegated by the (IANA) to the AS Domain Registry for American Samoa since 1997, allowing entities to register that reflect territorial affiliation or creative uses like domain hacks. American Samoa's status as a U.S. territory dates to 1900, when the islands of and later the Manu'a Islands were ceded to the through treaties with local chiefs, with formal U.S. congressional occurring in 1929. This unincorporated and unorganized territory remains under U.S. sovereignty but is not part of any , granting it a distinct geopolitical position that necessitates precise identifiers like ASM for administrative purposes. The code streamlines logistical references in federal operations, such as postal services, , and economic reporting, by providing a concise, internationally recognized label that avoids confusion with independent nations or other U.S. possessions. Complementing the alpha-3 format, assigns the numeric code 016, a three-digit identifier derived from the ' statistical standards for numerical consistency in automated systems and legacy data formats. This numeric equivalent supports applications where alphabetic codes are impractical, such as in numerical sorting or integration with UN statistics, reinforcing ASM's utility in global datasets.

Airport Codes

Asmara International Airport, located in , the capital city of , is designated by the International Air Transport Association (IATA) with the code ASM. This code serves as the primary identifier for the facility in global airline scheduling and ticketing systems. The airport sits at an elevation of 7,661 feet (2,336 meters) above , which influences its operational conditions due to the high-altitude environment affecting aircraft performance. As 's largest and main , it functions as the country's primary gateway for passenger and cargo traffic, handling all scheduled international flights and supporting limited domestic services. The (ICAO) assigns the code HHAS to , which is utilized in aeronautical information publications, , and communications worldwide. This four-letter code facilitates precise coordination among pilots, controllers, and aviation authorities, ensuring safe navigation and routing in the region. Constructed by colonial authorities in as the first in , originally named Aeroporto di Asmara-Mai Temenai, the facility has undergone significant historical developments. During , it served as a key military airfield for Allied forces, including British and later U.S. operations, with proximity to the U.S. —a major communications base established in 1943 that enhanced regional signal intelligence until its closure in 1977. Following Eritrea's federation with in 1952 and in 1993, the airport retained its strategic role, particularly during the Eritrean-Ethiopian War (1998–2000), when it was targeted by Ethiopian airstrikes on June 5, 1998, underscoring its importance as a logistical and symbolic asset in the conflict. Today, it continues to operate as a vital hub despite periodic disruptions from regional tensions, including the suspension of flights since September 2024 due to a frozen bank account and unresolved financial disputes as of August 2025.

Organizations

Companies

ASM International N.V. is a multinational corporation headquartered in , specializing in the design, manufacture, and service of equipment for , with a focus on (ALD) and (CVD) technologies. Founded in 1968 by entrepreneur Arthur del Prado as Advanced Semiconductor Materials in Bilthoven, , the company emerged at the dawn of the to address early needs in epitaxial growth and wafer processing tools. In the , ASM expanded internationally, establishing ASM Japan in 1982 to support CVD product development and tapping into the growing Asian market for semiconductor equipment. In 2024, the company reported net sales with a 12% increase from 2023, driven by demand for advanced deposition solutions in logic and memory chip production. A key innovation from is the Eagle® XP8 platform, a high-productivity 300mm tool for plasma-enhanced ALD (PEALD) processes essential to advanced chip manufacturing. Launched to enable conformal deposition for applications like low-temperature spacers in and through-silicon via (TSV) isolation, the Eagle XP8 features up to four dual chamber modules for efficient high-volume , with independent chambers ensuring wafer-to-wafer uniformity and reduced cost of ownership through low-volume gas usage and quick access. This platform supports critical films used in scaling nodes, contributing to ASM's leadership in enabling next-generation logic and devices. ASM Technologies Limited is an engineering and IT services firm providing consulting, product , and solutions, with a emphasis on engineering services and research & (R&D) for global clients. Established in and publicly listed on the in 1994, the company operates offshore development centers in while maintaining a presence in the , , , , , and to deliver end-to-end product engineering and human-centric design services. ASM Technologies focuses on sectors including high-tech and engineering, partnering with international clients to provide outsourced product , support, and specialized solutions like cybersecurity through collaborations such as with Netherlands-based EclecticIQ.

