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Limp

Definition

A limp, medically termed an antalgic gait, is an abnormal walking pattern resulting from pain in the lower extremity or back, characterized by a shortened stance phase on the affected side to minimize weight-bearing and discomfort, leading to an uneven, halting progression.^[1]

Clinical Characteristics

This gait abnormality is the most common form of disrupted locomotion, often manifesting as favoring one leg and reducing overall walking speed.^[2] Less frequently, limps may arise from non-painful factors like muscle weakness or neuromuscular imbalances, though these often overlap with painful triggers in clinical presentation.^[2]

Introduction

Definition

A limp is defined as an asymmetric abnormality in gait, characterized by reduced weight-bearing on the affected leg due to pain, weakness, stiffness, or instability in the lower extremity.^[3] This deviation from normal walking patterns results in an uneven, labored progression that minimizes stress on the involved side.^[4] Key features of a limp include a shortened stance phase on the affected limb, where the foot spends less time in contact with the ground compared to the swing phase, often as a protective mechanism.^[5] In instances involving hip abductor weakness, such as certain pathologies, a Trendelenburg pattern may emerge, marked by a compensatory lateral trunk lean toward the affected side during the stance phase to stabilize the pelvis.^[6] Limps are broadly categorized as antalgic, which are primarily pain-avoiding and feature this abbreviated stance duration, or non-antalgic, arising from structural or neuromuscular issues without dominant pain influence.^[7] The term "limp" originates from the Old English limpan, meaning to walk unevenly or to occur unexpectedly, evolving through Middle English to describe faltering movement.^[8] In medical contexts, it has long denoted gait deviations, frequently linked to lower extremity conditions like hip involvement.^[1]

Clinical Characteristics

A limp manifests as an asymmetry in gait, often presenting with primary symptoms centered on pain localized to the lower extremities, such as the hip, knee, or foot, which may arise acutely following minor trauma or develop chronically over time.^[1] Associated features can include swelling around the affected joint, fever indicating systemic involvement, or fatigue that exacerbates the discomfort during ambulation.^[9] In pediatric cases, pain may be intermittent and nocturnal, leading to irritability or refusal to bear weight, particularly in younger children.^[10] Gait variations are key observable features, with the antalgic limp being the most common, characterized by a shortened stance phase on the affected side to minimize pain, resulting in a quick, uneven step.^[1] Other patterns include the Trendelenburg gait, involving a compensatory lateral trunk shift toward the affected side due to hip abductor weakness; circumduction, where the leg swings outward in an arc to avoid flexion; and steppage gait, marked by exaggerated knee lift to compensate for foot drop.^[9] These alterations disrupt the normal cyclical and symmetric walking pattern, often becoming more pronounced during prolonged activity.^[11] Physical signs frequently observed include asymmetry in leg length, which contributes to pelvic tilt and uneven weight distribution; muscle atrophy in the affected limb from disuse; and joint effusion presenting as localized swelling or warmth.^[10] Patients may rely on assistive devices such as crutches to offload the painful side, further highlighting the asymmetry during examination.^[1] In children, additional signs like tiptoe walking or a flexed hip posture can indicate compensatory mechanisms.^[9] The impact on patients extends beyond physical limitations, with reduced mobility increasing the risk of falls and restricting daily activities such as walking to school or participating in sports.^[10] In children, a persistent limp can lead to psychological effects, including anxiety or reluctance to engage socially due to self-consciousness about the gait abnormality.^[11] Overall, these characteristics underscore the need for prompt recognition to mitigate long-term functional impairments.^[1]

Etiology

Infectious Causes

Infectious causes of limp primarily involve microbial invasion of bones, joints, or surrounding tissues, triggering an acute inflammatory response that leads to synovial effusion, joint instability, and pain during weight-bearing activities. This pathophysiology begins with pathogen entry via hematogenous spread, direct inoculation, or contiguous extension from adjacent infections, resulting in the release of inflammatory mediators such as cytokines and proteases that cause edema, fibrin deposition, and potential cartilage degradation. In children, these infections often manifest as a sudden refusal to bear weight, while in adults, they may present more insidiously with progressive gait abnormality.^[12]^[13]^[7] Septic arthritis, a medical emergency, occurs when bacteria invade the synovial fluid, leading to rapid joint destruction through enzymatic breakdown of articular surfaces and accumulation of pus that impairs joint function and causes a limp. The most common pathogen in children is Staphylococcus aureus, accounting for approximately 37% to 56% of cases, often following bacteremia from skin or respiratory infections. Adults, particularly intravenous drug users and immunocompromised individuals, face higher risks from pathogens like Staphylococcus aureus, gram-negative bacilli, or fungi, with associated systemic signs including fever and local erythema over the affected joint, such as the hip or knee.^[12]^[14]^[15]^[16] Osteomyelitis, an infection of the bone marrow and cortex, induces severe pain and periosteal elevation due to subperiosteal abscess formation, often resulting in a limp from localized tenderness and swelling in the lower extremities. In children, it typically arises from hematogenous seeding of bacteria, with Staphylococcus aureus as the predominant pathogen, affecting metaphyseal regions of long bones like the femur or tibia. In adults, contiguous spread from adjacent soft tissue infections or diabetic foot ulcers is more common, involving similar pathogens but with a higher incidence of polymicrobial involvement.^[13]^[17]^[18]^[19] Other infections contributing to limp include Lyme disease, caused by Borrelia burgdorferi transmitted via tick bites, which provokes a migratory arthritis through immune-mediated synovial inflammation, commonly affecting large joints like the knee and leading to intermittent limping. Viral infections, such as parvovirus B19, can trigger transient synovitis via reactive immune responses, resulting in self-limited joint effusion and a limp, particularly in children. Tuberculous arthritis, due to Mycobacterium tuberculosis, presents chronically with low-grade fever and insidious joint swelling, causing a gradual limp from caseating granuloma formation and bone erosion, often in the hip or knee.^[20]^[21]^[22]^[23]^[24]

