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Active packaging

Active packaging is a form of food packaging that incorporates deliberate interactions between the packaging material, the packaged product, and the surrounding environment to extend shelf life, enhance food safety, or improve sensory attributes by releasing or absorbing specific substances such as gases, moisture, antimicrobials, or antioxidants.^[1] Unlike traditional passive packaging, which serves primarily as a barrier, active packaging employs subsidiary constituents integrated into or on the packaging to actively modify internal conditions, such as reducing oxygen levels or emitting carbon dioxide, thereby mitigating spoilage mechanisms like oxidation and microbial growth.^[2] The concept has roots in ancient preservation techniques but saw modern development in the 1970s, with significant research acceleration over the past two decades, including over 4,400 publications between 2019 and 2024 focused on innovative applications.^[1] Key types include scavenging systems, which absorb unwanted elements like oxygen (e.g., via iron-based reactions or enzymatic processes), ethylene (to delay fruit ripening), or moisture; releasing systems, which deliberately emit compounds such as antimicrobials (e.g., essential oils like thymol), antioxidants (e.g., phenolic extracts from natural sources), or flavors; and controlled release packaging, which ensures gradual diffusion of active agents influenced by factors like temperature, pH, and humidity.^[2] These mechanisms are regulated under frameworks like EU Regulation 1935/2004, which permits such interactions provided they do not endanger health or alter food composition undesirably.^[3] Applications span perishable foods, including meats (e.g., pork patties preserved against lipid oxidation), dairy products (e.g., cheese protected from mold), fruits and vegetables (e.g., strawberries with reduced ethylene-induced decay), and even beverages or baked goods, where active systems can extend shelf life up to fivefold compared to conventional methods.^[1] Benefits include reduced food waste, minimized use of synthetic preservatives, and alignment with sustainability goals through bio-based materials like chitosan or polylactic acid (PLA), which support biodegradability.^[2] Recent trends from 2019–2024 emphasize natural extracts (e.g., essential oils and phenolic compounds from agricultural by-products) and nanoencapsulation for controlled efficacy, alongside pilot-scale implementations and patents advancing commercialization.^[1]

Fundamentals

Definition and Principles

Active packaging refers to packaging systems that incorporate materials or substances designed to interact dynamically with the internal package environment or the packaged product, thereby extending shelf life, enhancing safety, and maintaining quality by modifying factors such as gas composition, microbial growth, or oxidation.^[4] Unlike traditional passive packaging, which acts merely as a barrier, active packaging employs deliberate interventions to absorb, release, or neutralize specific compounds, often through integrated additives like sachets, films, or coatings.^[3] This approach is particularly applied in food preservation but extends to pharmaceuticals and other perishables, where it targets deterioration mechanisms like lipid oxidation or enzymatic browning.^[5] The core principles of active packaging revolve around two primary functions: scavenging and releasing. Scavenging involves the removal of undesirable substances, such as oxygen or ethylene, to prevent spoilage and maintain an optimal atmosphere within the package.^[6] Releasing principles entail the controlled addition of beneficial agents, including antimicrobials, antioxidants, or flavor compounds, to inhibit microbial proliferation or compensate for quality loss during storage.^[3] These principles operate synergistically to create a tailored microenvironment that extends product viability without altering the food itself directly. Active packaging is distinct from intelligent packaging, which primarily focuses on monitoring and communicating the product's condition through indicators like time-temperature integrators or freshness sensors, without actively intervening in the preservation process.^[7] In contrast, active systems emphasize direct chemical or physical interactions—such as gas absorption or substance emission—to alter the package headspace or product interface for preservation, rather than passive observation.^[3] This delineation ensures active packaging prioritizes intervention over mere detection, though hybrid systems combining both are emerging in advanced applications. At the mechanistic level, active packaging relies on processes like diffusion-controlled release, where active agents migrate from the packaging material to the product surface at rates governed by concentration gradients and material permeability, enabling sustained delivery of preservatives.^[8] Adsorption mechanisms facilitate scavenging by binding target molecules, such as oxygen, onto reactive sites within the packaging matrix, often using materials like iron-based powders or zeolites.^[4] Enzymatic reactions provide another key pathway, particularly in bio-based systems, where immobilized enzymes catalyze the breakdown of spoilage precursors, such as converting hydrogen peroxide to water and oxygen in antimicrobial applications.^[9] These mechanisms ensure efficient, targeted interactions while minimizing unintended migration or waste.

History and Development

The concept of active packaging originated in the late 1970s, driven by the need for enhanced food preservation amid growing global trade in perishable goods. In Japan, Mitsubishi Gas Chemical Company pioneered the commercial use of iron-based oxygen absorbers with the introduction of the "Ageless" sachet in 1977, initially applied to rice packaging to prevent oxidation and mold growth.^[10] This innovation marked the first widespread adoption of active components in packaging, building on earlier research into oxygen-scavenging materials patented in 1978.^[11] By the early 1980s, the technology expanded to include ethylene scavengers, such as potassium permanganate-based systems commercialized in Japan for extending the shelf life of fruits and vegetables by absorbing the ripening hormone ethylene.^[12] The 1990s saw significant growth in active packaging applications, particularly with the integration of modified atmosphere packaging (MAP) for meat products, which combined gas control systems to inhibit microbial growth and maintain color. Retail adoption surged, with UK MAP sales for meats and other products rising from about 2 billion packages in the mid-1990s to 2.8 billion by 1998, reflecting improved supply chain logistics and consumer demand for fresher foods.^[13] Entering the 2000s, the field advanced with the incorporation of antimicrobial agents into packaging films, such as nisin-releasing systems for dairy and meats, enhancing safety against pathogens like Listeria.^[14] This period also benefited from regulatory support, notably the European Union's Regulation (EC) No 1935/2004, which established safety standards for active materials in contact with food, facilitating broader commercialization across Europe.^[15] By the 2010s, active packaging extended beyond food into pharmaceuticals and cosmetics, with developments like hot-melt extruded films for controlled release of preservatives in topical drug products to improve stability and shelf life.^[16] This diversification was spurred by sustainability pressures and advancements in material science. The global market for active packaging, valued at approximately $19.7 billion in 2020, reflected this momentum and reached about $33 billion by 2025.^[17]^[18]