Professional Societies

The (ASM), established in 1899, is a leading non-profit organization dedicated to advancing the microbial sciences through research, education, and advocacy, serving over 38,000 members worldwide including scientists, educators, and health professionals. It focuses on addressing global challenges such as , infectious diseases, and climate impacts on microbiomes, fostering collaboration across disciplines. ASM publishes influential open-access journals like mBio, which disseminates high-impact research on microbial biology and pathogenesis. The society hosts annual conferences, notably ASM Microbe, launched in 2016 as a premier event combining general meetings and specialized symposia to showcase cutting-edge microbial research and facilitate networking. ASM International, founded in 1913 as the American Society for Metals and renamed in 1986, is the world's largest association of materials-centric engineers and scientists, with over 12,000 professional members and 3,800 students, emphasizing education, knowledge sharing, and in and engineering. It provides s in areas such as , , and to enhance industry expertise and career advancement. Key publications include Metallurgical and Materials Transactions, a peer-reviewed covering physical , processing, and structure-property relationships in materials. The organization organizes events like the Materials Science & Technology (MS&T) conference series, which promotes innovation through technical presentations, exhibitions, and interdisciplinary discussions on applications. The American Society for Mass Spectrometry (ASMS), formed in 1969, is a non-profit dedicated to promoting the development and dissemination of knowledge in and allied topics, supporting researchers in fields ranging from to environmental analysis. It offers resources for professional growth, including workshops and advocacy for the technique's role in scientific discovery. ASMS publishes the Journal of the American Society for Mass Spectrometry (JASMS), a monthly peer-reviewed outlet for original research on instrumentation, methodologies, and applications of . The society's flagship event is its annual Conference on and Allied Topics, a major gathering featuring plenary lectures, workshops, and poster sessions to highlight advancements and foster collaborations among global experts.

Sports Clubs

ASM Clermont Auvergne, founded in 1911 and based in , , is a prominent club competing in the league. The club has secured two French championships ( Shield) in 2010 and 2017, along with three European Rugby Challenge Cup titles in 1999, 2007, and 2019. They play their home matches at the Stade Marcel-Michelin, a 19,022-capacity venue known as the "Yellow Army's" fortress. Notable players include prop Michael Alaalatoa and captain , who lead the squad's forward pack and leadership on the field. In the 2025–26 season, as of November 2025, ASM Clermont Auvergne holds a mid-table position, highlighted by a narrow 9-7 victory over on November 1. ASM Béziers Hérault, established in 1911 in , , is a historic club renowned for its golden era in the and , during which it captured 11 championships, the last in 1984. The club has also won four Challenge Yves du Manoir trophies and remains a cornerstone of local identity, fostering community pride through its heritage and youth development programs. Home games are hosted at the Stade Raoul Barrière, which holds approximately 13,500 spectators and serves as a hub for regional sporting events. Key figures include fly-half Samuel Marques, the team's leading scorer and try-maker in recent seasons, alongside emerging talents like hooker Yanis Lockwood. In the 2025–26 season, the second-tier league, ASM Béziers stands at 13th place with 15 points as of mid-November 2025, aiming for promotion through consistent performances.

Other Organizations

The Association of School and College Leaders (ASCL) is a UK-based and founded in 1977 as the Secondary Heads Association through the merger of the Association of Headmistresses and the Headmasters' Association. It supports school, , and trust leaders across primary, secondary, and post-16 by providing advocacy on key issues such as , workload, and , alongside tailored training programs to enhance skills. Post-2020, ASCL has actively influenced reforms, including campaigns for sustainable amid rising costs and staff shortages, as well as contributing to discussions on recovery from the disruptions through submissions to parliamentary committees and the publication of a 2025 roadmap for a resilient system emphasizing and collaboration. Membership benefits include access to expert legal and advice, discounted opportunities, and a network for peer support among over 25,000 leaders, with key initiatives such as the ASCL Trust Leaders Executive Programme offering certification-level training in and for aspiring and current CEOs of multi-academy trusts. The Aerospace Sciences Meeting (ASM), organized annually by the American Institute of Aeronautics and Astronautics (AIAA) since 1963, serves as a premier non-profit forum for advancing aerospace research through the presentation of technical papers on topics including , , and systems. This event fosters collaboration among scientists, engineers, and policymakers, featuring plenary sessions, workshops, and student competitions that highlight emerging technologies like hypersonics and sustainable aviation. The 2025 ASM, held as part of the AIAA SciTech Forum from January 6–10 in , adopted a format to accommodate both in-person attendance at the Hyatt Regency and participation, enabling broader global access with live-streamed sessions and on-demand content for over 5,000 combined attendees. Participation benefits include networking opportunities, access to proceedings via the AIAA , and awards recognizing high-impact contributions, such as the Dryden Lecture in Research. In scientific fields, professional societies like the AIAA host events such as the ASM to bridge research and application, distinct from ongoing membership organizations.