Mechanical and Traumatic Causes

Mechanical and traumatic causes of limp arise from physical disruptions to the musculoskeletal system, often resulting in immediate or progressive gait abnormalities due to pain, instability, or structural misalignment. These etiologies encompass acute injuries such as fractures, sprains, and contusions, as well as chronic mechanical issues like joint incongruities or limb asymmetries. Unlike infectious or inflammatory processes, these conditions typically lack systemic symptoms and stem directly from mechanical overload, direct impact, or developmental anomalies.^[1] Trauma represents a primary cause of acute limp, with fractures, sprains, and contusions leading to an antalgic gait characterized by shortened stance phase on the affected side to minimize pain. Femoral neck fractures, particularly prevalent in the elderly following low-energy falls, disrupt weight-bearing and cause a pronounced limp due to hip instability and pain. Sprains of ligaments around the ankle or knee, often from inversion injuries, result in swelling and tenderness that impair normal propulsion, while soft tissue contusions from direct blows to the thigh or calf produce localized hematoma and reduced mobility, prompting a protective limp. These injuries exhibit immediate onset post-trauma, with resolution dependent on healing and rehabilitation.^[1]^[25]^[26]^[27] Slipped capital femoral epiphysis (SCFE) is a notable traumatic or mechanical cause in adolescents, involving posterior displacement of the femoral head relative to the neck through the growth plate, often triggered by minor trauma in susceptible individuals. It predominantly affects obese males aged 10-16 years, with an incidence of approximately 10.8 per 100,000 children, and is bilateral in 20-40% of cases. The resulting varus deformity alters hip mechanics, leading to thigh or knee pain and an external rotation limp during weight-bearing.^[28]^[29]^[30] Leg length discrepancy (LLD), whether congenital or acquired, induces a mechanical limp by forcing compensatory pelvic tilt and asymmetric loading of the lower limbs. Congenital forms, such as hemihypertrophy, present with one limb shorter from birth, while acquired discrepancies often follow fractures or growth arrests, with differences exceeding 1 cm causing noticeable shortening of the stride on the affected side. This biomechanical imbalance increases stress on the longer limb's joints and spine, perpetuating the limp.^[31]^[32] Other mechanical causes include osteochondritis dissecans (OCD), where subchondral bone and overlying cartilage in the knee separate, forming loose fragments that irritate the joint and provoke pain with activity, resulting in a limp. Foreign bodies lodged in joints, such as plant thorns or glass fragments, can elicit chronic synovitis and effusion, mimicking trauma but causing persistent mechanical obstruction to smooth motion.^[33]^[34] The pathophysiology of limp in these conditions involves altered biomechanics, where structural disruption or asymmetry shifts the body's center of gravity, prompting compensatory strategies like reduced weight-bearing or circumduction to avoid pain and maintain balance. This leads to inefficient energy expenditure and potential secondary strain on contralateral structures.^[1]^[31]

Inflammatory Causes

Inflammatory causes of limp primarily involve non-infectious processes that lead to synovial inflammation in weight-bearing joints such as the hips and knees, resulting in pain, effusion, and restricted motion that manifests as an antalgic gait.^[35] The underlying pathophysiology is driven by cytokine-mediated immune responses, including elevated levels of pro-inflammatory cytokines like interleukin-6 and tumor necrosis factor-alpha, which promote synovial hyperplasia, vascular permeability, and joint effusion; this inflammation disrupts normal joint mechanics and induces compensatory limping to minimize pain during weight-bearing.^[36] Unlike infectious etiologies, these conditions often lack systemic toxicity but can present with localized warmth, swelling, and stiffness, distinguishing them from mechanical injuries that involve structural damage without immune activation.^[7] Transient synovitis, also known as toxic synovitis, is a common self-limiting inflammatory condition affecting the hip joint in children, typically aged 3 to 8 years, and is more prevalent in males (approximately 70% of cases).^[37] It often follows a viral upper respiratory infection, leading to acute hip pain, limp, and refusal to bear weight in about 40% of affected children; symptoms usually resolve within 1 to 2 weeks with conservative management such as rest and anti-inflammatory medications.^[38] The condition arises from transient immune activation causing synovial effusion without joint destruction, making it a frequent mimic of more serious pathologies but with a benign course.^[39] Juvenile idiopathic arthritis (JIA), a chronic autoimmune disorder, frequently causes limp through oligoarticular involvement of the lower extremities, particularly the knees and hips, in children under 16 years.^[40] The oligoarticular subtype, which accounts for about 50% of JIA cases, presents with morning stiffness lasting over an hour, joint swelling, and an insidious-onset limp due to persistent synovitis; affected children, often young girls, are at increased risk for asymptomatic uveitis, necessitating regular ophthalmologic screening.^[41] Pathologically, T-cell and B-cell dysregulation drives chronic cytokine release, leading to synovial proliferation and potential long-term joint damage if untreated.^[42] Reactive arthritis, triggered by gastrointestinal or genitourinary infections such as those caused by Salmonella or Chlamydia, results in sterile asymmetric oligoarthritis that can produce a limp, especially when lower limb joints like the knees or ankles are involved.^[7] This post-infectious inflammatory response, mediated by molecular mimicry and bacterial antigen persistence, typically emerges 1 to 4 weeks after the inciting infection and affects children and young adults, with symptoms including enthesitis and dactylitis alongside the gait abnormality.^[43] The arthritis is usually self-limited, resolving in 3 to 12 months, but may recur in genetically susceptible individuals with HLA-B27 positivity.^[44] Other inflammatory conditions contributing to limp in youth include acute rheumatic fever, a post-streptococcal autoimmune reaction causing migratory polyarthritis in large joints such as the knees and ankles, leading to painful swelling and transient limp.^[45] This Jones criteria-defined illness, most common in children aged 5 to 15, involves carditis risk and requires prompt antibiotic therapy to prevent rheumatic heart disease.^[46] Psoriatic arthritis, a subtype of JIA occurring in about 5-10% of pediatric arthritis cases, manifests with asymmetric joint involvement, psoriasis-like skin changes, and limp due to enthesopathy or dactylitis in the lower limbs.^[47] These entities underscore the need for targeted evaluation to differentiate inflammatory limp from other etiologies based on chronicity and systemic features.^[48]

Vascular Causes

Vascular causes of limp primarily arise from disruptions in blood supply to the lower extremities, particularly the hip and femoral head, leading to avascular necrosis (AVN), also known as osteonecrosis. This condition involves ischemia of bone tissue due to interrupted blood flow, resulting in cellular death, structural collapse, and subsequent deformity that manifests as pain and an antalgic gait or limp.^[49] The pathophysiology centers on vascular occlusion or insufficiency, which deprives the bone of oxygen and nutrients, triggering a cascade of bone resorption, fragmentation, and potential joint incongruity.^[50] In children, Legg-Calvé-Perthes disease (LCPD) represents the classic idiopathic form of AVN affecting the femoral head, typically occurring between ages 4 and 8 years and predominating in males by about 80%.^[50] The disease progresses through distinct stages: initial necrosis of the epiphysis due to vascular compromise, followed by fragmentation with repair attempts, reossification as new bone forms, and eventual remodeling, though residual deformity may persist and cause limp.^[51] This often presents with insidious hip pain exacerbated by activity, contributing to the limping gait.^[50] Among adults and older children, other vascular etiologies include sickle cell disease crises, where vaso-occlusion by sickled erythrocytes blocks blood flow to the femoral head, leading to AVN in up to 30% of patients by adulthood and resultant hip pain with limp.^[52] Thromboembolic events, such as those associated with deep vein thrombosis or pulmonary embolism, can also precipitate AVN through embolization or hypercoagulability, particularly in the proximal femur, causing acute or subacute ischemic collapse and gait disturbance.^[53] Key risk factors for these vascular disruptions encompass hypercoagulable states, including thrombophilias like Factor V Leiden mutation or antiphospholipid syndrome, which promote clot formation and vascular occlusion.^[54] Prolonged high-dose corticosteroid use is another major contributor, as it induces fat emboli and endothelial damage that impair blood supply to the femoral head.^[55]

