A rotator cuff tear is an injury to the group of four muscles and their tendons—supraspinatus, infraspinatus, teres minor, and subscapularis—that form a cuff around the shoulder joint, stabilizing the humerus in the glenoid socket and enabling arm rotation and elevation.[1][2] This tear can be partial or complete, involving detachment of the tendon from the bone, and is one of the most frequent causes of shoulder pain and impaired function in adults, with nearly 2 million annual doctor visits in the United States.[1]Rotator cuff tears arise from two primary mechanisms: acute injury, such as a fall or sudden forceful lifting that overwhelms the tendon, and degenerative changes due to repetitive overhead motions, aging, or reduced blood supply to the tendons, which thins and weakens them over time.[1][2] The risk escalates significantly after age 40, with prevalence highest in individuals over 60, and is elevated in occupations involving heavy lifting or repetitive arm use, such as carpentry or painting, as well as in athletes in sports like baseball or tennis.[1][2]Symptoms typically include a persistent dull ache in the shoulder, often radiating down the arm, that intensifies at night or with overhead activities, accompanied by weakness, limited range of motion, and sometimes a cracking sensation during movement.[1][2] Acute tears may present with sudden, severe pain and immediate loss of strength, while chronic degenerative tears can be asymptomatic initially but progress to disability if untreated, potentially leading to permanent loss of motion or arthritis in the joint.[1][2]Diagnosis involves a thorough medical history, physical examination to assess strength and range of motion, and imaging such as X-rays to rule out bone issues, ultrasound, or MRI to visualize the tear's size and location.[1]Treatment is often conservative for partial tears or older patients, incorporating rest, nonsteroidal anti-inflammatory drugs, physical therapy to restore strength and flexibility, and corticosteroid injections, which succeed in 80-85% of cases.[1] For full-thickness tears causing ongoing symptoms, surgical options like arthroscopic repair to reattach the tendon are common, followed by rehabilitation.[1][2] Prevention emphasizes maintaining shoulder strength through targeted exercises and avoiding excessive repetitive overhead stress.[1]
Anatomy and Pathophysiology
Rotator Cuff Components
The rotator cuff is composed of four primary muscles—supraspinatus, infraspinatus, teres minor, and subscapularis—whose tendons converge to form a musculotendinous cuff that envelops the anterior, superior, and posterior aspects of the humeral head.[3] These tendons blend seamlessly with the glenohumeral joint capsule, providing structural integrity to the shoulder joint.[3]The supraspinatus originates from the supraspinous fossa of the scapula and inserts onto the superior facet of the greater tuberosity of the humerus.[3] The infraspinatus arises from the infraspinous fossa of the scapula and attaches to the middle facet of the greater tuberosity.[3] The teres minor originates along the lateral border of the scapula, inferior to the glenoid fossa, and inserts onto the inferior facet of the greater tuberosity.[3] In contrast, the subscapularis originates from the subscapular fossa of the anterior scapula and inserts onto the lesser tuberosity of the humerus.[3]The rotator cuff structures lie inferior to the coracoacromial arch, formed by the coracoid process, acromion, and coracoacromial ligament, which creates an osseoligamentous roof over the humeral head.[3] Adjacent to this, the subacromial bursa provides a lubricating interface between the cuff tendons and the overlying arch.[3]Blood supply to the rotator cuff primarily derives from the suprascapular artery for the supraspinatus and infraspinatus, the subscapular artery for the subscapularis, and the posterior humeral circumflex artery for the teres minor.[3] Innervation is provided by the suprascapular nerve (C5-C6) to the supraspinatus and infraspinatus, the axillary nerve (C5-C6) to the teres minor, and the upper and lower subscapular nerves (C5-C7) to the subscapularis.[3]Histologically, the rotator cuff tendons consist predominantly of type I collagen fibers, which comprise over 95% of the total collagen content and are organized in parallel bundles to facilitate force transmission.[4] These fibers are embedded in an extracellular matrix with proteoglycans and water, while tenocytes—elongated, spindle-shaped fibroblast-like cells—reside between the fibers and maintain tendon homeostasis.[5] Through their coordinated action, the rotator cuff muscles contribute to glenohumeral joint stability by compressing the humeral head against the glenoid fossa.[6]
Normal Biomechanics
The rotator cuff muscles play a crucial role in maintaining glenohumeral joint stability by depressing the humeral head and centering it within the glenoid fossa during arm elevation, thereby preventing superior migration of the humerus against the acromion.[7] This dynamic stabilization is achieved through the coordinated contraction of the supraspinatus, infraspinatus, teres minor, and subscapularis muscles, which form a musculotendinous cuff that compresses the humeral head into the shallow glenoid socket.[3] In normal function, these muscles generate compressive forces that enhance joint congruence and resist translational forces, ensuring smooth arthrokinematics throughout the shoulder's wide range of motion.[7]Each rotator cuff muscle contributes specific actions to shoulderkinematics. The supraspinatus initiates abduction, particularly effective in the initial 20 to 30 degrees, where it works to elevate the arm without significant scapulothoracic contribution. The infraspinatus and teres minor facilitate external rotation, allowing the humerus to rotate laterally relative to the scapula, while the subscapularis enables internal rotation by drawing the humerus medially.[3] These actions are not isolated but interdependent, providing balanced torque to maintain humeral head position during multiplanar movements.[7]The rotator cuff interacts closely with the deltoid muscle to create balanced force couples, particularly in the coronal plane for abduction and in the transverse plane for rotation. During abduction, the supraspinatus counters the superior pull of the deltoid by depressing the humeral head, forming an inferior force couple that stabilizes the joint and allows efficient elevation up to 90 degrees or more.[7] Similarly, in rotation, the anterior (subscapularis) and posterior (infraspinatus and teres minor) cuff muscles balance the deltoid's rotational components.[3] Additionally, the rotator cuff contributes to glenohumeral stability through proprioceptive feedback from muscle spindles and mechanoreceptors, which facilitate anticipatory muscle activation to fine-tune jointposition and movement.[7]
Tear Pathophysiology
