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Protactinium

Protactinium is a radioactive with 91 and symbol , classified as a dense, silvery-gray metal in the f-block of the periodic table. It has an of 231.036 and occurs naturally in trace amounts in ores, rendering it one of the rarest of all naturally occurring s on . The discovery of protactinium unfolded in the early through the identification of its s. The first , 234Pa, was discovered in 1913 by Kasimir Fajans and Oswald Göhring as a short-lived in the series. In 1917–1918, the more stable 231Pa was independently identified by and , as well as by and John Cranston, from residues. The was named "protactinium" in 1949 by the International Union of Pure and Applied Chemistry (IUPAC), deriving from its role as the progenitor of in the decay chain. Physically, protactinium is a solid at with a of 15.4 g/cm³, a of 1572 °C, and a of 4000 °C. It exhibits metallic luster but tarnishes rapidly in air due to its reactivity. Chemically, it displays oxidation states of +3, +4, and +5, with +5 being the most stable, and it readily reacts with oxygen, , and acids to form compounds such as protactinium oxide (Pa₂O₅). The primary , 231Pa, has a of 32,700 years and decays via alpha emission. Due to its extreme rarity—estimated at only a few parts per trillion in the —and intense , protactinium has no practical applications and is extracted only in microgram quantities from for basic scientific research in and chemistry.

Physical and atomic properties

Appearance and bulk properties

Protactinium metal exhibits a silvery-gray with a bright metallic luster when freshly prepared. It retains this luster for some time upon exposure to air but gradually tarnishes due to the formation of a surface layer. The of protactinium is 15.37 g/cm³ at 20 °C, positioning it among the denser naturally occurring elements and comparable to neighboring actinides like . Protactinium has a of 1,568 °C and a of approximately 4,000 °C, reflecting its high thermal stability typical of . In its pure form, protactinium is ductile and malleable, allowing it to be shaped under mechanical stress, although the presence of impurities can increase its hardness and brittleness. Its is 0.12 J/g·K, indicating relatively low thermal responsiveness compared to lighter metals. The electrical resistivity of protactinium is 1.7 × 10^{-7} Ω·m, consistent with its metallic character, while its thermal conductivity is 47 W/m·K, enabling moderate heat dissipation. Protactinium displays paramagnetic behavior, with a magnetic susceptibility of χ = 1.7 × 10^{-4} cm³/mol, showing no magnetic ordering transitions at standard temperatures. Due to its radioactivity, protactinium experiences self-heating, which can influence its handling and storage.

Atomic structure

Protactinium () is a with 91, positioned in the periodic table as the second member of the series, following ( 90) and preceding ( 92). This placement highlights its role in the f-block, where the 5f orbitals contribute to its electronic structure and chemical behavior. The ground-state electron configuration of protactinium is [Rn] 5f² 6d¹ 7s², reflecting the onset of 5f-orbital filling in the actinide series after the core [Rn] configuration and partial occupation of the 6d and 7s valence shells. Relativistic effects, arising from the high nuclear charge, cause significant contraction of the 6s and 6p orbitals, which poorly shield the nucleus and lead to a gradual stabilization and filling of the 5f orbitals across the actinides, influencing protactinium's atomic properties. The empirical atomic radius of protactinium is 163 pm, indicative of its metallic character within the actinide group. For its ions, the effective ionic radius is 104 pm for Pa⁴⁺ and 92 pm for Pa⁵⁺, both in six-fold coordination, demonstrating the expected decrease in size with higher oxidation states due to greater effective nuclear charge. The successive ionization energies are 568 kJ/mol for the first (removal from 7s), 1,180 kJ/mol for the second, and approximately 2,000 kJ/mol for the third, underscoring the increasing difficulty of electron removal from the contracted orbitals. In natural samples, protactinium occurs exclusively as the isotope ²³¹Pa, with an atomic mass of 231.03588 u, which dominates its measured atomic weight of approximately 231.036 u.