Gas and Atmosphere Control

Oxygen Scavenging

Oxygen scavenging is a key active packaging technology designed to remove residual oxygen from the package headspace and dissolved oxygen in food products, thereby preventing oxidative rancidity, microbial growth, and spoilage. This process is particularly vital for oxygen-sensitive foods, where even low levels of oxygen (typically 1-2% in modified atmosphere packaging) can accelerate deterioration. Common formats include sachets placed inside the package or oxygen-absorbing films and labels integrated directly into the packaging material.^[19] The primary mechanisms of oxygen scavenging involve metallic, chemical, and enzymatic reactions. Metallic scavengers, such as iron powder-based systems, rely on the oxidation of ferrous iron to ferric oxide in the presence of moisture, consuming oxygen stoichiometrically (up to 0.5 g of oxygen per gram of iron). These are widely used due to their high capacity and cost-effectiveness, with commercial examples like Ageless sachets (Mitsubishi Gas Chemical, Japan) capable of absorbing 20-300 cm³ of oxygen per sachet. Chemical scavengers include sulfite-based systems, where sodium metabisulfite reacts with oxygen to form sulfate, and ascorbic acid systems, which oxidize to dehydroascorbic acid, often catalyzed by transition metals like copper. Enzymatic scavengers employ glucose oxidase, which catalyzes the oxidation of glucose to gluconic acid and hydrogen peroxide in the presence of oxygen, with catalase subsequently decomposing the peroxide to water and oxygen, enabling a net removal of half a mole of oxygen per mole of glucose consumed.^[20]^[19]^[21] Applications of oxygen scavengers are prominent in the food industry, especially for snacks such as nuts, cookies, and dried meats, where they inhibit lipid oxidation and maintain crispness, and in beverages like beer and fruit juices packaged in PET bottles, where they prevent flavor staling and vitamin C degradation. For instance, ascorbic acid-integrated crown caps or labels in beverage bottles effectively target headspace oxygen. These systems are often combined with modified atmosphere packaging to achieve comprehensive gas control.^[20]^[21]^[20] In terms of effectiveness, oxygen scavengers can reduce headspace oxygen levels to below 0.5% (often <0.01%) within 12-48 hours at ambient temperatures, depending on the system and package size; iron-based sachets, for example, achieve this in 5-6 days for 300 cm³ volumes. Ascorbic acid systems in beverage packaging have demonstrated retention of up to 90% of initial vitamin C over extended storage. Overall, these technologies extend shelf life by 50-100% in products like cheese, meat, and snacks by minimizing oxidative changes and microbial proliferation.^[20]^[21]^[20] Advantages of oxygen scavenging include targeted oxygen removal without direct food additives, enhanced product quality, and versatility across dry and moist foods, leading to reduced food waste. However, limitations exist, such as the need for activation by trace moisture and oxygen (particularly for iron-based systems, which may not function optimally in fully anaerobic conditions initially), potential off-odors from incomplete reactions (e.g., metallic tastes from iron oxidation), and sensitivity to environmental factors like pH and temperature, which can reduce efficacy in enzymatic systems. Regulatory approval ensures safety, but integration into packaging must avoid migration of byproducts into food.^[19]^[20]^[21]

Ethylene Scavenging

Ethylene scavenging in active packaging involves the targeted removal or decomposition of ethylene gas, a plant hormone that accelerates ripening and senescence in climacteric fruits and vegetables, thereby extending post-harvest shelf life.^[22] This process is essential for maintaining produce quality during storage and transportation, as ethylene levels as low as parts per billion can trigger rapid deterioration. Common mechanisms include chemical oxidation, physical adsorption, and photocatalytic degradation, often integrated into packaging materials like films, pouches, or sachets.^[23] One primary mechanism utilizes potassium permanganate (KMnO₄)-based absorbers, where the compound oxidizes ethylene to carbon dioxide, water, acetaldehyde, and acetic acid, indicated by a color change from purple to brown upon saturation.^[22] Another approach employs zeolite or clay materials, such as halloysite nanotubes or bentonite, which physically adsorb ethylene through their porous structures, sometimes enhanced by impregnation with metal cations like copper or zinc for improved selectivity.^[24] Photocatalytic decomposition using titanium dioxide (TiO₂) represents a third method, where TiO₂, activated by ultraviolet light, breaks down ethylene into harmless byproducts like CO₂ and water, often incorporated into polymer films for continuous activity.^[22] These systems find widespread applications in packaging for ethylene-sensitive produce, including apples and bananas, where sachets or embedded films capture trace ethylene levels to delay ripening.^[25] For instance, KMnO₄-impregnated pouches are placed in crates or shipping containers to protect bananas during transit, while TiO₂-coated films line apple storage bags to minimize gas accumulation.^[22] Effectiveness varies by mechanism and produce type, but KMnO₄ absorbers can reduce ethylene concentrations by up to 90% in controlled atmospheres, extending banana shelf life from about 12 days to 20 days at ambient conditions.^[26] Similarly, zeolite-modified films have prolonged mango storage to 40 days by adsorbing 50-70% of ethylene, and TiO₂ systems in tomato packaging achieve up to 80% reduction, adding 14 days to shelf life.^[22] Commercial examples include KMnO₄-based sachets like those from Keep It Fresh, used in shipping containers for global produce transport, and zeolite-infused products such as Freshness Plus Bags for retail apple packaging.^[27]^[22] Challenges in ethylene scavenging include achieving high selectivity to avoid interaction with other gases like CO₂ or water vapor, which can reduce efficiency in humid environments.^[28] Additionally, many systems, particularly KMnO₄ and TiO₂-based ones, are non-regenerable and require replacement once saturated, though research into reusable zeolite frameworks via thermal or chemical recharging shows promise for sustainable applications.^[22]

Modified Atmosphere Systems

Modified atmosphere systems in active packaging actively regulate the gaseous composition within a package to extend shelf life and maintain product quality by emitting or absorbing specific gases, primarily carbon dioxide (CO₂), often in combination with oxygen scavengers to achieve balanced modified atmosphere packaging (MAP). These systems counteract natural respiration or microbial activity that alters the internal atmosphere, optimizing conditions for perishable foods. CO₂ emitters typically rely on chemical reactions, such as the interaction of sodium bicarbonate (NaHCO₃) with citric acid in the presence of moisture from the food product, generating CO₂ to elevate headspace levels and inhibit spoilage. Conversely, CO₂ absorbers employ mechanisms like the reaction of calcium hydroxide (Ca(OH)₂, or lime-based compounds) with excess CO₂ to form calcium carbonate (CaCO₃) and water, preventing package bulging or acidification in CO₂-producing foods. These components are frequently integrated with oxygen scavengers to maintain low oxygen levels (typically <1-2%) alongside targeted CO₂ concentrations, ensuring a stable environment that suppresses oxidative and microbial degradation.^[29]^[30] Applications of modified atmosphere systems span meats, dairy products, and baked goods, where they preserve freshness by establishing specific gas ratios, such as 20-40% CO₂ balanced with nitrogen (N₂) and minimal oxygen. In red meats and poultry, elevated CO₂ levels (e.g., 20-30%) dissolve into the product to form carbonic acid, lowering pH and retarding the growth of aerobic bacteria like Pseudomonas spp. Dairy items, including cheese and yogurt, benefit from 30-40% CO₂ to control mold and yeast proliferation without excessive acidification. For baked goods like bread or pastries, systems maintain 20-25% CO₂ to mitigate staling and microbial spoilage during distribution. These applications are particularly effective in refrigerated chains, where the systems dynamically adjust to gas fluctuations from product respiration or environmental exposure.^[30]^[31] The effectiveness of these systems lies in their ability to inhibit aerobic bacterial growth and extend shelf life, with case studies demonstrating 2-3 times longer preservation for poultry products under refrigeration. For instance, MAP with 20-40% CO₂ in chicken packaging reduces total viable counts and delays spoilage odors, achieving up to 150% shelf life extension compared to air packaging, from 7-10 days to 14-21 days at 4°C. Similar benefits apply to dairy and baked goods, where CO₂ modulation minimizes lipid oxidation and texture degradation. Types include sachet-based systems, where absorbers or emitters are enclosed in permeable packets placed inside the package for easy integration, versus label-integrated formats that embed reactive materials directly into adhesive labels for compact, tamper-evident designs. Recent evolutions incorporate smart films responsive to pH changes, which trigger CO₂ release or absorption based on spoilage indicators like lactic acid buildup, enhancing precision in dynamic environments.^[31]^[32]