Rotator cuff tears often arise from degenerative processes that compromise tendon integrity, particularly in the supraspinatus tendon. A key feature is hypovascularity in the "critical zone," located approximately 12-15 mm proximal to the tendon insertion on the greater tuberosity, where reduced blood supply impairs nutrient delivery and waste removal, predisposing the tissue to degeneration.[8] This hypovascular region contributes to fibrocartilaginous metaplasia, in which tendon fibroblasts transform into chondrocyte-like cells, leading to altered extracellular matrix composition with increased glycosaminoglycans and disorganized collagen fibers, further weakening the tendon structure.[9] These changes reflect a gradual breakdown rather than acute failure, with histologic evidence showing myxoid degeneration, collagen disorganization, and vascular ingrowth attempts in affected areas.[10]The pathophysiology aligns with the continuum model of tendon pathology, which delineates three progressive stages: reactive tendinopathy, dysrepair, and degenerative tendinopathy. In the reactive stage, mechanical overload triggers cell proliferation and matrix adaptation without structural failure, marked by increased proteoglycan content and mild inflammation.[11] Progression to dysrepair involves failed healing with neovascularization, disorganized collagen, and heightened enzymatic degradation, while the degenerative stage features cell loss, fatty accumulation, and irreversible matrix disruption, culminating in partial or full-thickness tears.[12] This model underscores how rotator cuff tendons transition from adaptive responses to chronic breakdown, influenced by repetitive stress and age-related factors.Tears are classified as partial-thickness, involving only the articular or bursal side without complete disruption, or full-thickness, extending through the entire tendon depth and allowing communication with the subacromial space.[13] In chronic full-thickness tears, the torn tendon edges retract medially due to muscle imbalance and elasticity loss, often accompanied by supraspinatus muscle atrophy and fatty infiltration, where adipocytes replace myofibers, reducing contractile force and complicating repair.[14] Partial tears may remain stable or propagate to full-thickness over time, with retraction less pronounced but still contributing to biomechanical instability.An inflammatory cascade exacerbates tissue damage, involving cytokines such as interleukin-1β (IL-1β), which upregulates matrix metalloproteinases (MMPs) like MMP-1 and MMP-13, promoting collagen breakdown and extracellular matrix remodeling.[15] These MMPs, alongside tumor necrosis factor-α and other proinflammatory mediators, create a feedback loop that sustains degeneration, particularly in the hypovascular zones where repair signals are diminished.[16]Healing of rotator cuff tears is limited by intrinsic repair mechanisms due to avascular regions that hinder cell migration and proliferation from the tendon proper.[17] Instead, repair relies heavily on extrinsic pathways, where synovial and bursal tissues provide fibroblasts and inflammatory cells, resulting in scar tissue formation with type III collagen that matures into disorganized type I collagen, often yielding inferior tensile strength compared to native tendon.[18] This extrinsic dominance explains the high retear rates in larger or chronic lesions, as scar tissue lacks the organized hierarchy of healthy rotator cuff fibers.
Signs and Symptoms
Patient-Reported Symptoms
Patients with rotator cuff tears commonly report shoulder pain as the primary symptom, often described as a dull ache located anteriorly in the shoulder that may radiate to the deltoid region or side of the arm.[19][2] This pain is frequently exacerbated by specific movements, such as abduction or internal/external rotation of the arm, and can become more pronounced with overhead activities like reaching or lifting objects.[19][20]Night pain is a particularly distressing feature, often worsening when lying on the affected side, which disrupts sleep and leads to significant fatigue.[2][19] Patients describe this as intense or excruciating, sometimes causing them to wake abruptly or scream in discomfort, with many resorting to propping the arm with pillows for relief.[21]Weakness is another frequent complaint, particularly noticeable during overhead tasks or when attempting to lift or rotate the arm, resulting in a sense of instability or inability to perform routine motions.[19][2] This perceived weakness contributes to broader functional limitations in activities of daily living, such as difficulty combing hair, dressing, or reaching behind the back, often forcing patients to adapt or avoid these tasks entirely.[19][21]The onset and progression of symptoms vary by tear type: traumatic tears typically present with acute, sudden pain and immediate weakness following an injury like a fall, whereas degenerative tears develop insidiously over time with gradual worsening from mild discomfort during activity to constant pain at rest.[19][2] In degenerative cases, patients may initially notice only intermittent pain that progresses to interfere with sleep and daily function, sometimes accompanied by a crunching sensation during movement.[21]
Clinical Examination Findings
During clinical examination of suspected rotator cuff tears, inspection often reveals atrophy in the supraspinatus or infraspinatus fossae, particularly in chronic cases where disuse leads to muscle wasting; this is more readily apparent in the infraspinatus due to its superficial position.[22]Atrophy is assessed through visual inspection and palpation for loss of muscle bulk in these fossae, serving as an objective sign of longstanding tendon disruption.[23]Impingement signs are key objective findings, with the Neer test eliciting pain during passive forward flexion of the arm with the scapula stabilized, indicating subacromial compression.[23] Similarly, the Hawkins-Kennedy test provokes pain by flexing the arm to 90 degrees and forcibly internally rotating the shoulder, also reflecting impingement and showing high sensitivity (72-92%) but variable specificity (44-78%).[23] These maneuvers help identify mechanical irritation of the rotator cuff tendons against the coracoacromial arch.[24]Specific strength tests demonstrate weakness associated with individual tendon involvement; the empty can test, performed by resisting downward pressure on the arm in 90 degrees of scaption with thumbs pointing down, assesses supraspinatus integrity and shows high sensitivity (88%) for tears, though specificity is moderate (62%).[25] The lift-off test evaluates the subscapularis by asking the patient to lift the hand away from the lower back against resistance; inability to do so indicates weakness, with low sensitivity (22%) but high specificity (94%) for full-thickness tears.[25]Range of motion assessment commonly uncovers deficits where active elevation and external rotation are limited more than passive motion, reflecting rotator cuff dysfunction rather than joint stiffness; for instance, active abduction may be restricted while passive remains near full.[23] This discrepancy highlights tendon insufficiency in powering shoulder movements.[22]Palpation during active motion may reveal crepitus or clicking over the rotator cuff, suggesting bursal inflammation or tendon irregularity; the crepitus test, involving fingertip palpation during arm movement, has a sensitivity of 67% and specificity of 80% for detecting tears, particularly in patients over 55 years.[26]