Chemical properties

Reactivity and oxidation states

Protactinium is a highly reactive metal that tarnishes slowly in air upon exposure to oxygen and , though the bulk metal retains its silvery luster for some time before corroding. The powdered form is particularly reactive and ignites spontaneously in air at elevated temperatures. The metal reacts vigorously with water vapor when heated, producing hydrogen gas and protactinium oxide. It also combines with oxygen to form the pentoxide according to the equation: $4\mathrm{Pa} + 5\mathrm{O_2} \rightarrow 2\mathrm{Pa_2O_5} This reaction underscores protactinium's affinity for oxygen, leading to the formation of the stable Pa(V) oxide. In chemical compounds, protactinium exhibits +5 (Pa(V)) as the most stable oxidation state, with +4 (Pa(IV)) also common and accessible under reducing conditions; lower states such as +3 are unstable and tend to disproportionate or oxidize readily. The prevalence of higher oxidation states arises from the electronic configuration of protactinium, where the 5f¹ electron participates minimally in bonding, favoring actinide-like behavior with strong oxidizing tendencies. Due to the large of Pa⁵⁺ (approximately 0.94 Å for 6) combined with its high , protactinium in higher oxidation states readily forms coordination complexes with various ligands, including halides, oxyanions, and chelating agents. These complexes stabilize the metal in and influence its separation and . For instance, in acidic media, Pa(V) coordinates molecules and anionic ligands to mitigate . Protactinium metal demonstrates corrosion resistance toward dilute inorganic acids such as nitric, hydrochloric, and sulfuric, where it reacts slowly or forms protective layers, but it dissolves readily in due to the formation of stable anionic complexes like [PaF₈]³⁻. This selective is exploited in protactinium purification processes.

Thermodynamic properties

The thermodynamic properties of protactinium provide key insights into its and reactivity, particularly in oxidation states relevant to chemistry. The standard for the Pa⁵⁺/Pa⁴⁺ couple is approximately +0.33 in environments, indicating the relative ease of reduction from the pentavalent to tetravalent state under such conditions. For the Pa⁴⁺/Pa couple, the standard is approximately -1.4 , reflecting the strong reducing nature required to obtain metallic protactinium from its tetravalent . Standard enthalpies and Gibbs free energies of formation are available for select protactinium compounds, aiding in the prediction of reaction feasibility. The standard enthalpy of formation for Pa₂O₅ is -1060 kJ/mol, derived from early calorimetric estimates, underscoring the thermodynamic favorability of protactinium oxide formation. For PaCl₅ in the crystalline state, the Gibbs free energy of formation is -846.8 ± 8.8 kJ/mol, calculated from measured enthalpies of solution and auxiliary thermodynamic data. Bulk thermodynamic data for protactinium metal include a of vaporization of 481 kJ/mol, which highlights the significant required to transition the metal to the gas . The of protactinium metal at 298 is approximately 50 J/mol·K, consistent with values for other early actinides and reflecting its . In the Pa-O system, studies reveal the stability of various oxides, with Pa₂O₅ adopting layered s akin to those in Nb₂O₅ and Ta₂O₅. calculations indicate that the ζ-Nb₂O₅-type is the most stable form of Pa₂O₅ at ambient conditions, with a formation of -27.92 eV per , corresponding to enhanced stability due to optimized Pa⁵⁺ coordination in distorted octahedral and pyramidal geometries. Lower oxides like PaO₂ exhibit stability up to higher temperatures, but Pa₂O₅ predominates under oxidizing conditions, influencing the overall equilibria in oxygen-rich environments.

History

Discovery and isolation

The earliest indication of protactinium's existence came in 1900 when examined residues and observed intense , which he attributed to an unknown constituent but could not fully characterize. These observations highlighted the challenges posed by the element's extreme rarity and high , complicating early detection efforts. Protactinium was first identified as a distinct element in by Kasimir Fajans and Oswald Göhring at the University of Karlsruhe in . Working with decay products, they isolated a short-lived (later known as the metastable protactinium-234m) from thorium-234 using the , where imparts to separate daughter products; they named it "brevium" or "uranium-X₂" due to its brief of about 1.17 minutes. This confirmation via radiochemical separation marked a breakthrough, though the element's fleeting nature and intense radiation made further study difficult. In 1917, and John Arnold Cranston at the independently confirmed protactinium as an element by isolating its longer-lived isotope, protactinium-231, from residues through repeated chemical precipitations. Simultaneously, and in achieved the same isolation using similar purification techniques on pitchblende waste, establishing protactinium's position as the parent of in the ; they proposed the name "protactinium" to reflect this relationship. These parallel discoveries underscored the element's scarcity, with only trace amounts available from natural sources. Pure protactinium was first isolated in 1927 by Aristid von Grosse, then working with Hahn in , who obtained about 2 milligrams of protactinium(V) oxide (Pa₂O₅) from 100 tons of residues via fractional from concentrated mineral acids like hydrochloric and . This laborious process, involving hundreds of precipitations to separate protactinium from and other interferents, yielded the first macroscopic sample despite the element's rarity (estimated at one part per 10 million in ores). In 1934, von Grosse further refined the metal by of protactinium pentaiodide (PaI₅), producing elemental protactinium for the first time.