Moisture and Corrosion Management

Moisture Regulation

Active packaging systems for moisture regulation employ materials that dynamically interact with the internal package environment to absorb excess water vapor or release moisture as needed, thereby maintaining optimal relative humidity (RH) levels and preventing product degradation such as mold growth, clumping, or desiccation. These systems are particularly vital for sensitive foods where uncontrolled humidity can compromise quality, with desiccants serving as the primary absorption mechanism by adsorbing water molecules onto their porous surfaces. Common desiccants include silica gel, which can absorb up to 35% of its weight in water while remaining chemically inert, and natural clays like bentonite or montmorillonite, which are cost-effective for large-scale use and often packaged in sachets or integrated into films.^[33]^[34] For scenarios requiring moisture release, humidifying agents such as glycerol or saturated salt solutions (e.g., magnesium chloride) are incorporated, which gradually emit water vapor to counteract overly dry conditions and preserve product texture.^[35] Applications of moisture regulation in food packaging include hygroscopic products such as cereals, dried fruits, and snacks, where moisture absorbers mitigate clumping and staleness, while humidifiers protect moisture-sensitive items like baked goods from drying out, thereby extending shelf life without altering sensory attributes.^[33] These applications collectively prevent issues like condensation in cold-chain transport or excessive drying in arid climates. The effectiveness of these systems typically sustains RH between 20% and 60%, a range optimal for most moisture-sensitive foods, with absorption capacities varying by desiccant type—silica gel maintaining below 10% RH for ultra-dry needs and clay desiccants achieving 20-40% RH in moderate conditions.^[36] A representative example is two-way humidity control in herb packaging, where reversible sorbents like Boveda packs stabilize RH at around 62% to preserve aroma and prevent brittleness or mold.^[37] Innovations in this area include reversible desiccants, such as cellulose fiber pads impregnated with salts, which adapt to fluctuating environmental conditions by alternately absorbing and releasing moisture without reaching saturation, enabling longer-term regulation in dynamic supply chains.^[33] These advancements, often integrated into biodegradable films or smart labels, enhance sustainability while providing precise control, as demonstrated in recent reviews of active packaging technologies.^[38]

Corrosion Prevention

Active packaging incorporates corrosion prevention strategies to safeguard metal components from oxidative degradation, particularly in environments where moisture acts as a primary trigger for rust formation. Volatile corrosion inhibitors (VCIs) are key agents in this approach, releasing protective vapors within sealed packaging to form molecular barriers on metal surfaces, thereby interrupting electrochemical reactions that lead to corrosion.^[39] These inhibitors are especially vital for maintaining the integrity of packaging materials during storage, transport, and use in humid conditions.^[40] The primary mechanism of VCIs involves the volatilization of organic compounds, such as amine benzoates or sodium benzoates, which evaporate at ambient temperatures and condense on metal substrates to create a thin, adsorbed protective film. This film acts as a passivation layer, reducing the interaction between the metal and corrosive agents like oxygen and water vapor by altering the surface pH or forming insoluble complexes. For instance, amine-based VCIs neutralize acidic corrosion products, while benzoates provide anodic inhibition through adsorption.^[41] VCIs operate predominantly in the vapor phase, allowing uniform coverage even on hard-to-reach areas, though contact-phase variants rely on direct physical application for immediate surface protection.^[42] These inhibitors are integrated into packaging formats like polyethylene films, kraft papers, or emitters, enabling controlled release over extended periods without residue upon unpacking.^[43] In applications, VCIs are widely employed in metal cans for food and beverages to prevent internal rusting that could contaminate contents, using FDA-compliant formulations that ensure safety during processing and storage.^[44] Effectiveness is demonstrated through standardized testing, where VCIs significantly lower corrosion rates compared to unprotected controls.^[43]

Metal Chelation

Metal chelation in active packaging involves the use of chelating agents that bind free metal ions, such as iron (Fe³⁺) and copper (Cu²⁺), to form stable complexes, thereby preventing these ions from catalyzing oxidative reactions in packaged foods. Common synthetic chelators include ethylenediaminetetraacetic acid (EDTA), which forms strong, non-redox-active complexes with transition metals, while natural alternatives like citric acid provide milder chelation through carboxylate groups.^[45] These agents can be incorporated directly as food additives or immobilized onto packaging films via techniques such as photografting iminodiacetic acid (IDA) onto polypropylene substrates, ensuring non-migratory activity to avoid direct addition to the product. In applications, metal chelators are particularly effective in beverages and sauces, where trace metals leached from packaging or processing equipment can accelerate oxidation, leading to discoloration and off-flavors. For instance, IDA-functionalized films have been shown to protect ascorbic acid in acidic beverages (pH 3.0) by extending its half-life from 5 days in controls to 14 days, comparable to EDTA's performance. In emulsified sauces, similar chelating coatings inhibit lipid oxidation by prolonging the lag phase from 5 days to 25 days, preserving sensory quality without altering the food matrix. This targeted approach addresses ionic metals within the product, distinct from surface-level corrosion control on packaging materials. The effectiveness of these systems stems from their high binding affinities; for example, IDA ligands exhibit stability constants of 10.72 for Fe³⁺ and 10.57 for Cu²⁺, enabling chelation capacities of up to 138 nmol/cm² for iron. Performance is pH-dependent, with chelating efficiency increasing as pH rises due to deprotonation of ligand groups like carboxylates. Overall, these mechanisms specifically target trace-level pro-oxidant metals (often <1 ppm), mitigating Fenton-type reactions that generate hydroxyl radicals and degrade nutrients.^[45]