Neoplastic Causes

Neoplastic causes of limp arise from tumors that compromise bone structure, leading to pain, instability, or pathologic fractures, particularly in the lower extremities. These lesions disrupt normal bone integrity through proliferative growth, cortical thinning, or marrow infiltration, resulting in antalgic gait or refusal to bear weight. Benign and malignant tumors alike can present this way, though malignant forms often involve more aggressive bone destruction.^[56] Among benign neoplasms, osteoid osteoma is a small, painful tumor typically affecting the cortex of long bones in children and young adults, characterized by a central nidus surrounded by reactive bone. It commonly causes nocturnal pain in the lower limb that is dramatically relieved by nonsteroidal anti-inflammatory drugs (NSAIDs), prompting limping due to localized irritation and inflammation. When located in weight-bearing bones like the femur or tibia, the persistent discomfort exacerbates during activity, leading to an antalgic gait. Unicameral bone cysts, fluid-filled lesions primarily in the proximal humerus or femur of children aged 4-14, weaken the bone cortex and predispose to pathologic fractures, which manifest as acute limp following minimal trauma or even spontaneous events. These cysts rarely cause symptoms until fracture occurs, at which point pain and instability compel weight avoidance.^[57]^[58]^[59] Malignant primary bone tumors, such as Ewing sarcoma and osteosarcoma, frequently present with limp in pediatric patients due to their aggressive local effects. Ewing sarcoma, a small round blue cell tumor arising in the diaphysis of long bones in children and adolescents, often shows an "onion-skin" periosteal reaction on imaging and causes deep, progressive pain leading to limping, sometimes mimicking infection. Osteosarcoma, the most common primary bone malignancy, typically originates in the metaphysis of long bones near the knee in adolescents during growth spurts, producing a soft tissue mass and severe pain that induces limp through bone weakening and pathologic risk. Leukemia, particularly acute lymphoblastic leukemia in children, involves bone marrow infiltration that triggers metaphyseal tenderness and pain, often resulting in refusal to bear weight and a pronounced limp as an early presenting sign.^[60]^[61]^[62]^[63] In adults, metastatic disease from primaries like breast or prostate cancer accounts for most neoplastic limps, with osteolytic or osteoblastic lesions eroding bone integrity and causing pathologic fractures in the femur or pelvis. These metastases lead to sudden or insidious pain with weight-bearing, resulting in limp and mobility impairment, often compounded by hypercalcemia or systemic effects. The pathophysiology across these entities involves tumor-induced osteoclast activation and matrix degradation, which progressively destabilizes bone, amplifies nociception, and alters gait mechanics to offload the affected limb.^[64]^[65]

Neurological Causes

Neurological causes of limp arise from disorders affecting the central or peripheral nervous systems, leading to muscle weakness, spasticity, or sensory deficits that disrupt normal gait mechanics.^[66] These conditions often result in compensatory walking patterns, such as circumduction or high-stepping, to accommodate impaired motor control.^[67] The pathophysiology involves neuromuscular imbalance, where damage to neural pathways impairs coordination between agonist and antagonist muscles during the gait cycle, altering the stance and swing phases.^[66] This imbalance can stem from upper motor neuron lesions causing spasticity or lower motor neuron issues leading to flaccid weakness, ultimately manifesting as an antalgic or ataxic limp to minimize energy expenditure and pain.^[68] In cerebral palsy, particularly spastic diplegia, perinatal brain injury damages the periventricular white matter, resulting in bilateral leg stiffness and hypertonia that produces a scissoring gait, where the legs cross inward during walking, often requiring assistive devices like braces.^[69] This spasticity limits hip abduction and knee extension, contributing to toe-walking and overall limping.^[70] Peripheral neuropathies commonly cause limp through foot drop and steppage gait, characterized by exaggerated hip and knee flexion to clear the toes during the swing phase. Peroneal nerve palsy, often from compression or trauma, weakens ankle dorsiflexors, leading to unilateral foot drop and a slapping sound on heel strike.^[71] In Guillain-Barré syndrome, an autoimmune attack on peripheral nerves produces ascending symmetrical weakness starting in the legs, progressing to difficulty walking or climbing stairs within weeks.^[72]^[73] Spinal cord issues contribute to progressive limp via chronic compression or tethering that affects lower limb innervation. Tethered cord syndrome, resulting from abnormal spinal cord attachment, causes gradual leg weakness and motor deficits as the cord stretches with growth, often accompanied by foot deformities that exacerbate gait instability.^[74]^[75] In adults, lumbar disc herniation can compress the L5 nerve root, inducing radiculopathy with foot drop and a compensatory steppage limp due to impaired dorsiflexion.^[76] Muscular dystrophies, such as limb-girdle types, lead to proximal muscle weakness in the pelvic girdle, resulting in a Trendelenburg gait where the trunk shifts laterally over the affected hip during stance to stabilize balance.^[77] This waddling pattern arises from gluteal weakness and progresses to frequent falls and reliance on upper body support for mobility.^[78]

Diagnosis

History and Physical Examination

The evaluation of a patient presenting with a limp begins with a thorough history to identify potential underlying causes and guide the physical examination. Key elements include the onset of the limp, which may be acute (suggesting trauma or infection) or insidious (indicating inflammatory or neoplastic processes), and its duration, as persistent limps beyond a few days warrant further scrutiny.^[1] A detailed trauma history is essential, inquiring about recent injuries such as falls or sports-related events that could lead to fractures or soft tissue damage.^[1] Associated symptoms should be explored, including fever or rash (potentially signaling infectious or inflammatory etiologies), night pain, weight loss, or systemic complaints like fatigue.^[79] Family history of rheumatologic, bleeding, or neuromuscular disorders provides context for hereditary conditions, while assessing activity level helps differentiate overuse injuries from rest-exacerbated pathologies like malignancy.^[79] The physical examination starts with observation of the patient's gait, ideally from behind and the side, to characterize patterns such as an antalgic limp, where the stance phase on the affected side is shortened to minimize pain.^[1] Palpation follows, systematically assessing the lower extremities, spine, and pelvis for tenderness, swelling, effusion, warmth, or masses that may indicate localized pathology like osteomyelitis or effusion.^[1] Range of motion testing is performed actively and passively for all relevant joints, with specific maneuvers such as the log roll test for the hip to evaluate internal and external rotation without stressing the joint capsule.^[1] Special maneuvers enhance localization during the examination. The Patrick or FABER test (flexion, abduction, external rotation of the hip) elicits pain to suggest intra-articular hip pathology or sacroiliac joint involvement.^[1] The straight leg raise test assesses for sciatica or lumbar radiculopathy by reproducing pain along the sciatic distribution during hip flexion with the knee extended.^[1] Red flags demanding urgent attention include inability or refusal to bear weight, which may signal severe conditions like septic arthritis or fracture, and signs of systemic illness such as high fever or altered mental status.^[79]