Naming and early research

The element was initially identified in 1913 by Kazimierz Fajans and Oswald Helmuth Göhring, who named the short-lived isotope ^{234m}Pa brevium due to its brief half-life of approximately 1.17 minutes. In 1917–1918, Otto Hahn and Lise Meitner discovered the more stable isotope ^{231}Pa and proposed the name protoactinium, derived from the Greek word protos (meaning "first" or "before") combined with actinium, highlighting its position as the immediate precursor to actinium in the uranium-235 decay series. This nomenclature emphasized the element's radioactive genealogy, distinguishing it from Fajans's earlier term. In 1949, the International Union of Pure and Applied Chemistry (IUPAC) officially adopted the shortened name protactinium, resolving competing designations like brevium and confirming Hahn and Meitner as co-discoverers alongside Fajans and Göhring. This standardization facilitated ongoing research, as the element's scarcity—estimated at about one part per trillion in —had previously hindered systematic study. Early investigations into protactinium's properties began in earnest during the late 1920s and 1930s, led by Aristid von Grosse, who isolated approximately 2 mg of protactinium(V) oxide (Pa_2O_5) in 1927 from uranium residues, marking the first macroscopic preparation. In 1934, von Grosse achieved the isolation of metallic protactinium on a milligram scale using two methods: of protactinium(V) iodide (PaI_5) in a at 1200–1400 °C, and reduction of purified Pa_2O_5 with calcium in a . These efforts not only confirmed protactinium's chemical analogy to but also enabled initial determinations of its atomic weight through synthesis of compounds like K_2PaF_7. Throughout the 1920s to 1940s, researchers focused on protactinium's solution chemistry to develop separation techniques from uranium ores, exploiting its tendency to hydrolyze and form colloids. Von Grosse and others observed that Pa(V) exhibits low solubility in non-complexing acids like HClO_4, HCl, and HNO_3, precipitating readily above pH 5, while stable solutions required highly acidic conditions at tracer levels. Precipitation methods, such as co-precipitation with manganese dioxide or hydrous oxides, proved effective for isolating protactinium from uranium matrices, informing early purification strategies amid growing interest in actinide chemistry during nuclear research initiatives.

Occurrence and production

Natural occurrence

Protactinium is one of the rarest naturally occurring elements, with an estimated abundance in of a few parts per trillion by mass, equivalent to approximately 5 × 10^{-10} % or about 5 parts per trillion. This scarcity arises because protactinium has no stable isotopes, and all natural protactinium consists solely of the radioisotope ^{231}Pa, which has a of 32,760 years and forms as an in the ^{235}U . In equilibrium with in the crust, ^{231}Pa accumulates to trace levels, underscoring its geochemical rarity and dependence on parent s for its presence. The element is primarily associated with uranium- and thorium-bearing minerals, where it occurs at low concentrations due to production. In uranium ores such as pitchblende (), protactinium levels range from 0.1 to 1 ppm, reflecting the equilibrium ratio with ^{235}U content. It is also present in accessory amounts in and thorianite, phosphate and oxide minerals rich in and , respectively, from which ^{231}Pa can be preconcentrated during processing. These mineral associations highlight protactinium's role as a geochemical tracer in actinide-rich deposits, though its total crustal inventory remains minuscule. Beyond Earth, protactinium participates in cosmic nucleosynthesis, where isotopes are synthesized via the rapid neutron-capture (r-) process in core-collapse supernovae, contributing to the production of heavy actinides. Trace quantities of protactinium have been identified in lunar regolith samples returned by Apollo missions, such as those from Apollo 14, confirming its presence in extraterrestrial materials at levels consistent with solar system uranium decay. In aqueous environments like seawater, dissolved protactinium concentrations are extremely low, on the order of 10^{-15} g/L, derived from the ongoing decay of uranium isotopes in ocean waters.