Temperature Management

Temperature Monitoring

Temperature monitoring in active packaging primarily relies on time-temperature indicators (TTIs), which are sensors designed to detect and signal deviations from optimal temperature conditions, thereby ensuring the integrity of temperature-sensitive products. These indicators provide visual or digital alerts about exposure to adverse temperatures, helping to track cumulative thermal history without requiring external power in many cases. TTIs are integral to maintaining product quality by alerting handlers to potential spoilage risks during storage and transport.^[46] Key mechanisms include enzymatic color-change labels, where enzymes such as lipases react with substrates and pH-sensitive dyes to produce irreversible color shifts, for instance, from green to orange-red in the CheckPoint® system, indicating cumulative exposure. Another approach involves laccase enzymes immobilized on electrospun fibers that catalyze oxidation reactions, leading to a color change from transparent to purplish brown when milk is exposed to temperatures above 4°C, correlating with lactic acid bacterial growth. For ultra-cold applications, diffusion-based TTIs use dyed noneutectic mixtures, such as ethylene glycol/water, that migrate into an absorbent material upon temperature rises, triggering a visible color change above thresholds like -60°C. RFID-embedded sensors integrate temperature detection with wireless data transmission, enabling real-time monitoring of conditions like those for frozen fish.^[46]^[47]^[48]^[46] TTIs are categorized into threshold types, which activate upon exceeding a specific temperature (e.g., the Monitor Mark indicator for frozen or chilled foods), and integrated exposure monitors that accumulate data over time via color progression to reflect total thermal abuse. Data-logging variants, often RFID-based, record detailed histories for compliance verification. In applications, these are widely used in cold-chain logistics for perishables such as meat, dairy, and fruit, where they track exposure during distribution to prevent spoilage, and for vaccines, ensuring ultracold integrity (e.g., -70°C storage) by detecting excursions lasting over 2-5 minutes.^[46]^[49]^[46]^[48] Effectiveness is demonstrated by high predictive accuracy; for example, enzyme-based TTIs for dairy achieve prediction errors below 10% across 10-37°C, with activation energies aligning closely (within ±25 kJ/mol) to microbial growth kinetics. In meat supply chains, integrated TTIs like OnVu™ show R² values exceeding 0.95 and accuracy factors near 1.01, enabling shelf-life predictions within 24 hours of microbial assessments. These indicators thus support proactive quality management, though challenges like minor inaccuracies in variable conditions persist.^[47]^[50]^[50]

Active Temperature Control

Active temperature control in packaging involves embedded systems that dynamically maintain or adjust internal temperatures to protect sensitive contents from environmental fluctuations during storage and transport. These systems go beyond passive insulation by incorporating materials or devices that actively absorb, release, or generate heat, ensuring product integrity for perishable goods. Common mechanisms include phase-change materials (PCMs), thermoelectric elements like Peltier devices, and chemical reaction-based heaters, each tailored to specific temperature ranges and durations. Phase-change materials represent a primary mechanism for temperature stabilization, operating through reversible phase transitions that absorb or release latent heat at predetermined temperatures without external power. In pharmaceutical applications, PCMs such as paraffin-based formulations with melting points around 4.5°C to 8°C are integrated into pouches or panels within insulated boxes to maintain the critical 2-8°C range required for biologics and vaccines, preventing denaturation during transit. For frozen foods, salt hydrate PCMs operating at -20°C to -18°C help sustain sub-zero conditions, with examples including gel packs in multi-layer containers that extend holding times up to 72 hours under ambient temperatures of 20-30°C. Effectiveness is demonstrated by their ability to dampen fluctuations by 5-10°C; for instance, paraffin PCMs have been shown to keep meat products at an average 12.5°C for 133-137 minutes longer than non-PCM systems, reducing spoilage rates.^[51]^[52]^[53] Active electronic systems, such as Peltier elements, provide powered cooling or heating via the thermoelectric Peltier effect, where an electric current drives heat transfer across semiconductor junctions. These are particularly useful for short-term interventions in refrigerated transport of pharmaceuticals and perishables, integrated into packaging walls to counteract door openings or delays, maintaining stability within 2°C of set points. In tests with fruit shipments, battery-powered Peltier modules reduced average product temperatures from 3.2°C to 2.8°C—a 12.5% improvement—while minimizing energy use through intermittent operation (e.g., 7.5 minutes on, 2.5 minutes off). For heating needs, exothermic chemical reactions offer a non-electric alternative, such as quicklime (CaO) reacting with water to generate heat up to 40-60°C in self-heating cans for ready-to-eat meals, providing rapid activation (within 3 minutes) without batteries. These systems are powered by rechargeable lithium batteries for Peltier setups or self-contained reagents for chemical methods, enabling portable, short-term control of 4-48 hours depending on payload.^[54]^[54]^[55] Overall, active temperature control enhances supply chain reliability, with PCM pouches in insulated shippers exemplifying versatile deployment for both cooling and mild heating scenarios in biologics transport. While these interventions can be verified using integrated monitoring tools, the focus remains on proactive thermal management to minimize excursions.

Antimicrobial and Preservation Features

Antimicrobial Systems

Antimicrobial systems in active packaging incorporate agents that directly inhibit or kill microorganisms within the package, extending the shelf life of perishable foods by targeting bacterial, fungal, and yeast growth. These systems typically involve the integration of antimicrobial compounds into packaging materials, such as polymers or films, where they interact with the food surface or the headspace to prevent spoilage. Common agents include inorganic nanoparticles, organic acids, and bioactive peptides, selected for their broad-spectrum efficacy and compatibility with food safety regulations.^[56] Silver nanoparticles (AgNPs) represent a prominent mechanism, exerting antimicrobial effects through the release of silver ions that disrupt bacterial cell membranes, generate reactive oxygen species, and interfere with DNA replication, providing broad-spectrum activity against pathogens like Escherichia coli and Staphylococcus aureus. When incorporated into biopolymer films such as chitosan or alginate, AgNPs demonstrate zones of inhibition exceeding 10 mm in agar diffusion tests, effectively reducing microbial counts on food surfaces. Organic acids, such as sorbic acid, function by lowering pH and disrupting microbial cell membranes, often integrated into edible coatings to inhibit fungi and bacteria in acidic food environments; for instance, sorbic acid-loaded chitosan films have shown sustained release over 10 days, maintaining antimicrobial potency. Bacteriocins, like nisin, target Gram-positive bacteria by forming pores in cell membranes, leading to lysis; nisin-embedded films can achieve up to 2.5 log CFU/g reduction in Listeria monocytogenes populations.^[57]^[56] These systems are particularly applied to fresh meats and ready-to-eat foods, where contamination risks are high. In fresh poultry, such as chicken drumsticks, films incorporating nisin or potassium sorbate reduce aerobic plate counts by 2-3 log CFU/g over storage, delaying spoilage and maintaining sensory quality. For ready-to-eat products like cheese or processed meats, antimicrobial packaging with bacteriocins or organic acids extends shelf life by inhibiting Listeria growth, with reported reductions of 2-4 log CFU in soft cheeses during refrigerated storage. Effectiveness is routinely evaluated through zone of inhibition assays, which confirm broad-spectrum inhibition against key foodborne pathogens, including Salmonella and Listeria, with inhibition zones varying from 8-20 mm depending on agent concentration.^[56]^[57] Integration of antimicrobials occurs via migratory or non-migratory approaches within polymer matrices. Migratory systems allow controlled diffusion of agents like nisin or sorbic acid from films into the food, ensuring direct contact and prolonged activity, as seen in polyethylene or starch-based packaging. Non-migratory systems immobilize agents such as AgNPs or bacteriocins on the polymer surface, providing contact-kill effects without significant migration, which is advantageous for regulatory compliance in low-migration applications like polypropylene films. To align with clean-label trends, natural alternatives like essential oils (e.g., oregano or clove) are increasingly used, incorporated into biopolymer films to achieve similar broad-spectrum inhibition through membrane disruption, with zones of inhibition up to 15 mm against S. aureus and E. coli. Release timing from these systems can be tuned to match product shelf life, though detailed delivery methods vary by application. Recent developments as of 2025 emphasize the use of plant-derived phenolics from agricultural waste in polylactic acid (PLA) films, enhancing antimicrobial efficacy against multidrug-resistant bacteria while promoting biodegradability.^[56]^[57]^[58]