Military Applications

Air-to-Surface Missiles

Air-to-surface missiles (ASMs) are precision-guided munitions launched from , helicopters, or other aerial platforms to strike targets on land or the sea surface, setting them apart from air-to-air missiles designed for aerial intercepts. These weapons enhance strike capabilities by allowing attacks from standoff distances, minimizing exposure to ground-based defenses. Guidance systems vary but commonly include inertial navigation, satellite-aided GPS, electro-optical tracking, or designation to ensure accuracy against fixed or mobile targets. For instance, the U.S. employs semi-active homing in its E model, where a ground or airborne illuminator designates the target for the missile's seeker to home in on reflected energy, enabling effective engagement of armored vehicles and fortifications. The evolution of ASMs began during with unguided rockets, such as the U.S. (), a 5-inch deployed from fighter-bombers like the P-47 to suppress ground targets, though their unguided nature limited hit probabilities to around 5-10% under combat conditions. Early guided variants appeared late in the war, exemplified by the German , an air-launched with radio that was used against Allied shipping starting in 1943, achieving several hits but proving vulnerable to electronic countermeasures. Postwar developments in the era shifted toward autonomous guidance, with the U.S. deploying tactical ASMs like the in the 1950s, which used radio command for semiactive control against bunkers and bridges. Modern ASMs represent a leap in range, lethality, and survivability, incorporating features and advanced seekers. The UK's , developed in the 1990s by and entering RAF service in 2005, features dual-mode millimeter-wave radar and for operations against moving vehicles, with a blast-fragmentation tandem optimized for anti-armor penetration. In the U.S., the Joint Air-to-Surface Standoff Missile (JASSM), initiated in the late 1990s and operational by the mid-2000s, provides , low-observable cruise capability with GPS/inertial guidance and a 1,000-pound penetrating blast-fragmentation , with the standard variant having a of approximately 370 km and the extended-range variant (JASSM-ER) achieving up to 1,000 km to evade integrated air defenses. These systems prioritize integration, allowing real-time target updates via datalinks. Some ASMs also support anti-ship roles for engaging surface naval targets from airborne platforms. ASMs have seen extensive operational deployment, notably in the 1991 Gulf War, where the was fired over 5,000 times by U.S. A-10 Thunderbolt II and F-16 Fighting Falcon aircraft to neutralize Iraqi armor and artillery, contributing to the coalition's rapid campaign success with a reported hit rate exceeding 80% in clear weather. Contemporary platforms like the integrate ASMs such as JASSM for precision strikes, enabling internal carriage in configurations to maintain low observability while delivering warheads against high-value in contested environments. This integration supports multi-domain operations, with the F-35's providing terminal guidance cues to enhance missile effectiveness.