Diagnostic Investigations

Laboratory investigations for limp typically begin with basic blood tests to identify signs of infection, inflammation, or systemic disease across all ages. A complete blood count (CBC) may reveal leukocytosis, suggesting an infectious process such as septic arthritis or osteomyelitis, or anemia/thrombocytopenia in neoplastic conditions.^[1] Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are key inflammatory markers; elevated levels (e.g., ESR >40 mm/h or CRP >20 mg/L) support diagnoses like septic arthritis, inflammatory arthritis, or vasculitis. In adults, additional tests such as rheumatoid factor, anti-cyclic citrullinated peptide (anti-CCP) antibodies, or uric acid may evaluate for rheumatoid arthritis or gout, while older adults might require vitamin D levels or parathyroid hormone for metabolic bone disease.^[2] If joint involvement is suspected, synovial fluid analysis via aspiration is the gold standard for confirming septic arthritis or crystal arthropathies, evaluating cell count (>50,000 white blood cells/μL with >75% neutrophils for infection), Gram stain, culture, and crystals.^[1] In children, specific predictors like the Kocher criteria—fever >38.5°C, inability to bear weight, ESR >40 mm/h, white blood cell count >12,000/mm³—help differentiate septic arthritis from transient synovitis, with probabilities of 0.2% (0 predictors), 3% (1), 40% (2), 93% (3), and 99.6% (4).^[80] Imaging studies are essential for structural evaluation and are often the initial confirmatory step. Plain radiographs (X-rays) of the affected limb, pelvis, and hips are recommended first to detect fractures, degenerative changes in osteoarthritis, or bony abnormalities like periosteal reaction in osteomyelitis.^[1] In adults, X-rays may also reveal avascular necrosis or tumors. Ultrasound is valuable for detecting joint effusions and guiding aspiration; while useful in children (effusion depth ≥7 mm raises concern for infection), it cannot reliably distinguish septic from non-septic causes.^[81] Magnetic resonance imaging (MRI) provides detailed soft tissue assessment for avascular necrosis, tumors, infections, or spinal issues, with high sensitivity but considerations for claustrophobia or implants in adults.^[1] Technetium-99m bone scintigraphy is useful for early detection of osteomyelitis or multifocal processes when X-rays are normal (sensitivity 84-100%). For suspected vascular causes like peripheral artery disease, ankle-brachial index (ABI) or Doppler ultrasound may be indicated to assess claudication.^[2] Specialized tests are employed based on clinical suspicion. Electromyography (EMG) and nerve conduction studies (NCS) help evaluate neuropathies or neuromuscular disorders contributing to gait abnormalities.^[1] Biopsy of bone or soft tissue is indicated for confirming neoplastic processes, such as osteosarcoma or metastasis, when imaging suggests a mass. In older adults, dual-energy X-ray absorptiometry (DEXA) scan may assess osteoporosis risk if fragility fractures are suspected.^[79] A stepwise diagnostic algorithm guides escalation: begin with history, physical exam, and X-rays for all patients to rule out fractures or obvious structural issues, followed by laboratory tests if infection, inflammation, or systemic disease is suspected. Further imaging (US, MRI) or aspiration follows based on age and presentation; for example, in pediatric hip pain with effusion and ≥2 Kocher predictors, urgent evaluation for septic arthritis is warranted, while in adults, consider vascular or degenerative etiologies. Age-specific considerations, such as higher infection risk in younger children or osteoarthritis in older adults, tailor investigations.^[1]^[2]

Management

Initial Assessment and Supportive Care

The initial assessment of a patient presenting with a limp begins with triage to identify and rule out life-threatening conditions, such as septic shock from septic arthritis or acute fractures that may require immediate intervention. A thorough history and physical examination should focus on red flags, including acute inability to bear weight, fever, severe localized pain, or systemic symptoms like leukocytosis or elevated inflammatory markers, which may indicate urgent pathologies such as infection or trauma. Pain severity is evaluated using the Visual Analog Scale (VAS), a validated 10-cm line tool where patients mark their pain intensity from 0 (no pain) to 10 (worst possible pain), aiding in quantifying discomfort and guiding initial management.^[82]^[83] Supportive care emphasizes symptom relief and protection of the affected limb through conservative measures. Patients are advised to follow the RICE protocol—rest, ice application for 15-20 minutes every few hours, compression with elastic bandages to reduce swelling, and elevation above heart level—to minimize inflammation and pain in acute presentations.^[1] Analgesics such as acetaminophen (up to 15 mg/kg every 6 hours in children or 500-1000 mg every 6 hours in adults) or nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (10 mg/kg every 6-8 hours in children or 400-600 mg every 6-8 hours in adults) are recommended for pain control, with dosing adjusted based on age, weight, and renal function to avoid complications.^[84] Weight-bearing restrictions, such as partial or non-weight-bearing status, are imposed if fracture or severe joint involvement is suspected, often guided by clinical stability and imaging findings.^[84] Assistive devices play a key role in facilitating mobility while preventing further injury. Crutches or walkers are provided for non-weight-bearing scenarios, such as suspected fractures or acute inflammatory conditions, to offload the affected limb and maintain ambulation.^[1]^[84] For leg length discrepancies contributing to the limp, typically greater than 1-2 cm, shoe lifts or heel inserts are used to equalize limb lengths, reducing compensatory gait abnormalities and associated back pain.^[32]^[31] In pediatric patients, ongoing monitoring through serial examinations is essential to track progression, particularly in ambiguous cases without clear etiology. Follow-up assessments every 24-48 hours initially, or within 7 days for persistent limp, involve repeating gait observation, pain scoring, and joint evaluations to detect worsening symptoms or evolving conditions like transient synovitis resolving into more serious issues. For adults, particularly older individuals, regular follow-up focuses on fall risk assessment and mobility aids to prevent complications like reduced independence.^[85]

Condition-Specific Treatments

For infectious causes of limp, such as septic arthritis, prompt intravenous antibiotics are essential, often starting with empiric coverage targeting Staphylococcus aureus using vancomycin or clindamycin, plus a third-generation cephalosporin like ceftriaxone if gram-negative pathogens (e.g., in neonates, IV drug users, or immunocompromised adults) are suspected, followed by de-escalation based on culture results.^[12] Surgical drainage via arthroscopy or open arthrotomy is typically required to remove purulent material and prevent joint destruction, particularly for hip involvement where delays can lead to avascular necrosis.^[86] Osteomyelitis contributing to limp requires initial intravenous antibiotics for 1-2 weeks followed by oral antibiotics to complete a total course of 4-6 weeks, with surgical debridement if abscess formation occurs.^[9] Mechanical and traumatic etiologies, including fractures (e.g., hip fractures in older adults or toddler's fractures in children), are managed with immobilization using casts or splints to promote healing and restore normal gait, typically for 3-6 weeks depending on the site; surgical fixation may be needed for unstable fractures like those in the hip.^[7] For slipped capital femoral epiphysis (SCFE) in adolescents, surgical in situ fixation with a single percutaneous screw is the standard treatment to stabilize the epiphysis and prevent further slippage, especially in stable cases, while unstable SCFE may require urgent reduction prior to fixation.^[87] Inflammatory conditions causing limp, such as osteoarthritis (common in adults) or transient synovitis (in children), respond to nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen for pain relief and reduced inflammation, often combined with rest and activity modification; symptoms of transient synovitis typically resolve within 1-2 weeks. For chronic inflammatory arthritis like rheumatoid arthritis or juvenile idiopathic arthritis (JIA), treatment includes NSAIDs, intra-articular corticosteroid injections, disease-modifying antirheumatic drugs (DMARDs) like methotrexate, and biologics such as etanercept to achieve remission and preserve joint function.^[35]^[9] Vascular causes like peripheral artery disease (PAD) leading to claudication are managed with supervised exercise programs, smoking cessation, antiplatelet therapy, and medications like cilostazol; revascularization procedures (e.g., angioplasty) may be indicated for severe cases. In children, Legg-Calvé-Perthes disease is treated conservatively with bracing or traction to maintain hip containment and reduce weight-bearing, alongside physical therapy to improve range of motion, aiming to prevent femoral head deformity. Avascular necrosis of the hip, often post-traumatic or steroid-induced in adults, may involve core decompression surgery to relieve intraosseous pressure and promote revascularization, particularly in early stages, with physical therapy to support mobility.^[88]^[89]^[90] Neoplastic causes, such as osteosarcoma (more common in adolescents but possible in adults), presenting with limp due to bone pain, require multimodal therapy including neoadjuvant chemotherapy to shrink the tumor, followed by limb-salvage surgery with wide resection and reconstruction, and adjuvant chemotherapy or radiation depending on the tumor's response and margins.^[91] For neurological etiologies like peripheral neuropathies or stroke-related gait issues in adults causing antalgic gait, physical therapy and orthotic devices such as ankle-foot orthoses are primary to improve biomechanics and strength; in children, conditions like cerebral palsy may require similar interventions, while tethered cord syndrome necessitates surgical release to untether the spinal cord and halt progressive neurological deficits. For Parkinson's disease, levodopa and rehabilitation help manage gait instability.^[7]^[92]^[66] Management of limp often involves multidisciplinary referral to specialists including orthopedics for surgical needs, rheumatology for inflammatory disorders, and neurology for central causes, ensuring coordinated care tailored to the underlying etiology and patient age.^[43]