Synthesis and extraction methods

Protactinium-231, the principal isotope, is primarily obtained through extraction from residues generated during processing, where it accumulates as a of -235. These residues, often from minerals like pitchblende, are dissolved in nitric acid-hydrofluoric acid mixtures to solubilize the protactinium, followed by separation techniques such as using anion-exchange resins to isolate Pa(IV) from and other impurities. Solvent extraction methods employing (TBP) in media have also been utilized to selectively extract protactinium from such aqueous solutions, enabling its separation from and based on differences in distribution coefficients. The pure protactinium metal is synthesized by reducing protactinium tetrafluoride (PaF₄) with or calcium vapor at temperatures around 1,400°C under an inert atmosphere to prevent oxidation. This metallothermic process yields metallic protactinium as a distillate or bead, which can then be purified further by . The reaction is typically conducted in a or , with the vaporized to facilitate complete conversion of PaF₄ to the metal. In nuclear reactors, protactinium-233 is produced as an intermediate in the through by , leading to thorium-233, which beta-decays to protactinium-233 with a of 27 days; this protactinium subsequently decays to , supporting the breeding of . This reactor-based allows for the isolation of protactinium-233 from irradiated thorium targets via chemical separation, though it is often allowed to decay in situ for generation. A notable large-scale production occurred in 1961 by the , which purified approximately 125 g of protactinium by a 12-stage from 60 tons of , followed by adsorption onto silica columns and for further refinement. Overall, extraction from natural sources has yielded only about 125 g of protactinium historically, with achievable purities reaching up to 99.5%.

Isotopes

Principal isotopes

Protactinium has no isotopes, with all 30 known radioisotopes being radioactive and spanning mass numbers from ²¹⁰Pa to ²³⁹Pa. These isotopes primarily decay via alpha (α) emission or beta-minus (β⁻) decay, reflecting the element's position in the series. The principal isotopes are those with the longest half-lives or significant natural or synthetic relevance, including ²³¹Pa, ²³³Pa, and ²³⁴Pa (with its ). The most stable isotope, ²³¹Pa, has a half-life of 32,760 years and undergoes α decay to ²²⁷Ac. It occurs naturally as part of the ²³⁵U decay chain (actinium series), constituting nearly all terrestrial protactinium. Another key isotope, ²³³Pa, has a half-life of 26.97 days and decays via β⁻ emission to ²³³U. It is produced synthetically in thorium-based nuclear reactors through neutron capture on ²³²Th, followed by β⁻ decay of ²³³Th. The ²³⁴Pa exists in two forms: the with a of 6.70 hours and the metastable ²³⁴mPa with a of 1.17 minutes. Both primarily undergo β⁻ to ²³⁴U, with the first decaying via isomeric transition (IT) to the ; ²³⁴Pa occurs naturally in trace amounts in the ²³⁸U (uranium series). Among neutron-deficient isotopes, ²¹⁰Pa represents a recent in 2025, with a of approximately 6 ms and α . It was synthesized via multinucleon transfer reactions and marks the current limit of known protactinium isotopes on the proton-rich side.
IsotopeHalf-lifeDecay mode(s)Principal decay productOccurrence/Production
²³¹Pa32,760 yearsα²²⁷AcNatural (²³⁵U chain)
²³³Pa26.97 daysβ⁻²³³USynthetic (thorium reactors)
²³⁴Pa (ground)6.70 hoursβ⁻, EC²³⁴U, ²³⁴ThNatural (²³⁸U chain)
²³⁴mPa1.17 minutesIT, β⁻²³⁴Pa, ²³⁴UNatural (²³⁸U chain)
²¹⁰Pa~6 msα(not specified)Synthetic (2025 discovery)

Nuclear fission and decay

Protactinium isotopes undergo nuclear decay primarily through alpha and beta processes, with fission occurring mainly via induced neutron interactions rather than spontaneous events. Spontaneous fission is exceedingly rare for protactinium isotopes, with branching ratios below 10^{-10} for the principal isotope ^{231}Pa, making it negligible compared to alpha decay. Induced fission of ^{231}Pa requires neutron energies above approximately 1 MeV, as established by early measurements showing no significant cross section below this threshold. In the , protactinium plays a critical role through the intermediate ^{233}, formed via on ^{232}. The sequence proceeds as ^{232}\mathrm{Th} + n \to ^{233}\mathrm{Th} \xrightarrow{\beta^-} ^{233}\mathrm{Pa} \xrightarrow{\beta^-} ^{233}\mathrm{U}, where ^{233}Th has a of 22 minutes and ^{233}Pa decays over 27 days. The accumulation of ^{233}Pa impacts neutron economy due to its substantial thermal capture cross section of 38.3 ± 1.8 barns, which competes with the desired of fissile ^{233}U and reduces in reactors. While ^{233}Pa is theoretically fissionable by thermal neutrons, the direct cross section is extremely low at about 2.5 μbarns, rendering it practically non-fissile in thermal spectra; fission becomes viable only with fast neutrons above several keV, where cross sections rise to hundreds of millibarns. The of ^{231}Pa contributes to in nuclear materials, generating approximately 0.0014 W/g based on its 32,760-year and ~5 MeV alpha energy release. This low but persistent output arises from the within the series and must be accounted for in long-term storage of spent fuel or containing protactinium. Key isotopes like ^{231}Pa ( 32,760 years) and ^{233}Pa (27 days) illustrate the range of decay timescales influencing dynamics. Recent research has advanced understanding of protactinium's properties through of neutron-deficient via multinucleon reactions, which probe effects and barriers in light actinides. In 2025, the neutron-deficient isotope ^{210}Pa was and identified using gas-filled recoil ion separation, providing insights into chains and potential paths near deformed .