Anti-Ship Missiles

Anti-ship missiles (ASMs) are guided munitions specifically engineered to target and disable or sink naval vessels, including warships and merchant ships, by exploiting vulnerabilities in their hulls and superstructures. These weapons typically feature advanced guidance systems, such as active radar homing seekers, to achieve precision in maritime environments cluttered by waves and electronic interference. A prominent early example is the French-developed Exocet MM38, introduced in the 1970s, which uses a solid-propellant rocket motor and active radar for terminal guidance, with a range of approximately 40 kilometers from surface launch platforms. Later variants extended this capability, incorporating sea-skimming flight profiles to evade radar detection by hugging the ocean surface at altitudes as low as 1-2 meters. The evolution of ASMs has progressed from subsonic cruise missiles to advanced supersonic and hypersonic systems, enhancing speed, range, and survivability against modern defenses. The U.S. Harpoon missile, first deployed in 1977, marked a significant milestone as an all-weather, over-the-horizon weapon launchable from air, surface, and submarine platforms, with a turbojet engine enabling ranges up to 124 kilometers in its early variants. This design influenced global developments, emphasizing fire-and-forget autonomy and countermeasures like electronic jamming resistance. By the 2020s, hypersonic ASMs emerged, exemplified by Russia's 3M22 Zircon, a scramjet-powered missile capable of Mach 8-9 speeds and over 1,000-kilometer range, with initial naval deployments beginning in 2022 on frigates and submarines. The Zircon has been used in combat, with Russia deploying it against Ukrainian targets starting in 2024. Sea-skimming remains a core evasion technique across platforms, allowing missiles to exploit radar horizon limitations and reduce reaction time for interceptors. ASMs have seen combat deployment in key conflicts, demonstrating their tactical impact on naval operations. During the 1982 , Argentine forces launched missiles from Super Étendard aircraft, sinking the British destroyer HMS Sheffield and damaging HMS Glamorgan, which highlighted the vulnerability of unalerted fleets to low-flying attacks. In recent years, escalating tensions have intensified ASM proliferation, with China's 2020 test of an against a moving target underscoring threats to carrier strike groups, while U.S. integration of Long-Range Anti-Ship Missiles (LRASMs) on aircraft like the F/A-18, operational as of 2025, aims to counter regional naval expansions. These developments, including Japan's 2025 testing of the ground-launched , reflect a strategic focused on denying sea control in contested waters.

Computing and Technology

Assembly Language

is a that provides a symbolic representation of a computer's instructions, tailored to a specific . It employs human-readable mnemonics—such as MOV for moving data between registers or —to abstract opcodes, making it easier to write and understand code that directly controls . Programs written in are translated into by an assembler, a tool like NASM (), which uses syntax, or GAS (), which defaults to AT&T syntax. The development of began in 1947 with Kathleen Booth's creation of the first such language for the ARC (Automatic Relay Calculator) at Birkbeck College, , enabling symbolic programming over raw binary. This was followed by early implementations like the initial orders for the computer in 1949, which introduced subroutine libraries to simplify coding. Assembly languages have since evolved alongside processor architectures, resulting in dialects specific to instruction sets such as for general-purpose computing, for mobile and embedded devices, and for educational and networking applications. These dialects are essential in domains requiring fine-grained hardware control, including operating system kernels for processes and interrupt handling, embedded systems for optimizing performance in memory-limited environments, and for disassembling and analyzing compiled binaries. Central to programming are concepts like s and addressing modes, which facilitate efficient data manipulation and access. s, such as in the x86 , are small, high-speed storage locations within the CPU used for temporary data holding and arithmetic operations. Addressing modes specify how the CPU retrieves operands, including immediate (direct values), register (data in CPU registers), direct (specific memory locations), and indirect (via pointers). A simple example is the x86 instruction that loads an immediate value into a register:
assembly
MOV AX, 5   ; Loads the value 5 into the 16-bit AX [register](/page/Register)
This mnemonic-based assembles to the corresponding , illustrating how bridges human intent with machine execution.