Causes and Risk Factors
Injury Mechanisms
Rotator cuff tears arise from distinct biomechanical events, primarily categorized as acute traumatic or chronic degenerative processes. Acute tears typically result from sudden, high-energy impacts that overwhelm the tendon's tensile strength, leading to full-thickness disruptions. In contrast, chronic tears develop gradually through repetitive subfailure loading, causing cumulative attritional damage to the tendon fibers.[20][1]Acute traumatic tears often occur in younger patients due to forceful events such as high-energy falls onto an outstretched arm or direct blows to the shoulder, which generate rapid shear and tensile forces across the rotator cuff. These mechanisms can produce complete tears, particularly involving the supraspinatus tendon, as the humeral head is abruptly displaced or the arm is hyperabducted under load. For instance, a fall from height or a collision in contact sports may cause immediate tendon avulsion from the greater tuberosity, disrupting the normal glenohumeral stability. Such injuries are less common than degenerative types but necessitate prompt intervention to prevent retraction and fatty infiltration.[20][1]Chronic overuse tears stem from repetitive microtrauma in activities involving overhead motions, such as baseball pitching, where the rotator cuff endures prolonged eccentric contractions to decelerate the arm. During the deceleration phase of throwing, the posterior rotator cuff muscles, including the infraspinatus and teres minor, contract eccentrically against high angular velocities—up to 7000 degrees per second—generating shear forces and intratendinous strain that initiate partial-thickness tears on the articular surface. Over time, this attritional wear progresses to full-thickness defects, exacerbated by internal impingement between the humeral head and glenoid labrum. Bony impingement further contributes, as a subacromial spur on the acromion compresses the cuff tendons during abduction, reducing the acromiohumeral distance to 1-3 mm and increasing contact pressure in the first 30-60 degrees of motion.[20][1][27]Iatrogenic rotator cuff tears represent a subset of injury mechanisms arising from surgical interventions on the shoulder, such as recurrent defects following arthroscopic repair due to suture failure or anchor displacement at the tendon-bone interface. These complications often arise from excessive bone resection during acromioplasty or aggressive rehabilitation that overloads the repair site. Such tears mimic acute presentations but are linked directly to procedural biomechanics, including inadvertent tendon iatrogenic injury during open repairs.[28][29]
Intrinsic and Extrinsic Factors
Intrinsic factors contribute to rotator cuff tear susceptibility by altering tendon composition and integrity from within. Age-related degeneration is a primary intrinsic risk, with the prevalence of tears increasing significantly after age 50 due to progressive collagen disorganization, reduced cellularity, and fatty infiltration in the rotator cuff tendons.[30] Vascular compromise, particularly hypovascularity in the critical zone 10-15 mm proximal to the tendon insertion, impairs nutrient supply and repair, predisposing to degenerative tears, especially on the articular side.[31] Genetic factors, such as variants in collagen genes like COL5A1 and extracellular matrix homeostasis genes (MMP1, MMP3), influence tendon strength and remodeling, with certain haplotypes (e.g., 2G/5A) conferring higher susceptibility to tears.[32][33] Comorbidities like diabetes mellitus and obesity accelerate tendon degeneration; diabetes leads to stiffness and reduced biomechanical properties through glycation, with affected individuals facing over twofold increased risk, while obesity (e.g., higher BMI) is associated with greater tear prevalence and severity, with each 5-unit BMI increase linked to 35% higher odds.[30][34] Hormonal influences, including estrogen decline in postmenopausal women, weaken tendon-to-bone interfaces and elevate tear rates, as lower estrogen levels correlate with higher surgical intervention needs.[35]Extrinsic factors involve external stressors that exacerbate tendon overload and impingement. Occupational repetitive strain, common in professions like painters and assembly line workers involving overhead reaching, forceful exertions, and awkward postures, doubles the risk through cumulative microtrauma and subacromial compression.[36][37]Smoking impairs tendon healing by inducing apoptosis, reducing vascularity, and promoting degenerative changes, with smokers exhibiting a dose-dependent risk elevation and larger tear sizes at presentation.[38] Anatomic variations, such as a hooked Type III acromion, increase impingement risk by narrowing the subacromial space, leading to higher rates of full-thickness tears compared to flat Type I morphologies.[39]
Diagnosis
History and Physical Tests
The clinical assessment of a rotator cuff tear begins with a detailed patient history to identify key features suggestive of the condition. Patients often report shoulder pain that may onset acutely following trauma, such as a fall or forceful overhead motion, or develop insidiously over time without a clear precipitating event, particularly in older individuals or those with repetitive overhead activities.[20] Aggravating factors typically include activities involving armelevation, such as reaching overhead or lifting, while night pain that disrupts sleep is a common complaint in chronic cases.[40] Prior injuries, including previous shouldertrauma or contralateral rotator cuff issues, should be documented, as they increase suspicion for bilateral or recurrent pathology.[41]Standardized physical tests are employed to assess rotator cuff integrity and localize potential tears. The Jobe's test, also known as the empty can test, involves resisted shoulder abduction at 90 degrees of elevation in the scapular plane with internal rotation (thumbs down); pain or weakness indicates supraspinatus involvement, with a sensitivity of approximately 53% and specificity of 82% for full-thickness tears.[23] The external rotation lag sign evaluates infraspinatus and teres minor function by passively placing the shoulder in maximal external rotation at 0 degrees abduction and observing for a lag upon active return, which is highly specific (up to 97%) for full-thickness tears of these muscles.[42] The belly-press test assesses subscapularis integrity by having the patient press their hand into their abdomen while keeping the elbow forward; inability to maintain pressure or internal rotation lag suggests a tear, with specificity around 88% for subscapularis pathology.[25]Pain is quantified using validated scales to guide assessment and monitor progression. The Visual Analog Scale (VAS), a 10 cm line from "no pain" to "worst possible pain," is commonly applied to rate shoulder pain at rest, with activity, and at night, providing a reliable measure with strong correlation to functional outcomes in rotator cuff disease.[43]Differential diagnosis considerations are essential to distinguish rotator cuff tears from mimicking conditions. Symptoms overlapping with superior labrum anterior to posterior (SLAP) tears or other labral pathologies, such as clicking or catching with overhead motion, necessitate targeted questioning to rule out intra-articular issues.[20] Similarly, cervical radiculopathy, often presenting with radicular pain into the arm and weakness from C5-C6 nerve root compression, must be excluded through history of neck pain, sensory changes, or positive cervical maneuvers.[44]Documentation of hand dominance and occupation provides context for risk and functional impact. Dominant-hand involvement is associated with higher tear prevalence due to increased use and load, while occupations involving heavy lifting or repetitive overhead work, such as construction or athletics, elevate risk and influence management decisions.[9]