Chemical compounds

Oxides and chalcogenides

Protactinium(V) oxide, Pa₂O₅, is the principal and most stable oxide of protactinium, typically appearing as a white solid. It can be prepared by calcining various protactinium compounds, such as the hydrated oxide or other precursors, in air or oxygen at temperatures above 500 °C, resulting in a dense material with a density of approximately 10.96 g/cm³. Structural studies indicate that Pa₂O₅ adopts either a cubic fluorite-type structure (space group Fm3m, lattice parameter ~5.455 Å) or an orthorhombic form (lattice parameters ~6.92 Å × 4.02 Å × 4.18 Å), depending on preparation conditions, with protactinium in the +5 oxidation state coordinated by oxygen atoms in distorted octahedral environments. PaO₂, the dioxide, is obtained by reducing Pa₂O₅ with gas at high temperatures, such as 1,550 °C, yielding a black solid that adopts a cubic ( Fm3m, parameter 5.505 Å). In this compound, protactinium is in the +4 , forming a face-centered cubic similar to other dioxides like ThO₂, with Pa atoms eight-coordinated by oxygen. PaO₂ is stable under inert atmospheres but oxidizes in air to higher oxides. Other oxides include the mixed-valence Pa₃O₇, which forms under controlled oxidation conditions of lower oxides and exhibits intermediate stability between PaO₂ and Pa₂O₅, though detailed structural data remain limited. , a monoxide, is less stable and prepared under strongly reducing conditions, potentially adopting a rock-salt structure akin to other early monoxides, but it readily disproportionates in air. of protactinium species in aqueous media leads to the formation of hydrated oxides, Pa₂O₅·nH₂O (where n varies), which are amorphous or poorly crystalline precipitates used in separation processes and dehydrate upon heating to yield anhydrous Pa₂O₅. Protactinium chalcogenides, such as , PaSe, and , are prepared by direct combination of protactinium metal or oxides with the respective elements at high temperatures under inert or vacuum conditions. appears as a black solid with a rock-salt structure (NaCl-type), where Pa is in the +4 and coordinated octahedrally by ions, exhibiting semiconducting properties. PaSe and follow similar synthetic routes, forming dark, layered or cubic structures with increasing chalcogen size, though their stability decreases down the group, and detailed crystallographic data are sparse due to handling challenges from . Higher chalcogenides like β-PaS₂ and γ-PaSe₂ have also been synthesized, showing polymeric or layered motifs. A recent advancement in 2025 involved the of (PaO)₂(SO₄)₃(H₂O)₂ from a of protactinium precipitates, , and 3 M under hydrothermal conditions (200 °C for 7 days), revealing a monoclinic structure ( C2/c, parameters a = 22.2345 , b = 6.6587 , c = 7.9279 , β = 96.894°) with polymeric chains linked by Pa–O bonds. In this compound, Pa(V) centers exhibit eight-coordinate, distorted bicapped trigonal prismatic geometry, bonded to five monodentate ligands, two molecules, and one group, with Pa–O distances ranging from 2.004(3) to 2.451(4) , providing insights into protactinium's coordination chemistry in sulfate media.