Controlled Release Mechanisms

Controlled release mechanisms in active packaging enable the gradual delivery of active compounds, such as antimicrobials or flavors, from the packaging material into the food product to maintain quality and extend shelf life. These systems primarily operate through diffusion-based processes where active agents migrate from a polymer matrix to the food interface, governed by concentration gradients and material properties. For instance, essential oils like cinnamon can diffuse from agar/polyvinyl alcohol films, providing sustained release over time. Microencapsulation represents another key approach, involving the entrapment of active compounds within micro- or nanocapsules, such as thymol-loaded nanofibers, which protect the agents and control their release via erosion or diffusion of the shell.^[59] Cyclodextrin inclusion complexes further enhance precision by forming host-guest structures that encapsulate hydrophobic molecules, like allyl isothiocyanate, releasing them in response to environmental humidity changes.^[59] Applications of these mechanisms span flavor enhancement and preservation in various foods. In snack packaging, controlled release facilitates flavor dispensing, where volatile compounds adsorb onto or desorb from the packaging to infuse products like potato chips, improving sensory attributes without over-flavoring.^[60] For dairy products, such systems release preservatives like essential oils or α-tocopherol to inhibit lipid oxidation and microbial growth, as seen in films that reduce Listeria monocytogenes counts by up to 4.5 log CFU/g in cheese.^[61] These approaches often aim for zero-order kinetics, achieving steady release rates independent of remaining agent concentration, which is ideal for consistent protection throughout storage.^[62] The effectiveness of controlled release mechanisms is demonstrated by their ability to extend agent delivery over periods of 1-6 months in suitable applications, such as dry or low-moisture foods, thereby prolonging overall shelf life. A notable example is the use of allyl isothiocyanate encapsulated in metal-organic frameworks for meat preservation, which maintains antimicrobial activity for up to 24 days under refrigerated conditions, scalable to longer durations in ambient storage scenarios.^[63] In dairy contexts, similar systems with natural antimicrobials have been shown to delay spoilage, enhancing product stability without altering sensory profiles.^[64] Stimuli-responsive triggers allow for on-demand release, optimizing efficiency. pH-sensitive systems, such as chitosan-based films, activate in acidic food environments like fruit exudates to release agents precisely when needed.^[65] Temperature triggers, exemplified by poly(N-isopropylacrylamide) hydrogels that swell at 37°C, enable heat-activated delivery during transport or storage fluctuations. Light-activated mechanisms, including UV-responsive nanocapsules containing thyme oil, provide controlled desorption upon exposure, suitable for light-sensitive packaging applications. Recent innovations as of 2025 include dual-responsive systems combining pH and temperature sensitivity in bio-based nanocomposites, improving targeted release for perishable goods like meat and dairy. These antimicrobial payloads integrate seamlessly with broader preservation strategies, ensuring targeted efficacy.^[65]^[62]

Intelligent and Tracking Technologies

Intelligent packaging technologies, such as those involving tracking and monitoring, complement active packaging by providing real-time data on environmental conditions and product integrity, enabling better management of interactions that extend shelf life. These systems monitor without directly releasing or absorbing substances, distinguishing them from core active mechanisms.

RFID Integration

Radio-frequency identification (RFID) integration in intelligent packaging systems, often used alongside active packaging, enables wireless tracking and data storage to monitor product conditions throughout the supply chain, enhancing traceability and quality control for perishable goods. RFID tags embedded in packaging materials capture and transmit information such as location, environmental exposures, and handling events without physical contact, supporting dynamic interactions between the package and external readers. This technology provides actionable insights for logistics and safety in conjunction with active systems.^[66] RFID mechanisms in intelligent packaging primarily utilize passive tags, which operate without an internal power source and are powered by the reader's electromagnetic field to store and retrieve data on variables like temperature or location. These tags, typically operating in the ultra-high frequency (UHF) band (860-960 MHz), offer a cost-effective solution for widespread deployment. Active RFID tags, in contrast, incorporate batteries to actively transmit signals, enabling longer read ranges and higher data rates for more demanding applications. Chipless RFID options further reduce costs by eliminating silicon chips, instead encoding data through the tag's physical structure or printed patterns, making them ideal for disposable packaging where affordability is critical.^[66]^[67]^[68] In applications, RFID integration excels in supply chain management for perishables, such as fresh produce or seafood, where tags track items from farm to retailer, ensuring compliance with storage conditions and minimizing spoilage. For instance, in cold chain logistics, RFID systems facilitate real-time alerts for breaches, such as temperature excursions, allowing rapid intervention to prevent waste estimated at up to 20% in food distribution. This capability supports automated inventory and reduces manual checks, streamlining operations in food logistics.^[66]^[69] The effectiveness of RFID in intelligent packaging stems from its read range, which can extend up to 10 meters for UHF passive tags, allowing non-line-of-sight scanning in warehouses or transport vehicles. Integration with sensors enhances this by enabling active data transmission of condition-specific metrics, such as humidity or integrity, directly from the tag to centralized systems for predictive analytics. The EPC Gen2 protocol standardizes these operations, ensuring interoperability across UHF RFID devices in food logistics by defining air interface communication for reliable tag-reader interactions.^[66]^[70]^[71]

Bar Code and Security Features

Bar codes and security features in intelligent or conventional packaging, integrated with active systems, primarily serve to enhance traceability and prevent counterfeiting through printed or embedded visual elements that can be verified without advanced equipment. Traditional one-dimensional (1D) bar codes, such as UPC codes, encode limited numerical or alphanumeric data for basic product identification and inventory tracking along the supply chain. In contrast, two-dimensional (2D) codes like QR codes offer higher data capacity, storing up to thousands of characters to link products to digital databases for detailed authentication and consumer interaction via smartphone apps. These mechanisms integrate seamlessly with packaging materials, enabling real-time verification of origin, batch details, and handling history.^[72] Security enhancements often incorporate holograms and frangible seals to provide tamper-evident protection. Holograms use diffractive optics to create complex, iridescent images that are difficult to replicate, serving as overt authentication markers on labels or films. Frangible seals, designed to break irreversibly upon unauthorized access, incorporate micro-perforations or brittle materials that leave visible evidence of tampering, ensuring product integrity from manufacturer to end-user. These features are particularly vital in sectors prone to fraud, such as pharmaceuticals, where serialized QR codes and holograms track drug authenticity to combat counterfeit medications that pose health risks. Similarly, in luxury goods like high-end spirits and accessories, unique bar code serialization combined with holographic elements prevents illicit replication, protecting brand value and consumer trust.^[73]^[74] The effectiveness of these systems is evidenced by high scan reliability and integration capabilities. Modern 2D bar codes and QR codes achieve scan accuracies exceeding 99% under standard conditions, minimizing errors in supply chain verification and reducing manual data entry risks. When paired with mobile applications, they allow instant cross-referencing against manufacturer databases, flagging discrepancies in seconds and deterring counterfeiting through serialized uniqueness. For instance, pharmaceutical packaging with QR codes has been shown to streamline regulatory compliance while enhancing patient safety by confirming product legitimacy.^[75] Distinctions exist between static and dynamic types of these features. Static bar codes remain unchanged throughout the product lifecycle, relying on fixed encoding for consistent readability. Dynamic variants, however, employ functional inks that alter appearance in response to environmental exposure, such as thermochromic inks changing color to indicate time-temperature abuse or photochromic elements activating under UV light for added security layers. These dynamic bar codes, often in 2D formats, enable evolving data output—scannable to reveal condition-specific information—further supporting traceability without electronic components like RFID.^[76]