Imaging Modalities
X-rays serve as the initial imaging modality for evaluating suspected rotator cuff tears, primarily to identify associated bony abnormalities such as acromial morphology, calcific tendinitis, or secondary signs of chronic tears like a reduced acromiohumeral distance (normal 8-12 mm).[45] Specific views, including the outlet view, help assess for impingement by visualizing the acromial shape and orientation.[45] While x-rays cannot directly depict soft tissue tears, they are cost-effective and widely available for screening purposes.[45]Ultrasound provides a dynamic, non-invasive assessment of tendon integrity and is particularly useful for detecting full-thickness rotator cuff tears with a sensitivity of 92.3% and specificity of 94.4%.[45] It excels in real-time evaluation during shoulder movement, allowing differentiation between partial- and full-thickness defects, where full-thickness tears appear as hypoechoic or anechoic gaps in the tendon.[45] For partial-thickness tears, sensitivity is lower at 66.7% with 93.5% specificity, and overall performance for any tear is approximately 81% sensitive and 82% specific, though it remains operator-dependent and cost-effective as a first-line option when MRI is unavailable.[45][46]Magnetic resonance imaging (MRI) is the gold standard for soft tissue visualization in rotator cuff tears, offering high-resolution depiction of partial tears, muscle atrophy, and tendon retraction with 90% sensitivity and 93% specificity for full-thickness tears.[45][46] T2-weighted sequences highlight fluid within tear defects, while overall sensitivity for any tear reaches 84% and specificity 86%, making it superior for surgical planning and outcome prediction compared to ultrasound.[46] For partial-thickness tears, plain MRI achieves 67% sensitivity and 94% specificity, improved to 83% sensitivity with MR arthrography.[45] Limitations include contraindications in patients with pacemakers or severe claustrophobia, high cost, and longer scan times.[45][46]Emerging technologies, such as artificial intelligence (AI) applications in MRI and ultrasound analysis, show promise in enhancing diagnostic accuracy by automating tear detection and classification, with systematic reviews indicating improved sensitivity and specificity in recent studies as of 2024-2025.[47][48]CT arthrography is employed for complex cases requiring detailed surgical planning, where intra-articular contrast injection reveals extravasation through full-thickness tears and assesses associated osseous or chondral structures with high accuracy.[49] It offers advantages over standard CT for soft tissue evaluation, particularly in postoperative settings to differentiate retears from scarring, though it involves radiation exposure and is less sensitive for subscapularis tears.[49] MR arthrography provides similar benefits with even higher sensitivity (up to 92%) for partial-thickness tears but shares invasive risks like contrast reactions.[49]
Tear Classification
Rotator cuff tears are classified using several systems that assess tear depth, size, location, and associated muscle changes to inform clinical decision-making and predict outcomes. These classifications, primarily derived from arthroscopic and imaging evaluations, help distinguish partial-thickness from full-thickness tears and quantify severity.The Ellman classification specifically addresses partial-thickness rotator cuff tears, categorizing them by depth and location. Depth is graded as follows: Grade I for tears less than 3 mm deep (involving less than 25% of tendon thickness), Grade II for tears 3-6 mm deep (25-50% thickness), and Grade III for tears greater than 6 mm deep (more than 50% thickness). Location is denoted as A for articular-sided (originating from the joint side), B for bursal-sided (from the subacromial bursa side), or C for intratendinous (within the tendon substance without surface involvement).[50]For full-thickness tears, the Cofield classification focuses on anteroposterior tear size measured at the thinnest point: small tears are less than 1 cm, medium tears range from 1-3 cm, large tears from 3-5 cm, and massive tears exceed 5 cm. This system emphasizes the extent of tendon detachment from the humeral head, aiding in surgical planning.[51]Fatty degeneration of the rotator cuff muscles, often accompanying chronic tears, is evaluated using the Goutallier staging system on MRI or CT scans. It grades supraspinatus and other muscles from stage 0 (normal musculature with no fatty infiltration) to stage 1 (some fatty streaks), stage 2 (less fat than muscle), stage 3 (as much fat as muscle), and stage 4 (more fat than muscle). Higher stages indicate advanced irreversible changes that complicate repair.[52]Tear location further refines classification, with articular-sided tears most common in degenerative cases due to hypovascularity in the critical zone, bursal-sided tears often linked to impingement, and intratendinous tears presenting as isolated intrasubstance disruptions without bursal or articular extension.[10]Prognostically, massive tears greater than 5 cm with significant tendon retraction are associated with poorer functional outcomes, higher retear rates after repair, and increased muscle atrophy, as retraction beyond 3 cm often correlates with irreversible fatty infiltration and pseudoparalysis.[53]
Prevention
Strengthening Exercises