Algorithmic State Machine

An Algorithmic State Machine (ASM) is a graphical representation technique for modeling finite machines (FSMs) in digital design, particularly for synthesis. ASM charts, the core of this method, use three primary elements: boxes to denote the current machine and associated unconditional outputs; decision boxes to evaluate conditional and determine transitions; and output boxes to specify conditional outputs based on decisions. This structure allows designers to describe the algorithmic behavior of hardware systems in a way that explicitly captures both and , facilitating the derivation of equations and logic implementations. The ASM methodology was introduced by Christopher R. Clare in his 1973 book Designing Logic Systems Using State Machines, where it was presented as a systematic approach to convert high-level algorithms into realizable digital circuits. Developed during the early era of integrated circuit design at Hewlett-Packard, ASMs gained prominence for their application in very-large-scale integration (VLSI) systems, enabling efficient synthesis of complex controllers. In modern practice, ASM charts serve as a behavioral specification that can be directly mapped to hardware description languages like VHDL or Verilog, allowing automated tools to generate gate-level netlists for FPGA or ASIC implementation. For instance, a traffic light controller ASM might include states for "red," "green," and "yellow," with transitions triggered by timer signals—such as advancing from green to yellow after a 30-second interval—while outputs drive the light indicators accordingly. In contrast to conventional flowcharts, which primarily depict sequential algorithms for software without inherent timing or state persistence, ASM charts are tailored for hardware FSMs and incorporate synchronous timing assumptions, ensuring that state changes occur only at clock edges. They align closely with the Moore model, where outputs depend solely on the current , or the Mealy model, where outputs also depend on inputs, providing a precise framework for avoiding race conditions in digital synthesis. The transition logic is formalized through state equations, such as \text{next_state} = f(\text{current_state}, \text{inputs}), which define how the machine evolves based on its present condition and external signals, enabling straightforward minimization and optimization during design. ASM charts may briefly inform low-level implementations in assembly language for microcontroller-based systems.

Attack Surface Management

Attack Surface Management (ASM) is a cybersecurity practice focused on the continuous discovery, analysis, prioritization, remediation, and monitoring of an organization's external digital attack surface to identify and mitigate potential vulnerabilities and exposures. This process encompasses all assets that could be exploited by adversaries, including internet-facing instances, application programming interfaces (), third-party services, and resources that may operate outside formal IT oversight. By maintaining visibility into these elements, ASM helps organizations address risks from both known and unknown assets in dynamic environments like hybrid infrastructures. ASM emerged as a distinct discipline in the early 2020s, driven by the increasing complexity of digital ecosystems and high-profile incidents, with early adopters leveraging specialized tools from providers such as for external exposure monitoring. Key processes in ASM include comprehensive asset inventory to catalog all external endpoints, automated vulnerability scanning to detect weaknesses, and risk prioritization using frameworks like the (CVSS), where, for instance, a score of 5.5 indicates medium severity requiring targeted remediation. These steps enable security teams to focus efforts on high-impact threats rather than exhaustive scans. The primary benefits of ASM lie in proactively reducing breach risks by shrinking the exploitable and enabling faster response to emerging threats, with organizations using ASM containing breaches 75% faster and achieving up to an 85% reduction in losses from external attacks, according to IBM's Cost of a Data Breach Report. In 2025, trends emphasize AI-driven automation for real-time and predictive risk scoring, alongside deeper integration with zero-trust architectures to enforce least-privilege access across discovered assets. A notable case illustrating ASM's necessity is the 2020 SolarWinds , where undetected third-party software vulnerabilities compromised over 18,000 organizations, underscoring the critical need for ongoing external asset discovery and exposure to prevent similar widespread incidents.