Specialized and Mechanical Protections

Microwave-Active Packaging

Microwave-active packaging incorporates materials that interact with microwave energy to enhance food heating, cooking, or protection during microwave oven use. Central to this technology are susceptors, typically thin films of metallized materials such as aluminum deposited on substrates like paperboard or polyester, which absorb microwave radiation and convert it into localized heat through resistive heating. This mechanism allows susceptors to achieve surface temperatures up to approximately 200–300°C, enabling browning and crisping effects that mimic conventional oven results. Additionally, shielding layers, often composed of thicker metallic films or foils, reflect microwaves to prevent overheating in sensitive areas, directing energy more uniformly to the food product.^[77]^[78]^[79]^[80]^[81] These components find primary applications in ready-to-eat meals and frozen foods, where they address common microwave heating issues like uneven distribution and sogginess. For instance, susceptors in pizza or fried food packaging promote crisp textures by elevating the base temperature beyond the boiling point of water, while shielding prevents overcooking of delicate toppings or sauces in multi-component dishes. This targeted energy interaction improves overall cooking efficiency, reducing preparation time and enhancing sensory qualities without requiring additional utensils.^[82]^[83]^[84] The effectiveness of microwave-active packaging is evidenced by its ability to raise food surface temperatures sufficiently for Maillard reactions, which are essential for flavor development and texture, while standard microwave heating alone typically limits surfaces to around 100°C. Safety standards, enforced by bodies like the FDA and European Commission, rigorously test these materials for chemical migration, ensuring that substances from susceptors or shields do not exceed permissible limits under high-heat conditions, thereby minimizing risks to consumer health.^[85]^[86]^[87] Innovations as of 2021 include active steaming films that integrate susceptor elements with vented or pressure-building structures, generating internal vapor during microwaving to cook foods like vegetables or seafood more evenly and retain moisture. These films, often made from polyethylene or polypropylene, allow controlled steam release, extending shelf life and simplifying preparation for fresh or frozen products.^[88]^[89]^[90]

Shock and Vibration Control

No content retained due to scope misalignment with food-focused active packaging; mechanical protections better suited to general packaging topics covered elsewhere in broader literature.

Emerging Developments

Nanotechnology Applications

Nanotechnology has revolutionized active packaging by incorporating nanoscale materials to enhance antimicrobial properties, gas barrier performance, and sensing capabilities, enabling more effective preservation of food and other perishables. These materials, typically under 100 nanometers in size, interact at the molecular level to provide functionalities that traditional packaging cannot achieve, such as targeted release or detection without compromising structural integrity. Developments from 2019 to 2024 have focused on integrating nanomaterials like metal nanoparticles, clays, and carbon-based structures into packaging films and coatings, with continued advancements into 2025 including broader commercialization of nanosensors. One key mechanism involves nano-silver particles, which release silver ions to disrupt bacterial cell walls and inhibit microbial growth in packaging environments. For instance, nano-silver incorporated into polyethylene films has demonstrated a 99% reduction in Escherichia coli and Staphylococcus aureus populations on food surfaces after 24 hours of exposure. This antimicrobial action is particularly effective in oxygen-scarce conditions, extending shelf life for perishable items like meat and dairy. Similarly, nano-encapsulated essential oils, such as those from thyme or oregano, use lipid or polymer nanocapsules to control the release of volatile compounds, providing sustained antimicrobial effects while minimizing flavor alterations in packaged goods. Nano-clays, such as montmorillonite, serve as gas barriers by creating tortuous paths that impede oxygen and moisture permeation through polymer matrices. Layered silicate nanoclay additions to low-density polyethylene have improved oxygen barrier properties by up to 100-200%, significantly reducing oxidation in oxygen-sensitive foods like snacks and baked goods. This enhancement is attributed to the high aspect ratio of the clay platelets, which exfoliate within the polymer to form impermeable layers. Carbon nanotubes, with their conductive properties, enable the development of nanosensors that detect spoilage indicators like volatile amines or ethylene gas in real-time. Functionalized multi-walled carbon nanotubes embedded in packaging films can change color or electrical conductivity upon exposure to these compounds, alerting consumers to quality degradation. Titanium dioxide (TiO2) nanoparticles act as photocatalysts under UV light to decompose ethylene, a ripening hormone that accelerates fruit spoilage. In active packaging for produce, nano-TiO2 coatings on films have reduced ethylene levels by over 90% in enclosed spaces, thereby delaying senescence in climacteric fruits like apples and bananas. This application leverages the photocatalytic generation of reactive oxygen species to break down the gas without leaving harmful residues. As of 2025, nano-TiO2 integrations have seen pilot-scale use in commercial fruit packaging to further extend shelf life. Despite these advances, challenges persist in ensuring nanomaterial safety, particularly regarding migration into food. Studies indicate that while most nano-silver and nano-clay formulations comply with migration limits under normal storage, prolonged exposure or acidic conditions can exceed thresholds, necessitating rigorous testing. The European Union's regulations under Regulation (EU) No 10/2010 require specific authorizations for nanomaterials in food contact materials, emphasizing toxicological assessments to mitigate potential health risks from ingestion. Ongoing research prioritizes biocompatible coatings to address these concerns while maintaining efficacy.

Sustainable and Bio-Based Innovations

Sustainable and bio-based innovations in active packaging emphasize the use of renewable, environmentally friendly materials to extend food shelf life while minimizing ecological impact. These advancements, particularly from 2020 to 2025, focus on bio-based polymers such as chitosan and polylactic acid (PLA), which incorporate natural compounds to provide antimicrobial and antioxidant functions without relying on synthetic additives. Chitosan, derived from chitin in crustacean shells or fungal sources, exhibits inherent antimicrobial properties by disrupting bacterial cell membranes, and recent formulations have enhanced its efficacy through incorporation of essential oils or flavonoids for broader spectrum activity in food preservation.^[91] Similarly, PLA, a biodegradable polyester from fermented plant starches like corn, has been modified with natural antioxidants such as plant-derived polyphenols to prevent oxidation in perishable goods.^[92] These mechanisms align with circular economy principles by enabling material recovery and reducing dependency on fossil-based plastics.^[93] Applications of these bio-based systems include compostable oxygen absorbers tailored for organic produce packaging, where sachets or films embedded with natural reductants like catechins from green tea extract oxygen levels to below 0.01%, extending shelf life for fruits and vegetables while allowing full decomposition in industrial composting facilities. This approach significantly reduces plastic waste in food supply chains, as bio-based absorbers degrade alongside organic waste streams, avoiding landfill accumulation and microplastic pollution. Phenolic extracts from plants, such as those from grape seeds or rosemary, serve as potent natural preservatives when integrated into these films; they inhibit microbial growth and lipid oxidation through free radical scavenging, matching or exceeding the performance of synthetic antioxidants in maintaining product freshness for up to several weeks.^[94]^[95] In terms of effectiveness, bio-based active packaging achieves biodegradation rates of 90% within six months under controlled composting conditions, comparable to industrial standards and surpassing many conventional plastics that persist for centuries. This rapid degradation supports soil health without releasing harmful residues, as verified by ISO 14855 testing protocols. Market trends indicate a strong shift toward bio-actives, with the global bio-based packaging sector projected to grow from USD 11.82 billion in 2025 to USD 34.4 billion by 2034, driven by consumer demand for eco-friendly solutions and regulatory incentives for recyclability. Integration with circular economy models, such as closed-loop recycling of PLA composites, further promotes resource efficiency and positions bio-based innovations as a cornerstone of sustainable food packaging by 2025.^[96]^[38]