Halides

Protactinium forms several halides in both the +4 and +5 oxidation states, with the pentahalides generally more volatile and useful for separation processes due to their ability to or volatilize at relatively low temperatures. These compounds are typically synthesized under conditions to prevent , and their structures reflect the large size and high coordination numbers typical of elements. Fluorides are the most stable and well-studied, while heavier halides are less stable and more prone to . PaF₄ is a white solid prepared by reacting protactinium(IV) hydroxide, Pa(OH)₄, with (HF). It serves as a key intermediate for the reduction to protactinium metal using calcium or other reductants at elevated temperatures. The compound adopts a body-centered tetragonal , consistent with other tetrafluorides like ThF₄ and UF₄, where Pa is eight-coordinate with fluorine ligands. PaF₅, the protactinium pentafluoride, is a volatile white solid, making it valuable for purification and separation via volatilization methods. It is synthesized by fluorination of PaF₄ with gas (F₂) at 700°C in a apparatus to avoid formation of oxofluorides. In the gas phase, PaF₅ exists as discrete trigonal bipyramidal monomers with D_{3h} , though the solid state features polymeric chains with bridging fluorides and nine-coordinate Pa centers. The chlorides include PaCl₄ and PaCl₅. PaCl₄ is a brown solid obtained by reduction of PaCl₅ at 800°C or by chlorination of PaO₂ with (CCl₄). It has a tetragonal structure similar to ThCl₄, with Pa in a coordination of eight chlorides. PaCl₅ is a hygroscopic, pale yellow solid prepared by oxidation of PaCl₄ with gas (Cl₂) at 400–500°C or by reacting Pa₂O₅ with (COCl₂). It is used in volatility-based separations, though it is less stable than the fluoride analogue. For the bromides and iodides, the pentahalides PaBr₅ and PaI₅ are less stable than their lighter counterparts and tend to decompose to the tetrahalides upon heating or exposure to . PaBr₅ is a red-brown solid synthesized by bromination of PaO₂ with , while PaI₅ is dark and even more unstable, prepared similarly but requiring inert conditions. PaI₄, the tetraiodide, is obtained by direct reaction of protactinium metal with iodine (I₂) at 500°C, yielding a black solid that is sparingly soluble in solvents. These heavier halides exhibit lower due to weaker Pa–X bonds, with PaI₄ adopting a layered analogous to PaCl₄. Protactinium halides are highly reactive toward moisture and undergo to form oxohalides, such as PaOCl₃ from PaCl₅ in humid air or dilute HCl solutions. This reactivity necessitates handling and underscores their utility in processes, where fluorides like PaF₅ enable selective volatilization from oxide matrices.

Other inorganic compounds

Protactinium(V) nitrate, Pa(NO₃)₅·nH₂O, is a hydrated that exhibits good in and dilute acids, facilitating its use in radiochemical separations of actinides. It is typically prepared by dissolving protactinium in , yielding solutions stable for short periods under controlled conditions. However, the compound hydrolyzes slowly in 6 N HNO₃ at concentrations of 10⁻³ to 10⁻⁴ M, though it remains stable for up to 24 hours at lower concentrations; yields Pa₂O₅. Protactinium(V) sulfate, Pa₂(SO₄)₅, appears as a white precipitate when formed from acidic solutions and is valued for its stability in sulfate media during extraction processes. Prepared by digesting protactinium pentoxide in concentrated , it dissolves readily in hot , achieving solubilities of 17 mg/mL in 7.7 N (stable for over a year) and 36 mg/mL in 3 N (stable for six months). The protactinium , PaH₃, is a non-stoichiometric black powder obtained by exposing protactinium metal to gas at approximately 300°C. This compound is reactive and decomposes at elevated temperatures, sharing an isostructural relationship with trihydride; theoretical investigations indicate a cubic with potential superconducting behavior under . compounds such as PaAl₄ and PaBe₁₃ are synthesized via arc melting of the elements or beryllothermic reduction of protactinium oxide, respectively, and exhibit metallic properties suitable for studies of alloy behavior. PaBe₁₃ adopts a cubic NaZn₁₃-type structure. These materials are explored for their magnetic and electronic characteristics due to protactinium's limited availability. Protactinium (PaC) and (PaN) represent inorganic compounds with high melting points, prepared on scales through carbothermal of Pa₂O₅ for PaC and direct reaction of protactinium with at elevated temperatures for PaN. PaC is isostructural with UC and demonstrates chemical inertness, while PaN offers thermal stability, both contributing to understanding protactinium's behavior in extreme environments despite synthetic challenges.