Epidemiology and Prognosis

Epidemiological Patterns

Limp is a frequent complaint in pediatric primary care and emergency settings, accounting for up to 1.8 cases per 1,000 children annually, though rates vary by age and setting with less than 5% of emergency department consultations involving atraumatic limp.^[93]^[11] In adults, limp is more common among older individuals, driven primarily by osteoarthritis (OA) and trauma-related injuries; for instance, symptomatic hip OA, a key contributor to limping gait, affects approximately 9.2% of adults aged 45 years and older in the United States.^[94] In children, limp peaks in prevalence between ages 3 and 12 years, with a median age of presentation around 4.35 years and a male-to-female ratio of 1.7:1, particularly for hip-related etiologies.^[93] Transient synovitis, one of the most common causes, is often preceded by a recent illness.^[35] Among adults, osteoarthritis of the hip and knee is predominant, and prevalence rising with age to affect over 10% of the general population for hip pain alone.^[95] Obesity exacerbates this trend, with individuals having a BMI greater than 30 facing up to a 7-fold increased odds of knee osteoarthritis compared to those with normal weight.^[96] Globally, limp incidence is higher in developing countries due to elevated rates of infectious causes such as septic arthritis and osteomyelitis, where pediatric osteomyelitis rates can reach 80-196 per 100,000 children—up to 10 times higher than the 9-10 per 100,000 observed in high-income nations.^[97]^[98] In the United States, emergency department data indicate substantial burden, with musculoskeletal complaints including limp contributing to millions of annual visits.^[99]

Prognostic Factors

Prognostic factors for recovery from a limp in children vary significantly depending on the underlying cause, with early intervention generally improving outcomes across etiologies. In cases of transient synovitis, the most common cause of acute limp, symptoms typically resolve completely within 1-2 weeks with conservative management, and approximately 75% of affected children achieve full recovery in this timeframe, though recurrence occurs in up to 25% of cases.^[35] Non-displaced or stable slipped capital femoral epiphysis (SCFE) also carries a favorable prognosis when diagnosed and treated promptly via in situ pinning, with long-term hip function preserved in the majority of patients and a low risk of avascular necrosis (less than 10%).^[100]^[87] Conversely, delayed diagnosis and treatment in septic arthritis of the hip lead to poorer outcomes, including joint destruction and avascular necrosis in up to 56% of late-presenting cases (symptoms exceeding 5 days), highlighting the critical need for urgent intervention to prevent irreversible damage.^[101] Advanced stages of Legg-Calvé-Perthes disease similarly portend a higher risk of femoral head deformity, with good long-term results achieved in only about 50% of untreated cases in children over 4 years old, and overall satisfactory outcomes in 60% across severities.^[102]^[103] Several modifiers influence prognosis beyond the primary etiology. Younger age at onset generally favors better remodeling and recovery, particularly in Perthes disease and SCFE, where children under 8 years exhibit lower rates of residual deformity compared to older patients.^[102] Comorbidities such as obesity can exacerbate outcomes in mechanical causes like SCFE by increasing slip progression risk, while vascular-compromising conditions (e.g., diabetes in rare pediatric cases) may worsen prognosis in ischemic etiologies like Perthes by impairing perfusion.^[100] Patient compliance with therapy, including adherence to non-weight-bearing restrictions and follow-up, is essential for optimizing results, as non-compliance correlates with higher complication rates in surgically managed cases.^[87] Long-term sequelae from hip pathologies in children may include chronic pain due to femoroacetabular impingement or early osteoarthritis, particularly following Perthes or SCFE.^[104] Growth disturbances, such as leg length discrepancy or coxa vara, can occur in pediatric hip disorders like Perthes and SCFE, often necessitating corrective interventions during adolescence.^[105]

Adult Prognosis

In adults, prognosis for limp depends largely on the underlying cause, with osteoarthritis being a leading factor. Symptomatic hip OA progresses in many cases, with approximately 20-30% of patients requiring total hip arthroplasty within 10 years of diagnosis, depending on severity and management.^[106] Early intervention with physical therapy and weight management can improve function and delay surgical needs, though advanced disease often leads to persistent limp and reduced mobility. Traumatic causes like fractures have good recovery rates with appropriate treatment, but chronic conditions such as peripheral artery disease may result in intermittent claudication with variable response to revascularization.^[2]