Regulations and Broader Applications

Regulatory Frameworks

Active packaging materials and systems are subject to stringent regulatory oversight worldwide to ensure they do not pose risks to human health, particularly when used in food contact applications. In the United States, the Food and Drug Administration (FDA) regulates active packaging components as food contact substances (FCS), requiring them to be either approved food additives or generally recognized as safe (GRAS) for their intended use.^[97] Substances expected to migrate into food must undergo pre-market approval via Food Contact Notifications (FCN) or GRAS self-determination, with the FDA evaluating safety based on toxicological data and exposure assessments.^[98] In the European Union, the overarching Framework Regulation (EC) No 1935/2004 governs all food contact materials, including active packaging, mandating that they must not transfer constituents to food in quantities that could endanger health, alter food composition, or cause deterioration in taste, odor, or texture. This regulation is supplemented by specific rules under Regulation (EC) No 450/2009 for active and intelligent materials, which requires authorization of active components by the European Food Safety Authority (EFSA) following risk assessments.^[99] For oxygen scavengers, a common active packaging technology, both FDA and EU approvals are granted on a case-by-case basis; for instance, the FDA has issued FCNs for systems like iron-based absorbers, while EFSA has authorized mixtures involving iron, sodium chloride, and silica gel, provided migration remains below safety thresholds.^[100]^[101] Testing requirements emphasize migration limits and safety evaluations to verify compliance. Under EU rules, overall migration from active packaging must not exceed 10 mg/dm², assessed using standardized simulants and conditions simulating real-use scenarios as per EN 1186 methods.^[102] Specific migration limits apply to individual substances, and toxicological assessments for active components involve evaluating genotoxicity, carcinogenicity, and reproductive toxicity through EFSA's scientific opinions.^[103] The FDA similarly requires quantitative exposure estimates and toxicological profiles, often referencing the Threshold of Toxicological Concern (TTC) approach for data-poor substances.^[104] International variations are addressed through guidelines like those from the Codex Alimentarius Commission, which promote harmonized standards for food packaging safety, emphasizing that materials should not contaminate food and recommending risk-based assessments for novel technologies. Post-2020 updates have focused on nanomaterials in active packaging; the EU's Recommendation 2011/696/EU defines nanomaterials and requires their explicit labeling and risk evaluation under REACH and food contact regulations, while the FDA oversees them under existing FCS rules without a separate nano-specific framework but with enhanced post-market surveillance.^[105]^[106] In 2025, the EU adopted the Packaging and Packaging Waste Regulation (EU) 2025/40, effective February 2025, which sets targets for packaging waste reduction (5% by 2030, 10% by 2035, 15% by 2040) and promotes recyclability and reuse, applying to active packaging by requiring minimum recycled content and minimizing environmental impact. Additionally, amendments to EU plastic food contact material regulations entered into force in March 2025, broadening scope and updating safety requirements for active components.^[107]^[108] Compliance challenges include mandatory labeling of active components to inform consumers and regulators, such as declarations of releasing or absorbing substances under EU rules, which can vary by jurisdiction and complicate global supply chains.^[109] Efforts toward harmonization are supported by the World Trade Organization's (WTO) Agreement on Technical Barriers to Trade (TBT), which encourages alignment of packaging standards to facilitate international trade while protecting health, though discrepancies in migration testing and authorization persist across regions.^[110]

Industry Applications

Active packaging has found extensive application in the food sector, which held 27.8% of the global market share in 2023 due to its role in preserving perishable items and minimizing spoilage.^[111] In particular, modified atmosphere packaging (MAP) is commonly employed for fresh meats, where it replaces ambient air with a controlled gas mixture—typically high in carbon dioxide and low in oxygen—to inhibit microbial growth and oxidation, thereby extending shelf life; for example, from 7 days to 21 days for poultry and from 4 days to 8 days for red meat under traditional packaging.^[112] This technology has been pivotal in retail and supply chain operations, allowing for longer distribution times without compromising product quality or safety.^[113] In the pharmaceutical industry, active packaging ensures the integrity of temperature-sensitive products, such as vaccines, which require strict maintenance between 2°C and 8°C to preserve efficacy during global distribution.^[114] Systems incorporating phase-change materials and real-time monitoring devices actively regulate thermal fluctuations, preventing denaturation in biologics and injectables.^[115] Additionally, metal-chelating agents integrated into packaging films bind free ions that could catalyze degradation in injectable formulations, enhancing stability and extending usability.^[116] Beyond food and pharmaceuticals, active packaging addresses specific challenges in cosmetics and electronics. For cosmetics, moisture-adsorbing sachets or films actively capture humidity within packages, preventing clumping, separation, or microbial proliferation in products like creams and powders, thus maintaining efficacy throughout shelf life.^[117] In the electronics sector, volatile corrosion inhibitors (VCIs) embedded in packaging materials release protective vapors that form a molecular barrier on metal surfaces, shielding circuit boards, connectors, and components from rust and oxidation during storage and transit.^[118] Overall, these implementations yield economic benefits, including significant reduction in food waste across supply chains by optimizing preservation and reducing losses at retail and consumer levels.^[119]