Strengthening exercises play a crucial role in preventing rotator cuff tears by targeting the rotator cuff muscles and periscapular stabilizers to enhance endurance, balance, and overall shoulder stability, particularly in populations prone to overuse such as overhead athletes. These interventions address underlying risk factors like muscle weakness, promoting balanced force production around the glenohumeral joint to withstand repetitive stresses.[54]A primary exercise for supraspinatus strengthening is the side-lying external rotation using a theraband, performed with the elbow bent at 90 degrees and the arm abducted 0-30 degrees to isolate the muscle while minimizing impingement risk.[55] To execute, lie on the unaffected side, secure the theraband under the body or to a stable anchor, and rotate the forearm upward against resistance, keeping the elbow tucked to the side.[56]For scapular stabilization, rows—such as seated or prone theraband rows—and wall slides are recommended to bolster periscapular muscles including the rhomboids, middle trapezius, and serratus anterior, which provide a stable base for rotator cuff function. In rows, sit or lie with the theraband anchored at chest height, pull the elbows back while squeezing the shoulder blades together to promote retraction and depression. Wall slides involve standing against a wall, sliding the arms upward into flexion while maintaining contact between the forearms and wall to activate serratus anterior upward rotation.[54][57]Programs should progress systematically from isometric holds (e.g., maintaining external rotation against resistance for 5-10 seconds) to concentric and eccentric loading phases, structured as 3 sets of 10-15 repetitions per exercise to build progressive overload without exceeding tissue tolerance.[55] These sessions are ideally conducted 2-3 times weekly, always beginning with a 5-10 minute warm-up such as light aerobic activity or dynamic arm circles to increase blood flow and joint lubrication.[57]Evidence from cohort studies and consensus guidelines demonstrates that such preventive strengthening programs yield moderate to large effects in reducing shoulder injury risk, including rotator cuff tears, by up to 50% in overhead athletes through improved muscle balance and load distribution.[58]
Lifestyle and Occupational Modifications
Lifestyle and occupational modifications play a crucial role in mitigating the risk of rotator cuff tears by addressing environmental and habitual factors that contribute to shoulderstrain. These strategies focus on adapting daily routines and work environments to minimize repetitive stress and biomechanical overload on the rotator cuff tendons, without relying on physical training interventions.Ergonomic adjustments in occupational settings are essential for preventing shoulder overuse. Positioning tools and work surfaces at elbow level promotes neutral shoulder postures, reducing muscle fatigue and the likelihood of impingement.[59] Similarly, avoiding overhead reaching during tasks, such as in construction or assembly work, decreases elevated arm positions that increase rotator cuff tension and degeneration risk.[60] Implementing these changes, like using adjustable workstations or lift-assist devices, has been shown to lower the incidence of work-related musculoskeletal disorders affecting the shoulder.[61]Smoking cessation represents a key lifestyle modification for rotator cuff health, as tobacco use impairs tendon quality through reduced blood supply and heightened oxidative stress. Smokers experience rotator cuff tears nearly twice as large as those in nonsmokers, attributable to compromised tendon integrity.[62] Quitting smoking is advisable to improve musculoskeletal health outcomes.[62]Weight management is another vital strategy, particularly for countering the mechanical burdens imposed by obesity on the shoulder. Excess body mass elevates the load on the subacromial space during arm elevation, accelerating rotator cuff impingement and tear progression.[63]Abdominal obesity specifically correlates with higher prevalence of shoulder pain and chronic rotator cuff tendinitis, with increased waist circumference serving as a predictor in population studies.[64] Sustained weight loss through dietary adjustments reduces this subacromial impingement risk, promoting long-term shoulder stability.In repetitive occupations, activity pacing via alternating heavy and light tasks prevents cumulative shoulder fatigue. This approach distributes workload to allow tendon recovery, significantly decreasing the onset of work-related shoulder disorders compared to continuous repetitive motions.[65]Job rotation strategies, where workers switch between varying intensity activities, further mitigate overuse by limiting prolonged exposure to high-demand shoulder postures.[66]For individuals in contact sports, protective equipment such as shoulder padding provides essential shielding for the shoulder against direct impacts. Padded shoulder guards or braces absorb collision forces in high-risk activities like football or wrestling.[67] Consistent use of properly fitted gear, combined with technique training, enhances overall shoulder resilience in these environments.[68]
Treatment
Non-Surgical Approaches
Non-surgical approaches represent the initial management strategy for rotator cuff tears, particularly in cases where symptoms are manageable and surgical risks outweigh benefits. These conservative treatments aim to alleviate pain, reduce inflammation, and restore shoulder function through a combination of lifestyle adjustments, medications, and targeted rehabilitation. Such methods are often prioritized for partial-thickness tears, which involve less than 50% of the tendon thickness, as well as for patients with low physical demands or contraindications to surgery, such as advanced age or comorbidities.[1][69]Activity modification and rest are foundational to non-surgical care, focusing on minimizing impingement and allowing tendon healing. Patients are advised to avoid overhead activities, heavy lifting, and repetitive motions that exacerbate pain, while incorporating periods of relative rest to reduce stress on the rotator cuff. This approach, combined with patient education on ergonomics, can significantly decrease symptoms without invasive intervention.[1][69]Pharmacotherapy plays a key role in controlling inflammation and pain. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or naproxen, are commonly prescribed to reduce swelling and discomfort, providing symptomatic relief in the acute phase. Subacromial corticosteroid injections, typically a mixture of cortisone and a local anesthetic, offer targeted relief by decreasing inflammation in the subacromial space; these provide short-term pain relief in many patients, with benefits lasting at least 3-6 months. However, due to risks of tendon weakening and potential adverse effects on rotator cuff integrity, injections are limited to no more than 3-4 per year.[1][69][70]Physical therapy forms the cornerstone of rehabilitation, emphasizing gentle mobilization and strengthening over 6-12 weeks to improve range of motion, posture, and muscle support around the shoulder. Programs often include pendulum exercises, where the arm is gently swung in circular motions while leaning forward to promote passive mobility without stressing the cuff, alongside posture correction techniques like scapular setting to align the shoulder blades and reduce impingement. Strengthening focuses on the deltoid and periscapular muscles through progressive resistance, transitioning from supervised sessions to home exercises for sustained gains.[55][69][71]Indications for pursuing non-surgical approaches include partial tears, elderly or low-demand individuals, and scenarios where surgery is contraindicated, such as poor overall health or patient preference against operative risks. These methods yield success rates of 50-80% in providing symptom relief and functional improvement for small or partial tears, though outcomes may vary with tear chronicity and patient adherence. In many cases, non-surgical treatment achieves pain reduction and functional equivalence to surgery at 2-year follow-up, supporting its role as a primary option.[1][72][73]