References

[1]
Antalgic Gait in Adults - StatPearls - NCBI Bookshelf - NIH
It refers to an abnormal pattern of walking secondary to pain that ultimately causes a limp, whereby the stance phase is shortened relative to the swing phase.
[2]
Abnormal Gait: Gait Disorder Types, Causes & Treatments
Gait disorders are an abnormal walking pattern with many possible causes like an injury, sore, an inner ear (balance) issue or nerve damage.
[3]
Evaluation of the acutely limping child - PubMed
Feb 15, 2000 · A limp may be defined as any asymmetric deviation from a normal gait pattern. The differential diagnosis of a limp includes trauma, ...Missing: abnormality | Show results with:abnormality
[4]
Pictorial Review of Paediatric Limp - PMC - PubMed Central
A limp is an abnormal, uneven or laboured gait typically resulting from pain, weakness, or structural deformity involving the hip, lower limb, spine or ...
[5]
Gait: Antalgic - Physiopedia
Antalgic gait is one of the most common forms of altered gait. It refers to an abnormal pattern of walking secondary to pain that ultimately causes a limp.
[6]
Trendelenburg Gait - Physiopedia
A Trendelenburg gait is characterised by a trunk shift over the affected hip during the stance phase and away during the swing phase of gait.Definition/ Description · Epidemiology/ Etiology · Examination
[7]
The Limping Child: A Systematic Approach to Diagnosis - AAFP
Feb 1, 2009 · Abnormal gait can be antalgic or nonantalgic. An antalgic gait, which is characterized by a shortening of the stance phase, is a compensatory ...<|control11|><|separator|>
[8]
Limp - Etymology, Origin & Meaning
"Limp" originates from Old English lemphealt, meaning halting or lame. It means to move with a jerky step or to be flaccid and lacking firmness.
[9]
Evaluating the Limping Child: A Rheumatology Perspective - PMC
The child may have morning stiffness manifested as refusal to walk in the morning or slow awkward gait. Examination of the affected joint(s) reveals swelling ...
[10]
LIMPING IN CHILDREN - PMC - NIH
When it is bilateral, the child increases lumbar lordosis to walk, the gait resembles the duck walk, the trunk is balanced by limiting abduction, and there is ...<|separator|>
[11]
Atraumatic Limping Child, a Challenge for Pediatricians - NIH
Feb 2, 2024 · Limping is defined as a deviation from the normal age-appropriate metric and time parameters of the gait pattern, such as antalgic gait and non ...
[12]
Septic Arthritis - StatPearls - NCBI Bookshelf
Septic arthritis is inflammation of the joints secondary to an infectious etiology such as bacterial, fungal, mycobacterial, viral, or other pathogens.
[13]
Osteomyelitis - StatPearls - NCBI Bookshelf - NIH
May 31, 2023 · Staphylococcus aureus is the most common cause of acute and chronic hematogenous osteomyelitis in adults and children.[1][5] Increasingly ...
[14]
Septic Arthritis: What Is It, Symptoms, Treatment & Causes
Staphylococcus aureus, a type of bacteria, is the most common cause of septic arthritis in both children and adults. Approximately 37% to 56% of septic ...
[15]
Septic arthritis - Symptoms & causes - Mayo Clinic
Septic arthritis can be caused by bacterial, viral or fungal infections. Bacterial infection with Staphylococcus aureus (staph) is the most common cause. Staph ...Overview · Causes · Risk Factors
[16]
Septic Arthritis: Background, Etiology, Pathophysiology
Sep 15, 2025 · The most common pathogens were coagulase-negative Staphylococcus (CoNS), MSSA, and enterococci. The pathogen of Lyme disease, Borrelia ...
[17]
Osteomyelitis - Pediatric - Orthobullets
Osteomyelitis in the pediatric population is most often the result of hematogenous seeding of bacteria to the metaphyseal region of bone.
[18]
Osteomyelitis - Symptoms and causes - Mayo Clinic
Dec 10, 2024 · Causes. Most often, staphylococcus bacteria cause osteomyelitis. These bacteria are germs that live on the skin or in the nose of all people.
[19]
Osteomyelitis | Johns Hopkins Medicine
Osteomyelitis is an inflammation or swelling of bone tissue that is usually the result of an infection. Bone infection may occur for many different reasons and ...
[20]
Lyme Disease - StatPearls - NCBI Bookshelf
Oct 1, 2024 · In the US, Lyme disease is caused by the bacterial spirochete Borrelia burgdorferi (and rarely Borrelia mayonii) and is transmitted by the bite ...Missing: limp | Show results with:limp
[21]
Lyme Disease: Background, Etiology, Pathophysiology
Sep 25, 2025 · Lyme disease is a multisystem illness usually caused by infection with the spirochete Borrelia burgdorferi and the body's immune response to the ...Background · Etiology · Pathophysiology · EpidemiologyMissing: limp | Show results with:limp
[22]
Previously healthy 2-year-old presents with sore throat and limp
Jun 7, 2013 · Reactive arthritis is an inflammatory, sterile arthritis that occurs following certain viral infections such as parvovirus B19 or bacterial ...
[23]
Tuberculous Arthritis of the Ankle - PMC - NIH
The most common symptoms of TB of ankle joint involvement are pain, swelling, limited range of motion, bone tenderness, limping and muscle spasms.
[24]
Tuberculous arthritis - Pathology Outlines
Sep 18, 2024 · Tuberculous arthritis is an extrapulmonary manifestation of tuberculosis infection, presenting as insidious onset of monoarthritis that ...Missing: limp | Show results with:limp
[25]
Complete spontaneous improvement of non-displaced femoral neck ...
Our case is a 46-year-old woman with Garden type II femoral neck fracture, who refused all surgical options and willingly ignored her problem.
[26]
Muscle Contusion (Bruise) - OrthoInfo - AAOS
Contusions cause swelling and pain and can limit joint range of motion near the injury. Torn blood vessels may cause bluish discoloration. The injured muscle ...Missing: limp | Show results with:limp
[27]
The limping child: a systematic approach to diagnosis - PubMed
Feb 1, 2009 · In most children, limping is caused by a mild, self-limiting event, such as a contusion, strain, or sprain. In some cases, however, a limp can ...
[28]
Slipped Capital Femoral Epiphysis - StatPearls - NCBI Bookshelf - NIH
Jul 25, 2023 · SCFE is one of the most common hip pathologies affecting pre-adolescent and adolescent patients, occurring in approximately 10.8/100,000 (Range: ...
[29]
Slipped Capital Femoral Epiphysis: Prevalence, Pathogenesis, and ...
A correlation between rising childhood obesity and increasing incidence of SCFE has been recently reported. Residual abnormal morphology of the proximal femur ...
[30]
Slipped capital femoral epiphysis: a population-based study - PMC
Jul 18, 2017 · The average annual incidence was 4.4/10000 for girls and 5.7/10000 for boys 9–15 years old. Obesity or overweight was found in 56% of the girls ...
[31]
Leg Length Discrepancy—Treatment Indications and Strategies - NIH
The functional characteristic of leg length discrepancy is the shortening limp (1, 2). Gait analyses have shown that leg length discrepancy of >1 cm can result ...
[32]
Lower Limb Length Discrepancy - OrthoInfo - AAOS
Other causes of limb length discrepancy include: Neurologic conditions ... A significant difference can cause a noticeable limp and make it difficult for a child ...
[33]
Osteochondritis dissecans of the knee: Epidemiology, etiology, and ...
Osteochondritis dissecans of the knee is a disease that typically affects skeletally immature patients. Clinically manifested with knee pain, limping, and ...
[34]
Nonspecific Knee Synovitis Caused by Foreign Bodies ... - NIH
Jul 8, 2025 · In this report, we present four such cases of pediatric arthroscopic extraction of a foreign body in the knee joint undetectable by imaging ...
[35]
Transient Synovitis - StatPearls - NCBI Bookshelf - NIH
Transient synovitis is an acute, nonspecific, inflammatory process affecting the joint synovium, particularly in the pediatric patient population.Missing: B19 | Show results with:B19
[36]
The Role of Synovitis in Osteoarthritis pathogenesis - PMC
Most studies have concluded that the presence of synovitis in OA is associated with more severe pain and joint dysfunction.
[37]