Organometallic compounds

Organometallic chemistry of protactinium is limited primarily due to the element's intense and scarcity, which restrict experimental studies to small-scale syntheses in specialized facilities. These constraints have focused research on key es that probe the involvement of 5f orbitals in metal-ligand , revealing protactinium's hybrid actinide-transition metal character. A prominent example is tetrakis(cyclopentadienyl)protactinium(IV), Pa(C₅H₅)₄, a tetrahedral featuring four η⁵-cyclopentadienyl ligands coordinated to the Pa(IV) center. This air-sensitive compound is synthesized by reacting protactinium(IV) chloride, PaCl₄, with , NaC₅H₅, in a solution under inert conditions. The exhibits stability typical of early metallocenes, with the cyclopentadienyl rings providing strong π-donation to the metal, influencing the 5f orbital participation in . Another notable organometallic species is bis(cyclooctatetraenyl)protactinium, Pa(C₈H₈)₂, also known as protactinocene, which adopts a sandwich structure analogous to . This golden-yellow Pa(IV) complex is prepared by reducing protactinium(V) chloride with metal in the presence of , followed by extraction and purification under anaerobic conditions. Computational studies highlight its electronic structure, where relativistic effects stabilize the 5f¹ configuration, leading to significant f-orbital contributions to the Pa-C bonding and optical properties. Protactinium also forms coordination complexes in +4 and +5 oxidation states with β-diketonate ligands, such as tetrakis(2,2,6,6-tetramethylheptane-3,5-dionato)protactinium(IV), Pa(thd)₄, which features direct Pa-O bonds but incorporates frameworks for volatility and solubility. These compounds are typically accessed via solvent extraction or ligand exchange reactions from Pa(IV) or Pa(V) salts in media. Such β-diketonates aid in understanding protactinium's coordination preferences, though their organometallic character is more coordination-based than covalent M-C bonding.

Applications and research

Scientific uses

Protactinium's extreme rarity severely constrains its scientific applications, with only approximately 125 grams of pure protactinium-231 ever isolated worldwide through extensive processing of nuclear waste material. This limited availability confines research to microgram- or milligram-scale experiments, often involving isotopes produced via irradiation of in reactors. Basic investigations into its physical properties have revealed that protactinium metal is paramagnetic, exhibiting no magnetic phase transitions across measured temperatures, with a consistent with localized 5f electrons. Additionally, protactinium becomes superconducting at temperatures below 1.4 K, with an upper critical magnetic field of about 120 , providing insights into actinide electron-phonon interactions. During the in the early 1940s, protactinium was isolated from neutron-irradiated at the , to evaluate the thorium-uranium fuel cycle as an alternative to uranium-based . Researchers, including and John W. Gofman, determined that protactinium-233 acts as a absorber, complicating the production of fissile and informing process monitoring and optimization strategies for potential reactor operations. In , protactinium-233, an intermediate in the , has been employed in cross-section measurements to characterize interactions for advanced designs. Experiments using monoenergetic beams have quantified its probability across energy ranges from to fast neutrons, revealing a capture cross-section of approximately 38 barns for neutrons, which aids in modeling economy and risks. Protactinium-231 serves as a geochemical tracer in uranium-series methods, leveraging the ²³¹Pa/²³⁵U activity ratio to reconstruct past circulation patterns and conditions. In , its conservative behavior in —due to rapid scavenging onto particles—enables quantification of deep-water rates over millennial timescales, while in , excess ²³¹Pa in marine sediments indicates changes in during glacial-interglacial transitions. Additionally, ²³¹Pa is used in uranium-series to date geological events, such as speleothems and corals, by measuring ²³¹Pa/²³⁵U ratios, complementing ²³⁰Th for timescales up to 300,000 years. This application exploits protactinium's of 32,760 years, providing a complementary timescale to thorium-230 for sediments older than 100,000 years.

Recent developments

In 2025, researchers at the Institute of Modern Physics of the synthesized the neutron-deficient protactinium-210 (²¹⁰Pa) using the fusion-evaporation ¹⁷⁵Lu(⁴⁰Ca, 5n) at the CAFE2 facility. This , the most proton-rich form of protactinium observed to date, exhibits an half-life of 6.0⁺¹·⁵₋₁·₁ ms and an alpha-particle energy of 8284(15) keV, providing new insights into alpha-decay systematics near the proton drip line and advancing studies of heavy nuclei stability. A significant advancement in protactinium chemistry occurred in 2025 with the crystallization and structural determination of the Pa(V) complex (PaO)₂(SO₄)₃(H₂O)₂, achieved through a synthetic approach involving boric and sulfuric acids. Single-crystal X-ray diffraction revealed a monoclinic structure (space group C2/c) where each Pa atom is eight-coordinate in a distorted bicapped trigonal prismatic geometry, featuring two bridging oxo ligands (Pa–O distances of 2.004(3) Å and 2.143(3) Å), five monodentate sulfates, and one water molecule. This non-linear Pa–O–Pa bridge (angle 147.5°) contrasts with typical actinyl dioxo motifs and highlights protactinium's unique coordination preferences among early actinides. In , a 2024 emphasized 's role as a geochemical analog for transuranic elements like and , aiding understanding of their microbial-mediated mobility and speciation in subsurface environments contaminated by nuclear activities. Studies underscore Pa's similar behaviors on minerals and reductive by , informing models of transport in natural systems. Recent theoretical investigations (2022–2024) have employed relativistic (DFT) and to probe protactinium bonding, particularly in mono-oxo Pa(V) species. These computations reveal that the Pa=O bond is weaker and longer than previously estimated (Pa–O ≈ 1.78 Å), influenced by relativistic effects on 5f orbital participation, challenging assumptions about covalency in aqueous and complexed forms. Research proposes the use of ²³¹Pa in specialized thorium-based fuels as a burnable absorber to control reactivity, as explored in coupled-channel optical model analyses up to 20 MeV energies.