Surgical Techniques
Surgical techniques for rotator cuff tears primarily aim to reattach the torn tendon to the humeral head while addressing associated pathology such as impingement. Indications for surgery typically include symptomatic full-thickness tears in active patients under 65 years old, particularly when conservative management has failed to alleviate pain and restore function.[74][75]Arthroscopic repair is the most common approach for smaller to medium-sized tears, utilizing either a mini-open or all-arthroscopic method. In the all-arthroscopic technique, small incisions allow insertion of an arthroscope and instruments to perform debridement of the torn tendon edges, mobilization of the tendon, and reattachment using suture anchors inserted into the humeral bone. This minimally invasive method provides better visualization of the joint and reduces postoperative pain compared to traditional open surgery.[76][77]For massive or irreparable tears, open repair may be necessary, often involving tendon transfers to restore shoulder mechanics. A common procedure is the latissimus dorsi tendon transfer, where the tendon is detached from its insertion on the humerus, rerouted over the superior aspect of the shoulder, and fixed to the greater tuberosity or supraspinatus fossa to compensate for the deficient rotator cuff. This technique is indicated for patients with significant functional deficits and poor tendon quality.[78][79]Acromioplasty is sometimes performed concurrently to address extrinsic impingement that may contribute to the tear; this involves subacromial decompression by shaving the undersurface of the acromion and resecting the coracoacromial ligament, creating more space for the rotator cuff tendons and reducing friction during shoulder motion. However, the routine use of acromioplasty as a concomitant treatment is not recommended for therapeutic benefit compared to arthroscopic repair alone, per the American Academy of Orthopaedic Surgeons (AAOS) Clinical Practice Guideline as of 2025. The procedure is typically done arthroscopically to minimize tissue disruption when indicated.[79][80][81]Fixation during repair can utilize single-row or double-row suture configurations. Single-row techniques anchor the tendon with a single line of anchors along the medial aspect of the footprint, while double-row repairs add a second row laterally to compress the tendon against the bone, restoring a broader contact area. Biomechanical studies demonstrate that double-row fixation provides superior initial strength, gap resistance, and load to failure compared to single-row, potentially leading to improved healing rates, though clinical outcomes may vary based on tear size.[82][83]
Biologic and Adjunctive Therapies
Biologic and adjunctive therapies for rotator cuff tears aim to enhance tendon healing through regenerative mechanisms, often serving as supplements to surgical repair or non-operative management. These approaches leverage growth factors, cellular components, and scaffolds to promote tissue regeneration, reduce inflammation, and improve biomechanical integrity in damaged rotator cuffs. The 2025 AAOS Clinical Practice Guideline highlights the role of biologics in optimizing the healing environment for rotator cuff injuries. While promising, their efficacy varies, with evidence derived primarily from randomized controlled trials (RCTs) and systematic reviews.[84]Platelet-rich plasma (PRP) involves injecting autologous plasma concentrated with platelets to deliver growth factors such as platelet-derived growth factor (PDGF), which stimulate tendon regeneration and collagen synthesis. In RCTs, intraoperative PRP application during arthroscopic rotator cuff repair has been associated with reduced retear rates and improved clinical outcomes compared to repair alone, with one meta-analysis of 23 trials reporting significant decreases in retears. For partial-thickness rotator cuff tears, PRP injections alleviate pain in both short- and long-term follow-ups, though evidence remains mixed for full-thickness tears without surgery. Leukocyte-rich PRP variants show clinical benefits in repair augmentation, including better tendon healing in meta-analyses of RCTs.Stem cell therapy, particularly using mesenchymal stem cells (MSCs) harvested from bone marrow or adipose tissue, targets anti-inflammatory effects and tissue repair by differentiating into tenocytes and modulating the local microenvironment. Clinical trials demonstrate that MSC augmentation in rotator cuff repair improves tendon integrity and healing rates, with one RCT reporting complete tear resolution in some patients following intra-tendinous injections. MSCs exhibit pleiotropic effects, including suppression of pro-inflammatory cytokines, which aids in chronic tear management, though long-term safety concerns like potential tumorigenicity require further study in ongoing trials. As of 2025, adipose-derived micro-fragmented MSCs are being evaluated in phase II trials for enhancing recovery post-repair.Extracellular matrix (ECM) scaffolds, derived from decellularized animal or human tissues, act as augmentation patches to provide a structural framework for cellular ingrowth and remodeling in chronic rotator cuff tears. These bioabsorbable scaffolds support healing in large-to-massive tears by promoting fibrocartilage formation and reducing failure rates, with clinical studies showing improved tendon thickness and lower retear incidence compared to non-augmented repairs. Dermal matrix variants have demonstrated comparable outcomes to synthetic options in revision surgeries for poor-quality tissue. Often integrated during arthroscopic procedures, ECM scaffolds are particularly indicated for tears with retraction or fatty infiltration.Prolotherapy employs hypertonic dextrose injections to induce localized fibrosis and strengthen ligamentous structures around the rotator cuff, thereby stabilizing the joint. In patients with failed prior repairs, prolotherapy significantly improves shoulder function, reduces pain, and enhances satisfaction, as evidenced by prospective studies. For chronic rotator cuff disease, a single 20% dextrose injection provides analgesia and functional gains, with RCTs confirming benefits over placebo in pain-related outcomes. Hypertonic dextrose specifically targets tendinopathy by stimulating repair without surgical intervention.Preclinical studies as of 2025 explore gene therapy approaches aimed at inhibiting matrix metalloproteinases (MMPs), enzymes that degrade tendon extracellular matrix in rotator cuff tears. Models using gene-modified MSCs to suppress MMP-13 expression have shown enhanced fibrocartilage formation and reduced degeneration, paving the way for potential clinical translation. These approaches, often combined with stem cell delivery, represent high-impact contributions to biologic augmentation, though human trials remain in early phases.