Transportation

Motorsports Teams

ASM Formule 3 is a motorsport team specializing in single-seater racing, particularly in Formula 3 categories. Founded in 1996 by , the team emerged from Vasseur's engineering background and initial successes in lower formulas like , establishing a reputation for developing young talent through structured driver programs and technical expertise. Based in , , ASM Formule 3 quickly rose to prominence by focusing on aerodynamic optimization, engine tuning, and data-driven strategies, often partnering with manufacturers like for power units in the mid-2000s. The team's early years included competitive outings in the French Formula 3 Championship, where it secured podiums and victories, laying the groundwork for international expansion. Entering the Formula 3 Euroseries in 2003, ASM Formule 3 achieved dominance, clinching four consecutive teams' championships from 2004 to 2007. In 2004, driver Jamie Green secured the drivers' title with multiple wins, including at key rounds like the , highlighting the team's Mercedes-powered chassis setup. The following year, 2005, dominated with 15 victories and 13 pole positions, earning the championship and showcasing ASM's ability to nurture Formula 1-bound talent through rigorous testing and simulation. followed in 2006, winning five races to claim the title, while capped the era in 2007 with six victories, four poles, and seven fastest laps, solidifying ASM's legacy in junior formulas. These successes were bolstered by technical partnerships, including engine supply from and chassis collaborations with , which emphasized reliability and performance in high-stakes European circuits. In the late 2000s, ASM Formule 3 transitioned under the broader banner—formed in 2005 by Vasseur and —allowing expansion into feeder series while maintaining its Formula 3 focus until 2007. Although direct participation fell to ART in the 2010s, where it won multiple titles (e.g., 2010 team championship), ASM's foundational infrastructure supported these efforts through shared facilities and engineering resources in . By the 2020s, the team evolved with the merger of GP3 and European F3 into the in 2019, continuing under ART with competitive lineups. In the 2025 FIA F3 season (concluded October 2025), fielded drivers James Wharton, Tuukka Taponen, and Laurens van Hoepen, finishing fourth in the teams' standings with 152 points, including podiums at rounds like Spa-Francorchamps and , demonstrating sustained adaptability to modern regulations. Concurrently, the organization shifted toward series, entering the by (FRECA) in the early 2020s to bridge junior categories, with drivers like achieving podiums in 2023, aligning with trends in sustainable racing through Alpine's hybrid-influenced platforms. This progression reflects ASM's enduring influence on motorsport pathways, prioritizing electric and hybrid technologies in emerging regional formulas while honoring its Formula 3 roots.

Arts and Media

Comics

The Amazing Spider-Man (often abbreviated as ASM) is a flagship Marvel Comics series centered on the superhero Spider-Man, created by writer Stan Lee and artist Steve Ditko. Launched in March 1963 with issue #1, it introduced Peter Parker's origin as a teenager bitten by a radioactive spider, granting him superhuman abilities and setting the stage for his dual life as a student and vigilante. The series quickly established Spider-Man as a relatable everyman hero, grappling with personal responsibilities alongside extraordinary powers, and has since become one of Marvel's longest-running titles. Publication history spans multiple volumes, with the original run from 1963 to 1998 comprising 441 issues, followed by relaunches and continuations that reached legacy issue #700 by 2013 and exceeded 900 issues by 2025 across all volumes, including a relaunch as Volume 7 in June 2025 that began at legacy #965 and reached #980 with issue #16 on November 18, 2025. After Ditko's departure in 1966, artist took over penciling duties starting with issue #38, defining a pivotal era through issue #119 with his dynamic, expressive style that emphasized Spider-Man's agility and emotional depth. The series has featured evolving creative teams, incorporating social themes like drug addiction in the and identity crises in later decades, while maintaining core elements of high-stakes action and moral dilemmas. Key story arcs include "" in #121 (June 1973), written by and penciled by , where fails to save his girlfriend from the , marking a turning point in by killing off a major love interest and exploring irreversible loss. This narrative shattered the era's conventions of invulnerable heroes and their relationships, influencing character development across titles. The series has also included numerous crossovers, such as team-ups with the Avengers in events like "" (2011), where collaborates with Earth's Mightiest Heroes against a citywide villainous plot. Adaptations of ASM into other media highlight its versatility, notably the 2012 film , directed by and starring as Peter Parker, which rebooted the franchise with a darker, mystery-driven origin emphasizing Parker's scientific curiosity and family secrets. This production grossed over $758 million worldwide and spawned a , bridging comic lore with modern cinematic spectacle. The series' cultural impact extends to pop culture, transforming into a symbol of youthful resilience and ethical responsibility, as analyzed in scholarly works on how and the character redefined the modern American hero amid 1960s social changes. In terms of commercial success, ASM has set sales benchmarks, with issue #698 (November 2012)—part of the "" arc leading to the storyline—selling 81,342 copies to North American comic shops.