Safety and handling

Health hazards

Protactinium is highly toxic primarily due to its radiological properties as an emitter, which can cause severe tissue damage if inhaled or ingested, as s deposit their energy locally within biological tissues. The principal isotope, ²³¹Pa, has a of 0.048 /g, leading to significant internal upon absorption. In addition to its radiological toxicity, protactinium exhibits chemical toxicity akin to other actinides, accumulating preferentially in the skeleton (approximately 40%), liver (15%), and kidneys (2-12%) following internal exposure, where it can induce radiation necrosis and long-term organ damage. The biological half-life in the skeleton is about 50 years, prolonging exposure and increasing the risk of chronic effects such as chromosomal damage and genotoxicity. Protactinium is carcinogenic due to from internal deposition, with no established safe exposure limit; lifetime cancer mortality risks are estimated at 2.5 × 10⁻⁷ per pCi inhaled and 6.0 × 10⁻¹⁰ per pCi ingested for ²³¹Pa. Safe handling of protactinium requires containment in glove boxes to prevent or , and ²³¹Pa samples necessitate specialized long-term storage.

Environmental precautions

Protactinium exhibits limited environmental mobility due to its low solubility and strong sorption tendencies in typical groundwater and soil conditions. In near-field repository environments at pH 11–12, the apparent solubility limit of protactinium is approximately 10^{-10} M, while in far-field settings at neutral pH, solubility remains comparably low under oxidizing conditions relevant to Pa(V) species. High distribution coefficients (R_D) ranging from 10^2 to 10^6 mL g^{-1} on solid phases such as cement, clay minerals, and iron oxides further restrict migration, as protactinium rapidly adsorbs onto these materials, forming stable complexes that limit dissolution and transport in aqueous systems. The long half-life of its primary isotope, ^{231}Pa (32,760 years), underscores the potential for persistent contamination if releases occur, though natural traces associated with uranium ores in mining sites highlight the need for ongoing hydrogeochemical monitoring to track low-level dispersion. As a fission product and neutron capture byproduct in nuclear fuel cycles, protactinium is classified as high-level radioactive waste (HLW) under international standards, necessitating immobilization techniques to ensure long-term isolation from the biosphere. Vitrification, where protactinium is incorporated into borosilicate glass matrices, is a primary method for stabilization, producing durable forms resistant to leaching under repository conditions; alternatively, deep geological disposal in stable formations like salt or granite repositories provides multi-barrier containment against groundwater intrusion. These approaches align with requirements for HLW management, preventing release of actinides like protactinium into surface or subsurface environments. Regulatory frameworks emphasize stringent controls on protactinium emissions to safeguard ecosystems, with the (IAEA) establishing effluent discharge limits for actinides based on dose constraints to minimize radiological impact on aquatic and terrestrial systems. Monitoring protocols at and processing sites, where protactinium occurs as a , involve routine sampling of leachates and to detect trace levels and ensure compliance with these thresholds. Safe handling protocols for protactinium prioritize containment to avert environmental release, mandating use within sealed glove boxes or inert-atmosphere enclosures that maintain and filtration to capture aerosols and prevent dispersion. Decontamination of surfaces or equipment exposed to protactinium relies on chelating agents like diethylenetriaminepentaacetic acid (DTPA), which forms soluble complexes with actinides to facilitate removal and neutralization, often combined with acidic washes in controlled settings. Recent biogeochemical investigations have reinforced that protactinium's strong to sediments, particularly biogenic and authigenic particles in aquatic environments, substantially reduces its and potential for trophic transfer, thereby mitigating ecological risks in contaminated watersheds.

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