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Packaging materials and technologies for microwave applications
Jan 31, 2022 · The introduction of a functional feather to microwave packaging tends to improve the microwaving efficiency such as susceptor and shielding in ...
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Shielding and field modification – thick metal films - ResearchGate
Thick metal elements produce shielding and field modification when incorporated into microwave packages. Designs with materials that maintain conductivity ...
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Microwavable Food Packaging - ScienceDirect.com
Thus, microwavable active packaging is designed to ameliorate the heating behaviour of the food by shielding, field modification and the use of susceptors ( ...
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Microwave packaging is powering the ready-to-eat food
Apr 24, 2025 · Microwave-active packaging interacts directly with microwave energy to optimise the heating process. These materials often include susceptors, ...
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Shieltron microwave packaging delivers hot topping on cold ice cream
Mar 18, 2017 · The result was achieved using Shieltron's in-moulds, which incorporate shielding layers that selectively shield different parts of the same ...
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Susceptors in microwave cavity heating: Modeling and ...
Without a susceptor, the food contact surface temperature will not reach much above 100 °C in microwave heating, preventing crisping or color developments in ...
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Microwave oven safety - CSIRO
Susceptors absorb microwave energy and heat food mainly by direct contact. Susceptor materials have been tested both for migration levels of undesirable ...
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[PDF] Effect of Microwave Heating on The Migration of Additives From PS ...
Both the FDA regulations and the European Community (EC) have complex regulations to control potentially harmful migrating substances from food packaging ...
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KM's Packaging launches new steam packaging - Food Engineering
May 15, 2017 · This new K Steam packaging film is ideal for microwave steam cooking of fresh vegetables, fish and seafood; it enables pressure to build within ...
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ProAmpac Pioneers Recyclable Mono-Material for Microwave ...
Apr 11, 2022 · This pioneering polyethylene-based film fulfills the market need for a recyclable packaging option that withstands the demands of a microwave ...
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Steam packaging film extends product shelf-life - Food Manufacture
Jun 30, 2017 · The K Steam packaging film is designed for microwave steam cooking of fresh vegetables, fish and seafood. It is said to enable pressure to build ...<|control11|><|separator|>
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Chitosan for food packaging: Recent advances in active and ...
Typical examples of active packaging are oxygen scavengers, carbon dioxide emitters/absorbers, moisture absorbers, ethylene absorbers, ethanol emitters, ...Chitosan For Food Packaging... · 3. Mechanical Properties Of... · 5. Functional Properties Of...<|control11|><|separator|>
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Active PLA Packaging Films: Effect of Processing and the Addition of ...
Dec 11, 2021 · The performance characteristics of polylactic acid (PLA) as an active food packaging film can be highly influenced by the incorporation of ...
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Emerging trends in biomaterials for sustainable food packaging
Jan 15, 2024 · The market for bioplastics is expected to reach USD 2.87 million in 2025 ... A burgeoning market for bioplastic packaging is being addressed by ...
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Non-iron oxygen scavengers in food packaging - RSC Publishing
Sep 18, 2025 · This review critically examines recent developments in natural and synthetic non-iron oxygen scavengers, including antioxidants (ascorbic acid ...
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Biodegradable active materials containing phenolic acids for food ...
Aug 1, 2022 · Phenolic acids are plant metabolites that can be found in multiple plant extracts and exhibit antioxidant and antimicrobial properties.
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Biodegradability standards for carrier bags and plastic films in ... - NIH
May 23, 2018 · ... biodegradation rate of 90% following six months of exposure. Requirements for test material disintegration and toxicity testing, based on ...
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Bio-Based Packaging Market Surges USD 11.82 Bn in 2025 at ...
Jul 24, 2025 · The global bio-based packaging market is projected to reach USD 34.4 billion by 2034, expanding from USD 11.82 billion in 2025, at an annual ...<|separator|>
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Food Packaging & Other Substances that Come in Contact with Food
Jul 24, 2024 · Under federal law, a food contact substance that is a food additive must be authorized for that use before it is marketed in the U.S. Such ...Packaging & Food Contact... · Understanding How the FDA...Missing: active | Show results with:active<|separator|>
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Regulatory Status of Components of a Food Contact Material - FDA
Feb 21, 2018 · The overall regulatory status of a food contact material is dictated by the regulatory status of each individual substance that comprises the article.Missing: active | Show results with:active
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The Regulation of Active and Intelligent Food Packaging in the U.S. ...
Apr 14, 2022 · Active packaging systems protect food from contamination or degradation either by creating a barrier to outside conditions or controlling the atmosphere within ...Missing: electronics pharmaceuticals
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[PDF] Finding of No Significant Impact for Food Contact Notification No. 2302
Jul 24, 2023 · The alternative of not approving the notified action would result in the continued use of other oxygen scavenging systems that the FCS would ...
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EFSA authorizes iron-based oxygen absorbers for food contact
May 6, 2013 · The European Food Safety Authority (EFSA) authorized mixtures of iron based oxygen absorber systems comprising iron, sodium chloride, water, silica gel, ...
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Migration Testing of Packaging and Food Contact Materials - Eurofins
Sep 6, 2024 · 1935/2004 requires that such migration must not endanger human health, bring about no deterioration of organoleptics and must not change the ...
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Assessing Compliance with EU Food-Contact Regulations
Oct 10, 2023 · The overarching regulation governing food-contact materials (FCMs) in the European Union (EU) is the Framework Regulation, (EC) No. 1935/2004.
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Generally Recognized as Safe (GRAS) - FDA
Oct 17, 2023 · Information about how FDA regulates food additives that are generally recognized as safe or "GRAS."GRAS Substances (SCOGS... · GRAS Notification Program · GRAS Notice InventoryMissing: active | Show results with:active
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Nanomaterials - Food Safety - European Commission
The European Union has put in place regulations to properly define nanomaterials and assess any health and environmental risks that may result from their use ...
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[PDF] FDA Regulation of Nanotechnology - Beveridge & Diamond PC
EU legislation to require food using such nanomaterials to be labeled as such is pending at the time of this writing. 94. D. POST-MARKETING SURVEILLANCE. FDA ...<|separator|>
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Packaging compliance: three challenges | Enhesa
Dec 6, 2023 · The third challenge reshaping packaging product compliance is a lack of harmonization. Obligations vary widely across countries – and even at ...
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Agreement on Technical Barriers to Trade - WTO
... compliance is mandatory. It may also include or deal exclusively with terminology, symbols, packaging, marking or labelling requirements as they apply to a ...Missing: challenges labeling
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Active Packaging Market Size, Share, Trends, Analysis, 2032
The active packaging market size is projected to grow from $15.21 billion in 2023 to $24.74 billion by 2032, at a CAGR of 5.64% during the forecast period.
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How long is food shelf life extended by MAP - Peak Gas Generation
Jan 17, 2020 · The shelf life extension provided by a modified atmosphere could be anything from days to years. Below are some examples.
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Packaging meat and poultry to extend shelf life - Linde Gas
Modified atmosphere packaging (MAP) can extend the shelf life of meat and poultry without altering their physical or chemical properties or adding any ...
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Pharmaceutical Temperature Controlled Packaging Solutions ...
Aug 21, 2025 · Vaccines are often highly sensitive to temperature variations. They require precise temperature control to maintain their efficacy. This ...<|separator|>
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Pharmaceutical Temperature-Controlled Packaging Solutions ...
Sep 19, 2025 · The market for pharmaceutical temperature-controlled packaging solutions encompasses a wide range of products and services, including insulated ...
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Photo‐Curable Metal‐Chelating Coatings Offer a Scalable Approach to Production of Antioxidant Active Packaging
### Summary of Mechanisms and Applications of Metal Chelation in Active Packaging
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NEW! Moisture Adsorbing Active Packaging - ProAmpac
Jan 24, 2024 · This innovative product has a high moisture-adsorbing capacity and is set to revolutionize moisture protection in flexible packaging.
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Active Packaging Finds a Foothold in Food, Pharma, and Ecommerce
Apr 15, 2025 · Valued at $22.17 billion in 2024, the market is projected to reach $45.69 billion by 2034, expanding at a strong CAGR of 7.5%. The driving ...
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How Packaging Can Help with Food Waste - icpg
Aug 2, 2023 · ReFED estimates that active and intelligent packaging can help divert 1.1 million tons of food waste & save 314 billion gallons of water. Active ...