Rehabilitation
Acute Phase Protocols
The acute phase of rehabilitation following rotator cuff tear treatment emphasizes tissue protection, pain reduction, and initiation of controlled mobility to facilitate healing while minimizing complications such as stiffness or retear. For patients undergoing surgical repair, immobilization is a cornerstone, typically involving sling use for 4-6 weeks to offload the repair site and promote tendon-to-bone healing.[85] During this period, passive range of motion (PROM) exercises are introduced cautiously, often starting within the first week for small-to-medium tears, to prevent adhesions without compromising the repair.[86]Pain management in this phase relies on non-invasive modalities, including intermittent cryotherapy or ice application for 15-20 minutes several times daily to reduce swelling and discomfort, alongside arm elevation when possible to minimize edema. Gentle pendulum exercises—where the arm hangs freely and swings passively in forward-backward, side-to-side, and circular motions—are commonly prescribed to maintain joint lubrication and deltoid activation without active shouldermuscle contraction.[55] These interventions align with broader treatment approaches, such as arthroscopic repair or conservative management, but are tailored to the acute postoperative window.[85]The primary goals are to safeguard the healing tissue, avert shoulder stiffness through gradual PROM progression, and preserve deltoid and periscapular muscle activation via isometric holds or scapular setting exercises. This phase spans 0-6 weeks, with weekly physical therapist monitoring to assess pain levels, ROM, and compliance, adjusting intensity based on individual healing responses.[86] For non-surgical cases, protocols adapt similarly but incorporate earlier active-assisted ROM (e.g., using a wand or pulley for elevation) after 1-2 weeks, often without prolonged sling use, to accelerate mobility while focusing on pain control and postural correction.[71]
Long-Term Recovery Strategies
The intermediate phase of rehabilitation following rotator cuff repair, typically spanning 6 to 12 weeks postoperatively, focuses on transitioning from active-assisted to active range of motion (ROM) exercises while incorporating isometric strengthening to build foundational stability without compromising the repair site.[87] During this period, patients progress to supine or standing active ROM in forward flexion and external rotation, progressing to resisted isometric exercises for the rotator cuff and scapular stabilizers once passive ROM goals are met, aiming to restore functional shoulder mechanics.[88]In the advanced phase, beginning after 12 weeks, rehabilitation emphasizes sport-specific drills and plyometric exercises tailored for overhead athletes to enhance dynamic control, power, and endurance, with gradual integration of resistance bands and light weights to simulate occupational or athletic demands.[87] This phase includes proprioceptive neuromuscular facilitation and closed-chain exercises to improve neuromuscular coordination, ensuring patients achieve symmetrical shoulder function before advancing to unrestricted activities.[88]Progression between phases is guided by specific criteria, including achievement of full active ROM, at least 4/5 manual muscle strength across shoulder planes, and absence of pain during daily activities or resisted testing, which helps mitigate retear risk while promoting tissue adaptation.[89] Recent evidence as of 2025 supports variations in protocols, such as selective sling avoidance and early passive mobilization within 2-4 weeks for suitable patients to optimize recovery without increasing retear risk.[90]Healing assessment during long-term recovery often involves ultrasound or MRI imaging at 3 to 6 months postoperatively to evaluate tendon integrity, muscle atrophy, and fatty infiltration, providing objective data to adjust rehabilitation intensity and confirm repair maturation. These modalities correlate well with clinical outcomes, allowing clinicians to detect early complications like retears, which occur in approximately 15-20% of cases within this timeframe.[91]Return-to-work guidelines post-rotator cuff repair recommend initiating light-duty assignments, such as desk work without overhead reaching, around 3 months when basic strength and ROM are restored, with progression to full duties involving manual labor between 6 and 12 months, contingent on individualized functional testing and occupational demands.[92] This phased approach supports up to 77% of patients resuming full work by 6 months, emphasizing ergonomic modifications to prevent re-injury.[93]
Prognosis
Short-Term Outcomes
Short-term outcomes following treatment for rotator cuff tears primarily focus on pain relief, functional restoration, tendon healing, and early complications within the first 3 to 12 months. Surgical repair, such as arthroscopic techniques, generally yields superior results compared to non-surgical approaches in these metrics, though individual responses vary based on tear characteristics and patient factors.[94]Pain reduction is a key indicator of success, with surgical interventions achieving significant improvements in 82% to 97% of patients within 6 months, often measured by visual analog scale (VAS) scores decreasing by an average of 4-6 points on a 10-point scale. In contrast, non-surgical management, including physical therapy and corticosteroid injections, results in moderate pain relief for approximately 50-60% of patients at the same timeframe, with VAS reductions typically around 2-3 points. Meta-analyses confirm that surgery provides a statistically significant advantage in pain scores at 6 months (mean difference of -0.59 on VAS favoring repair), though the clinical magnitude may be modest for some.[95][94][96]Functional outcomes, assessed via scores like the Constant-Murley (CMS) or American Shoulder and Elbow Surgeons (ASES) scale, show marked improvements post-treatment, often reaching 75-90% of normal shoulder function within 6-12 months. For instance, CMS scores commonly rise from preoperative levels of 40-50 to 75-85 postoperatively, while ASES scores improve from around 50 to 85-90, indicating substantial gains in range of motion, strength, and daily activities. These enhancements are more pronounced after surgical repair, targeting over 80% of normative values for small to medium tears.[97][98][99]Tendon healing rates, evaluated by MRI at 1 year, approximate 80-90% integrity for small tears following repair, with retear rates of 10-15% for single- or double-row techniques in medium to large tears. Early complications within the first 3 months include shoulder stiffness in about 8-10% of cases and infection in less than 1%, both of which can delay recovery but are often manageable with targeted rehabilitation or debridement. Younger age and smaller tear size are strong predictors of better short-term success, with healing rates dropping by 20-30% for tears over 3 cm or in patients above 65 years.[100][101][102][103]