Transient Synovitis (Toxic Synovitis): Symptoms, Causes & Treatment
Aug 14, 2025 · Transient synovitis (also known as toxic synovitis) causes hip pain in children that may come on gradually or all of a sudden. Thankfully, it's ...
[38]
Transient Synovitis In Kids | Children's Hospital Colorado
Transient synovitis is an inflammation in the hip joint that causes pain, limp and sometimes refusal to bear weight. This occurs in pre-pubescent children and ...
[39]
Transient synovitis as a cause of painful limps in children - PubMed
Transient synovitis of the hip is one of the most common causes of hip pain and limp in young children. Its cause is still largely unknown.
[40]
Juvenile Idiopathic Arthritis (JIA) Symptoms, Causes & Treatment
What are the symptoms of juvenile idiopathic arthritis? · Eye redness, eye pain and blurred vision · Fatigue or irritability · Fever · Limping · Morning joint ...
[41]
Juvenile idiopathic arthritis - Symptoms and causes - Mayo Clinic
especially first thing in the morning or after a nap.
[42]
Juvenile Arthritis - American College of Rheumatology
Children with JIA may have joint pain and swelling. Signs also include limping, morning stiffness, reluctance to use an arm or leg, reduced activity, and ...
[43]
Limping Child | Pediatrics In Review - AAP Publications
Aug 1, 2024 · Recent illness may suggest infectious or inflammatory causes of limp from the hip, such as transient synovitis or reactive arthritis. In ...
[44]
Post SARS-CoV-2 infection reactive arthritis: a brief report of ... - NIH
Jun 12, 2021 · Limping is a deviation from a normal age-appropriate gait pattern. It is caused by various conditions and is a common cause of referrals to ...
[45]
Rheumatic fever - Symptoms and causes - Mayo Clinic
Dec 2, 2023 · Rheumatic fever is an inflammatory disease that can develop when strep throat or scarlet fever isn't properly treated.Missing: limp | Show results with:limp
[46]
Acute Rheumatic Fever | Doctor - PMM - PMMonline.org
Features suggestive of Acute Rheumatic Fever include: Joint pain and swelling primarily affecting large joints, particularly knees, ankles, wrists and elbows. ...
[47]
For Parents: What is Psoriatic Arthritis?
Psoriatic (sore-er-AT-ic) arthritis or PsA is one of seven sub-types of Juvenile Idiopathic Arthritis that cause inflammation and swelling of the joints.
[48]
What Causes a Child to Limp? - HSS
Sep 17, 2024 · A common reason for pain and limping in early childhood is a condition called “transient synovitis,” also known as “toxic synovitis,” which is temporary.
[49]
Femoral Head Avascular Necrosis - StatPearls - NCBI Bookshelf
Avascular necrosis of the femoral head is a type of osteonecrosis due to disruption of blood supply to the proximal femur.
[50]
Legg-Calve-Perthes Disease - StatPearls - NCBI Bookshelf
Risk factors for Legg-Calve-Perthes disease include: Ten percent familial (there is a delayed bone age by about 2 years). HIV (Up to 5% of HIV patients have ...Continuing Education Activity · Epidemiology · Pathophysiology · Staging
[51]
Legg–Calvé–Perthes disease overview - PMC - PubMed Central
Mar 15, 2022 · Avascularity plays a key role in the etiology of LCPD. Risk factors such as hypertension, increased lipoprotein A, abnormalities in vascular ...
[52]
Complications of SCD: Avascular Necrosis (Death of Bone Tissue)
May 14, 2024 · Avascular necrosis happens when bone tissue dies due to sickled cells blocking blood flow to bones.
[53]
Risk of Venous Thromboembolic Events in Patients with ... - NIH
Dec 6, 2019 · Previous data have shown patients with osteonecrosis of the femoral head (ONFH) have increased lifelong risk of unprovoked venous thromboembolic events (VTE)
[54]
The role of hypercoagulability in the development of osteonecrosis ...
Corticosteroids are one of the most common and best studied predisposing factors of ON. Dosages associated with ON are >2 gr prednisone or its equivalents, ...
[55]
Risk factors and pathogenesis of steroid-induced osteonecrosis of ...
Several risk factors were identified, which included higher dose and prolonged duration of steroid consumption, and underlying disease for which the steroids ...
[56]
Benign Bone Tumors: An Overview of What We Know Today - PMC
Jan 28, 2022 · Nonmalignant bone tumors represent a wide variety of different entities but maintain many common features. They usually affect young patients.
[57]
Osteoid Osteoma in Children Younger than 3 Years of Age - PMC
Sep 9, 2019 · Osteoid osteoma causes pain and limping when localized in the lower extremity. When dealing with preschool children where pain and limping ...
[58]
Unusual localization of osteoid osteoma at the physis of the proximal ...
Mar 8, 2025 · Patients who are diagnosed with osteoid osteoma commonly complain of nocturnal pain that is usually relieved by using nonsteroidal anti- ...
[59]
Interventions for treating simple bone cysts in the long bones of ...
Cysts may lead to repeated pathological fracture (fracture that occurs in an area of bone weakened by a disease process). Occasionally, these fractures may ...
[60]
Clinical and radiographic presentation of pelvic sarcoma in children
Oct 19, 2018 · Eight patients presented with a limp. Five patients had neurologic symptoms including numbness, weakness, or radicular pain (3 Ewing sarcoma ...
[61]
Ewing's Sarcoma - Pathology - Orthobullets
Jun 8, 2025 · limp and ... ~20% rate in those without metastases at initial presentation and >60% rate in those with metastases at initial presentation.
[62]
Pediatric Osteosarcoma: An Updated Review - PMC - PubMed Central
The patients may have limps due to the pain when bearing weight. However, in the early stages, the tumor cannot be palpated and may not even show up on X-ray ...
[63]
Orthopedic manifestation as the presenting symptom of acute ... - NIH
Jun 7, 2020 · Bone and joint pain is particularly frequent in childhood leukemia and can dominate the clinical presentation, during the onset and the course ...
[64]
Osteolytic bone lesions as an initial presenting manifestation of adult ...
Jul 20, 2023 · Bone is a common site of metastases in cancer patients. Prostate and breast cancers are responsible for more than two-thirds of bone metastasis.
[65]
Diseases of Bone - Bone Health and Osteoporosis - NCBI - NIH
Metastatic tumors are often the result of breast or prostate cancer that has spread to the bone (Coleman 2001). These may destroy bone (osteolytic lesion) ...
[66]
Gait Disturbances - StatPearls - NCBI Bookshelf - NIH
Gait disturbances are described as any deviations from normal walking or gait. These deviations occur in the intricate interplay of muscles, joints, and ...Missing: characteristics | Show results with:characteristics
[67]
Gait Abnormalities | Stanford Medicine 25
Seen in patients with foot drop (weakness of foot dorsiflexion), the cause of this gait is due to an attempt to lift the leg high enough during walking so that ...
[68]
Pathophysiology of Gait Disturbance in Neurologic Disorders and ...
Apr 17, 2017 · In patients with neurologic disorders, gait disturbance is a manifestation of a primary problem that alters neural control of ambulation.
[69]
Cerebral Palsy | National Institute of Neurological Disorders and ...
Mar 20, 2025 · People with spastic diplegia/diparesis have muscle stiffness mainly in the legs, but some stiffness in the arms and face is also possible.
[70]
Cerebral palsy - Symptoms and causes - Mayo Clinic
Sep 28, 2023 · Cerebral palsy is a group of conditions that affect movement and posture. It's caused by damage that occurs to the developing brain, most often before birth.
[71]
Foot drop - Symptoms and causes - Mayo Clinic
Jan 15, 2025 · Nerve injury. The most common cause of foot drop is compression of a nerve in the leg that controls the muscles involved in lifting the foot.
[72]
Guillain-Barre syndrome - Symptoms and causes - Mayo Clinic
Jun 7, 2024 · Guillain-Barre (gee-YAH-buh-RAY) syndrome is a condition in which the body's immune system attacks the nerves. It can cause weakness, numbness or paralysis.
[73]
Guillain-Barré Syndrome (GBS): Symptoms & Treatment