In live theater production, the assistant stage manager (ASM) serves as a vital crew member, supporting the stage manager by prompting , overseeing prop management, and ensuring seamless backstage coordination during both rehearsals and performances. This role acts as the stage manager's primary deputy, handling on-stage and off-stage logistics to maintain the production's flow without disrupting the audience's experience. ASMs are essential in professional settings, where they bridge the gap between creative direction and technical execution, often stepping in to resolve immediate issues like forgotten lines or equipment malfunctions. Key duties of an ASM include annotating the script with detailed notes on blocking, cues, and effects; calling cues to members during performances; and conducting oversight to prevent accidents in high-pressure environments. They also track and preset props, organize rehearsal schedules, and communicate updates to the cast and team, ensuring all elements align with the director's vision. Training for ASMs typically occurs through apprenticeships and certification programs affiliated with organizations like the Actors' Equity Association (AEA), which has represented stage managers since its founding in to protect their professional standards and working conditions. The AEA's Equity Membership Candidate (EMC) program allows aspiring ASMs to gain credited experience in union theaters, building skills in a structured, mentorship-based environment. The ASM role has evolved significantly from its origins in 19th-century theater, where prompters—often positioned in a prompt corner—primarily fed lines to and managed basic cues amid emerging stage technologies like and mechanized scenery. By the mid-20th century, particularly after , the position formalized into a dedicated assistant role within a team structure, expanding responsibilities to include comprehensive production oversight as shows grew more complex. In contemporary practice as of 2025, ASMs integrate advanced technologies such as communication headsets and prompt books, enabling coordination across venues and reducing physical cabling for greater and efficiency.

Other Uses

Business Roles

In business contexts, the abbreviation ASM commonly refers to several supervisory and operational roles across , , and sectors. These positions typically involve leadership, monitoring, and support functions to drive organizational efficiency and growth. The Assistant Store Manager (ASM) is a key supervisory responsible for overseeing daily operations, including scheduling, , and , as well as managing levels and ensuring compliance with safety standards. In the absence of the manager, the ASM assumes full operational leadership, directing personnel to meet targets and maintain . This has been prevalent in large chains since the 1990s, exemplified by , where ASMs supervise teams, handle merchandising, and contribute to profitability through hands-on involvement in tasks like and freight management. The Area Sales Manager (ASM) focuses on regional sales oversight, leading teams of representatives to achieve territory-specific goals through development, client relationship building, and analysis. Responsibilities include setting targets, coaching staff on techniques, and monitoring competitive landscapes to expand . Key performance indicators (KPIs) for ASMs often emphasize quarterly growth, such as targets aligned with overall expansion rates, alongside metrics like team quota attainment and . Application Support and Maintenance (ASM) denotes an IT role centered on the ongoing upkeep of software applications, including user issues, applying updates, and ensuring system reliability to minimize . ASMs handle incident , optimization, and preventive maintenance, often collaborating with development teams for enhancements. agreements (SLAs) are integral, specifying response times such as a 4-hour fix for critical issues to maintain operational continuity.

Science and Medicine

Airway (ASM) refers to the contractile that lines the walls of the respiratory tracts, enabling airway narrowing and relaxation to regulate . In the of , ASM plays a central role by mediating acute and contributing to airway hyperresponsiveness, where airways overreact to stimuli such as allergens or irritants, leading to exaggerated narrowing. Early investigations in the , including studies on calcium-dependent mechanisms, linked ASM's excitation-contraction coupling to asthmatic , highlighting its involvement in stimulus-secretion coupling and mediator release from inflammatory cells. Although initial experiments on excised ASM often failed to strongly implicate it in hyperresponsiveness, subsequent established ASM's hypercontractile and remodeling as key drivers of symptoms. Beyond , ASM proliferation and dysfunction are prominent in (COPD), where increased ASM mass leads to airway remodeling, persistent narrowing, and reduced lung function. In COPD, ASM cells exhibit altered contractility due to and inflammatory signals, exacerbating airflow limitation. Treatments targeting ASM, such as β2-agonists, promote bronchodilation by activating receptors on ASM cells, which inhibit - cross-bridge formation and reduce contractile force. At the cellular level, - interactions in ASM are regulated by associated proteins like cortactin, which controls actin polymerization and force generation without directly affecting light chain , offering insights into therapeutic modulation of ASM tone in respiratory diseases. In scientific and medical contexts, ASM also denotes Annual Scientific Meeting, a standard format for professional conferences that facilitate knowledge exchange in specialized fields such as . For example, the Singapore Society of Oncology held its 10th Annual Scientific Meeting on 3–4 October 2025 at the Grand Copthorne Waterfront in , emphasizing clinical advancements and research collaboration.

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