Long-Term Complications
One of the primary long-term complications following rotator cuff repair is re-tear, particularly in cases of massive tears where rates range from 20% to 50%, often attributed to poor tendon quality and fatty infiltration that compromises healing integrity.[104][105] These re-tears can lead to persistent pain, reduced shoulder function, and the need for further intervention, with studies indicating that patients with re-tears exhibit significantly worse long-term outcome scores compared to those with intact repairs.[104]Rotator cuff arthropathy represents another significant delayed adverse effect, characterized by eccentric superior migration of the humeral head due to chronic rotator cuff deficiency, which results in abnormal glenohumeral joint loading and progressive osteoarthritis.[106] This condition develops over years as the unopposed deltoid force causes acetabularization of the acromion and erosion of the glenoid, exacerbating joint degeneration and leading to substantial functional limitations in affected individuals.[107]Secondary adhesive capsulitis, commonly known as frozen shoulder, can emerge as a complication in approximately 5-10% of rotator cuff tear cases, particularly following injury or surgery, where inflammation and fibrosis in the glenohumeral capsule restrict motion and prolong recovery.[108] This stiffness often manifests months after the initial tear, contributing to chronic disability if not addressed through targeted physical therapy or manipulation under anesthesia.Nerve injuries, such as axillary nerve palsy, occur postoperatively in rotator cuff surgery with an incidence of 1-2%, potentially due to traction, compression, or direct trauma during arthroscopic procedures, leading to deltoid weakness and sensory deficits that may persist long-term.[109] Although many cases resolve spontaneously, persistent neuropathy in up to 20% of instances can necessitate nerve conduction studies and, in severe cases, neurolysis or tendon transfers to restore function.[110]Management of these long-term failures typically involves revision surgery for re-tears amenable to re-repair, though success rates are lower in massive cases due to tissue degeneration; alternatively, reverse shoulder arthroplasty is increasingly utilized for irreparable rotator cuff deficiencies and arthropathy, providing pain relief and improved active elevation in 80-90% of patients.[111][112] Patient selection for these interventions emphasizes older individuals with low functional demands to optimize outcomes and minimize further complications.[112]
Epidemiology
Incidence Rates
Rotator cuff tears are highly prevalent in older populations, with studies indicating that 20-30% of asymptomatic adults over the age of 60 exhibit evidence of tears on imaging, increasing progressively with age.[113] By age 80 and older, the prevalence rises sharply to approximately 62-80% among asymptomatic individuals.[114][115] These figures are derived from cadaveric and MRI-based investigations that highlight the degenerative nature of many tears, often without clinical symptoms.[116]In the general population, the annual incidence of shoulder disorders, many involving rotator cuffpathology including tears, is estimated at 1% (10 per 1,000 individuals), peaking at around 2.5% in middle adulthood.[31] For acute full-thickness tears confirmed by MRI, the rate is lower, at approximately 0.016-0.025% (16-25 per 100,000) in adults aged 18-75.[117] Among athletes, particularly overhead throwers, the prevalence of rotator cuff tears is notably higher, reaching up to 40% even in asymptomatic cases due to repetitive tensile overload.[118]Asymptomatic rotator cuff tears are common in middle-aged individuals, with imaging studies showing a prevalence ranging from 20-40%.[116] In the United States, approximately 570,000 rotator cuff repair surgeries were performed in 2023, reflecting the clinical burden of symptomatic cases and increasing trends due to improved diagnostics and an aging population.[119][120]Diagnosis rates of rotator cuff tears have increased over recent decades, attributable to the widespread adoption of advanced imaging modalities such as MRI and ultrasound, which enhance detection of both symptomatic and incidental tears.[121] This trend underscores the importance of distinguishing degenerative findings from those requiring intervention.
Demographic Variations
Rotator cuff tears exhibit significant variations across demographic groups, with age being the most prominent factor influencing prevalence. The incidence of full-thickness rotator cuff tears is negligible in individuals under 50 years, at 0% for those in their 20s to 40s, but rises sharply thereafter, reaching 10.7% in the 50s, 15.2% in the 60s, 26.5% in the 70s, and 36.6% in the 80s.[122] Overall prevalence in the general population is approximately 22%, increasing to as high as 80% in those over 80 years old, reflecting age-related degenerative changes in tendon integrity.[123] Patients with bilateral tears present at an average age of 67.8 years, compared to 58.7 years for unilateral tears and 48.7 years for those without tears.[124]Gender differences in prevalence are modest but notable in certain age groups. Full-thickness tears occur in 25.2% of males versus 19.7% of females in the general population, with males showing higher rates in their 50s (p < 0.0001) and 60s (p = 0.0099), though differences diminish in the 70s and 80s.[122] However, some studies report no significant gender disparity in tear prevalence or symptomatic presentation.[124] Women tend to seek surgical intervention later, with a mean age of 74.4 years compared to 70.1 years for men (p = 0.001), and they comprise about 75% of cases in advanced rotator cuff tear arthropathy requiring reverse shoulder arthroplasty.[125] In surgical cohorts, males predominate, accounting for 69.2% of rotator cuff repair patients.[126]Occupational factors contribute to demographic variations, particularly among those in physically demanding roles. Tears are more common in individuals engaged in heavy manual labor, repetitive overhead arm motions, or exposure to vibration and awkward postures, such as in construction, manufacturing, or healthcare settings involving lifting.[127][2] These risks disproportionately affect working-age adults in such occupations, with dominant arm involvement more frequent among heavy laborers.[128]Data on racial and ethnic variations in incidence are limited, but disparities appear in symptom severity and treatmentaccess. In New Zealand cohorts, Māori patients (5.4% of surgical cases) present younger (average 51 years versus 58 overall) and report higher pain scores (5.7 versus 4.7, p < 0.01) and lower function (Flex-SF score 23.0 versus 24.4, p = 0.03) compared to Europeans (89.8%).[126] In the United States, racial minorities, including Black or African American, Hispanic, and Asian individuals, face lower rates of operative management for tears, even after adjusting for socioeconomic factors, suggesting barriers beyond incidence.[129]