Guillain-Barré syndrome is a rare autoimmune condition in which your immune system attacks your peripheral nerves. It causes numbness and muscle weakness.
[74]
Tethered Spinal Cord Syndrome
Jul 19, 2024 · Tethered spinal cord syndrome (TSCS) is a disorder of the nervous system caused by tissue that attaches itself to the spinal cord and limits the movement of ...Missing: limp disc herniation
[75]
Tethered Spinal Cord: What It Is, Symptoms & Treatment
A tethered spinal cord occurs when your spinal cord attaches to your spinal canal. Your spinal cord can stretch and may damage nerves or restrict blood ...Overview · Symptoms And Causes · Diagnosis And TestsMissing: limp disc herniation
[76]
Foot Drop - StatPearls - NCBI Bookshelf
May 1, 2025 · Foot drop is a neuromuscular condition characterized by weakness or paralysis of the dorsiflexor muscles, causing difficulty lifting the forefoot during gait.Missing: limp | Show results with:limp
[77]
Limb Girdle Muscular Dystrophies | PM&R KnowledgeNow
May 30, 2024 · Quality of gait: proximal weakness typically results in waddling (Trendelenburg) gait and toe walking. Gower maneuver may be present ...
[78]
Trendelenburg Gait - StatPearls - NCBI Bookshelf - NIH
Trendelenburg gait is an abnormal gait resulting from a defective hip abductor mechanism. The primary muscle group involved is the gluteal musculature.
[79]
Evaluation of the Acutely Limping Child
### Summary of History and Physical Exam for Acutely Limping Child
[80]
Pediatric Limp Workup: Laboratory Studies, Imaging Studies, Other ...
Apr 11, 2024 · Laboratory testing may be indicated if a serious or systemic cause of limp is suspected. Comprehensive testing is typically not necessary; ...
[81]
The role of ultrasound in differentiating septic arthritis from transient ...
Ultrasound cannot be used safely to distinguish between pediatric septic hip and transient synovitis. It may be a method of value to detect minimal hip effusion ...
[82]
Differentiating between septic arthritis and transient synovitis of the ...
The purposes of this study were to determine the diagnostic value of presenting variables for differentiating between septic arthritis and transient synovitis ...
[83]
Clinical Practice Guidelines : The limping or non-weight bearing child
Most children presenting with a limp do not require investigations · Observing the child's gait may help localise the problem and narrow the differential ...
[84]
Validation of Digital Visual Analog Scale Pain Scoring With a ... - NIH
The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line ...
[85]
Visual Analogue Scale - Physiopedia
The pain VAS is a unidimensional measure of pain intensity, used to record patients' pain progression, or compare pain severity between patients with similar ...
[86]
Pediatric Limp Treatment & Management - Medscape Reference
Apr 11, 2024 · Relief of acute pain · Identification of the cause · Initiation of therapy for the source of the limping · Referral to the appropriate health care ...
[87]
Limping: Evaluation, Diagnosis, and Management in the Pediatric ED
Aug 1, 2006 · If positive, the patient should be admitted, or at least observed for a longer period of time for serial examinations and further management, if ...
[88]
Septic arthritis in children: diagnosis and treatment - PMC - NIH
Staphylococcus aureus and respiratory pathogens are the most common causative agents. Kingella kingae is a regional pathogen that has increasingly been ...
[89]
Acute Bacterial Arthritis in Pediatrics - IDSA
Dec 13, 2023 · High cure rates are achieved with systemic antimicrobials and drainage of infected ... In a study from Finland of children primarily infected by ...
[90]
Slipped Capital Femoral Epiphysis - OrthoInfo - AAOS
Procedures used to treat SCFE include: In situ fixation. This is the procedure used most often for patients with stable or mild SCFE. The doctor makes a small ...
[91]
Perthes Disease - Legg-Calve-Perthes - OrthoInfo - AAOS
The most common surgical procedure for treating Perthes disease is an osteotomy. In this type of procedure, the bone is cut and repositioned to keep the ...
[92]
Avascular necrosis | Children's Hospital of Philadelphia
In some cases, conservative treatments such as rest, activity restriction, physical therapy, and/or pain medication can resolve the pain and swelling. Surgical ...
[93]
Osteosarcoma (bone cancer in children)
About 90 percent of children with osteosarcoma can be treated with limb-sparing (also known as limb-salvage) and reconstructive surgery. CHOP surgeons regularly ...
[94]
Tethered Spinal Cord Syndrome | Children's Hospital of Philadelphia
Tethered cord syndrome treatment typically involves surgery, known as a tethered cord release. The goal of surgery is to untether the spinal cord and prevent ...Missing: limp | Show results with:limp
[95]
The limping child: epidemiology, assessment and outcome - PubMed
The incidence of limp was 1.8 per thousand. The male:female ratio was 1.7:1 and the median age 4.35 years. Limp was mainly right-sided (54%) and painful (80%); ...
[96]
Hip Osteoarthritis: A Primer - PMC - NIH
Jan 3, 2018 · In a prominent US-based population study,13 prevalence of symptomatic hip OA was reported at 9.2% among adults age 45 years and older, with 27% ...
[97]
The epidemiology of transient synovitis in Liverpool, UK - PMC - NIH
Jan 22, 2014 · Two hundred and fifty-nine cases were identified over 5.5 years. The annual incidence was 25.1 (95 % CI 22.1–28.5) per 100,000 0–14 year-olds.Missing: prevalence | Show results with:prevalence
[98]
Chronic hip pain in adults: Current knowledge and future prospective
The prevalence of hip pain in the general population is 10%, and it increases with age.[1] In a published study, 14.3% of adults reported significant hip ...
[99]
Obesity and increased burden of hip and knee joint disease in ...
Dec 20, 2012 · This national study has demonstrated that the odds of arthritis and OA was up to 7 times higher for obese individuals, compared with those classified as ...<|control11|><|separator|>
[100]
Treatment of bone infections in children in low-income countries
The incidence of paediatric osteomyelitis is fundamentally lower in high-income countries with 9–10 per 100,000 inhabitants, whereas in low-income countries ...
[101]
Nationwide epidemiologic study for pediatric osteomyelitis...
According to the previous reports, incidence of osteomyelitis ranges from 0.7 to 196 per 100,000 children, with septic arthritis from 1.1 to 21.2 (Table 3).
[102]
[PDF] National Hospital Ambulatory Medical Care Survey: 2021 ... - CDC
Oct 11, 2023 · NHAMCS used a multistage probability design with samples of primary sampling units, hospitals within primary sampling units, and patient visits ...Missing: limp | Show results with:limp
[103]
Slipped Capital Femoral Epiphysis (SCFE) - Pediatrics - Orthobullets
Feb 3, 2025 · Loder Classification ; Based on ability to bear weight ; Stable. Able to bear weight with or without crutches. Minimal risk of osteonecrosis (<10 ...
[104]
Late-Presenting Septic Arthritis of the Hip in Children
Oct 26, 2023 · However, most authors agree that the delay in treatment beyond five days of symptoms is associated with unsatisfactory outcomes [9-11]. The ...
[105]
Legg-Calvé-Perthes disease: classifications and prognostic factors
> 4 y.o.: 50% of good prognosis without treatment. Grade III ... A low residual percentage and a low perfusion index correlated with a greater deformation ...
[106]
Perthes disease | Radiology Reference Article | Radiopaedia.org
Sep 8, 2025 · Good outcomes are seen up to about 60% of cases16. Prognosis is also influenced by the percentage of femoral head involvement and degree of ...Perthes disease (summary) · Waldenström classification · Catterall classification
[107]
Legg–Calvé–Perthes disease overview
Mar 15, 2022 · The sequelae found in LCPD patients after the age of 40 are minimal, and the long-term prognosis tends to be good in 60% to 80% of the total ...
[108]
Legg-Calve-Perthes Disease - POSNA
The most common treatment is containment which can be achieved non-operatively through casting and bracing or operatively through femoral or pelvic osteotomy.